Molecules, Vol. 25, Pages 4842: New Insights into The Photoactivity of Shape-Tailored BiVO4 Semiconductors via Photocatalytic Degradation Reactions and Classical Reduction Processes Molecules doi: 10.3390/molecules25204842 Authors: Zsolt Kása Enikő Eszter Almási Klára Hernádi Tamás Gyulavári Lucian Baia Gábor Veréb Zsuzsanna László Zsolt Pap In the present study, additive-free, pH-driven, hydrothermal crystallization was used to obtain shape-tailored monoclinic BiVO4...
Molecules, Vol. 25, Pages 4815: Ginsenoside Rb3 Inhibits Pro-Inflammatory Cytokines via MAPK/AKT/NF-κB Pathways and Attenuates Rat Alveolar Bone Resorption in Response to Porphyromonas gingivalis LPS Molecules doi: 10.3390/molecules25204815 Authors: Minmin Sun Yaoting Ji Zhen Li Rourong Chen Shuhui Zhou Chang Liu Minquan Du Conventional treatments for chronic periodontitis are less effective in controlling inflammation and often relapse. Therefore, it is necessary to...
Molecules, Vol. 25, Pages 4831: Targeting Metabolism in Cancer Cells and the Tumour Microenvironment for Cancer Therapy Molecules doi: 10.3390/molecules25204831 Authors: Jiaqi Li Jie Qing Eu Li Ren Kong Lingzhi Wang Yaw Chyn Lim Boon Cher Goh Andrea L. A. Wong Targeting altered tumour metabolism is an emerging therapeutic strategy for cancer treatment. The metabolic reprogramming that accompanies the development of malignancy creates targetable differences between cancer...
Molecules, Vol. 25, Pages 4822: Detection, Purification and Elucidation of Chemical Structure and Antiproliferative Activity of Taxol Produced by Penicillium chrysogenum Molecules doi: 10.3390/molecules25204822 Authors: Ashraf El-Sayed Gamal Enan Abdul-Raouf Al-Mohammadi Ahmed H. Moustafa Nashwa El-Gazzar Penicillium chrysogenum has been reported as a potent taxol producer based on quantitative analysis by TLC and HPLC. The biosynthetic potency of taxol has been validated...
Molecules, Vol. 25, Pages 4840: Transformations of Monoterpenes with the p-Menthane Skeleton in the Enzymatic System of Bacteria, Fungi and Insects Molecules doi: 10.3390/molecules25204840 Authors: Małgorzata Grabarczyk Wanda Mączka Anna K. Żołnierczyk Katarzyna Wińska The main objective of this article was to present the possibilities of using the enzymatic system of microorganisms and insects to transform small molecules, such as monoterpenes. The most important advantage...
Molecules, Vol. 25, Pages 4825: Synthesis, Crystallography, and Anti-Leukemic Activity of the Amino Adducts of Dehydroleucodine Molecules doi: 10.3390/molecules25204825 Authors: Paola E. Ordóñez David E. Mery Krishan K. Sharma Saumyadip Nemu William F. Reynolds Raul G. Enriquez Darcy C. Burns Omar Malagón Darin E. Jones Monica L. Guzman Cesar M. Compadre Dehydroleucodine is a bioactive sesquiterpene lactone. Herein, four dehydroleucodine amino derivatives...
Molecules, Vol. 25, Pages 4841: Pimpinella anisum Essential Oil Nanoemulsion Toxicity against Tribolium castaneum? Shedding Light on Its Interactions with Aspartate Aminotransferase and Alanine Aminotransferase by Molecular Docking Molecules doi: 10.3390/molecules25204841 Authors: Ahmed S. Hashem Marwa M. Ramadan Amira A. A. Abdel-Hady Stefania Sut Filippo Maggi Stefano Dall’Acqua The insecticidal activity is the result of a series of complex interactions between toxic...
Molecules, Vol. 25, Pages 4838: Lovastatin Differentially Regulates α7 and α4 Neuronal Nicotinic Acetylcholine Receptor Levels in Rat Hippocampal Neurons Molecules doi: 10.3390/molecules25204838 Authors: Virginia Borroni Constanza Kamerbeek María Pediconi Francisco Barrantes Neuronal α7 and α4β2 are the predominant nicotinic acetylcholine receptor (nAChR) subtypes found in the brain, particularly in the hippocampus. The effects of lovastatin, an inhibitor of cholesterol biosynthesis,...
Molecules, Vol. 25, Pages 4821: Chronological Review and Rational and Future Prospects of Cannabis-Based Drug Development Molecules doi: 10.3390/molecules25204821 Authors: Dvora Namdar Omer Anis Patrick Poulin Hinanit Koltai Despite the surge in cannabis chemistry research and its biological and medical activity, only a few cannabis-based pharmaceutical-grade drugs have been developed and marketed to date. Not many of these drugs are Food and Drug Administration (FDA)-approved,...
Molecules, Vol. 25, Pages 4837: The Effect of Partial Corticotomy on the Rate of Maxillary Canine Retraction: Clinical and Radiographic Study Molecules doi: 10.3390/molecules25204837 Authors: Hosam Ali Baeshen The study aimed to evaluate, clinically and radiographically, the effect of partial corticotomy of the buccal plate distal to the canine on the rate of maxillary canine retraction. A clinical trial with the split-mouth design was conducted among twenty orthodontic patients, recommended...
Molecules, Vol. 25, Pages 4836: Overexpression of GbF3′5′H1 Provides a Potential to Improve the Content of Epicatechin and Gallocatechin Molecules doi: 10.3390/molecules25204836 Authors: Yaqiong Wu Tongli Wang Yue Xin Guibin Wang Li-An Xu The flavonoids in Ginkgo biloba L. (ginkgo) have important medicinal uses due to their antioxidant, antitumor, and blood circulation-promoting effects. However, the genetic mechanisms underlying flavonoid biosynthesis in ginkgo remain elusive....
Molecules, Vol. 25, Pages 4835: Affinity of Antifungal Isoxazolo[3,4-b]pyridine-3(1H)-Ones to Phospholipids in Immobilized Artificial Membrane (IAM) Chromatography Molecules doi: 10.3390/molecules25204835 Authors: Krzesimir Ciura Joanna Fedorowicz Petar Žuvela Mario Lovrić Hanna Kapica Paweł Baranowski Wiesław Sawicki Ming Wah Wong Jarosław Sączewski Currently, rapid evaluation of the physicochemical parameters of drug candidates, such as lipophilicity, is in...
Molecules, Vol. 25, Pages 4839: The Multi-Faceted Effect of Curcumin in Glioblastoma from Rescuing Cell Clearance to Autophagy-Independent Effects Molecules doi: 10.3390/molecules25204839 Authors: Larisa Ryskalin Francesca Biagioni Carla L. Busceti Gloria Lazzeri Alessandro Frati Francesco Fornai The present review focuses on the multi-faceted effects of curcumin on the neurobiology glioblastoma multiforme (GBM), with a special emphasis on autophagy (ATG)-dependent molecular...
Molecules, Vol. 25, Pages 4834: Rab GTPase Mediating Regulation of NALP3 in Colorectal Cancer Molecules doi: 10.3390/molecules25204834 Authors: Gülçin Tezcan Ekaterina E. Garanina Margarita N. Zhuravleva Shaimaa Hamza Albert A. Rizvanov Svetlana F. Khaiboullina The NALP3 inflammasome signaling contributes to inflammation within tumor tissues. This inflammation may be promoted by the vesicle trafficking of inflammasome components and cytokines. Rab5, Rab7 and Rab11 regulate...
Molecules, Vol. 25, Pages 4833: Evaluation of Cytotoxicity and α-Glucosidase Inhibitory Activity of Amide and Polyamino-Derivatives of Lupane Triterpenoids Molecules doi: 10.3390/molecules25204833 Authors: Oxana B. Kazakova Gul’nara V. Giniyatullina Akhat G. Mustafin Denis A. Babkov Elena V. Sokolova Alexander A. Spasov A series of two new and twenty earlier synthesized branched extra-amino-triterpenoids obtained by the direct coupling of betulinic/betulonic acids with...
Molecules, Vol. 25, Pages 4832: Kinetic Study of Glucosamine Production Using Aspergillus sydowii BCRC 31742 under Solid-State Fermentation Molecules doi: 10.3390/molecules25204832 Authors: Jia Wei Peng Ho Shing Wu In the present study, we aimed to obtain a high yield and productivity for glucosamine using a low-cost solid-state culture with Aspergillus sydowii BCRC 31742. The fermentation conditions, such as inoculum biomass, moisture content, and supplemental volume and mineral...
Molecules, Vol. 25, Pages 4823: A Revised Structure and Assigned Absolute Configuration of Theissenolactone A Molecules doi: 10.3390/molecules25204823 Authors: Melissa M. Cadelis Soeren Geese Lauren Gris Bevan S. Weir Brent R. Copp Siouxsie Wiles Antimicrobial bioassay-guided fractionation of Microcera larvarum led to the isolation of a γ-lactone with a furo[3,4-b]pyran-5-one bicyclic ring system (1) and three known compounds, (3S,4R)-4-hydroxymellein (2), (3S,4S)-4-hydroxymellein...
Molecules, Vol. 25, Pages 4830: Screening of an Endophyte Transforming Polydatin to Resveratrol from Reynoutria Japonica Houtt and the Optimization of Its Transformation Parameters Molecules doi: 10.3390/molecules25204830 Authors: Jin Liu Xueqing Zhang Ting Yan Faling Wang Jing Li Lingyun Jia Jingming Jia Gaosheng Hu Resveratrol showed various kinds of bioactivities, such as antioxidant, antimicrobial, anticancer effects and, therefore, has been used widely as an...
Molecules, Vol. 25, Pages 4828: Synthesis of Benzimidazole–Based Analogs as Anti Alzheimer’s Disease Compounds and Their Molecular Docking Studies Molecules doi: 10.3390/molecules25204828 Authors: Bushra Adalat Fazal Rahim Muhammad Taha Foziah J. Alshamrani El Hassane Anouar Nizam Uddin Syed Adnan Ali Shah Zarshad Ali Zainul Amiruddin Zakaria We synthesized 10 analogs of benzimidazole-based thiosemicarbazide 1 (a–j) and 13 benzimidazole-based Schiff...
Molecules, Vol. 25, Pages 4829: Discovery of Potential Chemical Probe as Inhibitors of CXCL12 Using Ligand-Based Virtual Screening and Molecular Dynamic Simulation Molecules doi: 10.3390/molecules25204829 Authors: Sajjad Haider Assem Barakat Zaheer Ul-Haq CXCL12 are small pro-inflammatory chemo-attractant cytokines that bind to a specific receptor CXCR4 with a role in angiogenesis, tumor progression, metastasis, and cell survival. Globally, cancer metastasis is a major cause of...
Molecules, Vol. 25, Pages 4827: Smart Synthesis of Trimethyl Ethoxysilane (TMS) Functionalized Core–Shell Magnetic Nanosorbents Fe3O4@SiO2: Process Optimization and Application for Extraction of Pesticides Molecules doi: 10.3390/molecules25204827 Authors: Khalid Al-Saad Ahmed A. Issa Sourour Idoudi Basem Shomar Mohammad A. Al-Ghouti Nessreen Al-Hashimi Marwa El-Azazy In the current study, a smart approach for synthesizing trimethyl ethoxysilane–decorated magnetic-core...
Molecules, Vol. 25, Pages 4826: Roles of NAD+ and Its Metabolites Regulated Calcium Channels in Cancer Molecules doi: 10.3390/molecules25204826 Authors: Peilin Yu Xiaobo Cai Yan Liang Mingxiang Wang Wei Yang Nicotinamide adenine dinucleotide (NAD+) is an essential cofactor for redox enzymes, but also moonlights as a regulator for ion channels, the same as its metabolites. Ca2+ homeostasis is dysregulated in cancer cells and affects processes such as tumorigenesis, angiogenesis,...
Molecules, Vol. 25, Pages 4824: Electrical Properties Enhancement of Carbon Nanotube Yarns by Cyclic Loading Molecules doi: 10.3390/molecules25204824 Authors: Orli Weizman Joey Mead Hanna Dodiuk Samuel Kenig Carbon nanotube yarns (CNTYs) possess low density, high conductivity, high strength, and moderate flexibility. These intrinsic properties allow them to be a preferred choice for use as conductive elements in high-performance composites. To fully exploit their potential as...
Molecules, Vol. 25, Pages 4817: Seeding, Plating and Electrical Characterization of Gold Nanowires Formed on Self-Assembled DNA Nanotubes Molecules doi: 10.3390/molecules25204817 Authors: Dulashani R. Ranasinghe Basu R. Aryal Tyler R. Westover Sisi Jia Robert C. Davis John N. Harb Rebecca Schulman Adam T. Woolley Self-assembly nanofabrication is increasingly appealing in complex nanostructures, as it requires fewer materials and has potential to reduce feature sizes....
Molecules, Vol. 25, Pages 4819: How Do Aromatic Nitro Compounds React with Nucleophiles? Theoretical Description Using Aromaticity, Nucleophilicity and Electrophilicity Indices Molecules doi: 10.3390/molecules25204819 Authors: Kacper Błaziak Witold Danikiewicz Mieczysław Mąkosza In this study, we present a complete description of the addition of a model nucleophile to the nitroaromatic ring in positions occupied either by hydrogen (the first step of the SNAr-H reaction) or a leaving...
Molecules, Vol. 25, Pages 4818: Effect of Enzymatic, Ultrasound, and Reflux Extraction Pretreatments on the Chemical Composition of Essential Oils Molecules doi: 10.3390/molecules25204818 Authors: Anđela Miljanović Ana Bielen Dorotea Grbin Zvonimir Marijanović Martina Andlar Tonči Rezić Sunčica Roca Igor Jerković Dražen Vikić-Topić Maja Dent The effect of different hydrodistillation pretreatments, namely, reflux extraction, reflux extraction with the addition...
Molecules, Vol. 25, Pages 4820: Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics Molecules doi: 10.3390/molecules25204820 Authors: Anna O. Pinson Dakota L. Pouncey Mary A. Schleiff William E. Fantegrossi Paul L. Prather Anna Radominska-Pandya Gunnar Boysen Grover P. Miller In 2020, nearly one-third of new drugs on the global market were synthetic cannabinoids including the drug of abuse N-(1-adamantyl)-1-(5-pentyl)-1H-indazole-3-carboxamide...
Molecules, Vol. 25, Pages 4816: Supercritical Extraction of Red Propolis: Operational Conditions and Chemical Characterization Molecules doi: 10.3390/molecules25204816 Authors: João Henrique de Oliveira Reis Bruna Aparecida Souza Machado Gabriele de Abreu Barreto Jeancarlo Pereira dos Anjos Larissa Moraes dos Santos Fonseca Alex Alisson Bandeira Santos Fernando Luiz Pellegrini Pessoa Janice Izabel Druzian The objective of this study was to determine the best operational...
Molecules, Vol. 25, Pages 4814: Cytotoxic, Antitumor and Toxicological Profile of Passiflora alata Leaf Extract Molecules doi: 10.3390/molecules25204814 Authors: Ricardo G. Amaral Silvana V. F. Gomes Luciana N. Andrade Sara A. dos Santos Patrícia Severino Ricardo L. C. de Albuquerque Júnior Eliana B. Souto Geraldo C. Brandão Sandra L. Santos Jorge M. David Adriana A. Carvalho Passiflora alata or passion fruit is a native flowering plant from Amazon, geographically...
Molecules, Vol. 25, Pages 4813: Novel Nucleoside Analogues as Effective Antiviral Agents for Zika Virus Infections Molecules doi: 10.3390/molecules25204813 Authors: Marcella Bassetto Cecilia M. Cima Mattia Basso Martina Salerno Frank Schwarze Daniela Friese Joachim J. Bugert Andrea Brancale Previously considered a neglected flavivirus, Zika virus has recently emerged as a public health concern due to its ability to spread rapidly and cause severe neurological disorders,...
Molecules, Vol. 25, Pages 4812: Stacking Interactions of Poly Para-Phenylene Vinylene Oligomers with Graphene and Single-Walled Carbon Nanotubes: A Molecular Dynamics Approach Molecules doi: 10.3390/molecules25204812 Authors: Nii Amah Dagadu Shahram Ajori Yaw Delali Bensah Kwabena Kan-Dapaah Stephen Kofi Armah Boateng Onwona-Agyeman Abu Yaya This study is meant to address the understanding of the interactions between poly para-phenylene vinylene (PPV) oligomers, graphene...
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Nanomaterials, Vol. 10, Pages 2074: Microalgae-Templated Spray Drying for Hierarchical and Porous Fe3O4/C Composite Microspheres as Li-ion Battery Anode Materials Nanomaterials doi: 10.3390/nano10102074 Authors: Jinseok Park Jungmin Kim Dae Soo Jung Isheunesu Phiri Hyeon-Su Bae Jinseok Hong Sojin Kim Young-Gi Lee Myung-Hyun Ryou Kyubock Lee A method of microalgae-templated spray drying to develop hierarchical porous Fe3O4/C composite microspheres as anode materials...
Nanomaterials, Vol. 10, Pages 2073: From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials Nanomaterials doi: 10.3390/nano10102073 Authors: Valérie Fessard Fabrice Nesslany Genotoxicity is one of the key endpoints investigated as early as possible before marketing a product [...]
Nanomaterials, Vol. 10, Pages 2071: Icariin-Functionalized Nanodiamonds to Enhance Osteogenic Capacity In Vitro Nanomaterials doi: 10.3390/nano10102071 Authors: Somang Choi Sung Hyun Noh Chae Ouk Lim Hak-Jun Kim Han-Saem Jo Ji Seon Min Kyeongsoon Park Sung Eun Kim Nanodiamonds (NDs) have been used as drug delivery vehicles due to their low toxicity and biocompatibility. Recently, it has been reported that NDs have also osteogenic differentiation capacity. However,...
Nanomaterials, Vol. 10, Pages 2072: Magnetoelectric Composites: Applications, Coupling Mechanisms, and Future Directions Nanomaterials doi: 10.3390/nano10102072 Authors: Pradhan Kumari Rack Multiferroic (MF)-magnetoelectric (ME) composites, which integrate magnetic and ferroelectric materials, exhibit a higher operational temperature (above room temperature) and superior (several orders of magnitude) ME coupling when compared to single-phase multiferroic materials. Room temperature...
Nanomaterials, Vol. 10, Pages 2070: Topography: A Biophysical Approach to Direct the Fate of Mesenchymal Stem Cells in Tissue Engineering Applications Nanomaterials doi: 10.3390/nano10102070 Authors: Cun Hosta-Rigau Tissue engineering is a promising strategy to treat tissue and organ loss or damage caused by injury or disease. During the past two decades, mesenchymal stem cells (MSCs) have attracted a tremendous amount of interest in tissue engineering due to their multipotency...
Nanomaterials, Vol. 10, Pages 2069: Multi-Level Analog Resistive Switching Characteristics in Tri-Layer HfO2/Al2O3/HfO2 Based Memristor on ITO Electrode Nanomaterials doi: 10.3390/nano10102069 Authors: Chandreswar Mahata Myounggon Kang Sungjun Kim Atomic layer deposited (ALD) HfO2/Al2O3/HfO2 tri-layer resistive random access memory (RRAM) structure has been studied with a transparent indium tin oxide (ITO) transparent electrode. Highly stable and reliable multilevel conductance...
Nanomaterials, Vol. 10, Pages 2067: Trastuzumab Modified Barium Ferrite Magnetic Nanoparticles Labeled with Radium-223: A New Potential Radiobioconjugate for Alpha Radioimmunotherapy Nanomaterials doi: 10.3390/nano10102067 Authors: Weronika Gawęda Marek Pruszyński Edyta Cędrowska Magdalena Rodak Agnieszka Majkowska-Pilip Damian Gaweł Frank Bruchertseifer Alfred Morgenstern Aleksander Bilewicz Barium ferrite nanoparticles (BaFeNPs) were investigated as vehicles...
Nanomaterials, Vol. 10, Pages 2068: A Semi-Automated Workflow for FAIR Maturity Indicators in the Life Sciences Nanomaterials doi: 10.3390/nano10102068 Authors: Ammar Ammar Serena Bonaretti Laurent Winckers Joris Quik Martine Bakker Dieter Maier Iseult Lynch Jeaphianne van Rijn Egon Willighagen Data sharing and reuse are crucial to enhance scientific progress and maximize return of investments in science. Although attitudes are increasingly favorable, data reuse...
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Nutrients, Vol. 12, Pages 3207: Dietary Short-Term Fiber Interventions in Arthritis Patients Increase Systemic SCFA Levels and Regulate Inflammation Nutrients doi: 10.3390/nu12103207 Authors: Kerstin Dürholz Jörg Hofmann Aida Iljazovic Julian Häger Sébastien Lucas Kerstin Sarter Till Strowig Holger Bang Jürgen Rech Georg Schett Mario M. Zaiss Chronic inflammatory diseases are often initiated and guided by the release of proinflammatory mediators. Rheumatoid...
Nutrients, Vol. 12, Pages 3205: Effect of a Synbiotic Containing Lactobacillus paracasei and Opuntia humifusa on a Murine Model of Irritable Bowel Syndrome Nutrients doi: 10.3390/nu12103205 Authors: Seong Lee Min Jang Park Kim Lee Hong Chang The administration of a combination of probiotics and prebiotics is expected to be a promising strategy for improving irritable bowel syndrome (IBS) symptoms. This study aimed to investigate the efficacy of a synbiotic...
Nutrients, Vol. 12, Pages 3204: Fiber and Prebiotic Interventions in Pediatric Inflammatory Bowel Disease: What Role Does the Gut Microbiome Play? Nutrients doi: 10.3390/nu12103204 Authors: Healey Celiberto Lee Jacobson The etiology of inflammatory bowel disease (IBD) is complex but is thought to be linked to an intricate interaction between the host’s immune system, resident gut microbiome and environment, i.e., diet. One dietary component that has a major impact...
Nutrients, Vol. 12, Pages 3206: Effectiveness of Mediterranean Diet’s Adherence in children with Inflammatory Bowel Diseases Nutrients doi: 10.3390/nu12103206 Authors: Strisciuglio Cenni Serra Dolce Martinelli Staiano Miele Background: Nutritional support is very important in the treatment of Paediatric Inflammatory Bowel Disease (IBD). The role of the Mediterranean Diet (MD) has been understudied in children with IBD. The aims of this study were to assess the...
Nutrients, Vol. 12, Pages 3203: All-Cause Mortality and Cardiovascular Death between Statins and Omega-3 Supplementation: A Meta-Analysis and Network Meta-Analysis from 55 Randomized Controlled Trials Nutrients doi: 10.3390/nu12103203 Authors: Kim Hoang Kim Bu Choi Park Lee Park Min Lee Youn Yeon Statins and omega-3 supplementation have shown potential benefits in preventing cardiovascular disease (CVD), but their comparative effects on mortality...
Nutrients, Vol. 12, Pages 3202: Associations of Non-Alcoholic Beverages with Major Depressive Disorder History and Depressive Symptoms Clusters in a Sample of Overweight Adults Nutrients doi: 10.3390/nu12103202 Authors: Pérez-Ara Gili Visser Penninx Brouwer Watkins Owens García-Toro Hegerl Kohls Bot Roca Background: Meta-analysis of observational studies concluded that soft drinks may increase the risk of depression, while high consumption...
Nutrients, Vol. 12, Pages 3200: Inulin Supplementation Disturbs Hepatic Cholesterol and Bile Acid Metabolism Independent from Housing Temperature Nutrients doi: 10.3390/nu12103200 Authors: Mira J. Pauly Julia K. Rohde Clara John Ioannis Evangelakos Anja Christina Koop Paul Pertzborn Klaus Tödter Ludger Scheja Joerg Heeren Anna Worthmann Dietary fibers are fermented by gut bacteria into the major short chain fatty acids (SCFAs) acetate, propionate, and butyrate....
Nutrients, Vol. 12, Pages 3201: Breakfast Characteristics and Its Association with Daily Micronutrients Intake in Children and Adolescents–A Systematic Review and Meta-Analysis Nutrients doi: 10.3390/nu12103201 Authors: Giménez-Legarre Miguel-Berges Flores-Barrantes Santaliestra-Pasías Moreno Breakfast is an important source of key nutrients in the diet. For this reason, the aim of this review was to investigate the associations between breakfast consumption and daily...
Nutrients, Vol. 12, Pages 3198: The Role of Micronutrients in Support of the Immune Response against Viral Infections Nutrients doi: 10.3390/nu12103198 Authors: Francesco Pecora Federica Persico Alberto Argentiero Cosimo Neglia Susanna Esposito Viral infections are a leading cause of morbidity and mortality worldwide, and the importance of public health practices including handwashing and vaccinations in reducing their spread is well established. Furthermore, it is well known...
Nutrients, Vol. 12, Pages 3199: Efficacy of “High in” Nutrient Specific Front of Package Labels—A Retail Experiment with Canadians of Varying Health Literacy Levels Nutrients doi: 10.3390/nu12103199 Authors: Elizabeth D. Mansfield Dominique Ibanez Fuqi Chen Emily Chen Elaine de Grandpré Background: In 2018, Health Canada, the Federal department responsible for public health, put forward a regulatory proposal to introduce regulations requiring a “High in”...
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Particles, Vol. 3, Pages 676-692: Direct Photons from Hot Quark Matter in Renormalized Finite-Time-Path QED Particles doi: 10.3390/particles3040044 Authors: Ivan Dadić Dubravko Klabučar Domagoj Kuić Within the finite-time-path out-of-equilibrium quantum field theory (QFT), we calculate direct photon emission from early stages of heavy ion collisions, from a narrow window, in which uncertainty relations are still important and they provide a new mechanism for production of photons....
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Pathogens, Vol. 9, Pages 857: Molecular and Serological Prevalence of Leptospira spp. in Feral Pigs (Sus scrofa) and their Habitats in Alabama, USA Pathogens doi: 10.3390/pathogens9100857 Authors: Anil Poudel Md Monirul Hoque Steven Madere Sara Bolds Stuart Price Subarna Barua Folasade Adekanmbi Anwar Kalalah Steven Kitchens Vienna Brown Chengming Wang B. Graeme Lockaby Leptospirosis is a widespread zoonosis and has been recognized as a re-emerging infectious...
Pathogens, Vol. 9, Pages 856: Hepatitis E Virus Infection: Circulation, Molecular Epidemiology, and Impact on Global Health Pathogens doi: 10.3390/pathogens9100856 Authors: Srinivas Reddy Pallerla Dominik Harms Reimar Johne Daniel Todt Eike Steinmann Mathias Schemmerer Jürgen J. Wenzel Jörg Hofmann James Wai Kuo Shih Heiner Wedemeyer C.-Thomas Bock Thirumalaisamy P. Velavan Infection with hepatitis E virus (HEV) represents the most common source of viral...
Pathogens, Vol. 9, Pages 855: Ursolic Acid Potentializes Conventional Therapy in Experimental Leishmaniasis Pathogens doi: 10.3390/pathogens9100855 Authors: Jéssica Adriana Jesus Thays Nicolli Fragoso da Silva Eduardo Seiji Yamamoto João Henrique G. Lago Márcia Dalastra Laurenti Luiz Felipe Domingues Passero Ursolic acid (UA) is a triterpene with a broad array of pharmacological activities. In leishmaniasis, UA killed different species of parasites, and it was active in...
Pathogens, Vol. 9, Pages 854: Prevalence of Cytauxzoon felis Infection-Carriers in Eastern Kansas Domestic Cats Pathogens doi: 10.3390/pathogens9100854 Authors: Wikander Anantatat Kang Reif Cytauxzoon felis is a hemoprotozoal tick-transmitted pathogen of felids. Felids that survive acute disease often remain infected and serve as reservoirs for subsequent tick transmission to other susceptible felines. States adjacent to Kansas have identified C. felis-domestic cat carriers...
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Pharmaceuticals, Vol. 13, Pages 322: Anti-Stress Properties of Atypical Antipsychotics Pharmaceuticals doi: 10.3390/ph13100322 Authors: Sanson Riva Stress exposure represents a major environmental risk factor for schizophrenia and other psychiatric disorders, as it plays a pivotal role in the etiology as well as in the manifestation of disease symptomatology. It may be inferred that pharmacological treatments must be able to modulate the behavioral, functional, and molecular alterations...
Pharmaceuticals, Vol. 13, Pages 321: Antiarrhythmic Effect of Ranolazine in Combination with Selective NCX-Inhibition in an Experimental Model of Atrial Fibrillation Pharmaceuticals doi: 10.3390/ph13100321 Authors: Julian Wolfes Christian Ellermann Niklas Broer Benjamin Rath Kevin Willy Patrick Robert Leitz Philipp Sebastian Lange Lars Eckardt Gerrit Frommeyer The aim of this study was to investigate the effects of a combination of ranolazine with different selective...
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Pharmaceutics, Vol. 12, Pages 997: 1,1-Difluoroethane Detection Time in Blood after Inhalation Abuse Estimated by Monte Carlo PBPK Modeling Pharmaceutics doi: 10.3390/pharmaceutics12100997 Authors: Raul Huet Gunnar Johanson (1) Background: Inhalant abuse and misuse are still widespread problems. 1,1-Difluoroethane abuse is reported to be potentially fatal and to cause acute and chronic adverse health effects. Lab testing for difluoroethane is seldom done, partly because the maximum...
Pharmaceutics, Vol. 12, Pages 992: Engineered Human Nanoferritin Bearing the Drug Genz-644282 for Cancer Therapy Pharmaceutics doi: 10.3390/pharmaceutics12100992 Authors: Elisabetta Falvo Alessandro Arcovito Giamaica Conti Giuseppe Cipolla Martina Pitea Veronica Morea Verena Damiani Gianluca Sala Giulio Fracasso Pierpaolo Ceci Gastrointestinal tumors, including pancreatic and colorectal cancers, represent one of the greatest public health issues worldwide,...
Pharmaceutics, Vol. 12, Pages 995: Combining Surface Templating and Confinement for Controlling Pharmaceutical Crystallization Pharmaceutics doi: 10.3390/pharmaceutics12100995 Authors: Manali Banerjee Blair Brettmann Poor water solubility is one of the major challenges to the development of oral dosage forms containing active pharmaceutical ingredients (APIs). Polymorphism in APIs leads to crystals with different surface wettabilities and free energies, which can lead to different...
Pharmaceutics, Vol. 12, Pages 994: In Vitro Performance of Dutasteride-Nanostructured Lipid Carriers Coated with Lauric Acid-Chitosan Oligomer for Dermal Delivery Pharmaceutics doi: 10.3390/pharmaceutics12100994 Authors: Norhayati Mohamed Noor Azila Abdul-Aziz Khalid Sheikh Satyanarayana Somavarapu Kevin M. G. Taylor Dutasteride, licensed as an oral medicine for the treatment of benign prostatic hypoplasia, has been investigated as a treatment for androgenic alopecia. In...
Pharmaceutics, Vol. 12, Pages 993: Increased Carrier Peptide Stability through pH Adjustment Improves Insulin and PTH(1-34) Delivery In Vitro and In Vivo Rather than by Enforced Carrier Peptide-Cargo Complexation Pharmaceutics doi: 10.3390/pharmaceutics12100993 Authors: Mie Kristensen Ragna Guldsmed Diedrichsen Valeria Vetri Vito Foderà Hanne Mørck Nielsen Oral delivery of therapeutic peptides is hampered by their large molecular size and labile nature, thus limiting their...
Pharmaceutics, Vol. 12, Pages 996: Targeting EphA2 in Bladder Cancer Using a Novel Antibody-Directed Nanotherapeutic Pharmaceutics doi: 10.3390/pharmaceutics12100996 Authors: Walid Kamoun Elden Swindell Christine Pien Lia Luus Jason Cain Minh Pham Irawati Kandela Zhaohua Richard Huang Suresh K. Tipparaju Alexander Koshkaryev Vasileios Askoxylakis Dmitri B. Kirpotin Troy Bloom Mari Mino-Kenudson James D. Marks Alena Zalutskaya Wiam Bshara Carl...
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Plants, Vol. 9, Pages 1397: Antioxidant Responses of Phenolic Compounds and Immobilization of Copper in Imperata Cylindrica, a Plant with Potential Use for Bioremediation of Cu Contaminated Environments Plants doi: 10.3390/plants9101397 Authors: Catalina Vidal Antonieta Ruiz Javier Ortiz Giovanni Larama Rodrigo Perez Christian Santander Paulo Ademar Avelar Ferreira Pablo Cornejo This work examined the capability of Imperata cylindrica to respond, tolerate and accumulate...
Plants, Vol. 9, Pages 1396: Agro-Morphological, Microanatomical and Molecular Cytogenetic Characterization of the Medicinal Plant Chelidonium majus L Plants doi: 10.3390/plants9101396 Authors: Tatiana E. Samatadze Olga Yu. Yurkevich Firdaus M. Hazieva Elena A. Konyaeva Alexander I. Morozov Svyatoslav A. Zoshchuk Alexandra V. Amosova Olga V. Muravenko Chelidonium majus L. is a medicinal plant well-known as a valuable source of isoquinoline alkaloids, which has a variety...
Plants, Vol. 9, Pages 1394: Polyphenols Content in Capsicum chinense Fruits at Different Harvest Times and Their Correlation with the Antioxidant Activity Plants doi: 10.3390/plants9101394 Authors: Julio Enrique Oney-Montalvo Kevin Alejandro Avilés-Betanzos Emmanuel de Jesús Ramírez-Rivera Manuel Octavio Ramírez-Sucre Ingrid Mayanin Rodríguez-Buenfil The aim of this work was to investigate the changes of the content of polyphenols in fruits of Capsicum chinense Jacq. at different...
Plants, Vol. 9, Pages 1393: In Silico Analyses of Autophagy-Related Genes in Rapeseed (Brassica napus L.) under Different Abiotic Stresses and in Various Tissues Plants doi: 10.3390/plants9101393 Authors: Eshkiki Hajiahmadi Abedi Kordrostami Jacquard The autophagy-related genes (ATGs) play important roles in plant growth and response to environmental stresses. Brassica napus (B. napus) is among the most important oilseed crops, but ATGs are largely unknown in this species....
Plants, Vol. 9, Pages 1392: Phenotypic Variability and Genetic Diversity of Phragmites australis in Quebec and Kashmir Reveal Contrasting Population Structure Plants doi: 10.3390/plants9101392 Authors: Wani Shah Tekeu Reshi Atangana Khasa The origin of differences in traits influencing competitive success between invasive and native wild populations of alien species is subject of debate. Herbarium-based information sources from 2005 onwards about nativity and distributional...
Plants, Vol. 9, Pages 1395: Investigating Plant Micro-Remains Embedded in Dental Calculus of the Phoenician Inhabitants of Motya (Sicily, Italy) Plants doi: 10.3390/plants9101395 Authors: Alessia D’Agostino Antonella Canini Gabriele Di Marco Lorenzo Nigro Federica Spagnoli Angelo Gismondi Plant records reveal remarkable evidence about past environments and human cultures. Exploiting dental calculus analysis and using a combined approach of microscopy and gas chromatography...
Plants, Vol. 9, Pages 1391: Seed Rain, Soil Seed Bank, and Seedling Emergence Indicate Limited Potential for Self-Recovery in a Highly Disturbed, Tropical, Mixed Deciduous Forest Plants doi: 10.3390/plants9101391 Authors: Anussara Chalermsri La-aw Ampornpan Witoon Purahong Human activity negatively affects the sustainability of forest ecosystems globally. Disturbed forests may or may not recover by themselves in a certain period of time. However, it is still unclear as to what...
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Religions, Vol. 11, Pages 539: Narratives in Action: Modelling the Types and Drivers of Sikh Activism in Diaspora Religions doi: 10.3390/rel11100539 Authors: Jasjit Singh Using data gathered for an investigation of “Sikh radicalisation in Britain”, in this article I develop a typology of different types of activism among Sikhs in diaspora based on an analysis of historic and contemporary media sources (newspapers, radio, television, online), academic literature, ethnographic...
Religions, Vol. 11, Pages 537: Facing the New Situation of Religious Education in Iceland Religions doi: 10.3390/rel11100537 Authors: Gunnar J. Gunnarsson Over the last two decades, Iceland has faced rapid societal changes in many ways, and cultural and religious diversity has grown faster than ever before. This has influenced the curricula of religious education. In 2011/2013, drastic changes were made to the National Curriculum Guide, and the curricula of individual subjects were merged...
Religions, Vol. 11, Pages 538: Be Gentle to Them: Animal Welfare and the Protection of Draft Animals in the Ottoman Fatwā Literature and Legislation Religions doi: 10.3390/rel11100538 Authors: Necmettin Kızılkaya Animal studies in the Islamic context have greatly increased in number in recent years. These studies mostly examine the subject of animal treatment through the two main sources of Islam, namely, the Qur’an and the traditions of the Prophet Muhammad. Some studies that...
Religions, Vol. 11, Pages 536: Spiritual Diversity, Spiritual Assessment, and Māori End-of-Life Perspectives: Attaining Ka Ea Religions doi: 10.3390/rel11100536 Authors: Holly Nelson-Becker Tess Moeke-Maxwell The contemporary world is endowed with increasingly diverse spiritual and cultural perspectives, yet little is known about the spiritual concerns and spiritual resilience of Māori from Aotearoa New Zealand at the end of life. A context is provided for the value of spiritual assessment...
Religions, Vol. 11, Pages 535: Erratum: Blankinship, Kevin. 2020. Suffering the Sons of Eve: Animal Ethics in al-Maʿarrī’s Epistle of the Horse and the Mule. Religions 11: 412 Religions doi: 10.3390/rel11100535 Authors: Kevin Blankinship The author would like to make the following changes to the published paper (Blankinship 2020): Citation “Blankinship 2019a, pp [...]
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Resources, Vol. 9, Pages 124: Assessing the Impact of Water Salinization Stress on Biomass Yield of Cardoon Bio-Energetic Crops through Remote Sensing Techniques Resources doi: 10.3390/resources9100124 Authors: Flavio Borfecchia Paola Crinò Angelo Correnti Anna Farneti Luigi De Cecco Domenica Masci Luciano Blasi Domenico Iantosca Vito Pignatelli Carla Micheli Various species of cultivated thistle, such as Cynara cardunculus L. (cardoon), exhibit interesting...
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Risks, Vol. 8, Pages 110: Determining Economic Security of a Business Based on Valuation of Intangible Assets according to the International Valuation Standards (IVS) Risks doi: 10.3390/risks8040110 Authors: Dmitrii Rodionov Olesya Perepechko Olga Nadezhina This work considered the economic security of an enterprise with regard to the valuation of intangible assets according to the International Valuation Standards (IVS). This study is essential due to a growing number of companies...
Risks, Vol. 8, Pages 109: The Linear Link: Deriving Age-Specific Death Rates from Life Expectancy Risks doi: 10.3390/risks8040109 Authors: Marius D. Pascariu Ugofilippo Basellini José Manuel Aburto Vladimir Canudas-Romo The prediction of human longevity levels in the future by direct forecasting of life expectancy offers numerous advantages, compared to methods based on extrapolation of age-specific death rates. However, the reconstruction of accurate life tables starting from...
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Safety, Vol. 6, Pages 48: Emergency Response to Vehicle Collisions: Feedback from Emergency Medical Service Providers Safety doi: 10.3390/safety6040048 Authors: Jacob T. Valente Miguel A. Perez (1) Background: The purpose of this study is to identify emergency medical technicians’ perceptions of the most pressing issues that they experience when responding to motor vehicle collisions and record their opinions about what information is needed to improve the efficiency and...
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Sci, Vol. 2, Pages 77: Atmospheric Temperature and CO2: Hen-or-Egg Causality? (Version 2) Sci doi: 10.3390/sci2040077 Authors: Demetris Koutsoyiannis Zbigniew W. Kundzewicz It is common knowledge that increasing CO2 concentration plays a major role in enhancement of the greenhouse effect and contributes to global warming. The purpose of this study is to complement the conventional and established theory that increased CO2 concentration due to human emissions causes an increase of...
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Sci. Pharm., Vol. 88, Pages 49: Anti-Proliferative and Genotoxic Activities of the Helichrysum petiolare Hilliard & B.L. Burtt Scientia Pharmaceutica doi: 10.3390/scipharm88040049 Authors: Idowu Jonas Sagbo Wilfred Otang-Mbeng Helichrysum petiolare (Asteraceae family) is part of the Helichrysum genus which comprises of an estimated 600 species. Several parts of the plant have been used traditionally for the treatment of various ailments, such as cough, infection, asthma, chest...
Sci. Pharm., Vol. 88, Pages 48: Prevalence of Drug Interaction in Severely Obese Individuals and Associated Factors: Baseline Results from a Clinical Trial Scientia Pharmaceutica doi: 10.3390/scipharm88040048 Authors: Ana Carolina Figueiredo Modesto Erika Aparecida Silveira Ana Paula dos Santos Rodrigues Dione Marçal Lima Mércia Pandolfo Provin Rita Goreti Amaral The prevalence of obesity is increasing worldwide and is commonly associated with comorbidities. The use of...
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Technologies, Vol. 8, Pages 56: Nonlinear Dynamic Behavior of Porous and Imperfect Bernoulli-Euler Functionally Graded Nanobeams Resting on Winkler Elastic Foundation Technologies doi: 10.3390/technologies8040056 Authors: Rosa Penna Luciano Feo Nonlinear free vibrations of functionally graded porous Bernoulli–Euler nano-beams resting on an elastic foundation through a stress-driven nonlocal elasticity model are studied taking into account von Kármán...
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Toxics, Vol. 8, Pages 90: Associations between Maternal Cadmium Exposure with Risk of Preterm Birth and Low Birth Weight Effect of Mediterranean Diet Adherence on Affected Prenatal Outcomes Toxics doi: 10.3390/toxics8040090 Authors: Sarah Gonzalez-Nahm Kiran Nihlani John S. House Rachel L. Maguire Harlyn G. Skinner Cathrine Hoyo Prenatal cadmium exposure at non-occupational levels has been associated with poor birth outcomes. The intake of essential metals, such as iron...
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Toxins, Vol. 12, Pages 665: Transcriptomic Insights into the Antifungal Effects of Magnolol on the Growth and Mycotoxin Production of Alternaria alternata Toxins doi: 10.3390/toxins12100665 Authors: Liuqing Wang Duo Wang Shuzhi Yuan Xiaoyuan Feng Meng Wang Alternaria alternata is an important phytopathogen causing fruit black rot and also producing a variety of mycotoxins, such as alternariol (AOH) and alternariol monomethyl ether (AME) as two main contaminants. This could...
Toxins, Vol. 12, Pages 664: Toxin Degradation by Rumen Microorganisms: A Review Toxins doi: 10.3390/toxins12100664 Authors: Zhi Hung Loh Diane Ouwerkerk Athol V. Klieve Natasha L. Hungerford Mary T. Fletcher Animal feeds may contain exogenous compounds that can induce toxicity when ruminants ingest them. These toxins are secondary metabolites originating from various sources including plants, bacteria, algae and fungi. Animal feed toxins are responsible for various animal...
Toxins, Vol. 12, Pages 663: The Presence of Mycotoxins in Feed and Their Influence on Animal Health Toxins doi: 10.3390/toxins12100663 Authors: Maciej T. Gajęcki Magdalena Gajęcka Łukasz Zielonka Mycotoxins are secondary metabolites of fungi [...]
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TropicalMed, Vol. 5, Pages 161: Vector-Focused Approaches to Curb Malaria Transmission in the Brazilian Amazon: An Overview of Current and Future Challenges and Strategies Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5040161 Authors: Elerson Matos Rocha Ricardo de Melo Katak Juan Campos de Oliveira Maisa da Silva Araujo Bianca Cechetto Carlos Roberto Galizi Frederic Tripet Osvaldo Marinotti Jayme A. Souza-Neto In Brazil, malaria transmission...
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Vaccines, Vol. 8, Pages 619: A DNA Vaccine Encoding Plasmodium falciparum PfRH5 in Cationic Liposomes for Dermal Tattooing Immunization Vaccines doi: 10.3390/vaccines8040619 Authors: Wesley Luzetti Fotoran Nicole Kleiber Christiane Glitz Gerhard Wunderlich Vaccines are the primary means of controlling and preventing pandemics and outbreaks of pathogens such as bacteria, viruses, and parasites. However, a major drawback of naked DNA-based vaccines is their low immunogenicity...
Vaccines, Vol. 8, Pages 618: Immunogenicity of Alternative Dosing Schedules for HPV Vaccines among Adolescent Girls and Young Women: A Systematic Review and Meta-Analysis Vaccines doi: 10.3390/vaccines8040618 Authors: Andrew M. Secor Matthew Driver Brenda Kharono Dianna Hergott Gui Liu Ruanne V. Barnabas Peter Dull Stephen E. Hawes Paul K. Drain Alternative dosing schedules for licensed human papilloma virus (HPV) vaccines, particularly single dose and extended...
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Veterinary Sciences, Vol. 7, Pages 158: Correction: Ali, A., et al. Modeling Novel Putative Drugs and Vaccine Candidates against Tick-Borne Pathogens: A Subtractive Proteomics Approach. Vet. Sci. 2020, 7, 129 Veterinary Sciences doi: 10.3390/vetsci7040158 Authors: Abid Ali Shabir Ahmad Abdul Wadood Ashfaq U. Rehman Hafsa Zahid Muhammad Qayash Khan Javed Nawab Zia Ur Rahman Abdulaziz S. Alouffi The authors wish to make the following corrections to this paper [...]
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Vibration, Vol. 3, Pages 357-370: Frequency Masking Effects for Vertical Whole-Body Vibration for Seated Subjects Vibration doi: 10.3390/vibration3040024 Authors: Anna Schwendicke M. Ercan Altinsoy Masking occurs when the perception of a stimulus is affected or covered by the presence of another signal in close proximity either in time or frequency. This study investigated frequency masking effects across a wide frequency range for whole-body vibration (WBV). The hypothesis that masking...
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Viruses, Vol. 12, Pages 1191: Poxviral Targeting of Interferon Regulatory Factor Activation Viruses doi: 10.3390/v12101191 Authors: Clara Lawler Gareth Brady As viruses have a capacity to rapidly evolve and continually alter the coding of their protein repertoires, host cells have evolved pathways to sense viruses through the one invariable feature common to all these pathogens—their nucleic acids. These genomic and transcriptional pathogen-associated molecular patterns...
Viruses, Vol. 12, Pages 1195: Development of a New Tomato Torrado Virus-Based Vector Tagged with GFP for Monitoring Virus Movement in Plants Viruses doi: 10.3390/v12101195 Authors: Przemysław Wieczorek Marta Budziszewska Patryk Frąckowiak Aleksandra Obrępalska-Stęplowska Green fluorescent protein (GFP)-tagged viruses are basic research tools widely applied in studies concerning molecular determinants of disease during virus infection. Here, we described a new generation of genetically...
Viruses, Vol. 12, Pages 1192: A Comprehensive Proteomics Analysis of the JC Virus (JCV) Large and Small Tumor Antigen Interacting Proteins: Large T Primarily Targets the Host Protein Complexes with V-ATPase and Ubiquitin Ligase Activities While Small t Mostly Associates with Those Having Phosphatase and Chromatin-Remodeling Functions Viruses doi: 10.3390/v12101192 Authors: Sami Saribas Mahmut Safak The oncogenic potential of both the polyomavirus large (LT-Ag) and small (Sm t-Ag)...
Viruses, Vol. 12, Pages 1193: Evaluation in Swine of a Recombinant African Swine Fever Virus Lacking the MGF-360-1L Gene Viruses doi: 10.3390/v12101193 Authors: Elizabeth Ramirez-Medina Elizabeth A. Vuono Ayushi Rai Sarah Pruitt Ediane Silva Lauro Velazquez-Salinas James Zhu Douglas P. Gladue Manuel V. Borca The African swine fever (ASF) pandemic is currently affecting pigs throughout Eurasia, resulting in significant swine production losses. The causative agent,...
Viruses, Vol. 12, Pages 1190: Phosphoinositide 3′-Kinase γ Facilitates Polyomavirus Infection Viruses doi: 10.3390/v12101190 Authors: Paul Clark Gretchen V. Gee Brandon S. Albright Benedetta Assetta Ying Han Walter J. Atwood Daniel DiMaio Polyomaviruses are small, non-enveloped DNA tumor viruses that cause serious disease in immunosuppressed people, including progressive multifocal leukoencephalopathy (PML) in patients infected with JC polyomavirus, but the molecular...
Viruses, Vol. 12, Pages 1194: Adeno-Associated Virus (AAV-DJ)—Cryo-EM Structure at 1.56 Å Resolution
Viruses, Vol. 12, Pages 1194: Adeno-Associated Virus (AAV-DJ)—Cryo-EM Structure at 1.56 Å Resolution Viruses doi: 10.3390/v12101194 Authors: Xie Yoshioka Chapman Adeno-associated virus is the leading viral vector for gene therapy. AAV-DJ is a recombinant variant developed for tropism to the liver. The AAV-DJ structure has been determined to 1.56 Å resolution through cryo-electron microscopy (cryo-EM). Only apoferritin is reported in preprints at 1.6 Å or...
Viruses, Vol. 12, Pages 1186: A Decade in Review: A Systematic Review of Universal Influenza Vaccines in Clinical Trials during the 2010 Decade Viruses doi: 10.3390/v12101186 Authors: Brigette N. Corder Brianna L. Bullard Gregory A. Poland Eric A. Weaver On average, there are 3–5 million severe cases of influenza virus infections globally each year. Seasonal influenza vaccines provide limited protection against divergent influenza strains. Therefore, the development...
Viruses, Vol. 12, Pages 1188: Budding of a Retrovirus: Some Assemblies Required Viruses doi: 10.3390/v12101188 Authors: Kevin M. Rose Vanessa M. Hirsch Fadila Bouamr One of the most important steps in any viral lifecycle is the production of progeny virions. For retroviruses as well as other viruses, this step is a highly organized process that occurs with exquisite spatial and temporal specificity on the cellular plasma membrane. To facilitate this process, retroviruses encode...
Viruses, Vol. 12, Pages 1187: A Systematic Evaluation of High-Throughput Sequencing Approaches to Identify Low-Frequency Single Nucleotide Variants in Viral Populations Viruses doi: 10.3390/v12101187 Authors: David J. King Graham Freimanis Lidia Lasecka-Dykes Amin Asfor Paolo Ribeca Ryan Waters Donald P. King Emma Laing High-throughput sequencing such as those provided by Illumina are an efficient way to understand sequence variation within viral populations. However,...
Viruses, Vol. 12, Pages 1184: Frequency and Duration of SARS-CoV-2 Shedding in Oral Fluid Samples Assessed by a Modified Commercial Rapid Molecular Assay Viruses doi: 10.3390/v12101184 Authors: Licia Bordi Giuseppe Sberna Eleonora Lalle Francesca Colavita Emanuele Nicastri Pierluca Piselli Andrea Antinori Evangelo Boumis Nicola Petrosillo Luisa Marchioni Giulia Minnucci Elena D’Agostini Concetta Castilletti Giuseppe Ippolito Franco Locatelli Alimuddin...
Viruses, Vol. 12, Pages 1185: Deletion of CD2-Like (CD2v) and C-Type Lectin-Like (EP153R) Genes from African Swine Fever Virus Georgia-∆9GL Abrogates Its Effectiveness as an Experimental Vaccine Viruses doi: 10.3390/v12101185 Authors: Douglas P. Gladue Vivian O’Donnell Elizabeth Ramirez-Medina Ayushi Rai Sarah Pruitt Elizabeth A. Vuono Ediane Silva Lauro Velazquez-Salinas Manuel V. Borca African swine fever virus (ASFV) is currently the most dreaded infectious...
Viruses, Vol. 12, Pages 1189: Are Viral Vectors Any Good for RNAi Antiviral Therapy? Viruses doi: 10.3390/v12101189 Authors: Kenneth Lundstrom RNA interference (RNAi) represents a novel approach for alternative antiviral therapy. However, issues related to RNA delivery and stability have presented serious obstacles for obtaining good therapeutic efficacy. Viral vectors are capable of efficient delivery of RNAi as short interfering RNA (siRNA), short hairpin RNA (shRNA) and micro-RNA...
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Water, Vol. 12, Pages 2933: Biochar from Agricultural By-Products for the Removal of Lead and Cadmium from Drinking Water Water doi: 10.3390/w12102933 Authors: Edgar Pineda Puglla Diana Guaya Cristhian Tituana Francisco Osorio María J. García-Ruiz This study reports the adsorption capacity of lead Pb2+ and cadmium Cd2+ of biochar obtained from: peanut shell (BCM), “chonta” pulp (BCH) and corn cob (BZM) calcined at 500, 600 and 700 °C, respectively....
Water, Vol. 12, Pages 2932: Redox Dependent Arsenic Occurrence and Partitioning in an Industrial Coastal Aquifer: Evidence from High Spatial Resolution Characterization of Groundwater and Sediments Water doi: 10.3390/w12102932 Authors: Chiara Sbarbati Maurizio Barbieri Alyssa Barron Benjamin Bostick Nicolò Colombani Micòl Mastrocicco Henning Prommer Stefania Passaretti Yan Zheng Marco Petitta Superlative levels of arsenic (As) in groundwater and sediment often...
Water, Vol. 12, Pages 2930: Simulation of Water-Use Efficiency of Crops under Different Irrigation Strategies Water doi: 10.3390/w12102930 Authors: Mathias Kuschel-Otárola Diego Rivera Eduardo Holzapfel Niels Schütze Patricio Neumann Alex Godoy-Faúndez Irrigation management is a key factor in attaining optimal yields, as different irrigation strategies lead to different yields even when using the same amount of water or under the same weather conditions. Our research aimed...
Water, Vol. 12, Pages 2931: Evaluation of Ground Temperature Changes by the Operation of the Geothermal Heat Pump System and Climate Change in Korea Water doi: 10.3390/w12102931 Authors: Seong-Kyun Kim Youngmin Lee To evaluate long-term temperature changes caused by the operation of a geothermal heat pump (GHP) system, temperatures near borehole heat exchangers (BHEs) of the GHP system in Korea were measured. The temperature measurements showed increasing rates of 0.135 °C/year...
Water, Vol. 12, Pages 2929: A Theoretical Study about Ergodicity Issues in Predicting Contaminant Plume Evolution in Aquifers Water doi: 10.3390/w12102929 Authors: Marilena Pannone A large-time Eulerian–Lagrangian stochastic approach is employed to: (1) estimate centroid position uncertainty of contaminant plumes that originate from instantaneous point sources in statistically stationary and isotropic porous formations; (2) assess the time needed for achieving ergodic conditions,...
Water, Vol. 12, Pages 2927: Development and Evaluation of the Combined Machine Learning Models for the Prediction of Dam Inflow Water doi: 10.3390/w12102927 Authors: Jiyeong Hong Seoro Lee Joo Hyun Bae Jimin Lee Woon Ji Park Dongjun Lee Jonggun Kim Kyoung Jae Lim Predicting dam inflow is necessary for effective water management. This study created machine learning algorithms to predict the amount of inflow into the Soyang River Dam in South Korea, using weather and...
Water, Vol. 12, Pages 2928: An Interactive Data Visualization Framework for Exploring Geospatial Environmental Datasets and Model Predictions Water doi: 10.3390/w12102928 Authors: Jeffrey D. Walker Benjamin H. Letcher Kirk D. Rodgers Clint C. Muhlfeld Vincent S. D’Angelo With the rise of large-scale environmental models comes new challenges for how we best utilize this information in research, management and decision making. Interactive data visualizations can make large...
Water, Vol. 12, Pages 2926: Environmental Benefits and Economical Sustainability of Urban Wastewater Reuse for Irrigation—A Cost-Benefit Analysis of an Existing Reuse Project in Puglia, Italy Water doi: 10.3390/w12102926 Authors: Claudio Arena Mario Genco Mario Rosario Mazzola Besides benefits associated to increased water availability for irrigation, reuse projects of urban water can also provide positive environmental impacts, as they contribute to improve water quality of the...
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