Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study.

Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study.:

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Modified protocol of omalizumab treatment to prevent carboplatin-induced drug hypersensitivity reactions: a case study.

Clin Transl Allergy. 2020;10:5

Authors: Oude Elberink HNG, Jalving M, Dijkstra H, van de Ven AAJM

Abstract

Carboplatin administration can usually be safely continued via a so-called desensitisation protocol when hypersensitivity reactions arise. Severe break-through reactions that occur early during desensitisation are likely to be IgE-mediated; in that case, addition of omalizumab premedication should be strongly considered.

PMID: 32015827 [PubMed]