IJERPH, Vol. 16, Pages 5156: Rainfall Trends and Malaria Occurrences in Limpopo Province, South Africa International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16245156 Authors: Abiodun Adeola Katlego Ncongwane Gbenga Abiodun Thabo Makgoale Hannes Rautenbach Joel Botai Omolola Adisa Christina Botai This contribution aims to investigate the influence of monthly total rainfall variations on malaria transmission in the Limpopo Province. For...
Tue Dec 17, 2019 02:00
IJERPH, Vol. 16, Pages 5154: Effects of Backpacks on Ground Reaction Forces in Children of Different Ages When Walking, Running, and Jumping International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16245154 Authors: João P. Barbosa Mário C. Marques Henrique P. Neiva Dulce Esteves Alicia M Alonso-Martínez Mikel Izquierdo Rodrigo Ramirez-Campillo Cristian Alvarez Daniel A. Marinho Backpacks for transporting school loads are heavily utilized...
Tue Dec 17, 2019 02:00
IJERPH, Vol. 16, Pages 5151: Application of the JA-CHRODIS Integrated Multimorbidity Care Model (IMCM) to a Case Study of Diabetes and Mental Health International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16245151 Authors: Maria Forjaz Carmen Rodriguez-Blazquez Inmaculada Guerrero-Fernández de Alba Antonio Gimeno-Miguel Kevin Bliek-Bueno Alexandra Prados-Torres on behalf of the CHRODIS Expert Group on Multimorbidity The Integrated Multimorbidity...
Tue Dec 17, 2019 02:00
IJERPH, Vol. 16, Pages 5155: Effects of an Educational Intervention on Angolan Adolescents’ Knowledge of Human Reproduction: A Quasi-Experimental Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16245155 Authors: Natércia Almeida Andreia Teixeira José Garcia Natália Martins Carla Ramalho Background and objectives: Sex education is a necessity and a right of young people in Angola. However, this education is deficient or even absent...
Tue Dec 17, 2019 02:00
IJERPH, Vol. 16, Pages 5152: A Hypothesis and Evidence That Mercury May be an Etiological Factor in Alzheimer’s Disease International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16245152 Authors: Robert Siblerud Joachim Mutter Elaine Moore Johannes Naumann Harald Walach Mercury is one of the most toxic elements and causes a multitude of health problems. It is ten times more toxic to neurons than lead. This study was created to determine if mercury...
Tue Dec 17, 2019 02:00
IJERPH, Vol. 16, Pages 5150: Psychosocial Stress, Sedentary Behavior, and Physical Activity during Pregnancy among Canadian Women: Relationships in a Diverse Cohort and a Nationwide Sample International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16245150 Authors: Isabelle Sinclair Myriane St-Pierre Guillaume Elgbeili Paquito Bernard Cathy Vaillancourt Sonia Gagnon Kelsey Needham Dancause Background: Past research shows that psychosocial stress...
Tue Dec 17, 2019 02:00
IJMS, Vol. 21, Pages 1: Phenolic Compounds with Antioxidant Properties from Canola Meal Extracts Inhibit Adipogenesis International Journal of Molecular Sciences doi: 10.3390/ijms21010001 Authors: Saira Hussain Ata Ur Rehman David J. Luckett Christopher L. Blanchard Hassan K. Obied Padraig Strappe The extraction of phenolic compounds from canola meal produces functional health products and renders the canola meal a more digestible animal feed. The extracted phenolics may...
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IJMS, Vol. 20, Pages 6364: S1P/S1P Receptor Signaling in Neuromuscolar Disorders International Journal of Molecular Sciences doi: 10.3390/ijms20246364 Authors: Meacci Garcia-Gil The bioactive sphingolipid metabolite, sphingosine 1-phosphate (S1P), and the signaling pathways triggered by its binding to specific G protein-coupled receptors play a critical regulatory role in many pathophysiological processes, including skeletal muscle and nervous system degeneration. The signaling...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6363: Cardiac Extracellular Vesicles (EVs) Released in the Presence or Absence of Inflammatory Cues Support Angiogenesis in Different Manners International Journal of Molecular Sciences doi: 10.3390/ijms20246363 Authors: Christien Madlen Beez Maria Schneider Marion Haag Kathleen Pappritz Sophie Van Linthout Michael Sittinger Martina Seifert Cells release extracellular vesicles (EVs) to communicate in a paracrine manner with other cells, and thereby...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6365: “Salicylic Acid Mutant Collection” as a Tool to Explore the Role of Salicylic Acid in Regulation of Plant Growth under a Changing Environment International Journal of Molecular Sciences doi: 10.3390/ijms20246365 Authors: Pluhařová Leontovyčová Stoudková Pospíchalová Maršík Klouček Starodubtseva Iakovenko Krčková Valentová Burketová Janda Kalachova The hytohormone salicylic acid (SA) has a crucial role in plant...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6361: Sphingosine-1-Phosphate Enhances α1-Adrenergic Vasoconstriction via S1P2–G12/13–ROCK Mediated Signaling International Journal of Molecular Sciences doi: 10.3390/ijms20246361 Authors: Cecília R. Panta Éva Ruisanchez Dorottya Móré Péter T. Dancs Andrea Balogh Ágnes Fülöp Margit Kerék Richard L. Proia Stefan Offermanns Gábor J. Tigyi Zoltán Benyó Sphingosine-1-phosphate (S1P) has been implicated recently in the physiology and pathology...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6362: Vascular Diseases and Gangliosides International Journal of Molecular Sciences doi: 10.3390/ijms20246362 Authors: Norihiko Sasaki Masashi Toyoda Vascular diseases, such as myocardial infarction and cerebral infarction, are most commonly caused by atherosclerosis, one of the leading causes of death worldwide. Risk factors for atherosclerosis include lifestyle and aging. It has been reported that lifespan could be extended in mice by targeting senescent cells,...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6360: Increase in IGF-1 Expression in the Injured Infraorbital Nerve and Possible Implications for Orofacial Neuropathic Pain International Journal of Molecular Sciences doi: 10.3390/ijms20246360 Authors: Shiori Sugawara Masamichi Shinoda Yoshinori Hayashi Hiroto Saito Sayaka Asano Asako Kubo Ikuko Shibuta Akihiko Furukawa Akira Toyofuku Koichi Iwata Insulin-like growth factor-1 (IGF-1) is upregulated in the injured peripheral nerve bundle...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6359: Proteomics Analysis of Early Developmental Stages of Zebrafish Embryos International Journal of Molecular Sciences doi: 10.3390/ijms20246359 Authors: Kathiresan Purushothaman Prem Prakash Das Christopher Presslauer Teck Kwang Lim Steinar D. Johansen Qingsong Lin Igor Babiak Zebrafish is a well-recognized organism for investigating vertebrate development and human diseases. However, the data on zebrafish proteome are scarce, particularly during...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6357: Bioactive Polyphenols Modulate Enzymes Involved in Grapevine Pathogenesis and Chitinase Activity at Increasing Complexity Levels International Journal of Molecular Sciences doi: 10.3390/ijms20246357 Authors: Antonio Filippi Elisa Petrussa Francesco Boscutti Marco Vuerich Urska Vrhovsek Zohreh Rabiei Enrico Braidot The reduction of synthetic chemistry use in modern viticulture relies on either the biological control of microorganisms or the...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6358: Targeting microRNAs as a Therapeutic Strategy to Reduce Oxidative Stress in Diabetes International Journal of Molecular Sciences doi: 10.3390/ijms20246358 Authors: Giuseppina Emanuela Grieco Noemi Brusco Giada Licata Laura Nigi Caterina Formichi Francesco Dotta Guido Sebastiani Diabetes mellitus is a group of heterogeneous metabolic disorders characterized by chronic hyperglycaemia as a consequence of pancreatic β cell loss and/or...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6356: The Monetite Structure Probed by Advanced Solid-State NMR Experimentation at Fast Magic-Angle Spinning International Journal of Molecular Sciences doi: 10.3390/ijms20246356 Authors: Yang Yu Baltzar Stevensson Michael Pujari-Palmer Hua Guo Håkan Engqvist Mattias Edén We present a solid-state nuclear magnetic resonance (NMR) spectroscopy study of the local 31 P and 1 H environments in monetite [CaHPO 4 ; dicalcium phosphate...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6354: The Ubiquitin Proteasome System in Ischemic and Dilated Cardiomyopathy International Journal of Molecular Sciences doi: 10.3390/ijms20246354 Authors: Sabine Spänig Kristina Kellermann Maja-Theresa Dieterlen Thilo Noack Sven Lehmann Michael A. Borger Jens Garbade Yaron D. Barac Fabian Emrich Dilated (DCM) and ischemic cardiomyopathies (ICM) are associated with cardiac remodeling, where the ubiquitin–proteasome system (UPS) holds...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6355: Formin-like 1 (FMNL1) Is Associated with Glioblastoma Multiforme Mesenchymal Subtype and Independently Predicts Poor Prognosis International Journal of Molecular Sciences doi: 10.3390/ijms20246355 Authors: Nayuta Higa Yoshinari Shinsato Muhammad Kamil Takuro Hirano Tomoko Takajo Michiko Shimokawa Kentaro Minami Masatatsu Yamamoto Kohichi Kawahara Hajime Yonezawa Hirofumi Hirano Tatsuhiko Furukawa Koji Yoshimoto Kazunori Arita...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6353: Pseudoxanthoma Elasticum, Kidney Stones and Pyrophosphate: From a Rare Disease to Urolithiasis and Vascular Calcifications International Journal of Molecular Sciences doi: 10.3390/ijms20246353 Authors: Emmanuel Letavernier Elise Bouderlique Jeremy Zaworski Ludovic Martin Michel Daudon Pseudoxanthoma elasticum is a rare disease mainly due to ABCC6 gene mutations and characterized by ectopic biomineralization and fragmentation of elastic fibers resulting...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6352: Editorial of Special Issue “Surface-Functionalized Nanoparticles as Drug Carriers” International Journal of Molecular Sciences doi: 10.3390/ijms20246352 Authors: Buddhadev Layek Jagdish Singh Safe and effective delivery of therapeutics at the target site is the key to successful therapy. Nanocarriers can offer significant advantages over conventional dosage forms. Over the decades, nanoparticles have been extensively used to increase bioavailability, improve...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6351: Pericytes in Microvessels: From “Mural” Function to Brain and Retina Regeneration International Journal of Molecular Sciences doi: 10.3390/ijms20246351 Authors: Nunzia Caporarello Floriana D’Angeli Maria Teresa Cambria Saverio Candido Cesarina Giallongo Mario Salmeri Cinzia Lombardo Anna Longo Giovanni Giurdanella Carmelina Daniela Anfuso Gabriella Lupo Pericytes are branched cells located in the wall of capillary blood vessels...
Tue Dec 17, 2019 02:00
IJMS, Vol. 20, Pages 6350: Single-Molecule Long-Read Sequencing Reveals the Diversity of Full-Length Transcripts in Leaves of Gnetum (Gnetales) International Journal of Molecular Sciences doi: 10.3390/ijms20246350 Authors: Nan Deng Chen Hou Fengfeng Ma Caixia Liu Yuxin Tian The limitations of RNA sequencing make it difficult to accurately predict alternative splicing (AS) and alternative polyadenylation (APA) events and long non-coding RNAs (lncRNAs), all of which reveal...
Tue Dec 17, 2019 02:00
JCM, Vol. 9, Pages 2: Bone Marrow-Derived Mesenchymal Stromal Cells: A Novel Target to Optimize Hematopoietic Stem Cell Transplantation Protocols in Hematological Malignancies and Rare Genetic Disorders Journal of Clinical Medicine doi: 10.3390/jcm9010002 Authors: Crippa Santi Bosotti Porro Bernardo : Mesenchymal stromal cells (MSCs) are crucial elements in the bone marrow (BM) niche where they provide physical support and secrete soluble factors to control and maintain...
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JCM, Vol. 9, Pages 1: Obstructive Sleep Apnea as a Predictor of Abnormal Heart Rate Turbulence Journal of Clinical Medicine doi: 10.3390/jcm9010001 Authors: Urbanik Gać Martynowicz Poręba Podgórski Negrusz-Kawecka Mazur Sobieszczańska Poręba Obstructive sleep apnea (OSA) causes dysfunction of the autonomic nervous system, but the exact mechanism has not been fully understood. The aim of this study was to analyse the relationship between the incidence...
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JCM, Vol. 8, Pages 2230: Neopterin is Associated with Disease Severity and Outcome in Patients with Non-Ischaemic Heart Failure Journal of Clinical Medicine doi: 10.3390/jcm8122230 Authors: Lukas Lanser Gerhard Pölzl Dietmar Fuchs Günter Weiss Katharina Kurz Inflammation and immune activation play an important role in the pathogenesis of cardiac remodelling in patients with heart failure. The aim of this study was to assess whether biomarkers of inflammation and immune activation...
Tue Dec 17, 2019 02:00
JCM, Vol. 8, Pages 2231: Effects of Perioperative Magnesium Sulfate Administration on Postoperative Chronic Knee Pain in Patients Undergoing Total Knee Arthroplasty: A Retrospective Evaluation Journal of Clinical Medicine doi: 10.3390/jcm8122231 Authors: Tak Kyu Oh Seung Hyun Chung Jinwoo Park Hyunjung Shin Chong Bum Chang Tae Kyun Kim Sang-Hwan Do We aimed to investigate whether perioperative magnesium sulfate administration was associated with the incidence of chronic...
Tue Dec 17, 2019 02:00
JCM, Vol. 8, Pages 2229: Trials of a Fluorescent Endoscopic Video System for Diagnosis and Treatment of the Head and Neck Cancer Journal of Clinical Medicine doi: 10.3390/jcm8122229 Authors: Dina Farrakhova Artem Shiryaev Dmitry Yakovlev Kanamat Efendiev Yulia Maklygina Alexandr Borodkin Maxim Loschenov Lina Bezdetnaya Anastasia Ryabova Liana Amirkhanova Svetlana Samoylova Mikhail Rusakov Victor Zavodnov Vladimir Levkin Igor Reshetov Victor Loschenov...
Tue Dec 17, 2019 02:00
JCM, Vol. 8, Pages 2227: The Role of the Gut Microbiota in Lipid and Lipoprotein Metabolism Journal of Clinical Medicine doi: 10.3390/jcm8122227 Authors: Yijing Yu Fitore Raka Khosrow Adeli Both environmental and genetic factors contribute to relative species abundance and metabolic characteristics of the intestinal microbiota. The intestinal microbiota and accompanying microbial metabolites differ substantially in those who are obese or have other metabolic disorders. Accumulating...
Tue Dec 17, 2019 02:00
JCM, Vol. 8, Pages 2228: Effectiveness and Safety of Direct Oral Anticoagulant for Secondary Prevention in Asians with Atrial Fibrillation Journal of Clinical Medicine doi: 10.3390/jcm8122228 Authors: Jiesuck Park So-Ryoung Lee Eue-Keun Choi Soonil Kwon Jin-Hyung Jung Kyung-Do Han Myung-Jin Cha Sang-Bae Ko Seil Oh Gregory Y. H. Lip We investigated the effectiveness and safety of direct oral anticoagulants (DOACs) for secondary prevention in patients with atrial...
Tue Dec 17, 2019 02:00
JFB, Vol. 10, Pages 56: Understanding the Role of Shape and Composition of Star-Shaped Polymers and their Ability to Both Bind and Prevent Bacteria Attachment on Oral Relevant Surfaces Journal of Functional Biomaterials doi: 10.3390/jfb10040056 Authors: Hamid Mortazavian Guillaume A. Picquet Jānis Lejnieks Lynette A. Zaidel Carl P. Myers Kenichi Kuroda In this study, we have prepared a series of 4- and 6-arm star-shaped polymers with varying molecular weight and hydrophobicity...
Tue Dec 17, 2019 02:00
Membranes, Vol. 9, Pages 172: Research on Operation Efficiency and Membrane Fouling of A2/O-MBR in Reclaimed Water Treatment Membranes doi: 10.3390/membranes9120172 Authors: Fenfen Li Xinyue An Cuimin Feng Jianwei Kang Junling Wang Hongying Yu Taking the public building domestic wastewater as an example, the combination of the MBR (membrane bioreactor) process and the traditional A2/O (anaerobic-anoxic-oxic) process was established and analyzed in terms of the removal...
Tue Dec 17, 2019 02:00
Metabolites, Vol. 9, Pages 308: From Samples to Insights into Metabolism: Uncovering Biologically Relevant Information in LC-HRMS Metabolomics Data Metabolites doi: 10.3390/metabo9120308 Authors: Ivanisevic Want Untargeted metabolomics (including lipidomics) is a holistic approach to biomarker discovery and mechanistic insights into disease onset and progression, and response to intervention. Each step of the analytical and statistical pipeline is crucial for the generation of high-quality,...
Tue Dec 17, 2019 02:00
Metabolites, Vol. 9, Pages 307: Soluble Sugar and Lipid Readjustments in the Yarrowia lipolytica Yeast at Various Temperatures and pH Metabolites doi: 10.3390/metabo9120307 Authors: Varvara Yu Sekova Daria I. Dergacheva Elena P. Isakova Natalya N. Gessler Vera M. Tereshina Yulia I. Deryabina Microorganisms cope with a wide range of environmental challenges using different mechanisms. Their ability to prosper at extreme ambient pH and high temperatures has been well reported,...
Tue Dec 17, 2019 02:00
Metabolites, Vol. 9, Pages 306: Barth Syndrome: Exploring Cardiac Metabolism with Induced Pluripotent Stem Cell-Derived Cardiomyocytes Metabolites doi: 10.3390/metabo9120306 Authors: Erica M. Fatica Gina A. DeLeonibus Alisha House Jillian V. Kodger Ryan W. Pearce Rohan R. Shah Liraz Levi Yana Sandlers Barth syndrome (BTHS) is an X-linked recessive multisystem disorder caused by mutations in the TAZ gene (TAZ, G 4.5, OMIM 300394) that encodes for the acyltransferase...
Tue Dec 17, 2019 02:00
Metabolites, Vol. 9, Pages 305: Impact of Bovine Diet on Metabolomic Profile of Skim Milk and Whey Protein Ingredients Metabolites doi: 10.3390/metabo9120305 Authors: Jonathan B. Magan Tom F. O’Callaghan Jiamin Zheng Lun Zhang Rupasri Mandal Deirdre Hennessy Mark A. Fenelon David S. Wishart Alan L. Kelly Noel A. McCarthy The influence of bovine diet on the metabolome of reconstituted skim milk powder (SMP) and protein ingredients produced from the milk of cows...
Tue Dec 17, 2019 02:00
Microorganisms, Vol. 7, Pages 713: Metagenomic Insights into the Effects of Seasonal Temperature Variation on the Activities of Activated Sludge Microorganisms doi: 10.3390/microorganisms7120713 Authors: Ai Yan Zhou Hou Chai Qiu Zeng It is well acknowledged that the activities of activated sludge (AS) are influenced by seasonal temperature variation. However, the underlying mechanisms remain largely unknown. Here, the activities of activated sludge under three...
Tue Dec 17, 2019 02:00
Microorganisms, Vol. 7, Pages 710: Effects of Linoleic Acid on Gut-Derived Bifidobacterium breve DSM 20213: A Transcriptomic Approach Microorganisms doi: 10.3390/microorganisms7120710 Authors: Alice Senizza Maria Luisa Callegari Biancamaria Senizza Andrea Minuti Gabriele Rocchetti Lorenzo Morelli Vania Patrone Bacterial production of conjugated linoleic acid (CLA) has recently received great attention because of the potential health benefits of this fatty acid. Linoleic...
Tue Dec 17, 2019 02:00
Microorganisms, Vol. 7, Pages 711: High Kanamycin Concentration as Another Stress Factor Additional to Temperature to Increase pDNA Production in E. coli DH5α Batch and Fed-Batch Cultures Microorganisms doi: 10.3390/microorganisms7120711 Authors: Fernando Grijalva-Hernández Jesús Vega-Estrada Montserrat Escobar-Rosales Jaime Ortega-López Ricardo Aguilar-López Alvaro R. Lara Ma. del Carmen Montes-Horcasitas Plasmid DNA (pDNA) vaccines require high supercoiled-pDNA doses...
Tue Dec 17, 2019 02:00
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