Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης

“Place, Not Race”: A Focus on Neighborhood as a Risk Factor for Hospitalizations in Patients Receiving Maintenance Hemodialysis

Major metropolitan cities in the United States commonly publish data related to neighborhood racial segregation and social determinants of health. For example, the Boston Public Health Commission consistently reports that Boston neighborhoods with a majority of Black residents have lower rates of educational attainment, higher unemployment rates, and a higher percentage of the population that live below the federal poverty line compared with other neighborhoods of different racial composition.1 These...

The Evolving Role of Novel Biomarkers in Glomerular Disease: A Review

Recent advances in glomerular biology have expanded our understanding of glomerular diseases, leading to more precise therapeutic options. Since the discovery of the autoantigen phospholipase A2 receptor in primary membranous nephropathy 10 years ago, the serologic evaluation of glomerular diseases has become more detailed and nuanced for nephrologists. In addition to phospholipase A2 receptor antibodies, circulating autoantibodies now include thrombospondin type 1 domain–containing 7A and most recently,...

Plant-Based Diets for Kidney Disease: A Guide for Clinicians

In recent years, a growing body of evidence has emerged on the benefits of plant-based diets on the prevention and treatment of lifestyle diseases. In parallel, data now exist regarding the treatment of chronic kidney disease (CKD) and its most common complications with this dietary pattern. Improving the nutrient quality of patients by including a higher proportion of plant-based foods while reducing total – and animal protein – intake may reduce the need for – or complement – nephroprotective medications,...

Variation in Best Practice Measures in Patients With Severe Hospital-Acquired Acute Kidney Injury: A Multicenter Study

To the Editor:

Strategies to Treat Obesity in Patients With CKD

Obesity prevalence continues to increase worldwide, accompanied by a rising tide of hypertension, diabetes, and chronic kidney disease (CKD). While body mass index is typically used to assess obesity in clinical practice, altered body composition (e.g. reduced muscle mass, increased visceral adiposity) are common among patients with CKD. Weight loss achieved through behavioral modification or medications reduces albuminuria, and in some cases, slows decline in estimated glomerular filtration rate...

American Thyroid Association

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Thyroid Health Blog: Finally – Some Progress in Anaplastic Thyroid Cancer

Jochen Lorch Harvard Medical School, Boston, MA October 16, 2020 Anaplastic or undifferentiated thyroid cancer is a rare but extremely deadly form of thyroid cancer. It constitutes only 1-2% of thyroid cancer cases but accounts for over 30% of thyroid cancer related mortality. It has, for the longest time, escaped all attempts to change its dismal prognosis – historically having a median survival of 4-6 months and very few, if any, long-term survivors. Progress in anaplastic thyroid cancer...

American Thyroid Association

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Acta Cirurgica Brasileira

Macro and microscopic comparison of the upper pole of the spleen with the lower pole in partial splenectomy

Abstract Purpose To evaluate the viability of the upper (UP) and lower pole (LP) of the spleen from a macro and microscopic point of view, after subtotal splenectomy with preservation (SSP) of the UP and the LP. Methods Seventeen male Wistar rats, two months old, were submitted to SSPUP and SSPLP and 5 to simulated operation (SG). After 80 days, the rats were euthanized, and the remaining LP and UP and intact spleens were evaluated macroscopically and microscopically. Results Two rats died...

Acta Cirurgica Brasileira

The examination of the nephroprotective effect of montelukast sodium and N-acetylcysteine ın renal ıschemia with dimercaptosuccinic acid imaging in a placebo-controlled rat model

Abstract Purpose To determine the nephroprotective effect of NAC and Montelukast Sodium administration against the development of renal damage associated with long warm renal ischemia. Methods Twenty-seven rats were randomly divided into 3 study groups, which received NAC, montelukast and placebo, and 3 rats were included in the sham-treated control group. Medications were given 3 days before the procedure. DMSA renal scintigraphy was performed before and after surgery. The right renal pedicle...

Acta Cirurgica Brasileira

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Allergy, Asthma & Clinical Immunology - Latest Articles

Multiple hepatic aneurysms and dry gangrene of fingertips in eosinophilic granulomatosis with polyangiitis: a case report

Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic necrotizing vasculitis mainly affecting small-sized arteries. Involvement of medium-sized vessels is very rare in EGPA. Here we present the ca...

Allergy, Asthma & Clinical Immunology - Latest Articles

Maternal vitamin D deficiency impairs Treg and Breg responses in offspring mice and deteriorates allergic airway inflammation

Vitamin D (VitD) can regulate immune responses and maternal VitD-deficiency can affect immune responses in the offspring. This study aimed at investigating the effects of maternal VitD-deficiency during pregna...

Allergy, Asthma & Clinical Immunology - Latest Articles

Aiming for a shorter time to diagnosis: pediatric eosinophilic esophagitis in British Columbia

Longer time to diagnosis for patients with eosinophilic esophagitis can lead to adverse patient outcomes, but the length of diagnostic delay has not been quantified for patients with eosinophilic esophagitis i...

Allergy, Asthma & Clinical Immunology - Latest Articles

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Acta Oto-Laryngologica Case Reports: Table of Contents: Taylor and Francis

Chondroid chordoma of the parapharyngeal space: A case report and review of literature

Volume 5, Issue 1, December 2020, Page 69-73.

Acta Oto-Laryngologica Case Reports: Table of Contents: Taylor and Francis

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One-Step surgical removal of a cutaneous melanoma: Current evidence

F. Russo - de la TorreActas Dermosifiliogr. 2020;111:541-4Full Text - PDF

Porokeratosis: A Review of its Pathophysiology, Clinical Manifestations, Diagnosis, and Treatment

P. Vargas-Mora, D. Morgado-Carrasco, X. Fustà-NovellActas Dermosifiliogr. 2020;111:545-60Abstract - Full Text - PDF

Doxycycline, an antibiotic or an anti-inflammatory agent? The Most Common uses in dermatology

FJ Navarro-Triviño, I Pérez-López, R Ruíz-VillaverdeActas Dermosifiliogr. 2020;111:561-6Abstract - Full Text - PDF

Quality Indicators in Care of Patients With Atopic Dermatitis: Consensus Document of the Spanish Academy of Dermatology and Venereology

I. Poveda-Montoyo, I. García-Doval, M.A. Descalzo, I. Betlloch-Mas, F.J. Miquel-Miquel, M. Serrano-Manzano, M.I. Martín-Delgado, T. Sanz-Sánchez, N. Knöpfel, S. Córdoba, A. Luca de Tena, A. Martín-Santiago, J.F. SilvestreActas Dermosifiliogr. 2020;111:567-73Abstract - Full Text - PDF

Efficacy of platelet rich plasma intradermal injections for androgenetic alopecia treatment in males: A Before and after study

S. Khaled Yaseer, F. Jamil Hassan, H. Badi SuleimanActas Dermosifiliogr. 2020;111:574-8Abstract - Full Text - PDF

Validation of a Questionnaire Designed to Study Knowledge, Attitudes, and Habits Related to Sun Exposure Among Young Adults: The CHACES Questionnaire

N. Blázquez-Sánchez, F. Rivas-Ruiz, S. Bueno-Fernández, S. Arias-Santiago, M.T. Fernández-Morano, M. deTroya-MartínActas Dermosifiliogr. 2020;111:579-89Abstract - Full Text - PDF

Reconstructing ear defects using the revolving door Island flap: A case series

M Franco-Muñoz, G Romero-Aguilera, M Flores-Terry, L González Ruíz, M Rogel Vence, MP Sánchez Caminero, M García-ArpaActas Dermosifiliogr. 2020;111:590-9Abstract - Full Text - PDF

Confluent, Retiform, Violaceous Hyperkeratotic Papules

E. Garzón AldásActas Dermosifiliogr. 2020;111:601-2Full Text - PDF

Pearly White Papules on the Antihelix

M. Oro-Ayude, R.M. Hernández Cancela, A. FlórezActas Dermosifiliogr. 2020;111:603-4Full Text - PDF

Photodynamic Therapy for Necrobiosis Lipoidica: Successful Treatment in a Series of 4 cases

E. Bernia, B. Llombart, B. Bancalari, A. Diago, C. Serra-GuillénActas Dermosifiliogr. 2020;111:605-8Abstract - Full Text - PDF

RF - Pharmacological Prevention of Nonmelanoma Skin Cancer in High-Risk Patients

X. Bosch-Amate, D. Morgado-Carrasco, N. MartínezActas Dermosifiliogr. 2020;111:609-10Full Text - PDF

«Before applying the next dose, peel the white film off the lesion»

A. López Gómez, Z. Ezsol Lendvai, M.I. de la Hera MatuteActas Dermosifiliogr. 2020;111:611Full Text - PDF

Peau d’Orange Appearance (Pseudocellulitis) and Elastography

F.C. Benavente Villegas, F. Alfageme Roldán, D. Suárez MassaActas Dermosifiliogr. 2020;111:612Full Text - PDF

Risk of Hepatitis B Virus Reactivation in Patients on Secukinumab for Psoriasis: A Series of 4 Cases

L.M. Moneva-Leniz, A. Sahuquillo-Torralba, A. Vila-Payeras, A. Mateu-PuchadesActas Dermosifiliogr. 2020;111:613-4Full Text - PDF

Stevens-Johnson Syndrome Secondary to Doxycycline Treatment in a Teenage Boy

D. Morgado-Carrasco, M.A. González Enseñat, C. Prat, A. Vicente-VillaActas Dermosifiliogr. 2020;111:615-7Full Text - PDF

Cryptococcal Immune Reconstitution Inflammatory Syndrome: An Unusual Presentation on the Tongue

J. Ballén, C. Quiroga, F. PalmaActas Dermosifiliogr. 2020;111:617-9Full Text - PDF

Melanoma in Noonan Syndrome With Multiple Lentigines (LEOPARD syndrome): A new case

M.F. García-Gil, M. Álvarez-Salafranca, A. Valero-Torres, M. Ara-MartínActas Dermosifiliogr. 2020;111:619-21Full Text - PDF

Pseudoflow in adnexal skin tumors

L. Turrión-Merino, F. Alfageme-Roldán, I. Salgüero-Fernández, C. Martínez-Mera, G. Roustan-GullonActas Dermosifiliogr. 2020;111:621-2Full Text - PDF

Prevalence of Syphilis in Children Adopted From Russia

G. Oliván-GonzalvoActas Dermosifiliogr. 2020;111:623-4Full Text - PDF

Lipschütz Ulcer: An Acute Noninfectious Genital Ulcer to Bear in Mind in Adult Women

D. Morgado-Carrasco, X. Bosch-Amate, X. Fustà-Novell, P. GiavedoniActas Dermosifiliogr. 2020;111:624-6Full Text - PDF

Chilblain and Acral Purpuric Lesions in COVID-19

V. WiwanitkitActas Dermosifiliogr. 2020;111:627Full Text - PDF

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

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Prähospitale Strategien zur Minimierung des Blutverlustes

Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55: 603-619DOI: 10.1055/a-0967-1586Die „kritische“ Blutung ist definiert durch ihr lebensbedrohliches Ausmaß und stellt die häufigste prähospital vermeidbare Todesursache dar. Für äußere Blutungen existieren adäquate prähospitale Therapiestrategien – sie müssen aber stets in ein Gesamtkonzept entsprechend dem <C>ABCDE-Algorithmus (<C> für „critical bleeding“) eingebettet sein. In diesem Beitrag wird auf lokale manuelle Maßnahmen zur...

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

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Alarmierung von Laien per App verbessert Reanimationserfolg

Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55: 582-583DOI: 10.1055/a-1258-0927Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals:Table of contents | Full text

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

Invasive notfallmedizinische Maßnahmen: eine ärztliche Kernkompetenz

Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55: 586-587DOI: 10.1055/a-1210-5720Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals:Table of contents | Full text

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

Rocuronium bei älteren Patienten: längere Anschlagszeit und längere Wirkdauer

Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55: 583-584DOI: 10.1055/a-1258-1721Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals:Table of contents | Full text

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

Leitlinien in der Praxis: der herzchirurgische Patient in der intensivmedizinischen Versorgung

Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55: 635-642DOI: 10.1055/a-1011-2078Die S3-Leitlinie zur intensivmedizinischen Versorgung herzchirurgischer Patienten – Hämodynamisches Monitoring und Herz-Kreislauf 1 vereint aktuelles Wissen zu Empfehlungen für das hämodynamische Monitoring und die differenzierte Kreislauftherapie bei herzchirurgischen Intensivpatienten. Zudem werden anzustrebende Zielparameter der Kreislauftherapie, Behandlungsstrategien bei Links- und Rechtsherzinsuffizienz...

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

Semiquantitative Kulturen von ESBL-Enterobacterales können VAP-Risiko vorhersagen

Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55: 584-584DOI: 10.1055/a-1258-1734Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals:Table of contents | Full text

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

Erweiterte Reanimationsmaßnahmen: die extrakorporale kardiopulmonale Reanimation

Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55: 588-602DOI: 10.1055/a-0967-1368Eine extrakorporale kardiopulmonale Reanimation (eCPR) gilt als Therapieoption bei therapierefraktärem Herz-Kreislauf-Versagen. Sie kann die Überlebensrate mit günstigem neurologischem Ergebnis bei hochselektierten Patienten deutlich verbessern. Dieser Beitrag schildert das Verfahren, die Kriterien bei der Entscheidung zur eCPR sowie die Vor- und Nachteile der beiden Optionen – In-Hospital- und Out-of-Hospital-Variante...

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

Thieme Teaching Award 2021

Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55: 585-585DOI: 10.1055/a-1234-4751Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals:Table of contents | Full text

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

Diagnostik und invasive Maßnahmen beim Thoraxtrauma

Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55: 620-633DOI: 10.1055/a-0967-1563Das Thoraxtrauma ist ein komplexes Verletzungsmuster, dessen Diagnostik und Therapie einem Notfallteam alles abverlangen. Der Begriff beschreibt Verletzungen des Brustkorbs in allen Facetten – von der Prellmarke eines Sicherheitsgurtes bis zum tödlichen Überrolltrauma mit Quetschung oder Zerreißung der Thoraxorgane. Bei der Therapie können sonografische Diagnostik und invasive Notfalltechniken erforderlich werden,...

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

Multiinfarktsyndrom nach Luftembolie bei Entfernung eines Zentralvenenkatheters

Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55: 644-647DOI: 10.1055/a-1142-1664Die Entfernung eines zentralvenösen Katheters auf einer Normalstation führt bei einem 53-jährigen Patienten mit einem bis dato nicht bekannten Ventrikelseptumdefekt zu einer paradoxen Luftembolie. Der Patient wird reanimationspflichtig und erleidet ein Multiinfarktsyndrom mit verheerenden neurologischen Ausfällen. Dieser Beitrag zeigt die Pathogenese und die erforderlichen Maßnahmen zur Vermeidung der paradoxen...

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

Maschinelle Beatmung: Konservative Sauerstofftherapie liefert keine Vorteile

Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55: 582-582DOI: 10.1055/a-1224-2847Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals:Table of contents | Full text

AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie

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Influence of Levobupivacaine Regional Scalp Block on Hemodynamic Stability, Intra- and Postoperative Opioid Consumption in Supratentorial Craniotomies: A Randomized Controlled Trial

BACKGROUND: The anesthetic management of supratentorial craniotomy (CR) necessitates tight intraoperative hemodynamic control. This type of surgery may also be associated with substantial postoperative pain. We aimed at evaluating the influence of regional scalp block (SB) on hemodynamic stability during the noxious events of supratentorial craniotomies and total intravenous anesthesia, its influence on intraoperative anesthetic agents’ consumption, and its effect on postoperative pain control....

Evaluation and Management of the Physiologically Difficult Airway: Consensus Recommendations From Society for Airway Management

Multiple international airway societies have created guidelines for the management of the difficult airway. In critically ill patients, there are physiologic derangements beyond inadequate airway protection or hypoxemia. These risk factors contribute to the “physiologically difficult airway” and are associated with complications including cardiac arrest and death. Importantly, they are largely absent from international guidelines. Thus, we created management recommendations for the physiologically...

Epidural Administration of Ropivacaine Reduces the Amplitude of Transcranial Electrical Motor–Evoked Potentials: A Double-Blinded, Randomized, Controlled Trial

BACKGROUND: An epidurally administered local anesthetic acts primarily on the epidural nerve roots and can act directly on the spinal cord through the dural sleeve. We hypothesized that epidurally administered ropivacaine would reduce the amplitude of transcranial electrical motor–evoked potentials by blocking nerve conduction in the spinal cord. Therefore, we conducted a double-blind, randomized, controlled trial. METHODS: Thirty adult patients who underwent lung surgery were randomly...

The Effect of Mechanical Ventilation With Low Tidal Volume on Blood Loss During Laparoscopic Liver Resection: A Randomized Controlled Trial

BACKGROUND: Control of bleeding during laparoscopic liver resection (LLR) is important for patient safety. It remains unknown what the effects of mechanical ventilation with varying tidal volumes on bleeding during LLR. Thus, this study aims to investigate whether mechanical ventilation with low tidal volume (LTV) reduces surgical bleeding during LLR. METHODS: In this prospective, randomized, and controlled clinical study, 82 patients who underwent scheduled LLR were enrolled and randomly...