Atmosphere, Vol. 10, Pages 750: Growth Rate of Gravity Wave Amplitudes Observed in Sodium Lidar Density Profiles and Nightglow Image Data Atmosphere doi: 10.3390/atmos10120750 Authors: Fabio Vargas Guotao Yang Paulo Batista Delano Gobbi Amplitude growth rates of quasi-monochromatic gravity waves were estimated and compared from multiple instrument measurements carried out in Brazil. Gravity wave parameters, such as the wave amplitude and growth rate in distinct altitudes, were...
Atmosphere, Vol. 10, Pages 749: Study of Galactic Cosmic-Ray Flux Modulation by Interplanetary Plasma Structures for the Evaluation of Space Instrument Performance and Space Weather Science Investigations Atmosphere doi: 10.3390/atmos10120749 Authors: Catia Grimani Daniele Telloni Simone Benella Andrea Cesarini Michele Fabi Mattia Villani The role of high-energy particles in limiting the performance of on-board instruments was studied for the European Space Agency (ESA)...
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Behavioral Sciences, Vol. 9, Pages 133: The Problem of Psychological Rehabilitation of Persons with Disorders of the Musculoskeletal System Acquired in Adulthood Behavioral Sciences doi: 10.3390/bs9120133 Authors: Tatyana Razuvaeva Yuliya Gut Anna Lokteva Evgeniya Pchelkina The problem of improving the quality of life of people with lesions of the musculoskeletal system is relevant to modern society. However, the circumstances of disabled people in modern Russia are characterized...
Behavioral Sciences, Vol. 9, Pages 132: Synchronization of Independent Neural Ensembles in Human EEG during Choice Tasks Behavioral Sciences doi: 10.3390/bs9120132 Authors: Alexander Zaleshin Galina Merzhanova During behavioral experiments, humans placed in a situation of having to choose between a more valuable but risky reward and a less valuable but guaranteed reward make their decisions in accordance with external situational factors and individual characteristics, such as inclination...
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Beverages, Vol. 5, Pages 67: Precision of a Small Brew House by Determining the Repeatability of Different Brews to Guarantee the Product Stability of the Beer Beverages doi: 10.3390/beverages5040067 Authors: Nele Bastgen Michel Ginzel Jean Titze The most important success factors of a brewery are to brew a high-standard beer and to sell this product successfully on the market. Especially, guaranteeing an objective product quality is a difficult task, in terms of beer quality,...
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Bioengineering, Vol. 6, Pages 108: Biomedical Processing of Polyhydroxyalkanoates Bioengineering doi: 10.3390/bioengineering6040108 Authors: Dario Puppi Gianni Pecorini Federica Chiellini The rapidly growing interest on polyhydroxyalkanoates (PHA) processing for biomedical purposes is justified by the unique combinations of characteristics of this class of polymers in terms of biocompatibility, biodegradability, processing properties, and mechanical behavior, as well as by their...
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Biology, Vol. 8, Pages 91: Selection of Lactic Acid Bacteria (LAB) Antagonizing Vibrio Parahaemolyticus: The Pathogen of Acute Hepatopancreatic Necrosis Disease (AHPND) in Whiteleg Shrimp (Penaeus Vannamei) Biology doi: 10.3390/biology8040091 Authors: Truc Ngoc Hong Thanh Kim Kim Truong Quoc Ngoc Acute hepatopancreatic necrosis disease (AHPND) has recently emerged as a serious disease of cultured shrimp. A total of 19 lactic acid bacteria (LAB) strains...
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Biomedicines, Vol. 7, Pages 94: Stem Cell Surgery and Growth Factors in Retinitis Pigmentosa Patients: Pilot Study after Literature Review Biomedicines doi: 10.3390/biomedicines7040094 Authors: Paolo Giuseppe Limoli Enzo Maria Vingolo Celeste Limoli Marcella Nebbioso To evaluate whether grafting of autologous mesenchymal cells, adipose-derived stem cells, and platelet-rich plasma into the supracoroideal space by surgical treatment with the Limoli retinal restoration technique...
Biomedicines, Vol. 7, Pages 93: Intracellular Localization in Zebrafish Muscle and Conserved Sequence Features Suggest Roles for Gelatinase A Moonlighting in Sarcomere Maintenance Biomedicines doi: 10.3390/biomedicines7040093 Authors: Fallata Wyatt Levesque Dufour Overall Crawford Gelatinase A (Mmp2 in zebrafish) is a well-characterized effector of extracellular matrix remodeling, extracellular signaling, and along with other matrix metalloproteinases (MMPs) and...
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Biomolecules, Vol. 9, Pages 811: Mesenchymal Stem Cell Therapy for Spinal Cord Contusion: A Comparative Study on Small and Large Animal Models Biomolecules doi: 10.3390/biom9120811 Authors: Mukhamedshina Shulman Ogurcov Kostennikov Zakirova Akhmetzyanova Rogozhin Masgutova James Masgutov Lavrov Rizvanov Here, we provide a first comparative study of the therapeutic potential of allogeneic mesenchymal stem cells derived from bone marrow (BM-MSCs),...
Biomolecules, Vol. 9, Pages 810: Deregulation of the Histone Lysine-Specific Demethylase 1 Is Involved in Human Hepatocellular Carcinoma Biomolecules doi: 10.3390/biom9120810 Authors: Kim Bolatkan Kaneko Ikawa Asada Komatsu Hayami Ojima Abe Yamaue Hamamoto Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and is a leading cause of cancer-related death worldwide. Given that the standard-of-care for advanced liver cancer...
Biomolecules, Vol. 9, Pages 809: Macromolecule Particle Picking and Segmentation of a KLH Database by Unsupervised Cryo-EM Image Processing Biomolecules doi: 10.3390/biom9120809 Authors: Miguel Carrasco Patricio Toledo Nicole D. Tischler Segmentation is one of the most important stages in the 3D reconstruction of macromolecule structures in cryo-electron microscopy. Due to the variability of macromolecules and the low signal-to-noise ratio of the structures present, there is no...
Biomolecules, Vol. 9, Pages 808: Characterization of Terpene Synthase from Tea Green Leafhopper Being Involved in Formation of Geraniol in Tea (Camellia sinensis) Leaves and Potential Effect of Geraniol on Insect-Derived Endobacteria Biomolecules doi: 10.3390/biom9120808 Authors: Ying Zhou Xiaoyu Liu Ziyin Yang When insects attack plants, insect-derived elicitors and mechanical damage induce the formation and emission of plant volatiles that have important ecological functions...
Biomolecules, Vol. 9, Pages 807: Genes Potentially Associated with Familial Hypercholesterolemia Biomolecules doi: 10.3390/biom9120807 Authors: Svetlana Mikhailova Dinara Ivanoshchuk Olga Timoshchenko Elena Shakhtshneider This review addresses the contribution of some genes to the phenotype of familial hypercholesterolemia. At present, it is known that the pathogenesis of this disease involves not only a pathological variant of low-density lipoprotein receptor and its ligands...
Biomolecules, Vol. 9, Pages 806: Chemical Constituents of the Leaves of Butterbur (Petasites japonicus) and Their Anti-Inflammatory Effects Biomolecules doi: 10.3390/biom9120806 Authors: Lee Jeong Park Ryu Lee Song Guo Choi Lee Jang Two new aryltetralin lactone lignans, petasitesins A and B were isolated from the hot water extract of the leaves of butterbur (Petasites japonicus) along with six known compounds. The chemical structures of lignans 1...
Biomolecules, Vol. 9, Pages 805: CSN5A Subunit of COP9 Signalosome Temporally Buffers Response to Heat in Arabidopsis Biomolecules doi: 10.3390/biom9120805 Authors: Singh Yadav Dhanapal Berliner Finkelshtein Chamovitz The COP9 (constitutive photomorphogenesis 9) signalosome (CSN) is an evolutionarily conserved protein complex which regulates various growth and developmental processes. However, the role of CSN during environmental stress is largely unknown. Using...
Biomolecules, Vol. 9, Pages 804: Detection and Quantification of Milk Ingredients as Hidden Allergens in Meat Products by a Novel Specific Real-Time PCR Method Biomolecules doi: 10.3390/biom9120804 Authors: Caterina Villa Joana Costa Isabel Mafra Milk ingredients are often included in a wide range of meat products, such as cooked hams and sausages, to improve technological characteristics. However, milk proteins are also important food allergens. The aim of this study was the development...
Biomolecules, Vol. 9, Pages 803: Erratum: Nepravishta, R., et al. CoCUN, a Novel Ubiquitin Binding Domain Identified in N4BP1. Biomolecules 2019, 9, 284 Biomolecules doi: 10.3390/biom9120803 Authors: Nepravishta Ferrentino Mandaliti Mattioni Weber Polo Castagnoli Cesareni Paci Santonico The Biomolecules Editorial Offices wishes to make the following erratum to this paper [...]
Biomolecules, Vol. 9, Pages 801: Cyclodextrins: Emerging Medicines of the New Millennium Biomolecules doi: 10.3390/biom9120801 Authors: Braga Cyclodextrins, since their discovery in the late 19th century, were mainly regarded as excipients. Nevertheless, developments in cyclodextrin research have shown that some of these hosts can capture and include biomolecules, highlighting fatty acids and cholesterol, which implies that they are not inert and that their action may be used in specific...
Biomolecules, Vol. 9, Pages 802: UV-Vis Spectroelectrochemistry of Oleuropein, Tyrosol, and p-Coumaric Acid Individually and in an Equimolar Combination. Differences in LC-ESI-MS2 Profiles of Oxidation Products and their Neuroprotective Properties Biomolecules doi: 10.3390/biom9120802 Authors: Lambert de Malezieu Ferron Sauvager Courtel Ramassamy Tomasi Abasq Major phenolic compounds from olive oil (ArOH-EVOO), oleuropein (Ole), tyrosol (Tyr), and p-coumaric...
Biomolecules, Vol. 9, Pages 800: Evaluation of Human Cerebrospinal Fluid Malate Dehydrogenase 1 as a Marker in Genetic Prion Disease Patients Biomolecules doi: 10.3390/biom9120800 Authors: Inga Zerr Anna Villar-Piqué Vanda Edit Schmitz Anna Poleggi Maurizio Pocchiari Raquel Sánchez-Valle Miguel Calero Olga Calero Inês Baldeiras Isabel Santana Gabor G. Kovacs Franc Llorens Matthias Schmitz The exploration of accurate diagnostic markers for differential...
Biomolecules, Vol. 9, Pages 799: Biological Activity of Thyme White Essential Oil Stabilized by Cellulose Nanocrystals Biomolecules doi: 10.3390/biom9120799 Authors: Shin Na Shin Seo Youn Park Hyun Cellulose nanocrystals (CNCs) are produced by sulfonic acid hydrolysis and used for the formation of Pickering emulsion (PE) with thyme white essential oil (EO). Highly volatile and hydrophobic thyme white is encapsulated in PE by the amphiphilicity of CNCs. Encapsulation...
Biomolecules, Vol. 9, Pages 798: Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren Biomolecules doi: 10.3390/biom9120798 Authors: Castañeda-Zegarra Huse Røsand Sarno Xing Gago-Fuentes Zhang Alirezaylavasani Werner Ji Liabakk Wang Bjørås Oksenych Classical non-homologous end joining (NHEJ) is a molecular pathway that detects, processes, and ligates DNA double-strand breaks (DSBs) throughout the cell...
Biomolecules, Vol. 9, Pages 797: Lichen Secondary Metabolite Physciosporin Decreases the Stemness Potential of Colorectal Cancer Cells Biomolecules doi: 10.3390/biom9120797 Authors: Yang Nguyen Pereira Hur Kim Secondary metabolites of lichens are promising bioresources for candidate anti-cancer drugs. Accordingly, several approaches have been proposed for screening these molecules for novel anti-cancer lead compounds. In this study, we found that a non-toxic concentration...
Biomolecules, Vol. 9, Pages 795: Apoptosis Induction of Fibroblast-Like Synoviocytes Is an Important Molecular-Mechanism for Herbal Medicine along with its Active Components in Treating Rheumatoid Arthritis Biomolecules doi: 10.3390/biom9120795 Authors: Qing Zhang Jia Liu Mengmeng Zhang Shujun Wei Ruolan Li Yongxiang Gao Wei Peng Chunjie Wu Rheumatoid arthritis (RA) is a known chronic autoimmune disease can cause joint deformity and even loss of joint function. Fibroblast-like...
Biomolecules, Vol. 9, Pages 796: Proteomic Response of Pseudomonas putida KT2440 to Dual Carbon-Phosphorus Limitation during mcl-PHAs Synthesis Biomolecules doi: 10.3390/biom9120796 Authors: Możejko-Ciesielska Serafim Pseudomonas putida KT2440, one of the best characterized pseudomonads, is a metabolically versatile producer of medium-chain-length polyhydroxyalkanoates (mcl-PHAs) that serves as a model bacterium for molecular studies. The synthesis of mcl-PHAs is of great interest...
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Brain Sciences, Vol. 9, Pages 351: Aging and Central Auditory Disinhibition: Is It a Reflection of Homeostatic Downregulation or Metabolic Vulnerability? Brain Sciences doi: 10.3390/brainsci9120351 Authors: Ibrahim Llano Aging-related changes have been identified at virtually every level of the central auditory system. One of the most common findings across these nuclei is a loss of synaptic inhibition with aging, which has been proposed to be at the heart of several aging-related...
Brain Sciences, Vol. 9, Pages 350: Estimation of Brain Functional Connectivity in Patients with Mild Cognitive Impairment Brain Sciences doi: 10.3390/brainsci9120350 Authors: Laia Farràs-Permanyer Núria Mancho-Fora Marc Montalà-Flaquer Esteve Gudayol-Ferré Geisa Bearitz Gallardo-Moreno Daniel Zarabozo-Hurtado Erwin Villuendas-González Maribel Peró-Cebollero Joan Guàrdia-Olmos Mild cognitive impairment is defined as greater cognitive decline than expected for a...
Brain Sciences, Vol. 9, Pages 349: A Meta-Analysis of Relationships between Measures of Wisconsin Card Sorting and Intelligence Brain Sciences doi: 10.3390/brainsci9120349 Authors: Kopp Maldonado Scheffels Hendel Lange The Wisconsin Card Sorting Test (WCST) represents a widely utilized neuropsychological assessment technique for executive function. This meta-analysis examined the discriminant validity of the WCST for the assessment of mental shifting, considered as an...
Brain Sciences, Vol. 9, Pages 348: Classification of Drowsiness Levels Based on a Deep Spatio-Temporal Convolutional Bidirectional LSTM Network Using Electroencephalography Signals Brain Sciences doi: 10.3390/brainsci9120348 Authors: Ji-Hoon Jeong Baek-Woon Yu Dae-Hyeok Lee Seong-Whan Lee Non-invasive brain-computer interfaces (BCI) have been developed for recognizing human mental states with high accuracy and for decoding various types of mental conditions. In particular, accurately...
Brain Sciences, Vol. 9, Pages 347: Peak Detection with Online Electroencephalography (EEG) Artifact Removal for Brain–Computer Interface (BCI) Purposes Brain Sciences doi: 10.3390/brainsci9120347 Authors: Mihaly Benda Ivan Volosyak Brain–computer interfaces (BCIs) measure brain activity and translate it to control computer programs or external devices. However, the activity generated by the BCI makes measurements for objective fatigue evaluation very difficult, and the situation...
Brain Sciences, Vol. 9, Pages 346: Higher Serum Melatonin Levels during the First Week of Malignant Middle Cerebral Artery Infarction in Non-Surviving Patients Brain Sciences doi: 10.3390/brainsci9120346 Authors: Lorente Martín Abreu-González Sabatel Ramos Argueso Solé-Violán Cáceres Jiménez García-Marín Objective: The activation of different physiopathological pathways (neuroinflammation, apoptosis, and oxidation) can lead to secondary brain injury...
Brain Sciences, Vol. 9, Pages 345: Antiplatelet versus Anticoagulation for Asymptomatic Patients with Vertebral Artery Injury during Anterior Cervical Surgery—Two Case Reports and Review of Literature Brain Sciences doi: 10.3390/brainsci9120345 Authors: Hall Cheng Cheng Danisa Vertebral Artery Injury (VAI) while performing cervical spinal reconstruction surgery is rare, but it can lead to catastrophic events. Treatment for this injury with regard to antiplatelet versus anticoagulation...
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Cancers, Vol. 11, Pages 1911: Immunological Effects of Epigenetic Modifiers Cancers doi: 10.3390/cancers11121911 Authors: Bezu Chuang Liu Kroemer Kepp Epigenetic alterations are associated with major pathologies including cancer. Epigenetic dysregulation, such as aberrant histone acetylation, altered DNA methylation, or modified chromatin organization, contribute to oncogenesis by inactivating tumor suppressor genes and activating oncogenic pathways. Targeting epigenetic...
Cancers, Vol. 11, Pages 1915: Retinoic Acid Receptors in Acute Myeloid Leukemia Therapy Cancers doi: 10.3390/cancers11121915 Authors: Martino Welch Retinoic acid (RA) signaling pathways regulate fundamental biological processes, such as cell proliferation, development, differentiation, and apoptosis. Retinoid receptors (RARs and RXRs) are ligand-dependent transcription factors. All-trans retinoic acid (ATRA) is the principal endogenous ligand for the retinoic acid receptor alpha...
Cancers, Vol. 11, Pages 1910: Spatial EGFR Dynamics and Metastatic Phenotypes Modulated by Upregulated EphB2 and Src Pathways in Advanced Prostate Cancer Cancers doi: 10.3390/cancers11121910 Authors: Liu Horning Lieberman Kim Lin Hung Chou Wang Lin Kirma Liss Vasisht Perillo Blocher Horng Taverna Ruan Yankeelov Dunn Huang Yeh Chen Advanced prostate cancer is a very heterogeneous disease reflecting in...
Cancers, Vol. 11, Pages 1906: MicroRNAs in Animal Models of HCC Cancers doi: 10.3390/cancers11121906 Authors: Fornari Gramantieri Callegari Shankaraiah Piscaglia Negrini Giovannini Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality. Molecular heterogeneity and absence of biomarkers for patient allocation to the best therapeutic option contribute to poor prognosis of advanced stages. Aberrant microRNA (miRNA) expression is associated...
Cancers, Vol. 11, Pages 1914: The Role of the Lymph Node Ratio in Advanced Gastric Cancer After Neoadjuvant Chemotherapy Cancers doi: 10.3390/cancers11121914 Authors: Rawicz-Pruszyński Ciseł Mlak Mielko Skórzewska Kwietniewska Pikuła Gęca Sędłak Kurylcio Polkowski The ratio of positive lymph nodes (LNs) to the total LN harvest is called the LN ratio (LNR). It is an independent prognostic factor in gastric cancer (GC). The aim of the current study...
Cancers, Vol. 11, Pages 1912: A 4-Year Retrospective Analysis of Salivary Gland Cytopathology Using the Milan System for Reporting Salivary Gland Cytology and Ancillary Studies Cancers doi: 10.3390/cancers11121912 Authors: Dubucs Basset D'Aure Courtade-Saïdi Evrard The cytopathology of salivary glands presents major challenges due to the heterogeneity of benign and malignant neoplasms, which is reflected in the large range of WHO 2017 Classifications. Fine needle aspiration...
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