IJMS, Vol. 21, Pages 1172: Transposon Insertion Mutagenesis in Mice for Modeling Human Cancers: Critical Insights Gained and New Opportunities International Journal of Molecular Sciences doi: 10.3390/ijms21031172 Authors: Beckmann Largaespada Transposon mutagenesis has been used to model many types of human cancer in mice, leading to the discovery of novel cancer genes and insights into the mechanism of tumorigenesis. For this review, we identified over twenty types of human cancer...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1173: An Arabidopsis Mutant Over-Expressing Subtilase SBT4.13 Uncovers the Role of Oxidative Stress in the Inhibition of Growth by Intracellular Acidification International Journal of Molecular Sciences doi: 10.3390/ijms21031173 Authors: Bissoli Muñoz-Bertomeu Bueso Sayas Vilcara Felipo Niñoles Rubio Fernández Serrano Intracellular acid stress inhibits plant growth by unknown mechanisms and it occurs in acidic soils and as consequence...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1171: Surgical Management of Spinal Disorders in People with Mucopolysaccharidoses International Journal of Molecular Sciences doi: 10.3390/ijms21031171 Authors: Hidetomi Terai Hiroaki Nakamura Mucopolysaccharidoses (MPS) are a group of inherited, multisystem, lysosomal storage disorders involving specific lysosomal enzyme deficiencies that result in the accumulation of glycosaminoglycans (GAG) secondary to insufficient degradation within cell lysosomes. GAG accumulation...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1170: BDNF as a Promising Therapeutic Agent in Parkinson’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms21031170 Authors: Ewelina Palasz Adrianna Wysocka Anna Gasiorowska Malgorzata Chalimoniuk Wiktor Niewiadomski Grazyna Niewiadomska Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration. In animal models of Parkinson’s disease (PD), BDNF enhances the survival of dopaminergic neurons,...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1168: Is Sleep Disruption a Cause or Consequence of Alzheimer’s Disease? Reviewing Its Possible Role as a Biomarker International Journal of Molecular Sciences doi: 10.3390/ijms21031168 Authors: Maria-Angeles Lloret Ana Cervera-Ferri Mariana Nepomuceno Paloma Monllor Daniel Esteve Ana Lloret In recent years, the idea that sleep is critical for cognitive processing has gained strength. Alzheimer’s disease (AD) is the most common form of dementia...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1167: Angiotensin (1-7) Decreases Myostatin-Induced NF-κB Signaling and Skeletal Muscle Atrophy International Journal of Molecular Sciences doi: 10.3390/ijms21031167 Authors: Aravena Abrigo Gonzalez Aguirre Gonzalez Simon Cabello-Verrugio Myostatin is a myokine that regulates muscle function and mass, producing muscle atrophy. Myostatin induces the degradation of myofibrillar proteins, such as myosin heavy chain or troponin. The main pathway...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1166: Quantitative Proteomics to Identify Nuclear RNA-Binding Proteins of Malat1 International Journal of Molecular Sciences doi: 10.3390/ijms21031166 Authors: Scherer Levin Butter Scheibe The long non-coding RNA Malat1 has been implicated in several human cancers, while the mechanism of action is not completely understood. As RNAs in cells function together with RNA-binding proteins (RBPs), the composition of their RBP complex can shed light on their...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1158: miR-128a Acts as a Regulator in Cardiac Development by Modulating Differentiation of Cardiac Progenitor Cell Populations International Journal of Molecular Sciences doi: 10.3390/ijms21031158 Authors: Sarah C. Hoelscher Theresia Stich Anne Diehm Harald Lahm Martina Dreßen Zhong Zhang Irina Neb Zouhair Aherrahrou Jeanette Erdmann Heribert Schunkert Gianluca Santamaria Giovanni Cuda Ralf Gilsbach Lutz Hein Rüdiger Lange David...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1169: High Dosage Lithium Treatment Induces DNA Damage and p57Kip2 Decrease International Journal of Molecular Sciences doi: 10.3390/ijms21031169 Authors: Emanuela Stampone Debora Bencivenga Clementina Barone Arianna Aulitto Federica Verace Fulvio Della Ragione Adriana Borriello Lithium salt is the first-line therapeutic option for bipolar disorder and has been proposed as a potential antitumoral drug. The effects of LiCl treatment were investigated...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1164: Kidney Inflammation, Injury and Regeneration International Journal of Molecular Sciences doi: 10.3390/ijms21031164 Authors: Baer Koch Geiger Damage to kidney cells can occur due to a variety of ischemic and toxic insults and leads to inflammation and cell death, which can result in acute kidney injury (AKI) [...]
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1163: Extracellular Vesicles Mediated Early Embryo–Maternal Interactions International Journal of Molecular Sciences doi: 10.3390/ijms21031163 Authors: Alessandra Bridi Felipe Perecin Juliano Coelho da Silveira Embryo–maternal crosstalk is an important event that involves many biological processes, which must occur perfectly for pregnancy success. This complex communication starts from the zygote stage within the oviduct and continues in the uterus...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1156: Genetic Base of Behavioral Disorders in Mucopolysaccharidoses: Transcriptomic Studies International Journal of Molecular Sciences doi: 10.3390/ijms21031156 Authors: Karolina Pierzynowska Lidia Gaffke Magdalena Podlacha Grzegorz Węgrzyn Mucopolysaccharidoses (MPS) are a group of inherited metabolic diseases caused by mutations leading to defective degradation of glycosaminoglycans (GAGs) and their accumulation in cells. Among 11 known types and subtypes...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1165: Overexpression of Tamarix hispida ThTrx5 Confers Salt Tolerance to Arabidopsis by Activating Stress Response Signals International Journal of Molecular Sciences doi: 10.3390/ijms21031165 Authors: Luan Dong Song Jiang Li Salt stress inhibits normal plant growth and development by disrupting cellular water absorption and metabolism. Therefore, understanding plant salt tolerance mechanisms should provide a theoretical basis for developing salt-resistant...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1161: High-Cholesterol Diet Decreases the Level of Phosphatidylinositol 4,5-Bisphosphate by Enhancing the Expression of Phospholipase C (PLCβ1) in Rat Brain International Journal of Molecular Sciences doi: 10.3390/ijms21031161 Authors: Chun Chung Cholesterol is a critical component of eukaryotic membranes, where it contributes to regulating transmembrane signaling, cell–cell interaction, and ion transport. Dysregulation of cholesterol levels in the...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1159: Surgical Wound Fluids from Patients with Breast Cancer Reveal Similarities in the Biological Response Induced by Intraoperative Radiation Therapy and the Radiation-Induced Bystander Effect—Transcriptomic Approach International Journal of Molecular Sciences doi: 10.3390/ijms21031159 Authors: Kulcenty Piotrowski Rucinski Wroblewska Jopek Murawa Suchorska In patients with breast cancer who undergo breast-conserving surgery (BCS), more...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1162: Speckle Tracking Echocardiography: New Ways of Translational Approaches in Preeclampsia to Detect Cardiovascular Dysfunction International Journal of Molecular Sciences doi: 10.3390/ijms21031162 Authors: Kristin Kräker Till Schütte Jamie O’Driscoll Anna Birukov Olga Patey Florian Herse Dominik N. Müller Basky Thilaganathan Nadine Haase Ralf Dechend Several studies have shown that women with a preeclamptic pregnancy exhibit an increased...
Mon Feb 10, 2020 02:00
IJMS, Vol. 21, Pages 1160: Volatile Organic Compounds from Orchids: From Synthesis and Function to Gene Regulation International Journal of Molecular Sciences doi: 10.3390/ijms21031160 Authors: Ramya Jang An Lee Park Park Orchids are one of the most significant plants that have ecologically adapted to every habitat on earth. Orchids show a high level of variation in their floral morphologies, which makes them popular as ornamental plants in the global market. Floral...
Mon Feb 10, 2020 02:00
JCM, Vol. 9, Pages 486: Nucleoside Diphosphate Kinase B Contributes to Arrhythmogenesis in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Arrhythmogenic Right Ventricular Cardiomyopathy Journal of Clinical Medicine doi: 10.3390/jcm9020486 Authors: Buljubasic El-Battrawy Lan Lomada Chatterjee Zhao Li Zhong Xu Huang Liao Lang Cyganek Zhou Wieland Borggrefe Akin Background: Arrhythmogenic right...
Mon Feb 10, 2020 02:00
JCM, Vol. 9, Pages 485: The Pathogenesis of Adenomyosis vis-à-vis Endometriosis Journal of Clinical Medicine doi: 10.3390/jcm9020485 Authors: Guo Adenomyosis is used to be called endometriosis interna, and deep endometriosis is now called adenomyosis externa. Thus, there is a question as to whether adenomyosis is simply endometriosis of the uterus, either from the perspective of pathogenesis or pathophysiology. In this manuscript, a comprehensive review was performed with a literature...
Mon Feb 10, 2020 02:00
JCM, Vol. 9, Pages 483: Photodynamic Therapy in Primary Breast Cancer Journal of Clinical Medicine doi: 10.3390/jcm9020483 Authors: Banerjee El-Sheikh Malhotra Mosse Parker Williams MacRobert Hamoudi Bown Keshtgar Photodynamic therapy (PDT) is a technique for producing localized necrosis with light after prior administration of a photosensitizing agent. This study investigates the nature, safety, and efficacy of PDT for image-guided treatment of primary...
Mon Feb 10, 2020 02:00
JCM, Vol. 9, Pages 484: The Impact of the Circadian Genes CLOCK and ARNTL on Myocardial Infarction Journal of Clinical Medicine doi: 10.3390/jcm9020484 Authors: Škrlec Milić Steiner The circadian rhythm regulates various physiological mechanisms, and its disruption can promote many disorders. Disturbance of endogenous circadian rhythms enhances the chance of myocardial infarction (MI), showing that circadian clock genes could have a crucial function in the onset of the disease....
Mon Feb 10, 2020 02:00
JCM, Vol. 9, Pages 482: Urinary Liver-Type Fatty-Acid-Binding Protein Predicts Long-Term Adverse Outcomes in Medical Cardiac Intensive Care Units Journal of Clinical Medicine doi: 10.3390/jcm9020482 Authors: Naruse Ishii Takahashi Kitagawa Nishimura Kawai Muramatsu Harada Yamada Fujiwara Hayashi Motoyama Sarai Watanabe Izawa Ozaki We prospectively investigated the prognostic value of urinary liver-type fatty-acid-binding protein...
Mon Feb 10, 2020 02:00
JoF, Vol. 6, Pages 23: An Overview on Conventional and Non-Conventional Therapeutic Approaches for the Treatment of Candidiasis and Underlying Resistance Mechanisms in Clinical Strains Journal of Fungi doi: 10.3390/jof6010023 Authors: Salazar Simões Pedro Pinheiro Carvalho Mira Fungal infections and, in particular, those caused by species of the Candida genus, are growing at an alarming rate and have high associated rates of mortality and morbidity. These infections,...
Mon Feb 10, 2020 02:00
Life, Vol. 10, Pages 15: Coupling of Cell Division and Differentiation in Arabidopsis thaliana Cultured Cells with Interaction of Ethylene and ABA Signaling Pathways Life doi: 10.3390/life10020015 Authors: Novikova Stepanchenko Zorina Nosov Rakitin Moshkov Los Recent studies indicate direct links between molecular cell cycle and cell differentiation machineries. Ethylene and abscisic acid (ABA) are known to affect cell division and differentiation, but the mechanisms...
Mon Feb 10, 2020 02:00
Medical Sciences, Vol. 8, Pages 10: Persistent Urogenital Schistosomiasis and Its Associated Morbidity in Endemic Communities within Southern Ghana: Suspected Praziquantel Resistance or Reinfection? Medical Sciences doi: 10.3390/medsci8010010 Authors: Tetteh-Quarcoo Forson Amponsah Ahenkorah Opintan Ocloo Okine Aryee Afutu Anang Ayeh-Kumi Background: schistosomiasis is a neglected tropical disease caused by helminths of the genus Schistosoma....
Mon Feb 10, 2020 02:00
Medicina, Vol. 56, Pages 68: Electrocardiographic Changes in Liver Cirrhosis—Clues for Cirrhotic Cardiomyopathy Medicina doi: 10.3390/medicina56020068 Authors: Toma Stanciu Zgura Bacalbasa Diaconu Iliescu Background and Objectives: Cirrhotic cardiomyopathy is a chronic cardiac dysfunction associated with liver cirrhosis, in patients without previous heart disease, irrespective of the etiology of cirrhosis. Electrocardiography (ECG) is an important way to evaluate...
Mon Feb 10, 2020 02:00
Medicina, Vol. 56, Pages 69: Markers of Subclinical Cardiovascular Disease in Patients with Adrenal Incidentaloma Medicina doi: 10.3390/medicina56020069 Authors: Szychlińska Baranowska-Jurkun Matuszewski Wołos-Kłosowicz Bandurska-Stankiewicz Due to the growing availability of imaging examinations the percentage of patients with incidentally diagnosed adrenal tumors has increased. The vast majority of these lesions are benign, non-functioning adenomas, although according...
Mon Feb 10, 2020 02:00
Metabolites, Vol. 10, Pages 63: Gut Microbiota is the Key to the Antidepressant Effect of Chaihu-Shu-Gan-San Metabolites doi: 10.3390/metabo10020063 Authors: Yu Jia Zhang Shang Zhang Ma Zou Accumulating evidence highlights the link between gut microbiota and depression. As an antidepressant herbal drug in clinic, Chaihu-Shu-Gan-San (CSGS) has also been used in China for the treatment of various gastrointestinal disorders. Therefore, we hypothesize that the gut...
Mon Feb 10, 2020 02:00
Metabolites, Vol. 10, Pages 62: Use of Chemometrics for Correlating Carobs Nutritional Compositional Values with Geographic Origin Metabolites doi: 10.3390/metabo10020062 Authors: Kokkinofta Yiannopoulos Stylianou Agapiou Carobs unique compositional and biological synthesis enables their characterization as functional foods. In the present study, 76 samples derived from fruit and seeds of carobs, with origin from the countries of the Mediterranean region (Cyprus, Greece,...
Mon Feb 10, 2020 02:00
Metabolites, Vol. 10, Pages 61: Association of Circulating COMP and YKL-40 as Markers of Metabolic Changes of Cartilage with Adipocytokines in Juvenile Idiopathic Arthritis Metabolites doi: 10.3390/metabo10020061 Authors: Winsz-Szczotka Kuźnik-Trocha Gruenpeter Wojdas Dąbkowska Olczyk The aim of this study was to evaluate the association of circulating cartilage oligomeric matrix protein (COMP) and human cartilage glycoprotein-39 (YKL-40) as markers of metabolic...
Mon Feb 10, 2020 02:00
MPs, Vol. 3, Pages 15: A Fast and Accurate Method to Identify and Quantify Enzymes in Brush-Border Membranes: In Situ Hydrolysis Followed by Nano LC-MS/MS Methods and Protocols doi: 10.3390/mps3010015 Authors: Brun Magallanes Martínez del Rio Barrett-Wilt Karasov Caviedes-Vidal A simple method for the identification of brush-border membrane α-glucosidases is described. The proteins were first solubilized and separated in a gel under native, non-denaturing,...
Mon Feb 10, 2020 02:00
Microorganisms, Vol. 8, Pages 236: Community Structures and Antifungal Activity of Root-Associated Endophytic Actinobacteria in Healthy and Diseased Cucumber Plants and Streptomyces sp. HAAG3-15 as a Promising Biocontrol Agent Microorganisms doi: 10.3390/microorganisms8020236 Authors: Cao Li Wang Yu Xu Wang Zhao Xiang Microorganisms related to plant roots are vital for plant growth and health and considered to be the second genome of the plant. When the plant...
Mon Feb 10, 2020 02:00
Microorganisms, Vol. 8, Pages 237: Identification and Heterologous Expression of the Albucidin Gene Cluster from the Marine Strain Streptomyces Albus Subsp. Chlorinus NRRL B-24108 Microorganisms doi: 10.3390/microorganisms8020237 Authors: Myronovskyi Rosenkränzer Stierhof Petzke Seiser Luzhetskyy Herbicides with new modes of action and safer toxicological and environmental profiles are needed to manage the evolution of weeds that are resistant to commercial herbicides....
Mon Feb 10, 2020 02:00
Microorganisms, Vol. 8, Pages 235: Interferon-γ Possesses Anti-Microbial and Immunomodulatory Activity on a Chlamydia Trachomatis Infection Model of Primary Human Synovial Fibroblasts Microorganisms doi: 10.3390/microorganisms8020235 Authors: Di Pietro Filardo Frasca Scagnolari Manera Sessa Antonelli Sessa Chlamydia trachomatis, an obligate intracellular pathogen, is the most common cause of bacterial sexually transmitted diseases, and it is potentially...
Mon Feb 10, 2020 02:00
Microorganisms, Vol. 8, Pages 234: Predominance of Distinct Listeria Innocua and Listeria Monocytogenes in Recurrent Contamination Events at Dairy Processing Facilities Microorganisms doi: 10.3390/microorganisms8020234 Authors: Kaszoni-Rückerl Mustedanagic Muri-Klinger Brugger Wagner Wagner Stessl : The genus Listeria now comprises up to now 21 recognized species and six subspecies, with L. monocytogenes and L. innocua as the most prevalent sensu stricto associated...
Mon Feb 10, 2020 02:00
Molecules, Vol. 25, Pages 764: Synthesis and Anticancer Cytotoxicity of Azaaurones Overcoming Multidrug Resistance Molecules doi: 10.3390/molecules25030764 Authors: Tóth Szepesi Tran-Nguyen Sarkadi Német Falson Di Pietro Szakács Boumendjel The resistance of tumors against anticancer drugs is a major impediment for chemotherapy. Tumors often develop multidrug resistance as a result of the cellular efflux of chemotherapeutic agents by ABC transporters such...
Mon Feb 10, 2020 02:00
Molecules, Vol. 25, Pages 763: Discrimination of Cultivated Regions of Soybeans (Glycine max) Based on Multivariate Data Analysis of Volatile Metabolite Profiles Molecules doi: 10.3390/molecules25030763 Authors: Kim Kim Lee Lee Shin Kang Choi Kim Soybean (Glycine max) is a major crop cultivated in various regions and consumed globally. The formation of volatile compounds in soybeans is influenced by the cultivar as well as environmental factors, such as the...
Mon Feb 10, 2020 02:00
Molecules, Vol. 25, Pages 762: Therapeutic Potential of Flavonoids in Pain and Inflammation: Mechanisms of Action, Pre-Clinical and Clinical Data, and Pharmaceutical Development Molecules doi: 10.3390/molecules25030762 Authors: Ferraz Carvalho Manchope Artero Rasquel-Oliveira Fattori Casagrande Verri Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a consequence of the pathological functioning of the nervous system...
Mon Feb 10, 2020 02:00
Molecules, Vol. 25, Pages 761: Direct Recovery of the Rare Earth Elements Using a Silk Displaying a Metal-Recognizing Peptide Molecules doi: 10.3390/molecules25030761 Authors: Ishida Hatanaka Hosokawa Kojima Iizuka Teramoto Sezutsu Kameda Rare earth elements (RE) are indispensable metallic resources in the production of advanced materials; hence, a cost- and energy-effective recovery process is required to meet the rapidly increasing RE demand. Here, we propose...
Mon Feb 10, 2020 02:00
Molecules, Vol. 25, Pages 760: Anticancer Activities of the Quinone-Methide Triterpenes Maytenin and 22-β-hydroxymaytenin Obtained from Cultivated Maytenus ilicifolia Roots Associated with Down-Regulation of miRNA-27a and miR-20a/miR-17-5p Molecules doi: 10.3390/molecules25030760 Authors: Camila Hernandes Lucyene Miguita Romario Oliveira de Sales Elisangela de Paula Silva Pedro Omori Ribeiro de Mendonça Bruna Lorencini da Silva Maria de Fatima Guarizo Klingbeil Monica...
Mon Feb 10, 2020 02:00
Molecules, Vol. 25, Pages 758: Bone Mineral Affinity of Polyphosphodiesters Molecules doi: 10.3390/molecules25030758 Authors: Yasuhiko Iwasaki Biomimetic molecular design is a promising approach for generating functional biomaterials such as cell membrane mimetic blood-compatible surfaces, mussel-inspired bioadhesives, and calcium phosphate cements for bone regeneration. Polyphosphoesters (PPEs) are candidate biomimetic polymer biomaterials that are of interest due to their biocompatibility,...
Mon Feb 10, 2020 02:00
Molecules, Vol. 25, Pages 757: Quercetin Inhibits Cell Survival and Metastatic Ability via the EMT-mediated Pathway in Oral Squamous Cell Carcinoma Molecules doi: 10.3390/molecules25030757 Authors: Kim Lee Kim Kim Park This study aimed to investigate whether quercetin exerts anticancer effects on oral squamous cell carcinoma (OSCC) cell lines and to elucidate its mechanism of action. These anticancer effects in OSCC cells were assessed using an MTT assay, flow cytometry...
Mon Feb 10, 2020 02:00
Molecules, Vol. 25, Pages 759: Stabilizing the Oil-in-Water Emulsions Using the Mixtures of Dendrobium Officinale Polysaccharides and Gum Arabic or Propylene Glycol Alginate Molecules doi: 10.3390/molecules25030759 Authors: Bo Wang Haiyan Tian Dong Xiang Coconut oil-in-water emulsions were prepared using three polysaccharides: Dendrobium officinale polysaccharide (DOP), propylene glycol alginate (PGA), gum arabic (GA) and their polysaccharide complexes as emulsifiers. The effects...
Mon Feb 10, 2020 02:00
Nanomaterials, Vol. 10, Pages 303: Facile Preparation of Stable Solid-State Carbon Quantum Dots with Multi-Peak Emission Nanomaterials doi: 10.3390/nano10020303 Authors: Zheng Zheng Wang Yang Lu Liu Aggregation-caused quenching (ACQ) effect, known as the main cause to restrain solid-state luminescence of carbon quantum dots (CQDs), hinders further application of CQDs in white light-emitting diodes (WLED). Here, a complex of CQDs and phthalimide crystals (CQDs/PC)...
Mon Feb 10, 2020 02:00
Nanomaterials, Vol. 10, Pages 296: Sol-Gel Processed TiO2 Nanotube Photoelectrodes for Dye-Sensitized Solar Cells with Enhanced Photovoltaic Performance Nanomaterials doi: 10.3390/nano10020296 Authors: Tsvetkov Larina Ku Kang Shevaleevskiy The performance of dye-sensitized solar cells (DSCs) critically depends on the efficiency of electron transport within the TiO2-dye-electrolyte interface. To improve the efficiency of the electron transfer the conventional structure of...
Mon Feb 10, 2020 02:00
Nanomaterials, Vol. 10, Pages 298: Multifunctional, CD44v6-Targeted ORMOSIL Nanoparticles Enhance Drugs Toxicity in Cancer Cells Nanomaterials doi: 10.3390/nano10020298 Authors: Morillas-Becerril Peta Gabrielli Russo Lubian Nodari Ferlin Scrimin Palù Barzon Castagliuolo Mancin Trevisan Drug-loaded, PEGylated, organic-modified silica (ORMOSIL) nanoparticles prepared by microemulsion condensation of vinyltriethoxysilane (VTES) were investigated...
Mon Feb 10, 2020 02:00
Nanomaterials, Vol. 10, Pages 301: Evaluation of Acetaminophen Release from Biodegradable Poly (Vinyl Alcohol) (PVA) and Nanocellulose Films Using a Multiphase Release Mechanism Nanomaterials doi: 10.3390/nano10020301 Authors: O’Donnell Oporto-Velásquez Comolli Biodegradable polymers hold great therapeutic value, especially through the addition of additives for controlled drug release. Nanocellulose has shown promise in drug delivery, yet usually requires chemical crosslinking...
Mon Feb 10, 2020 02:00
Nanomaterials, Vol. 10, Pages 300: Fabrication and Deposition of Copper and Copper Oxide Nanoparticles by Laser Ablation in Open Air Nanomaterials doi: 10.3390/nano10020300 Authors: Fernández-Arias Boutinguiza del Val Riveiro Rodríguez Arias-González Gil Pou The proximity of the “post-antibiotic era”, where infections and minor injuries could be a cause of death, there are urges to seek an alternative for the cure of infectious diseases....
Mon Feb 10, 2020 02:00
Nanomaterials, Vol. 10, Pages 297: Current Transport Mechanism in Palladium Schottky Contact on Si-Based Freestanding GaN Nanomaterials doi: 10.3390/nano10020297 Authors: Lee Ahn Vu Lee Jeong Hahm Kim Park In this study, the charge transport mechanism of Pd/Si-based FS-GaN Schottky diodes was investigated. A temperature-dependent current–voltage analysis revealed that the I-V characteristics of the diodes show a good rectifying behavior with a large...
Mon Feb 10, 2020 02:00
Nanomaterials, Vol. 10, Pages 299: Performance of Intrinsic and Modified Graphene for the Adsorption of H2S and CH4: A DFT Study Nanomaterials doi: 10.3390/nano10020299 Authors: Gao Zhou Wang Xu Zeng In this study, the adsorption performances of graphene before and after modification to H2S and CH4 molecules were studied using first principles with the density functional theory (DFT) method. The most stable adsorption configuration, the adsorption energy, the density...
Mon Feb 10, 2020 02:00
Nanomaterials, Vol. 10, Pages 302: Cu2Se Nanoparticles Encapsulated by Nitrogen-Doped Carbon Nanofibers for Efficient Sodium Storage Nanomaterials doi: 10.3390/nano10020302 Authors: Hu Shang Akinoglu Wang Zhou Cu2Se with high theoretical capacity and good electronic conductivity have attracted particular attention as anode materials for sodium ion batteries (SIBs). However, during electrochemical reactions, the large volume change of Cu2Se results in poor rate performance...
Mon Feb 10, 2020 02:00
Nanomaterials, Vol. 10, Pages 295: The Nanosized Dye Adsorbents for Water Treatment Nanomaterials doi: 10.3390/nano10020295 Authors: Homaeigohar Clean water is a vital element for survival of any living creature and, thus, crucially important to achieve largely and economically for any nation worldwide. However, the astonishingly fast trend of industrialization and population growth and the arisen extensive water pollutions have challenged access to clean water across the world. In...
Mon Feb 10, 2020 02:00
Nanomaterials, Vol. 10, Pages 294: Star-Shaped Fe3-xO4-Au Core-Shell Nanoparticles: From Synthesis to SERS Application Nanomaterials doi: 10.3390/nano10020294 Authors: Nguyen Lau-Truong Mammeri Ammar In this work, the preparation of magneto-plasmonic granular nanostructures and their evaluation as efficient substrates for magnetically assisted surface enhanced Raman spectroscopy (SERS) sensing are discussed. These nanostructures consist of star-shaped gold Au shell grown...
Mon Feb 10, 2020 02:00
Nutrients, Vol. 12, Pages 440: The Effects of Community Home Visit and Peer Group Nutrition Intervention Delivery Platforms on Nutrition Outcomes in Low and Middle-Income Countries: A Systematic Review and Meta-Analysis Nutrients doi: 10.3390/nu12020440 Authors: Amynah Janmohamed Nazia Sohani Zohra S Lassi Zulfiqar A Bhutta Weak delivery systems reduce the potential of evidence-supp orted interventions to improve nutrition. We synthesized the evidence for the effectiveness of...
Mon Feb 10, 2020 02:00
Nutrients, Vol. 12, Pages 444: Nutritional Status as a Mediator of Fatigue and Its Underlying Mechanisms in Older People Nutrients doi: 10.3390/nu12020444 Authors: Domenico Azzolino Beatrice Arosio Emanuele Marzetti Riccardo Calvani Matteo Cesari Fatigue is an often-neglected symptom but frequently complained of by older people, leading to the inability to continue functioning at a normal level of activity. Fatigue is frequently associated with disease conditions and impacts...
Mon Feb 10, 2020 02:00
Nutrients, Vol. 12, Pages 442: Affective and Enjoyment Responses to Short-Term High-Intensity Interval Training with Low-Carbohydrate Diet in Overweight Young Women Nutrients doi: 10.3390/nu12020442 Authors: Kong Hu Liu Shi Zou Sun Zhang Nie Low-carbohydrate diets (LCs) seem effective on weight reduction and maintenance. However, the affect and enjoyment of exercise during LCs is not clear. The purpose of the present study was to compare the psychological...
Mon Feb 10, 2020 02:00
Nutrients, Vol. 12, Pages 441: Dietary Advanced Glycation Endproducts Decrease Glucocorticoid Sensitivity In Vitro Nutrients doi: 10.3390/nu12020441 Authors: van der Lugt Weseler Vrolijk Opperhuizen Bast Glucocorticoids are very effective anti-inflammatory drugs and widely used for inflammatory bowel disease (IBD) patients. However, approximately 20% of IBD patients do not respond to glucocorticoids and the reason for this is largely unknown. Dietary advanced glycation...
Mon Feb 10, 2020 02:00
Nutrients, Vol. 12, Pages 443: Independent and Joint Associations of Physical Activity and Dietary Behavior with Older Adults’ Lower Limb Strength Nutrients doi: 10.3390/nu12020443 Authors: Lai Lin Chou Huang Hsueh Park Liao Studies have indicated that sufficient physical activity levels and balanced dietary behavior are independently related to physical function in older populations; however, their joint association with physical function remain unclear. This...
Mon Feb 10, 2020 02:00
Nutrients, Vol. 12, Pages 439: Antimicrobial Locks in Patients Receiving Home Parenteral Nutrition Nutrients doi: 10.3390/nu12020439 Authors: Daoud Wanten Joly Catheter-related bloodstream infection (CRBSI) is one of the most common and potentially fatal complications in patients receiving home parenteral nutrition (HPN). In order to prevent permanent venous access loss, catheter locking with an antimicrobial solution has received significant interest and is often a favored...
Mon Feb 10, 2020 02:00
Particles, Vol. 3, Pages 87-98: New Canonical and Grand Canonical Density of States Techniques for Finite Density Lattice QCD Particles doi: 10.3390/particles3010008 Authors: Christof Gattringer Michael Mandl Pascal Törek We discuss two new density of states approaches for finite density lattice QCD (Quantum Chromo Dynamics). The paper extends a recent presentation of the new techniques based on Wilson fermions, while here, we now discuss and test the case of finite density QCD...
Mon Feb 10, 2020 02:00
Pathogens, Vol. 9, Pages 108: Transient Transfection of the Zoonotic Parasite Babesia microti Pathogens doi: 10.3390/pathogens9020108 Authors: Liu Ji Rizk Adjou Moumouni Galon Li Li Zheng Benedicto Tumwebaze Asada Xuan The development of genetic manipulation techniques has been reported in many protozoan parasites over the past few years. However, these techniques have not been established for Babesia microti. Here, we report the first successful...
Mon Feb 10, 2020 02:00
Pharmaceutics, Vol. 12, Pages 144: Evaluation of the Solid Dispersion System Engineered from Mesoporous Silica and Polymers for the Poorly Water Soluble Drug Indomethacin: In Vitro and In Vivo Pharmaceutics doi: 10.3390/pharmaceutics12020144 Authors: Xi Zhang Fei Cui Xie Chen Xu This work explored absorption efficacy via an in vivo imaging system and parallel artificial membrane penetration in indomethacin (IMC) solid dispersion (SD) systems. Two different polymer...
Mon Feb 10, 2020 02:00
Plants, Vol. 9, Pages 227: Proteomics Revealed Distinct Responses to Salinity between the Halophytes Suaeda maritima (L.) Dumort and Salicornia brachiata (Roxb) Plants doi: 10.3390/plants9020227 Authors: Benjamin Miras-Moreno Araniti Salehi Bernardo Parida Lucini Plant resistance to salinity stress is one of the main challenges of agriculture. The comprehension of the molecular and cellular mechanisms involved in plant tolerance to salinity can help to contrast...
Mon Feb 10, 2020 02:00
Plants, Vol. 9, Pages 226: The Interaction between Leaf Allelopathy and Symbiosis with Rhizobium of Ulex europaeus on Hawaii Island Plants doi: 10.3390/plants9020226 Authors: Hozawa Nawata : The objective of this study was to assess the magnitudes of the leaf allelopathy of Ulex europaeus in two different habitats, and discuss the driver of the differences, including rhizobia. The magnitudes of leaf allelopathy of the samples collected in two different habitats were assessed by...
Mon Feb 10, 2020 02:00
Plants, Vol. 9, Pages 225: ACTIN7 Is Required for Perinuclear Clustering of Chloroplasts during Arabidopsis Protoplast Culture Plants doi: 10.3390/plants9020225 Authors: Sheahan Collings Rose McCurdy In Arabidopsis, the actin gene family comprises eight expressed and two non-expressed ACTIN (ACT) genes. Of the eight expressed isoforms, ACT2, ACT7, and ACT8 are differentially expressed in vegetative tissues and may perform specific roles in development. Using tobacco mesophyll...
Mon Feb 10, 2020 02:00
Religions, Vol. 11, Pages 80: A Perspectival Account of Acedia in the Writings of Kierkegaard Religions doi: 10.3390/rel11020080 Authors: Brandt Dahm McAllister Søren Kierkegaard is well-known as an original philosophical thinker, but less known is his reliance upon and development of the Christian tradition of the Seven Deadly Sins, in particular the vice of acedia, or sloth. As acedia has enjoyed renewed interest in the past century or so, commentators have attempted...
Mon Feb 10, 2020 02:00
Religions, Vol. 11, Pages 79: ‘Non-Religion’ as Part of the ‘Religion’ Category in International Human Rights Religions doi: 10.3390/rel11020079 Authors: Nixon ‘Religion’ still occupies and maintains a position of formal and informal privilege in many current societies. It retains these privileges despite the increasing numbers of people who label themselves ‘non-religious’. There is also evidence that overtly non-religious people are being persecuted...
Mon Feb 10, 2020 02:00
Religions, Vol. 11, Pages 81: Contradictions, Contextuality, and Conceptuality: Why Is It That Luther Is Not a Feminist? Religions doi: 10.3390/rel11020081 Authors: Wiberg Pedersen It is the aim of this article to constructively discuss some of the feminist critique that has been raised against the sixteenth century reformer, Martin Luther, and concomitantly to demonstrate the complexity, and primarily liberal aspects, of his view of women. At its outset, the article points to the fact...
Mon Feb 10, 2020 02:00
Technologies, Vol. 8, Pages 15: High Throughput Implementation of the Keccak Hash Function Using the Nios-II Processor Technologies doi: 10.3390/technologies8010015 Authors: Argyrios Sideris Theodora Sanida Minas Dasygenis Presently, cryptographic hash functions play a critical role in many applications, such as digital signature systems, security communications, protocols, and network security infrastructures. The new standard cryptographic hash function is Secure Hash Algorithm...
Mon Feb 10, 2020 02:00
Toxics, Vol. 8, Pages 10: Enchytraeus crypticus Avoid Soil Spiked with Microplastic Toxics doi: 10.3390/toxics8010010 Authors: Stephan Pflugmacher Johanna H. Huttunen Marya-Anne von Wolff Olli-Pekka Penttinen Yong Jun Kim Sanghun Kim Simon M. Mitrovic Maranda Esterhuizen-Londt Microplastics (MPs) of varying sizes are widespread pollutants in our environment. The general opinion is that the smaller the size, the more dangerous the MPs are due to enhanced uptake possibilities....
Mon Feb 10, 2020 02:00
Toxins, Vol. 12, Pages 111: Polymethoxy-1-Alkenes Screening of Chlorella and Spirulina Food Supplements Coupled with In Vivo Toxicity Studies Toxins doi: 10.3390/toxins12020111 Authors: Henao Murphy Falfushynska Horyn Evans Klimaszyk Rzymski Selected species of cyanobacteria and green algae have been reported to produce lipophilic polymethoxy-1-alkenes (PMAs) which were shown to exhibit in vivo teratogenicity. Considering that information on PMAs in Arthospira...
Mon Feb 10, 2020 02:00
Toxins, Vol. 12, Pages 110: Can Botulinum Toxin A Play A Role In Treatment Of Chronic Pelvic Pain Syndrome In Female Patients?—Clinical and Animal Evidence Toxins doi: 10.3390/toxins12020110 Authors: Chen Meng Chronic pelvic pain (CPP) is defined as chronic pain and inflammation in the pelvic organs for more than six months. There are wide ranges of clinical presentations, including pelvic pain, painful intercourse, irritable bowel syndrome, and pain during urinating. Chronic pelvic...
Mon Feb 10, 2020 02:00
Vaccines, Vol. 8, Pages 80: Emergency Foot-and-Mouth Disease Vaccines A Malaysia 97 and A22 Iraq 64 Offer Good Protection against Heterologous Challenge with A Variant Serotype A ASIA/G-IX/SEA-97 Lineage Virus Vaccines doi: 10.3390/vaccines8010080 Authors: B. Dekker Eblé van Hemert-Kluitenberg Weerdmeester Horsington Vosloo W The continuous emergence of foot-and-mouth disease virus (FMDV) serotype A variants in South East Asia is of concern for international...
Mon Feb 10, 2020 02:00
Vaccines, Vol. 8, Pages 79: Evaluation of the Potency of Two Pyolysin-Derived Recombinant Proteins as Vaccine Candidates of Trueperella Pyogenes in a Mouse Model: Pyolysin Oligomerization and Structural Change Affect the Efficacy of Pyolysin-Based Vaccines Vaccines doi: 10.3390/vaccines8010079 Authors: Yang Liang Wang Ma Wang Zhang Trueperella pyogenes (T. pyogenes) is an important opportunistic pathogen in livestock and wild animals. However, only one commercial...
Mon Feb 10, 2020 02:00
Veterinary Sciences, Vol. 7, Pages 21: Rapid Resolution of Large Bowel Diarrhea after the Administration of a Combination of a High-Fiber Diet and a Probiotic Mixture in 30 Dogs Veterinary Sciences doi: 10.3390/vetsci7010021 Authors: Rossi Cerquetella Gavazza Galosi Berardi Mangiaterra Mari Suchodolski Lidbury Steiner Pengo Canine fiber responsive diarrhea is a form of chronic colitis that improves clinically after adding fiber to the diet. In...
Mon Feb 10, 2020 02:00
Viruses, Vol. 12, Pages 194: Potential Maternal and Infant Outcomes from (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections Viruses doi: 10.3390/v12020194 Authors: Schwartz Graham In early December 2019 a cluster of cases of pneumonia of unknown cause was identified in Wuhan, a city of 11 million persons in the People’s Republic of China. Further investigation revealed these cases to result from infection...
Mon Feb 10, 2020 02:00
Viruses, Vol. 12, Pages 196: Changes in the Transmission Dynamic of Chikungunya Virus in Southeastern Senegal Viruses doi: 10.3390/v12020196 Authors: Sow Nikolay Faye Cauchemez Cano Diallo Faye Sadio Ndiaye Weaver Dia Sall Malvy In Senegal, chikungunya virus (CHIKV) is maintained in a sylvatic cycle and causes sporadic cases or small outbreaks in rural areas. However, little is known about the influence of the environment on its transmission....
Mon Feb 10, 2020 02:00
Viruses, Vol. 12, Pages 195: A Conserved Carboxylesterase Inhibits Tobacco mosaic virus (TMV) Accumulation in Nicotiana benthamiana Plants Viruses doi: 10.3390/v12020195 Authors: Guo Wong A carboxylesterase (CXE) or carboxylic-ester hydrolase is an enzyme that catalyzes carboxylic ester and water into alcohol and carboxylate. In plants, CXEs have been implicated in defense, development, and secondary metabolism. We discovered a new CXE gene in Nicotiana benthamiana that is related...
Mon Feb 10, 2020 02:00
Viruses, Vol. 12, Pages 193: Comparison of CRISPR and Marker-Based Methods for the Engineering of Phage T7 Viruses doi: 10.3390/v12020193 Authors: Grigonyte Harrison MacDonald Montero-Blay Tridgett Duncan Sagona Constantinidou Jaramillo Millard With the recent rise in interest in using lytic bacteriophages as therapeutic agents, there is an urgent requirement to understand their fundamental biology to enable the engineering of their genomes. Current...
Mon Feb 10, 2020 02:00
Water, Vol. 12, Pages 475: Head Losses of Horizontal Bar Racks as Fish Guidance Structures Water doi: 10.3390/w12020475 Authors: Julian Meister Helge Fuchs Claudia Beck Ismail Albayrak Robert M. Boes Horizontal bar racks have been used as trash racks at hydropower plants since the 1920s. With the installation of the first horizontal bar rack bypass system at a hydropower plant as a downstream fish passage facility in 2006, these racks rapidly gained importance as fish protection...
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Water, Vol. 12, Pages 473: Unraveling Aquatic Quality Controls of a Nearly Undisturbed Mediterranean Island (Samothraki, Greece) Water doi: 10.3390/w12020473 Authors: Skoulikidis Lampou Laschou Due to its rough, mountainous relief, Samothraki remains one of the last minimally disturbed islands in the Mediterranean. This paper examines the hydrogeochemical regime of the island’s surface waters as it results from geological, morphological, and hydro(geo)logical controls...
Mon Feb 10, 2020 02:00
Water, Vol. 12, Pages 474: An Overview of Managed Aquifer Recharge in Mexico and Its Legal Framework
Water, Vol. 12, Pages 474: An Overview of Managed Aquifer Recharge in Mexico and Its Legal Framework Water doi: 10.3390/w12020474 Authors: Cruz-Ayala Megdal In Mexico, one hundred of the 188 most important aquifers dedicated to agriculture and human consumption are over-exploited and 32 are affected by seawater intrusion in coastal areas. Considering that Mexico relies on groundwater, it is vital to develop a portfolio of alternatives to recover aquifers and examine policies and...
Mon Feb 10, 2020 02:00
Water, Vol. 12, Pages 471: Mapping of Groundwater Potential Zones in Crystalline Terrain Using Remote Sensing, GIS Techniques, and Multicriteria Data Analysis (Case of the Ighrem Region, Western Anti-Atlas, Morocco) Water doi: 10.3390/w12020471 Authors: Benjmel Amraoui Boutaleb Ouchchen Tahiri Touab This research work is intended as a contribution to the development of a multicriteria methodology, combining several factors to control the availability of groundwater...
Mon Feb 10, 2020 02:00
Water, Vol. 12, Pages 470: Drought Trends in Balochistan Water doi: 10.3390/w12020470 Authors: Naz Dars Ansari Jamro Krakauer Drought is a severe threat, especially in the arid regions of Pakistan, such as the Balochistan Province. The aim of this study is to analyze drought trends in Balochistan using Standard Precipitation Index (SPI) at the 3-month accumulation timescale. The monthly rainfall data of 10 stations were collected from the Pakistan Meteorological Department...
Mon Feb 10, 2020 02:00
Water, Vol. 12, Pages 472: Modellingof Future Extreme Storm Surges at the NW Mediterranean Coast (Spain) Water doi: 10.3390/w12020472 Authors: Jue Lin-Ye Manuel García-León Vicente Gràcia María Isabel Ortego Piero Lionello Dario Conte Begoña Pérez-Gómez Agustín Sánchez-Arcilla Storm surges are one of the main drivers for extreme flooding at the coastal areas. Such events can be characterized with the maximum level in an extreme storm surge event (surge peak), as...
Mon Feb 10, 2020 02:00
Water, Vol. 12, Pages 468: Improved Planning of Energy Recovery in Water Systems Using a New Analytic Approach to PAT Performance Curves Water doi: 10.3390/w12020468 Authors: Pérez-Sánchez Sánchez-Romero Ramos López-Jiménez The use of pumps working as turbines (PATs) to improve the energy efficiency of water networks has been studied in the last years. This recovery system is justified due to a low investment contrasting with the capacity to take advantage in certain points...
Mon Feb 10, 2020 02:00
Water, Vol. 12, Pages 469: Field Investigation on Hydroabrasion in High-Speed Sediment-Laden Flows at Sediment Bypass Tunnels Water doi: 10.3390/w12020469 Authors: Müller-Hagmann Albayrak Auel Boes Wear due to sediment particles in fluid flows, also termed ‘hydroabrasion’ or simply ‘abrasion’, is an omnipresent issue at hydraulic structures as well as in bedrock rivers. However, interactions between flow field, particle motion, channel...
Mon Feb 10, 2020 02:00
Water, Vol. 12, Pages 466: Microbial Assisted Hexavalent Chromium Removal in Bioelectrochemical Systems Water doi: 10.3390/w12020466 Authors: Beretta Daghio Espinoza Tofalos Franzetti Mastorgio Saponaro Sezenna Groundwater is the environmental matrix that is most frequently affected by anthropogenic hexavalent chromium contamination. Due to its carcinogenicity, Cr(VI) has to be removed, using environmental-friendly and economically sustainable remediation technologies....
Mon Feb 10, 2020 02:00
Water, Vol. 12, Pages 465: The Action Mechanism of Rotor–Stator Interaction on Hydraulic and Hydroacoustic Characteristics of a Jet Centrifugal Pump Impeller and Performance Improvement Water doi: 10.3390/w12020465 Authors: Guo Li Zhang Han The aim of this study was to investigate the action mechanism of the rotor–stator interaction (RSI) on the transient flow field and hydrodynamic noise field inside the impeller of jet centrifugal pumps (JCPs) and optimize effects...
Mon Feb 10, 2020 02:00
Water, Vol. 12, Pages 467: Possible Hydrochemical Processes Influencing Dissolved Solids in Surface Water and Groundwater of the Kaidu River Basin, Northwest China Water doi: 10.3390/w12020467 Authors: Li Chen Jia Lv Hydrochemical processes under intense human activities were explored on the basis of the hydrochemical characteristics of 109 surface water samples and 129 groundwater samples collected during August 2015 to September 2016, in the Kaidu River Basin. Results...
Mon Feb 10, 2020 02:00
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