Τρίτη 20 Οκτωβρίου 2020

 

Presence of dynapenia and association with anthropometric variables in cancer patients
Dynapenia is defined as an age-related loss of muscle strength. There is little information on dynapenia in cancer patients and on how it relates to anthropometric variables. The aim of this study was to analy... (Source: BMC Cancer)
BMC Cancer
11h
Seeking healthcare at their ‘right’ time; the iterative decision process for women with breast cancer
About 85% of breast cancer patients attending Komfo Anokye Teaching Hospital (KATH), Ghana, present with stage III/IV disease. In spite of great investments into the early diagnosis and management of breast ca... (Source: BMC Cancer)
BMC Cancer
11h
Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods
In recent years, the differences between left-sided colon cancer (LCC) and right-sided colon cancer (RCC) have received increasing attention due to the clinicopathological variation between them. However, some... (Source: BMC Cancer)
BMC Cancer
11h
Longitudinal changes in sports activity from pre-diagnosis to first five years post-diagnosis: a prospective Chinese breast cancer cohort study
To compare change in level of physical activity between pre-and post- diagnosis of breast cancer in Chinese women. (Source: BMC Cancer)
BMC Cancer
11h
A Swedish Nationwide prospective study of oncological and reproductive outcome following fertility-sparing surgery for treatment of early stage epithelial ovarian cancer in young women
Epithelial ovarian cancer (EOC) is rare in women of reproductive age and fertility-sparing surgery (FSS) may be applied in early stages. The purpose of this study was to investigate the safety and efficacy of ... (Source: BMC Cancer)
BMC Cancer
11h
Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway
Alternatively-activated macrophages (AAMs), an anti-inflammatory macrophage subpopulation, have been implicated in the progression of high grade serous ovarian carcinoma (HGSOC). Increased levels of AAMs are c... (Source: BMC Cancer)
BMC Cancer
11h
Inducing multiple antibodies to treat squamous cell esophageal carcinoma
The positive response and the clinical usefulness of 14 serum antibodies in patients with esophageal squamous cell carcinoma (ESCC) were examined in this study. The Cancer Genome Atlas (TCGA) was used to inves... (Source: BMC Cancer)
BMC Cancer
11h
Role of circulating free DNA in evaluating clinical tumor burden and predicting survival in Chinese metastatic colorectal cancer patients
The aim of this study was to explore the utility of circulating free DNA (cfDNA) in the evaluation of clinical tumor burden and survival in Chinese patients with metastatic colorectal cancer (mCRC) and to prel... (Source: BMC Cancer)
BMC Cancer
4d
CircRNAs as potential biomarkers for the clinicopathology and prognosis of glioma patients: a meta-analysis
An increasing number of studies have reported circular RNAs (circRNAs) as new potential biomarkers for the prognosis of gliomas. However, the overall prognostic value of circRNAs for glioma remains unclear. Th... (Source: BMC Cancer)
BMC Cancer
4d
Detection of MCM5 as a novel non-invasive aid for the diagnosis of endometrial and ovarian tumours
MCM5 is a protein involved in DNA replication, facilitating cell proliferation. In normal epithelium MCM5 expression is restricted to the cells in the basal proliferative compartments, however in the presence ... (Source: BMC Cancer)
BMC Cancer
4d
Biomarker exploration of microRNA-203 as a promising substrate for predicting poor survival outcome in colorectal cancer
Increasing studies indicated that microRNA-203 (miR-203) may play an important part in the prognosis of CRC. Nevertheless, the prognostic and influential mechanism of miR-203 expression in CRC remains to be in... (Source: BMC Cancer)
BMC Cancer
4d
CKD-5, a novel pan-histone deacetylase inhibitor, synergistically enhances the efficacy of sorafenib for hepatocellular carcinoma
Histone deacetylase inhibitors (HDACIs) have distinctive epigenetic targets involved in hepatocarcinogenesis and chemoresistance. A recent phase I/II study reported the possibility of HDACI as a chemosensitize... (Source: BMC Cancer)
BMC Cancer
4d
Impact of pre-existing cardiovascular disease on treatment patterns and survival outcomes in patients with lung cancer
This study aimed to characterize treatment trends and survival outcomes of patien... (Source: BMC Cancer)
BMC Cancer
4d
Limb salvage versus amputation in patients with osteosarcoma of the extremities: an update in the modern era using the National Cancer Database
Historically, amputation was the primary surgical treatment for osteosarcoma of the extremities; however, with advancements in surgical techniques and chemotherapies limb salvage has replaced amputation as the... (Source: BMC Cancer)
BMC Cancer
4d
YB-1 transferred by gastric cancer exosomes promotes angiogenesis via enhancing the expression of angiogenic factors in vascular endothelial cells
Angiogenesis is important for the progression of gastric cancer (GC). Y-box binding protein 1 (YB-1) predicts advanced disease and indicates neovasculature formation in GC tissues, while the related mechanisms... (Source: BMC Cancer)
BMC Cancer
4d
USP6NL mediated by LINC00689/miR-142-3p promotes the development of triple-negative breast cancer
Triple-negative breast cancer (TNBC), in part because of the high metastasis rate, is one of the most prevalent causes of malignancy-related mortality globally. Ubiquitin specific peptidase 6  N-terminal like (... (Source: BMC Cancer)
BMC Cancer
4d
Analysis of the role of the human papillomavirus 16/18 E7 protein assay in screening for cervical intraepithelial neoplasia: a case control study
Cervical cancer is the second-most common gynecological cancer, early screening plays a key role in the diagnosis and treatment of cervical intraepithelial neoplasia (CIN). Sustained E7 protein expression is t... (Source: BMC Cancer)
BMC Cancer
4d
Clinical characteristics and prognostic implications of BRCA-associated tumors in males: a pan-tumor survey
The BRCA mutation (BRCAm) in males has been reported to confer a higher risk for the development of various tumors. However, little is known about its clinicopathologic features and prognostic implications. (Source: BMC Cancer)
BMC Cancer
4d
Cost-effectiveness analysis of fruquintinib for metastatic colorectal cancer third-line treatment in China
In this study, we analyze the cost-effectiveness of fruquintinib as third-line treatment for patients with metastatic colorectal cancer in China, especially after a recent price drop suggested by the National ... (Source: BMC Cancer)
BMC Cancer
1w
Impact of concomitant systemic treatments on toxicity and intracerebral response after stereotactic radiotherapy for brain metastases
The aim of this study was to determine the safety and efficacy of fractionated stereotactic radiotherapy (SRT) in combination with systemic therapies (ST) for brain metastases (BM). (Source: BMC Cancer)
BMC Cancer
1w
Cost-effectiveness of brentuximab vedotin in advanced stage Hodgkin ’s lymphoma: a probabilistic analysis
Treatment with ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) is a well-established therapy for advanced Hodgkin ’s lymphoma (HL). However, the recently completed ECHELON-1 trial showed potential n... (Source: BMC Cancer)
BMC Cancer
1w
Relationship between formulaic breast volume and risk of breast cancer based on linear measurements
This study aimed to evaluate whether a significant association between breast volume and risk of breast cancer, based on linear measur... (Source: BMC Cancer)
BMC Cancer
1w
Cancer in Moroccan elderly: the first multicenter transverse study exploring the sociodemographic characteristics, clinical profile and quality of life of elderly Moroccan cancer patients
Moroccan incidence of cancer is increasing with the lengthening of life expectancy. Data regarding elderly Moroccan cancer patients are lacking. In the context of our project aiming to develop an adapted versi... (Source: BMC Cancer)
BMC Cancer
1w
A nomogram for predicting survival in patients with de novo metastatic breast cancer: a population-based study
This study aimed to develop a nomogram to predict the overall survival (OS) of these patients. (Source: BMC Cancer)
BMC Cancer
1w
The Axin2-snail axis promotes bone invasion by activating cancer-associated fibroblasts in oral squamous cell carcinoma
In bone-invasive oral squamous cell carcinoma (OSCC), cancer-associated fibroblasts (CAFs) infiltrate into bony tissue ahead of OSCC cells. In the present study, we aimed to investigate the role of the Axin2-S... (Source: BMC Cancer)
BMC Cancer
1w
ECCDIA: an interactive web tool for the comprehensive analysis of clinical and survival data of esophageal cancer patients
Esophageal cancer (EC) is considered as one of the deadliest malignancies with respect to incidence and mortality rate, and numerous risk factors may affect the prognosis of EC patients. For better understandi... (Source: BMC Cancer)
BMC Cancer
1w
The prognostic significance of inflammation-based scores in patients with ampullary carcinoma after pancreaticoduodenectomy
Growing evidence indicates that the systemic inflammatory response plays an important role in cancer development and progression. Several inflammatory markers have been reported to be associated with clinical ... (Source: BMC Cancer)
BMC Cancer
1w
Clinical and imaging characteristics of primary hepatic sarcomatoid carcinoma and sarcoma: a comparative study
Primary hepatic sarcomatous carcinoma (PHSC) and primary hepatic sarcoma (PHS) are rare malignancies with frequent overlap in both the clinic and radiology. No comparative study of these tumors for the restric... (Source: BMC Cancer)
BMC Cancer
1w
Treatment outcome and long-term follow-up of central nervous system germ cell tumor using upfront chemotherapy with subsequent photon or proton radiation therapy: a single tertiary center experience of 127 patients
Central nervous system germ cell tumors (CNS GCTs) are a heterogeneous group of brain tumors, which are more common in Asian countries. There have been different therapeutic strategies in treating germinoma an... (Source: BMC Cancer)
BMC Cancer
1w
Is hypofractionated whole pelvis radiotherapy (WPRT) as well tolerated as conventionally fractionated WPRT in prostate cancer patients? The HOPE trial
Patients with high-risk prostate cancer are at increased risk of lymph node metastasis and are thought to benefit from whole pelvis radiotherapy (WPRT). There has been recent interest in the use of hypofractio... (Source: BMC Cancer)
BMC Cancer
1w
Genetic variants in MIR17HG affect the susceptibility and prognosis of glioma in a Chinese Han population
lncRNA MIR17HG was upregulated in glioma, and participated in promoting proliferation, migration and invasion of glioma. However, the role of MIR17HG polymorphisms in the occurrence and prognosis of glioma is sti... (Source: BMC Cancer)
BMC Cancer
1w
Role of a multidisciplinary team in administering radiotherapy for esophageal cancer
Radiotherapy (RT) is the major part of the treatment strategy set by a multidisciplinary team (MDT) for patients diagnosed with esophageal cancer (EC). The effect of an MDT collaboration on patients with EC wh... (Source: BMC Cancer)
BMC Cancer
1w
Impact of pre-OP independence in patients with limited brain metastases on long-term survival
Brain metastasis represents a major complication with a significantly shorter overall survival of many oncological diseases, in particular of lung cancer, breast cancer and malignant melanoma patients. However... (Source: BMC Cancer)
BMC Cancer
1w
Prognosis prediction model based on competing endogenous RNAs for recurrence of colon adenocarcinoma
Colon adenocarcinoma (COAD) patients who develop recurrence have poor prognosis. Our study aimed to establish effective prognosis prediction model based on competing endogenous RNAs (ceRNAs) for recurrence of ... (Source: BMC Cancer)
BMC Cancer
1w
Risk of HPV-related extra-cervical cancers in women treated for cervical intraepithelial neoplasia
The aim was to estimate the risk of subsequent extra-cervical Human Papillomavirus (HPV) related cancer in patients surgically treated for high grade cervical intraepithelial neoplasia (CIN 2 –3). This is the f... (Source: BMC Cancer)
BMC Cancer
1w
Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer
New treatment options for ovarian cancer are urgently required. Tumor-associated macrophages (TAMs) are an attractive target for therapy; repolarizing TAMs from M2 (pro-tumor) to M1 (anti-tumor) phenotypes rep... (Source: BMC Cancer)
BMC Cancer
1w
Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the leading cause of primary liver cancers. Surveillance of individuals at specific risk of developing HCC, early diagnostic markers, and new therapeutic approaches are essent... (Source: BMC Cancer)
BMC Cancer
1w
Modelling the lifetime cost-effectiveness of radical prostatectomy, radiotherapy and active monitoring for men with clinically localised prostate cancer from median 10-year outcomes in the ProtecT randomised trial
Optimal management strategies for clinically localised prostate cancer are debated. Using median 10-year data from the largest randomised controlled trial to date (ProtecT), the lifetime cost-effectiveness of ... (Source: BMC Cancer)
BMC Cancer
1w
NFAT2 overexpression suppresses the malignancy of hepatocellular carcinoma through inducing Egr2 expression
In this study, we aimed to explore the effect of NFAT2 expression on cell fate of HepG2... (Source: BMC Cancer)
BMC Cancer
1w
A phase II study of daily carboplatin plus irradiation followed by durvalumab for stage III non-small cell lung cancer patients with PS 2 up to 74  years old and patients with PS 0 or 1 from 75 years: NEJ039A (trial in progress)
Durvalumab is a standard drug used during maintenance therapy after chemoradiotherapy in patients with locally advanced non-small cell lung cancer (LA-NSCLC). However, little is known about the clinical benefi... (Source: BMC Cancer)
BMC Cancer
1w
Clinical characteristics and blood/serum bound prognostic biomarkers in advanced pancreatic cancer treated with gemcitabine and nab-paclitaxel
In recent years treatment options for advanced pancreatic cancer have markedly improved, and a combination regimen of gemcitabine and nab-paclitaxel is now considered standard of care in Sweden and elsewhere. ... (Source: BMC Cancer)
BMC Cancer
1w
Application of ultrasound artificial intelligence in the differential diagnosis between benign and malignant breast lesions of BI-RADS 4A
The classification of Breast Imaging Reporting and Data System 4A (BI-RADS 4A) lesions is mostly based on the personal experience of doctors and lacks specific and clear classification standards. The developme... (Source: BMC Cancer)
BMC Cancer
1w
Genetic diagnostic features after failure of initial treatment with epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors among non-small-cell lung cancer patients harboring EGFR mutations
Osimertinib, a third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI), can be used as second-line treatment for lung cancer patients harboring the T790M substitution. Although... (Source: BMC Cancer)
BMC Cancer
1w
The psychosocial determinants of quality of life in breast cancer survivors: a scoping review
Breast cancer care today involves state-of-the-art biomedical treatment but can fail to address the broader psychosocial and quality-of-life (QoL) issues associated with the transition to breast cancer survivo... (Source: BMC Cancer)
BMC Cancer
1w
In vivo optical cellular diagnosis for uterine cervical or vaginal intraepithelial neoplasia using flexible gastrointestinal endocytoscopy -a prospective pilot study-
For patients with any kind of atypical squamous intraepithelial lesion of the uterine cervix or vagina, colposcopy and punch biopsy are common procedures for histological determination following cytology. Howe... (Source: BMC Cancer)
BMC Cancer
1w
Targeted next-generation sequencing assays using triplet samples of normal breast tissue, primary breast cancer, and recurrent/metastatic lesions
Next-generation sequencing (NGS) has shown that recurrent/metastatic breast cancer lesions may have additional genetic changes compared with the primary tumor. These additional changes may be related to tumor ... (Source: BMC Cancer)
BMC Cancer
1w
Tumor quiescence: elevating SOX2 in diverse tumor cell types downregulates a broad spectrum of the cell cycle machinery and inhibits tumor growth
Quiescent tumor cells pose a major clinical challenge due to their ability to resist conventional chemotherapies and to drive tumor recurrence. Understanding the molecular mechanisms that promote quiescence of... (Source: BMC Cancer)
BMC Cancer
1w
Simple calculation using anatomical features on pre-treatment verification CT for bladder volume estimation during radiation therapy for rectal cancer
Despite detailed instruction for full bladder, patients are unable to maintain consistent bladder filling during a 5-week pelvic radiation therapy (RT) course. We investigated the best bladder volume estimatio... (Source: BMC Cancer)
BMC Cancer
1w
Clinical outcomes of chemotherapy in patients with undifferentiated carcinoma of the pancreas: a retrospective multicenter cohort study
Undifferentiated carcinoma (UC) of the pancreas is a rare subtype of pancreatic cancer. Although UC has been considered a highly aggressive malignancy, no clinical studies have addressed the efficacy of chemot... (Source: BMC Cancer)
BMC Cancer
1w
Carbon ion radiotherapy as definitive treatment in non-metastasized pancreatic cancer: study protocol of the prospective phase II PACK-study
Radiotherapy is known to improve local tumor control in locally advanced pancreatic cancer (LAPC), although there is a lack of convincing data on a potential overall survival benefit of chemoradiotherapy over ... (Source: BMC Cancer)
BMC Cancer
1w
Quantifying the under-estimation of cervical Cancer in remote regions of Tanzania
Cervical cancer is the most common cancer among women in Sub-Saharan countries, including Tanzania. While early detection and diagnosis are available in some parts of this large country, radiotherapy has been ... (Source: BMC Cancer)
BMC Cancer
1w
Immunological and clinicopathological characteristics of C1RL in 2120 glioma patients
Glioma is a deadly and immunosuppressive brain tumour. Complement C1r subcomponent like (C1RL), a prognostic biomarker in several kinds of tumours, has attracted increasing attention from oncologists. However, th... (Source: BMC Cancer)
BMC Cancer
1w
Establishment and verification of the nomogram that predicts the 3-year recurrence risk of epithelial ovarian carcinoma
As we all know, patients with epithelial ovarian carcinoma have poor prognosis and high recurrence rate. It is critical and challenging to screen out the patients with high risk of recurrence. At present, ther... (Source: BMC Cancer)
BMC Cancer
1w
Distinctive roles of syntaxin binding protein 4 and its action target, TP63, in lung squamous cell carcinoma: a theranostic study for the precision medicine
Lung squamous cell carcinoma (LSCC) remains a challenging disease to treat, and further improvements in prognosis are dependent upon the identification of LSCC-specific therapeutic biomarkers and/or targets. W... (Source: BMC Cancer)
BMC Cancer
1w
Clinicopathological features of breast cancer patients with internal mammary and/or supraclavicular lymph node recurrence without distant metastasis
Internal mammary and/or supraclavicular (IM –SC) lymph node (LN) recurrence without distant metastasis (DM) in patients with breast cancer is rare, and there have been few reports on its clinical outcomes. (Source: BMC Cancer)
BMC Cancer
1w
Relationship of possible biomarkers with malignancy of thymic tumors: a meta-analysis
Role of biomarkers for promotion of tumor proliferation (BPTPs) and for promotion of apoptosis (BPAs) in thymic malignant tumors is still unclear. The purpose of this study was to evaluate the relationship bet... (Source: BMC Cancer)
BMC Cancer
1w
Efficacy of breast MRI for surgical decision in patients with breast cancer: ductal carcinoma in situ versus invasive ductal carcinoma
This study aimed to determ... (Source: BMC Cancer)
BMC Cancer
1w
HOXD-AS1 facilitates cell migration and invasion as an oncogenic lncRNA by competitively binding to miR-877-3p and upregulating FGF2 in human cervical cancer
Long non-coding RNAs (LncRNAs) are dysregulated in multiple human cancers and they are highly involved in tumor progression. Previous studies have identified the oncogenic lncRNA HOXD cluster antisense RNA 1 (... (Source: BMC Cancer)
BMC Cancer
1w
A high neutrophil-to-lymphocyte ratio is a poor prognostic factor for castration-resistant prostate cancer patients who undergo abiraterone acetate or enzalutamide treatment
Inflammatory cytokine markers, including the neutrophil-to-lymphocyte ratio (NLR), monocyte-lymphocyte ratio, and platelet-to-lymphocyte ratio, play important roles as prognostic markers in several solid malig... (Source: BMC Cancer)
BMC Cancer
1w
Cohort profile: King ’s Health Partners bladder cancer biobank
Bladder cancer (BC) is the 9th most common cancer worldwide, but little progress has been made in improving patient outcomes over the last 25  years. The King’s Health Partners (KHP) BC biobank was established ... (Source: BMC Cancer)
BMC Cancer
1w
Development of the SPARK family member web pages to improve symptom management for pediatric patients receiving cancer treatments
Supportive care Prioritization, Assessment and Recommendations for Kids (SPARK) is a web-based application that facilitates symptom screening and access to supportive care clinical practice guidelines (CPGs) f... (Source: BMC Cancer)
BMC Cancer
1w
Neutrophil-to-lymphocyte ratio is a prognostic factor for colon cancer: a propensity score analysis
A large number of patients suffer recurrence after curative resection, and mortality from colon cancer remains high. The role of systemic inflammatory response, as reflected by neutrophil-to-lymphocyte ratio (... (Source: BMC Cancer)
BMC Cancer
1w
The association between HPV gene expression, inflammatory agents and cellular genes involved in EMT in lung cancer tissue
Lung cancer is a leading cause of cancer morbidity and mortality worldwide. Several studies have suggested that Human papillomavirus (HPV) infection is an important risk factor in the development of lung cance... (Source: BMC Cancer)
BMC Cancer
1w
Upregulation of long non-coding RNA LOC284454 may serve as a new serum diagnostic biomarker for head and neck cancers
Identification of effective diagnostic and prognostic biomarkers of cancer is necessary for improving precision medicine. Long non-coding RNAs (lncRNAs) play an important regulatory role in tumor initiation an... (Source: BMC Cancer)
BMC Cancer
1w
HLA-DPA1 gene is a potential predictor with prognostic values in multiple myeloma
Multiple myeloma (MM) is an incurable hematological tumor, which is closely related to hypoxic bone marrow microenvironment. However, the underlying mechanisms are still far from fully understood. We took inte... (Source: BMC Cancer)
BMC Cancer
1w
Tobacco exposure as a major modifier of oncologic outcomes in human papillomavirus (HPV) associated oropharyngeal squamous cell carcinoma
The incidence of oropharyngeal squamous cell carcinoma (OPSCC) in the US is rapidly increasing, driven largely by the epidemic of human papillomavirus (HPV)-mediated OPSCC. Although survival for patients with ... (Source: BMC Cancer)
BMC Cancer
1w
GLUT-1 as a predictor of worse prognosis in pancreatic adenocarcinoma: immunohistochemistry study showing the correlation between expression and survival
Various parameters have been considered for predicting survival in pancreatic ductal adenocarcinoma. Information about western population is missing. The aim of this study is to assess the association between ... (Source: BMC Cancer)
BMC Cancer
1w
Defining the optimal bilirubin level before hepatectomy for hilar cholangiocarcinoma
In the management of operable hilar cholangiocarcinoma (HC) patients with hyperbilirubinemia, preoperative biliary drainage is a measure to bring down the bilirubin to a certain level so as to avoid adverse po... (Source: BMC Cancer)
BMC Cancer
1w
Interferon-beta enhances sensitivity to gemcitabine in pancreatic cancer
Adjuvant gemcitabine for pancreatic cancer has limited efficacy in the clinical setting. Impaired drug metabolism is associated with treatment resistance. We aimed to evaluate the chemosensitising effect of in... (Source: BMC Cancer)
BMC Cancer
1w
High platelet-to-lymphocyte ratio is associated with poor prognosis in patients with unresectable intrahepatic cholangiocarcinoma receiving gemcitabine plus cisplatin
Several systemic inflammatory response (SIR) markers, including platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and albumin-to-globulin ratio (AGR)... (Source: BMC Cancer)
BMC Cancer
1w
Correlation between peripheral blood neutrophil-lymphocyte ratio and CD34 expression in prostate cancer
The association of neutrophil-lymphocyte ratio (NLR) and CD34 expression level with PSA level, Gleason score, and clinical stage was investigated in patients with prostate cancer. The correlation between NLR a... (Source: BMC Cancer)
BMC Cancer
1w
A multicenter prospective phase III clinical randomized study of simultaneous integrated boost intensity-modulated radiotherapy with or without concurrent chemotherapy in patients with esophageal cancer: 3JECROG P-02 study protocol
Since the development of three-dimensional conformal radiotherapy and intensity-modulated radiotherapy (IMRT), no prospective study has investigated whether concurrent chemoradiotherapy (SIB-IMRT with 60  Gy) r... (Source: BMC Cancer)
BMC Cancer
1w
Identification of an alternative splicing signature as an independent factor in colon cancer
Colon cancer is a common malignant tumor with a poor prognosis. Abnormal alternative splicing (AS) events played a part in the occurrence and metastasis of the tumor. We aimed to develop a survival-associated ... (Source: BMC Cancer)
BMC Cancer
1w
World Health Organization grading classification for pancreatic neuroendocrine neoplasms: a comprehensive analysis from a large Chinese institution
Pancreatic neuroendocrine neoplasms (p-NENs) are a group of highly heterogeneous tumors with distinct clinicopathological features and long-term prognosis. In 2017, in order to better stratify patients into pr... (Source: BMC Cancer)
BMC Cancer
1w
A pilot study of improved psychological distress with art therapy in patients with cancer undergoing chemotherapy
Art therapy may improve the physical, mental, and emotional wellbeing of individuals for a variety of purposes. It remains understudied and underutilized in cancer care. We sought to determine the ability of a... (Source: BMC Cancer)
BMC Cancer
1w
Identifying metrics of success for transitional care practices in childhood cancer survivorship: a qualitative interview study of survivors
Adolescent and young adult (AYA) childhood cancer survivors (CCS) should be empowered to continue their survivor-focused care as they transition into adult medicine. However, the majority of AYA-aged survivors... (Source: BMC Cancer)
BMC Cancer
1w
The interaction between TERT promoter mutation and MGMT promoter methylation on overall survival of glioma patients: a meta-analysis
There are controversial results concerning the prognostic implication of TERT promoter mutation in glioma patients concerning MGMT status. In this meta-analysis, we investigated whether there are any interactions... (Source: BMC Cancer)
BMC Cancer
1w
Survival outcomes in men with a positive family history of prostate cancer: a registry based study
To investigate the correlation between family history of prostate cancer (PCa) and survival (overall and cancer specific) in patients undergoing treatment for PCa. (Source: BMC Cancer)
BMC Cancer
1w
FUT4siRNA augments the chemosensitivity of non-small cell lung cancer to cisplatin through activation of FOXO1-induced apoptosis
Increased fucosylation is associated with the chemoresistance phenotype. Meanwhile, fucosyltransferase IV (FUT4) amounts are frequently elevated in lung cancer and may be related to increased chemoresistance. (Source: BMC Cancer)
BMC Cancer
1w
Anti-cancer agent 3-bromopyruvate reduces growth of MPNST and inhibits metabolic pathways in a representative in-vitro model
Anticancer compound 3-bromopyruvate (3-BrPA) suppresses cancer cell growth via targeting glycolytic and mitochondrial metabolism. The malignant peripheral nerve sheath tumor (MPNST), a very aggressive, therapy... (Source: BMC Cancer)
BMC Cancer
1w
ALDH-1-positive cells exhibited a radioresistant phenotype that was enhanced with hypoxia in cervical cancer
We have previously found there was a small subpopulation of cells with cancer stem cell-like phenotype ALDH-1 in cervical cancer. Radiotherapy has been applied in most of the cervical cancer. However,the mecha... (Source: BMC Cancer)
BMC Cancer
1w
Relationship between the invasion of lymphocytes and cytokines in the tumor microenvironment and the interval after single brachytherapy hypofractionated radiotherapy and conventional fractionation radiotherapy in non-small cell lung Cancer
This study aimed to analyze the relationship between the invasion of lymphocytes and cytokines in the tumor mi... (Source: BMC Cancer)
BMC Cancer
1w
Long-term all-cause mortality and its association with cardiovascular risk factors in thyroid cancer survivors: an Israeli population-based study
The global incidence of thyroid cancer (TC) has risen considerably during the last three decades, while prognosis is generally favorable. We assessed the long-term all-cause mortality in TC survivors compared ... (Source: BMC Cancer)
BMC Cancer
1w
Incidence and risk factor for short term postoperative cough after thyroidectomy
The prevalence of potential risk factors for postoperative cough after thyroidectomy remain unknown. The current study aimed to research postoperative cough in patients undergoing thyroid surgery prospectively. (Source: BMC Cancer)
BMC Cancer
1w
Nomogram for predicting the overall survival and cancer-specific survival of patients with extremity liposarcoma: a population-based study
Extremity liposarcoma represents 25% of extremity soft tissue sarcoma and has a better prognosis than liposarcoma occurring in other anatomic sites. The purpose of this study was to develop two nomograms for p... (Source: BMC Cancer)
BMC Cancer
1w
Development and validation of oral chemotherapy self-management scale
With the increase of oral chemotherapy drugs, patients receiving cancer treatment prefer oral chemotherapy versus intravenous, given equal efficacy and toxicity. However, they need to take an active part in th... (Source: BMC Cancer)
BMC Cancer
1w
Development and validation of a novel pseudogene pair-based prognostic signature for prediction of overall survival in patients with hepatocellular carcinoma
There is growing evidence that pseudogenes may serve as prognostic biomarkers in several cancers. The present study was designed to develop and validate an accurate and robust pseudogene pairs-based signature ... (Source: BMC Cancer)
BMC Cancer
1w
RACE-trial: neoadjuvant radiochemotherapy versus chemotherapy for patients with locally advanced, potentially resectable adenocarcinoma of the gastroesophageal junction - a randomized phase III joint study of the AIO, ARO and DGAV
Despite obvious advances over the last decades, locally advanced adenocarcinomas of the gastroesophageal junction (GEJ) still carry a dismal prognosis with overall 5-year survival rates of less than 50% even w... (Source: BMC Cancer)
BMC Cancer
1w
Plasma-based longitudinal mutation monitoring as a potential predictor of disease progression in subjects with adenocarcinoma in advanced non-small cell lung cancer
Identifying and tracking somatic mutations in cell-free DNA (cfDNA) by next-generation sequencing (NGS) has the potential to transform the clinical management of subjects with advanced non-small cell lung canc... (Source: BMC Cancer)
BMC Cancer
1w

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