Antibiotics, Vol. 9, Pages 46: In vitro Antibiotic and Modulatory Activity of Mesosphaerum suaveolens (L.) Kuntze against Candida strains Antibiotics doi: 10.3390/antibiotics9020046 Authors: Rodrigues Costa Almeida Bezerra Cruz de Freitas da Silva Neto dos Santos Bezerra Morais Braga da Silva Ivaneide Rocha Kamdem Iriti Vitalini Duarte Barros The emergence of fungal resistance to commercial drugs has been a major problem for the...
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Antioxidants, Vol. 9, Pages 113: Potentilla rugulosa Nakai Extract Attenuates Bisphenol A-, S- and F-Induced ROS Production and Differentiation of 3T3-L1 Preadipocytes in the Absence of Dexamethasone Antioxidants doi: 10.3390/antiox9020113 Authors: Choi Lee Lee Sim Kim Lee Endocrine disrupting chemicals (EDCs) disrupt the physiological metabolism, thus playing an important role in the development of obesity. EDCs, the so-called ‘obesogens’, might...
Antioxidants, Vol. 9, Pages 109: Pechiche (Vitex Cymosa Berteo ex Speng), a Nontraditional Fruit from Ecuador, is a Dietary Source of Phenolic Acids and Nutrient Minerals, in Addition to Efficiently Counteracting the Oxidative-Induced Damage in Human Dermal Fibroblasts Antioxidants doi: 10.3390/antiox9020109 Authors: Guevara Valdés-Silverio Granda-Albuja Iturralde Jaramillo-Vivanco Giampieri Santos-Buelga González-Paramás Battino Álvarez-Suarez Pechiche...
Antioxidants, Vol. 9, Pages 112: Outcomes of Peptide Vaccine GV1001 Treatment in a Murine Model of Acute Noise-Induced Hearing Loss Antioxidants doi: 10.3390/antiox9020112 Authors: Lee Han Lee Jung Min Song Koo Noise-induced hearing loss (NIHL) is primarily caused by damage to cochlear hair cells, associated with synaptopathy. The novel cell-penetrating peptide GV1001, an antitumor agent, also has antioxidant and anti-inflammatory effects, and is otoprotective...
Antioxidants, Vol. 9, Pages 110: Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects Antioxidants doi: 10.3390/antiox9020110 Authors: Estébanez Rodriguez Visavadiya Whitehurst Cuevas González-Gallego Huang Reactive oxygen and nitrogen species-mediated cellular aging has been linked to diseases such as atherothrombosis and cancer. Although pentraxin 3 (PTX3) is...
Antioxidants, Vol. 9, Pages 111: The Importance of Oxidative Stress in Determining the Functionality of Mammalian Spermatozoa: A Two-Edged Sword Antioxidants doi: 10.3390/antiox9020111 Authors: Aitken Drevet This article addresses the importance of oxidative processes in both the generation of functional gametes and the aetiology of defective sperm function. Functionally, sperm capacitation is recognized as a redox-regulated process, wherein a low level of reactive oxygen species...
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Atmosphere, Vol. 11, Pages 142: An Automatic Recognition Method for Airflow Field Structures of Convective Systems Based on Single Doppler Radar Data Atmosphere doi: 10.3390/atmos11020142 Authors: Wang Gu Hou Dou Airflow structures within convective systems are important predictors of damaging convective disasters. To automatically recognize different kinds of airflow structures (the convergence, divergence, cyclonic rotation, and anticyclonic rotation) within convective...
Atmosphere, Vol. 11, Pages 141: A Multiscale Tiered Approach to Quantify Contributions: A Case Study of PM2.5 in South Korea During 2010–2017 Atmosphere doi: 10.3390/atmos11020141 Authors: Bae Kim Kim Kim We estimated long-term foreign contributions to the particulate matter of 2.5 μm or less in diameter (PM2.5) concentrations in South Korea with a set of air quality simulations. The Weather Research and Forecasting (WRF)-Sparse Matrix Operator Kernel Emissions (SMOKE)-Community...
Atmosphere, Vol. 11, Pages 140: Analysis of Volatile Organic Compounds during the OCTAVE Campaign: Sources and Distributions of Formaldehyde on Reunion Island Atmosphere doi: 10.3390/atmos11020140 Authors: Rocco Colomb Baray Amelynck Verreyken Borbon Pichon Bouvier Schoon Gros Sarda-Esteve Tulet Metzger Duflot Guadagno Peris Brioude The Oxygenated Compounds in the Tropical Atmosphere: Variability and Exchanges (OCTAVE)...
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Behavioral Sciences, Vol. 10, Pages 43: The Effect of Low-Doses of Caffeine and Taurine on Convulsive Seizure Parameters in Rats Behavioral Sciences doi: 10.3390/bs10020043 Authors: Jailani Mubarak Sarkhouh Al Mahrezi Abdulnabi Naiser Alaradi Alabbad Hassan Kamal Introduction: Caffeine, an adenosine-receptor blocker, is believed to have neuronal excitatory effects, while Taurine, a mammalian amino acid, was shown to have neuroinhibitory effects. Aim:...
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Biology, Vol. 9, Pages 22: Centrifugation Force and Time Alter CASA Parameters and Oxidative Status of Cryopreserved Stallion Sperm Biology doi: 10.3390/biology9020022 Authors: Marzano Moscatelli Di Giacomo Martino Lacalandra Dell’Aquila Maruccio Primiceri Chiriacò Zara Ferramosca Conventional sperm selection techniques used in ARTs rely on centrifugation steps. To date, the different studies reported on the effects of centrifugation on stallion...
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Biomimetics, Vol. 5, Pages 4: Effect of Gravity on the Scale of Compliant Shells Biomimetics doi: 10.3390/biomimetics5010004 Authors: Victor Charpentier Sigrid Adriaenssens Thin shells are found across scales ranging from biological blood cells to engineered large-span roof structures. The engineering design of thin shells used as mechanisms has occasionally been inspired by biomimetic concept generators. The research goal of this paper is to establish the physical limits of scalability...
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Biomolecules, Vol. 10, Pages 193: Exploring Protein Fold Space Biomolecules doi: 10.3390/biom10020193 Authors: Taylor The model of protein folding proposed by Ptitsyn and colleagues involves the accretion of secondary structures around a nucleus. As developed by Efimov, this model also provides a useful way to view the relationships among structures. Although somewhat eclipsed by later databases based on the pairwise comparison of structures, Efimov’s approach provides a guide...
Biomolecules, Vol. 10, Pages 192: Reactivation of VX-Inhibited Human Acetylcholinesterase by Deprotonated Pralidoxime. A Complementary Quantum Mechanical Study Biomolecules doi: 10.3390/biom10020192 Authors: da Silva Pereira LaPlante Kuca Ramalho França In the present work, we performed a complementary quantum mechanical (QM) study to describe the mechanism by which deprotonated pralidoxime (2-PAM) could reactivate human (Homo sapiens sapiens) acetylcholinesterase...
Biomolecules, Vol. 10, Pages 191: Anti-Angiogenic Effects of Phytochemicals on miRNA Regulating Breast Cancer Progression Biomolecules doi: 10.3390/biom10020191 Authors: Varghese Liskova Kubatka Mathews Samuel Büsselberg Several phytochemicals have been identified for their role in modifying miRNA regulating tumor progression. miRNAs modulate the expression of several oncogenes and tumor suppressor genes including the genes that regulate tumor angiogenesis. Hypoxia inducible...
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Brain Sciences, Vol. 10, Pages 69: Beneficial Effect of Foot Plantar Stimulation in Gait Parameters in Individuals with Parkinson’s Disease Brain Sciences doi: 10.3390/brainsci10020069 Authors: Brognara Navarro-Flores Iachemet Serra-Catalá Cauli New treatments based on peripheral stimulation of the sensory-motor system have shown to be promising in rehabilitation strategies for patients with neurological disorders, including Parkinson's disease (PD), especially in regards...
Brain Sciences, Vol. 10, Pages 68: Lemur Tyrosine Kinase 2 (LMTK2) Level Inversely Correlates with Phospho-Tau in Neuropathological Stages of Alzheimer’s Disease Brain Sciences doi: 10.3390/brainsci10020068 Authors: Bencze Szarka Bencs Szabó Módis Aarsland Hortobágyi : Alzheimer’s disease (AD) is the most common neurodegenerative dementia. Mapping the pathomechanism and providing novel therapeutic options have paramount significance. Recent studies...
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Cancers, Vol. 12, Pages 300: EVI1 as a Prognostic and Predictive Biomarker of Clear Cell Renal Cell Carcinoma Cancers doi: 10.3390/cancers12020300 Authors: Palomero Bodnar Mateo Herranz-Ors Espín García-Varelo Jesiotr Ruiz de Garibay Casanovas López Pujana The transcription factor EVI1 plays an oncogenic role in several types of neoplasms by promoting aggressive cancer features. EVI1 contributes to epigenetic regulation and transcriptional control,...
Cancers, Vol. 12, Pages 296: Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells Cancers doi: 10.3390/cancers12020296 Authors: Pakuła Mały Uruski Witucka Bogucka Jaroszewska Makowska Niklas Moszyński Sajdak Tykarski Mikuła-Pietrasik Książek Spontaneous senescence of cancer cells remains a puzzling and poorly understood phenomenon. Here we comprehensively characterize this process in...
Cancers, Vol. 12, Pages 297: Toll-like Receptors from the Perspective of Cancer Treatment Cancers doi: 10.3390/cancers12020297 Authors: Javaid Choi Toll-like receptors (TLRs) represent a family of pattern recognition receptors that recognize certain pathogen-associated molecular patterns and damage-associated molecular patterns. TLRs are highly interesting to researchers including immunologists because of the involvement in various diseases including cancers, allergies, autoimmunity,...
Cancers, Vol. 12, Pages 294: Contralateral Liver Hypertrophy and Oncological Outcome Following Radioembolization with 90Y-Microspheres: A Systematic Review Cancers doi: 10.3390/cancers12020294 Authors: Emrullah Birgin Erik Rasbach Steffen Seyfried Nils Rathmann Steffen J. Diehl Stefan O. Schoenberg Christoph Reissfelder Nuh N. Rahbari Radioembolization with 90Y-microspheres has been reported to induce contralateral liver hypertrophy with simultaneous ipsilateral...
Cancers, Vol. 12, Pages 298: A Comprehensive Picture of Extracellular Vesicles and Their Contents. Molecular Transfer to Cancer Cells Cancers doi: 10.3390/cancers12020298 Authors: Jurj Zanoaga Braicu Lazar Tomuleasa Irimie Berindan-Neagoe Critical processes such as growth, invasion, and metastasis of cancer cells are sustained via bidirectional cell-to-cell communication in tissue complex environments. Such communication involves the secretion of soluble factors...
Cancers, Vol. 12, Pages 299: Ribonucleic Acid Engineering of Dendritic Cells for Therapeutic Vaccination: Ready ‘N Able to Improve Clinical Outcome? Cancers doi: 10.3390/cancers12020299 Authors: Willemen Versteven Peeters Berneman Smits Targeting and exploiting the immune system has become a valid alternative to conventional options for treating cancer and infectious disease. Dendritic cells (DCs) take a central place given their role as key orchestrators of immunity....
Cancers, Vol. 12, Pages 295: Riboflavin-Targeted Drug Delivery Cancers doi: 10.3390/cancers12020295 Authors: Darguzyte Drude Lammers Kiessling Active targeting can improve the retention of drugs and drug delivery systems in tumors, thereby enhancing their therapeutic efficacy. In this context, vitamin receptors that are overexpressed in many cancers are promising targets. In the last decade, attention and research were mainly centered on vitamin B9 (folate) targeting; however,...
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Cells, Vol. 9, Pages 306: Role of TGF- in Skin Chronic Wounds: A Keratinocyte Perspective Cells doi: 10.3390/cells9020306 Authors: Liarte Bernabé-García Nicolás Chronic wounds are characterized for their incapacity to heal within an expected time frame. Potential mechanisms driving this impairment are poorly understood and current hypotheses point to the development of an unbalanced milieu of growth factor and cytokines. Among them, TGF- is considered to promote the broadest...
Cells, Vol. 9, Pages 302: Neuromuscular Activity Induces Paracrine Signaling and Triggers Axonal Regrowth after Injury in Microfluidic Lab-On-Chip Devices Cells doi: 10.3390/cells9020302 Authors: Sala-Jarque Mesquida-Veny Badiola-Mateos Samitier Hervera del Río Peripheral nerve injuries, including motor neuron axonal injury, often lead to functional impairments. Current therapies are mostly limited to surgical intervention after lesion, yet these interventions have...
Cells, Vol. 9, Pages 305: Opposite Macrophage Polarization in Different Subsets of Ovarian Cancer: Observation from a Pilot Study Cells doi: 10.3390/cells9020305 Authors: Vankerckhoven Wouters Mathivet Ceusters Baert Van Hoylandt Gerhardt Vergote Coosemans The role of the innate immune system in ovarian cancer is gaining importance. The relevance of tumor-associated macrophages (TAM) is insufficiently understood. In this pilot project, comprising the...
Cells, Vol. 9, Pages 304: Tissue Engineering in Liver Regenerative Medicine: Insights into Novel Translational Technologies Cells doi: 10.3390/cells9020304 Authors: Heydari Najimi Mirzaei Shpichka Ruoss Farzaneh Montazeri Piryaei Timashev Gramignoli Nussler Baharvand Vosough Organ and tissue shortage are known as a crucially important public health problem as unfortunately a small percentage of patients receive transplants. In the context...
Cells, Vol. 9, Pages 303: Tendon Biomimetic Electrospun PLGA Fleeces Induce an Early Epithelial-Mesenchymal Transition and Tenogenic Differentiation on Amniotic Epithelial Stem Cells Cells doi: 10.3390/cells9020303 Authors: Russo El Khatib di Marcantonio Ancora Wyrwa Mauro Walter Weisser Citeroni Lazzaro Di Federico Berardinelli Cammà Schnabelrauch Barboni Background. The design of tendon biomimetic electrospun fleece with Amniotic...
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Chemosensors, Vol. 8, Pages 10: Label-Free Colorimetric Detection of Urine Glucose Based on Color Fading Using Smartphone Ambient-Light Sensor Chemosensors doi: 10.3390/chemosensors8010010 Authors: Wang Guo Hu Liang Li Zhang Xie In this work, a label-free colorimetric assay was developed for the determination of urine glucose using smartphone ambient-light sensor (ALS). Using horseradish peroxidase—hydrogen peroxide—3,3′,5,5′-tetramethylbenzidine...
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Climate, Vol. 8, Pages 22: Independence of future changes of river runoff in Europe from the pathway to global warming Climate doi: 10.3390/cli8020022 Authors: Mentaschi Alfieri Dottori Cammalleri Bisselink Roo Feyen The outcomes of the 2015 Paris Agreement triggered a number of climate impact assessments, such as for floods and droughts, to focus on future time frames corresponding to the years of reaching specific levels of global warming. Yet, the links between...
Climate, Vol. 8, Pages 20: Scale-Dependent Reliability of Projected Rainfalls over Bangladesh with the PRECIS Model Climate doi: 10.3390/cli8020020 Authors: Mondal Nowreen Sakib The regional climate model, Providing REgional Climates for Impact Studies (PRECIS), has been widely used throughout the world to generate climate change projections for impact studies and adaptations. Its recent application in South Asia also includes the projection of rainfall extremes. In spite of...
Climate, Vol. 8, Pages 21: Forest Contribution to Climate Change Mitigation: Management Oriented to Carbon Capture and Storage Climate doi: 10.3390/cli8020021 Authors: Nunes Meireles Pinto Gomes Almeida Ribeiro Today, climate change is assumed by many researchers and scholars as a certainty and is presented as the biggest challenge humanity has ever faced. It is commonly accepted that anthropogenic greenhouse gas emissions are the main cause that is accelerating the process....
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Diagnostics, Vol. 10, Pages 71: Circulating Anti-Sorting Nexins 16 Antibodies as an Emerging Biomarker of Coronary Artery Disease in Patients with Obstructive Sleep Apnea Diagnostics doi: 10.3390/diagnostics10020071 Authors: Katsumata Terada Matsumura Koshikawa Sakao Tomiyoshi Shinmen Nakamura Kuroda Nagashima Kobayashi Kobayashi Iwadate Zhang Hiwasa Tatsumi Biomarkers are not available for monitoring the onset and progression...
Diagnostics, Vol. 10, Pages 70: The Efficacy of Lactulose for the Treatment of Hyperammonemic Encephalopathy Due to Severe Heart Failure Diagnostics doi: 10.3390/diagnostics10020070 Authors: Narita Amiya Kakuda Kaneko Hatano Komuro Hyperammonemic encephalopathy secondary to heart failure is rare and there had been little reports about effective treatment. Organ hypoperfusion or congestion by heart failure may lead to various organ dysfunctions, and liver and intestinal...
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Diversity, Vol. 12, Pages 48: Genetic Structure and Connectivity of the Red Mangrove at Different Geographic Scales through a Complex Transverse Hydrological System from Freshwater to Marine Ecosystems Diversity doi: 10.3390/d12020048 Authors: Chablé Iuit Machkour-M'Rabet Espinoza-Ávalos Hernández-Arana López-Adame Hénaut Mangrove forests are ecologically and economically valuable resources composed of trees morphologically and physiologically adapted to thrive across...
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Foods, Vol. 9, Pages 132: Food Supply Chain and Business Model Innovation Foods doi: 10.3390/foods9020132 Authors: Nosratabadi Mosavi Lakner This paper investigates the contribution of business model innovations in the advancement of novel food supply chains. Through a systematic literature review, the notable business model innovations in the food industry are identified, surveyed, and evaluated. Findings reveal that the innovations in value proposition, value creation processes,...
Foods, Vol. 9, Pages 131: Non-Starch Polysaccharides in Wheat Beers and Barley Malt beers: A Comparative Study Foods doi: 10.3390/foods9020131 Authors: Li Du Zheng Non-starch polysaccharides (NSPs) in beers attract extensive attention due to their health benefits. The aim of this work was to investigate and compare NSPs including arabinoxylan, arabinogalactan, β–glucans, and mannose polymers in wheat and barley malt beers as well as the influence on its quality....
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IJERPH, Vol. 17, Pages 786: Spatial Modelling to Inform Public Health Based on Health Surveys: Impact of Unsampled Areas at Lower Geographical Scale International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030786 Authors: Kevin Watjou Christel Faes Yannick Vandendijck Small area estimation is an important tool to provide area-specific estimates of population characteristics for governmental organizations in the context of education, public health and...
IJERPH, Vol. 17, Pages 788: Coupling of kenaf Biochar and Magnetic BiFeO3 onto Cross-linked Chitosan for Enhancing Separation Performance and Cr(VI) Ions Removal Efficiency International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030788 Authors: Zhou Xie Hu Cai Zhao Hu Jin Fu Tan Liang Lai Wang Tang Cr(VI) contamination has posed great threat to both the ecosystem and human health for its carcinogenic and...
IJERPH, Vol. 17, Pages 787: Expired Medication: Societal, Regulatory and Ethical Aspects of a Wasted Opportunity International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030787 Authors: Alnahas Yeboah Fliedel Abdin Alhareth A massive volume of expired medications amasses annually around the world because of pharmaceutical overprescription, combined with overproduction. The accumulation of pharmaceutical waste imposes ecological, economic...
IJERPH, Vol. 17, Pages 784: Effect of Alkalinity on Catalytic Activity of Iron–Manganese Co-oxide in Removing Ammonium and Manganese: Performance and Mechanism International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030784 Authors: Cheng Zhang Huang Hu Gao Niu In this study, a pilot-scale experimental filter system was used to investigate the effect of bicarbonate alkalinity on the activity of an Fe–Mn co-oxide for ammonium...
IJERPH, Vol. 17, Pages 782: Diagnosis-Specific Sickness Absence and Subsequent Common Mental Disorders: A Register-Linkage Cohort Study among Finnish Public Sector Employees International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030782 Authors: Mauramo Lallukka Mänty Sumanen Pietiläinen Lahelma Rahkonen Sickness absence is associated with poor health outcomes, but little is known about its consequences for general mental health....
IJERPH, Vol. 17, Pages 778: Social Support and Subclinical Coronary Artery Disease in Middle-Aged Men and Women: Findings from the Pilot of Swedish CArdioPulmonary bioImage Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030778 Authors: Djekic Fagman Angerås Lappas Torén Bergström Rosengren Social support has been associated with coronary artery disease (CAD), particularly in individuals who have sustained a cardiovascular...
IJERPH, Vol. 17, Pages 781: Deficit Alternate Drip Irrigation Increased Root-Soil-Plant Interaction, Tomato Yield, and Quality International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030781 Authors: Wang Li Niu To determine the soil mechanism in root-zone caused by water saving and the production response to alternate drip irrigation (ADI), the present study investigated the effects of deficit ADI on tomato growth using the conventional surface...
IJERPH, Vol. 17, Pages 779: Patterns of Bullying Victimization and Associations with Mental Health Problems in Chinese Adolescents: A Latent Class Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030779 Authors: Zhang Gong Li Wang Wu Guo Lu Bullying victimization in school students is a serious public health concern and has been linked to a wide range of mental health problems. The current study aims to examine patterns...
IJERPH, Vol. 17, Pages 783: Health Behaviors and Psychological Distress Among Conscripts of the Lithuanian Military Service: A Nationally Representative Cross-Sectional Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030783 Authors: Mieziene Emeljanovas Cesnaitiene Vizbaraite Zumbakyte-Sermuksniene The decline in healthy behavior in young people is a concern for public health in general and for country’s defense....
IJERPH, Vol. 17, Pages 785: Methodological Quality of Manuscripts Reporting on the Usability of Mobile Applications for Pain Assessment and Management: A Systematic Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030785 Authors: Almeida Rocha Silva Background: There has been increasing use of mobile mHealth applications, including pain assessment and pain self-management apps. The usability of mHealth applications has vital importance...
IJERPH, Vol. 17, Pages 780: Association between Dental Amalgam Filling and Essential Tremor: A Nationwide Population-Based Case Control Study in Taiwan International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17030780 Authors: Tseng Chen Yu Chang Essential tremor (ET) is a common neurological disorder and the most common movement disorder. Low-level occupational exposure to mercury vapor is known to be a crucial factor that increases the risk...
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IJMS, Vol. 21, Pages 823: Myoblast Migration and Directional Persistence Affected by Syndecan-4-Mediated Tiam-1 Expression and Distribution International Journal of Molecular Sciences doi: 10.3390/ijms21030823 Authors: Becsky Gyulai-Nagy Balind Horvath Dux Keller-Pinter Skeletal muscle is constantly renewed in response to injury, exercise, or muscle diseases. Muscle stem cells, also known as satellite cells, are stimulated by local damage to proliferate extensively...
IJMS, Vol. 21, Pages 821: Reciprocal Regulatory Interaction between TRPV1 and Kinin B1 Receptor in a Rat Neuropathic Pain Model International Journal of Molecular Sciences doi: 10.3390/ijms21030821 Authors: Cernit Sénécal Othman Couture Kinins are mediators of pain and inflammation and evidence suggests that the inducible kinin B1 receptor (B1R) is involved in neuropathic pain (NP). This study investigates whether B1R and TRPV1 are colocalized on nociceptors and/or astrocytes...
IJMS, Vol. 21, Pages 822: miR-21-KO Alleviates Alveolar Structural Remodeling and Inflammatory Signaling in Acute Lung Injury International Journal of Molecular Sciences doi: 10.3390/ijms21030822 Authors: Jansing Fiedler Pich Viereck Thum Mühlfeld Brandenberger : Acute lung injury (ALI) is characterized by enhanced permeability of the air–blood barrier, pulmonary edema, and hypoxemia. MicroRNA-21 (miR-21) was shown to be involved in pulmonary remodeling...
IJMS, Vol. 21, Pages 820: Circadian Rhythms in Exudative Age-Related Macular Degeneration: The Key Role of the Canonical WNT/β-Catenin Pathway International Journal of Molecular Sciences doi: 10.3390/ijms21030820 Authors: Vallée Lecarpentier Vallée Guillevin Vallée : Age-related macular degeneration (AMD) is considered as the main worldwide cause of blindness in elderly adults. Exudative AMD type represents 10 to 15% of macular degeneration cases, but is the main cause...
IJMS, Vol. 21, Pages 819: GAI Functions in the Plant Response to Dehydration Stress in Arabidopsis thaliana International Journal of Molecular Sciences doi: 10.3390/ijms21030819 Authors: Wang Liu Cheng Ren Xu Li DELLA (GAI/RGA/RGL1/RGL2/RGL3) proteins are key negative regulators in GA (gibberellin) signaling and are involved in regulating plant growth as a response to environmental stresses. It has been shown that the DELLA protein PROCERA (PRO) in tomato promotes...
IJMS, Vol. 21, Pages 818: Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria International Journal of Molecular Sciences doi: 10.3390/ijms21030818 Authors: Noriyuki Akahoshi Tatsuro Minakawa Masashi Miyashita Uran Sugiyama Chihiro Saito Rintaro Takemoto Akihiro Honda Waka Kamichatani Shotaro Kamata Yasumi Anan Isao Ishii ...
IJMS, Vol. 21, Pages 817: Role of Phagocytosis in the Pro-Inflammatory Response in LDL-Induced Foam Cell Formation; a Transcriptome Analysis International Journal of Molecular Sciences doi: 10.3390/ijms21030817 Authors: Orekhov Nikiforov Sukhorukov Kubekina Sobenin Wu Foxx Pintus Stegmaier Stelmashenko Kel Gratchev Melnichenko Wetzker Summerhill Manabe Oishi Excessive accumulation of lipid inclusions in the arterial wall...
IJMS, Vol. 21, Pages 814: Adenosine Suppresses Cholangiocarcinoma Cell Growth and Invasion in Equilibrative Nucleoside Transporters and Proline-Rich Homeodomain Protein-Dependent Pathway International Journal of Molecular Sciences doi: 10.3390/ijms21030814 Authors: Kornkamon Lertsuwan Supathra Phoaubon Nathapol Tasnawijitwong Jomnarong Lertsuwan Cholangiocarcinoma (CCA) is a lethal disease with increasing incidence worldwide. Previous study showed that CCA was sensitive to adenosine....
IJMS, Vol. 21, Pages 815: Salivary Immunoglobulin A Secretion and Polymeric Ig Receptor Expression in the Submandibular Glands Are Enhanced in Heat-Acclimated Rats International Journal of Molecular Sciences doi: 10.3390/ijms21030815 Authors: Matsuzaki Sugimoto Islam Hossain Sumiyoshi Katakura Shido Salivary immunoglobulin A (IgA) plays a critical role in mucosal immunity. Chronic exposure to moderate heat induces heat acclimation, which modifies salivary functions....
IJMS, Vol. 21, Pages 813: Resveratrol as Inducer of Autophagy, Pro-Survival, and Anti-Inflammatory Stimuli in Cultured Human RPE Cells International Journal of Molecular Sciences doi: 10.3390/ijms21030813 Authors: Josifovska Albert Nagymihály Lytvynchuk Moe Kaarniranta Veréb Petrovski Purpose: To investigate the mechanism by which resveratrol acts upon retinal pigment epithelial (RPE) cells and to characterize its effect upon autophagy, survival, and inflammation,...
IJMS, Vol. 21, Pages 816: Microglial Activation in the Retina of a Triple-Transgenic Alzheimer’s Disease Mouse Model (3xTg-AD) International Journal of Molecular Sciences doi: 10.3390/ijms21030816 Authors: Elena Salobrar-García Ana C. Rodrigues-Neves Ana I. Ramírez Rosa de Hoz José A. Fernández-Albarral Inés López-Cuenca José M. Ramírez António F. Ambrósio Juan J. Salazar Alzheimer’s disease (AD) is the most common type of dementia in the world. The...
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JCDD, Vol. 7, Pages 5: Sarcopenic Obesity Predicts Early Attrition in Treatment-Seeking Patients with Obesity: A Longitudinal Pilot Study Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd7010005 Authors: Kreidieh Itani Tannir El Masri El Ghoch Attrition is a major cause of failure in obesity treatment, which is still not fully understood. The identification of factors related to this outcome is of clinical relevance. We aimed to assess the relationship...
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JCM, Vol. 9, Pages 354: Title: Human Serum/Plasma Glycoprotein Analysis by 1H-NMR, an Emerging Method of Inflammatory Assessment Journal of Clinical Medicine doi: 10.3390/jcm9020354 Authors: Fuertes-Martín Correig Vallvé Amigó Several studies suggest that variations in the concentration of plasma glycoproteins can influence cellular changes in a large number of diseases. In recent years, proton nuclear magnetic resonance (1H-NMR) has played a major role as an analytical...
JCM, Vol. 9, Pages 346: The Coming Age of Flavonoids in the Treatment of Diabetic Complications Journal of Clinical Medicine doi: 10.3390/jcm9020346 Authors: Caro-Ordieres Marín-Royo Opazo-Ríos Jiménez-Castilla Moreno Gómez-Guerrero Egido Diabetes mellitus (DM), and its micro and macrovascular complications, is one of the biggest challenges for world public health. Despite overall improvement in prevention, diagnosis and treatment, its incidence is expected to...
JCM, Vol. 9, Pages 353: Looking for a Better Characterization of Triple-Negative Breast Cancer by Means of Circulating Tumor Cells Journal of Clinical Medicine doi: 10.3390/jcm9020353 Authors: Abreu Cabezas-Sainz Pereira-Veiga Falo Abalo Morilla Curiel Cueva Rodríguez Varela-Pose Lago-Lestón Mondelo Palacios Moreno-Bueno Cano García-Caballero Pujana Sánchez-Piñón Costa López Muinelo-Romay Traditionally,...
JCM, Vol. 9, Pages 347: Working Alliance in Blended Versus Face-to-Face Cognitive Behavioral Treatment for Patients with Depression in Specialized Mental Health Care Journal of Clinical Medicine doi: 10.3390/jcm9020347 Authors: Kooistra Ruwaard Wiersma van Oppen Riper This study investigates working alliance in blended cognitive behavioral therapy (bCBT) for depressed adults in specialized mental health care. Patients were randomly allocated to bCBT (n = 47) or face-to-face...
JCM, Vol. 9, Pages 348: A Collaborative Medication Review Including Deprescribing for Older Patients in an Emergency Department: A Longitudinal Feasibility Study Journal of Clinical Medicine doi: 10.3390/jcm9020348 Authors: Houlind Andersen Treldal Jørgensen Kannegaard Castillo Christensen Tavenier Rasmussen Ankarfeldt Andersen Petersen Medication review for older patients with polypharmacy in the emergency department (ED) is crucial to prevent...
JCM, Vol. 9, Pages 349: Seasonal Variation in Physical Activity among Preoperative Patients with Lung Cancer Determined Using a Wearable Device Journal of Clinical Medicine doi: 10.3390/jcm9020349 Authors: Kong Park Kang Lee Lee Kwon Shim Zo Cho We aim to examine how season and temperature levels affect physical activity using a wearable device among patients scheduled to undergo surgical resection of lung cancer. Physical activity (PA) data from the...
JCM, Vol. 9, Pages 352: Lack in Periodontal Care of Patients Suffering from Severe Heart Diseases—Results after 12 Months Follow-Up Journal of Clinical Medicine doi: 10.3390/jcm9020352 Authors: Ziebolz Friedrich Binner Rast Eisner Wagner Schmickler Kottmann Haak Borger Lehmann Oberbach Garbade Schmalz Background: To assess whether the standardized recommendation of patients with heart failure (HF), left-ventricular assist device (LVAD)...
JCM, Vol. 9, Pages 344: Molecular Bases of Neurodegeneration and Cognitive Decline, the Major Burden of Sanfilippo Disease Journal of Clinical Medicine doi: 10.3390/jcm9020344 Authors: Heon-Roberts Nguyen Pshezhetsky The mucopolysaccharidoses (MPS) are a group of diseases caused by the lysosomal accumulation of glycosaminoglycans, due to genetic deficiencies of enzymes involved in their degradation. MPS III or Sanfilippo disease, in particular, is characterized by early-onset...
JCM, Vol. 9, Pages 351: Biomarker-Based Preoperative Risk Stratification for Patients Undergoing Non-Cardiac Surgery Journal of Clinical Medicine doi: 10.3390/jcm9020351 Authors: Yurttas Hidvegi Filipovic Perioperative morbidity and mortality remains a substantial problem and is strongly associated with patients’ cardiac comorbidities. Guidelines for the cardiovascular assessment and management of patients at risk of cardiac issues while undergoing non-cardiac surgery...
JCM, Vol. 9, Pages 345: Postprandial Hypotension as a Risk Factor for the Development of New Cardiovascular Disease: A Prospective Cohort Study with 36 Month Follow-Up in Community-Dwelling Elderly People Journal of Clinical Medicine doi: 10.3390/jcm9020345 Authors: Jang Postprandial hypotension (PPH) is common among the elderly. However, it is unknown whether the presence of PPH can predict the development of new cardiovascular disease (CVD) in the elderly during the long-term period....
JCM, Vol. 9, Pages 350: Activated Clotting Time Monitoring during Atrial Fibrillation Catheter Ablation: Does the Anticoagulant Matter? Journal of Clinical Medicine doi: 10.3390/jcm9020350 Authors: Martin Kyheng Foissaud Duhamel Marijon Susen Godier Atrial fibrillation (AF) catheter ablation is performed in patients receiving direct oral anticoagulants (DOACs) with intra-procedural unfractionated heparin (UFH) administration to achieve activated clotting time...
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JoF, Vol. 6, Pages 18: Blood Aspergillus PCR: The Good, the Bad, and the Ugly Journal of Fungi doi: 10.3390/jof6010018 Authors: Egger Jenks Hoenigl Prattes Invasive Aspergillosis (IA) is one of the most common invasive fungal diseases and is accompanied by high morbidity and mortality. In order to maximize patient outcomes and survival, early and rapid diagnosis has been shown to be pivotal. Hence, diagnostic tools aiding and improving the diagnostic process are ambitiously...
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Medical Sciences, Vol. 8, Pages 7: The Potential Role of Astrocytes in Parkinson’s Disease (PD) Medical Sciences doi: 10.3390/medsci8010007 Authors: Hiluf Hindeya Gebreyesus Teklu Gebrehiwot Gebremichael Astrocytes are multi-functional cells, now recognized as critical participants in many brain functions. They play a critical physiological role in the clearance of neurotransmitters, such as glutamate and gamma-aminobutyric acid (GABA), and in the regulation of K+ from the space of...
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Medicina, Vol. 56, Pages 53: Dental Implants in Patients with Oral Lichen Planus: A Systematic Review Medicina doi: 10.3390/medicina56020053 Authors: Chrcanovic Cruz Trindade Gomez Background and Objectives: To integrate the available published data on patients with oral lichen planus (OLP) rehabilitated with dental implants, as well as to review the recommendations for OLP patients receiving implants. Materials and Methods: An electronic search was undertaken in February...
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Membranes, Vol. 10, Pages 20: Characterization of MK-40 Membrane Modified by Layers of Cation Exchange and Anion Exchange Polyelectrolytes Membranes doi: 10.3390/membranes10020020 Authors: Titorova Sabbatovskiy Sarapulova Kirichenko Sobolev Kirichenko Coating of ion exchange membranes used in electrodialysis with layers of polyelectrolytes is a proven approach that allows for the increasing of the limiting current, the suppressing of sedimentation, the controlling...
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Metabolites, Vol. 10, Pages 48: Metabolically Healthy Obesity—Heterogeneity in Definitions and Unconventional Factors Metabolites doi: 10.3390/metabo10020048 Authors: Brandão Martins Monteiro The concept of heterogeneity among obese individuals in their risk for developing metabolic dysfunction and associated complications has been recognized for decades. At the origin of the heterogeneity idea is the acknowledgement that individuals with central obesity are more prone to developing...
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Microorganisms, Vol. 8, Pages 179: Prenatal and Peripartum Exposure to Antibiotics and Cesarean Section Delivery Are Associated with Differences in Diversity and Composition of the Infant Meconium Microbiome Microorganisms doi: 10.3390/microorganisms8020179 Authors: Wendy S.W. Wong Priya Sabu Varsha Deopujari Shira Levy Ankit A. Shah Nicole Clemency Marina Provenzano Reem Saadoon Akhil Munagala Robin Baker Rajiv Baveja Noel T. Mueller Maria Gloria Dominguez-Bello...
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