Late‐onset interstitial nephritis in a patient with drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms

Late‐onset interstitial nephritis in a patient with drug‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms:

Abstract

Drug‐induced hypersensitivity syndrome (DIHS), also referred to as drug reaction with eosinophilia and systemic symptoms (DRESS), is a severe hypersensitivity drug reaction affecting the skin and multiple internal organ systems. We report a 47‐year‐old man with DIHS/DRESS and comorbidities (fulminant type 1 diabetes mellitus, valsartan‐induced photosensitivity, vitiligo and acute interstitial nephritis). Although acute interstitial nephritis usually appears in the early phase, his is a rare case of acute interstitial nephritis more than 2 years after the onset of DIHS/DRESS.