JCM, Vol. 9, Pages 3332: The Eye as a Non-Invasive Window to the Microcirculation in Liver Cirrhosis: A Prospective Pilot Study Journal of Clinical Medicine doi: 10.3390/jcm9103332 Authors: Fiona J Gifford Francesca Moroni Tariq E Farrah Kirstie Hetherington Tom J MacGillivray Peter C Hayes Neeraj Dhaun Jonathan A Fallowfield Microcirculatory dysfunction is associated with organ failure, poor response to vasoactive drugs and increased mortality in cirrhosis, but...
Sat Oct 17, 2020 03:00
JCM, Vol. 9, Pages 3331: Localization of Integrin Beta-4 Subunit at Soft Tissue–Titanium or Zirconia Interface Journal of Clinical Medicine doi: 10.3390/jcm9103331 Authors: Yasunori Ayukawa Ikiru Atsuta Yasuko Moriyama Yohei Jinno Kiyoshi Koyano Currently, along with titanium (Ti), zirconia is widely used as an abutment material for dental implants because it makes it possible to avoid gingival discoloration; however, the epithelial sealing capability of zirconia remains...
Sat Oct 17, 2020 03:00
JCM, Vol. 9, Pages 3329: Retinal Vascular Features in Ocular Blunt Trauma by Optical Coherence Tomography Angiography Journal of Clinical Medicine doi: 10.3390/jcm9103329 Authors: Daniela Montorio Luca D’Andrea Gilda Cennamo In this prospective study, we analysed the changes in retinal vessel density (VD) using optical coherence tomography angiography (OCTA) in patients with commotio retinae up to 6 months after blunt ocular trauma. We analysed the VD in the superficial capillary...
Fri Oct 16, 2020 03:00
JCM, Vol. 9, Pages 3330: Immediate Effect of Masticatory Muscle Activity with Transcutaneous Electrical Nerve Stimulation in Muscle Pain of Temporomandibular Disorders Patients Journal of Clinical Medicine doi: 10.3390/jcm9103330 Authors: Abe Miyagi Yoshinaga Matsuka Matsumoto Uyama Suzuki Oshima Okura Tanaka Transcutaneous electrical nerve stimulation (TENS) is a non-invasive treatment modality for acute and chronic pain. However, little information...
Fri Oct 16, 2020 03:00
JCM, Vol. 9, Pages 3328: The Impact of Experience, Length of Service, and Workplace Preparedness in Physicians’ Readiness in the Response to Disasters Journal of Clinical Medicine doi: 10.3390/jcm9103328 Authors: Krzysztof Goniewicz Mariusz Goniewicz Frederick M. Burkle Amir Khorram-Manesh With an increasing number of natural and man-made disasters, the need for preparedness in all levels of management is obvious. Among healthcare professionals responding to these emergencies,...
Fri Oct 16, 2020 03:00
JCM, Vol. 9, Pages 3327: The Metabolic Rearrangements of Bariatric Surgery: Focus on Orexin-A and the Adiponectin System Journal of Clinical Medicine doi: 10.3390/jcm9103327 Authors: Anna Valenzano Nicola Tartaglia Antonio Ambrosi Domenico Tafuri Marcellino Monda Antonietta Messina Francesco Sessa Angelo Campanozzi Vincenzo Monda Giuseppe Cibelli Giovanni Messina Rita Polito The accumulation of adipose tissue represents one of the characteristics of obesity,...
Fri Oct 16, 2020 03:00
JCM, Vol. 9, Pages 3325: In Vitro Evaluation of Different Irrigation Protocols on Intracanal Smear Layer Removal in Teeth with or without Pre-Endodontic Proximal Wall Restoration Journal of Clinical Medicine doi: 10.3390/jcm9103325 Authors: Naji Kharouf Eugenio Pedullà Giusy Rita Maria La Rosa Frédéric Bukiet Salvatore Sauro Youssef Haikel Davide Mancino To investigate the influence of pre-endodontic coronal wall restoration on smear layer removal during different root...
Fri Oct 16, 2020 03:00
JCM, Vol. 9, Pages 3326: A Comparison of Case Fatality Risk of COVID-19 between Singapore and Japan Journal of Clinical Medicine doi: 10.3390/jcm9103326 Authors: Taishi Kayano Hiroshi Nishiura The crude case fatality risk (CFR) for coronavirus disease (COVID-19) in Singapore is remarkably small. We aimed to estimate the unbiased CFR by age for Singapore and Japan and compare these estimates by calculating the standardized mortality ratio (SMR). Age-specific CFRs for COVID-19 were...
Fri Oct 16, 2020 03:00
JCM, Vol. 9, Pages 3323: Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy Journal of Clinical Medicine doi: 10.3390/jcm9103323 Authors: Motedayen Aval Pease Sharma Pinato Immune checkpoint inhibitors (ICI) have revolutionised cancer therapy. However, they have been effective in only a small subset of patients and a principal mechanism underlying immune-refractoriness is a ‘cold’ tumour microenvironment,...
Fri Oct 16, 2020 03:00
JCM, Vol. 9, Pages 3324: Iridoschisis—A Systematic Review Journal of Clinical Medicine doi: 10.3390/jcm9103324 Authors: Barbara Pieklarz Emil Tomasz Grochowski Emil Saeed Patryk Sidorczuk Zofia Mariak Diana Anna Dmuchowska Iridoschisis is a rare condition defined as a separation of the anterior iris stroma from the posterior stroma and muscle layers. In this paper, we review current data about the epidemiology, pathophysiology, clinical characteristics and differential...
Fri Oct 16, 2020 03:00
JCM, Vol. 9, Pages 3322: Diabetic Cardiovascular Autonomic Neuropathy, the Handgrip Test and Ambulatory Blood Pressure Monitoring Parameters: Are There Any Diagnostic Implications? Journal of Clinical Medicine doi: 10.3390/jcm9103322 Authors: Miklós Kempler Noémi Hajdú Zsuzsanna Putz Ildikó Istenes Orsolya Vági Magdolna Békeffy Karolina Schnabel Péter Kempler Anna E. Körei Cardiovascular autonomic neuropathy (CAN) is a common complication of diabetes mellitus....
Fri Oct 16, 2020 03:00
JCM, Vol. 9, Pages 3321: Infrapopliteal Artery Occlusive Disease: An Overview of Vessel Preparation and Treatment Options Journal of Clinical Medicine doi: 10.3390/jcm9103321 Authors: Srini Tummala Ayush Amin Ankit Mehta Critical limb ischemia (CLI) is defined as chronic rest pain and/or the presence of tissue loss (ulcers or gangrene) in the lower extremities secondary to ischemia. CLI is a limb and potentially life-threatening disease associated with a poor prognosis with only...
Fri Oct 16, 2020 03:00
JCM, Vol. 9, Pages 3320: The Long-Term Effect of Adapting the Vertical Position of Implants on Peri-Implant Health: A 5-Year Intra-Subject Comparison in the Edentulous Mandible Including Oral Health-Related Quality of Life Journal of Clinical Medicine doi: 10.3390/jcm9103320 Authors: Ron Doornewaard Hugo de Bruyn Carine Matthys Ewald Bronkhorst Stefan Vandeweghe Stijn Vervaeke Despite high success rates of dental implants, surface exposure may occur as a consequence of...
Fri Oct 16, 2020 03:00
JCM, Vol. 9, Pages 3319: Therapeutic Maintenance of Baricitinib and Tofacitinib in Real Life Journal of Clinical Medicine doi: 10.3390/jcm9103319 Authors: Valentine Deprez Laure Le Monnier Jean-Marc Sobhy-Danial Franck Grados Isabelle Henry-Desailly Sarah Salomon-Goëb Thibault Rabin Sanja Ristic Mathurin Fumery Patrice Fardellone Vincent Goëb Background: Janus kinase inhibitors (JAKis) represent a new alternative to treat rheumatoid arthritis (RA). The objective...
Fri Oct 16, 2020 03:00
JFB, Vol. 11, Pages 75: Novel Orthodontic Cement Comprising Unique Imidazolium-Based Polymerizable Antibacterial Monomers Journal of Functional Biomaterials doi: 10.3390/jfb11040075 Authors: Hui Lu Xiaoming Jin White spot lesions (WSLs) can develop quickly and compromise the successful outcome of the orthodontic treatment. Orthodontic bonding cement with the capability to prevent or mitigate WSLs could be beneficial, especially for patients with high risk of caries. This study explored...
Sat Oct 17, 2020 03:00
JoF, Vol. 6, Pages 232: Insights into the Gryllus bimaculatus Immune-Related Transcriptomic Profiling to Combat Naturally Invading Pathogens Journal of Fungi doi: 10.3390/jof6040232 Authors: Abid Hussain Muhammad Waqar Ali Ahmed Mohammed AlJabr Saad Naser AL-Kahtani Natural pathogen pressure is an important factor that shapes the host immune defense mechanism. The current study primarily aimed to explore the molecular basis of the natural immune defense mechanism of a sporadic...
Sun Oct 18, 2020 03:00
JoF, Vol. 6, Pages 231: Using Expanded Natural Killer Cells as Therapy for Invasive Aspergillosis Journal of Fungi doi: 10.3390/jof6040231 Authors: Win Mar Soe Joan Hui Juan Lim David L. Williams Jessamine Geraldine Goh Zhaohong Tan Qi Hui Sam Sanjay H. Chotirmall Nur A’tikah Binte Mohamed Ali Soo Chin Lee Ju Ee Seet Sharada Ravikumar Louis Yi Ann Chai Invasive aspergillosis (IA) is a major opportunistic fungal infection in patients with haematological...
Sat Oct 17, 2020 03:00
JoF, Vol. 6, Pages 230: Characterization of a Candida albicans Mutant Defective in All MAPKs Highlights the Major Role of Hog1 in the MAPK Signaling Network Journal of Fungi doi: 10.3390/jof6040230 Authors: Inês Correia Duncan Wilson Bernhard Hube Jesús Pla The success of Candida albicans as a pathogen relies on its ability to adapt and proliferate in different environmental niches. Pathways regulated by mitogen-activated protein kinases (MAPKs) are involved in sensing environmental...
Sat Oct 17, 2020 03:00
JoF, Vol. 6, Pages 229: Metabolites from Clonostachys Fungi and Their Biological Activities Journal of Fungi doi: 10.3390/jof6040229 Authors: Han Zhang Xu Zhang Lai Zhou Clonostachys (teleomorph: Bionectria) fungi are well known to produce a variety of secondary metabolites with various biological activities to show their pharmaceutical and agrochemical applications. Up to now, at least 229 secondary metabolites, mainly including 84 nitrogen-containing metabolites,...
Fri Oct 16, 2020 03:00
JoF, Vol. 6, Pages 226: Invasive Mold Infection of the Central Nervous System in Immunocompromised Children Journal of Fungi doi: 10.3390/jof6040226 Authors: Luciana Porto Se-Jong You Andishe Attarbaschi Gunnar Cario Michaela Döring Olga Moser Urs Mücke Fiona Poyer Christian Temme Sebastian Voigt Andreas H. Groll Melchior Lauten Elke Hattingen Thomas Lehrnbecher Background: Due to the difficulties in the definite diagnosis, data on brain imaging...
Fri Oct 16, 2020 03:00
JoF, Vol. 6, Pages 228: Genetic Response of Common Bean to the Inoculation with Indigenous Fusarium Isolates Journal of Fungi doi: 10.3390/jof6040228 Authors: Porteous-Álvarez Mayo-Prieto Álvarez-García Reinoso Casquero Fungal species from the genus Fusarium are important soil-borne pathogens worldwide, causing significant economic losses in diverse crops. The need to find sustainable solutions against this disease has led to the development of new strategies—for...
Fri Oct 16, 2020 03:00
JoF, Vol. 6, Pages 227: Hmg1 Gene Mutation Prevalence in Triazole-Resistant Aspergillus fumigatus Clinical Isolates Journal of Fungi doi: 10.3390/jof6040227 Authors: Agustin Resendiz-Sharpe Margriet W.J. Hokken Toine Mercier Rita Merckx Kamiel Verhagen Lisa Dewitte Willem J.G. Melchers Paul E. Verweij Johan Maertens Katrien Lagrou Recently, mutations in the 3-hydroxy-3-methylglutaryl-coenzyme-A-reductase-encoding gene (hmg1), a gene involved in ergosterol production,...
Fri Oct 16, 2020 03:00
JoF, Vol. 6, Pages 225: Perinuclear Anti-Neutrophil Cytoplasmic Antibodies (pANCA) Impair Neutrophil Candidacidal Activity and Are Increased in the Cellular Fraction of Vaginal Samples from Women with Vulvovaginal Candidiasis Journal of Fungi doi: 10.3390/jof6040225 Authors: Andrea Ardizzoni Arianna Sala Bruna Colombari Lavinia Beatrice Giva Claudio Cermelli Samuele Peppoloni Anna Vecchiarelli Elena Roselletti Elisabetta Blasi Robert T. Wheeler Eva Pericolini...
Fri Oct 16, 2020 03:00
J. Imaging, Vol. 6, Pages 111: An Automated Method for Quality Control in MRI Systems: Methods and Considerations Journal of Imaging doi: 10.3390/jimaging6100111 Authors: Epistatou Tsalafoutas Delibasis Objective: The purpose of this study was to develop an automated method for performing quality control (QC) tests in magnetic resonance imaging (MRI) systems, investigate the effect of different definitions of QC parameters and its sensitivity with respect to variations in regions...
Sun Oct 18, 2020 03:00
J. Imaging, Vol. 6, Pages 110: Deep Learning for Historical Document Analysis and Recognition—A Survey Journal of Imaging doi: 10.3390/jimaging6100110 Authors: Francesco Lombardi Simone Marinai Nowadays, deep learning methods are employed in a broad range of research fields. The analysis and recognition of historical documents, as we survey in this work, is not an exception. Our study analyzes the papers published in the last few years on this topic from different perspectives: we...
Fri Oct 16, 2020 03:00
JPM, Vol. 10, Pages 178: Modelling Neuromuscular Diseases in the Age of Precision Medicine Journal of Personalized Medicine doi: 10.3390/jpm10040178 Authors: Alfina A. Speciale Ruth Ellerington Thomas Goedert Carlo Rinaldi Advances in knowledge resulting from the sequencing of the human genome, coupled with technological developments and a deeper understanding of disease mechanisms of pathogenesis are paving the way for a growing role of precision medicine in the treatment of...
Sat Oct 17, 2020 03:00
JPM, Vol. 10, Pages 177: Local Disease-Free Survival Rate (LSR) Application to Personalize Radiation Therapy Treatments in Breast Cancer Models Journal of Personalized Medicine doi: 10.3390/jpm10040177 Authors: Savoca Calvaruso Minafra Bravatà Cammarata Iacoviello Abbate Evangelista Spada Forte Russo Cancer heterogeneity represents the main issue for defining an effective treatment in clinical practice, and the scientific community is progressively...
Sat Oct 17, 2020 03:00
JPM, Vol. 10, Pages 175: Could Fecal Microbiota Be a Useful Indicator of Serum Cholesterol Levels among Men? Journal of Personalized Medicine doi: 10.3390/jpm10040175 Authors: HuiJun Chih Stuart C. Smith Ramon S. Hall Stuart K. Johnson Trepidation with blood tests among men may result in fewer routine screening and examination of their cardiovascular risk factors. Associations between fecal microbiota and serum cholesterols have not been well-established. The aim of this study...
Fri Oct 16, 2020 03:00
JPM, Vol. 10, Pages 176: Effects of Two Community-Based Exercise Programs on Adherence, Cardiometabolic Markers, and Body Composition in Older People with Cardiovascular Risk Factors: A Prospective Observational Cohort Study Journal of Personalized Medicine doi: 10.3390/jpm10040176 Authors: García-Sánchez Rubio-Arias Ávila-Gandía López-Román Menarguez-Puche Cardiovascular disease is one of the leading causes of death globally, and cardiovascular risk factors (CRFs) are...
Fri Oct 16, 2020 03:00
JPM, Vol. 10, Pages 174: Personalisation of Molecular Radiotherapy through Optimisation of Theragnostics Journal of Personalized Medicine doi: 10.3390/jpm10040174 Authors: LauraMay Davis April-Louise Smith Matthew D. Aldridge Jack Foulkes Connie Peet Simon Wan Jennifer E. Gains Jamshed B. Bomanji Mark N. Gaze Molecular radiotherapy, or targeted radionuclide therapy, uses systemically administered drugs bearing a suitable radioactive isotope, typically a beta emitter....
Fri Oct 16, 2020 03:00
JPM, Vol. 10, Pages 173: Prognostic Impact of the Neutrophil-to-Lymphocyte and Lymphocyte-to-Monocyte Ratio, in Patients with Rectal Cancer: A Retrospective Study of 1052 Patients Journal of Personalized Medicine doi: 10.3390/jpm10040173 Authors: Zsolt Zoltán Fülöp Simona Gurzu Réka Linda Fülöp Tivadar Bara József Tímár Emőke Drágus Ioan Jung Despite the description of several new prognostic markers, colorectal cancer still represents the third most frequent cause of...
Fri Oct 16, 2020 03:00
Life, Vol. 10, Pages 247: Right Heart Changes Impact on Clinical Phenotype of Amyloid Cardiac Involvement: A Single Centre Study Life doi: 10.3390/life10100247 Authors: Sebastiano Cicco Antonio Giovanni Solimando Roberta Buono Nicola Susca Gianfranco Inglese Assunta Melaccio Marcella Prete Roberto Ria Vito Racanelli Angelo Vacca Amyloidosis is due to deposition of an excessive amount of protein in many parenchymal tissues, including myocardium. The onset of...
Sun Oct 18, 2020 03:00
Life, Vol. 10, Pages 246: Alterations of Specific Lymphocytic Subsets with Aging and Age-Related Metabolic and Cardiovascular Diseases Life doi: 10.3390/life10100246 Authors: Ying Jen Chen Yi Jen Liao Van Thi Ngoc Tram Chung Hao Lin Kuo Chen Liao Chao Lien Liu To investigate the association of immunosenescence with aged-related morbidity in the elderly, a clinical study was conducted to analyze and compare the alterations in peripheral blood (PB) T-cell subsets among young...
Sat Oct 17, 2020 03:00
Life, Vol. 10, Pages 245: Deregulated Serotonin Pathway in Women with Morbid Obesity and NAFLD Life doi: 10.3390/life10100245 Authors: Binetti Bertran Riesco Aguilar Martínez Sabench Porras Camaron Castillo Richart Auguet Non-alcoholic fatty liver disease (NAFLD) extends from simple steatosis (SS) to non-alcoholic steatohepatitis (NASH). Peripheral serotonin (5-HT) has become as an important regulator of different metabolic pathways. 5-HT has...
Fri Oct 16, 2020 03:00
Life, Vol. 10, Pages 244: Is Malignant Potential of Barrett’s Esophagus Predictable by Endoscopy Findings? Life doi: 10.3390/life10100244 Authors: Amano Ishimura Ishihara Given that endoscopic findings can be used to predict the potential of neoplastic progression in Barrett’s esophagus (BE) cases, the detection rate of dysplastic Barrett’s lesions may become higher even in laborious endoscopic surveillance because a special attention is consequently paid....
Fri Oct 16, 2020 03:00
Medicina, Vol. 56, Pages 546: A Comparison of Clinical Outcomes between Endoscopic Resection and Surgical Resection in Ampullary Tumors Medicina doi: 10.3390/medicina56100546 Authors: Jung-Soo Pyo Byoung Kwan Son Hyo Young Lee Il Hwan Oh Kwang Hyun Chung Background and objectives: This study aimed to elucidate the clinical outcomes of endoscopic resection (ER) through comparison with surgical resection (SR) through a meta-analysis. Materials and Methods: This meta-analysis...
Sun Oct 18, 2020 03:00
Medicina, Vol. 56, Pages 544: Silymarin in Combination with Vitamin C, Vitamin E, Coenzyme Q10 and Selenomethionine to Improve Liver Enzymes and Blood Lipid Profile in NAFLD Patients Medicina doi: 10.3390/medicina56100544 Authors: Annalisa Curcio Adriana Romano Simona Cuozzo Antonio Di Nicola Orazio Grassi Donatella Schiaroli Giuseppe Fabrizio Nocera Michele Pironti Background and Objectives: Non-Alcoholic Fatty Liver Disease (NAFLD) is an emerging cause of hepatopathy...
Sat Oct 17, 2020 03:00
Medicina, Vol. 56, Pages 545: Modestly Elevated Serum Procalcitonin Levels in Patients with Rheumatoid Arthritis Free of Active Infection Medicina doi: 10.3390/medicina56100545 Authors: Khai-Jing Ng Hui-Chun Yu Hsien-Yu Huang Tseng Chia-Wen Hsu Ming-Chi Lu Background and objectives: To investigate the serum procalcitonin (PCT) levels among patients with rheumatoid arthritis (RA) without active infection compared with healthy controls and to understand the relationship of...
Sat Oct 17, 2020 03:00
Medicina, Vol. 56, Pages 543: Heat-Related Illnesses Transported by United States Emergency Medical Services Medicina doi: 10.3390/medicina56100543 Authors: Susan Yeargin Rebecca Hirschhorn Andrew Grundstein Background and objectives: Heat-related illness (HRI) can have significant morbidity and mortality consequences. Research has predominately focused on HRI in the emergency department, yet health care leading up to hospital arrival can impact patient outcomes. Therefore, the...
Sat Oct 17, 2020 03:00
Membranes, Vol. 10, Pages 293: Enhanced Fouling Resistance and Antimicrobial Property of Ultrafiltration Membranes Via Polyelectrolyte-Assisted Silver Phosphate Nanoparticle Immobilization Membranes doi: 10.3390/membranes10100293 Authors: Kunal Olimattel Jared Church Woo Hyoung Lee Karin Y. Chumbimuni-Torres Lei Zhai A H M Anwar Sadmani Ultrafiltration (UF) is a low-pressure membrane that yields higher permeate flux and saves significant operating costs compared to high-pressure...
Sat Oct 17, 2020 03:00
Membranes, Vol. 10, Pages 292: Graphene Oxide-Based Membranes for Water Purification Applications: Effect of Plasma Treatment on the Adhesion and Stability of the Synthesized Membranes Membranes doi: 10.3390/membranes10100292 Authors: Omer Alnoor Tahar Laoui Ahmed Ibrahim Feras Kafiah Ghaith Nadhreen Sultan Akhtar Zafarullah Khan The adhesion enhancement of graphene oxide (GO) and reduced graphene oxide (rGO) layer in the underlying polyethersulfone (PES) microfiltration...
Sat Oct 17, 2020 03:00
Membranes, Vol. 10, Pages 291: Flux-Reducing Tendency of Pd-Based Membranes Employed in Butane Dehydrogenation Processes Membranes doi: 10.3390/membranes10100291 Authors: Thijs A. Peters Marit Stange Rune Bredesen We report on the effect of butane and butylene on hydrogen permeation through thin state-of-the-art Pd–Ag alloy membranes. A wide range of operating conditions, such as temperature (200–450 °C) and H2/butylene (or butane) ratio (0.5–3),...
Fri Oct 16, 2020 03:00
Membranes, Vol. 10, Pages 290: Fabrication of Bentonite–Silica Sand/Suspended Waste Palm Leaf Composite Membrane for Water Purification Membranes doi: 10.3390/membranes10100290 Authors: Saad A. Aljlil In this study, a method for fabricating tubular ceramic membranes via extrusion using economical and locally available bentonite–silica sand and waste palm leaves was developed as a tool for conducting the necessary task of purifying water polluted with oil and suspended solid...
Fri Oct 16, 2020 03:00
Metabolites, Vol. 10, Pages 417: The Peptide Chain Release Factor Methyltransferase PrmC Influences the Pseudomonas aeruginosa PA14 Endo- and Exometabolome Metabolites doi: 10.3390/metabo10100417 Authors: Tobias Depke Susanne Häussler Mark Brönstrup Pseudomonas aeruginosa is one of the most important nosocomial pathogens and understanding its virulence is the key to effective control of P. aeruginosa infections. The regulatory network governing virulence factor production in P....
Sun Oct 18, 2020 03:00
Metabolites, Vol. 10, Pages 416: A Python-Based Pipeline for Preprocessing LC–MS Data for Untargeted Metabolomics Workflows Metabolites doi: 10.3390/metabo10100416 Authors: Gabriel Riquelme Nicolás Zabalegui Pablo Marchi Christina M. Jones María Eugenia Monge Preprocessing data in a reproducible and robust way is one of the current challenges in untargeted metabolomics workflows. Data curation in liquid chromatography–mass spectrometry (LC–MS) involves...
Fri Oct 16, 2020 03:00
Metabolites, Vol. 10, Pages 415: Rapid Preparation of a Large Sulfated Metabolite Library for Structure Validation in Human Samples Metabolites doi: 10.3390/metabo10100415 Authors: Mario S. P. Correia Weifeng Lin Arash J. Aria Abhishek Jain Daniel Globisch Metabolomics analysis of biological samples is widely applied in medical and natural sciences. Assigning the correct chemical structure in the metabolite identification process is required to draw the correct biological...
Fri Oct 16, 2020 03:00
Metabolites, Vol. 10, Pages 414: Antioxidant and Antibacterial Capacities of Origanum vulgare L. Essential Oil from the Arid Andean Region of Chile and its Chemical Characterization by GC-MS Metabolites doi: 10.3390/metabo10100414 Authors: Mario J. Simirgiotis Daniel Burton Felipe Parra Jéssica López Patricio Muñoz Hugo Escobar Claudio Parra This study aimed to characterize the in vitro antioxidant and antibacterial properties of oregano (Origanum vulgare) essential...
Fri Oct 16, 2020 03:00
Microorganisms, Vol. 8, Pages 1605: Effects of Wormwood (Artemisia montana) Essential Oils on Digestibility, Fermentation Indices, and Microbial Diversity in the Rumen Microorganisms doi: 10.3390/microorganisms8101605 Authors: Lee Kim Paradhipta Lee Yoon Joo Adesogan Kim This study investigated the effects of essential oil (EO) from three Korean wormwood (Artemisia Montana) plants on in vitro ruminal digestibility, fermentation, and microbial diversity. Dried...
Sun Oct 18, 2020 03:00
Microorganisms, Vol. 8, Pages 1603: Combined Comparative Genomics and Gene Expression Analyses Provide Insights into the Terpene Synthases Inventory in Trichoderma Microorganisms doi: 10.3390/microorganisms8101603 Authors: Isabel Vicente Riccardo Baroncelli María Eugenia Morán-Diez Rodolfo Bernardi Grazia Puntoni Rosa Hermosa Enrique Monte Giovanni Vannacci Sabrina Sarrocco Trichoderma is a fungal genus comprising species used as biocontrol agents in crop plant...
Sun Oct 18, 2020 03:00
Microorganisms, Vol. 8, Pages 1602: A Preliminary Study on the Presence of Salmonella in Lymph Nodes of Sows at Processing Plants in the United States Microorganisms doi: 10.3390/microorganisms8101602 Authors: Roger B. Harvey Keri N. Norman Robin C. Anderson David J. Nisbet Salmonella-contaminated lymph nodes (LN), when included into edible meat products, are a potential source of Salmonella foodborne disease. In this survey, ventral superficial cervical and mandibular LN were...
Sun Oct 18, 2020 03:00
Microorganisms, Vol. 8, Pages 1601: Bacterial Community Dynamics Distinguish Poultry Compost from Dairy Compost and Non-Amended Soils Planted with Spinach Microorganisms doi: 10.3390/microorganisms8101601 Authors: Deborah A. Neher Marie A. Limoges Thomas R. Weicht Manan Sharma Patricia D. Millner Catherine Donnelly The aim of this study was to determine whether and how poultry litter compost and dairy manure compost alter the microbial communities within field soils planted...
Sun Oct 18, 2020 03:00
Microorganisms, Vol. 8, Pages 1604: Spatial Changes in Microbial Communities along Different Functional Zones of a Free-Water Surface Wetland Microorganisms doi: 10.3390/microorganisms8101604 Authors: Mikhail V. Semenov George S. Krasnov Ksenia Y. Rybka Sergey L. Kharitonov Yulia A. Zavgorodnyaya Anna V. Yudina Nataliya M. Shchegolkova Constructed wetlands (CWs) are complicated ecosystems that include vegetation, sediments, and the associated microbiome mediating numerous...
Sun Oct 18, 2020 03:00
Microorganisms, Vol. 8, Pages 1600: In silico Investigation on the Inhibiting Role of Nicotine/Caffeine by Blocking the S Protein of SARS-CoV-2 Versus ACE2 Receptor Microorganisms doi: 10.3390/microorganisms8101600 Authors: Saeedeh Mohammadi Mohammad Heidarizadeh Mehrnaz Entesari Ayoub Esmailpour Mohammad Esmailpour Rasoul Moradi Nader Sakhaee Esmail Doustkhah In this paper, we studied the in silico interaction of angiotensin-converting enzyme 2 (ACE2) human receptor...
Sat Oct 17, 2020 03:00
Microorganisms, Vol. 8, Pages 1598: Crucial Role of the C-Terminal Domain of Hfq Protein in Genomic Instability Microorganisms doi: 10.3390/microorganisms8101598 Authors: Virali J. Parekh Frank Wien Wilfried Grange Thomas A. De Long Véronique Arluison Richard R. Sinden G-rich DNA repeats that can form G-quadruplex structures are prevalent in bacterial genomes and are frequently associated with regulatory regions of genes involved in virulence, antigenic variation, and...
Sat Oct 17, 2020 03:00
Microorganisms, Vol. 8, Pages 1599: Identification and Elimination of the Clinically Relevant Multi-Resistant Environmental Bacteria Ralstonia insidiosa in Primary Cell Culture Microorganisms doi: 10.3390/microorganisms8101599 Authors: Dennis Nurjadi Sébastien Boutin Katja Schmidt Melinda Ahmels Daniel Hasche In times of spreading multidrug-resistant bacteria, species identification and decontamination of cell cultures can be challenging. Here, we describe a mobile cell culture...
Sat Oct 17, 2020 03:00
Microorganisms, Vol. 8, Pages 1595: American Crows as Carriers of Extra Intestinal Pathogenic E. coli and Avian Pathogenic-Like E. coli and Their Potential Impact on a Constructed Wetland Microorganisms doi: 10.3390/microorganisms8101595 Authors: Keya Sen Vaughn Shepherd Tanner Berglund Alexa Quintana Shnia Puim Rama Tadmori Robert J. Turner Laura Khalil Marilia A. Soares The study examines whether crows are carriers of extraintestinal pathogenic E. coli (ExPEC)...
Fri Oct 16, 2020 03:00
Microorganisms, Vol. 8, Pages 1593: First Detection of GES-5-Producing Escherichia coli from Livestock—An Increasing Diversity of Carbapenemases Recognized from German Pig Production Microorganisms doi: 10.3390/microorganisms8101593 Authors: Alexandra Irrgang Simon H. Tausch Natalie Pauly Mirjam Grobbel Annemarie Kaesbohrer Jens A. Hammerl Resistance to carbapenems due to carbapenemase-producing Enterobacteriaceae (CPE) is an increasing threat to human health worldwide....
Fri Oct 16, 2020 03:00
Microorganisms, Vol. 8, Pages 1596: Isolation and Identification of Potentially Pathogenic Microorganisms Associated with Dental Caries in Human Teeth Biofilms Microorganisms doi: 10.3390/microorganisms8101596 Authors: Xiuqin Chen Eric Banan-Mwine Daliri Ramachandran Chelliah Deog-Hwan Oh Dental caries is attributed to the predominance of cariogenic microorganisms. Cariogenic microorganisms are pathological factors leading to acidification of the oral microenvironment, which...
Fri Oct 16, 2020 03:00
Microorganisms, Vol. 8, Pages 1594: Understanding High-Salt and Cold Adaptation of a Polyextremophilic Enzyme Microorganisms doi: 10.3390/microorganisms8101594 Authors: Ram Karan Sam Mathew Reyhan Muhammad Didier B. Bautista Malvina Vogler Jorg Eppinger Romina Oliva Luigi Cavallo Stefan T. Arold Magnus Rueping The haloarchaeon Halorubrum lacusprofundi is among the few polyextremophilic organisms capable of surviving in one of the most extreme aquatic environments...
Fri Oct 16, 2020 03:00
Microorganisms, Vol. 8, Pages 1597: Tularemia Goes West: Epidemiology of an Emerging Infection in Austria Microorganisms doi: 10.3390/microorganisms8101597 Authors: Stefanie Seiwald Anja Simeon Erwin Hofer Günter Weiss Rosa Bellmann-Weiler The zoonotic disease tularemia is caused by the Gram-negative bacterium Francisella tularensis, with the two major subspecies tularensis and holarctica being responsible for infections in humans and animals. The F. tularensis subspecies...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4785: Chitosan-Based Biomimetically Mineralized Composite Materials in Human Hard Tissue Repair Molecules doi: 10.3390/molecules25204785 Authors: Die Hu Qian Ren Zhongcheng Li Linglin Zhang Chitosan is a natural, biodegradable cationic polysaccharide, which has a similar chemical structure and similar biological behaviors to the components of the extracellular matrix in the biomineralization process of teeth or bone. Its excellent biocompatibility,...
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Molecules, Vol. 25, Pages 4784: Optimization of Fungal Dextranase Production and Its Antibiofilm Activity, Encapsulation and Stability in Toothpaste Molecules doi: 10.3390/molecules25204784 Authors: Juntarachot Kantachote Peerajan Sirilun Chaiyasut Dextranase catalyzes the degradation of the substrate dextran, which is a component of plaque biofilm. This enzyme is involved in antiplaque accumulation, which can prevent dental caries. The activity of crude dextranase from...
Sun Oct 18, 2020 03:00
Molecules, Vol. 25, Pages 4783: Combining Experimental Data and Computational Methods for the Non-Computer Specialist Molecules doi: 10.3390/molecules25204783 Authors: Reinier Cárdenas Javier Martínez-Seoane Carlos Amero Experimental methods are indispensable for the study of the function of biological macromolecules, not just as static structures, but as dynamic systems that change conformation, bind partners, perform reactions, and respond to different stimulus. However, providing...
Sun Oct 18, 2020 03:00
Molecules, Vol. 25, Pages 4781: Preparation of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Drug Delivery and the Effects of Preparation Parameters of Solvent Injection Method Molecules doi: 10.3390/molecules25204781 Authors: Van-An Duong Thi-Thao-Linh Nguyen Han-Joo Maeng Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have emerged as potential drug delivery systems for various applications that are produced from physiological, biodegradable,...
Sun Oct 18, 2020 03:00
Molecules, Vol. 25, Pages 4782: Simultaneous Qualitative and Quantitative Evaluation of the Coptidis Rhizoma and Euodiae Fructus Herbal Pair by Using UHPLC-ESI-QTOF-MS and UHPLC-DAD Molecules doi: 10.3390/molecules25204782 Authors: Yan-Ying Li Min-Qun Guo Xue-Mei Li Xiu-Wei Yang The herbal pair of Coptidis Rhizoma (CR) and Euodiae Fructus (EF) is a classical traditional Chinese medicine formula used for treating gastro-intestinal disorders. In this study, we established a systematic...
Sun Oct 18, 2020 03:00
Molecules, Vol. 25, Pages 4780: Synthesis, In Silico and In Vitro Assessment of New Quinazolinones as Anticancer Agents via Potential AKT Inhibition Molecules doi: 10.3390/molecules25204780 Authors: Noser El-Naggar Donia Abdelmonsef A series of novel quinazolinone derivatives (2–13) was synthesized and examined for their cytotoxicity to HepG2, MCF-7, and Caco-2 in an MTT assay. Among these derivatives, compounds 4 and 9 exhibited significant cytotoxic activity...
Sun Oct 18, 2020 03:00
Molecules, Vol. 25, Pages 4779: [Bmim]Br Accelerated One-Pot Three-Component Cascade Protocol for the Construction of Spirooxindole–Pyrrolidine Heterocyclic Hybrids Molecules doi: 10.3390/molecules25204779 Authors: Raju Suresh Kumar Dhaifallah M. Al-thamili Abdulrahman I. Almansour Natarajan Arumugam Necmi Dege Our synthetic approach for the assembly of structurally complex spirooxindole heterocyclic hybrids was based on an ionic liquid, [bmim]Br mediated one-pot three-component...
Sun Oct 18, 2020 03:00
Molecules, Vol. 25, Pages 4778: Isolation and Structure Determination of Echinochrome A Oxidative Degradation Products Molecules doi: 10.3390/molecules25204778 Authors: Natalia P. Mishchenko Elena A. Vasileva Andrey V. Gerasimenko Valeriya P. Grigorchuk Pavel S. Dmitrenok Sergey A. Fedoreyev Echinochrome A (Ech A, 1) is one of the main pigments of several sea urchin species and is registered in the Russian pharmacopeia as an active drug substance (Histochrome®),...
Sun Oct 18, 2020 03:00
Molecules, Vol. 25, Pages 4773: Green Synthesis of Gold and Silver Nanoparticles by Using Amorphophallus paeoniifolius Tuber Extract and Evaluation of Their Antibacterial Activity Molecules doi: 10.3390/molecules25204773 Authors: S. M. Abu Nayem Nasrin Sultana Md. Aminul Haque Billal Miah Md. Mahmodul Hasan Tamanna Islam Md. Mahedi Hasan Abdul Awal Jamal Uddin Md. Abdul Aziz A. J. Saleh Ahammad In this report, we discussed rapid, facile one-pot green synthesis...
Sun Oct 18, 2020 03:00
Molecules, Vol. 25, Pages 4777: Plasma and Urinary (Poly)phenolic Profiles after 4-Week Red Raspberry (Rubus idaeus L.) Intake with or without Fructo-Oligosaccharide Supplementation Molecules doi: 10.3390/molecules25204777 Authors: Xuhuiqun Zhang Amandeep Sandhu Indika Edirisinghe Britt M. Burton-Freeman Red raspberries (RRB) are high in anthocyanin- and ellagitannin- type (poly)phenols. This study aimed to investigate the effect of 4-week RRB supplementation on (poly)phenolic...
Sat Oct 17, 2020 03:00
Molecules, Vol. 25, Pages 4776: Mass Spectrometric Analysis of Antibody—Epitope Peptide Complex Dissociation: Theoretical Concept and Practical Procedure of Binding Strength Characterization Molecules doi: 10.3390/molecules25204776 Authors: Bright D. Danquah Kwabena F. M. Opuni Claudia Roewer Cornelia Koy Michael O. Glocker Electrospray mass spectrometry is applied to determine apparent binding energies and quasi equilibrium dissociation constants of immune complex dissociation...
Sat Oct 17, 2020 03:00
Molecules, Vol. 25, Pages 4775: Current Status of Matrix-Assisted Laser Desorption/Ionization–Time-of-Flight Mass Spectrometry (MALDI-TOF MS) in Clinical Diagnostic Microbiology Molecules doi: 10.3390/molecules25204775 Authors: Sachio Tsuchida Hiroshi Umemura Tomohiro Nakayama Mass spectrometry (MS), a core technology for proteomics and metabolomics, is currently being developed for clinical applications. The identification of microorganisms in clinical samples using matrix-assisted...
Sat Oct 17, 2020 03:00
Molecules, Vol. 25, Pages 4774: Synthesis of Block Copolymer Brush by RAFT and Click Chemistry and Its Self-Assembly as a Thin Film Molecules doi: 10.3390/molecules25204774 Authors: Hajeeth Thankappan Mona Semsarilar Suming Li Yung Chang Denis Bouyer Damien Quemener A well-defined block copolymer brush poly(glycidyl methacrylate)-graft-(poly(methyl methacrylate)-block- poly(oligo(ethylene glycol) methyl ether methacrylate)) (PGMA-g-(PMMA-b-POEGMA)) is synthesized via grafting...
Sat Oct 17, 2020 03:00
Molecules, Vol. 25, Pages 4771: Two-Step One-Pot Reductive Amination of Furanic Aldehydes Using CuAlOx Catalyst in a Flow Reactor Molecules doi: 10.3390/molecules25204771 Authors: Alexey L. Nuzhdin Marina V. Bukhtiyarova Valerii I. Bukhtiyarov Aminomethylhydroxymethylfuran derivatives are well known compounds which are used in the pharmaceutical industry. Reductive amination of 5-hydroxymethylfurfural (HMF) derived from available non-edible lignocellulosic biomass is an attractive...
Sat Oct 17, 2020 03:00
Molecules, Vol. 25, Pages 4772: Association of Moderate Beer Consumption with the Gut Microbiota and SCFA of Healthy Adults Molecules doi: 10.3390/molecules25204772 Authors: Natalia González-Zancada Noemí Redondo-Useros Ligia E. Díaz Sonia Gómez-Martínez Ascensión Marcos Esther Nova Fermented alcoholic drinks’ contribution to the gut microbiota composition is mostly unknown. However, intestinal microorganisms can use compounds present in beer. This work explored...
Sat Oct 17, 2020 03:00
Molecules, Vol. 25, Pages 4770: Antibacterial Activity of Honey/Chitosan Nanofibers Loaded with Capsaicin and Gold Nanoparticles for Wound Dressing Molecules doi: 10.3390/molecules25204770 Authors: Sharafaldin Al-Musawi Salim Albukhaty Hassan Al-Karagoly Ghassan M. Sulaiman Mona S. Alwahibi Yaser Hassan Dewir Dina A. Soliman Humaira Rizwana This paper describes the preparation, characterization, and evaluation of honey/tripolyphosphate (TPP)/chitosan (HTCs) nanofibers...
Sat Oct 17, 2020 03:00
Molecules, Vol. 25, Pages 4769: Mechanism of Type IA Topoisomerases Molecules doi: 10.3390/molecules25204769 Authors: Tumpa Dasgupta Shomita Ferdous Yuk-Ching Tse-Dinh Topoisomerases in the type IA subfamily can catalyze change in topology for both DNA and RNA substrates. A type IA topoisomerase may have been present in a last universal common ancestor (LUCA) with an RNA genome. Type IA topoisomerases have since evolved to catalyze the resolution of topological barriers encountered...
Sat Oct 17, 2020 03:00
Molecules, Vol. 25, Pages 4768: On a Magical Mystery Tour with 8-Bromo-Cyclic ADP-Ribose: From All-or-None Block to Nanojunctions and the Cell-Wide Web Molecules doi: 10.3390/molecules25204768 Authors: A. Mark Evans A plethora of cellular functions are controlled by calcium signals, that are greatly coordinated by calcium release from intracellular stores, the principal component of which is the sarco/endooplasmic reticulum (S/ER). In 1997 it was generally accepted that activation of...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4766: Copper-Catalyzed Trifluoromethylation of Alkoxypyridine Derivatives Molecules doi: 10.3390/molecules25204766 Authors: Nandor Gyorfi Emese Farkas Norbert Nemet Csaba Weber Zoltan Novak Andras Kotschy The trifluoromethylation of aromatic and heteroaromatic cores has attracted considerable interest in recent years due to its pharmacological relevance. We studied the extension of a simple copper-catalyzed trifluoromethylation protocol to alkoxy-substituted...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4765: Reduction and Oxidation of Cu Species in Cu-Faujasites Studied by IR Spectroscopy Molecules doi: 10.3390/molecules25204765 Authors: Łukasz Kuterasiński Jerzy Podobiński Ewa Madej Małgorzata Smoliło-Utrata Dorota Rutkowska-Zbik Jerzy Datka The process of reduction (by hydrogen and ethanol) and oxidation (by oxygen and NO) of Cu sites in dealuminated faujasite-type zeolites (of Si/Al = 31) was studied by infrared (IR) spectroscopy with CO...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4767: Predicted Reversal in N-Methylazepine/N-Methyl-7-azanorcaradiene Equilibrium Upon Formation of Their N-Oxides Molecules doi: 10.3390/molecules25204767 Authors: René Fournier Alexa R. Green Arthur Greenberg Edward Lee-Ruff Joel F. Liebman Anita Rágyanszki Density functional calculations and up to five different basis sets have been applied to the exploration of the structural, enthalpy and free energy changes upon conversion of the azepine...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4764: Antibody–Drug Conjugates for Cancer Therapy Molecules doi: 10.3390/molecules25204764 Authors: Umbreen Hafeez Sagun Parakh Hui K Gan Andrew M Scott Antibody–drug conjugates (ADCs) are novel drugs that exploit the specificity of a monoclonal antibody (mAb) to reach target antigens expressed on cancer cells for the delivery of a potent cytotoxic payload. ADCs provide a unique opportunity to deliver drugs to tumor cells while minimizing...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4763: Phytochemical Evaluation of Tinctures and Essential Oil Obtained from Satureja montana Herb Molecules doi: 10.3390/molecules25204763 Authors: Nataliia Hudz Ewa Makowicz Mariia Shanaida Marietta Białoń Izabela Jasicka-Misiak Oksana Yezerska Liudmyla Svydenko Piotr Paweł Wieczorek Winter Savory (Satureja montana L.) has been used in traditional medicine and as a spice or natural food preservative in the Mediterranean region for centuries....
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4761: Unravelling the Antifungal Effect of Red Thyme Oil (Thymus vulgaris L.) Compounds in Vapor Phase Molecules doi: 10.3390/molecules25204761 Authors: Loris Pinto Maria Addolorata Bonifacio Elvira De Giglio Stefania Cometa Antonio F. Logrieco Federico Baruzzi The aim of this work was to evaluate the antifungal activity in vapor phase of thymol, p-cymene, and γ-terpinene, the red thyme essential oil compounds (RTOCs). The Minimum Inhibitory...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4762: Bioactive Flavonoid Glycosides and HPLC and UPLC Quantification of Commercial Astragali Complanati Semen Molecules doi: 10.3390/molecules25204762 Authors: Jenny Chun-Ling Kuo Li-Jie Zhang Hung-Tse Huang Chia-Ching Liaw Zhi-Hu Lin Min Liu Yao-Haur Kuo Eleven compounds, including nine known flavonoid glycosides (1–4, 6–8, and 10–11), one isoflavone glycoside (5), and a glansreginic acid (9), were isolated from...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4759: Rhizopus oligosporus and Lactobacillus plantarum Co-Fermentation as a Tool for Increasing the Antioxidant Potential of Grass Pea and Flaxseed Oil-Cake Tempe Molecules doi: 10.3390/molecules25204759 Authors: Bożena Stodolak Anna Starzyńska-Janiszewska Magdalena Mika Agnieszka Wikiera Tempe-type fermentation originating from Indonesia can enhance the antioxidant activity of plant material. However, this biological potential depends on substrates...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4758: Understanding the Factors Influencing Chitosan-Based Nanoparticles-Protein Corona Interaction and Drug Delivery Applications Molecules doi: 10.3390/molecules25204758 Authors: Cristina Moraru Manuela Mincea Gheorghita Menghiu Vasile Ostafe Chitosan is a polymer that is extensively used to prepare nanoparticles (NPs) with tailored properties for applications in many fields of human activities. Among them, targeted drug delivery, especially when...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4757: Potential Beneficial Effects of Extra Virgin Olive Oils Characterized by High Content in Minor Polar Compounds in Nephropathic Patients: A Pilot Study Molecules doi: 10.3390/molecules25204757 Authors: Annalisa Romani Roberta Bernini Annalisa Noce Silvia Urciuoli Manuela Di Lauro Anna Pietroboni Zaitseva Giulia Marrone Nicola Di Daniele Extra virgin olive oil (EVOO) is a lipid food, which constitutes a pillar of the Mediterranean diet....
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4756: Influence of Nanoencapsulation Using High-Pressure Homogenization on the Volatile Constituents and Anticancer and Antioxidant Activities of Algerian Saccocalyx satureioides Coss. et Durieu Molecules doi: 10.3390/molecules25204756 Authors: Abdelhakim Aouf Hatem Ali Abdel Rahman Al-Khalifa Khaled Fahmy Mahmoud Amr Farouk The nanoencapsulation of essential oils enhances their applicability in several areas, such as pharmaceuticals and food biopreservation....
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4755: Anti-Melanogenic Effects of Korean Red Ginseng Oil in an Ultraviolet B-Induced Hairless Mouse Model Molecules doi: 10.3390/molecules25204755 Authors: Evelyn Saba Seung-Hyung Kim Yuan Yee Lee Hyun-Kyoung Kim Seong-Soo Roh Yi-Seong Kwak Chae-Kyu Park Sung-Dae Kim Man Hee Rhee A ‘remedy for all’ natural product widely known in the Korean Peninsula is called Panax Ginseng Meyer. Globalization represents a persistent...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4760: Involvement of miR-142 and miR-155 in Non-Infectious Complications of CVID Molecules doi: 10.3390/molecules25204760 Authors: Giuliana Amato Federica Vita Paolina Quattrocchi Paola Lucia Minciullo Giovanni Pioggia Sebastiano Gangemi Background and objectives: Common variable immunodeficiency (CVID) is the most prevalent antibody impairment. It is characterized by failure in immunoglobulin and protective antibody generation and defined by...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4754: Raman Spectroscopy Studies on the Barocaloric Hybrid Perovskite [(CH3)4N][Cd(N3)3] Molecules doi: 10.3390/molecules25204754 Authors: Rosivaldo Xavier da Silva Carlos William de Araujo Paschoal Clenilton Costa dos Santos Alberto García-Fernández Jorge Salgado-Beceiro María Antonia Señarís-Rodríguez Manuel Sanchez-Andujar Ariel Nonato Almeida de Abreu Silva Temperature-dependent Raman scattering and differential scanning calorimetry...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4751: Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors Molecules doi: 10.3390/molecules25204751 Authors: Baole Zhang Luping Pang Manesh Nautiyal Steff De Graef Bharat Gadakh Eveline Lescrinier Jef Rozenski Sergei V. Strelkov Stephen D. Weeks Arthur Van Aerschot Aminoacyl-tRNA synthetases (aaRSs) have become viable targets...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4753: Gut/Oral Bacteria Variability May Explain the High Efficacy of Green Tea in Rodent Tumor Inhibition and Its Absence in Humans Molecules doi: 10.3390/molecules25204753 Authors: Guy R. Adami Christy Tangney Joel L. Schwartz Kim Chi Dang Consumption of green tea (GT) and GT polyphenols has prevented a range of cancers in rodents but has had mixed results in humans. Human subjects who drank GT for weeks showed changes in oral microbiome. However,...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4752: Chitosan Hydrochloride Decreases Fusarium graminearum Growth and Virulence and Boosts Growth, Development and Systemic Acquired Resistance in Two Durum Wheat Genotypes Molecules doi: 10.3390/molecules25204752 Authors: Francesconi Steiner Buerstmayr Lemmens Sulyok Balestra Fusarium head blight (FHB) is a devastating disease for cereals. FHB is managed by fungicides at anthesis, but their efficacy is variable. Conventional fungicides...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4750: Numerical Simulations as Means for Tailoring Electrically Conductive Hydrogels Towards Cartilage Tissue Engineering by Electrical Stimulation Molecules doi: 10.3390/molecules25204750 Authors: Julius Zimmermann Thomas Distler Aldo R. Boccaccini Ursula van van Rienen Cartilage regeneration is a clinical challenge. In recent years, hydrogels have emerged as implantable scaffolds in cartilage tissue engineering. Similarly, electrical stimulation...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4749: A Review of Molecular Imaging of Glutamate Receptors Molecules doi: 10.3390/molecules25204749 Authors: Jong-Hoon Kim János Marton Simon Mensah Ametamey Paul Cumming Molecular imaging with positron emission tomography (PET) and single photon emission computed tomography (SPECT) is a well-established and important in vivo technique to evaluate fundamental biological processes and unravel the role of neurotransmitter receptors in various neuropsychiatric...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4745: Molecular Dynamic Simulations to Probe Stereoselectivity of Tiagabine Binding with Human GAT1 Molecules doi: 10.3390/molecules25204745 Authors: Sadia Zafar Ishrat Jabeen The human gamma aminobutyric acid transporter subtype 1 (hGAT1) located in the nerve terminals is known to catalyze the neuronal function by the electrogenic reuptake of γ-aminobutyric acid (GABA) with the co-transport of Na+ and Cl− ions. In the past, there has...
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4747: Global Dental Publications in PubMed Databases between 2009 and 2019—A Bibliometric Analysis Molecules doi: 10.3390/molecules25204747 Authors: Faris Yahya Asiri Estie Kruger Marc Tennant The objective of this study was to evaluate the publications in the field of dentistry on the PubMed database over a span of 10 years, from 2009 to 2019. Articles published between January 2009 to December 2019 were searched for in the MEDLINE database via PubMed....
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4748: Neurite Outgrowth-Promoting Activity of Compounds in PC12 Cells from Sunflower Seeds Molecules doi: 10.3390/molecules25204748 Authors: Takeru Koga Takaiku Sakamoto Eiji Sakuradani Akihiro Tai In the current super-aging society, the establishment of methods for prevention and treatment of Alzheimer’s disease (AD) is an urgent task. One of the causes of AD is thought to be a decrease in the revel of nerve growth factor (NGF) in the brain....
Fri Oct 16, 2020 03:00
Molecules, Vol. 25, Pages 4746: Special Issue “Flavonoids and Their Disease Prevention and Treatment Potential”: Recent Advances and Future Perspectives Molecules doi: 10.3390/molecules25204746 Authors: H.P. Vasantha Rupasinghe In recent years, the interest in flavonoids as dietary bioactives to prevent human diseases, as well as their candidacy as pharmaceutical leads, has exponentially expanded [...]
Fri Oct 16, 2020 03:00
MTI, Vol. 4, Pages 74: Self-Perception and Training Perceptions on Teacher Digital Competence (TDC) in Spanish and French University Students Multimodal Technologies and Interaction doi: 10.3390/mti4040074 Authors: Delfín Ortega-Sánchez Isabel María Gómez-Trigueros Marc Trestini Carlos Pérez-González The purpose of this research is, on the one hand, to analyze the self-perception of future teachers of childhood education and primary education, and those studying for a master’s...
Sat Oct 17, 2020 03:00
MTI, Vol. 4, Pages 73: Multimodal Navigation Systems for Users with Visual Impairments—A Review and Analysis Multimodal Technologies and Interaction doi: 10.3390/mti4040073 Authors: Bineeth Kuriakose Raju Shrestha Frode Eika Sandnes Multimodal interaction refers to situations where users are provided with multiple modes for interacting with systems. Researchers are working on multimodality solutions in several domains. The focus of this paper is within the domain of navigation...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2057: Tunable Microwave Filters Using HfO2-Based Ferroelectrics Nanomaterials doi: 10.3390/nano10102057 Authors: Martino Aldrigo Mircea Dragoman Sergiu Iordanescu Florin Nastase Silviu Vulpe In this paper, we present microwave filters that are based on 6-nm-thick ferroelectric thin films of hafnium oxide doped with zirconium (HfZrO), which are tunable continuously in targeted bands of interest within the frequency range 0.1–16 GHz,...
Sun Oct 18, 2020 03:00
Nanomaterials, Vol. 10, Pages 2056: The Mechanical Effect of MnO2 Layers on Electrochemical Actuation Performance of Nanoporous Gold Nanomaterials doi: 10.3390/nano10102056 Authors: Zhifei Han Zhengpan Qi Qiang Wei Qibo Deng Ke Wang This study investigated the electrochemical actuation behavior of nanoporous material during the capacitive process. The length change of nanoporous gold (npg) was in situ investigated in a liquid environment using the dilatometry technique. The...
Sun Oct 18, 2020 03:00
Nanomaterials, Vol. 10, Pages 2055: Synaptic Characteristics from Homogeneous Resistive Switching in Pt/Al2O3/TiN Stack Nanomaterials doi: 10.3390/nano10102055 Authors: Hojeong Ryu Sungjun Kim In this work, we propose three types of resistive switching behaviors by controlling operation conditions. We confirmed well-known filamentary switching in Al2O3-based resistive switching memory using the conventional device working operation with a forming process. Here, filamentary switching...
Sun Oct 18, 2020 03:00
Nanomaterials, Vol. 10, Pages 2054: In Situ Ultraviolet Polymerization Using Upconversion Nanoparticles: Nanocomposite Structures Patterned by Near Infrared Light Nanomaterials doi: 10.3390/nano10102054 Authors: Hongsub Jee Guanying Chen Paras N. Prasad Tymish Y. Ohulchanskyy Jaehyeong Lee In this paper, we report an approach to polymerization of a nanocomposite containing UV-polymerizable organic material and inorganic, NaYbF4:Tm3+ core-based nanoparticles (NPs), which are...
Sat Oct 17, 2020 03:00
Nanomaterials, Vol. 10, Pages 2053: Synthesis of Mo2C by Thermal Decomposition of Molybdenum Blue Nanoparticles Nanomaterials doi: 10.3390/nano10102053 Authors: Natalia Gavrilova Victor Dyakonov Maria Myachina Victor Nazarov Valery Skudin In recent years, the development of methods for the synthesis of Mo2C for catalytic application has become especially important. In this work a series of Mo2C samples was synthesized by thermal decomposition of molybdenum blue xerogels obtained...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2050: Graphene Flakes for Electronic Applications: DC Plasma Jet-Assisted Synthesis Nanomaterials doi: 10.3390/nano10102050 Authors: Irina V. Antonova Marina B. Shavelkina Artem I. Ivanov Regina A. Soots Peter P. Ivanov Alexey N. Bocharov The possibility of graphene synthesis (the bottom-up approach) in plasma and the effective control of the morphology and electrical properties of graphene-based layers were demonstrated. Graphene flakes were...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2052: Towards the Continuous Hydrothermal Synthesis of ZnO@Mg2Al-CO3 Core-Shell Composite Nanomaterials Nanomaterials doi: 10.3390/nano10102052 Authors: Ian Clark Jacob Smith Rachel L. Gomes Edward Lester Core-shell Zinc Oxide/Layered Double Hydroxide (ZnO@LDH) composite nanomaterials have been produced by a one-step continuous hydrothermal synthesis process, in an attempt to further enhance the application potential of layered double hydroxide...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2048: Ecotoxicity Assessment of Graphene Oxide by Daphnia magna through a Multimarker Approach from the Molecular to the Physiological Level including Behavioral Changes Nanomaterials doi: 10.3390/nano10102048 Authors: Ildikó Fekete-Kertész Krisztina László Csilla Terebesi Benjámin Sándor Gyarmati Shereen Farah Rita Márton Mónika Molnár The extensive use of engineered nanomaterials, such as graphene oxide (GO), is stimulating research about...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2051: Dual Stimuli-Responsive Copper Nanoparticles Decorated SBA-15: A Highly Efficient Catalyst for the Oxidation of Alcohols in Water Nanomaterials doi: 10.3390/nano10102051 Authors: Thomas Peter Nagappan Mohan Ha In the present work, a temperature and pH-responsive hybrid catalytic system using copolymer-capped mesoporous silica particles with metal nanoparticles is proposed. The poly(2-(dimethylamino)ethyl methacrylate)(DMAEMA)-co-N-tert-butyl...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2049: Ultra-High Energy Density Hybrid Supercapacitors Using MnO2/Reduced Graphene Oxide Hybrid Nanoscrolls Nanomaterials doi: 10.3390/nano10102049 Authors: Rani Thangavel Kim Lee Jang Manganese oxide (MnO2) is a promising material for supercapacitor applications, with a theoretical ultra-high energy density of 308 Wh/kg. However, such ultra-high energy density has not been achieved experimentally in MnO2-based supercapacitors because of...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2047: Bottom-Up Self-Assembly Based on DNA Nanotechnology Nanomaterials doi: 10.3390/nano10102047 Authors: Yan Huang Wang Tang Tian Manipulating materials at the atomic scale is one of the goals of the development of chemistry and materials science, as it provides the possibility to customize material properties; however, it still remains a huge challenge. Using DNA self-assembly, materials can be controlled at the nano scale to achieve...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2046: Current Research of Graphene-Based Nanocomposites and Their Application for Supercapacitors Nanomaterials doi: 10.3390/nano10102046 Authors: Santosh K. Tiwari Anukul K. Thakur Amrita De Adhikari Yanqiu Zhu Nannan Wang This review acmes the latest developments of composites of metal oxides/sulfide comprising of graphene and its analogues as electrode materials in the construction of the next generation of supercapacitors (SCs). SCs have...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2045: 2D CTAB-MoSe2 Nanosheets and 0D MoSe2 Quantum Dots: Facile Top-Down Preparations and Their Peroxidase-Like Catalytic Activity for Colorimetric Detection of Hydrogen Peroxide Nanomaterials doi: 10.3390/nano10102045 Authors: Da-Ren Hang Ya-Qi Pan Krishna Hari Sharma Mitch M. C. Chou Sk Emdadul Islam Hui-Fen Wu Chi-Te Liang We report the facile and economic preparation of two-dimensional (2D) and 0D MoSe2 nanostructures based on systematic...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2043: The Thermoelectric Properties of Monolayer MAs2 (M = Ni, Pd and Pt) from First-Principles Calculations Nanomaterials doi: 10.3390/nano10102043 Authors: Qiang-Lin Wei Heng-Yu Yang Yi-Yuan Wu Yi-Bao Liu Yu-Hong Li The thermoelectric property of the monolayer MAs2 (M = Ni, Pd and Pt) is predicted based on first principles calculations, while combining with the Boltzmann transport theory to confirm the influence of phonon and electricity transport...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2042: Transport Properties of Electro-Sprayed Polytetrafluoroethylene Fibrous Layer Filled with Aerogels/Phase Change Materials Nanomaterials doi: 10.3390/nano10102042 Authors: Xiaoman Xiong Mohanapriya Venkataraman Tao Yang Klara Kucerova Jiří Militký Kai Yang Guocheng Zhu Juming Yao This work is the first attempt to prepare microporous polytetrafluoroethylene (PTFE) fibrous layers embedded with aerogels/phase change materials. For...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2044: A Sensitive FRET Biosensor Based on Carbon Dots-Modified Nanoporous Membrane for 8-hydroxy-2′-Deoxyguanosine (8-OHdG) Detection with Au@ZIF-8 Nanoparticles as Signal Quenchers Nanomaterials doi: 10.3390/nano10102044 Authors: Weiwei Ye Yu Zhang Wei Hu Liwen Wang Yu Zhang Ping Wang A sensitive fluorescence resonance energy transfer (FRET) biosensor is proposed to detect 8-hydroxy-2′-deoxyguanosine (8-OHdG), which is a typical...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2041: Nanocellulose Bio-Based Composites for Food Packaging Nanomaterials doi: 10.3390/nano10102041 Authors: Francisco A. G. S. Silva Fernando Dourado Miguel Gama Fátima Poças The food industry is increasingly demanding advanced and eco-friendly sustainable packaging materials with improved physical, mechanical and barrier properties. The currently used materials are synthetic and non-degradable, therefore raising environmental concerns. Consequently,...
Fri Oct 16, 2020 03:00
Nanomaterials, Vol. 10, Pages 2040: Ultrastructural Features of Gold Nanoparticles Interaction with HepG2 and HEK293 Cells in Monolayer and Spheroids Nanomaterials doi: 10.3390/nano10102040 Authors: Boris Chelobanov Julia Poletaeva Anna Epanchintseva Anastasiya Tupitsyna Inna Pyshnaya Elena Ryabchikova Use of multicellular spheroids in studies of nanoparticles (NPs) has increased in the last decade, however details of NPs interaction with spheroids are poorly known. We...
Fri Oct 16, 2020 03:00
Nutrients, Vol. 12, Pages 3186: The Beneficial Effect of Boswellic Acid on Bone Metabolism and Possible Mechanisms of Action in Experimental Osteoporosis Nutrients doi: 10.3390/nu12103186 Authors: Bandar E. Al-Dhubiab Snehal S. Patel Mohamed A. Morsy Harika Duvva Anroop B. Nair Pran Kishore Deb Jigar Shah Estrogen is instrumental in the pathological process of osteoporosis because a deficiency of this hormone increases the release of bone-resorbing cytokines. Acetyl-11-keto-β-boswellic...
Sun Oct 18, 2020 03:00
Nutrients, Vol. 12, Pages 3184: Diet to Reduce the Metabolic Syndrome Associated with Menopause. The Logic for Olive Oil Nutrients doi: 10.3390/nu12103184 Authors: Juan José Hidalgo-Mora Laura Cortés-Sierra Miguel-Ángel García-Pérez Juan J. Tarín Antonio Cano The rates of metabolic syndrome are increasing in parallel with the increasing prevalence of obesity, primarily due to its concomitant insulin resistance. This is particularly concerning for women, as the years around...
Sun Oct 18, 2020 03:00
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