Antibiotics, Vol. 9, Pages 57: The Evaluation of Antibiotic Consumption at the Inpatient Level in Kazakhstan from 2011 to 2018 Antibiotics doi: 10.3390/antibiotics9020057 Authors: Zhussupova Skvirskaya Reshetnikov Dragojevic-Simic Rancic Utepova Jakovljevic Antimicrobial agents have a rather special position due to their importance as essential medicines for the treatment of infectious diseases. Evidence-based prescriptions are needed to optimize the use of antimicrobials...
Sun Feb 02, 2020 02:00
Antibiotics, Vol. 9, Pages 56: Antibiotic Delivery Strategies to Treat Skin Infections When Innate Antimicrobial Defense Fails Antibiotics doi: 10.3390/antibiotics9020056 Authors: Smith Russo Fiegel Brogden The epidermal skin barrier protects the body from a host of daily challenges, providing protection against mechanical insults and the absorption of chemicals and xenobiotics. In addition to the physical barrier, the epidermis also presents an innate defense against microbial...
Sat Feb 01, 2020 02:00
Antibiotics, Vol. 9, Pages 55: A 28 Day Clinical Assessment of a Lactic Acid-containing Antimicrobial Intimate Gel Wash Formulation on Skin Tolerance and Impact on the Vulvar Microbiome Antibiotics doi: 10.3390/antibiotics9020055 Authors: Bruning Chen McCue Rubino Wilkinson Brown While intimate feminine hygiene products are widely used as part of daily cleansing routines, little is known about how these products impact the vulvovaginal area and its microbiome stability....
Sat Feb 01, 2020 02:00
Antibiotics, Vol. 9, Pages 52: Antimicrobial Resistance and Food Animals: Influence of Livestock Environment on the Emergence and Dissemination of Antimicrobial Resistance Antibiotics doi: 10.3390/antibiotics9020052 Authors: Vidovic Vidovic The emergence and dissemination of antimicrobial resistance among human, animal and zoonotic pathogens pose an enormous threat to human health worldwide. The use of antibiotics in human and veterinary medicine, and especially the use of large...
Fri Jan 31, 2020 02:00
Antibiotics, Vol. 9, Pages 53: Oxygen-Independent Antimicrobial Photoinactivation: Type III Photochemical Mechanism? Antibiotics doi: 10.3390/antibiotics9020053 Authors: Hamblin Abrahamse Since the early work of the 1900s it has been axiomatic that photodynamic action requires the presence of sufficient ambient oxygen. The Type I photochemical pathway involves electron transfer reactions leading to the production of reactive oxygen species (superoxide, hydrogen peroxide, and hydroxyl...
Fri Jan 31, 2020 02:00
Antibiotics, Vol. 9, Pages 54: Machine Learning and Multidrug-Resistant Gram-Negative Bacteria: An Interesting Combination for Current and Future Research Antibiotics doi: 10.3390/antibiotics9020054 Authors: Daniele Roberto Giacobbe Sara Mora Mauro Giacomini Matteo Bassetti The dissemination of multidrug-resistant Gram-negative bacteria (MDR-GNB) is associated with increased morbidity and mortality in several countries. Machine learning (ML) is a branch of artificial intelligence...
Fri Jan 31, 2020 02:00
Antibiotics, Vol. 9, Pages 50: Using Machine Learning Techniques to Aid Empirical Antibiotic Therapy Decisions in the Intensive Care Unit of a General Hospital in Greece Antibiotics doi: 10.3390/antibiotics9020050 Authors: Georgios Feretzakis Evangelos Loupelis Aikaterini Sakagianni Dimitris Kalles Maria Martsoukou Malvina Lada Nikoletta Skarmoutsou Constantinos Christopoulos Konstantinos Valakis Aikaterini Velentza Stavroula Petropoulou Sophia Michelidou Konstantinos...
Fri Jan 31, 2020 02:00
Antibiotics, Vol. 9, Pages 51: Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? Antibiotics doi: 10.3390/antibiotics9020051 Authors: Despoina Koulenti Kostoula Arvaniti Mathew Judd Natasha Lalos Iona Tjoeng Elena Xu Apostolos Armaganidis Jeffrey Lipman Ventilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration...
Fri Jan 31, 2020 02:00
Antioxidants, Vol. 9, Pages 128: Bridelia speciosa Müll.Arg. Stem bark Extracts as a Potential Biomedicine: From Tropical Western Africa to the Pharmacy Shelf Antioxidants doi: 10.3390/antiox9020128 Authors: Mahomoodally Sinan Bene Zengin Orlando Menghini Veschi Chiavaroli Recinella Brunetti Leone Angelini Hubka Covino Venanzoni Picot-Allain Lellis Cama Cziáky Jekő Ferrante Bridelia species have been used...
Sun Feb 02, 2020 02:00
Antioxidants, Vol. 9, Pages 127: A Novel Pectic Polysaccharide of Jujube Pomace: Structural Analysis and Intracellular Antioxidant Activities Antioxidants doi: 10.3390/antiox9020127 Authors: Ximeng Lin Keshan Liu Sheng Yin Yimin Qin Peili Shen Qiang Peng After extraction from jujube pomace and purification by two columns (DEAE-Sepharose Fast Flow and Sepharcyl S-300), the structure of SAZMP4 was investigated by HPGPC, GC, FI-IR, GC-MS, NMR, SEM, and AFM. Analysis determined...
Sun Feb 02, 2020 02:00
Antioxidants, Vol. 9, Pages 126: The Astaxanthin Aggregation Pattern Greatly Influences Its Antioxidant Activity: A Comparative Study in Caco-2 Cells Antioxidants doi: 10.3390/antiox9020126 Authors: Mingqin Dai Chunjun Li Zhao Yang Zhe Sui Jing Li Ping Dong Xingguo Liang Astaxanthin is an excellent antioxidant that can form unstable aggregates in biological or artificial systems. The changes of astaxanthin properties caused by molecular aggregation have gained much...
Sun Feb 02, 2020 02:00
Antioxidants, Vol. 9, Pages 121: Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H2O2-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway Antioxidants doi: 10.3390/antiox9020121 Authors: Qi Jiang Zhang Zhang Wang Pregnancy complications are associated with oxidative stress induced by accumulation of trophoblastic ROS in the placenta. We employed the human trophoblast HTR8/SVneo cell line to determine the effect of curcumin pre-treatment on H2O2-induced...
Sat Feb 01, 2020 02:00
Antioxidants, Vol. 9, Pages 124: Dicarbonyl Stress and S-Glutathionylation in Cerebrovascular Diseases: A Focus on Cerebral Cavernous Malformations Antioxidants doi: 10.3390/antiox9020124 Authors: Cinzia Antognelli Andrea Perrelli Tatiana Armeni Vincenzo Nicola Talesa Saverio Francesco Retta Dicarbonyl stress is a dysfunctional state consisting in the abnormal accumulation of reactive α-oxaldehydes leading to increased protein modification. In cells, post-translational...
Sat Feb 01, 2020 02:00
Antioxidants, Vol. 9, Pages 125: Blueberry Juice Antioxidants Protect Osteogenic Activity against Oxidative Stress and Improve Long-Term Activation of the Mineralization Process in Human Osteoblast-Like SaOS-2 Cells: Involvement of SIRT1 Antioxidants doi: 10.3390/antiox9020125 Authors: Vladana Domazetovic Gemma Marcucci Irene Falsetti Anna Rita Bilia Maria Teresa Vincenzini Maria Luisa Brandi Teresa Iantomasi Diets rich in fruits and vegetables with many antioxidants...
Sat Feb 01, 2020 02:00
Antioxidants, Vol. 9, Pages 122: Antioxidant Effect of Alpha-Lipoic Acid in 6-Hydroxydopamine Unilateral Intrastriatal Injected Rats Antioxidants doi: 10.3390/antiox9020122 Authors: Pavlina Andreeva-Gateva Lubomir Traikov Zafer Sabit Dimitar Bakalov Radka Tafradjiiska-Hadjiolova The toxin 6-hydroxydopamine (6-OHDA) is a highly oxidizable dopamine (DA) analog that is widely used for reproducing several cell processes identified in Parkinson’s disease (PD). Due to...
Sat Feb 01, 2020 02:00
Antioxidants, Vol. 9, Pages 123: UHPLC-HESI-OT-MS-MS Biomolecules Profiling, Antioxidant and Antibacterial Activity of the “Orange-Yellow Resin” from Zuccagnia punctata Cav. Antioxidants doi: 10.3390/antiox9020123 Authors: Jessica Gómez Mario J. Simirgiotis Sofía Manrique Beatriz Lima Jorge Bórquez Gabriela E. Feresin Alejandro Tapia This research was designed to investigate the metabolite profiling, phenolics, and flavonoids content as well as the potential antioxidant...
Sat Feb 01, 2020 02:00
Antioxidants, Vol. 9, Pages 120: Dendropanax morbifera Leaf Polyphenolic Compounds: Optimal Extraction Using the Response Surface Method and Their Protective Effects against Alcohol-Induced Liver Damage Antioxidants doi: 10.3390/antiox9020120 Authors: Taekil Eom Kyeoung Cheol Kim Ju-Sung Kim The response surface methodology was used to optimally extract the antioxidant substances from Dendropanax morbifera leaves. The central composite design was used to optimally analyze the effects...
Sat Feb 01, 2020 02:00
Atmosphere, Vol. 11, Pages 156: Current State of Atmospheric Aerosol Thermodynamics and Mass Transfer Modeling: A Review Atmosphere doi: 10.3390/atmos11020156 Authors: Kirill Semeniuk Ashu Dastoor A useful aerosol model must be able to adequately resolve the chemical complexity and phase state of the wide particle size range arising from the many different secondary aerosol growth processes to assess their environmental and health impacts. Over the past two decades, significant advances...
Sat Feb 01, 2020 02:00
Atmosphere, Vol. 11, Pages 155: The Combination of Wildfire and Changing Climate Triggers Permafrost Degradation in the Khentii Mountains, Northern Mongolia Atmosphere doi: 10.3390/atmos11020155 Authors: Munkhjargal Yadamsuren Yamkhin Menzel High topographic heterogeneity and complex mechanisms between the atmosphere and the ground create unique hydro-climatic processes over mountainous regions. Based on in situ observations, we present the spatial variability of ground...
Fri Jan 31, 2020 02:00
Behavioral Sciences, Vol. 10, Pages 48: What Makes a Partner Ideal, and for Whom? Compatibility Tests, Filter Tests, and the Mating Stability Matrix Behavioral Sciences doi: 10.3390/bs10020048 Authors: Lorenza Lucchi Basili Pier Luigi Sacco We introduce a typological characterization of possible human heterosexual couples in terms of the concordance-opposition of the orientations of their active and receptive areas as defined by the tie-up theory. We show that human mating incentives,...
Sun Feb 02, 2020 02:00
Behavioral Sciences, Vol. 10, Pages 47: Acute Sleep Curtailment Increases Sweet Taste Preference, Appetite and Food Intake in Healthy Young Adults: A Randomized Crossover Trial Behavioral Sciences doi: 10.3390/bs10020047 Authors: Tajiri Yoshimura Hatamoto Shiratsuchi Tanaka Shimoda This study aimed to examine the effect of acute sleep curtailment on sweet taste preference, appetite and food intake, and the correlation between food intake and sweet taste preference...
Sat Feb 01, 2020 02:00
Behavioral Sciences, Vol. 10, Pages 46: Factors which Influence Risk Taking and the Evolution of Social-Identity in Stroke Narratives: A Thematic Synthesis Behavioral Sciences doi: 10.3390/bs10020046 Authors: Richard Higgs Andrew Soundy Background: The disruption of a stroke can impact an individual’s sense of social identity. A comprehensive review is required to understand the factors and processes that influence changes in social identity following a stroke. Aims: To...
Fri Jan 31, 2020 02:00
Biology, Vol. 9, Pages 24: High-Fat Diet Propelled AOM/DSS-Induced Colitis-Associated Colon Cancer Alleviated by Administration of Aster glehni via STAT3 Signaling Pathway Biology doi: 10.3390/biology9020024 Authors: Bo-Ram Jin Kyung-Sook Chung Minho Lee Hyo-Jin An Many epidemiological observational studies suggest that a high-fat diet (HFD) accelerates the risk of colorectal cancer (CRC). Inflammation can play a key role in the relationship between colon cancer and HFD. Although...
Sun Feb 02, 2020 02:00
Biology, Vol. 9, Pages 23: Value of SUVmax for the Prediction of Bone Invasion in Oral Squamous Cell Carcinoma Biology doi: 10.3390/biology9020023 Authors: Stephanie A. Stalder Paul Schumann Martin Lanzer Martin W. Hüllner Niels J. Rupp Martina A. Broglie Grégoire B. Morand In advanced oral squamous cell carcinoma (OSCC), accurate planning of surgical resection and reconstruction are crucial for outcome and postoperative function. For OSCC close to the maxilla or mandible,...
Sun Feb 02, 2020 02:00
Biomolecules, Vol. 10, Pages 219: The Link between Homocysteine and Omega-3 Polyunsaturated Fatty Acid: Critical Appraisal and Future Directions Biomolecules doi: 10.3390/biom10020219 Authors: Rizzo Laganà Omega-3 polyunsaturated fatty acids and B vitamins are linked to metabolic and degenerative disorders, such as cardiovascular disease and cognitive decline. In the last two decades, the interplay between B vitamins and omega-3 polyunsaturated fatty acids gained increasing attention....
Sun Feb 02, 2020 02:00
Biomolecules, Vol. 10, Pages 220: Preliminary Studies on the Application of Grape Seed Extract in the Dyeing and Functional Modification of Cotton Fabric Biomolecules doi: 10.3390/biom10020220 Authors: Ling Guo Zhi-Yi Yang Ren-Cheng Tang Hua-Bin Yuan Cotton has the shortcomings of having no antibacterial, antioxidant and ultraviolet (UV) protection properties, which are of great importance for health protection purposes. In the present study, grape seed extract (GSE) mainly...
Sun Feb 02, 2020 02:00
Biomolecules, Vol. 10, Pages 217: Intracellular Delivery of DNA and Protein by a Novel Cell-Permeable Peptide Derived from DOT1L Biomolecules doi: 10.3390/biom10020217 Authors: Jingping Geng Xiangli Guo Lidan Wang Richard Q. Nguyen Fengqin Wang Changbai Liu Hu Wang Cellular uptake and intracellular release efficiency of biomacromolecules is low because of hurdles in the cell membrane that result in limited access to intra-cellular targets with few functional effects....
Sun Feb 02, 2020 02:00
Biomolecules, Vol. 10, Pages 218: Efficacy of Jackfruit365™ Green Jackfruit Flour Fortified Diet on Pegfilgrastim to Prevent Chemotherapy-Induced Leukopenia, Irrespective of Tumor Type or Drugs Used—A Retrospective Study Biomolecules doi: 10.3390/biom10020218 Authors: Thomas Varughese James Joseph Rejeesh Menon Chemotherapy-Induced Leukopenia (CIL) is associated with increased mortality and economic burden on patients. This study was conducted to evaluate whether inclusion of green...
Sun Feb 02, 2020 02:00
Biomolecules, Vol. 10, Pages 216: hNGF Peptides Elicit the NGF-TrkA Signalling Pathway in Cholinergic Neurons and Retain Full Neurotrophic Activity in the DRG Assay Biomolecules doi: 10.3390/biom10020216 Authors: Triaca Fico Sposato Caioli Ciotti Zona Mercanti La Mendola Satriano Rizzarelli Tirassa Calissano In the last decade, Nerve Growth Factor (NGF)-based clinical approaches have lacked specific and efficient Tyrosine Kinase A (TrkA) agonists...
Sat Feb 01, 2020 02:00
Biomolecules, Vol. 10, Pages 215: Microwave-Assisted versus Conventional Isolation of Glucosinolate Degradation Products from Lunaria annua L. and Their Cytotoxic Activity Biomolecules doi: 10.3390/biom10020215 Authors: Ivica Blažević Azra Đulović Vedrana Čikeš Čulić Marijana Popović Xavier Guillot Franko Burčul Patrick Rollin Glucosinolates (GSLs) from Lunaria annua L. seeds were analyzed qualitatively and quantitatively by their desulfo counterparts using UHPLC-DAD-MS/MS...
Sat Feb 01, 2020 02:00
Biomolecules, Vol. 10, Pages 214: Structural Changes of Sarco/Endoplasmic Reticulum Ca2+-ATPase Induced by Rutin Arachidonate: A Molecular Dynamics Study Biomolecules doi: 10.3390/biom10020214 Authors: Rodríguez Májeková Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) maintains the level of calcium concentration in cells by pumping calcium ions from the cytoplasm to the lumen while undergoing substantial conformational changes, which can be stabilized or prevented by various compounds....
Sat Feb 01, 2020 02:00
Biomolecules, Vol. 10, Pages 213: Spraying Ozonated Water on Bobal Grapevines: Effect on Wine Quality Biomolecules doi: 10.3390/biom10020213 Authors: Ana Campayo Kortes Serrano de la Hoz M. Mercedes García-Martínez M. Rosario Salinas Gonzalo L. Alonso Ozonated water is being introduced as an alternative phytosanitary treatment to control grapevine diseases in a context in which the reduction of chemical pesticides has become an urgent necessity. In this study, we evaluated...
Sat Feb 01, 2020 02:00
Biomolecules, Vol. 10, Pages 212: Hippocampal CCR5/RANTES Elevations in a Rodent Model of Post-Traumatic Stress Disorder: Maraviroc (a CCR5 Antagonist) Increases Corticosterone Levels and Enhances Fear Memory Consolidation Biomolecules doi: 10.3390/biom10020212 Authors: Merino Muñetón-Gomez Muñetón-Gómez Pérez-Izquierdo Loscertales Toledano Gasca Background: Contextual fear conditioning (CFC) is a rodent model that induces a high and long-lasting level of conditioning...
Sat Feb 01, 2020 02:00
Biomolecules, Vol. 10, Pages 211: Mechanisms and Alterations of Cardiac Ion Channels Leading to Disease: Role of Ankyrin-B in Cardiac Function Biomolecules doi: 10.3390/biom10020211 Authors: Holly C. Sucharski Emma K. Dudley Caullin B.R. Keith Mona El Refaey Sara N. Koenig Peter J. Mohler Ankyrin-B (encoded by ANK2), originally identified as a key cytoskeletal-associated protein in the brain, is highly expressed in the heart and plays critical roles in cardiac physiology...
Fri Jan 31, 2020 02:00
Biomolecules, Vol. 10, Pages 209: Cynara cardunculus Crude Extract as a Powerful Natural Herbicide and Insight into the Mode of Action of Its Bioactive Molecules Biomolecules doi: 10.3390/biom10020209 Authors: Ben Kaab Lins Hanafi Bettaieb Rebey Deleu Fauconnier Ksouri Jijakli Clerck The use of chemical herbicides could not only potentially induce negative impacts on the environment, animals, and human health, but also increase the weed resistance to...
Fri Jan 31, 2020 02:00
Biomolecules, Vol. 10, Pages 210: Pharmacological Inhibition of Caspase-8 Suppresses Inflammation-Induced Angiogenesis in the Cornea Biomolecules doi: 10.3390/biom10020210 Authors: Tian Li Liu Xie Huang Li Li Pan Chen Su Inflammation-induced angiogenesis is closely related to many diseases and has been regarded as a therapeutic target. Caspase-8 has attracted increasing attention for its immune properties and therapeutic potential in inflammatory...
Fri Jan 31, 2020 02:00
Biomolecules, Vol. 10, Pages 208: A Genetic Polymorphism in the Pannexin1 Gene Predisposes for The Development of Endothelial Dysfunction with Increasing BMI Biomolecules doi: 10.3390/biom10020208 Authors: Molica Quercioli Montecucco Schindler Kwak Morel Endothelial dysfunction worsens when body mass index (BMI) increases. Pannexin1 (Panx1) ATP release channels regulate endothelial function and lipid homeostasis in mice. We investigated whether the Panx1-400A>C...
Fri Jan 31, 2020 02:00
Biomolecules, Vol. 10, Pages 207: Quercetin and Coumarin Inhibit Dipeptidyl Peptidase-IV and Exhibits Antioxidant Properties: In Silico, In Vitro, Ex Vivo Biomolecules doi: 10.3390/biom10020207 Authors: Singh Patel Choudhary Joshi Yadav Jin Quercetin and coumarin, two naturally occurring phytochemicals of plant origin, are known to regulate hyperglycemia and oxidative stress. The present study was designed to evaluate the inhibitory activity of quercetin and coumarin...
Fri Jan 31, 2020 02:00
Biomolecules, Vol. 10, Pages 206: Assessment of Fatty Acid Desaturase (Fads2) Structure-Function Properties in Fish in the Context of Environmental Adaptations and as a Target for Genetic Engineering Biomolecules doi: 10.3390/biom10020206 Authors: Bláhová Harvey Pšenička Mráz Fatty acid desaturase 2 (Fads2) is the key enzyme of long-chain polyunsaturated fatty acid (LC-PUFA) biosynthesis. Endogenous production of these biomolecules in vertebrates, if present, is insufficient...
Fri Jan 31, 2020 02:00
Biosensors, Vol. 10, Pages 9: Screen-Printed Electrodes Modified with Metal Nanoparticles for Small Molecule Sensing Biosensors doi: 10.3390/bios10020009 Authors: Daniel Antuña-Jiménez María Begoña González-García David Hernández-Santos Pablo Fanjul-Bolado Recent progress in the field of electroanalysis with metal nanoparticle (NP)-based screen-printed electrodes (SPEs) is discussed, focusing on the methods employed to perform the electrode surface functionalization, and the...
Sat Feb 01, 2020 02:00
Brain Sciences, Vol. 10, Pages 80: Balance Training with Electromyogram-Triggered Functional Electrical Stimulation in the Rehabilitation of Stroke Patients Brain Sciences doi: 10.3390/brainsci10020080 Authors: Kyeongjin Lee This study was conducted to investigate the effects of balance training with electromyogram-triggered functional electrical stimulation (EMG-triggered FES) to improve static balance, dynamic balance, and ankle muscle activation in stroke patients. Forty-nine participants...
Sun Feb 02, 2020 02:00
Brain Sciences, Vol. 10, Pages 79: Behavioral and Electrophysiological Correlates of Performance Monitoring and Development in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder Brain Sciences doi: 10.3390/brainsci10020079 Authors: Yanni Liu Gregory L. Hanna Barbara S. Hanna Haley E. Rough Paul D. Arnold William J. Gehring The pathophysiology of attention-deficit/hyperactivity disorder (ADHD) involves deficits in performance monitoring and adaptive...
Sun Feb 02, 2020 02:00
Brain Sciences, Vol. 10, Pages 78: Progression of Neuropsychiatric Symptoms over Time in an Incident Parkinson’s Disease Cohort (ICICLE-PD) Brain Sciences doi: 10.3390/brainsci10020078 Authors: J. K. Dlay G. W. Duncan T. K. Khoo C. H. Williams-Gray D. P. Breen R. A. Barker D. J. Burn R. A. Lawson A. J. Yarnall Background: Cross-sectional studies have identified that the prevalence of neuropsychiatric symptoms (NPS) in Parkinson’s disease (PD) ranges...
Sun Feb 02, 2020 02:00
Brain Sciences, Vol. 10, Pages 77: Development and Evaluation of a Screening Tool to Aid the Diagnosis of a Cluster Headache Brain Sciences doi: 10.3390/brainsci10020077 Authors: Buture Boland Dikomitis Huang Ahmed Cluster headache (CH), a severe primary headache, is often misdiagnosed and mismanaged. The aim of this study was to develop and evaluate a screening tool to aid the diagnosis of CH. We developed a novel 12-item screening tool. This was comprised of four components:...
Sat Feb 01, 2020 02:00
Brain Sciences, Vol. 10, Pages 76: Flanker Task Performance in Isolated Dystonia (Blepharospasm): A Focus on Sequential Effects Brain Sciences doi: 10.3390/brainsci10020076 Authors: Max Pekrul Caroline Seer Florian Lange Dirk Dressler Bruno Kopp Isolated dystonia manifests with involuntary muscle hyperactivity, but the extent of cognitive impairment remains controversial. We examined the executive functions in blepharospasm while accounting for motor symptom-related distractions...
Sat Feb 01, 2020 02:00
Brain Sciences, Vol. 10, Pages 75: Using Light for Therapy of Glioblastoma Multiforme (GBM) Brain Sciences doi: 10.3390/brainsci10020075 Authors: Vasilev Sofi Rahman Smith Teschemacher Kasparov : Glioblastoma multiforme (GBM) is the most malignant form of primary brain tumour with extremely poor prognosis. The current standard of care for newly diagnosed GBM includes maximal surgical resection followed by radiotherapy and adjuvant chemotherapy. The introduction of...
Fri Jan 31, 2020 02:00
Brain Sciences, Vol. 10, Pages 74: Validity and Reliability of a Test Battery to Assess Change of Directions with Ball Dribbling in Para-footballers with Cerebral Palsy Brain Sciences doi: 10.3390/brainsci10020074 Authors: Daniel Reina Gorla Bastos Roldan The purpose of this study was to evaluate the content and construct validity and between-sessions reliability of four agility tests requiring ball dribbling in football players with cerebral palsy (CP) with implications...
Fri Jan 31, 2020 02:00
Cancers, Vol. 12, Pages 336: C20orf27 Promotes Cell Growth and Proliferation of Colorectal Cancer via the TGFβR-TAK1-NFĸB Pathway Cancers doi: 10.3390/cancers12020336 Authors: Jing Gao Yang Wang Weixia Zhang Jing Zhang Shaohua Lu Kun Meng Xingfeng Yin Zhenghua Sun Qing-Yu He Background: Colorectal cancer (CRC) is a high incidence of malignant tumors that lacks highly effective and targeted drugs and thus it is in urgent need of finding new specific molecular targets....
Sun Feb 02, 2020 02:00
Cancers, Vol. 12, Pages 335: Sensitive Photodynamic Detection of Adult T-cell Leukemia/Lymphoma and Specific Leukemic Cell Death Induced by Photodynamic Therapy: Current Status in Hematopoietic Malignancies Cancers doi: 10.3390/cancers12020335 Authors: Oka Matsuoka Utsunomiya Adult T-cell leukemia/lymphoma (ATL), an aggressive type of T-cell malignancy, is caused by the human T-cell leukemia virus type I (HTLV-1) infections. The outcomes, following therapeutic interventions...
Sun Feb 02, 2020 02:00
Cancers, Vol. 12, Pages 333: The Unfolded Protein Response: A Novel Therapeutic Target in Acute Leukemias Cancers doi: 10.3390/cancers12020333 Authors: Alberto M. Martelli Francesca Paganelli Francesca Chiarini Camilla Evangelisti James A. McCubrey The unfolded protein response (UPR) is an evolutionarily conserved adaptive response triggered by the stress of the endoplasmic reticulum (ER) due, among other causes, to altered cell protein homeostasis (proteostasis). UPR is...
Sat Feb 01, 2020 02:00
Cancers, Vol. 12, Pages 332: Regorafenib Alteration of the BCL-xL/MCL-1 Ratio Provides a Therapeutic Opportunity for BH3-Mimetics in Hepatocellular Carcinoma Models Cancers doi: 10.3390/cancers12020332 Authors: Blanca Cucarull Anna Tutusaus Miguel Subías Milica Stefanovic Tania Hernáez-Alsina Loreto Boix María Reig Pablo García de Frutos Montserrat Marí Anna Colell Jordi Bruix Albert Morales Background: The multikinase inhibitor regorafenib, approved...
Sat Feb 01, 2020 02:00
Cancers, Vol. 12, Pages 331: Ipilimumab and Its Derived EGFR Aptamer-Based Conjugate Induce Efficient NK Cell Activation against Cancer Cells Cancers doi: 10.3390/cancers12020331 Authors: Passariello Camorani Vetrei Ricci Cerchia De Lorenzo The immune checkpoint CTLA-4 (cytotoxic T-lymphocyte-antigen 4), which inhibits the co-stimulatory CD28 signal on T cells, has been recently found expressed on other cell populations, such as tumor and natural killer (NK) cells....
Sat Feb 01, 2020 02:00
Cancers, Vol. 12, Pages 329: Nicotine Induces IL-8 Secretion from Pancreatic Cancer Stroma and Worsens Cancer-Induced Cachexia Cancers doi: 10.3390/cancers12020329 Authors: Patrick W. Underwood Dong Yu Zhang Miles E. Cameron Michael H. Gerber Daniel Delitto Michael U. Maduka Kyle J. Cooper Song Han Steven J. Hughes Sarah M. Judge Andrew R. Judge Jose G. Trevino Smoking is highly associated with pancreatic cancer. Nicotine, the addictive component of tobacco,...
Sat Feb 01, 2020 02:00
Cancers, Vol. 12, Pages 330: Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome Cancers doi: 10.3390/cancers12020330 Authors: Labots Pham Honeywell Knol Beekhof de Goeij-de Haas Dekker Neerincx Piersma van der Mijn van der Peet Meijerink Peters van Grieken Jiménez Verheul Identification of predictive biomarkers for targeted...
Sat Feb 01, 2020 02:00
Cancers, Vol. 12, Pages 328: Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disorders after Hematopoietic Stem Cell Transplantation: Pathogenesis, Risk Factors and Clinical Outcomes Cancers doi: 10.3390/cancers12020328 Authors: Fujimoto Suzuki Epstein-Barr virus (EBV) is a ubiquitous virus belonging to the human -herpes virus subfamily. After primary infection, EBV maintains a life-long latent infection. A major concern is that EBV can cause a diverse range of...
Sat Feb 01, 2020 02:00
Cancers, Vol. 12, Pages 327: Treatment with Beta-Blockers and ACE-Inhibitors in Breast Cancer Patients Receiving Adjuvant Trastuzumab-Based Therapy and Developing Mild Cardiac Toxicity: A Prospective Study Cancers doi: 10.3390/cancers12020327 Authors: Geuna Lombardi Martinello Garino Bonzano Galizia Nuzzo Berchialla Becco Mangioni Zarlo Montemurro Background: Angiotensin Converting Enzyme inhibitors (ACEis) and beta-blockers (BB) are suggested...
Fri Jan 31, 2020 02:00
Cancers, Vol. 12, Pages 326: GP130 Cytokines in Breast Cancer and Bone Cancers doi: 10.3390/cancers12020326 Authors: Tolu Omokehinde Rachelle W. Johnson Breast cancer cells have a high predilection for skeletal homing, where they may either induce osteolytic bone destruction or enter a latency period in which they remain quiescent. Breast cancer cells produce and encounter autocrine and paracrine cytokine signals in the bone microenvironment, which can influence their behavior in...
Fri Jan 31, 2020 02:00
Cancers, Vol. 12, Pages 325: Mutation Analysis of Colorectal and Gastric Carcinomas Originating from Adenomas: Insights into Genomic Evolution Associated with Malignant Progression Cancers doi: 10.3390/cancers12020325 Authors: Lee Yoo Song Lim Kim Small malignant tumor foci arising from benign lesions are rare but offer a unique opportunity to investigate the genomic evolution that occurs during malignant transformation. In this study, we analyzed 11 colorectal and 10...
Fri Jan 31, 2020 02:00
Cells, Vol. 9, Pages 345: New Insight into Plant Signaling: Extracellular ATP and Uncommon Nucleotides Cells doi: 10.3390/cells9020345 Authors: Pietrowska-Borek Dobrogojski Sobieszczuk-Nowicka Borek New players in plant signaling are described in detail in this review: extracellular ATP (eATP) and uncommon nucleotides such as dinucleoside polyphosphates (NpnN’s), adenosine 5′-phosphoramidate (NH2-pA), and extracellular NAD+ and NADP+ (eNAD(P)+). Recent...
Sun Feb 02, 2020 02:00
Cells, Vol. 9, Pages 344: An Automated, Single Cell Quantitative Imaging Microscopy Approach to Assess Micronucleus Formation, Genotoxicity and Chromosome Instability Cells doi: 10.3390/cells9020344 Authors: Chloe C. Lepage Laura L. Thompson Bradley Larson Kirk J. McManus Micronuclei are small, extranuclear bodies that are distinct from the primary cell nucleus. Micronucleus formation is an aberrant event that suggests a history of genotoxic stress or chromosome mis-segregation...
Sun Feb 02, 2020 02:00
Cells, Vol. 9, Pages 343: PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273 Cells doi: 10.3390/cells9020343 Authors: Keon Woo Khim Sun Sil Choi Hyun-Jun Jang Yo Han Lee Eujin Lee Ji-Min Hyun Hye-Jin Eom Sora Yoon Jeong-Won Choi Tae-Eun Park Dougu Nam Jang Hyun Choi Peroxisome proliferator-activated receptor γ (PPARγ) is a master regulator of adipose tissue biology. In obesity, phosphorylation...
Sun Feb 02, 2020 02:00
Cells, Vol. 9, Pages 340: Fatty Acid Oxidation and Mitochondrial Morphology Changes as Key Modulators of the Affinity for ADP in Rat Heart Mitochondria Cells doi: 10.3390/cells9020340 Authors: Adolfas Toleikis Sonata Trumbeckaite Julius Liobikas Neringa Pauziene Lolita Kursvietiene Dalia M. Kopustinskiene Fatty acids are the main respiratory substrates important for cardiac function, and their oxidation is altered during various chronic disorders. We investigated the mechanism...
Sat Feb 01, 2020 02:00
Cells, Vol. 9, Pages 341: Metabolomic Analysis of the Liver of a Dextran Sodium Sulfate-Induced Acute Colitis Mouse Model: Implications of the Gut–Liver Connection Cells doi: 10.3390/cells9020341 Authors: Sou Hyun Kim Wonho Lee Doyoung Kwon Seunghyun Lee Seung Won Son Min-Soo Seo Kil Soo Kim Yun-Hee Lee Suhkmann Kim Young-Suk Jung The incidence of ulcerative colitis (UC) is increasing worldwide, and it has become a growing problem in Asia. Previous research...
Sat Feb 01, 2020 02:00
Cells, Vol. 9, Pages 339: Three-dimensional Organization of Polytene Chromosomes in Somatic and Germline Tissues of Malaria Mosquitoes Cells doi: 10.3390/cells9020339 Authors: Phillip George Nicholas A. Kinney Jiangtao Liang Alexey V. Onufriev Igor V. Sharakhov Spatial organization of chromosome territories and interactions between interphase chromosomes themselves, as well as with the nuclear periphery, play important roles in epigenetic regulation of the genome function....
Sat Feb 01, 2020 02:00
Cells, Vol. 9, Pages 342: Loading of Primary Human T Lymphocytes with Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Does Not Impair Their Activation after Polyclonal Stimulation Cells doi: 10.3390/cells9020342 Authors: Marina Mühlberger Harald Unterweger Julia Band Christian Lehmann Lukas Heger Diana Dudziak Christoph Alexiou Geoffrey Lee Christina Janko For the conversion of immunologically cold tumors, characterized by a low T cell infiltration,...
Sat Feb 01, 2020 02:00
Cells, Vol. 9, Pages 338: Mitophagy in Acute Kidney Injury and Kidney Repair Cells doi: 10.3390/cells9020338 Authors: Ying Wang Juan Cai Chengyuan Tang Zheng Dong Acute kidney injury (AKI) is a major kidney disease characterized by rapid decline of renal function. Besides its acute consequence of high mortality, AKI has recently been recognized as an independent risk factor for chronic kidney disease (CKD). Maladaptive or incomplete repair of renal tubules after severe or episodic...
Sat Feb 01, 2020 02:00
Cells, Vol. 9, Pages 337: Sphingosine-1-Phosphate in the Tumor Microenvironment: A Signaling Hub Regulating Cancer Hallmarks Cells doi: 10.3390/cells9020337 Authors: Laura Riboni Loubna Abdel Hadi Stefania Elena Navone Laura Guarnaccia Rolando Campanella Giovanni Marfia As a key hub of malignant properties, the cancer microenvironment plays a crucial role intimately connected to tumor properties. Accumulating evidence supports that the lysophospholipid sphingosine-1-phosphate...
Sat Feb 01, 2020 02:00
Cells, Vol. 9, Pages 336: Prolonged Hyperoxygenation Treatment Improves Vein Graft Patency and Decreases Macrophage Content in Atherosclerotic Lesions in ApoE3*Leiden Mice Cells doi: 10.3390/cells9020336 Authors: Parma Peters Baganha Sluimer Vries Quax Unstable atherosclerotic plaques frequently show plaque angiogenesis which increases the chance of rupture and thrombus formation leading to infarctions. Hypoxia plays a role in angiogenesis and inflammation, two...
Sat Feb 01, 2020 02:00
Cells, Vol. 9, Pages 335: Vitamin D and Ovarian Cancer: Systematic Review of the Literature with a Focus on Molecular Mechanisms Cells doi: 10.3390/cells9020335 Authors: Dovnik Dovnik Vitamin D is a lipid soluble vitamin involved primarily in calcium metabolism. Epidemiologic evidence indicates that lower circulating vitamin D levels are associated with a higher risk of ovarian cancer and that vitamin D supplementation is associated with decreased cancer mortality. A vast amount...
Sat Feb 01, 2020 02:00
Cells, Vol. 9, Pages 334: Living with Yourself: Innate Lymphoid Cell Immunometabolism Cells doi: 10.3390/cells9020334 Authors: Rolot O’Sullivan Innate lymphoid cells (ILCs) are tissue-resident sentinels of the immune system that function to protect local tissue microenvironments against pathogens and maintain homeostasis. However, because ILCs are sensitively tuned to perturbations within tissues, they can also contribute to host pathology when critical activating signals become...
Sat Feb 01, 2020 02:00
Cells, Vol. 9, Pages 333: Exercise-Induced Vascular Adaptations under Artificially Versus Pathologically Reduced Blood Flow: A Focus Review with Special Emphasis on Arteriogenesis Cells doi: 10.3390/cells9020333 Authors: Vogel Niederer Jung Troidl Background: The vascular effects of training under blood flow restriction (BFR) in healthy persons can serve as a model for the exercise mechanism in lower extremity arterial disease (LEAD) patients. Both mechanisms are, inter...
Fri Jan 31, 2020 02:00
Cells, Vol. 9, Pages 332: Autophagy Controls Sulphur Metabolism in the Rosette Leaves of Arabidopsis and Facilitates S Remobilization to the Seeds Cells doi: 10.3390/cells9020332 Authors: Lornac Havé Chardon Soulay Clément Avice Masclaux-Daubresse Sulphur deficiency in crops became an agricultural concern several decades ago, due to the decrease of S deposition and the atmospheric sulphur dioxide emissions released by industrial plants. Autophagy, which is a...
Fri Jan 31, 2020 02:00
Cells, Vol. 9, Pages 331: A Potential Nutraceutical Candidate Lactucin Inhibits Adipogenesis through Downregulation of JAK2/STAT3 Signaling Pathway-Mediated Mitotic Clonal Expansion Cells doi: 10.3390/cells9020331 Authors: Xin Wang Min Liu Guo He Cai Yan Chen Xiao Chen Shi Cong Cong Zhang Bo Xia Bao Cai Xie Huan Liu Rui Xin Zhang Jun Feng Lu Meng Qing Zhu Shi Zhen Yang Xin Yi Chu Dan Yang Zhang Yong Liang Wang Jiang Wei Wu The prevalence...
Fri Jan 31, 2020 02:00
Cells, Vol. 9, Pages 328: Poison-Exon Inclusion in DHX9 Reduces Its Expression and Sensitizes Ewing Sarcoma Cells to Chemotherapeutic Treatment Cells doi: 10.3390/cells9020328 Authors: Palombo Verdile Paronetto Alternative splicing is a combinatorial mechanism by which exons are joined to produce multiple mRNA variants, thus expanding the coding potential and plasticity of eukaryotic genomes. Defects in alternative splicing regulation are associated with several human diseases,...
Fri Jan 31, 2020 02:00
Cells, Vol. 9, Pages 329: Mouse Embryonic Stem Cell-Derived Ureteric Bud Progenitors Induce Nephrogenesis Cells doi: 10.3390/cells9020329 Authors: Tan Rak-Raszewska Skovorodkin Vainio Generation of kidney organoids from pluripotent stem cells (PSCs) is regarded as a potentially powerful way to study kidney development, disease, and regeneration. Direct differentiation of PSCs towards renal lineages is well studied; however, most of the studies relate to generation of nephron...
Fri Jan 31, 2020 02:00
Cells, Vol. 9, Pages 330: Interleukin-6 Derived from the Central Nervous System May Influence the Pathogenesis of Experimental Autoimmune Encephalomyelitis in a Cell-Dependent Manner Cells doi: 10.3390/cells9020330 Authors: Sanchis Fernández-Gayol Comes Escrig Giralt Palmiter Hidalgo Background: Interleukin-6 (IL-6) is a pleiotropic and multifunctional cytokine that plays a critical role in induction of experimental autoimmune encephalomyelitis (EAE), a mouse...
Fri Jan 31, 2020 02:00
Children, Vol. 7, Pages 11: Advances in Pediatric Acute Promyelocytic Leukemia Children doi: 10.3390/children7020011 Authors: Shannon E. Conneely Alexandra M. Stevens Acute promyelocytic leukemia (APL) is a rare disease accounting for only 5%–10% of pediatric acute myeloid leukemia (AML) and fewer than 1000 cases occur annually in the United States across all age groups. Characterized by t (15; 17), with a resultant PML-RARA gene fusion driving leukemia development, advances...
Sun Feb 02, 2020 02:00
Children, Vol. 7, Pages 10: Hypovitaminosis D and Cardiometabolic Risk Factors in Adolescents with Severe Obesity Children doi: 10.3390/children7020010 Authors: Teodoro Durá-Travé Fidel Gallinas-Victoriano Diego Mauricio Peñafiel-Freire María Urretavizcaya-Martinez Paula Moreno-González María Jesús Chueca-Guindulain Background/Objectives. Obesity is associated with cardiometabolic risk factors and with Vitamin D deficiency. The aim of this study was to examine the relationship...
Sat Feb 01, 2020 02:00
Climate, Vol. 8, Pages 24: Prospects for Erratic and Intensifying Madden-Julian Oscillations Climate doi: 10.3390/cli8020024 Authors: Patrick Haertel The Madden–Julian Oscillation (MJO) is a planetary-scale convective disturbance that typically forms in the equatorial Indian Ocean, propagates slowly eastward, and dissipates near the date line. This study examines how the MJO changes in response to a changing radiative forcing in a fully-Lagrangian coupled model (LCM) that is...
Sun Feb 02, 2020 02:00
Dentistry Journal, Vol. 8, Pages 14: Virtual Implant Rehabilitation of the Severely Atrophic Maxilla: A Radiographic Study Dentistry Journal doi: 10.3390/dj8010014 Authors: Michele Manacorda Bianca Poletti de Chaurand Alberto Merlone Giulia Tetè Francesca Mottola Raffaele Vinci Background: Advanced maxillary atrophy is one of the most common clinical scenarios where implant placement could become difficult. Nevertheless, a volumetric evaluation using a suitable diagnostic...
Sun Feb 02, 2020 02:00
Diagnostics, Vol. 10, Pages 80: Concurrent Validity and Reliability of an Inertial Measurement Unit for the Assessment of Craniocervical Range of Motion in Subjects with Cerebral Palsy Diagnostics doi: 10.3390/diagnostics10020080 Authors: Cristina Carmona-Pérez Juan Luis Garrido-Castro Francisco Torres Vidal Sandra Alcaraz-Clariana Lourdes García-Luque Francisco Alburquerque-Sendín Daiana Priscila Rodrigues-de-Souza Objective: This study aimed to determine the validity...
Sat Feb 01, 2020 02:00
Diagnostics, Vol. 10, Pages 81: Assessment of the Impact of Rapid Point-of-Care CD4 Testing in Primary Healthcare Clinic Settings: A Survey Study of Client and Provider Perspectives Diagnostics doi: 10.3390/diagnostics10020081 Authors: Shabashini Reddy Andrew Gibbs Elizabeth Spooner Noluthando Ngomane Tarylee Reddy Nozipho |Luthuli Gita Ramjee Anna Coutsoudis Photini Kiepiela Background: The high burden of disease in South Africa presents challenges to public...
Sat Feb 01, 2020 02:00
Diagnostics, Vol. 10, Pages 78: Predicting Clinical Efficacy of Vascular Disrupting Agents in Rodent Models of Primary and Secondary Liver Cancers: An Overview with Imaging-Histopathology Correlation Diagnostics doi: 10.3390/diagnostics10020078 Authors: Yewei Liu Shuncong Wang Xiaohui Zhao Yuanbo Feng Guy Bormans Johan Swinnen Raymond Oyen Gang Huang Yicheng Ni Yue Li Vascular disrupting agents (VDAs) have entered clinical trials for over 15 years. As the leading...
Fri Jan 31, 2020 02:00
Diagnostics, Vol. 10, Pages 77: Ovarian Seromucinous Tumors: Pathogenesis, Morphologic Spectrum, and Clinical Issues Diagnostics doi: 10.3390/diagnostics10020077 Authors: Nagamine Mikami Ovarian seromucinous tumors were introduced in the 2014 World Health Organization (WHO) classification as one of the seven types of ovarian epithelial tumors. They are characterized by frequent association with endometriosis and bilaterality, microscopic appearance of papillary architecture, and...
Fri Jan 31, 2020 02:00
Diagnostics, Vol. 10, Pages 79: Assessment of Renal Osteodystrophy via Computational Analysis of Label-free Raman Detection of Multiple Biomarkers Diagnostics doi: 10.3390/diagnostics10020079 Authors: Marian Manciu Mario Cardenas Kevin E. Bennet Avudaiappan Maran Michael J. Yaszemski Theresa A. Maldonado Diana Magiricu Felicia S. Manciu Accurate clinical evaluation of renal osteodystrophy (ROD) is currently accomplished using invasive in vivo transiliac bone biopsy,...
Fri Jan 31, 2020 02:00
Diagnostics, Vol. 10, Pages 76: The Roles of Celiac Trunk Angle and Vertebral Origin in Median Arcuate Ligament Syndrome Diagnostics doi: 10.3390/diagnostics10020076 Authors: Ryan P. Dyches Kelsey J. Eaton Heather F. Smith Median arcuate ligament syndrome (MALS) is a rarely diagnosed condition resulting from compression of the celiac trunk (CT) by the median arcuate ligament (MAL) of the diaphragm. Ischemia due to reduced blood flow through the CT and/or neuropathic pain resulting...
Fri Jan 31, 2020 02:00
Diversity, Vol. 12, Pages 59: Feeding Specialization of Honey Badgers in the Sahara Desert: A Trial of Life in a Hard Environment Diversity doi: 10.3390/d12020059 Authors: Gil-Sánchez Herrera-Sánchez Rodríguez-Siles Sáez Díaz-Portero Arredondo Álvarez Cancio Lucas Castillo McCain Pérez Valenzuela Valderrama Bautista Sarabia Leonard Sánchez-Cerdá Virgós Qninba : The honey badger (Mellivora capensis) is a medium-sized...
Sun Feb 02, 2020 02:00
Diversity, Vol. 12, Pages 58: An Italian Research Culture Collection of Wood Decay Fungi Diversity doi: 10.3390/d12020058 Authors: Girometta Bernicchia Baiguera Bracco Buratti Cartabia Picco Savino One of the main aims of the University of Pavia mycology laboratory was to collect wood decay fungal (WDF) strains in order to deepen taxonomic studies, species distribution, officinal properties or to investigate potential applications such as biocomposite material...
Sat Feb 01, 2020 02:00
Diversity, Vol. 12, Pages 57: Structure, Diversity, and Composition of Bacterial Communities in Rhizospheric Soil of Coptis chinensis Franch under Continuously Cropped Fields Diversity doi: 10.3390/d12020057 Authors: Mohammad Murtaza Alami Jinqi Xue Yutao Ma Dengyan Zhu Zedan Gong Shaohua Shu Xuekui Wang Soil microorganisms are critical factors of plant productivity in terrestrial ecosystems. Coptis chinensis Franch is one of the most important medicinal plants in China....
Sat Feb 01, 2020 02:00
Diversity, Vol. 12, Pages 56: Can Topographic Variation in Climate Buffer against Climate Change-Induced Population Declines in Northern Forest Birds? Diversity doi: 10.3390/d12020056 Authors: Raimo Virkkala Juha Aalto Risto K. Heikkinen Ari Rajasärkkä Saija Kuusela Niko Leikola Miska Luoto Increased attention is being paid to the ecological drivers and conservation measures which could mitigate climate change-induced pressures for species survival, potentially helping...
Sat Feb 01, 2020 02:00
Epigenomes, Vol. 4, Pages 1: Epigenetics of Skeletal Muscle-Associated Genes in the ASB, LRRC, TMEM, and OSBPL Gene Families Epigenomes doi: 10.3390/epigenomes4010001 Authors: Ehrlich Lacey Ehrlich Much remains to be discovered about the intersection of tissue-specific transcription control and the epigenetics of skeletal muscle (SkM), a very complex and dynamic organ. From four gene families, Leucine-Rich Repeat Containing (LRRC), Oxysterol Binding Protein Like (OSBPL), Ankyrin...
Thu Jan 30, 2020 02:00
Fermentation, Vol. 6, Pages 19: Cheese Whey Fermentation by Its Native Microbiota: Proteolysis and Bioactive Peptides Release with ACE-Inhibitory Activity Fermentation doi: 10.3390/fermentation6010019 Authors: Miguel A. Mazorra-Manzano Glen R. Robles-Porchas Daniel A. González-Velázquez María J. Torres-Llanez Marcel Martínez-Porchas Celia O. García-Sifuentes Aarón F. González-Córdova Belinda Vallejo-Córdoba Cheese whey contains about 20% of the total milk protein...
Fri Jan 31, 2020 02:00
Foods, Vol. 9, Pages 147: Do French Consumers Have the Same Social Representations of Pulses as Food Industry Professionals? Foods doi: 10.3390/foods9020147 Authors: Juliana Melendrez-Ruiz Gaëlle Arvisenet Vincent Laugel Stéphanie Chambaron Sandrine Monnery-Patris Pulses present many advantages for human health, nutrition, sustainability, and the environment. Despite efforts in recent years by the pulse industry and national authorities to favor pulses, consumption in France...
Sat Feb 01, 2020 02:00
Foods, Vol. 9, Pages 145: Optimization of the Formula and Processing Factors for Gluten-Free Rice Bread with Tamarind Gum Foods doi: 10.3390/foods9020145 Authors: Hong Kweon The formula and processing parameters for gluten-free rice bread were optimized using a factorial design, including a center point. Gum concentration (GC), water amount (WA), mixing time (MT), and fermentation time (FT) were selected as factors, and two levels were used for each factor: 1 and 2% for GC; 80 and...
Sat Feb 01, 2020 02:00
Foods, Vol. 9, Pages 146: Individual Differences in Sweetness Ratings and Cross-Modal Aroma-Taste Interactions Foods doi: 10.3390/foods9020146 Authors: Bertelsen Mielby Alexi Byrne Kidmose Aroma-taste interactions, which are believed to occur due to previous coexposure (concurrent presence of aroma and taste), have been suggested as a strategy to aid sugar reduction in food and beverages. However, coexposures might be influenced by individual differences. We therefore...
Sat Feb 01, 2020 02:00
Foods, Vol. 9, Pages 144: Phytochemicals of Minthostachys diffusa Epling and Their Health-Promoting Bioactivities Foods doi: 10.3390/foods9020144 Authors: Faraone Russo Chiummiento Fernandez Choudhary Monné Milella Rai The genus Minthostachys belonging to the Lamiaceae family, and is an important South American mint genus used commonly in folk medicine as an aroma in cooking. The phytochemical-rich samples of the aerial parts of Minthostachys diffusa Epling....
Sat Feb 01, 2020 02:00
Foods, Vol. 9, Pages 143: Fabricating a Pickering Stabilizer from Okara Dietary Fibre Particulates by Conjugating with Soy Protein Isolate via Maillard Reaction Foods doi: 10.3390/foods9020143 Authors: Ashaolu Zhao Okara is underutilized despite its numerous values explorable in food products. In this study, okara dietary fibre (ODF) was micronized and decorated with soy protein isolate (SPI) through a Maillard reaction by dry heating at 60 °C. The resulting ODF-SPI conjugates...
Fri Jan 31, 2020 02:00
Foods, Vol. 9, Pages 142: The Pharmacological Effects and Health Benefits of Platycodon grandiflorus—A Medicine Food Homology Species Foods doi: 10.3390/foods9020142 Authors: Ming-Yue Ji Agula Bo Min Yang Jin-Fan Xu Lin-Lin Jiang Bao-Chang Zhou Min-Hui Li Platycodon grandiflorus is a widely used edible, traditional Chinese medicinal herb. It is rich in saponins, flavonoids, phenolic acids, and other compounds. It contains a large number of fatty acids such as linoleic...
Fri Jan 31, 2020 02:00
Foods, Vol. 9, Pages 141: Comparative Evaluation of Piper nigrum, Rosmarinus officinalis, Cymbopogon citratus and Juniperus communis L. Essential Oils of Different Origin as Functional Antimicrobials in Foods Foods doi: 10.3390/foods9020141 Authors: Leja Majcher Juzwa Czaczyk Komosa Essential oils can be used as preservatives in foods because of their ability to inhibit bacteria growth in low concentration, which does not influence on foods’ organoleptic properties...
Fri Jan 31, 2020 02:00
GastrointestDisord, Vol. 2, Pages 12-26: Role of Gastric Electrical Stimulation in the Treatment of Gastroparesis Gastrointestinal Disorders doi: 10.3390/gidisord2010003 Authors: Amal Shine Thomas L. Abell Introduction: Gastric electrical stimulation (GES) is a surgically implanted treatment option for drug refractory gastroparesis syndromes. Evidence supporting use of GES and the pathophysiology of gastroparesis syndromes is not widely known. We conducted a descriptive review to...
Fri Jan 31, 2020 02:00
Healthcare, Vol. 8, Pages 28: The Impact of the Moderating Effect of Psychological Health Status on Nurse Healthcare Management Information System Usage Intention Healthcare doi: 10.3390/healthcare8010028 Authors: Shih-Jung Hsiao Hsiao-Ting Tseng Nurses play a key role in healthcare but work in a highly stressful and unfriendly environment. Therefore, many medical institutions have adopted nurse healthcare management information systems for nurses to relieve symptoms of mental stress...
Sun Feb 02, 2020 02:00
Healthcare, Vol. 8, Pages 27: Cultural Adaptation and Validation of the Portuguese Version of the CANHELP Lite Bereavement Questionnaire Healthcare doi: 10.3390/healthcare8010027 Authors: Alexandra Pereira Amélia Ferreira Ana Rita Abrantes Cristiana Gomes Joana Saraiva Laetitia Teixeira Daren K. Heyland José Martins Sara Pinto Olga Fernandes Background: Satisfaction with care is an important outcome measure in end-of-life care. Validated instruments are necessary...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 928: Effects and Mechanisms of Calcium Ion Addition on Lead Removal from Water by Eichhornia crassipes International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030928 Authors: Zhou Jiang Qin Zhang Huang Xu Karst water is rich in calcium ions (Ca2+) and exhibits poor metal availability and low biodegradation efficiency. This study sought to analyze the effects and mechanisms of Ca2+ on lead (Pb) removal and absorption...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 926: Canadian Arctic Contaminants and Their Effects on the Maternal Brain and Behaviour: A Scoping Review of the Animal Literature International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030926 Authors: Claire Fong-McMaster Sandra Konji Amanda Nitschke Anne TM Konkle Background: Environmental toxicants such as methylmercury, polychlorinated biphenyls, and organochlorine pesticides are potentially harmful pollutants present...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 927: Assess the Performance and Cost-Effectiveness of LACE and HOSPITAL Re-Admission Prediction Models as a Risk Management Tool for Home Care Patients: An Evaluation Study of a Medical Center Affiliated Home Care Unit in Taiwan International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030927 Authors: Su Wang Chen Chiu Chang Huang Hu Li Yang Wu Chen The LACE index and HOSPITAL score models are...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 925: Amateur Runners’ Commitment: An Analysis of Sociodemographic and Sports Habit Profiles International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030925 Authors: David Parra-Camacho Manuel Alonso Dos Santos María Huertas González-Serrano The aim of this work is to analyse the commitment to running among urban runners by identifying groups regarding commitment to this sport and by defining their sociodemographic profile and...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 923: Assessing Related Factors of Intention to Perpetrate Dating Violence among University Students Using the Theory of Planned Behavior International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030923 Authors: Wen-Li Hou Chung-Ying Lin Yu-Ming Wang Ying-Hua Tseng Bih-Ching Shu Dating violence (DV) is a major public health problem among youth. The majority of DV studies in Taiwan involve the assessment of DV without the...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 924: The Influence of Food Production Experience on Dietary Knowledge, Awareness, Behaviors, and Health among Japanese: A Systematic Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030924 Authors: Daisuke Machida Osamu Kushida This study aimed to reveal the influence of food production experience on dietary knowledge, dietary awareness, dietary behaviors, and health among Japanese populations. We conducted a systematic...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 922: Malay Version of Exercise Self-Efficacy: A Confirmatory Analysis among Malaysians with Type 2 Diabetes Mellitus International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030922 Authors: Aizuddin Hidrus Yee Cheng Kueh Bachok Norsa’adah Garry Kuan Exercise self-efficacy (ESE) is one of the psychological constructs in the Transtheoretical Model (TTM). The objective of the present study is to assess the validity and reliability...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 921: Evolution of Job Satisfaction and Burnout Levels of Emergency Department Professionals during a Period of Economic Recession International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030921 Authors: Aurora Fontova-Almató Rosa Suñer-Soler Laia Salleras-Duran Carme Bertran-Noguer Laura Congost-Devesa Marta Ferrer-Padrosa Dolors Juvinyà-Canal Satisfaction at work has been found to be a predictive factor of permanency....
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 920: The Association between Body Mass Index and Leisure-Time Physical Activity in Adults with Multiple Sclerosis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030920 Authors: Wi-Young So Alon Kalron (1) Purpose: Conflicting information exists regarding the relationship between obesity, leisure-time physical activity (PA), and disability in people with multiple sclerosis (PwMS). We aimed to investigate the association...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 917: Automatic Emergency Braking (AEB) System Impact on Fatality and Injury Reduction in China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030917 Authors: Hong Tan Fuquan Zhao Han Hao Zongwei Liu Amer Ahmad Amer Hassan Babiker The automatic emergency braking (AEB) system is an effective intelligent vehicle active safety system for avoiding certain types of collisions. This study develops a national-level...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 918: Users’ Modifications to Electronic Nicotine Delivery Systems (ENDS): Interviews with ENDS Enthusiasts International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030918 Authors: Yachao Li Robert T. Fairman Victoria Churchill David L. Ashley Lucy Popova Users’ modifications to electronic nicotine delivery systems (ENDS) products could increase initiation, inhibit cessation, or change the toxicity of the product....
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 916: The Impact of Environmental Information Disclosure on the Firm Value of Listed Manufacturing Firms: Evidence from China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030916 Authors: Yang Wen Li In the last decade, the public concern over environmental problems has led to the emergence of environmental regulations in firms’ information disclosure on environmental practice, especially in some developing...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 919: Ambulance Transport of Patients with Mild Conditions in Hokkaido, Japan International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030919 Authors: Hiroshi Yazaki Hiroshi Nishiura Understanding the epidemiological distributions of ambulance transport for patients with mild conditions according to age, disease, and geographic region could help in achieving optimal use of ambulance services. In the present study, we explored the...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 915: Air Pollution and Incidence of Lung Cancer by Histological Type in Korean Adults: A Korean National Health Insurance Service Health Examinee Cohort Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030915 Authors: Moon Kwon Kim Kim : Studies have reported associations between long-term exposure to ambient air pollution and lung cancer. However, there have been inconsistent reports of such associations...
Sun Feb 02, 2020 02:00
IJERPH, Vol. 17, Pages 902: Association between Malaria Infection and Early Childhood Development Mediated by Anemia in Rural Kenya International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030902 Authors: Milner Kariger Pickering Stewart Byrd Lin Rao Achando Dentz Null Fernald Malaria is a leading cause of morbidity and mortality among children under five years of age, with most cases occurring in Sub-Saharan Africa....
Sun Feb 02, 2020 02:00
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