JCM, Vol. 8, Pages 2098: Clinical Validation of Innovative Optical-Sensor-Based, Low-Cost, Rapid Diagnostic Test to Reduce Antimicrobial Resistance Journal of Clinical Medicine doi: 10.3390/jcm8122098 Authors: Kapur Gehani Kammili Bhardwaj Nag Devara Sharad The antibiotic susceptibility test determines the most effective antibiotic treatment for bacterial infection. Antimicrobial stewardship is advocated for the rational use of antibiotics to preserve their efficacy...
JCM, Vol. 8, Pages 2097: Exercise Training as a Treatment for Cardiometabolic Risk in Sedentary Adults: Are Physical Activity Guidelines the Best Way to Improve Cardiometabolic Health? The FIT-AGEING Randomized Controlled Trial Journal of Clinical Medicine doi: 10.3390/jcm8122097 Authors: Amaro-Gahete De-la-O Jurado-Fasoli Martinez-Tellez Ruiz Castillo This 12-week randomized controlled trial investigates the effects of different training modalities on cardiometabolic...
JCM, Vol. 8, Pages 2099: Anxiety and Depression in Patients with Obstructive Sleep Apnoea before and after Continuous Positive Airway Pressure: The ADIPOSA Study Journal of Clinical Medicine doi: 10.3390/jcm8122099 Authors: Carneiro-Barrera Amaro-Gahete Sáez-Roca Martín-Carrasco Ruiz Buela-Casal The prevalence and treatment response of depression and anxiety symptoms in obstructive sleep apnoea (OSA), although widely addressed in research and clinical settings, still...
JCM, Vol. 8, Pages 2095: Encouraging Split Liver Transplantation for Two Adult Recipients to Mitigate the High Incidence of Wait-list Mortality in The Setting of Extreme Shortage of Deceased Donors Journal of Clinical Medicine doi: 10.3390/jcm8122095 Authors: Chan Wang Wu Cheng Lee Wu Chou Lee Background: Organ demand for liver transplantation (LT) is constantly increasing. Split liver transplantation (SPLT) is an ideal option for increasing the number of...
JCM, Vol. 8, Pages 2094: Surgery of True Recurring Median Carpal Tunnel Syndrome with Synovial Flap by Wulle Plus Integument Enlargement Leads to a High Patient’s Satisfaction and Improved Functionality Journal of Clinical Medicine doi: 10.3390/jcm8122094 Authors: Payr Tiefenboeck Moser Turkof This prospective study was conducted to investigate electrophysiological qualities and patient’s satisfaction of a synovial gliding tissue flap in treating true recurring...
JCM, Vol. 8, Pages 2083: Bioengineered Skin Substitutes: the Role of Extracellular Matrix and Vascularization in the Healing of Deep Wounds Journal of Clinical Medicine doi: 10.3390/jcm8122083 Authors: Urciuolo Casale Imparato Netti The formation of severe scars still represents the result of the closure process of extended and deep skin wounds. To address this issue, different bioengineered skin substitutes have been developed but a general consensus regarding their effectiveness...
JCM, Vol. 8, Pages 2096: Architecture of the Triceps Surae Muscles Complex in Patients with Spastic Hemiplegia: Implication for the Limited Utility of the Silfverskiöld Test Journal of Clinical Medicine doi: 10.3390/jcm8122096 Authors: Park Joo Park Rhee Shin Abdel-Baki Kim The Silfverskiöld test has long been used as an important tool for determining the affected muscles of the triceps surae in patients with equinus deformity. However, the test may...
JCM, Vol. 8, Pages 2091: Periprosthetic Osteolysis: Mechanisms, Prevention and Treatment Journal of Clinical Medicine doi: 10.3390/jcm8122091 Authors: Goodman Gallo Clinical studies, as well as in vitro and in vivo experiments have demonstrated that byproducts from joint replacements induce an inflammatory reaction that can result in periprosthetic osteolysis (PPOL) and aseptic loosening (AL). Particle-stimulated macrophages and other cells release cytokines, chemokines, and other...
JCM, Vol. 8, Pages 2088: The Reeler Mouse: A Translational Model of Human Neurological Conditions, or Simply a Good Tool for Better Understanding Neurodevelopment? Journal of Clinical Medicine doi: 10.3390/jcm8122088 Authors: Lossi Castagna Granato Merighi The first description of the Reeler mutation in mouse dates to more than fifty years ago, and later, its causative gene (reln) was discovered in mouse, and its human orthologue (RELN) was demonstrated to be causative of...
JCM, Vol. 8, Pages 2089: Enhancement of Antiviral CD8+ T-Cell Responses and Complete Remission of Metastatic Melanoma in an HIV-1-Infected Subject Treated with Pembrolizumab Journal of Clinical Medicine doi: 10.3390/jcm8122089 Authors: Oscar Blanch-Lombarte Cristina Gálvez Boris Revollo Esther Jiménez-Moyano Josep M. Llibre José Luís Manzano Aram Boada Judith Dalmau Daniel E. Speiser Bonaventura Clotet Julia G. Prado Javier Martinez-Picado Background:...
JCM, Vol. 8, Pages 2087: Results from the Adverse Event Sedation Reporting Tool: A Global Anthology of 7952 Records Derived from >160,000 Procedural Sedation Encounters Journal of Clinical Medicine doi: 10.3390/jcm8122087 Authors: Keira P. Mason Mark G. Roback David Chrisp Nicole Sturzenbaum Lee Freeman David Gozal Firoz Vellani David Cavanaugh Steven M. Green Background: The incidence of sedation-related adverse events, inclusive of both adults and children,...
JCM, Vol. 8, Pages 2092: Complications after Chest Tube Removal and Reinterventions in Patients with Digital Drainage Systems Journal of Clinical Medicine doi: 10.3390/jcm8122092 Authors: Yi-Ying Lee Po-Kuei Hsu Chien-Sheng Huang Yu-Chung Wu Han-Shui Hsu Introduction: Digital thoracic drainage systems are a new technology in minimally invasive thoracic surgery. However, the criteria for chest tube removal in digital thoracic drainage systems have never been evaluated. We...
JCM, Vol. 8, Pages 2090: Metabolic Syndrome Including Glycated Hemoglobin A1c in Adults: Is It Time to Change? Journal of Clinical Medicine doi: 10.3390/jcm8122090 Authors: Iván Cavero-Redondo Vicente Martínez-Vizcaíno Celia Álvarez-Bueno Cristina Agudo-Conde Cristina Lugones-Sánchez Luis García-Ortiz (1) Background: To assess the suitability of replacing conventional markers used for insulin resistance and dysglycemia by HbA1c in both the quantitative and qualitative...
JCM, Vol. 8, Pages 2086: Preventive Effect of Cardiotrophin-1 Administration before DSS-Induced Ulcerative Colitis in Mice Journal of Clinical Medicine doi: 10.3390/jcm8122086 Authors: Ana I. Sánchez-Garrido Vanessa Prieto-Vicente Víctor Blanco-Gozalo Miguel Arévalo Yaremi Quiros Daniel López-Montañés Francisco J. López-Hernández Antonio Rodríguez-Pérez José M. López-Novoa Ulcerative colitis is a relatively frequent, chronic disease that impacts significantly...
JCM, Vol. 8, Pages 2093: Evaluation of Patellar Contact Pressure Changes after Static versus Dynamic Medial Patellofemoral Ligament Reconstructions Using a Finite Element Model Journal of Clinical Medicine doi: 10.3390/jcm8122093 Authors: Sanchis-Alfonso Ginovart Alastruey-López Montesinos-Berry Monllau Alberich-Bayarri Pérez Objectives: To evaluate the effect of various medial patellofemoral ligament (MPFL) fixation techniques on patellar pressure compared with...
JCM, Vol. 8, Pages 2084: Plasmapheresis Reduces Mycophenolic Acid Concentration: A Study of Full AUC0–12 in Kidney Transplant Recipients Journal of Clinical Medicine doi: 10.3390/jcm8122084 Authors: Sudarat Piyasiridej Natavudh Townamchai Suwasin Udomkarnjananun Somratai Vadcharavivad Krit Pongpirul Salin Wattanatorn Boonchoo Sirichindakul Yingyos Avihingsanon Kriang Tungsanga Somchai Eiam-Ong Kearkiat Praditpornsilpa Background: Mycophenolic acid (MPA),...
JCM, Vol. 8, Pages 2085: Correlation between Hepatitis B Virus Infection and Colorectal Neoplasia Journal of Clinical Medicine doi: 10.3390/jcm8122085 Authors: Yoon Suk Jung Nam Hee Kim Jung Ho Park Dong Il Park Chong Il Sohn Background: Data about the association between hepatitis virus infection and colorectal neoplasia (CRN) are extremely limited. We examined the association between hepatitis B virus (HBV) and hepatitis C virus (HCV) infection with the risk of CRN. Methods:...
JCM, Vol. 8, Pages 2082: AAV Mediated Delivery of Myxoma Virus M013 Gene Protects the Retina against Autoimmune Uveitis Journal of Clinical Medicine doi: 10.3390/jcm8122082 Authors: Ridley Young Lee Walsh Ahmed Lewin Ildefonso Uveoretinitis is an ocular autoimmune disease caused by the activation of autoreactive T- cells targeting retinal antigens. The myxoma M013 gene is known to block NF-κB (Nuclear Factor kappa-light-chain-enhancer of activated B...
JCM, Vol. 8, Pages 2080: Predicting Residual Function in Hemodialysis and Hemodiafiltration—A Population Kinetic, Decision Analytic Approach Journal of Clinical Medicine doi: 10.3390/jcm8122080 Authors: Achakzai Argyropoulos Roumelioti In this study, we introduce a novel framework for the estimation of residual renal function (RRF), based on the population compartmental kinetic behavior of beta 2 microglobulin (B2M) and its dialytic removal. Using this model, we simulated a...
JCM, Vol. 8, Pages 2081: Changes in the Clinicopathological Demographics of Vulvar Cancer in Japan: Increasing Oldest-Old, Stage Shifting, and Decreasing Cohort-Level Survival † Journal of Clinical Medicine doi: 10.3390/jcm8122081 Authors: Shin Nishio Koji Matsuo Takeo Shibata Satoshi Yamaguchi Hiroyuki Kanao Kazuhiro Takehara Nobuhiro Kado Akiko Tozawa Hideki Tokunaga Tatsuya Matsunaga Hisamori Kato Koji Horie Akira Kikuchi Takayuki Enomoto Mikio...
JCM, Vol. 8, Pages 2079: Case-matched Comparison of Cardiovascular Outcome in Loeys-Dietz Syndrome versus Marfan Syndrome Journal of Clinical Medicine doi: 10.3390/jcm8122079 Authors: Kristina Mühlstädt Julie De Backer Yskert von Kodolitsch Kerstin Kutsche Laura Muiño Mosquera Jens Brickwedel Evaldas Girdauskas Thomas S. Mir Adrian Mahlmann Nikolaos Tsilimparis Axel Staebler Lauritz Schoof Heide Seidel Jürgen Berger Alexander M. Bernhardt Stefan...
JCM, Vol. 8, Pages 2078: Optical Coherence Tomography Angiography Imaging in Inherited Retinal Diseases Journal of Clinical Medicine doi: 10.3390/jcm8122078 Authors: Ong Patel Singh Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the retina and the choroid. It is a powerful research tool to study the pathobiology of retinal diseases, including inherited retinal dystrophies....
JCM, Vol. 8, Pages 2077: Simultaneous Monitoring of Mutation and Chimerism Using Next-Generation Sequencing in Myelodysplastic Syndrome Journal of Clinical Medicine doi: 10.3390/jcm8122077 Authors: Jong-Mi Lee Yoo-Jin Kim Sung-Soo Park Eunhee Han Myungshin Kim Yonggoo Kim Monitoring minimal residual disease (MRD) provides important information during treatment of hematologic malignancies. Chimerism analysis also provides key information after allogeneic hematopoietic stem...
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JFMK, Vol. 4, Pages 70: Eccentric Resistance Training in Youth: Perspectives for Long-Term Athletic Development Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk4040070 Authors: Drury Ratel Clark Fernandes Moran Behm The purpose of this narrative review is to discuss the role of eccentric resistance training in youth and how this training modality can be utilized within long-term physical development. Current literature on responses to eccentric...
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JoF, Vol. 5, Pages 112: Molecular Diagnostics of Mucormycosis in Hematological Patients: A Literature Review Journal of Fungi doi: 10.3390/jof5040112 Authors: Olga V. Shadrivova Ekaterina V. Burygina Nikolai N. Klimko Objectives: to analyze the results of molecular methods applying for the diagnosis of mucormycosis in hematologic patients based on a literature review. Data sources: A systematic search in databases PubMed, Google Scholar for August 2019. Review eligibility criteria:...
JoF, Vol. 5, Pages 111: Candida auris: A Review of Recommendations for Detection and Control in Healthcare Settings Journal of Fungi doi: 10.3390/jof5040111 Authors: Caceres Forsberg Welsh Sexton Lockhart Jackson Chiller Candida auris is an emerging multidrug-resistant fungal pathogen. Since first reported in 2009, C. auris has caused healthcare outbreaks around the world, often involving high mortality. Identification of C. auris has been a major challenge as...
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Medical Sciences, Vol. 7, Pages 108: Transient Receptor Potential Cation Channels in Cancer Therapy Medical Sciences doi: 10.3390/medsci7120108 Authors: Santoni Maggi Morelli Santoni Marinelli In mammals, the transient receptor potential (TRP) channels family consists of six different families, namely TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPML (mucolipin), TRPP (polycystin), and TRPA (ankyrin), that are strictly connected with cancer cell proliferation,...
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Medicina, Vol. 55, Pages 768: Effects of Epigallocatechin Gallate (EGCG) on Urinary Bladder Urothelial Carcinoma―Next-Generation Sequencing and Bioinformatics Approaches Medicina doi: 10.3390/medicina55120768 Authors: Hsiang-Ying Lee Yi-Jen Chen Wei-An Chang Wei-Ming Li Hung-Lung Ke Wen-Jeng Wu Po-Lin Kuo Background and objectives: Bladder urothelial carcinoma is the most common type of genitourinary cancer. Patients with bladder cancer may have limited treatment efficacy...
Medicina, Vol. 55, Pages 767: The Role of Cardiovascular and Metabolic Comorbidities in the Link between Atrial Fibrillation and Cognitive Impairment: An Appraisal of Current Scientific Evidence Medicina doi: 10.3390/medicina55120767 Authors: Ahmed AlTurki Jakub B. Maj Mariam Marafi Filippo Donato Giovanni Vescovo Vincenzo Russo Riccardo Proietti Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice with implications on long-term outcomes....
Medicina, Vol. 55, Pages 766: Indexes of Angiogenic Activation in Myocardial Samples of Patients with Advanced Chronic Heart Failure Medicina doi: 10.3390/medicina55120766 Authors: Komici Gnemmi Sangiorgi Ricciardolo Rinaldi Di Stefano Eleuteri Background and objectives: Ischemic and idiopathic heart failure are characterized by reactive cardiac fibrosis and impaired vasculogenesis involving pro-angiogenic factors such as angiogenin, angiopoietin-1 (Ang-1), and...
Medicina, Vol. 55, Pages 764: Long Term Results of Modified Intersphincteric Resections for Low Rectal Cancer: A Single Center Experience Medicina doi: 10.3390/medicina55120764 Authors: Butiurca Molnar Copotoiu Botoncea Bud Kovacs Satala Gurzu Background and Objectives: The objective of this article is to evaluate the long-term oncological and functional outcomes following modified intersphincteric resections (ISR) for low rectal cancer. The modified technique...
Medicina, Vol. 55, Pages 765: A View of Human Immunodeficiency Virus Infections in the North-West Region of Romania Medicina doi: 10.3390/medicina55120765 Authors: Jianu Bolboacă Topan Filipescu Jianu Itu-Mureşan Background and objectives: In Romania, the human immunodeficiency virus (HIV) epidemic is almost the same as it is in Central Europe, with some differences; particularity the following one: people with nosocomial HIV infection, also known as Romanian cohort....
Medicina, Vol. 55, Pages 763: Ischemic Muscle Necrosis of Lower Extremities in Peripheral Arterial Disease: The Impact of 99mTc-MDP Scintigraphy on Patient Management Medicina doi: 10.3390/medicina55120763 Authors: Donatas Jocius Donatas Vajauskas Arminas Skrebunas Marijus Gutauskas Algirdas Edvardas Tamosiunas Background and objectives: The objective of this study was to assess the value of a whole-body bone scintigraphy using 99m technetium labelled-methyl diphosphonate...
Medicina, Vol. 55, Pages 762: Pharmacologic and Non-Pharmacologic Interventions for HIV-Neuropathy Pain. A Systematic Review and a Meta-Analysis Medicina doi: 10.3390/medicina55120762 Authors: Aikaterini Amaniti Chrysanthi Sardeli Varvara Fyntanidou Panagiota Papakonstantinou Ioannis Dalakakis Antonios Mylonas Konstantinos Sapalidis Christoforos Kosmidis Athanasios Katsaounis Dimitrios Giannakidis Charilaos Koulouris Zoi Aidoni Nikolaos Michalopoulos Paul...
Medicina, Vol. 55, Pages 761: Increase of MAL-II Binding Alpha2,3-Sialylated Glycan Is Associated with 5-FU Resistance and Short Survival of Cholangiocarcinoma Patients Medicina doi: 10.3390/medicina55120761 Authors: Sasiprapa Wattanavises Atit Silsirivanit Kanlayanee Sawanyawisuth Ubon Cha’on Sakda Waraasawapati Waraporn Saentaweesuk Sukanya Luang Chalongchai Chalermwat Chaisiri Wongkham Sopit Wongkham Background and objectives: Sialylation plays important...
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Membranes, Vol. 9, Pages 161: Reference Electrodes with Polymer-Based Membranes—Comprehensive Performance Characteristics Membranes doi: 10.3390/membranes9120161 Authors: Peter Lingenfelter Bartosz Bartoszewicz Jan Migdalski Tomasz Sokalski Mirosław M. Bućko Robert Filipek Andrzej Lewenstam Several types of liquid membrane and solid-state reference electrodes based on different plastics were fabricated. In the membranes studied, equitransferent organic (QB) and inorganic...
Membranes, Vol. 9, Pages 160: Tangential Flow Filtration for the Concentration of Oncolytic Measles Virus: The Influence of Filter Properties and the Cell Culture Medium Membranes doi: 10.3390/membranes9120160 Authors: Loewe Grein Dieken Weidner Salzig Czermak The therapeutic use of oncolytic measles virus (MV) for cancer treatment requires >108 infectious MV particles per dose in a highly pure form. The concentration/purification of viruses is typically...
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Metabolites, Vol. 9, Pages 294: Insights on Salt Tolerance of Two Endemic Limonium Species from Spain Metabolites doi: 10.3390/metabo9120294 Authors: Sara González-Orenga P. Pablo Ferrer-Gallego Emilio Laguna M. Pilar López-Gresa Maria P. Donat-Torres Mercedes Verdeguer Oscar Vicente Monica Boscaiu We have analysed the salt tolerance of two endemic halophytes of the genus Limonium, with high conservation value. In the present study, seed germination and growth parameters...
Metabolites, Vol. 9, Pages 293: Degradation of Extracellular NAD+ Intermediates in Cultures of Human HEK293 Cells Metabolites doi: 10.3390/metabo9120293 Authors: Veronika Kulikova Konstantin Shabalin Kirill Nerinovski Alexander Yakimov Maria Svetlova Ljudmila Solovjeva Andrey Kropotov Mikhail Khodorkovskiy Marie E. Migaud Mathias Ziegler Andrey Nikiforov Nicotinamide adenine dinucleotide (NAD) is an essential redox carrier, whereas its degradation is a key...
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