Margins are employed in radiotherapy treatment planning to mitigate the dosimetric effects of geometric uncertainties for the clinical target volume (CTV). Here, we proposed a margin concept that takes into co...
Sat Oct 17, 2020 03:00
Methods for the non-invasive quantification of changes in bladder wall thickness as potential predictors of radiation cystitis in pre-clinical research would be desirable. The use of ultrasound for this aim se...
Sat Oct 17, 2020 03:00
To evaluate inter-fractional variations in bladder and rectum during prostate stereotactic body radiation therapy (SBRT) and determine dosimetric and clinical consequences.
Fri Oct 16, 2020 03:00
The object of the research is the painting, Portrait of a Musician’’. Upon closer examination of the painting, we discovered three details. Two have the shape of trachea and bronchi and the third a larynx. By moving the details through the program Paint X we got an image of the larynx, trachea and bronchi. The larynx is presented by thyroid and cricoid cartilage. The characteristic cartilaginous rings are distinguished on the trachea. The right and left main bronchi are also seen. In our opinion,...
Sat Oct 17, 2020 03:00
To determine the laryngoscopic findings most predictive of laterality in vocal fold paresis in patients with known RLN and/or SLN paresis by laryngeal electromyography (LEMG).
Sat Oct 17, 2020 03:00
Some classically trained singers demonstrate great performance longevity. These singers continue to produce a professionally viable voice that belies their age. This study was designed to assess selected acoustic characteristics of 10 currently performing classical singers from 2 recordings; one early, and one recent. The mean age at the early and recent recording was 39 and 64, respectively, with a mean of 25 years between recordings. Vibrato rate, extent, and consistency were calculated. The singers...
Fri Oct 16, 2020 03:00
Deep brain stimulation (DBS) is a treatment for medically refractory essential tremor (ET), but there is a paucity of literature examining the effects of DBS on voice in patients with ET pre-DBS and post-DBS. This study aimed to report a comprehensive evaluation of voice in patients with ET pre-DBS and 6-months post-DBS.
Fri Oct 16, 2020 03:00
During COVID-19, government measures to prevent disease spread included advice to work from home. In addition to occupational risk factors, the increased use of telecommunication and changed work environment may contribute to voice and vocal tract discomfort (VTD). This study established the prevalence, incidence, characteristics and impact of self-perceived dysphonia and VTD in those working from home during COVID-19.
Fri Oct 16, 2020 03:00
Degenerative changes of the temporomandibular joint (TMJ) present with a broad spectrum of morphological alterations. However, erosions leading to a glenoid fossa defect and condylar impingement of the temporal lobe are a rare finding. A 77-year-old female patient presented with limited mouth opening and pre-auricular pain during mastication on the left side. She denied any neurological dysfunction. Her medical history included poliomyelitis, multiple cancers, and osteonecrosis of the left tibial...
Sat Oct 17, 2020 03:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07128
Fri Oct 16, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07791
Fri Oct 16, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c10015
Fri Oct 16, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07251
Fri Oct 16, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c08231
Fri Oct 16, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c09220
Fri Oct 16, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c10406
Fri Oct 16, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c09080
Fri Oct 16, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c08886
Fri Oct 16, 2020 07:00
[ASAP] Ratiometric Turn-On Fluorophore Displacement Ensembles for Nitroaromatic Explosives Detection
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c08106
Fri Oct 16, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07224
Thu Oct 15, 2020 07:00
The eighth edition of the Union for International Cancer Control (UICC) staging manual was recently introduced. The staging of oral cavity squamous cell carcinoma saw changes in relation to depth of invasion and extra-nodal extension. We aimed to evaluate this system and its prognostic ability in a UK cohort. A retrospective review was undertaken of patients diagnosed with squamous cell carcinoma (SCC) of the oral cavity between January 2009 and December 2013. Data were collected on demographics,...
Sat Oct 17, 2020 03:00
This study was undertaken with the aim to compare the T stages in a series of cutaneous squamous cell carcinoma (cSCC) patients using both the eighth edition of the Union for International Cancer Control (UICC) TNM Classification of Malignant Tumours (TNM8) and Brigham and Women’s Hospital (BWH) staging systems. This would allow comparison of the two to determine suitability with regards to T stage and the effect on local recurrence and nodal disease. This was a six-year retrospective cohort study...
Fri Oct 16, 2020 03:00
A 13-year boy presented to our tertiary care hospital with a history of progressive nasal obstruction and epistaxis. On further evaluation, he was found to have juvenile nasopharyngeal angiofibroma (JNA) extending into the infratemporal fossa (ITF) and adjacent soft tissue of the cheek. He was managed surgically by a maxillary swing approach. The purpose of this letter is to revisit one of the classic, but rarely appreciated, radiological signs that we encountered in this patient.
Fri Oct 16, 2020 03:00
I commend the recent Editorial by Brennan and colleagues in allegiance with the Black Lives Matter movement towards ensuring global health equity. I wish to elaborate on the authors’ candid remark, “racism remains a public health emergency”, by highlighting the inequalities that disproportionately affect Black, Asian and minority ethnic people presenting with oral cancer and encourage advocacy for tackling socio-economic inequalities rooted in ethnicity and race as a priority for the oncological...
Fri Oct 16, 2020 03:00
Mon Oct 05, 2020 11:17
Mon Oct 05, 2020 11:17
Mon Oct 05, 2020 11:17
Abstract Objective Whether oral health care during the perioperative period can lead to a better outcome after heart valve surgery has not been adequately elucidated. We examined the effects of perioperative oral care on postoperative inflammation response in patients who underwent heart valve surgery. Materials and Methods In this retrospective cohort study, 223 patients scheduled for single valve heart surgery were divided into the oral care, who underwent professional teeth cleaning...
Sat Oct 17, 2020 11:34
Abstract Objectives To provide a comprehensive qualitative and quantitative assessment of any potential differences in melatonin levels in periodontitis versus the healthy state. Materials and Methods The keyword combination “melatonin” AND “periodontitis” was searched in Web of Science, PubMed, and Scopus. Qualitative and quantitative analysis was performed on articles satisfying the inclusion criteria. Results Only 14 studies were included in the systematic review, out of which...
Thu Oct 15, 2020 20:34
Abstract Background Phototherapy with narrow‐band Ultraviolet B (nb‐UVB) is a major therapeutic option in atopic dermatitis (AD), yet knowledge of the early molecular responses to this treatment is lacking. Objective To map the early transcriptional changes in AD skin in response to nb‐UVB treatment. Methods Adult patients (n = 16) with AD were included in the study and scored with validated scoring tools. AD skin was irradiated with local nb‐UVB on day 0, 2 and 4. Skin biopsies were...
Sat Oct 17, 2020 22:12
Abstract Damage‐associated molecular patterns (DAMPs) have drawn much attention as a member of disease‐associated molecules in systemic sclerosis (SSc). In this study we investigated the potential contribution of S100A12, a member of DAMPs, to the development of SSc by evaluating S100A12 expression in the lesional skin and the clinical correlation of serum S100A12 levels. S100A12 expression was markedly elevated in the epidermis of SSc involved skin at protein levels and in the bulk skin at mRNA...
Sat Oct 17, 2020 17:09
Abstract Food allergy is an antigen‐specific immunological adverse reaction after exposure to a given food. Multiple clinical studies showed that oral immunotherapy (OIT) is effective for the prevention and treatment for food allergy that is developed in infants and children. However, the effectiveness of OIT for epicutaneously sensitized food allergy remains unclear. Previously, we established a mouse model of epicutaneous‐sensitized food allergy. In this model, systemic allergic reaction including...
Fri Oct 16, 2020 15:20
Authors: Namwiinga Rozaria Mulunda, Kyoko Hayashida, Junya Yamagishi, Sandie Sianongo, Gilbert Munsaka, Chihiro Sugimoto and Mable Mwale Mutengo.Parasite Vol. 27 , page 53Published online: 13/10/2020 Keywords: Cryptosporidium ; Diarrhoeal disease ; Zambia ; Subtype ; Zoonosis.
Tue Oct 13, 2020 03:00
Publication date: Available online 17 October 2020Source: Behavioural Brain ResearchAuthor(s): Zhi-yuan Wang, Liang-kun Guo, Xiao Han, Rui Song, Guo-ming Dong, Chun-ming Ma, Ning Wu, Jin Li
Sat Oct 17, 2020 21:55
Publication date: Available online 16 October 2020Source: Behavioural Brain ResearchAuthor(s): Sara Sabihi, Caitlin Goodpaster, Skyler Maurer, Benedetta Leuner
Sat Oct 17, 2020 21:55
Publication date: Available online 16 October 2020Source: Behavioural Brain ResearchAuthor(s): Xiaoqin Tan, Zhibin Liang, Yingui Li, Yingkun Zhi, Lang Yi, Shasha Bai, Kelly H. Forest, Robert A. Nichols, Yan Dong, Qing X Li
Fri Oct 16, 2020 19:53
Publication date: Available online 16 October 2020Source: Behavioural Brain ResearchAuthor(s): Sara Pereira Braga, Eslen Delanogare, Adriano Emanuel Machado, Rui Daniel Prediger, Eduardo Luiz Gasnhar Moreira
Fri Oct 16, 2020 19:53
Publication date: Available online 15 October 2020Source: Behavioural Brain ResearchAuthor(s): Hilary A. Marusak, Aneesh Hehr, Amanpreet Bhogal, Craig Peters, Allesandra Iadipaolo, Christine A. Rabinak
Fri Oct 16, 2020 19:53
Publication date: Available online 17 October 2020Source: Revista de Logopedia, Foniatría y AudiologíaAuthor(s): Silvia Nieva, Eva Aguilar-Mediavilla, Lidia Rodríguez, Barbara T. Conboy
Sat Oct 17, 2020 20:18
The only way out of today’s misery is for people to become worthy of each other’s trust.— Albert Schweitzer As the race to develop a vaccine for Covid-19 has reached phase 3 clinical trials, concerns are increasing about the low rates of trial participation in important subgroups, including Black…
Fri Oct 16, 2020 03:00
Publication date: Available online 17 October 2020Source: Journal of VoiceAuthor(s): Grigol Keshelava
Sat Oct 17, 2020 20:00
Publication date: Available online 17 October 2020Source: Journal of VoiceAuthor(s): Monica A. McHenry, Joseph Evans
Sat Oct 17, 2020 20:00
Publication date: Available online 17 October 2020Source: Journal of VoiceAuthor(s): Sungjin A. Song, Alena Santeerapharp, Ghiath Alnouri, Jin Park, Robert T. Sataloff, Ramon A. Franco
Sat Oct 17, 2020 20:00
Publication date: Available online 16 October 2020Source: Journal of VoiceAuthor(s): Ciarán Kenny
Sat Oct 17, 2020 20:00
Publication date: Available online 16 October 2020Source: Journal of VoiceAuthor(s): Kathryn W. Ruckart, Mary E. Moya-Mendez, Moeko Nagatsuka, Julia L. Barry, Mustafa S. Siddiqui, Lyndsay L. Madden
Fri Oct 16, 2020 16:10
Publication date: Available online 16 October 2020Source: Journal of VoiceAuthor(s): Lisa Fornhammar, Johan Sundberg, Michael Fuchs, Lennart Pieper
Fri Oct 16, 2020 16:10
Publication date: Available online 16 October 2020Source: Journal of VoiceAuthor(s): Jin-an Wang, Xinlin Xu, Yanli Ma, Peiyun Zhuang, Yong Wang
Fri Oct 16, 2020 16:10
Objectives/Hypothesis We have seen several incidences of catastrophic bleeding in patients with advanced oropharyngeal squamous cell carcinoma treated nonoperatively. Aside from advanced disease, these patients have not had traditional risk factors for major hemorrhage. Study Design Retrospective chart review. Methods Patients treated nonoperatively for oropharyngeal squamous cell carcinoma were compared to determine characteristics that may predisposed to bleeding. Five patients with...
Sat Oct 17, 2020 15:56
Objective Most acellular injectable biomaterials for vocal fold (VF) wound treatment have limited regenerative potential due to their fast enzymatic degradation and limited recruitment of native cells postinjection. The injection of cells as therapeutic treatment often results in apoptosis due to stresses within the needle and the immune response of the host. Degradable microspheres may improve treatment effectiveness by increasing cell residence time, shielding cells during injection, and offering...
Sat Oct 17, 2020 15:50
Abstract Objective The objective of this meta‐analysis was to look at the pooled prevalence of symptoms, Laboratory tests and imaging of all COVID‐19 infected patients. This will allow better identification of potential COVID‐19 patients and take appropriate precautions. Methods We searched three databases, PubMed, EMBASE and Ovid to identify studies published between Dec‐2019 and May‐2020. All studies reporting upper‐aerodigestive symptoms of COVID‐19 infection were included. The meta‐analysis...
Sat Oct 17, 2020 12:28
Publication date: January 2021Source: Clinical Imaging, Volume 69Author(s): Siddharth Thaker, Ghassan Almeer, Jonathan Stevenson, Christine Azzopardi, Rajesh Botchu
Sat Oct 17, 2020 18:23
Hypochondrogenesis: A pictorial assay combining ultrasound, MRI and low-dose computerized tomography
Publication date: January 2021Source: Clinical Imaging, Volume 69Author(s): Roy U. Bisht, Mohan V. Belthur, Ian M. Singleton, Julia E. Solomon, Luis F. Goncalves
Fri Oct 16, 2020 17:18
Publication date: January 2021Source: Clinical Imaging, Volume 69Author(s): Yonah B. Esterson, Sheila Sheth, Satomi Kawamoto
Fri Oct 16, 2020 17:18
Abstract Background Quantitative mapping of MRI relaxation times is expected to uncover pathological processes in the brain more subtly than standard MRI techniques with weighted contrasts. So far, however, most mapping techniques suffer from a long measuring time, low spatial resolution or even sensitivity to magnetic field inhomogeneity. Objective ...
Sat Oct 17, 2020 03:00
Publication date: Available online 16 October 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): Jay Patel
Sat Oct 17, 2020 17:46
Abstract Malignant cells can increase in number using immune escape mechanisms such as immune checkpoints. In this study, we evaluated the expression of an immune checkpoint programmed death 1 (PD-1) on T-cell subsets in chronic myeloid leukemia (CML). We obtained bone marrow aspirate samples from CML patients and from individuals without evidence of hematologic malignancies (controls). PD-1 expression on T-cell subsets was measured using flow cytometric analysis. PD-1 expression...
Sat Oct 17, 2020 17:44
Abstract Controlling the balance of pro-inflammatory M1 versus anti-inflammatory M2 macrophages may have paramount therapeutic benefit in cardiovascular diseases, infections, cancer and chronic inflammation. The targeted depletion of different macrophage populations provides a therapeutic option to regulate macrophage-mediated functions. Macrophages are highly sensitive to necroptosis, a newly described regulated cell death mediated by receptor-interacting serine/threonine-protein...
Sat Oct 17, 2020 17:44
Abstract T-cell receptor (TCR)- and chimeric antigen receptor (CAR)-based adoptive cell transfer (ACT) has shown promising results in hematological malignancies, but remains immature in solid cancers. The challenges associated with identification of tumor-specific targets, the heterogenic antigen expression, limited T-cell trafficking to tumor sites and the hostile tumor microenvironment (TME), are all factors contributing to the limited efficacy of ACT therapies against solid...
Sat Oct 17, 2020 17:44
Abstract Tumor-specific tumor-infiltrating lymphocytes (TILs) can be in vitro expanded and have the ability to induce complete and durable tumor regression in some patients with melanoma following adoptive cell therapy (ACT). In this preclinical study, we investigated the feasibility of expanding TIL from sarcomas, as well as performing functional in vitro analyses on these. TILs were expanded in vitro by the use of IL2 stimulation with or without the addition of 4-1BB and CD3...
Sat Oct 17, 2020 17:44
Abstract Background Checkpoint inhibitor pneumonitis (CIP) is an immune-related adverse event that may complicate treatment with immune checkpoint inhibitors (ICI) and can cause significant morbidity. We sought to identify predictors for the development of CIP, and whether the use of inhaled corticosteroids (ICS) at time of ICI may be protective. Methods ...
Sat Oct 17, 2020 17:44
Abstract Background Single-agent pembrolizumab represents the standard first-line option for metastatic non-small-cell lung cancer (NSCLC) patients with a PD-L1 (programmed death-ligand 1) expression of ≥ 50%. Methods We conducted a multicenter retrospective study aimed at evaluating the clinicopathologic correlates of pembrolizumab effectiveness...
Sat Oct 17, 2020 17:44
Publication date: Available online 17 October 2020Source: Radiotherapy and OncologyAuthor(s): Shun-Ichiro Kageyama, Junyan Du, Syuzo Kaneko, Ryuji Hamamoto, Shigeo Yamaguchi, Riu Yamashita, Masayuki Okumura, Atsushi Motegi, Hidehiro Hojo, Masaki Nakamura, Katsuya Tsuchihara, Tetsuo Akimoto
Sat Oct 17, 2020 17:31
Publication date: Available online 17 October 2020Source: Radiotherapy and OncologyAuthor(s): William H. Smith, Jamie Cesaretti, Chih Peng Chin, Mitchell Terk, Richard G. Stock
Sat Oct 17, 2020 17:31
Publication date: Available online 17 October 2020Source: Radiotherapy and OncologyAuthor(s): Suman Shrestha, Aashish C. Gupta, James E. Bates, Choonsik Lee, Constance A. Owens, Bradford S. Hoppe, Louis S. Constine, Susan A. Smith, Ying Qiao, Rita E. Weathers, Yutaka Yasui, Laurence E. Court, Arnold C. Paulino, Chelsea C. Pinnix, Stephen F. Kry, David S. Followill, Gregory T. Armstrong, Rebecca M. Howell
Sat Oct 17, 2020 17:31
Publication date: Available online 17 October 2020Source: Radiotherapy and OncologyAuthor(s): Matthew G. Parry, Julie Nossiter, Thomas E. Cowling, Arunan Sujenthiran, Brendan Berry, Paul Cathcart, Noel W. Clarke, Heather Payne, Jan van der Meulen, Ajay Aggarwal
Sat Oct 17, 2020 17:31
Publication date: Available online 17 October 2020Source: Radiotherapy and OncologyAuthor(s): Davide Cusumano, Jacopo Lenkowicz, Claudio Votta, Luca Boldrini, Lorenzo Placidi, Francesco Catucci, Nicola Dinapoli, Marco Valerio Antonelli, Angela Romano, Viola De Luca, Giuditta Chiloiro, Luca Indovina, Vincenzo Valentini
Sat Oct 17, 2020 17:31
Publication date: Available online 16 October 2020Source: Radiotherapy and OncologyAuthor(s): Benjamin S. Rosen, Joel R. Wilkie, Yilun Sun, Mohannad Ibrahim, Keith A. Casper, Jessa E. Miller, Thong Chotchutipan, Chaz L. Stucken, Carol Bradford, Mark E. P. Prince, Andrew J. Rosko, Kelly M. Malloy, Scott A. McLean, Steven B. Chinn, Andrew G. Shuman, Matthew E. Spector, Paul L. Swiecicki, Francis P. Worden, Jennifer Shah, Caitlin A. Schonewolf
Fri Oct 16, 2020 16:42
Publication date: December 2020Source: Brain and Language, Volume 211Author(s): Nicola Del Maschio, Simone Sulpizio, Jubin Abutalebi
Sat Oct 17, 2020 17:28
Publication date: December 2020Source: Brain and Language, Volume 211Author(s): Mark Yates, John Shelley-Tremblay, Donald Lee Knapp
Fri Oct 16, 2020 14:28
Abstract This study was conducted in order to compare the safety and efficacy of LLLT, 5% minoxidil, and combination therapy in the treatment of FPHL. A randomized controlled trial was developed to study the effect of LLLT on FPHL using a device called iHelmet®, which is equipped with 200 5mW laser diode source (650 nm) arrays. Ninety Ludwig’s types II–III FPHL patients were randomly divided into 3 groups: LLLT group (A), 5% minoxidil group (B), and combination group(C). Hair...
Sat Oct 17, 2020 03:00
Abstract The evaluation of pigmented lesions on tattooed skin poses a diagnostic challenge for dermatologists, as a nevus may be partially or completely obscured by tattoo pigment. Because of incidences of melanoma arising from tattooed skin, the current gold standard is to biopsy these lesions. Reflectance confocal microscopy (RCM) is a noninvasive imaging modality used in the diagnosis and management of skin diseases that may allow for diagnosis, while preserving the tattoo...
Sat Oct 17, 2020 03:00
Abstract Deep dyspareunia affects almost half of the women with endometriosis and is associated with vaginal endometriotic lesions. Our pilot study’s objective is to assess the feasibility and effectiveness of CO2-laser ablation under colposcopic guidance for the treatment of symptomatic vaginal endometriosis. A non-comparative pilot study has been performed. Only women with histologically proven vaginal endometriosis, who declared the presence of moderate or severe deep dyspareunia,...
Fri Oct 16, 2020 03:00
Abstract Healing wounds represent a major public health problem, mainly when it is infected. Besides that, the antibiotics misuse and overuse favor the development of bacterial resistance. This study evaluated the effects of antimicrobial photodynamic therapy (aPDT) combined with artificial skin on disinfection of infected skin wound in rats. Twenty-four Wistar rats were randomly distributed into 4 groups (n = 6): (i) control—untreated; (ii) aPDT—treated with curcumin-mediated...
Fri Oct 16, 2020 03:00
Publication date: September 2020Source: Clinical Therapeutics, Volume 42, Issue 9Author(s):
Sat Oct 17, 2020 16:50
Publication date: September 2020Source: Clinical Therapeutics, Volume 42, Issue 9Author(s):
Sat Oct 17, 2020 16:50
Publication date: Available online 17 October 2020Source: Journal of Neuroscience MethodsAuthor(s): Deng Pan, Junichi Sayanagi, Jesús A. Acevedo-Cintron, Lauren Schellhardt, Alison K. Snyder-Warwick, Susan E. Mackinnon, Matthew D. Wood
Sat Oct 17, 2020 16:43
Publication date: Available online 17 October 2020Source: Journal of Neuroscience MethodsAuthor(s): Komal Rani, Simran Rastogi, Poorvi Vishwakarma, Prahalad Singh Bharti, Vaibhav Sharma, Km Renu, Gyan P Modi, Venugopalan Y Vishnu, Prashun Chatterjee, Aparajit Ballav Dey, Fredrik Nikolajeff, Saroj Kumar
Sat Oct 17, 2020 16:43
Abstract Emerging evidence suggests that individuals with poor behavioral perseverance show low or blunted physiological responses to acute psychological stress. For example, a recent preliminary laboratory study demonstrated that blunted responders give up sooner and take fewer attempts when endeavoring to complete an impossible puzzle, but do not self‐report poor perseverance. This present research is a replication of the previous study with an increased sample size, longer recovery periods between...
Sat Oct 17, 2020 12:08
Publication date: Available online 16 October 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Satveer K. Mahil, Nick Dand, Kayleigh J. Mason, Zenas ZN. Yiu, Teresa Tsakok, Freya Meynell, Bola Coker, Helen McAteer, Lucy Moorhead, Teena Mackenzie, Maria Teresa Rossi, Raquel Rivera, Emmanuel Mahe, Andrea Carugno, Michela Magnano, Giulia Rech, Esther A. Balogh, Steven R. Feldman, Claudia De La Cruz, Siew Eng Choon
Sat Oct 17, 2020 16:12
Publication date: Available online 16 October 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Magali Noval Rivas, Rebecca A. Porritt, Mary Hongying Cheng, Ivet Bahar, Moshe Arditi
Fri Oct 16, 2020 21:08
Publication date: Available online 16 October 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Hemant R. Joshi, Harry R. Hill, Julie Asch., Qin Zhou, Rebecca Margraf, Emily Coonrod, Jacob Durtschi, Xiao He, Karl V. Voelkerding, Attila Kumánovics
Fri Oct 16, 2020 21:08
Publication date: Available online 16 October 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Pelin Sahlén, Rapolas Spalinskas, Samina Asad, Kunal Das Mahapatra, Pontus Höjer, Anandashankar Anil, Jesper Eisfeldt, Ankit Srivastava, Pernilla Nikamo, Anaya Mukherjee, Kyu-Han Kim, Otto Bergman, Mona Ståhle, Enikö Sonkoly, Andor Pivarcsi, Carl-Fredrik Wahlgren, Magnus Nordenskjöld, Fulya Taylan, Maria Bradley, Isabel Tapia-Páez
Fri Oct 16, 2020 21:08
Publication date: Available online 15 October 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Hang Li, Min Hyung Ryu, Christopher F. Rider, Wayne Tse, Rachel L. Clifford, Maria J. Aristizabal, Weiping Wen, Chris Carlsten
Fri Oct 16, 2020 21:08
Publication date: Available online 15 October 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Helen Kühn, Pavel Kolkhir, Magda Babina, Miriam Düll, Stefan Frischbutter, Jie Shen Fok, Qingqing Jiao, Martin Metz, Jörg Scheffel, Katharina Wolf, Andreas E. Kremer, Marcus Maurer
Fri Oct 16, 2020 21:08
Publication date: Available online 15 October 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Sunil Tomar, Varsha Ganesan, Ankit Sharma, Chang Zeng, Lisa Waggoner, Andrew Smith, Chang H. Kim, Paula Licona-Limón, Richard L. Reinhardt, Richard A. Flavell, Yui-Hsi Wang, Simon P. Hogan
Fri Oct 16, 2020 21:08
Supplemental oxygen is a supportive treatment in patients with sepsis to balance tissue oxygen delivery and demand in the tissues. However, hyperoxia may induce some pathological effects. We sought to assess organ damage associated with hyperoxia and its correlation with the production of reactive oxygen species (ROS) in a preclinical model of intra-abdominal sepsis. For this purpose, sepsis was induced in male, Sprague-Dawley rats by cecal ligation and puncture (CLP). We randomly assigned experimental...
Fri Oct 16, 2020 15:50
Cytokine-induced endothelial dysfunction leads to inflammation and vascular adhesion molecule production in retinal pigment epithelium (RPE) cells. Inflammation is a critical mediator in retinal degeneration (RD) diseases, including age-related macular degeneration (AMD), and RD progression may be prevented through anti-inflammatory activity in RPE cells. The flavonoid polyphenol luteolin (LU) has anti-inflammatory and antidiabetes activities, but its effects regarding retinal protection remain unknown....
Fri Oct 16, 2020 13:20
Sat Oct 17, 2020 15:58
Key points Cortical activity underlying movement‐evoked pain is not well understood, despite being a key symptom of chronic musculoskeletal pain. We combined HD‐EEG with a full‐body reaching paradigm in a virtual reality environment to assess cortical activity during movement‐evoked pain in cLBP. Movement‐evoked pain in individuals with cLBP was associated with longer reaction times, delayed peak velocity and greater movement variability. Movement‐evoked pain was associated with attenuated...
Sat Oct 17, 2020 15:58
Key points Regular exercise improves muscle functional capacity and clinical state of patients with idiopathic inflammatory myopathy (IIM). In our study, we used an in vitro model of human primary muscle cell cultures, derived from IIM patients before and after 6‐month intensive supervised training intervention, to assess the impact of disease and exercise on lipid metabolism dynamics. We provide evidence that muscle cells from IIM patients display altered dynamics of lipid metabolism and impaired...
Fri Oct 16, 2020 12:28
IgA vasculitis (formerly known as Henoch–Schönlein purpura or anaphylactoid purpura) is a usually benign vasculitis that affects children of school age. The disease is characterized by the tetrad of palpable purpura, arthralgia/arthritis, abdominal pain, and hematuria. Treatment of IgA vasculitis is mainly supportive, with administration of simple analgesics. Corticosteroids have been shown to reduce and/or ameliorate the occurrence of abdominal pain which may be severe. We present two children with...
Sat Oct 17, 2020 08:35
DeSanto-Shinawi syndrome is a rare genetic condition caused by loss-of-function mutation in WAC. It is characterized by dysmorphic features, intellectual disability, and behavioral abnormalities. In this case report, we describe the clinical features and genotype of a patient with a novel mutation 1346C > A in WAC. This patient’s dysmorphic features include a prominent forehead, bulbous nasal tip, macroglossia, deep-set eyes, and malar hypoplasia. This patient also showed signs of intellectual...
Fri Oct 16, 2020 17:20
Publication date: Available online 17 October 2020Source: Brain Research BulletinAuthor(s): Maria-Adriana Neag, Andrei-Otto Mitre, Adrian Catinean, Calin-Iosif Mitre
Sat Oct 17, 2020 15:55
Publication date: Available online 16 October 2020Source: Brain Research BulletinAuthor(s): Alhaddad Hasan, Alasmari Fawaz, Alhamadani Balsam, Wong Woonyen, L. Bell Richard, Sari Youssef
Sat Oct 17, 2020 15:55
Publication date: Available online 16 October 2020Source: Brain Research BulletinAuthor(s): Li Ma, Hui Zhang, Wen-zhi Guo, Lin-bo Jiao, Hong-yu Zhao, Ya-qun Ma, Xue-mei Hao
Sat Oct 17, 2020 15:55
Several national breast implant registries, designed as Clinical Quality Registries (CQRs), have been founded over the past decade, including Australia, Netherlands, Denmark, Sweden, the United States, the United Kingdom and Italy (Table 1). This occurred in response to worldwide breast implant controversies,1-3 and is supported by the European New regulation on Medical devices.4 More recently, questions about breast implant safety have been raised in mainstream and social media related to Breast...
Sat Oct 17, 2020 03:00
Publication date: Available online 17 October 2020Source: CortexAuthor(s): Mar Martín-Signes, Cristina Cano-Melle, Ana B. Chica
Sat Oct 17, 2020 15:37
Publication date: Available online 17 October 2020Source: CortexAuthor(s): John F. Magnotti, Kristen B. Dzeda, Kira Wegner-Clemens, Johannes Rennig, Michael S. Beauchamp
Sat Oct 17, 2020 15:37
Publication date: Available online 17 October 2020Source: CortexAuthor(s): Frederic R. Danion, James Mathew, Niels Gouirand, Eli Brenner
Sat Oct 17, 2020 15:37
Publication date: Available online 15 October 2020Source: CortexAuthor(s): Silvio Ionta, Marcello Costantini, Antonio Ferretti, Gaspare Galati, Gian Luca Romani, Salvatore M. Aglioti
Fri Oct 16, 2020 21:22
Abstract Background Severe Early Childhood Caries (S-ECC) is an aggressive form of tooth decay that often requires pediatric dental rehabilitative surgery. The Early Childhood Oral Health Impact Scale (ECOHIS) measures oral health-related quality of life (OHRQL). The purpose of this study was to determine whether there is an association between ECOHIS scores and surgery wait times for children undergoing dental treatment for S-ECC...
Sat Oct 17, 2020 03:00
Abstract Background Poor oral hygiene and high hormone levels during pregnancy can lead to a deterioration in periodontal health. This study assessed the effectiveness of a family-centered behavioral and educational counselling program on improving the periodontal health of women during pregnancy and postpartum. Methods A randomized controlled...
Fri Oct 16, 2020 03:00
Abstract Purpose This study aims to evaluate the best possible practice using hybrid volumetric modulated arc therapy (H-VMAT) for hypofractionated radiation therapy of breast cancer. Different combinations of H‑VMAT—a combination of three-dimensional radiotherapy (3D-CRT) and VMAT—were analyzed regarding planning target volume (PTV), dose coverage, and exposure to organs at risk (OAR). ...
Sat Oct 17, 2020 03:00
Abstract Purpose To quantify mean heart dose (MHD) and doses to the left anterior descending artery (LAD) and left ventricle (LV) in a retrospective series of patients who underwent perioperative accelerated partial breast irradiation with multicatheter interstitial brachytherapy (MIB-APBI). Methods Sixty-eight patients with low-risk left breast cancer...
Fri Oct 16, 2020 03:00
Publication date: Available online 16 October 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): M. Fieux, S. Duret, S. Tringali
Sat Oct 17, 2020 15:03
Publication date: Available online 15 October 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): P. Reynard, E. Ionescu, N. Goulème, J. Ortéga-Solis, K. Spruyt, H. Thai-Van
Fri Oct 16, 2020 19:02
New England Journal of Medicine, Ahead of Print.
Fri Oct 16, 2020 07:00
New England Journal of Medicine, Ahead of Print.
Fri Oct 16, 2020 07:00
Publication date: Available online 17 October 2020Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): Christopher A. Rayle, Mark A. Fritz
Sat Oct 17, 2020 14:15
Publication date: Available online 16 October 2020Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): Alexandra Shams Ortiz, Rodney K. Chan, Gregory R. Dion
Sat Oct 17, 2020 14:15
Publication date: Available online 16 October 2020Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): David Myssiorek, Ahmed M.S. Soliman
Fri Oct 16, 2020 19:12
Publication date: Available online 16 October 2020Source: Revue des Maladies RespiratoiresAuthor(s): C. Zied, H. Abdessalem, B. Ayed Ahmed, A. Walid, E. Nizar, F. Imed
Sat Oct 17, 2020 14:02
Publication date: Available online 16 October 2020Source: Revue des Maladies RespiratoiresAuthor(s): H. Knaz, I. Anane, F. Guezguez, C. Prefaut, H. Ben Saad
Fri Oct 16, 2020 19:45
Publication date: Available online 16 October 2020Source: Revue des Maladies RespiratoiresAuthor(s): N. Postel-Vinay, F.-X. Blanc, O. Steichen, B. Housset, P. Clerson, P. Eveillard, C. Leroyer, N. Roche
Fri Oct 16, 2020 19:45
Publication date: Available online 15 October 2020Source: Revue des Maladies RespiratoiresAuthor(s): M. Dahan
Fri Oct 16, 2020 19:45
Publication date: Available online 15 October 2020Source: Revue des Maladies RespiratoiresAuthor(s): F. Payen, A. Greil, D. Caillaud
Fri Oct 16, 2020 19:45
Publication date: Available online 15 October 2020Source: Revue des Maladies RespiratoiresAuthor(s): G. Treffel, A. Guillaumot, E. Gomez, M. Eyries, I. Petit, J.-F. Chabot, A. Chaouat
Fri Oct 16, 2020 19:45
Publication date: Available online 15 October 2020Source: Revue des Maladies RespiratoiresAuthor(s): L. Guilleminault, S. Grassin Delyle, S. Bruley Des Varannes, M. Migueres, L. De Gabory, D. Brouquières, R. Escamilla
Fri Oct 16, 2020 19:45
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