Τρίτη 30 Μαρτίου 2021

Sentinel lymph node biopsy versus elective neck dissection: long-term oncologic outcomes in clinically node-negative tongue cancer

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Clin Exp Otorhinolaryngol. 2021 Mar 30. doi: 10.21053/ceo.2020.02411. Online ahead of print.

ABSTRACT

OBJECTIVES.: To compare the long-term oncologic outcomes of sentinel lymph node biopsy (SLNB) versus elective neck dissection (END) in clinically node-negative (cN0) tongue cancer.

METHODS.: This is a retrospective cohort study of patients with cN0 tongue cancer from a single institution, including 91 patients in the SLNB group and 120 patients in the END group.

RESULTS.: Overall recurrence rate was no significant difference in the recurrence rate between the two groups. The regional control rate was also comparable between the two groups (p = 0.49). The 5-year RFS was slightly better in the SLNB group (p = 0.427). The 5-year OS was 89.9% in the SLNB group vs. 91.9% in the END group (p = 0.737). In propensity-matched subgroup analysis, the type of neck management did not affect RFS nor OS.

CONCLUSION.: . SLNB showed n on-inferior oncologic outcomes compared to END in patients with cN0 tongue squamous cell carcinoma.

PMID:33781056 | DOI:10.21053/ceo.2020.02411

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