IJMS, Vol. 21, Pages 7828: Evaluation of QSAR Equations for Virtual Screening International Journal of Molecular Sciences doi: 10.3390/ijms21217828 Authors: Jacob Spiegel Hanoch Senderowitz Quantitative Structure Activity Relationship (QSAR) models can inform on the correlation between activities and structure-based molecular descriptors. This information is important for the understanding of the factors that govern molecular properties and for designing new compounds with favorable...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7831: Capacity of Retinal Ganglion Cells Derived from Human Induced Pluripotent Stem Cells to Suppress T-Cells International Journal of Molecular Sciences doi: 10.3390/ijms21217831 Authors: Ayaka Edo Sunao Sugita Yoko Futatsugi Junki Sho Akishi Onishi Yoshiaki Kiuchi Masayo Takahashi Retinal ganglion cells (RGCs) are impaired in patients such as those with glaucoma and optic neuritis, resulting in permanent vision loss. To restore visual function,...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7825: Control of the Photo-Isomerization Mechanism in 3H-Naphthopyrans to Prevent Formation of Unwanted Long-Lived Photoproducts International Journal of Molecular Sciences doi: 10.3390/ijms21217825 Authors: Sabina Brazevic Stanisław Nizinski Michel Sliwa Jiro Abe Michał F. Rode Gotard Burdzinski In the photochromic reactions of 3H-naphthopyrans, two colored isomers TC (transoid-cis) and TT (transoid-trans) are formed. In terms of optimized photo-switchable...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7826: In Cellulo Evaluation of the Therapeutic Potential of NHC Platinum Compounds in Metastatic Cutaneous Melanoma International Journal of Molecular Sciences doi: 10.3390/ijms21217826 Authors: Elsa Charignon Mathilde Bouché Caroline Clave-Darcissac Georges Dahm Gabriel Ichim Anthony Clotagatide Hichem C. Mertani Philippe Telouk Julie Caramel Jean-Jacques Diaz Stéphane Bellemin-Laponnaz Philippe Bouvet Claire Billotey We describe...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7824: Leptin Downregulates Angulin-1 in Active Crohn’s Disease via STAT3 International Journal of Molecular Sciences doi: 10.3390/ijms21217824 Authors: Jia-Chen E. Hu Christian Bojarski Federica Branchi Michael Fromm Susanne M. Krug Crohn’s disease (CD) has an altered intestinal barrier function, yet the underlying mechanisms remain to be disclosed. The tricellular tight junction protein tricellulin is involved in the maintenance of the paracellular...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7823: Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3β Inhibitors with Improved Metabolic Stability International Journal of Molecular Sciences doi: 10.3390/ijms21217823 Authors: Stanislav Andreev Tatu Pantsar Ahmed El-Gokha Francesco Ansideri Mark Kudolo Débora Bublitz Anton Giulia Sita Jenny Romasco Christian Geibel Michael Lämmerhofer Márcia Ines Goettert Andrea Tarozzi Stefan A. Laufer Pierre...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7816: Correction: Haddad, J.G., et al. Doratoxylon apetalum, an Indigenous Medicinal Plant from Mascarene Islands, Is a Potent Inhibitor of Zika and Dengue Virus Infection in Human Cells Int. J. Mol. Sci. 2019, 20, 2382 International Journal of Molecular Sciences doi: 10.3390/ijms21217816 Authors: Juliano G. Haddad Andrea Cristine Koishi Arnaud Gaudry Claudia Nunes Duarte dos Santos Wildriss Viranaicken Philippe Desprès Chaker El Kalamouni The author...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7822: Vitamin D Binding Protein (VDBP) and Its Gene Polymorphisms—The Risk of Malignant Tumors and Other Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21217822 Authors: Dominika Rozmus Alicja Ciesielska Janusz Płomiński Roman Grzybowski Ewa Fiedorowicz Natalia Kordulewska Huub Savelkoul Elżbieta Kostyra Anna Cieślińska Vitamin D is an important component of the endocrine system that controls calcium homeostasis and...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7827: Identification of NPB, NPW and Their Receptor in the Rat Heart International Journal of Molecular Sciences doi: 10.3390/ijms21217827 Authors: Shashank Pandey Zdenek Tuma Elisa Peroni Olivier Monasson Anna Maria Papini Magdalena Chottova Dvorakova Members of neuropeptide B/W signaling system have been predominantly detected and mapped within the CNS. In the rat, this system includes neuropeptide B (NPB), neuropeptide W (NPW) and their specific...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7821: High-Resolution Mass Spectrometry for In Vivo Proteome Dynamics using Heavy Water Metabolic Labeling International Journal of Molecular Sciences doi: 10.3390/ijms21217821 Authors: Rovshan G. Sadygov Cellular proteins are continuously degraded and synthesized. The turnover of proteins is essential to many cellular functions. Combined with metabolic labeling using stable isotopes, LC–MS estimates proteome dynamics in high-throughput and on a large scale....
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7820: The Neutrophil: The Underdog That Packs a Punch in the Fight against Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21217820 Authors: Natasha Ustyanovska Avtenyuk Nienke Visser Edwin Bremer Valerie R. Wiersma The advent of immunotherapy has had a major impact on the outcome and overall survival in many types of cancer. Current immunotherapeutic strategies typically aim to (re)activate anticancer T cell immunity, although the targeting...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7818: Impact of Acute and Chronic Stress on Thrombosis in Healthy Individuals and Cardiovascular Disease Patients International Journal of Molecular Sciences doi: 10.3390/ijms21217818 Authors: Leonardo Sandrini Alessandro Ieraci Patrizia Amadio Marta Zarà Silvia Stella Barbieri Psychological stress induces different alterations in the organism in order to maintain homeostasis, including changes in hematopoiesis and hemostasis. In particular, stress-induced...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7819: Sanfilippo Syndrome: Molecular Basis, Disease Models and Therapeutic Approaches International Journal of Molecular Sciences doi: 10.3390/ijms21217819 Authors: Noelia Benetó Lluïsa Vilageliu Daniel Grinberg Isaac Canals Sanfilippo syndrome or mucopolysaccharidosis III is a lysosomal storage disorder caused by mutations in genes responsible for the degradation of heparan sulfate, a glycosaminoglycan located in the extracellular membrane. Undegraded heparan...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7815: Linagliptin Ameliorates Hepatic Steatosis via Non-Canonical Mechanisms in Mice Treated with a Dual Inhibitor of Insulin Receptor and IGF-1 Receptor International Journal of Molecular Sciences doi: 10.3390/ijms21217815 Authors: Tomoko Okuyama Jun Shirakawa Kazuki Tajima Yoko Ino Heidrun Vethe Yu Togashi Mayu Kyohara Ryota Inoue Daisuke Miyashita Jinghe Li Nozomi Goto Taiga Ichikawa Shingo Yamasaki Haruka Ohnuma Rie Takayanagi...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7817: Truncating Variants Contribute to Hearing Loss and Severe Retinopathy in USH2A-Associated Retinitis Pigmentosa in Japanese Patients International Journal of Molecular Sciences doi: 10.3390/ijms21217817 Authors: Akira Inaba Akiko Maeda Akiko Yoshida Kanako Kawai Yasuhiko Hirami Yasuo Kurimoto Shinji Kosugi Masayo Takahashi USH2A is a common causal gene of retinitis pigmentosa (RP), a progressive blinding disease due to retinal degeneration....
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7813: In the Model Host Caenorhabditis elegans, Sphingosine-1-Phosphate-Mediated Signaling Increases Immunity toward Human Opportunistic Bacteria International Journal of Molecular Sciences doi: 10.3390/ijms21217813 Authors: Lee Escobar Jang Kim Ausubel Mylonakis Sphingosine-1-phophate (S1P) is a sphingolipid-derived signaling molecule that controls diverse cellular functions including cell growth, homeostasis, and stress responses. In a variety...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7814: Investigation of the Impact from IL-2, IL-7, and IL-15 on the Growth and Signaling of Activated CD4+ T Cells International Journal of Molecular Sciences doi: 10.3390/ijms21217814 Authors: Canaan Coppola Brooks Hopkins Steven Huhn Zhimei Du Zuyi Huang William J. Kelly While CAR-T therapy is a growing and promising area of cancer research, it is limited by high cost and the difficulty of consistently culturing T-cells to therapeutically relevant...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7812: Circular RNAs and Their Linear Transcripts as Diagnostic and Prognostic Tissue Biomarkers in Prostate Cancer after Prostatectomy in Combination with Clinicopathological Factors International Journal of Molecular Sciences doi: 10.3390/ijms21217812 Authors: Hannah Rochow Monika Jung Sabine Weickmann Bernhard Ralla Carsten Stephan Sefer Elezkurtaj Ergin Kilic Zhongwei Zhao Klaus Jung Annika Fendler Antonia Franz As new biomarkers,...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7811: Associations of Arginine with Gestational Diabetes Mellitus in a Follow-Up Study International Journal of Molecular Sciences doi: 10.3390/ijms21217811 Authors: Izabela Burzynska-Pedziwiatr Adrian Jankowski Konrad Kowalski Przemyslaw Sendys Andrzej Zieleniak Katarzyna Cypryk Monika Zurawska-Klis Lucyna A. Wozniak Malgorzata Bukowiecka-Matusiak In the reported study we applied the targeted metabolomic profiling employing high pressure...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7810: The Roles of CCN1/CYR61 in Pulmonary Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21217810 Authors: Yin Zhu Sultan Almuntashiri Yohan Han Xiaoyun Wang Payaningal R. Somanath Duo Zhang CCN1 (cysteine-rich 61, connective tissue growth factor, and nephroblastoma-1), previously named CYR61 (cysteine-rich angiogenic inducer 61) belongs to the CCN family of matricellular proteins. CCN1 plays critical roles in the regulation...
Thu Oct 22, 2020 03:00
IJMS, Vol. 21, Pages 7809: High-Resolution Respirometry Reveals MPP+ Mitochondrial Toxicity Mechanism in a Cellular Model of Parkinson’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms21217809 Authors: Pierpaolo Risiglione Loredana Leggio Salvatore A. M. Cubisino Simona Reina Greta Paternò Bianca Marchetti Andrea Magrì Nunzio Iraci Angela Messina MPP+ is the active metabolite of MPTP, a molecule structurally similar to the herbicide Paraquat,...
Thu Oct 22, 2020 03:00
JCM, Vol. 9, Pages 3392: TAVR, SAVR and MI-AVR. Good Things Come to Those Who Wait Journal of Clinical Medicine doi: 10.3390/jcm9113392 Authors: Antonio Piperata Marco Gemelli Vjola Jorgji Gino Gerosa Tomaso Bottio Modern medicine uses a combination of advanced technology and established knowledge to reach its ultimate goal: healing patients while limiting risks and preventing disease [...]
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JCM, Vol. 9, Pages 3390: Role of the Fatty Acid Binding Proteins in Cardiovascular Diseases: A Systematic Review Journal of Clinical Medicine doi: 10.3390/jcm9113390 Authors: Hien C. Nguyen Mohammad Qadura Krishna K. Singh Cardiovascular diseases (CVD) remain a global pandemic and leading cause of deaths worldwide. While several guidelines have been developed to control the development of CVDs, its prevalence keeps on increasing until this day. Cardiovascular risk factors, such...
Thu Oct 22, 2020 03:00
JCM, Vol. 9, Pages 3391: A Randomized Clinical Trial to Evaluate the Effect of Canephron N in Comparison to Ciprofloxacin in the Prevention of Postoperative Lower Urinary Tract Infections after Midurethral Sling Surgery Journal of Clinical Medicine doi: 10.3390/jcm9113391 Authors: Ewa Rechberger Tomasz Rechberger Sara Wawrysiuk Pawel Miotla Beata Kulik-Rechberger Andrzej Kuszka Andrzej Wróbel Urinary tract infections (UTIs) are one of the most common reasons for antibiotic...
Thu Oct 22, 2020 03:00
JCM, Vol. 9, Pages 3387: Somatic Variant Analysis Identifies Targets for Tailored Therapies in Patients with Vascular Malformations Journal of Clinical Medicine doi: 10.3390/jcm9113387 Authors: Stefano Paolacci Raul Ettore Mattassi Giuseppe Marceddu Elena Manara Alessandra Zulian Giulia Guerri Luca De Antoni Carlo Arduino Daniela Cavalca Matteo Bertelli Vascular malformations include various disorders characterized by morphological, structural and/or functional...
Thu Oct 22, 2020 03:00
JCM, Vol. 9, Pages 3388: Potential Biomarkers in Systemic Sclerosis: A Literature Review and Update Journal of Clinical Medicine doi: 10.3390/jcm9113388 Authors: Utsunomiya Oyama Hasegawa Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by dysregulation of the immune system, vascular damage, and fibrosis of the skin and internal organs. Patients with SSc show a heterogeneous phenotype and a range of clinical courses. Therefore, biomarkers that are helpful...
Thu Oct 22, 2020 03:00
JCM, Vol. 9, Pages 3386: Pediatric Inflammatory Multisystem Syndrome (PIMS) Did Occur in Poland during Months with Low COVID-19 Prevalence, Preliminary Results of a Nationwide Register Journal of Clinical Medicine doi: 10.3390/jcm9113386 Authors: Magdalena Okarska-Napierała Kamila M. Ludwikowska Leszek Szenborn Natalia Dudek Anna Mania Piotr Buda Janusz Książyk Katarzyna Mazur-Malewska Magdalena Figlerowicz Maciej Szczukocki Beata Kucińska Bożena Werner Lidia...
Thu Oct 22, 2020 03:00
JCM, Vol. 9, Pages 3389: Traction Therapy for Cervical Radicular Syndrome is Statistically Significant but not Clinically Relevant for Pain Relief. A Systematic Literature Review with Meta-Analysis and Trial Sequential Analysis Journal of Clinical Medicine doi: 10.3390/jcm9113389 Authors: Claudio Colombo Stefano Salvioli Silvia Gianola Greta Castellini Marco Testa Aim: We aimed to investigate the effectiveness of traction therapy in reducing pain by performing a systematic...
Thu Oct 22, 2020 03:00
JCM, Vol. 9, Pages 3385: Dilated Cardiomyopathy: A Paradigm of Revolution in Medicine Journal of Clinical Medicine doi: 10.3390/jcm9113385 Authors: Marco Merlo Antonio Cannatà Gianfranco Sinagra Dilated Cardiomyopathy (DCM) has a straightforward and apparently “simple” definition: a heart muscle disease characterized by left ventricular (LV) or biventricular dilation and systolic dysfunction in the absence of either pressure or volume overload or coronary artery...
Thu Oct 22, 2020 03:00
JCM, Vol. 9, Pages 3384: Hemodynamic Profiles of Cardiogenic Shock Depending on Their Etiology Journal of Clinical Medicine doi: 10.3390/jcm9113384 Authors: Mélanie Gaubert Marc Laine Noémie Resseguier Nadia Aissaoui Etienne Puymirat Gilles Lemesle Pierre Michelet Sami Hraiech Bruno Lévy Clément Delmas Laurent Bonello The pathophysiology of cardiogenic shock (CS) varies depending on its etiology, which may lead to different hemodynamic profiles (HP) and...
Thu Oct 22, 2020 03:00
JCM, Vol. 9, Pages 3383: Real-World Comparison of Human and Software Image Assessment in Acute Ischemic Stroke Patients’ Qualification for Reperfusion Treatment Journal of Clinical Medicine doi: 10.3390/jcm9113383 Authors: Bartlomiej Lasocha Roman Pulyk Pawel Brzegowy Pawel Latacz Agnieszka Slowik Tadeusz J. Popiela Our aim was to compare human and computer accuracy in reading medical images of acute stroke patients. We analyzed data of patients who underwent assessment...
Thu Oct 22, 2020 03:00
JFMK, Vol. 5, Pages 75: Muscle Synergies Reliability in the Power Clean Exercise Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5040075 Authors: Santos Vaz Correia Valamatos Veloso Pezarat-Correia Muscle synergy extraction has been utilized to investigate muscle coordination in human movement, namely in sports. The reliability of the method has been proposed, although it has not been assessed previously during a complex sportive task. Therefore,...
Thu Oct 22, 2020 03:00
JoF, Vol. 6, Pages 239: Fosmanogepix: A Review of the First-in-Class Broad Spectrum Agent for the Treatment of Invasive Fungal Infections Journal of Fungi doi: 10.3390/jof6040239 Authors: Shaw Ibrahim Fosmanogepix is a first-in-class antifungal currently in Phase 2 clinical trials for the treatment of invasive fungal infections caused by Candida, Aspergillus and rare molds. Fosmanogepix is the N-phosphonooxymethylene prodrug of manogepix, an inhibitor of the fungal enzyme Gwt1....
Thu Oct 22, 2020 03:00
JoF, Vol. 6, Pages 238: Functional Defect of Neutrophils Causing Dermatophytosis: Case Report Journal of Fungi doi: 10.3390/jof6040238 Authors: Rosemeire N. Constantino-Silva Sandro F. Perazzio Nicolas de Albuquerque Weidebach Anete S. Grumach Background: NADPH-oxidase and myeloperoxidase (MPO) play an important role on defense against pathogenic microorganisms. Defects on these mechanisms have been described in association with recurrent infections due to such as Staphylococcus...
Thu Oct 22, 2020 03:00
JoF, Vol. 6, Pages 240: Production of Bio-Based Pigments from Food Processing Industry By-Products (Apple, Pomegranate, Black Carrot, Red Beet Pulps) Using Aspergillus carbonarius Journal of Fungi doi: 10.3390/jof6040240 Authors: Arikan Canli Caro Dufossé Dizge Food processing industry by-products (apple, pomegranate, black carrot, and red beet pulps) were evaluated as raw materials in pigment production by the filamentous fungi Aspergillus carbonarius. The effect of...
Thu Oct 22, 2020 03:00
J. Imaging, Vol. 6, Pages 112: Learning Descriptors Invariance through Equivalence Relations within Manifold: A New Approach to Expression Invariant 3D Face Recognition Journal of Imaging doi: 10.3390/jimaging6110112 Authors: Faisal R. Al-Osaimi This paper presents a unique approach for the dichotomy between useful and adverse variations of key-point descriptors, namely the identity and the expression variations in the descriptor (feature) space. The descriptors variations are learned...
Thu Oct 22, 2020 03:00
JPM, Vol. 10, Pages 186: Hepatic Encephalopathy and Spontaneous Bacterial Peritonitis Improve Cirrhosis Outcome Prediction: A Modified Seven-Stage Model as a Clinical Alternative to MELD Journal of Personalized Medicine doi: 10.3390/jpm10040186 Authors: Huang Tseng Amodio Chen Wang Chang Hsieh Lin Classification of cirrhosis based on clinical stages is rapid and based on five stages at present. Two other relevant events, hepatic encephalopathy (HE) and spontaneous...
Thu Oct 22, 2020 03:00
JPM, Vol. 10, Pages 185: Prognostic Value of CT-Attenuation and 18F-Fluorodeoxyglucose Uptake of Periprostatic Adipose Tissue in Patients with Prostate Cancer Journal of Personalized Medicine doi: 10.3390/jpm10040185 Authors: Jeong Won Lee Youn Soo Jeon Ki Hong Kim Hee Jo Yang Chang Ho Lee Sang Mi Lee This study aimed to assess the prognostic value of computed tomography (CT)-attenuation and 18F-fluorodeoxyglucose (FDG) uptake of periprostatic adipose tissue (PPAT) for...
Thu Oct 22, 2020 03:00
Life, Vol. 10, Pages 249: Function and Benefits of Natural Competence in Cyanobacteria: From Ecology to Targeted Manipulation Life doi: 10.3390/life10110249 Authors: Schirmacher Hanamghar Zedler Natural competence is the ability of a cell to actively take up and incorporate foreign DNA in its own genome. This trait is widespread and ecologically significant within the prokaryotic kingdom. Here we look at natural competence in cyanobacteria, a group of globally distributed oxygenic...
Thu Oct 22, 2020 03:00
Life, Vol. 10, Pages 250: Antioxidant Intervention Attenuates Aging-Related Changes in the Murine Ovary and Oocyte Life doi: 10.3390/life10110250 Authors: Katz-Jaffe Lane Parks McCallie Makloski Schoolcraft Advanced maternal age (AMA) is associated with reduced fertility due in part to diminished ovarian follicle quantity, inferior oocyte quality, chromosome aneuploidy, and lower implantation rates. Ovarian aging is accompanied by increased oxidative stress and blunted...
Thu Oct 22, 2020 03:00
Medicina, Vol. 56, Pages 555: A Novel Fertility Indicator Equation Using Estradiol Levels for Assessment of Phase of the Menstrual Cycle Medicina doi: 10.3390/medicina56110555 Authors: Stephen J. Usala A. Alexandre Trindade Background and Objectives: Urinary hormone home monitoring assays are now available for fertility awareness methods (FAMs) of family planning, but lack sensitivity and precision in establishing the start of the fertile phase. We hypothesized that with a suitable...
Thu Oct 22, 2020 03:00
Membranes, Vol. 10, Pages 301: Effects of 1, 2, 4-Triazole Additive on PEM Fuel Cell Conditioning Membranes doi: 10.3390/membranes10110301 Authors: Nana Zhao Zhiqing Shi Régis Chenitz François Girard Asmae Mokrini Melt processing is one of the essential technologies for the mass production of polymer electrolyte membranes (PEM) at low cost. Azoles have been widely used in PEM to improve their conductivity at a relatively low humidity and recently as bifunctional additives...
Thu Oct 22, 2020 03:00
Membranes, Vol. 10, Pages 302: Augmenting CO2 Absorption Flux through a Gas–Liquid Membrane Module by Inserting Carbon-Fiber Spacers Membranes doi: 10.3390/membranes10110302 Authors: Luke Chen Chii-Dong Ho Li-Yang Jen Jun-Wei Lim Yu-Han Chen We investigated the insertion of eddy promoters into a parallel-plate gas–liquid polytetrafluoroethylene (PTFE) membrane contactor to effectively enhance carbon dioxide absorption through aqueous amine solutions (monoethanolamide—MEA)....
Thu Oct 22, 2020 03:00
Metabolites, Vol. 10, Pages 423: Novel Biomarkers to Distinguish between Type 3c and Type 2 Diabetes Mellitus by Untargeted Metabolomics Metabolites doi: 10.3390/metabo10110423 Authors: Cristina Jimenez-Luna Ariadna Martin-Blazquez Carmelo Dieguez-Castillo Caridad Diaz Jose Luis Martin-Ruiz Olga Genilloud Francisca Vicente Jose Perez del Palacio Jose Prados Octavio Caba Pancreatogenic diabetes mellitus (T3cDM) is a highly frequent complication of pancreatic...
Thu Oct 22, 2020 03:00
Microorganisms, Vol. 8, Pages 1631: Rapid Changes in Microbial Community Structures along a Meandering River Microorganisms doi: 10.3390/microorganisms8111631 Authors: Perrine Cruaud Adrien Vigneron Caetano C. Dorea Manuel J. Rodriguez Steve J. Charette Streams and rivers convey freshwater from lands to the oceans, transporting various organic particles, minerals, and living organisms. Microbial communities are key components of freshwater food webs and take up, utilize,...
Thu Oct 22, 2020 03:00
Microorganisms, Vol. 8, Pages 1629: Effect of a High Proportion of Rye in Compound Feed for Reduction of Salmonella Typhimurium in Experimentally Infected Young Pigs Microorganisms doi: 10.3390/microorganisms8111629 Authors: Bussarakam Chuppava Volker Wilke Clara Berenike Hartung Amr Abd El-Wahab Richard Grone Andreas von Felde Josef Kamphues Christian Visscher Public health concerns and the potential for food-borne zoonotic transmission have made Salmonella a subject...
Thu Oct 22, 2020 03:00
Microorganisms, Vol. 8, Pages 1633: Revisiting an Aspergillus flavus Strain Isolated from an Egyptian Sugarcane Field in 1930 Microorganisms doi: 10.3390/microorganisms8111633 Authors: Mohamed F. Abdallah Kris Audenaert Sarah De Saeger Jos Houbraken The aflatoxin type B and G producer Aspergillus novoparasiticus was described in 2012 and was firstly reported from sputum, hospital air (Brazil), and soil (Colombia). Later, several survey studies reported the occurrence of this...
Thu Oct 22, 2020 03:00
Microorganisms, Vol. 8, Pages 1630: A Multi-Omic Analysis for Low Bone Mineral Density in Postmenopausal Women Suggests a RELATIONSHIP between Diet, Metabolites, and Microbiota Microorganisms doi: 10.3390/microorganisms8111630 Authors: Berenice Palacios-González Eric G. Ramírez-Salazar Berenice Rivera-Paredez Manuel Quiterio Yvonne N. Flores Luis Macias-Kauffer Sofía Moran-Ramos Edgar Denova-Gutiérrez Isabel Ibarra-González Marcela Vela-Amieva Samuel Canizales-Quinteros...
Thu Oct 22, 2020 03:00
Microorganisms, Vol. 8, Pages 1632: Laboratory Diagnosis of Cutaneous and Visceral Leishmaniasis: Current and Future Methods Microorganisms doi: 10.3390/microorganisms8111632 Authors: Juliana Quero Reimão Elizabeth Magiolo Coser Monica Ran Lee Adriano Cappellazzo Coelho Leishmaniasis is a neglected tropical disease with two main clinical forms: cutaneous and visceral leishmaniasis. Diagnosis of leishmaniasis is still a challenge, concerning the detection and correct identification...
Thu Oct 22, 2020 03:00
Microorganisms, Vol. 8, Pages 1628: Extracellular Traps Released by Neutrophils from Cats are Detrimental to Toxoplasma gondii Infectivity Microorganisms doi: 10.3390/microorganisms8111628 Authors: Isabela S. Macedo Marcos V. A. Lima Jéssica S. Souza Natalia C. Rochael Pedro N. Caldas Helene S. Barbosa Flávio A. Lara Elvira M. Saraiva Rafael M. Mariante Toxoplasma gondii is the causative agent of toxoplasmosis, an infectious disease that affects over 30% of the...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4894: Study on Molecular Profiles of Staphylococcus aureus Strains: Spectrometric Approach Molecules doi: 10.3390/molecules25214894 Authors: Michał Złoch Paweł Pomastowski Ewelina Maślak Fernanda Monedeiro Bogusław Buszewski Staphylococcus aureus remains a major health problem responsible for many epidemic outbreaks. Therefore, the development of efficient and rapid methods for studying molecular profiles of S. aureus strains for its further typing...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4893: New Chemical Probe Targeting Bacterial NAD Kinase Molecules doi: 10.3390/molecules25214893 Authors: David A. Clément Clarisse Leseigneur Muriel Gelin Dylan Coelho Valérie Huteau Corinne Lionne Gilles Labesse Olivier Dussurget Sylvie Pochet Nicotinamide adenine dinucleotide (NAD) kinases are essential and ubiquitous enzymes involved in the tight regulation of NAD/nicotinamide adenine dinucleotide phosphate (NADP) levels in many metabolic...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4883: Liquid-Chromatographic Methods for Carboxylic Acids in Biological Samples Molecules doi: 10.3390/molecules25214883 Authors: Takuya Fujiwara Ryoto Inoue Takuma Ohtawa Makoto Tsunoda Carboxyl-bearing low-molecular-weight compounds such as keto acids, fatty acids, and other organic acids are involved in a myriad of metabolic pathways owing to their high polarity and solubility in biological fluids. Various disease areas such as cancer, myeloid leukemia,...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4891: Probiotics in Treatment of Viral Respiratory Infections and Neuroinflammatory Disorders Molecules doi: 10.3390/molecules25214891 Authors: Roghayeh Shahbazi Hamed Yasavoli-Sharahi Nawal Alsadi Nafissa Ismail Chantal Matar Inflammation is a biological response to the activation of the immune system by various infectious or non-infectious agents, which may lead to tissue damage and various diseases. Gut commensal bacteria maintain a symbiotic...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4884: Bioactive Compounds and Total Sugar Contents of Different Open-Pollinated Beetroot Genotypes Grown Organically Molecules doi: 10.3390/molecules25214884 Authors: Khadijeh Yasaminshirazi Jens Hartung Michael Fleck Simone Graeff-Hoenninger The growing interest of consumers in healthy organic products has increased the attention to the organic production of beetroot. In this regard, six field experiments were conducted in 2017 and 2018 in three different...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4890: Advances in Azorella glabra Wedd. Extract Research: In Vitro Antioxidant Activity, Antiproliferative Effects on Acute Myeloid Leukemia Cells and Bioactive Compound Characterization Molecules doi: 10.3390/molecules25214890 Authors: Daniela Lamorte Immacolata Faraone Ilaria Laurenzana Stefania Trino Daniela Russo Dilip K. Rai Maria Francesca Armentano Pellegrino Musto Alessandro Sgambato Luciana De Luca Luigi Milella Antonella...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4889: Target and Suspect HRMS Metabolomics for the Determination of Functional Ingredients in 13 Varieties of Olive Leaves and Drupes from Greece Molecules doi: 10.3390/molecules25214889 Authors: Evangelia Kritikou Natasa P. Kalogiouri Lydia Kolyvira Nikolaos S. Thomaidis The huge interest in the health-related properties of foods to improve health has brought about the development of sensitive analytical methods for the characterization of natural...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4888: Subcellular Location of Tirapazamine Reduction Dramatically Affects Aerobic but Not Anoxic Cytotoxicity Molecules doi: 10.3390/molecules25214888 Authors: Chris P. Guise Maria R. Abbattista Robert F. Anderson Dan Li Rana Taghipouran Angela Tsai Su Jung Lee Jeff B. Smaill William A. Denny Michael P. Hay William R. Wilson Kevin O. Hicks Adam V. Patterson Hypoxia is an adverse prognostic feature of solid cancers that may...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4887: Replacing Synthetic Ingredients by Sustainable Natural Alternatives: A Case Study Using Topical O/W Emulsions Molecules doi: 10.3390/molecules25214887 Authors: Sara Bom Manuel Fitas Ana Margarida Martins Pedro Pinto Helena Margarida Ribeiro Joana Marto With the increasing debate on sustainability, there is a strong market trend to formulate more sustainable products for topical application. Several studies emphasize the potential applications...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4881: Surface Adsorption Properties and Layer Structures of Homogeneous Polyoxyethylene-Type Nonionic Surfactants in Quaternary-Ammonium-Salt-Type Amphiphilic Gemini Ionic Liquids with Oxygen- or Nitrogen-Containing Spacers Molecules doi: 10.3390/molecules25214881 Authors: Risa Kawai Maiko Niki Shiho Yada Tomokazu Yoshimura The amphiphilic ionic liquids containing an alkyl chain in molecules form nano-structure in the bulk, although they also show surface...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4892: Discovery of Novel 3-Cyanopyridines as Survivin Modulators and Apoptosis Inducers Molecules doi: 10.3390/molecules25214892 Authors: Rehab Sabour Marwa F. Harras Omkulthom Mohamed Al Kamaly Najla Altwaijry The overexpression of survivin is usually accompanied by an increased resistance of cancer cells to chemotherapeutic agents in addition to cancer aggressiveness. Consequently, survivin is considered as an attractive target to develop new promising...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4885: Optimized Nb-Based Zeolites as Catalysts for the Synthesis of Succinic Acid and FDCA Molecules doi: 10.3390/molecules25214885 Authors: Magdi El El Fergani Natalia Candu Madalina Tudorache Pascal Granger Vasile I. Parvulescu Simona M. Coman Nb(0.05 moles%)-zeolites prepared via a post synthesis methodology (BEA, Y, ZSM-5), or a direct sol-gel method (Silicalite-1) were investigated in the hydroxymethylfurfural (HMF) oxidation by both molecular...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4877: Trifluoromethanesulfonamide vs. Non-Fluorinated Sulfonamides in Oxidative Sulfamidation of the C=C Bond: An In Silico Study Molecules doi: 10.3390/molecules25214877 Authors: Anton V. Kuzmin Mikhail Yu. Moskalik Bagrat A. Shainyan A theoretical analysis of the reaction of oxidative sulfamidation of several alkenes was performed in order to explain the various experimental observations and different reactivity of triflamide and non-fluorinated sulfonamides....
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4882: The Budesonide-Hydroxypropyl-β-Cyclodextrin Complex Attenuates ROS Generation, IL-8 Release and Cell Death Induced by Oxidant and Inflammatory Stress. Study on A549 and A-THP-1 Cells Molecules doi: 10.3390/molecules25214882 Authors: Jules César Bayiha Brigitte Evrard Didier Cataldo Pascal De De Tullio Marie-Paule Mingeot-Leclercq Synthetic glucocorticoids such as budesonide (BUD) are potent anti-inflammatory drugs commonly used to treat patients...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4879: Identification of a Novel Pyrrole Alkaloid from the Edible Mushroom Basidiomycetes-X (Echigoshirayukidake) Molecules doi: 10.3390/molecules25214879 Authors: Toshio Sakamoto Ayaka Nishida Naoki Wada Yutaka Nakamura Shinji Sato Tetsuya Konishi Seiichi Matsugo Three pyrrole alkaloid derivatives were isolated from the edible mushroom Basidiomycetes-X (Echigoshirayukidake) by water extraction followed by ethyl acetate fractionation. The chemical...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4875: Design of Metal-Organic Framework Templated Materials Using High-Throughput Computational Screening Molecules doi: 10.3390/molecules25214875 Authors: Momin Ahmad Yi Luo Christof Wöll Manuel Tsotsalas Alexander Schug The ability to crosslink Metal-Organic Frameworks (MOFs) has recently been discovered as a flexible approach towards synthesizing MOF-templated “ideal network polymers”. Crosslinking MOFs with rigid cross-linkers...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4886: Renewable Polysaccharides Micro/Nanostructures for Food and Cosmetic Applications Molecules doi: 10.3390/molecules25214886 Authors: Alessio Massironi Andrea Morelli Dario Puppi Federica Chiellini The worldwide diffusion of nanotechnologies into products nowadays has completely revolutionized human life, providing novel comfort and benefits. Their inclusion in food and cosmetic has a heavy impact over the market, allowing the development of higher...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4878: Bioactive Natural Antivirals: An Updated Review of the Available Plants and Isolated Molecules Molecules doi: 10.3390/molecules25214878 Authors: Syam Mohan Manal Mohamed Elhassan Taha Hafiz A. Makeen Hassan A. Alhazmi Mohammed Al Bratty Shahnaz Sultana Waquar Ahsan Asim Najmi Asaad Khalid Viral infections and associated diseases are responsible for a substantial number of mortality and public health problems around the world. Each...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4876: Exopolysaccharide II Is Relevant for the Survival of Sinorhizobium meliloti under Water Deficiency and Salinity Stress Molecules doi: 10.3390/molecules25214876 Authors: Emiliano Primo Pablo Bogino Sacha Cossovich Emiliano Foresto Fiorela Nievas Walter Giordano Sinorhizobium meliloti is a soil bacterium of great agricultural importance because of its ability to fix atmospheric nitrogen in symbiotic association with alfalfa (Medicago sativa)...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4880: Drying Shrinkage of Concrete Containing Calcium Stearate, (Ca(C18H35O2)2), with Ordinary Portland Cement (OPC) as a Binder: Experimental and Modelling Studies Molecules doi: 10.3390/molecules25214880 Authors: Agus Maryoto Rachmad Setijadi Arnie Widyaningrum Sugeng Waluyo This work investigates the effect of calcium stearate (Ca(C18H35O2)2) on concrete shrinkage behaviors by using experimental testing. The test specimens are cubes with each dimension...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4874: Enhancement of Phthalocyanine Mediated Photodynamic Therapy by Catechin on Lung Cancer Cells Molecules doi: 10.3390/molecules25214874 Authors: Giftson J. Senapathy Blassan P. George Heidi Abrahamse Worldwide, lung cancer remains one of the leading cancers with increasing mortality rates. Though chemotherapy for lung cancer is effective, it is always accompanied by unavoidable and grave side effects. Photodynamic therapy (PDT), using novel photosensitizers,...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4872: Benzobicyclo[3.2.1]octene Derivatives as a New Class of Cholinesterase Inhibitors Molecules doi: 10.3390/molecules25214872 Authors: Čadež Grgičević Ahmetović Barić Hrvat Kovarik Škorić A library of amine, oxime, ether, epoxy and acyl derivatives of the benzobicyclo[3.2.1]octene were synthesized and evaluated as inhibitors of both human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The majority of the tested compounds...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4873: Essential Oils from Monarda fistulosa: Chemical Composition and Activation of Transient Receptor Potential A1 (TRPA1) Channels Molecules doi: 10.3390/molecules25214873 Authors: Monica Ghosh Igor A. Schepetkin Gulmira Özek Temel Özek Andrei I. Khlebnikov Derek S. Damron Mark T. Quinn Little is known about the pharmacological activity of Monarda fistulosa L. essential oils. To address this issue, we isolated essential oils from the flowers...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4871: MH-ICP-MS Analysis of the Freshwater and Saltwater Environmental Resources of Upolu Island, Samoa Molecules doi: 10.3390/molecules25214871 Authors: Sasan Rabieh Odmaa Bayaraa Emarosa Romeo Patila Amosa Khemet Calnek Youssef Idaghdour Michael A. Ochsenkühn Shady A. Amin Gary Goldstein Timothy G. Bromage The elemental composition of freshwater and saltwater samples around the South Pacific island of Upolu, Samoa has been investigated...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4870: Topical Wound Healing Activity of Myricetin Isolated from Tecomaria capensis v. aurea Molecules doi: 10.3390/molecules25214870 Authors: Abdelsamed I. Elshamy Naglaa M. Ammar Heba A. Hassan Walaa A. El-Kashak Salim S. Al-Rejaie Ahmed M. Abd-ElGawad Abdel-Razik H. Farrag Wounds and burn injury are major causes of death and disability worldwide. Myricetin is a common bioactive flavonoid isolated naturally from the plant kingdom. Herein,...
Thu Oct 22, 2020 03:00
Molecules, Vol. 25, Pages 4869: Recent Materials Developed for Dispersive Solid Phase Extraction Molecules doi: 10.3390/molecules25214869 Authors: Ścigalski Kosobucki Solid phase extraction (SPE) is an analytical procedure developed with the purpose of separating a target analyte from a complex sample matrix prior to quantitative or qualitative determination. The purpose of such treatment is twofold: elimination of matrix constituents that could interfere with the detection process...
Thu Oct 22, 2020 03:00
MTI, Vol. 4, Pages 76: Innovative and Assistive eHealth Technologies for Smart Therapeutic and Rehabilitation Outdoor Spaces for the Elderly Demographic Multimodal Technologies and Interaction doi: 10.3390/mti4040076 Authors: Bruno Marques Jacqueline McIntosh Alvin Valera Anuroop Gaddam The use of technology for social connectivity and achieving engagement goals is increasingly essential to the overall well-being of our rapidly ageing population. While much of the extant literature...
Thu Oct 22, 2020 03:00
MTI, Vol. 4, Pages 75: Virtual Reality Nature Exposure and Test Anxiety Multimodal Technologies and Interaction doi: 10.3390/mti4040075 Authors: Alison O’Meara Marica Cassarino Aaron Bolger Annalisa Setti The number of students affected by exam anxiety continues to rise. Therefore, it is becoming progressively relevant to explore innovative remediation strategies that will help mitigate the debilitating effects of exam anxiety. The study aimed to investigate whether green environment...
Thu Oct 22, 2020 03:00
Nanomaterials, Vol. 10, Pages 2097: Morphology and Mechanical Properties of 3Y-TZP Nanofiber Mats Nanomaterials doi: 10.3390/nano10112097 Authors: Alexander I. Tyurin Vyacheslav V. Rodaev Svetlana S. Razlivalova Viktor V. Korenkov Andrey O. Zhigachev Vladimir M. Vasyukov Yuri I. Golovin The mats of yttria-stabilized tetragonal zirconia nanofibers were prepared using electrospinning. The effect of calcination temperature in the range of 600–1200 °C...
Thu Oct 22, 2020 03:00
Nanomaterials, Vol. 10, Pages 2096: Efficient Photocatalytic Hydrogen Evolution over TiO2-X Mesoporous Spheres-ZnO Nanorods Heterojunction Nanomaterials doi: 10.3390/nano10112096 Authors: Zhang Li Wang Wang Jiang Jiao Liu Zeng Zhao Liu Xun Fang Gao Zhang Zhao Photocatalytic water splitting into hydrogen is regarded as one of the key solutions to the deterioration of the global environment and energy. Due to the significantly reduced...
Thu Oct 22, 2020 03:00
Nanomaterials, Vol. 10, Pages 2094: Triplet Energy Transfer Mechanism of Ternary Organic Hybrid Thin Films of PFO/MEH-PPV/CsPbBr3 Perovskite Quantum Dots Nanomaterials doi: 10.3390/nano10112094 Authors: Bandar Ali Al-Asbahi Saif M. H. Qaid Hamid M. Ghaithan Abdullah S. Aldwayyan The triplet energy transfer mechanism of novel poly(9,9-di-n-octylflourenyl-2,7-diyl) (PFO)/poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV)/CsPbBr3 perovskite quantum dot (PQD) hybrid...
Thu Oct 22, 2020 03:00
Nanomaterials, Vol. 10, Pages 2095: Analog and Digital Bipolar Resistive Switching in Co–Al-Layered Double Hydroxide Memristor Nanomaterials doi: 10.3390/nano10112095 Authors: Yanmei Sun Li Li Keying Shi We demonstrate a nonvolatile memristor based on Co–Al-layered double hydroxide (Co–Al LDH). We also introduce a memristor that has a hexazinone-adsorbing Co–Al LDH composite active layer. Memristor characteristics could be modulated by adsorbing hexazinone with Co–Al LDHs in the...
Thu Oct 22, 2020 03:00
Nanomaterials, Vol. 10, Pages 2092: Spin Caloritronics in 3D Interconnected Nanowire Networks Nanomaterials doi: 10.3390/nano10112092 Authors: Tristan da Câmara Santa Clara Gomes Nicolas Marchal Flavio Abreu Araujo Luc Piraux Recently, interconnected nanowire networks have been found suitable as flexible macroscopic spin caloritronic devices. The 3D nanowire networks are fabricated by direct electrodeposition in track-etched polymer templates with crossed nano-channels. This...
Thu Oct 22, 2020 03:00
Nanomaterials, Vol. 10, Pages 2091: Enhanced Desalination Performance of Capacitive Deionization Using Nanoporous Carbon Derived from ZIF-67 Metal Organic Frameworks and CNTs Nanomaterials doi: 10.3390/nano10112091 Authors: Phuoc Jung Tran Lee Yoo Kang Cho Capacitive deionization (CDI) based on ion electrosorption has recently emerged as a promising desalination technology due to its low energy consumption and environmental friendliness compared to conventional...
Thu Oct 22, 2020 03:00
Nanomaterials, Vol. 10, Pages 2093: Tuning Porosity of Reduced Graphene Oxide Membrane Materials by Alkali Activation Nanomaterials doi: 10.3390/nano10112093 Authors: Shen Maurizi Magnacca Boffa Yue The alkali-activation method allows for obtaining highly porous carbon materials. In this study, we explored the effect of activation temperature and potassium hydroxide concentration on the pore structure of reduced graphene oxide (rGO), as potential membrane material. Above...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3230: A Review of Nutrition Support Guidelines for Individuals with or Recovering from COVID-19 in the Community Nutrients doi: 10.3390/nu12113230 Authors: Abbie L. Cawood Emily R. Walters Trevor R. Smith Rachel H. Sipaul Rebecca J. Stratton COVID-19 negatively impacts nutritional status and as such identification of nutritional risk and consideration of the need for nutrition support should be fundamental in this patient group. In recent months,...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3236: Edible Oxya chinensis sinuosa-Derived Protein as a Potential Nutraceutical for Anticancer Immunity Improvement Nutrients doi: 10.3390/nu12113236 Authors: Woo Sik Kim Jeong Moo Han Ha-Yeon Song Eui-Hong Byun Ho Seong Seo Eui-Baek Byun Oxya chinensis sinuosa (Ocs) is consumed as representative edible insects in Asia, but its function in various immune systems remains unclear. This study aimed to demonstrate the immunomodulatory effect, particularly...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3237: Efficacy and Safety of Kudzu Flower–Mandarin Peel on Hot Flashes and Bone Markers in Women during the Menopausal Transition: A Randomized Controlled Trial Nutrients doi: 10.3390/nu12113237 Authors: Kim Jeong Hur Lee Kwon This randomized controlled study aimed to assess the efficacy and safety of an extract mixture of kudzu flower and mandarin peel (KM) on hot flashes (HFs) and markers of bone turnover in women during the menopausal transition....
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3234: Dietary Options for Rodents in the Study of Obesity Nutrients doi: 10.3390/nu12113234 Authors: Bastías-Pérez Serra Herrero Obesity and its associated metabolic diseases are currently a priority research area. The increase in global prevalence at different ages is having an enormous economic and health impact. Genetic and environmental factors play a crucial role in the development of obesity, and diet is one of the main factors that contributes...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3235: Animal and Cellular Studies Demonstrate Some of the Beneficial Impacts of Herring Milt Hydrolysates on Obesity-Induced Glucose Intolerance and Inflammation Nutrients doi: 10.3390/nu12113235 Authors: Rachel Durand Adia Ouellette Vanessa P. Houde Frédéric Guénard Thibaut V. Varin Bruno Marcotte Geneviève Pilon Erwann Fraboulet Marie-Claude Vohl André Marette Laurent Bazinet The search for bioactive compounds from enzymatic hydrolysates...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3233: Exercise and Nutrition Interventions in Patients with Head and Neck Cancer during Curative Treatment: A Systematic Review and Meta-Analysis Nutrients doi: 10.3390/nu12113233 Authors: Bye Sandmael Stene Thorsen Balstad Solheim Pripp Oldervoll The aim of this meta-analysis was to examine the effects of nutritional and physical exercise interventions and interventions combining these interventions during radiotherapy treatment...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3232: Diet Quality, Saturated Fat and Metabolic Syndrome Nutrients doi: 10.3390/nu12113232 Authors: Stéphanie Harrison Patrick Couture Benoît Lamarche Indices reflecting overall diet quality are used globally in research to predict the risk of various diseases and metabolic disorders such as metabolic syndrome (MetS). Such indices are built to measure adherence to current dietary guidelines or to best assess the diet–disease relationship. Although...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3231: Associations of Early Parental Concerns and Feeding Behaviors with Child’s Diet Quality through Mid-Childhood Nutrients doi: 10.3390/nu12113231 Authors: Gingras Switkowski Rifas-Shiman Faleschini Oken Hivert Parental feeding practices have been associated with children’s dietary intakes, yet the directionality of these associations remains unclear. Among 1172 mother-child pairs from Project Viva, we aimed to examine associations...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3229: Associations of Ultra-Processed and Unprocessed/Minimally Processed Food Consumption with Peripheral and Central Hemodynamics, and Arterial Stiffness in Young Healthy Adults Nutrients doi: 10.3390/nu12113229 Authors: Smiljanec Mbakwe Ramos-Gonzalez Mesbah Lennon Consumption of ultra-processed food (UPF) replaces the intake of freshly prepared unprocessed/minimally processed food (MPF) and is positively associated with hypertension and...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3228: Time-Restricted Eating as a Nutrition Strategy for Individuals with Type 2 Diabetes: A Feasibility Study Nutrients doi: 10.3390/nu12113228 Authors: Evelyn B. Parr Brooke L. Devlin Karen H. C. Lim Laura N. Z. Moresi Claudia Geils Leah Brennan John A. Hawley Individuals with type 2 diabetes (T2D) require a long-term dietary strategy for blood glucose management and may benefit from time-restricted eating (TRE, where the duration between...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3227: The Legacy Effect in the Prevention of Cardiovascular Disease Nutrients doi: 10.3390/nu12113227 Authors: Esther Viñas Esmel José Naval Álvarez Emilio Sacanella Meseguer The “legacy effect” describes the long-term benefits that may persist for many years after the end of an intervention period, involving different biological processes. The legacy effect in cardiovascular disease (CVD) prevention has been evaluated by a limited...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3226: Association Between Diet Quality and Cardiorespiratory Fitness in Korean Adults: The 2014–2015 National Fitness Award Project Nutrients doi: 10.3390/nu12113226 Authors: Mingyeong Seong Youjin Kim Saejong Park Hyesook Kim Oran Kwon Cardiorespiratory fitness (CRF) is a strong and meaningful indicator for predicting mortality, including cardiovascular disease, as well as simple physical capacity. Healthy eating is thought to be one of the crucial...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3225: Prebiotic Xylo-Oligosaccharides Ameliorate High-Fat-Diet-Induced Hepatic Steatosis in Rats Nutrients doi: 10.3390/nu12113225 Authors: Sanna Lensu Raghunath Pariyani Elina Mäkinen Baoru Yang Wisam Saleem Eveliina Munukka Maarit Lehti Anastasiia Driuchina Jere Lindén Marja Tiirola Leo Lahti Satu Pekkala Understanding the importance of the gut microbiota (GM) in non-alcoholic fatty liver disease (NAFLD) has raised the hope...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3224: Antioxidant Activity with Increased Endogenous Levels of Vitamin C, E and A Following Dietary Supplementation with a Combination of Glutathione and Resveratrol Precursors Nutrients doi: 10.3390/nu12113224 Authors: Priscilla Biswas Cinzia Dellanoce Alessandra Vezzoli Simona Mrakic-Sposta Mauro Malnati Alberto Beretta Roberto Accinni The effects of two different dietary supplements on the redox status of healthy human participants were...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3223: Dietary Plant-Origin Bio-Active Compounds, Intestinal Functionality, and Microbiome Nutrients doi: 10.3390/nu12113223 Authors: Elad Tako In recent years, plant-origin bio-active compounds in foods (staple crops, fruit, vegetables, and others) have been gaining interest, and processes to consider them for public health recommendations are being presented and discussed in the literature. However, at times, it may be challenging to demonstrate causality,...
Thu Oct 22, 2020 03:00
Nutrients, Vol. 12, Pages 3222: Association between Polyunsaturated Fatty Acid and Reactive Oxygen Species Production of Neutrophils in the General Population Nutrients doi: 10.3390/nu12113222 Authors: Nobuaki Suzuki Kaori Sawada Ippei Takahashi Motoko Matsuda Shinji Fukui Hidemasa Tokuyasu Hiroyasu Shimizu Junichi Yokoyama Arata Akaike Shigeyuki Nakaji Little is known about the relationship between polyunsaturated fatty acids (PUFAs) and reactive oxygen species...
Thu Oct 22, 2020 03:00
Pathogens, Vol. 9, Pages 868: Human Campylobacteriosis Cases Traceable to Chicken Meat—Evidence for Disseminated Outbreaks in Finland Pathogens doi: 10.3390/pathogens9110868 Authors: Ann-Katrin Llarena Rauni Kivistö Campylobacter jejuni (C. jejuni) is the most common cause of human bacterial gastroenteritis in the world. Food-borne campylobacteriosis is thought to be commonly caused by the handling and consumption of undercooked chicken meat, but the epidemiology of this disease is...
Thu Oct 22, 2020 03:00
Pathogens, Vol. 9, Pages 866: Geographical Distribution of Borrelia burgdorferi sensu lato in Ticks Collected from Wild Rodents in the Republic of Korea Pathogens doi: 10.3390/pathogens9110866 Authors: Kim Kim Kim Lee : Lyme disease is a tick-borne zoonotic disease caused by Borrelia burgdorferi sensu lato (s. l.) via transmission cycles involving competent tick vectors and vertebrate reservoirs. Here, we determined the prevalence and distribution of Borrelia genospecies...
Thu Oct 22, 2020 03:00
Pathogens, Vol. 9, Pages 863: A Novel Bead-Based Immunoassay for the Measurement of Heat Shock Proteins 27 and 70 Pathogens doi: 10.3390/pathogens9110863 Authors: Njemini Verhaeghen Mets Weets Bautmans Heat shock proteins (HSPs) play an essential role in protecting proteins from denaturation and are implicated in diverse pathophysiological conditions like cardiovascular diseases, cancer, infections, and neurodegenerative diseases. Scientific evidence indicates that if...
Thu Oct 22, 2020 03:00
Pathogens, Vol. 9, Pages 864: Occurrence, Pathogenicity, and Mycotoxin Production of Fusarium temperatum in Relation to Other Fusarium Species on Maize in Germany Pathogens doi: 10.3390/pathogens9110864 Authors: Pfordt Schiwek Rathgeb Rodemann Bollmann Buchholz Karlovsky von Tiedemann : Fusarium subglutinans is a plant pathogenic fungus infecting cereal grain crops. In 2011, the species was divided in Fusarium temperatum sp. nov. and F. subglutinans sensu...
Thu Oct 22, 2020 03:00
Pathogens, Vol. 9, Pages 865: Fusion of Dendritic Cells Activating Rv2299c Protein Enhances the Protective Immunity of Ag85B-ESAT6 Vaccine Candidate against Tuberculosis Pathogens doi: 10.3390/pathogens9110865 Authors: Yong Woo Back Hyun Shik Bae Han-Gyu Choi Dang Thi Binh Yeo-Jin Son Seunga Choi Hwa-Jung Kim In Mycobacterium tuberculosis infection, naïve T cells that encounter mycobacterial antigens through dendritic cells (DCs) induce various CD4+ T-cell...
Thu Oct 22, 2020 03:00
Pathogens, Vol. 9, Pages 867: Listeria monocytogenes Infection of Bat Pipistrellus nathusii Epithelial cells Depends on the Invasion Factors InlA and InlB Pathogens doi: 10.3390/pathogens9110867 Authors: Povolyaeva Chalenko Kalinin Kolbasova Pivova Kolbasov Yurkov Ermolaeva L. monocytogenes is a widespread facultative intracellular pathogen. The range of natural hosts that supporting L. monocytogenes persistence in the environment has not been fully established...
Thu Oct 22, 2020 03:00
Pathogens, Vol. 9, Pages 862: Characterization of Legionella pneumophila Populations by Multilocus Variable Number of Tandem Repeats (MLVA) Genotyping from Drinking Water and Biofilm in Hospitals from Different Regions of the West Bank Pathogens doi: 10.3390/pathogens9110862 Authors: Ashraf R. Zayed Marina Pecellin Alaa Salah Hanna Alalam Suha Butmeh Michael Steinert Rene Lesnik Ingrid Brettar Manfred G. Höfle Dina M. Bitar The West Bank can be considered a...
Thu Oct 22, 2020 03:00
Pathogens, Vol. 9, Pages 861: Effects of Taenia Pisiformis Infection and Obesity on Clinical Parameters, Organometry and Fat Distribution in Male Rabbits Pathogens doi: 10.3390/pathogens9110861 Authors: David Arias-Hernández Sara García-Jiménez Rosa Domínguez-Roldan Clara Murcia-Mejía Armida Báez-Saldaña Claudia Hallal-Calleros Ivan Flores-Pérez Taenia pisiformis infection causes important economic loss in farms. It is suggested that obesity has a major impact on infection...
Thu Oct 22, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 330: Regioselective Hydroxylation of Phloretin, a Bioactive Compound from Apples, by Human Cytochrome P450 Enzymes Pharmaceuticals doi: 10.3390/ph13110330 Authors: Nguyen Cao Nguyen Le Cha Choi Pan Yeom Kang Yun Phloretin, the major polyphenol compound in apples and apple products, is interesting because it shows beneficial effects on human health. It is mainly found as a form of glucoside, phlorizin. However, the metabolic...
Thu Oct 22, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 328: Attenuation of Oxidative Stress by Cannabinoids and Cannabis Extracts in Differentiated Neuronal Cells Pharmaceuticals doi: 10.3390/ph13110328 Authors: Raja Ahmadi de Costa Li Kerman In this proof-of-concept study, the antioxidant activity of phytocannabinoids, namely cannabidiol (CBD) and Δ9- tetrahydrocannabinol (THC), were investigated using an in vitro system of differentiated human neuronal SY-SH5Y cells. The oxidative...
Thu Oct 22, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 329: Gel-Based Nanocarrier for Intravesical Chemotherapy Delivery: In Vitro and In Vivo Study Pharmaceuticals doi: 10.3390/ph13110329 Authors: Ting-Yu Chen Ming-Jun Tsai I-Ling Lin Li-Ching Chang Pao-Chu Wu Intravesical administration of chemotherapeutic agents can enhance drug accumulation in tumors and reduce systemic side effects. Nanocarriers were developed for intravesical administration and exploit the permeation enhancement effect. In...
Thu Oct 22, 2020 03:00
Pharmaceutics, Vol. 12, Pages 1004: Fluorescent Dye Labeling Changes the Biodistribution of Tumor-Targeted Nanoparticles Pharmaceutics doi: 10.3390/pharmaceutics12111004 Authors: Álamo Pallarès Céspedes Falgàs Sanchez Serna Sánchez-García Voltà-Duràn Morris Sánchez-Chardi Casanova Mangues Vazquez Villaverde Unzueta Fluorescent dye labeling is a common strategy to analyze the fate of administered nanoparticles in living organisms....
Thu Oct 22, 2020 03:00
Pharmaceutics, Vol. 12, Pages 1003: Recombinant Myxoma Virus-Derived Immune Modulator M-T7 Accelerates Cutaneous Wound Healing and Improves Tissue Remodeling Pharmaceutics doi: 10.3390/pharmaceutics12111003 Authors: Yaron Zhang Guo Awo Burgin Schutz Zhang Kilbourne Daggett-Vondras Lowe Lucas Complex dermal wounds represent major medical and financial burdens, especially in the context of comorbidities such as diabetes, infection and advanced age....
Thu Oct 22, 2020 03:00
Pharmaceutics, Vol. 12, Pages 1008: Enhanced Water Solubility and Oral Bioavailability of Paclitaxel Crystal Powders through an Innovative Antisolvent Precipitation Process: Antisolvent Crystallization Using Ionic Liquids as Solvent Pharmaceutics doi: 10.3390/pharmaceutics12111008 Authors: Qilei Yang Chang Zu Wengang Li Weiwei Wu Yunlong Ge Lingling Wang Li Wang Yong Li Xiuhua Zhao Paclitaxel (PTX) is a poor water-soluble antineoplastic drug with significant antitumor...
Thu Oct 22, 2020 03:00
Pharmaceutics, Vol. 12, Pages 1006: Recent Advances in Extracellular Vesicles as Drug Delivery Systems and Their Potential in Precision Medicine Pharmaceutics doi: 10.3390/pharmaceutics12111006 Authors: de Jong Barros Hoenderop Rigalli Extracellular vesicles (EVs) are membrane-bilayered nanoparticles released by most cell types. Recently, an enormous number of studies have been published on the potential of EVs as carriers of therapeutic agents. In contrast to systems such...
Thu Oct 22, 2020 03:00
Pharmaceutics, Vol. 12, Pages 1009: Target-Mediated Brain Tissue Binding for Small Molecule Inhibitors of Heat Shock Protein 90 Pharmaceutics doi: 10.3390/pharmaceutics12111009 Authors: Lassina Badolo Kenneth Thirstrup Søren Møller Nielsen Ask Püschl Thomas Jensen Steve Watson Christoffer Bundgaard Drug distribution in the brain is generally associated with an affinity for fatty brain tissues and therefore known to be species- and concentration-independent. We report...
Thu Oct 22, 2020 03:00
Pharmaceutics, Vol. 12, Pages 1005: Generation of a hTERT-Immortalized Human Sertoli Cell Model to Study Transporter Dynamics at the Blood-Testis Barrier Pharmaceutics doi: 10.3390/pharmaceutics12111005 Authors: Raymond K. Hau Siennah R. Miller Stephen H. Wright Nathan J. Cherrington The blood-testis barrier (BTB) formed by adjacent Sertoli cells (SCs) limits the entry of many chemicals into seminiferous tubules. Differences in rodent and human substrate-transporter selectivity...
Thu Oct 22, 2020 03:00
Pharmaceutics, Vol. 12, Pages 1001: Continuous-Flow Production of Liposomes with a Millireactor under Varying Fluidic Conditions Pharmaceutics doi: 10.3390/pharmaceutics12111001 Authors: Yanar Mosayyebi Nastruzzi Carugo Zhang Continuous-flow production of liposomes using microfluidic reactors has demonstrated advantages compared to batch methods, including greater control over liposome size and size distribution and reduced reliance on post-production processing steps....
Thu Oct 22, 2020 03:00
Pharmaceutics, Vol. 12, Pages 1002: Development of Remdesivir as a Dry Powder for Inhalation by Thin Film Freezing Pharmaceutics doi: 10.3390/pharmaceutics12111002 Authors: Sahakijpijarn Moon Koleng Christensen Williams III Remdesivir exhibits in vitro activity against SARS-CoV-2 and was granted approval for emergency use. To maximize delivery to the lungs, we formulated remdesivir as a dry powder for inhalation using thin film freezing (TFF). TFF produces brittle matrix...
Thu Oct 22, 2020 03:00
Pharmaceutics, Vol. 12, Pages 1007: Hyperthermia and Temperature-Sensitive Nanomaterials for Spatiotemporal Drug Delivery to Solid Tumors Pharmaceutics doi: 10.3390/pharmaceutics12111007 Authors: Mohamadreza Amin Wenqiu Huang Ann L. B. Seynhaeve Timo L. M. ten Hagen Nanotechnology has great capability in formulation, reduction of side effects, and enhancing pharmacokinetics of chemotherapeutics by designing stable or long circulating nano-carriers. However, effective drug delivery...
Thu Oct 22, 2020 03:00
Pharmacy, Vol. 8, Pages 194: Lockdown, Emotional Intelligence, Academic Engagement and Burnout in Pharmacy Students during the Quarantine Pharmacy doi: 10.3390/pharmacy8040194 Authors: Moreno-Fernandez Ochoa Lopez-Aliaga Alferez Gomez-Guzman Lopez-Ortega Diaz-Castro The recent appearance and rapid spread of the new SARS-CoV-2 coronavirus meant taking unprecedented measures to control the pandemic, which in Spain forced a state of alarm and a very strict confinement,...
Thu Oct 22, 2020 03:00
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