Prevalence of skin diseases in children admitted to mersin university school of medicine, dermatology clinic Pinar Dursun, Guliz Ikizoglu Turkish Journal of Dermatology 2019 13(4):123-125 Objective: Skin disorders constitute an important problem in children living in developing countries. The aim of the study was to evaluate the prevalence of skin diseases in children aged 0–16 years. Materials and Methods: In the present study, data on a total of 12,206 children aged 0–16 years, admitted to the outpatient clinic of Dermatology Department, Mersin University School of Medicine, between 2001 and 2010 were analyzed. Results: Male/female ratio was 1.1/1. 44.2% of the patients were adolescents. The most common diseases were acne (12.4%), warts (10.5%), and atopic dermatitis (9.3%). Conclusion: Studies of the pediatric population, which constitutes the cornerstone of the community, can play an important role in determining the policies of protective medicine and public health.

Effectiveness of combined 10,600 nm fractional CO2and 1540 nm erbium GaAs laser therapy on acne scar score alteration in patients with atrophic acne scars Erien Afrinia Asri, Retno Indar Widayati, Dian Adriani Malik Turkish Journal of Dermatology 2019 13(4):126-130 Aim: The aim of this study is to determine the effectiveness of combined 10,600 nm fractional CO2and 1540 nm erbium GaAs laser therapy on atrophic acne scars. Subjects and Methods: The design of this study was pre- and post-test on patients with atrophic acne scars before and after receiving the combination laser therapy of fractional CO2and erbium GaAs. The sample size consisted of 20 medical records. The Acne Goodman-Baron Scar Score was used to score acne scars, which included morphology, quantity, depth, and width of the acne scars. The therapy was administered three times at 1-month intervals. The power and wavelength of the laser were adjusted based on the degree of the severity of the acne scar in each patient. The data were analyzed the hypothesis statistically using the Wilcoxon test, using the SPSS for Windows program, version 16.0. Results: There were significant differences (P = 0.007) between the means of the Goodman–Baron acne scar scores before and after combined 10,600 nm fractional CO2and 1540 nm erbium GaAs laser therapy. Side effects occurred in 50% of patients, where 35% experienced erythema and 15% experienced pruritus. Conclusion: The combination of 1540 nm erbium GaAs and 10,600 nm fractional CO2laser therapy can be effective for treating atrophic acne scars on the face, with minimal side effects. However, longer therapy sessions are required for better results.

Thiol/disulfide homeostasis in patients with telogen effluvium: is oxidative stress important in the pathogenesis of telogen effluvium? Unsal Savci, Mustafa Sahin, Engin Senel, Aynure Oztekin, Umran Muslu, Mustafa Sungur, Salim Neselioglu, Ozcan Erel Turkish Journal of Dermatology 2019 13(4):131-134 Objective: The aim of this study was to assess the correlation between telogen effluvium (TE) with the new oxidative stress (OS) indicator of thiol/disulfide balance and to research the role of OS in the pathogenesis of TE. Methods: Our study included 101 patients with TE diagnosis and 39 healthy individuals. Serum thiol/disulfide was measured with a new automated spectrometric method developed by Erel and Neselioglu, and results were compared statistically. Results: Among the six thiol/disulfide parameters, there were statistically significant differences for native thiol, total thiol, disulfide, disulfide/native thiol, disulfide/total thiol, and native thiol/total thiol studied in the patient and control groups (P &#61; 0.042, 0.044, &#60;0.001, 0.013, 0.026, and < 0.001, respectively). Conclusions: Based on the results of this study, it can be said that OS is closely associated with TE pathogenesis. There is a need for new studies that will show the possible effects of OS on TE pathogenesis and research different OS markers in addition to thiol/disulfide parameters.

Dermoscopy of oral labial mucosa according to age and sex in healthy adults: first observational dermoscopic study Erhan Ayhan, Murat &#214;zt&#252;rk, Isa An, E&#351;ref Ara&#231; Turkish Journal of Dermatology 2019 13(4):135-139 Background/Aim: Information on dermoscopy of the labial mucosa is limited to dermoscopic examination of several dermatological diseases of the labial mucosa. In this study, we investigated whether dermoscopic features of labial mucosa differ in age and sex in healthy individuals. Materials and Methods: The study included 152 healthy individuals (76 females and 76 males) aged between 20 and 83 years who applied to the outpatient dermatology department. For the evaluation of dermoscopic features, the patients were divided into two groups as age under 40 years (Group 1) and over 40 years (Group 2). Dermoscopic data were analyzed by age and sex. Results: In Group 1, clear reticular arrangement (40.4&#37; vs. 13.8&#37;, P &#61; 0.001) and honeycomb appearance (7.4&#37; vs. 0&#37;, P &#61; 0.033) were significant. In Group 2, mixed reticular arrangement (61.7&#37; vs. 82.8&#37;, P &#61; 0.006), grouped hairpin vessels (48.9&#37; vs. 69&#37;, P &#61; 0.016), yellow background areas (87.2&#37; vs. 98.3&#37;, P &#61; 0.018), dotted vessels (33&#37; vs. 62.1&#37;, P &#61; 0.000), matchstick hairpin vessels (6.4&#37; vs. 19&#37;, P &#61; 0.017), microaneurysm (3.2&#37; vs. 32.8&#37;, P &#61; 0.000) were significant. While clear reticular arrangement and purple areas were more common in females, mixed reticular pattern and grouped hairpin vessels were more frequent in males. Conclusion: In this study, significant differences were found in dermoscopic features according to age and sex in healthy individuals. These results will serve as the basis for studies on the effect of systemic diseases on oral labial mucosa and studies on localized mucosal diseases.