Microorganisms, Vol. 7, Pages 636: Oral Microbiota Composition and Antimicrobial Antibody Response in Patients with Recurrent Aphthous StomatitisMicroorganisms doi: 10.3390/microorganisms7120636Authors: Stehlikova Tlaskal Galanova Roubalova Kreisinger Dvorak Prochazkova Kostovcikova Bartova Libanska Cermakova Schierova Fassmann Borilova Linhartova Coufal Kverka Izakovicova-Holla Petanova Tlaskalova-Hogenova Jiraskova Zakostelska Recurrent aphthous stomatitis (RAS) is the most common disease of the...
Sun Dec 01, 2019 02:00
Microorganisms, Vol. 7, Pages 634: Transcriptomic Analysis of Viable but Non-Culturable Escherichia coli O157:H7 Formation Induced by Low TemperatureMicroorganisms doi: 10.3390/microorganisms7120634Authors:Junliang ZhongXihong ZhaoEscherichia coli O157:H7 is one of the most common pathogenic bacteria that pose a threat to food safety. The aim of this study was to investigate the mechanisms of the formation of viable but non-culturable (VBNC) E. coli O157:H7 induced by low temperature (−20...
Sat Nov 30, 2019 02:00
Microorganisms, Vol. 7, Pages 635: Comparative Genomics Reveals Metabolic Specificity of Endozoicomonas Isolated from a Marine Sponge and the Genomic Repertoire for Host-Bacteria SymbiosesMicroorganisms doi: 10.3390/microorganisms7120635Authors:Anoop AlexAgostino AntunesThe most recently described bacterial members of the genus Endozoicomonas have been found in association with a wide variety of marine invertebrates. Despite their ubiquity in the host holobiont, limited information is available on...
Sat Nov 30, 2019 02:00
Microorganisms, Vol. 7, Pages 632: Effects of a Simulated Acute Oil Spillage on Bacterial Communities from Arctic and Antarctic Marine SedimentsMicroorganisms doi: 10.3390/microorganisms7120632Authors:Carmen RizzoRoberta MalavendaBerna GerçeMaria PapaleChristoph SyldatkRudolf HausmannVivia BruniLuigi MichaudAngelina Lo GiudiceStefano AmalfitanoBackground: The bacterial community responses to oil spill events are key elements to predict the fate of hydrocarbon pollution in receiving aquatic environments....
Sat Nov 30, 2019 02:00
Microorganisms, Vol. 7, Pages 633: Occurrence and Molecular Identification of Wild Yeasts from Jimma Zone, South West EthiopiaMicroorganisms doi: 10.3390/microorganisms7120633Authors:Anbessa Dabassa KorichaDa-Yong HanKetema BachaFeng-Yan BaiYeasts are common inhabitants of most fruit trees’ rhizospheres and phyllospheres. Wild yeasts are the major driving force behind several modern industrial biotechnologies. This study focused on determining the occurrence and frequency of wild yeasts...
Sat Nov 30, 2019 02:00
Microorganisms, Vol. 7, Pages 628: Establishment of a Screening Method for Epstein-Barr Virus-Associated Gastric Carcinoma by Droplet Digital PCRMicroorganisms doi: 10.3390/microorganisms7120628Authors: Shuto Nishikawa Shimokuri Yanagi Takagi Takagi Miura Iida Nagano Takemoto Harada Suehiro Yamasaki Okamoto SakaidaBackground: Epstein-Barr virus-associated gastric carcinoma (EBVaGC) is classified as one of the molecular subtypes of gastric cancer. We used droplet digital polymerase chain reaction...
Fri Nov 29, 2019 02:00
Microorganisms, Vol. 7, Pages 630: A Storable Mediatorless Electrochemical Biosensor for Herbicide DetectionMicroorganisms doi: 10.3390/microorganisms7120630Authors: Tucci Bombelli Howe Vignolini Bocchi SchievanoA novel mediatorless photo-bioelectrochemical sensor operated with a biofilm of the cyanobacterium Synechocystis PCC6803 wt. for herbicide detection with long term stability (>20 days) was successfully developed and tested. Photoanodic current generation was obtained in the absence...
Fri Nov 29, 2019 02:00
Microorganisms, Vol. 7, Pages 629: Coxiella burnetii Antibody Prevalence and Risk Factors of Infection in the Human Population of EstoniaMicroorganisms doi: 10.3390/microorganisms7120629Authors: Neare Janson Hütt Lassen ViltropQ fever is an emerging health problem in both humans and animals. To estimate the prevalence of Coxiella burnetii (C. burnetii) antibodies in the Estonian population, we analyzed plasma samples from 1000 individuals representing the general population and 556 individual serum...
Fri Nov 29, 2019 02:00
Microorganisms, Vol. 7, Pages 627: Review on Immersion Vaccines for Fish: An Update 2019Microorganisms doi: 10.3390/microorganisms7120627Authors: Bøgwald DalmoImmersion vaccines are used for a variety of aquacultured fish to protect against infectious diseases caused by bacteria and viruses. During immersion vaccination the antigens are taken up by the skin, gills or gut and processed by the immune system, where the resulting response may lead to protection. The lack of classical secondary responses...
Fri Nov 29, 2019 02:00
Microorganisms, Vol. 7, Pages 631: What Happens in the Staphylococcal Nucleoid under Oxidative Stress?Microorganisms doi: 10.3390/microorganisms7120631Authors: Morikawa Ushijima Ohniwa Miyakoshi TakeyasuThe evolutionary success of Staphylococcus aureus as an opportunistic human pathogen is largely attributed to its prominent abilities to cope with a variety of stresses and host bactericidal factors. Reactive oxygen species are important weapons in the host arsenal that inactivate phagocytosed pathogens,...
Fri Nov 29, 2019 02:00
Microorganisms, Vol. 7, Pages 626: Quantification and Multidrug Resistance Profiles of Vancomycin-Resistant Enterococci Isolated from Two Wastewater Treatment Plants in the Same MunicipalityMicroorganisms doi: 10.3390/microorganisms7120626Authors:Haley SandersonRodrigo Ortega-PoloKevin McDermottGeoffrey HallRahat ZaheerR. Stephen BrownAnna MajuryTim A. McAllisterSteven N. LissWastewater treatment plants (WWTPs) are points of control for the environmental dissemination of antimicrobial resistant bacteria....
Fri Nov 29, 2019 02:00
Microorganisms, Vol. 7, Pages 625: Bacteriophage and the Innate Immune System: Access and SignalingMicroorganisms doi: 10.3390/microorganisms7120625Authors: Carroll-Portillo LinBacteriophage and the bacteria they infect are the dominant members of the gastrointestinal microbiome. While bacteria are known to be central to maintenance of the structure, function, and health of the microbiome, it has only recently been recognized that phage too might serve a critical function. Along these lines, bacteria...
Thu Nov 28, 2019 02:00
Microorganisms, Vol. 7, Pages 624: Environmental DNA Sequencing Reveals a Highly Complex Eukaryote Community in Sansha Yongle Blue Hole, Xisha, South China SeaMicroorganisms doi: 10.3390/microorganisms7120624Authors:Yueteng LiuHui HeLiang FuQian LiuZuosheng YangYu ZhenWe report an Illumina high-throughput sequencing protocol of eukaryotic microbes in the world’s deepest marine blue hole, Sansha Yongle Blue Hole, Xisha, South China Sea. The variable V9 region of small subunit (SSU) rDNA,...
Thu Nov 28, 2019 02:00
Microorganisms, Vol. 7, Pages 623: PgRsp Is a Novel Redox-Sensing Transcription Regulator Essential for Porphyromonas gingivalis VirulenceMicroorganisms doi: 10.3390/microorganisms7120623Authors:Michał ŚmigaTeresa OlczakPorphyromonas gingivalis is one of the etiological agents of chronic periodontitis. Both heme and oxidative stress impact expression of genes responsible for its survival and virulence. Previously we showed that P. gingivalis ferric uptake regulator homolog affects expression of a...
Thu Nov 28, 2019 02:00
Microorganisms, Vol. 7, Pages 622: Longitudinal Analysis of the Microbiota Composition and Enterotypes of Pigs from Post-Weaning to FinishingMicroorganisms doi: 10.3390/microorganisms7120622Authors:Mathilde Le SciellourDavid RenaudeauOlivier ZembThe present study aimed at investigating the evolution of pigs’ fecal microbiota composition from post-weaning to finishing in a longitudinal analysis. The experiment was conducted on 160 Pietrain × (Large White × Landrace) castrated...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4397: Poly(Dopamine) Coating on 3D-Printed Poly-Lactic-Co-Glycolic Acid/β-Tricalcium Phosphate Scaffolds for Bone Tissue Engineering Molecules doi: 10.3390/molecules24234397 Authors: Zhimin Xu Ningning Wang Peng Liu Yidan Sun Yumeng Wang Fan Fei Shichen Zhang Jianying Zheng Bing Han Bone defects caused by osteoporosis, bone malignant tumors, and trauma are very common, but there are many limiting factors in the clinical treatment of them....
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Molecules, Vol. 24, Pages 4396: Influence of Storage Time and Temperature on the Toxicity, Endocrine Potential, and Migration of Epoxy Resin Precursors in Extracts of Food Packaging Materials Molecules doi: 10.3390/molecules24234396 Authors: Błażej Kudłak Natalia Jatkowska Paweł Kubica Galina Yotova Stefan Tsakovski The aim of the present study was to establish a standard methodology for the extraction of epoxy resin precursors from several types of food packages (cans, multi-layered...
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Molecules, Vol. 24, Pages 4394: Effects of Propolis Extract and Propolis-Derived Compounds on Obesity and Diabetes: Knowledge from Cellular and Animal Models Molecules doi: 10.3390/molecules24234394 Authors: Kitamura Propolis is a natural product resulting from the mixing of bee secretions with botanical exudates. Since propolis is rich in flavonoids and cinnamic acid derivatives, the application of propolis extracts has been tried in therapies against cancer, inflammation, and metabolic...
Sun Dec 01, 2019 02:00
Molecules, Vol. 24, Pages 4393: Construction of Quantitative Structure Activity Relationship (QSAR) Models to Predict Potency of Structurally Diversed Janus Kinase 2 Inhibitors Molecules doi: 10.3390/molecules24234393 Authors: Saw Simeon Nathjanan Jongkon Janus kinase 2 (JAK2) inhibitors represent a promising therapeutic class of anticancer agents against many myeloproliferative disorders. Bioactivity data on pIC 50 of 2229 JAK2 inhibitors were employed in the construction...
Sun Dec 01, 2019 02:00
Molecules, Vol. 24, Pages 4392: Improving the Yields and Reaction Rate in the Ethanolysis of Soybean Oil by Using Mixtures of Lipase CLEAs Molecules doi: 10.3390/molecules24234392 Authors: Margarita Díaz Ramos Letícia Passos Miranda Roberto Fernandez-Lafuente William Kopp Paulo Waldir Tardioli Due to the heterogeneity of oils, the use of mixtures of lipases with different activity for a large number of glycerol-linked carboxylic acids that compose the substrate has been proposed...
Sun Dec 01, 2019 02:00
Molecules, Vol. 24, Pages 4391: The Hydrophobicity of Lignocellulosic Fiber Network Can Be Enhanced with Suberin Fatty Acids Molecules doi: 10.3390/molecules24234391 Authors: Risto I. Korpinen Petri Kilpeläinen Tytti Sarjala Maristiina Nurmi Pauliina Saloranta Thomas Holmbom Hanna Koivula Kirsi S. Mikkonen Stefan Willför Pekka T. Saranpää Suberin fatty acids were extracted from outer bark of Silver birch (Betula pendula Roth.) using an isopropanolic sodium...
Sun Dec 01, 2019 02:00
Molecules, Vol. 24, Pages 4390: Expanding the Toolbox for Label-Free Enzyme Assays: A Dinuclear Platinum(II) Complex/DNA Ensemble with Switchable Near-IR Emission Molecules doi: 10.3390/molecules24234390 Authors: Moustafa T. Gabr F. Christopher Pigge Switchable luminescent bioprobes whose emission can be turned on as a function of specific enzymatic activity are emerging as important tools in chemical biology. We report a promising platform for the development of label-free and continuous...
Sun Dec 01, 2019 02:00
Molecules, Vol. 24, Pages 4389: Design, Synthesis, and In Vitro Activity of Pyrazine Compounds Molecules doi: 10.3390/molecules24234389 Authors: Panagiotis Parsonidis Mahammad Shaik Athanasia Panagiota Serafeim Ioanna Vlachou Vasiliki Daikopoulou Ioannis Papasotiriou Despite the fact that there are several anticancer drugs available, cancer has evolved using different pathways inside the cell. The protein tyrosine phosphatases pathway is responsible for monitoring cell...
Sun Dec 01, 2019 02:00
Molecules, Vol. 24, Pages 4387: Stacks of Azobenzene Stars: Self-Assembly Scenario and Stabilising Forces Quantified in Computer Modelling Molecules doi: 10.3390/molecules24234387 Authors: Vladyslav Savchenko Markus Koch Aleksander S. Pavlov Marina Saphiannikova Olga Guskova In this paper, the columnar supramolecular aggregates of photosensitive star-shaped azobenzenes with benzene-1,3,5-tricarboxamide core and azobenzene arms are analyzed theoretically by applying a combination...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4388: Design, Synthesis, and Structural Characterization of Novel Diazaphenothiazines with 1,2,3-Triazole Substituents as Promising Antiproliferative Agents Molecules doi: 10.3390/molecules24234388 Authors: Morak-Młodawska Pluta Latocha Jeleń Kuśmierz A series of novel 1,2,3-triazole-diazphenothiazine hybrids was designed, synthesized, and evaluated for anticancer activity against four selected human tumor cell lines (SNB-19, Caco-2, A549, and...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4386: Curcumin and Its Derivatives as Potential Therapeutic Agents in Prostate, Colon and Breast Cancers Molecules doi: 10.3390/molecules24234386 Authors: Zintle Mbese Vuyolwethu Khwaza Blessing Atim Aderibigbe Cancer is a life-threatening disease and is the second leading cause of death around the world. The increasing threats of drug-resistant cancers indicate that there is an urgent need for the improvement or development of more effective anticancer...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4385: Development of a Microfluidic Array to Study Drug Response in Breast Cancer Molecules doi: 10.3390/molecules24234385 Authors: Virumbrales-Muñoz Livingston Farooqui Skala Beebe Ayuso Luminal geometries are common structures in biology, which are challenging to mimic using conventional in vitro techniques based on the use of Petri dishes. In this context, microfluidic systems can mimic the lumen geometry, enabling a large variety of...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4383: Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression Molecules doi: 10.3390/molecules24234383 Authors: Dan Liao Wei Zhang Pranav Gupta Zi-Ning Lei Jing-Quan Wang Chao-Yun Cai Albert A. De Vera Lei Zhang Zhe-Sheng Chen Dong-Hua Yang The overexpression of ABC transporters induced by anticancer drugs has been found...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4381: Fiber-Array-Based Raman Hyperspectral Imaging for Simultaneous, Chemically-Selective Monitoring of Particle Size and Shape of Active Ingredients in Analgesic Tablets Molecules doi: 10.3390/molecules24234381 Authors: Timea Frosch Elisabeth Wyrwich Di Yan Juergen Popp Torsten Frosch The particle shape, size and distribution of active pharmaceutical ingredients (API) are relevant quality indicators of pharmaceutical tablets due to their high impact...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4382: Phytofabrication of Silver/Silver Chloride Nanoparticles Using Aqueous Leaf Extract of Oedera genistifolia: Characterization and Antibacterial Potential Molecules doi: 10.3390/molecules24234382 Authors: Kunle Okaiyeto Mike O. Ojemaye Heinrich Hoppe Leonard V. Mabinya Anthony I. Okoh In this present study, silver nanoparticles (Ag/AgCl NPs) were synthesized using an aqueous leaf extract of Oedera genistifolia as a reducing agent. The biosynthesized...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4384: Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer Molecules doi: 10.3390/molecules24234384 Authors: Nannan Li Wenxiao Men Yibo Zheng Hechen Wang Xiansheng Meng This study aims to investigate the anticancer effect of Oroxin B (OB) both in vitro and in vivo, and the molecular mechanism involved in microRNA-221 and the PI3K/Akt/PTEN pathway through modulation of...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4380: The Synthesis, Self-Assembled Structures, and Microbicidal Activity of Cationic Gemini Surfactants with Branched Tridecyl Chains Molecules doi: 10.3390/molecules24234380 Authors: Martin Pisárčik Matúš Pupák Miloš Lukáč Ferdinand Devínsky Lukáš Hubčík Marián Bukovský Branislav Horváth Cationic gemini surfactants with polymethylene spacer and linear alkyl chains containing an even number of carbon atoms have been extensively studied in...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4378: Green Synthesis and Electrochemical Properties of Mono- and Dimers Derived from Phenylaminoisoquinolinequinones Molecules doi: 10.3390/molecules24234378 Authors: Juana Andrea Ibacache Jaime A. Valderrama Judith Faúndes Alex Danimann Francisco J. Recio César A. Zúñiga In the search for new quinoid compounds endowed with potential anticancer activity, the synthesis of novel heterodimers containing the cytotoxic 7-phenylaminoisoquinolinequinone...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4379: Neuroprotective Norsesquiterpenoids and Triterpenoids from Populus euphratica Resins Molecules doi: 10.3390/molecules24234379 Authors: Yun-Yun Liu Dan-Ling Huang Yun Dong Da-Peng Qin Yong-Ming Yan Yong-Xian Cheng Two new octanorlanostane-type triterpenes, euphraticanoids A and B (1 and 2), two new trinorsesquiterpenoids, euphraticanoids C and D (3 and 4), and eight known triterpenoids (5, 6, 8–13) along with one steroid (7) were...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4377: Anything You Can Do, I Can Do Better: Can Aptamers Replace Antibodies in Clinical Diagnostic Applications? Molecules doi: 10.3390/molecules24234377 Authors: Michelle Bauer Mia Strom David S Hammond Sarah Shigdar The mainstay of clinical diagnostics is the use of specialised ligands that can recognise specific biomarkers relating to pathological changes. While protein antibodies have been utilised in these assays for the last 40 years, they have...
Sat Nov 30, 2019 02:00
Molecules, Vol. 24, Pages 4376: Organic Acids and Polyphenols Determination in Polish Wines by Ultrasound-Assisted Solvent Extraction of Porous Membrane-Packed Liquid Samples Molecules doi: 10.3390/molecules24234376 Authors: Robles Fabjanowicz Płotka-Wasylka Konieczka In the near future, Poland is going to have more and more favorable conditions for viticulture. Organic acids and polyphenols are among the most commonly analyzed compounds due to their beneficial properties...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4375: Anti-Inflammatory Derivatives with Dual Mechanism of Action from the Metabolomic Screening of Poincianella pluviosa Molecules doi: 10.3390/molecules24234375 Authors: Olívia da S. Domingos Bianca G. V. Alcântara Mário F. C. Santos Tatiane C. S. Maiolini Danielle F. Dias João L. Baldim João Henrique G. Lago Marisi G. Soares Daniela A. Chagas-Paula Metabolomics approaches have become fundamental strategies for the analysis of complex...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4374: Effects of Molecular Weight and Guluronic Acid/Mannuronic Acid Ratio on the Rheological Behavior and Stabilizing Property of Sodium Alginate Molecules doi: 10.3390/molecules24234374 Authors: Wenxiao Jiao Wenxue Chen Yuqi Mei Yonghuan Yun Boqiang Wang Qiuping Zhong Haiming Chen Weijun Chen The aim of this study was to prepare sodium alginates (SAs) with different molecular weight and G/M ratio, and characterize their rheological behaviors...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4372: Inhibitors of Brassinosteroid Biosynthesis and Signal Transduction Molecules doi: 10.3390/molecules24234372 Authors: Wilfried Rozhon Sonia Akter Atiara Fernandez Brigitte Poppenberger Chemical inhibitors are invaluable tools for investigating protein function in reverse genetic approaches. Their application bears many advantages over mutant generation and characterization. Inhibitors can overcome functional redundancy, their application is not...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4371: Glycol Chitosan: A Water-Soluble Polymer for Cell Imaging and Drug Delivery Molecules doi: 10.3390/molecules24234371 Authors: Fengming Lin Hao-Ran Jia Fu-Gen Wu Glycol chitosan (GC), a water-soluble chitosan derivative with hydrophilic ethylene glycol branches, has both hydrophobic segments for the encapsulation of various drugs and reactive functional groups for facile chemical modifications. Over the past two decades, a variety of molecules have...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4369: Inhibition of Porcine Aminopeptidase M (pAMP) by the Pentapeptide Microginins Molecules doi: 10.3390/molecules24234369 Authors: Glaucio Monteiro Ferreira Thales Kronenberger Éryka Costa de Almeida Joseane Sampaio Clélia Ferreira Terra Ernani Pinto Gustavo Henrique Goulart Trossini Aminopeptidase M (AMP) inhibition is of interest for several diseases, such as highly vascularized cancer types. AMP can be inhibited by linear pentapeptides...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4370: Advances in Near-Infrared Spectroscopy and Related Computational Methods Molecules doi: 10.3390/molecules24234370 Authors: Krzysztof B. Beć Christian W. Huck Over the last few decades, near-infrared (NIR) spectroscopy has distinguished itself as one of the most rapidly advancing spectroscopic techniques [...]
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4373: A Repurposing Approach for Uncovering the Anti-Tubercular Activity of FDA-Approved Drugs with Potential Multi-Targeting Profiles Molecules doi: 10.3390/molecules24234373 Authors: Basem Battah Giulia Chemi Stefania Butini Giuseppe Campiani Simone Brogi Giovanni Delogu Sandra Gemma Tuberculosis (TB) is one of the top 10 causes of death worldwide. This scenario is further complicated by the insurgence of multidrug-resistant (MDR) and extensively...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4367: Preparation of Polyethylene Glycol-Ginsenoside Rh1 and Rh2 Conjugates and Their Efficacy against Lung Cancer and Inflammation Molecules doi: 10.3390/molecules24234367 Authors: Ramya Mathiyalagan Chao Wang Yeon Ju Kim Verónica Castro-Aceituno Sungeun Ahn Sathiyamoorthy Subramaniyam Shakina Yesmin Simu Zuly Elizabeth Jiménez-Pérez Deok Chun Yang Seok-Kyu Jung Low solubility and tumor-targeted delivery of ginsenosides to avoid off-target...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4365: Catalytic Ozonation of Organics in Reverse Osmosis Concentrate with Catalysts Based on Activated Carbon Molecules doi: 10.3390/molecules24234365 Authors: Xieyang Xu Zhilin Xia Laisheng Li Qi Huang Can He Jianbing Wang Acid-washed activated carbon (AC-A), nitric acid modified activated carbon (AC-NO2), aminated activated carbon (AC-NH2) and cerium-loaded activated carbon (Ce/AC) were prepared and characterized by BET procedure, Boehm titration...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4368: Scented Tartary Buckwheat Tea: Aroma Components and Antioxidant Activity Molecules doi: 10.3390/molecules24234368 Authors: Qinglian Xu Li Wang Wenxiu Li Yage Xing Ping Zhang Qin Wang He Li Hong Liu Hua Yang Xiaocui Liu Yuan Ma In this study, the aroma compounds of Huantai tartary buckwheat tea (TBH), three laboratory-produced scented tartary buckwheat teas, as well as the antioxidant activity of tea infusion was investigated....
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4364: Highly Sensitive Detection of PCV2 Based on Tyramide Signals and GNPL Amplification Molecules doi: 10.3390/molecules24234364 Authors: Shouping Zhang Bin Hu Xiaojing Xia Yanzhao Xu Bolin Hang Jinqing Jiang Jianhe Hu The frequent emergence of secondary infection and immunosuppression after porcine circovirus type 2 (PCV2) infection highlights the need to develop sensitive detection methods. A dual-signal amplification enzyme-linked immunosorbent...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4366: Mercapto-Functionalized Porous Organosilica Monoliths Loaded with Gold Nanoparticles for Catalytic Application Molecules doi: 10.3390/molecules24234366 Authors: Hongwei Li Junhui Pan Chengtao Gao Mengyu Ma Liangyu Lu Yuzhu Xiong Fuping Dong Porous organosilica monoliths have attracted much attention from both the academic and industrial fields due to their porous structure; excellent mechanical property and easily functionalized surface....
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4363: Design and Synthesis of N-phenyl Phthalimides as Potent Protoporphyrinogen Oxidase Inhibitors Molecules doi: 10.3390/molecules24234363 Authors: Wei Gao Xiaotian Li Da Ren Susu Sun Jingqian Huo Yanen Wang Lai Chen Jinlin Zhang Protoporphyrinogen oxidase (PPO) has been identified as one of the most promising targets for herbicide discovery. A series of novel phthalimide derivatives were designed by molecular docking studies targeting...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4362: Antioxidant, Antimutagenic and Cytoprotective Properties of Hydrosos Pistachio Nuts Molecules doi: 10.3390/molecules24234362 Authors: Luis Noguera-Artiaga Joel Said García-Romo Ema C. Rosas-Burgos Francisco Javier Cinco-Moroyoqui Reyna Luz Vidal-Quintanar Ángel Antonio Carbonell-Barrachina Armando Burgos-Hernández Pistachio nuts are included among the foods with the highest antioxidant capacity. Stressed cultivating conditions, such as...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4360: Tetramethoxystilbene-Loaded Liposomes Restore Reactive-Oxygen-Species-Mediated Attenuation of Dilator Responses in Rat Aortic Vessels Ex vivo Molecules doi: 10.3390/molecules24234360 Authors: Azziza Zaabalawi Cai Astley Lewis Renshall Frances Beards Adam P. Lightfoot Hans Degens Debra Whitehead Yvonne Alexander Lynda K Harris May Azzawi The methylated analogue of the polyphenol resveratrol (RV), 2,3′,4,5′-tetramethoxystilbene...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4361: Halogen-Bond Assisted Photoinduced Electron Transfer Molecules doi: 10.3390/molecules24234361 Authors: Bogdan Dereka Ina Fureraj Arnulf Rosspeintner Eric Vauthey The formation of a halogen-bond (XB) complex in the excited state was recently reported with a quadrupolar acceptor–donor–acceptor dye in two iodine-based liquids (J. Phys. Chem. Lett. 2017, 8, 3927–3932). The ultrafast decay of this excited complex to the...
Fri Nov 29, 2019 02:00
Molecules, Vol. 24, Pages 4358: A Comprehensive QSAR Study on Antileishmanial and Antitrypanosomal Cinnamate Ester Analogues Molecules doi: 10.3390/molecules24234358 Authors: Freddy A. Bernal Thomas J. Schmidt Parasitic infections like leishmaniasis and trypanosomiasis remain as a worldwide concern to public health. Improvement of the currently available drug discovery pipelines for those diseases is therefore mandatory. We have recently reported on the antileishmanial and antitrypanosomal...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4357: Thiyl Radical Reactions in the Chemical Degradation of Pharmaceutical Proteins Molecules doi: 10.3390/molecules24234357 Authors: Schöneich Free radical pathways play a major role in the degradation of protein pharmaceuticals. Inspired by biochemical reactions carried out by thiyl radicals in various enzymatic processes, this review focuses on the role of thiyl radicals in pharmaceutical protein degradation through hydrogen atom transfer, electron transfer,...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4355: Matrix Metalloproteinase Triple-Helical Peptide Inhibitors: Potential Cross-Reactivity with Caspase-11 Molecules doi: 10.3390/molecules24234355 Authors: Anna M. Knapinska Melissa Hart Gary Drotleff Gregg B. Fields Triple-helical peptide inhibitors (THPIs) of matrix metalloproteinases (MMPs) have recently been demonstrated to be effective in a variety of animal models of disease, coincidental with knockout studies. However, passenger mutations...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4356: Insights into Mechanisms of Electrochemical Drug Degradation in Their Mixtures in the Split-Flow Reactor Molecules doi: 10.3390/molecules24234356 Authors: Pieczyńska Ochoa-Chavez Wilczewska Bielicka-Giełdoń Siedlecka The recirculating split-flow batch reactor with a cell divided into anolyte and catholyte compartments for oxidation mixture of cytostatic drugs (CD) was tested. In this study, kinetics and mechanisms of electrochemical oxidization...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4359: Path Integral Calculation of the Hydrogen/Deuterium Kinetic Isotope Effect in Monoamine Oxidase A-Catalyzed Decomposition of Benzylamine Molecules doi: 10.3390/molecules24234359 Authors: Mateusz Z. Brela Alja Prah Marek Boczar Jernej Stare Janez Mavri Monoamine oxidase A (MAO A) is a well-known enzyme responsible for the oxidative deamination of several important monoaminergic neurotransmitters. The rate-limiting step of amine decomposition...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4353: Triterpenes and Aromatic Meroterpenoids with Antioxidant Activity and Neuroprotective Effects from Ganoderma lucidum Molecules doi: 10.3390/molecules24234353 Authors: Cuifang Wang Xuemin Liu Chenlei Lian Jiaying Ke Jieqing Liu Reactive oxygen/nitrogen species generated in the human body can cause oxidative damage associated with many degenerative diseases such as atherosclerosis, dementia, coronary heart diseases, aging, and cancer. There is...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4354: A Review of Bark-Extract-Mediated Green Synthesis of Metallic Nanoparticles and Their Applications Molecules doi: 10.3390/molecules24234354 Authors: Ema Burlacu Corneliu Tanase Năstaca-Alina Coman Lavinia Berta Nanoparticles are intensely studied because of their importance in diverse fields of biotechnology, especially in medicine. This paper highlights that waste bark can be a cheap source of biocompounds, with high recovery and functionalization...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4351: Discovery of a Potent PLK1-PBD Small-Molecule Inhibitor as an Anticancer Drug Candidate through Structure-Based Design Molecules doi: 10.3390/molecules24234351 Authors: Yunjiang Zhou Fang Yan Xiangyun Huo Miao-Miao Niu Polo-box domain of polo-like kinase 1 (PLK1-PBD) has a pivotal role in cell proliferation and could be implicated as a potential anticancer target. Although some small-molecule inhibitors have been developed, their clinical application...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4350: Study on the Separation of H2 from CO2 Using a ZIF-8 Membrane by Molecular Simulation and Maxwell-Stefan Model Molecules doi: 10.3390/molecules24234350 Authors: Behrouz Bayati Asma Ghorbani Kamran Ghasemzadeh Adolfo Iulianelli Angelo Basile The purification of H2-rich streams using membranes represents an important separation process, particularly important in the viewpoint of pre-combustion CO2 capture. In this study, the separation of H2...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4352: Comparison and Identification of the Aroma-Active Compounds in the Root of Angelica dahurica Molecules doi: 10.3390/molecules24234352 Authors: Die Hu Junrui Guo Ting Li Mu Zhao Tingting Zou Huanlu Song Aygul Alim Solid-phase microextraction (SPME), purge and trap (P&T), stir bar sportive extraction (SBSE), and dynamic headspace sampling (DHS) were applied to extract, separate and analyze the volatile compounds in the roots of...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4349: Combination of Lactobacillus plantarum and Saccharomyces cerevisiae DV10 as Starter Culture to Produce Mango Slurry: Microbiological, Chemical Parameters and Antioxidant Activity Molecules doi: 10.3390/molecules24234349 Authors: Xiaofan Jin Wenxue Chen Haiming Chen Weijun Chen Qiuping Zhong The aim of this study was to develop a nondairy fermented product based on mango slurry. Lactobacillus plantarum and Saccharomyces cerevisiae DV10 were...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4347: Sustainable and Selective Extraction of Lipids and Bioactive Compounds from Microalgae Molecules doi: 10.3390/molecules24234347 Authors: Ilaria Santoro Monica Nardi Cinzia Benincasa Paola Costanzo Girolamo Giordano Antonio Procopio Giovanni Sindona The procedures for the extraction and separation of lipids and nutraceutics from microalgae using classic solvents have been frequently used over the years. However, these production methods...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4348: Current Advances in the Synthesis of Valuable Dipyrromethane Scaffolds: Classic and New Methods Molecules doi: 10.3390/molecules24234348 Authors: Bruno F. O. Nascimento Susana M. M. Lopes Marta Pineiro Teresa M. V. D. Pinho e Melo This review presents the most recent developments on the synthesis of dipyrromethanes, covering classical synthetic strategies, using acid catalyzed condensation of pyrroles and aldehydes or ketones, and recent breakthroughs...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4346: Discovery and Characterisation of Dual Inhibitors of Tryptophan 2,3-Dioxygenase (TDO2) and Indoleamine 2,3-Dioxygenase 1 (IDO1) Using Virtual Screening Molecules doi: 10.3390/molecules24234346 Authors: Suat Sari Petr Tomek Euphemia Leung Jóhannes Reynisson Cancers express tryptophan catabolising enzymes indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO2) to produce immunosuppressive tryptophan metabolites that undermine...
Thu Nov 28, 2019 02:00
Molecules, Vol. 24, Pages 4345: Tuning Mechanical Properties of Pseudopeptide Supramolecular Hydrogels by Graphene Doping Molecules doi: 10.3390/molecules24234345 Authors: Demetra Giuri Marianna Barbalinardo Nicola Zanna Paolo Paci Marco Montalti Massimiliano Cavallini Francesco Valle Matteo Calvaresi Claudia Tomasini Supramolecular hydrogels, obtained from small organic molecules, may be advantageous over polymeric ones for several applications, because these...
Thu Nov 28, 2019 02:00
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