1.
Vestn Otorinolaringol. 2019;84(5):93-97. doi: 10.17116/otorino20198405193.
[Replacement methods of the septal framework of the septoplasty].
[Article in Russian; Abstract available in Russian from the publisher]
Sergeeva NV1, Rusetsky YY2, Svistushkin VM1, Reshetov IV3, Spiranskaya OA4, Makhambetova EA5, Lipsky KB3, Sadikov IS6.
Author information
- 1
- ENT-Department Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia, 119991.
- 2
- ENT-Department Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia, 119991; Department of ENT, Federal State Autonomous Institution National Medical Research Center of Children's Health Of the Ministry of Health of the Russian Federation, Moscow, Russia, 119296.
- 3
- Department of Oncology and Reconstructive Surgery Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia, 119991.
- 4
- Department of ENT, Federal State Autonomous Institution National Medical Research Center of Children's Health Of the Ministry of Health of the Russian Federation, Moscow, Russia, 119296.
- 5
- The Department of ENT and ophthalmology of the Federation and JSC Medical University Astana, Astana, Kazakhstan, 010000.
- 6
- The Otorhinolaryngology Department Clinic 'K+31' Moscow, Russia, 119415.
Abstract
In modern rhinosurgery it is generally accepted that the framework of the nasal septum dyring septoplasty should be preserved or, if it is possible, restored. The article presents a literature review of various techniques of reinforcement and replacement of septal framework. Each of them has its own advantages and disadvantages, while universal, common technology is lacking. Analysis of the literature shows that the improvement of the replacement technique is still relevant.
KEYWORDS:
extracorporeal septoplasty; reimplantation; reinforcement; replacement of septal framework; septoplasty
2.
Vestn Otorinolaringol. 2019;84(5):89-92. doi: 10.17116/otorino20198405189.
['School of Excellence' in the structure of teaching otorhinolaryngology at the department of diseases of the ear, nose and throat of Sechenov University: experience and perspective].
[Article in Russian; Abstract available in Russian from the publisher]
Author information
- 1
- First Moscow State Medical University, Moscow, Russia 119991.
Abstract
We describe our experience of teaching practical skills in Otorhinolaryngology in the Department of Ear, Larynx and Nose diseases of the Sechenov First Moscow State Medical University (Sechenov University) as a part of the rector's project 'School of Mastery' Training is held under the program, specially designed at the department. This program takes into account all the aspects of ENT doctor's practice. During their training in the school students actively participate in the work of the ENT department - they visit the dressing room, operating theater, take part in professors' rounds, and oversee the patients with various ENT conditions. Seminars are held weekly to consolidate learned practical skills. Training sessions are also held in departments of Children's Otorhinolaryngology and emergency ENT department. Results of the 'School of Mastery' were analyzed at the Department of Ear, Larynx and Nose diseases. Future perspectives are also stated.
KEYWORDS:
School of Mastery; practical training; teaching practical skills
3.
Vestn Otorinolaringol. 2019;84(5):85-88. doi: 10.17116/otorino20198405185.
[Complications caused by hearing aid mold impression material - clinical case and literature review].
[Article in Russian; Abstract available in Russian from the publisher]
Author information
- 1
- Russian Medical Academy of Continuous Professional Education, Moscow, Russia, 125993.
Abstract
The procedure of taking an impression of the external auditory canal for the manufacture of individual earplugs in the ear canals can be associated with complications in some cases. The article describes the clinical case of ingestion of the impression mass during taking the impression of the external auditory canal in the patient with chronic otitis media. The presence of pronounced hearing loss has become the basis for the selection of a hearing aid. As a result, during taking a cast of the external auditory canal, the material fell into the middle ear cavity. Despite contacting specialists, the patient experienced earache with periodic suppuration during the year. When contacting our clinic, perforation of the tympanic membrane was detected and a CT of the temporal bones revealed a foreign body in the tympanic cavity. The patient underwent surgical treatment. The clinical case we are observing and the literature data show how important it is collect to carefullythe anamnesis and conduct otorhinolaryngological examination before the procedure for taking an impression of the external auditory canal when selecting a hearing aid.
KEYWORDS:
comlications caused by hearing aid mold impression; impression material
4.
Vestn Otorinolaringol. 2019;84(5):81-84. doi: 10.17116/otorino20198405181.
[Subcutanious emphysema and pneunomediastinum - the rare complication of tonsillectomy].
[Article in Russian; Abstract available in Russian from the publisher]
Author information
- 1
- Rostov State Medical University, Rostov-on-Don, Russia, 344022.
- 2
- City hospital #1, named after N.A. Semashko, Rostov-on-Don, Russia, 344010.
Abstract
Tonsillectomy is one of the most common surgical interventions in the practice of ENT hospitals. As a rule, complications of tonsillectomy are early and late postoperative bleeding. However, in extremely rare cases tonsillectomy can be complicated by subcutaneous emphysema and pneumomediastinum. The mechanism by which these complications develop are poorly understood. The article describes the case of a rare complication of tonsillectomy - the intraoperative development of subcutaneous emphysema and pneumomediastinum. Such complications are most likely caused by deep trauma of the pharyngobasilar fascia of the tonsillar fossa, which causes the penetration of the air into the parapharyngeal space and its subsequent spread to the mediastinum.
KEYWORDS:
pneumomediastinum; subcutaneous emphysema; tonsillectomy
5.
Vestn Otorinolaringol. 2019;84(5):76-80. doi: 10.17116/otorino20198405176.
[Primary juvenile nasal angiofibroma in a 38 year-old male (case report)].
[Article in Russian; Abstract available in Russian from the publisher]
Author information
- 1
- N.N. Burdenko National Medical Research Center for Neurosurgery, Moscow, Russia, 125047.
Abstract
Juvenile nasal angiofibroma (JNA) is a benign, fibro-vascular, locally aggressive tumor with invasive growth patterns and high probability of recurrence. JNA present exclusively in adolescent boys between 9 and 19 years of age, total about 0.05% of head and neck tumors. 143 patients with JNA had been treated surgically from 2002 to August 2018 at N.N. Burdenko National Medical Research Center for Neurosurgery. All patients (primary and recurrences) were males of the age 7-38 years (16.1 [11.3; 19] years). The age of patients with primary JNA was less than 18-year old, of the exception of presenting case. There are more and more publications about case reports and successful treatment series of JNA. However, after detailed review the literature we revealed some kind of confusion: there are case reports of JNA in women and elderly people, JNA in patients with some systemic diseases, JNA with different places of origin and different morphological structure. In this paper we present a very rare case of 38 year-old male with pure primary JNA, accidentally diagnosed on CT and pathologically proven after endoscopic removal. This case confirms the possibility of detecting the JNA in adult men and explains why proper diagnosis of angiofibromas is necessary. The unique case and the literature review are presented.
KEYWORDS:
cellular type angiofibroma; extranasopharyngeal angiofibroma; juvenile nasal angiofibroma; nasopharyngeal angiofibroma; orbital giant cell angiofibroma; tuberous sclerosis complex
6.
Vestn Otorinolaringol. 2019;84(5):73-75. doi: 10.17116/otorino20198405173.
[Two cases of bilateral lymphangiomatous palatine tonsil polyps in children].
[Article in Russian; Abstract available in Russian from the publisher]
Author information
- 1
- State Budgetary Healthcare Institution 'Morozov Child City Clinical Hospital of the Healthcare Department of Moscow', Moscow, Russia, 119049.
- 2
- State Budgetary Healthcare Institution 'Morozov Child City Clinical Hospital of the Healthcare Department of Moscow', Moscow, Russia, 119049; Otorhinolaryngology department of the pediatric department of Pirogov Russian National Research Medical University, Moscow, Russia, 117997.
- 3
- Otorhinolaryngology department of the pediatric department of Pirogov Russian National Research Medical University, Moscow, Russia, 117997.
Abstract
Lymphangiomatous polyps of palatine tonsils are a rare condition, which is diagnosed with patomorphological study. About cases in total are reported in the literature, mostly with one-sided lesions. We managed to find only two reports of lymphangiomatous polyps of palatine tonsils in the available literature. The patients were children in both cases. We report our two cases of children with lymphangiomatous polyps of palatine tonsils.
KEYWORDS:
childhood; lympangioma; lymphangiomatous polyp; palatine tonsil
7.
Vestn Otorinolaringol. 2019;84(5):68-72. doi: 10.17116/otorino20198405168.
[Peculiarities of clinical course of inflammatory diseases of the oropharynx of various etiologies and possibilities of local therapy].
[Article in Russian; Abstract available in Russian from the publisher]
Author information
- 1
- Pirogov Russian National Research Medical University, Moscow, Russia, 117997; L.I. Sverzhevsky Research Institute of Clinical Otorhinolaryngology, Moscow Health Department, Moscow, Russia, 117152.
- 2
- L.I. Sverzhevsky Research Institute of Clinical Otorhinolaryngology, Moscow Health Department, Moscow, Russia, 117152.
Abstract
The article covers the problems of diagnosis and treatment of inflammatory diseases of the oropharynx. The authors consider the main nosological forms of focal inflammation in the throat, discuss the role of β-hemolytic streptococcus group A in the genesis of angina and chronic tonsillitis and their complications. The authors discuss the influence of irritants - smoking, alcohol, cold air, gastroesofareal reflux on the development of chronic inflammation of the oropharynx mucosa. Leading clinical symptoms in oropharyngeal diseases and the main methods of their treatment are presented. The authors conclude that the most effective treatment of focal inflammation in the throat is the use of combined topical drugs. As a choice for local therapy of pharyngeal diseases, the authors offer a combined drug Doritiricin, effectively and safely relieving pain syndrome and local inflammatory response.
KEYWORDS:
Doritiricin; inflammation; local therapy; pharynx; sore throat
8.
Vestn Otorinolaringol. 2019;84(5):61-67. doi: 10.17116/otorino20198405161.
[Results of an open, randomized, actively controlled study of the efficacy and safety of the new drug Freinozole nasal spray (Phenylephrine + Cetyrizine) in patients with acute respiratory infection].
[Article in Russian; Abstract available in Russian from the publisher]
Author information
- 1
- FSBI 'St. Petersburg Research Institute of Ear, Throat, Nose and Speech' Russian Federation Ministry of Healthcare, St. Petersburg, Russia, 190013.
- 2
- Federal State Budgetary Educational Institution of Higher Education Ivanovo State Medical Academy, Ministry of Health of the Russian Federation, Ivanovo, Russia, 153012.
- 3
- State budgetary institution of health care of the Samara region 'Samara city hospital #4', Samara, Russia, 443056.
- 4
- Uromed, LLC, Smolensk, Russia, 214031.
- 5
- Medical center Probiotech LLC, Moscow, Russia, 111024.
Abstract
The aim of the study was proof of efficacy and safety of the drug Frinozol nasal spray in patients with acute respiratory infection (acute rhinitis). PATIENTS AND METHODS: A randomized open-label study with active control included 134 ambulatory patients: men and women aged 18 to 65 years with acute upper respiratory tract infection (acute rhinitis) lasting no more than 48 hours before inclusion into the study. Patients were randomized in two groups: group 1 took Frinozol nasal spray 2 sprays per each nostril three times a day for 7 days, subjects randomized to the group 2 took Vibrocil at the same dose and treatment regimen. The primary efficacy endpoint in the study was assessment of the dynamics of symptoms such as nasal congestion, rhinorrhea, itching in the nose and hyposmia using 10 cm VAS in 1 day after the start of treatment compared to the baseline. Secondary endpoints included assessment of the dynamics of nasal symptoms after 7 days of treatment, changes in the values of the Congestion Quantifier 5, CQ-5 questionnaire and evaluation of the effectiveness by the investigator. Safety analysis was carried out throughout the study and included the assessment of adverse events, laboratory data, vital signs, ECG assessment. RESULTS: According to the results of the study and comparative analysis of the primary (assessment of the dynamics of nasal symptoms on a 10 cm visual analogue scale 1 day after the start of treatment) and secondary efficacy endpoints as well as a comprehensive safety analysis, it can be concluded that the study drug is not inferior to the reference drug. Thus, the new combination Frinozol nasal spray is an effective and safe treatment for patients with acute respiratory infections.
KEYWORDS:
acute respiratory infection; cetirizine; intranasal administration; phenylephrine; randomized clinical trial
9.
Vestn Otorinolaringol. 2019;84(5):55-60. doi: 10.17116/otorino20198405155.
[Results of the observational (non-interventional) research 'Analysis of therapeutic efficiency of the polyvalent Piobacteriophag (Secstaphag) in the treatment of acute sinusitis'].
[Article in Russian; Abstract available in Russian from the publisher]
Author information
- 1
- Sverzhevsky Research Institute of Clinical Otorhinolaryngology, Moscow, Russia, 117152; Russian National Research Medical University named after N.I. Pirogov, Moscow, Russia, 117997.
- 2
- Sverzhevsky Research Institute of Clinical Otorhinolaryngology, Moscow, Russia, 117152.
Abstract
He article describes an observational (non-intervening) research 'Analysis of the therapeutic efficacy of the Polyvalent Piobacteriophage (secstafag) in the treatment of acute sinusitis'. The obtained results prove the effectiveness of the drug in the treatment of this ENT pathology.
KEYWORDS:
Pyobacteriophage Polyvalent; acute sinusitis; bacteriophages; phagotherapy; secstaphag
10.
Vestn Otorinolaringol. 2019;84(5):48-54. doi: 10.17116/otorino20198405148.
[Rhinosinusitis in Hurler syndrome patients requiring hematopoietic stem cells transplantation].
[Article in Russian; Abstract available in Russian from the publisher]
Karpishchenko SA1, Dolgov OI1, Bykova TA1, Rodneva YA1, Borovkova AS1, Ovechkina VN1, Osipova AA1, Utimisheva ES1, Moiseev IS1, Zubarovskaya LS1, Afanas'ev BV1.
Author information
- 1
- Pavlov First Saint-Petersburg State Medical University, Saint-Petersburg, Russia, 197022.
Abstract
INTRODUCTION:
Allogenic transplantation of hemopoetic stem cells (allo-THSC) is one of the most effective treatment methods for Hurler syndrome, aimed at maximal correction of complications related to the genetic disorder. Presence of infection in the recipient is an adverse risk factor, affecting the possibility of starting the conditioning regimen and THSC peforming in general.
AIM:
To assess the condition of the nasal cavity and paranasal sinuses in Hurler syndrome patients before the allo-THSC, dynamics of these changes after the transplantation taking into account the correction of alpha-L-iduronidase enzyme level with donor blood cells.
MATERIAL AND METHODS:
From February 2012 to December 2017, In the Raisa Gorbacheva Research Institute of Child Oncology, Hematology and Transplantology of the Pavlov First Saint Petersburg State Medical University, eighteen Hurler syndrome patients (10 girls and 8 boys) received an allo-THSC. Median age at the time of the procedure was 23,5 months (min - 3,4; max - 24,8). Each patient with the shadowing of paranasal sinuses, rhinitis or nasal breathing difficulty received a standard rhinosinusitis treatment before the transplantation, effect of which was insignificant. Symptoms of rhinitis, condition of pharyngeal tonsil and paranasal sinuses were assessed before and auto the allo-THSC.
RESULTS:
In the post-allo-THSC, with the correction of alpha-L-iduronidase level each evaluated parameter has improved reliably (p-value < 0,05). Comparative analysis of the condition of the nasal cavity and pharyngeal tonsil before and after THSC was conducted on 14 patients out of 18. Rhinitis symptoms decreased in 9 (64,2%) patients; in 11 patients (78,5%) adenoids size reduced. Comparative analysis of the condition of paranasal sinuses was possible in 12 patients out of 18. Sinuses aeration improved in eight (66,6%) if patients.
CONCLUSION:
Nasal cavity and paranasal sinuses changes in Hurler syndrome patients before and after allo-THSC is poorly studied. Our experience demonstrates the normalization of nasal cavity, pharyngeal tonsila and paranasal sinuses symptoms in the majority of the patients receiving allo-THSC. These symptoms are, it seems a consequence of the underlying disease.
KEYWORDS:
Hurler; haemopoietic stem cell transplantation; mucopolysaccharidosis; sinusitis
11.
Vestn Otorinolaringol. 2019;84(5):44-47. doi: 10.17116/otorino20198405144.
[Experience of the interdisciplinary approach to diagnostics and treatment of patients with bisphosphonate osteonecrosis of the upper jaw].
[Article in Russian; Abstract available in Russian from the publisher]
Author information
- 1
- FSBEI HE 'RNIU them N.I. Pirogov, Ministry of Health of the Russian Federation, Department of Maxillofacial Surgery and Dentistry, Faculty of Dentistry, Moscow, Russia, 117997.
- 2
- FSBEI HE 'RNIU them. N.I. Pirogov, Ministry of Health of Russia, Department of Otolaryngology named after Academician B.S. Preobrazhensky Medical Faculty, Moscow, Russia, 117997.
Abstract
The article discusses the issues of diagnosis, the clinical course of osteonecrosis of the upper jaw in patients with oncological diseases. The assessment of radiological indicators of bone pathology of the upper jaw, signs of the development of the inflammatory process of the maxillary sinus and other sinuses of the nose. The experience of conservative tactics and surgical treatment of patients in this group is analyzed with the participation of specialists from otorhinolaryngologists and maxillofacial surgeons.
KEYWORDS:
bis-phonon preparations; maxillary sinusitis; oncological diseases; osteonecrosis
12.
Vestn Otorinolaringol. 2019;84(5):38-43. doi: 10.17116/otorino20198405138.
[Evaluation the velocity of vocal fold movements in adults by duplex Doppler scanning].
[Article in Russian; Abstract available in Russian from the publisher]
Author information
- 1
- Irkutsk state Medical University, Irkutsk, Russia, 664025.
Abstract
AIM:
To evaluate the velocity of vocal fold movements by duplex Doppler scanning in adults during breathing, talking and phonation.
METHODS:
Twenty healthy volunteers (18 women and 2 men) without of voice problems were investigated with scanners Logic-7 or Aloka 1100 by the linear transducer 7-10 MHz. The thyroid cartilage was used as an acoustic window. The dependence between the vocal fold velocity and volume and pitch of the voice were estimated using Spearman correlation.
RESULTS:
The velocity of movements of the vocal folds during breathing was from 5 to 16 cm/s, during talking and phonation - from 9 to 110 cm/s. Coefficient of Spearman correlation between the voice pitch and the vocal fold velocity was +0.9±0.1 an average, between volume of the voice and the vocal fold velocity was - 0.7±0.1.
CONCLUSION:
Duplex Doppler ultrasound scanning of the larynx allows measuring the velocity of vocal fold's movements during breathing, conversation and phonation. The fold's velocity increases with increasing of the voice volume and decreases with increasing the voice pitch. Duplex Doppler ultrasound scanning may be useful for early detection of disorders of mobility of the vocal folds.
KEYWORDS:
duplex Doppler ultrasound scanning of the larynx; phonation investigation; ultrasonography of the larynx; vocal fold velocity
13.
Vestn Otorinolaringol. 2019;84(5):32-37. doi: 10.17116/otorino20198405132.
[Surgical interventions on the pharynx in the structure of otorhinolaryngological care to the population of the city of Moscow].
[Article in Russian; Abstract available in Russian from the publisher]
Kryukov AI1, Tsarapkin GY2, Ivoylov AY2, Tovmasyan AS2, Artemyeva-Karelova AV2, Kirasirova EA2, Polyaeva MY2, Kishinevskii AE2.
Author information
- 1
- The Sverzhevskiy's Otorhinolaryngology Healthcare Research Institute, Moscow, Russia, 117152; Department of otorhinolaryngology medical faculty of Russian National Research Medical University n.a. N.I. Pirogov, Moscow, Russia, 117997.
- 2
- The Sverzhevskiy's Otorhinolaryngology Healthcare Research Institute, Moscow, Russia, 117152.
Abstract
The authors studied the reporting documentation of otorhinolaryngological hospitals of the city of Moscow on the surgical treatment of pharyngeal pathology in adults from 2002 to 2017. It was found that for 16 years surgical treatment of 290 362 patients with ENT-diseases was performed: 181.206 (62.4%) patients with diseases of the nose and paranasal sinuses, 24.981 (8.6%) patients with ear pathology, 60.346 (20.8%) patients with diseases of the pharynx and 23.829 (8.2%) - with diseases of the larynx. The assessment of the overall dynamics of the studied indicators was carried out on the 'trend lines'. For the considered period, the number of patients with surgical pathology of the pharynx increased by 33.2%. The proportion of tonsillectomies increased by 1.85 times to 56.5%, drainage of peritonsillar abscesses and abscesses-tonsillectomies decreased by 19%, uvulopalatoplastic increased 4.1 times, removal of neoplasms of the pharynx increased 2.2 times, adenotomies decreased by 2.4 times. Analysis of the data allowed to establish that, against the background of an ever-increasing number of surgical interventions for diseases of the pharynx in adults, a descending trend was noted only in the treatment of complicated forms of chronic tonsillitis and hypertrophy of the pharyngeal tonsil.
KEYWORDS:
chronic tonsillitis; peritonsillar abscess; pharyngeal diseases; pharyngeal neoplasm; pharyngeal tonsil hypertrophy; snoring; trendline
14.
Vestn Otorinolaringol. 2019;84(5):26-31. doi: 10.17116/otorino20198405126.
[General anesthesia influence on cochlear implant intraoperative testing].
[Article in Russian; Abstract available in Russian from the publisher]
Kalugina MS1, Rusetskiy YY1, Aleksandrov AE1, Alekseeva EA1, Pashkov AV1, Gadaleva SV2, Arutyunyan SK1.
Author information
- 1
- Federal State Autonomous Institution 'National Medical Research Center Of Children's Health' Of Ministry Of Healthcare Of Russia, Moscow, Russia, 119991.
- 2
- Sechenov First Moscow State Medical University Of Ministry Of Healthcare Of Russia, Moscow, Russia, 119991.
Abstract
In this article, we consider the influence of combined general anesthesia on the results of electrically-involved stapedial reflex threshold (esrt) registration. We pay a special attention to the anesthesia to exclude its influence on the esrt. This study included 52 patients with bilateral chronic neurosensory hearing impairment. We conducted a retrospective (from 2014 to 2016) and prospective (from 2017 to 2018) analysis of anesthesia protocols. Even though the inhaled anesthesia (sevoflurane in this case) has a depressive effect on esrt registration (the higher the minimal alveolar concentration of anesthetic agent, the higher the reflex threshold), our study shows a possibility of using it in an extended anesthesia monitoring. Inclusion of myorelaxants in cochlear implantation anesthesia protocol not only provides a safe anesthesia, but also does not prevent a timely intraoperative cochlear implant testing.
KEYWORDS:
cochlear implantation; general anesthesia; pediatrics; stapedial reflex
15.
Vestn Otorinolaringol. 2019;84(5):20-25. doi: 10.17116/otorino20198405120.
[Variants of treatment of the head direction at the festulars of the labi-rint of inflammatory genesis].
[Article in Russian; Abstract available in Russian from the publisher]
Kryukov AI1, Kynelskaya NL1, Garov EV1, Zelikovich EI1, Baybakova EV1, Zelenkova VN1, Garova EE1, Martirosyan TG1.
Author information
- 1
- Sverzhevskiy's Otorhinolaryngology Healthcare Research Institute, Moscow, Russia, 117152.
Abstract
PURPOSE:
To analyze the effectiveness of various methods of treating dizziness with fistulas of the labyrinth (FL) of inflammatory genesis. An analysis of the surgical treatment of 216 patients with chronic suppurative otitis media (CSOM) with cholesteatoma complicated by FL using a variety of FL treatment methods is presented. All patients underwent a debridement operation on the middle ear or revision of the postoperative cavity: in 48 patients with a matrix of cholesteatoma in situ on the fistula, in 109 patients with matrix removal followed by plastic repair or FL filling with various autotissues, in 59 patients with matrix conservation, plastic removal or filling FL and SLD labyrinth. In the last two groups, filling of a semicircular canal (SC) defect was performed in 33 patients, and mastoidoplasty - in 47.
CONCLUSION:
All used FL treatment techniques are effective in the treatment of peripheral vestibular disorders. Careful treatment of SC fistula after removal of all pathological conditions in the absence of active inflammation and the appointment of hormone therapy in the postoperative period are the main factors in preserving the functions of the labyrinth in any surgical technique. Filling of the lumen of the SC and mastoidoplasty in patients with CSOM with FL can eliminate peripheral dizziness.
KEYWORDS:
cholesteatoma; chronic suppurative otitis media; labyrinth fistula; surgical treatment
16.
Vestn Otorinolaringol. 2019;84(5):15-19. doi: 10.17116/otorino20198405115.
[Key points of 'Noise-induced hearing loss' clinical guidelines].
[Article in Russian; Abstract available in Russian from the publisher]
Author information
- 1
- FSBI Otorhinolaryngology Clinical Research Center of the FMBA, Moscow, Russia, 123182.
- 2
- FGBNU Research Institute of Occupational Medicine them Academician N.F. Izmerov, Moscow, Russia, 105118.
- 3
- FSBI Russian Scientific and Clinical Center for Audiology and Hearing Aid, FMBA.
- 4
- Moscow, Russia, 117513.
- 5
- Federal state unitary enterprise All-Russian research Institute of railway hygiene of Rospotrebnadzor, Moscow, Russia, 125497 ,FBE of Science Federal Scientific Center of Hygiene named after F.F. Erisman of Rospotrebnadzor, Mytischi, Moscow region, Russia, 141014.
Abstract
In this article we present the key points of 'Noise-induced hearing loss' clinical guidelines, which are included to the Clinical Guidelines Classifier of the Ministry of Health of Russia (2018). We give the definition of 'Noise-induced hearing loss', disclose the main causes and pathogenetic features of hearing impairment in employees who are affected by intensive noise at work. We state the main clinical and diagnostic criteria, treatment and rehabilitation principles; present the basics of primary and secondary prevention of hearing impairment in 'noise-hazardous' workers. We also disclose in detail the algorithm of expertise of hearing diseases connection with the profession on the stages of preliminary and final professional disease. Professional suitability issues are also discussed. Clinical guidelines contain a unified classification of noise-induced hearing loss severity complied with international approaches and medical and social expertise criteria.
KEYWORDS:
algorithm of expertise of connection with profession; clinical and diagnostic criteria; noise-induced hearing loss; treatment and rehabilitation treatment
17.
Vestn Otorinolaringol. 2019;84(5):6-14. doi: 10.17116/otorino2019840516.
[Topical drug administration to the inner ear. Modern state of the problem and development perspectives].
[Article in Russian; Abstract available in Russian from the publisher]
Kryukov AI1, Kunelskaya NL1, Shershunova EA2, Rebrov IE2, Yamshchikov VA2, Garov EV1, Tsarapkin GY1, Mishchenko VV1.
Author information
- 1
- The Sverzhevskiy's Otorhinolaryngology Healthcare Research Institute, Moscow, Russia, 117152.
- 2
- The Institute for Electrophysics and Electric Power of the Russian Academy of Sciences, Sanct-Petersburg, Russia, 191186.
Abstract
The work assessed modern methods of drug delivery through biological barriers to the lesion, in particular, through the most studied - skin. The main advantages and disadvantages of the existing methods for the topical administration of drugs into the inner ear - intra-imperial and intra-labyrinth delivery are analyzed. A brief review of medicinal substances for topical administration to the inner ear, both widely used (for example, aminoglycosides, steroid drugs) and undergoing clinical trials, is given. An assessment is made of the prospects for the use of transmembrane drug delivery to the inner ear using an electric field, which has a combined electro-creative and iontophoretic effect.
KEYWORDS:
Meniere’s disease; cochleovestibular disorders; electroporation; inner ear; neurosensory hearing loss; phonoelectrophoresis; translabirint drug delivery
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