IJMS, Vol. 21, Pages 919: Metabolic Profiling in Blastocoel Fluid and Blood Plasma of Diabetic Rabbits International Journal of Molecular Sciences doi: 10.3390/ijms21030919 Authors: Schindler Pendzialek Grybel Seeling Navarrete Santos Metabolic disorders of the mother adversely affect early embryo development, causing changes in maternal metabolism and consequent alterations in the embryo environment in the uterus. The goal of this study was to analyse the biochemical...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 920: Oral Intake of EPA:DHA 6:1 by Middle-Aged Rats for One Week Improves Age-Related Endothelial Dysfunction in Both the Femoral Artery and Vein: Role of Cyclooxygenases International Journal of Molecular Sciences doi: 10.3390/ijms21030920 Authors: Gaertner Auger Farooq Pollet Khemais-Benkhiat Niazi Schrevens Park Toti Stephan Schini-Kerth In humans, aging is associated with endothelial dysfunction and an increased risk of...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 921: Dormancy-Associated MADS-Box (DAM) Genes Influence Chilling Requirement of Sweet Cherries and Co-Regulate Flower Development with SOC1 Gene International Journal of Molecular Sciences doi: 10.3390/ijms21030921 Authors: Jiyuan Wang Zhen Gao Hui Li Songtao Jiu Yueting Qu Lei Wang Chao Ma Wenping Xu Shiping Wang Caixi Zhang Floral bud dormancy release of fruit tree species is greatly influenced by climate change. The lack of chilling...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 911: Functional Analysis of Long Non-Coding RNAs Reveal Their Novel Roles in Biocontrol of Bacteria-Induced Tomato Resistance to Meloidogyne incognita International Journal of Molecular Sciences doi: 10.3390/ijms21030911 Authors: Fan Yang Dan Zhao Haiyan Fan Xiaofeng Zhu Yuanyuan Wang Xiaoyu Liu Yuxi Duan Yuanhu Xuan Lijie Chen Root-knot nematodes (RKNs) severely affect plants growth and productivity, and several commercial biocontrol bacteria...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 896: Comparison of Eight Technologies to Determine Genotype at the UGT1A1 (TA)n Repeat Polymorphism: Potential Clinical Consequences of Genotyping Errors? International Journal of Molecular Sciences doi: 10.3390/ijms21030896 Authors: Sissung Barbier Price Plona Pike Mellott Baugher Whiteley Soppet Venzon Berman Rajan Giaccone Meltzer Figg To ensure accuracy of UGT1A1 (TA)n (rs3064744) genotyping for use in...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 899: NOD-like Receptors in the Eye: Uncovering Its Role in Diabetic Retinopathy
IJMS, Vol. 21, Pages 899: NOD-like Receptors in the Eye: Uncovering Its Role in Diabetic Retinopathy International Journal of Molecular Sciences doi: 10.3390/ijms21030899 Authors: Rayne R. Lim Margaret E. Wieser Rama R. Ganga Veluchamy A. Barathi Rajamani Lakshminarayanan Rajiv R. Mohan Dean P. Hainsworth Shyam S. Chaurasia Diabetic retinopathy (DR) is an ocular complication of diabetes mellitus (DM). International Diabetic Federations (IDF) estimates up to 629 million...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 900: A Unique Regulation Region in the 3′ UTR of HLA-G with a Promising Potential International Journal of Molecular Sciences doi: 10.3390/ijms21030900 Authors: Reches Berhani Mandelboim Human leukocyte antigen G (HLA-G) is a non-classical human leukocyte antigen (HLA) class I protein that interacts with inhibitory receptors and is commonly overexpressed in various cancers, thereby establishing itself as an inhibitory checkpoint immune ligand. It is also...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 901: BMAL1 Modulates Epidermal Healing in a Process Involving the Antioxidative Defense Mechanism International Journal of Molecular Sciences doi: 10.3390/ijms21030901 Authors: Silveira Nascimento Filho Yujra Webber Castilho Squarize The circadian rhythm regulates the physiology and behavior of living organisms in a time-dependent manner. Clock genes have distinct roles including the control over gene expression mediated by the transcriptional...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 902: Expression of Bitter Taste Receptors in the Intestinal Cells of Non-Human Primates International Journal of Molecular Sciences doi: 10.3390/ijms21030902 Authors: Imai Hakukawa Hayashi Iwatsuki Masuda (1) Background: Recent studies have investigated the expression of taste-related genes in the organs of various animals, including humans; however, data for additional taxa are needed to facilitate comparative analyses within and among species....
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 903: ADAM12 is A Potential Therapeutic Target Regulated by Hypomethylation in Triple-Negative Breast Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21030903 Authors: Saioa Mendaza Ane Ulazia-Garmendia Iñaki Monreal-Santesteban Alicia Córdoba Yerani Ruiz de Azúa Begoña Aguiar Raquel Beloqui Pedro Armendáriz Marta Arriola Esperanza Martín-Sánchez David Guerrero-Setas Triple-negative breast cancer (TNBC) is the most...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 905: Engineering Prostate Cancer from Induced Pluripotent Stem Cells—New Opportunities to Develop Preclinical Tools in Prostate and Prostate Cancer Studies International Journal of Molecular Sciences doi: 10.3390/ijms21030905 Authors: Hepburn Sims Buskin Heer One of the key issues hampering the development of effective treatments for prostate cancer is the lack of suitable, tractable, and patient-specific in vitro models that accurately recapitulate...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 906: In Vitro Evaluation of Different Prebiotics on the Modulation of Gut Microbiota Composition and Function in Morbid Obese and Normal-Weight Subjects International Journal of Molecular Sciences doi: 10.3390/ijms21030906 Authors: Nogacka Salazar Arboleya Ruas-Madiedo Mancabelli Suarez Martinez-Faedo Ventura Tochio Hirano Endo de los Reyes-Gavilán Gueimonde The gut microbiota remains relatively stable during adulthood;...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 907: Salivary MicroRNA for Diagnosis of Cancer and Systemic Diseases: A Systematic Review International Journal of Molecular Sciences doi: 10.3390/ijms21030907 Authors: Setti Pezzi Viani Pertinhez Cassi Magnoni Bellini Musolino Vescovi Meleti : Background: The aberrant expression of microRNAs (miRNAs) has been associated with several diseases, including cancer, inflammatory, and autoimmune conditions. Interest in salivary miRNAs...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 908: Dendritic Spines in Alzheimer’s Disease: How the Actin Cytoskeleton Contributes to Synaptic Failure International Journal of Molecular Sciences doi: 10.3390/ijms21030908 Authors: Pelucchi Stringhi Marcello Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by Aβ-driven synaptic dysfunction in the early phases of pathogenesis. In the synaptic context, the actin cytoskeleton is a crucial element to maintain the dendritic...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 909: Combined Proteomics and Metabolism Analysis Unravels Prominent Roles of Antioxidant System in the Prevention of Alfalfa (Medicago sativa L.) against Salt Stress International Journal of Molecular Sciences doi: 10.3390/ijms21030909 Authors: Li Essemine Shang Zhang Zhu Yu Chen Qu Sun Alfalfa is the most extensively cultivated forage legume worldwide, and salinity constitutes the main environmental scourge limiting its growth and...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 904: Impact and Intricacies of Bone Marrow Microenvironment in B-cell Lymphomas: From Biology to Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21030904 Authors: Anuvrat Sircar Sayan Mullick Chowdhury Amber Hart William Connor Bell Satishkumar Singh Lalit Sehgal Narendranath Epperla Lymphoma, a group of widely prevalent hematological malignancies of lymphocyte origin, has become the focus of significant clinical research due...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 910: Controversial Roles of Gut Microbiota-Derived Short-Chain Fatty Acids (SCFAs) on Pancreatic β-Cell Growth and Insulin Secretion International Journal of Molecular Sciences doi: 10.3390/ijms21030910 Authors: Jun-Li Liu Irina Segovia Xiao-Lin Yuan Zu-hua Gao In the past 15 years, gut microbiota emerged as a crucial player in health and disease. Enormous progress was made in the analysis of its composition, even in the discovery of novel species. It is...
Thu Jan 30, 2020 02:00
IJMS, Vol. 21, Pages 861: Comparative Transcriptome Analysis of Different Dendrobium Species Reveals Active Ingredients-Related Genes and Pathways International Journal of Molecular Sciences doi: 10.3390/ijms21030861 Authors: Yingdan Yuan Bo Zhang Xinggang Tang Jinchi Zhang Jie Lin Dendrobium is widely used in traditional Chinese medicine, which contains many kinds of active ingredients. In recent years, many Dendrobium transcriptomes have been sequenced. Hence, weighted...
Wed Jan 29, 2020 02:00
JCM, Vol. 9, Pages 378: Contemporary Speech and Oral Language Care for Deaf and Hard-of-Hearing Children Using Hearing Devices Journal of Clinical Medicine doi: 10.3390/jcm9020378 Authors: Bergeron Berland Demers Gobeil Contemporary speech and language interventions are not limited to disabilities but embrace the pragmatics of communication behaviors from the perspective of functional social participation. Accordingly, current speech and language therapies for deaf and hard-of-hearing...
Thu Jan 30, 2020 02:00
JCM, Vol. 9, Pages 377: Saliva Diagnosis as a Disease Predictor Journal of Clinical Medicine doi: 10.3390/jcm9020377 Authors: McGeer Lee Kennedy McGeer Background: Saliva, the most readily available body fluid, is the product of genes which are in constant activity throughout life. Measurement of saliva can predict the onset of some diseases years before their accumulation in vulnerable tissues causes clinical signs to appear. The purpose of this study was is to demonstrate...
Thu Jan 30, 2020 02:00
JCM, Vol. 9, Pages 376: Saharan Dust Events in the Dust Belt -Canary Islands- and the Observed Association with in-Hospital Mortality of Patients with Heart Failure Journal of Clinical Medicine doi: 10.3390/jcm9020376 Authors: Alberto Dominguez-Rodriguez Néstor Baez-Ferrer Sergio Rodríguez Pablo Avanzas Pedro Abreu-Gonzalez Enric Terradellas Emilio Cuevas Sara Basart Ernest Werner Recent studies have found increases in the cardiovascular mortality rates during...
Thu Jan 30, 2020 02:00
JFMK, Vol. 5, Pages 10: Exercise Prescription in Renal Transplant Recipients: From Sports Medicine Toward Multidisciplinary Aspects: A Pilot Study Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5010010 Authors: Orlandi Sofi Moscarelli Cirami Mancini Stefani Renal transplantation is the choice treatment for end-stage renal disease. In spite of transplantation, cardiovascular morbidity and mortality remains high, possibly due to a prolonged sedentary...
Thu Jan 30, 2020 02:00
Membranes, Vol. 10, Pages 21: Mitigation of Membrane Fouling Using an Electroactive Polyether Sulfone Membrane Membranes doi: 10.3390/membranes10020021 Authors: Chunyan Ma Chao Yi Fang Li Chensi Shen Zhiwei Wang Wolfgang Sand Yanbiao Liu Membrane fouling is the bottleneck limiting the wide application of membrane processes. Herein, we adopted an electroactive polyether sulfone (PES) membrane capable of mitigating fouling by various negatively charged foulants. To evaluate...
Thu Jan 30, 2020 02:00
Metabolites, Vol. 10, Pages 55: Identification of the Main Metabolites of a Marine-Derived Strain of Penicillium brevicompactum Using LC and GC MS Techniques Metabolites doi: 10.3390/metabo10020055 Authors: Vinale Salvatore Nicoletti Staropoli Manganiello Venneri Borrelli DellaGreca Salvatore Andolfi Marine-derived fungi are an important source of many valuable compounds with original structures and diverse physico-chemical properties. In this work,...
Thu Jan 30, 2020 02:00
Metabolites, Vol. 10, Pages 54: General Guidelines for Sample Preparation Strategies in HR-µMAS NMR-based Metabolomics of Microscopic Specimens Metabolites doi: 10.3390/metabo10020054 Authors: Lucas-Torres Bernard Huber Berthault Nishiyama Kandiyal Elena-Herrmann Molin Solari Bouzier-Sore Wong The study of the metabolome within tissues, organisms, cells or biofluids can be carried out by several bioanalytical techniques. Among them, nuclear magnetic...
Thu Jan 30, 2020 02:00
Microorganisms, Vol. 8, Pages 191: Emerging Treatment Options for Infections by Multidrug-Resistant Gram-Positive Microorganisms Microorganisms doi: 10.3390/microorganisms8020191 Authors: Koulenti Xu Song Sum Mok Karageorgopoulos Armaganidis Tsiodras Lipman Antimicrobial agents are currently the mainstay of treatment for bacterial infections worldwide. However, due to the increased use of antimicrobials in both human and animal medicine, pathogens have now...
Thu Jan 30, 2020 02:00
Microorganisms, Vol. 8, Pages 190: Keystone Species and Modularity in Microbial Hydrocarbon Degradation Uncovered by Network Analysis and Association Rule Mining Microorganisms doi: 10.3390/microorganisms8020190 Authors: Centler Günnigmann Fetzer Wendeberg Natural microbial communities in soils are highly diverse, allowing for rich networks of microbial interactions to unfold. Identifying key players in these networks is difficult as the distribution of microbial diversity...
Thu Jan 30, 2020 02:00
Microorganisms, Vol. 8, Pages 192: A Big World in Small Grain: A Review of Natural Milk Kefir Starters Microorganisms doi: 10.3390/microorganisms8020192 Authors: Nejati Junne Neubauer Milk kefir is a traditional fermented milk product whose consumption is becoming increasingly popular. The natural starter for kefir production is kefir grain, which consists of various bacterial and yeast species. At the industrial scale, however, kefir grains are rarely used due to their slow...
Thu Jan 30, 2020 02:00
Molbank, Vol. 2020, Article M1114: (E)-(1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline: Synthesis, Characterization, DNA-Interaction, and Evaluation of Activity Against Drug-Resistant Cell Lines Molbank doi: 10.3390/M1114 Authors: Matiadis Mavroidi Panagiotopoulou Methenitis Pelecanou Sagnou (E)-1-(4-Ethoxycarbonylphenyl)-5-(3,4-dimethoxyphenyl)-3-(3,4-dimethoxystyryl)-2-pyrazoline was synthesized via the cyclization reaction...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 615: Laser-Plasma Spatiotemporal Cyanide Spectroscopy and Applications Molecules doi: 10.3390/molecules25030615 Authors: Christian G. Parigger Christopher M. Helstern Benjamin S. Jordan David M. Surmick Robert Splinter This article reports new measurements of laser-induced plasma hypersonic expansion measurements of diatomic molecular cyanide (CN). Focused, high-peak-power 1064 nm Q-switched radiation of the order of 1 TW/cm 2 generated optical...
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Molecules, Vol. 25, Pages 616: Differences in Production, Composition, and Antioxidant Activities of Exopolymeric Substances (EPS) Obtained from Cultures of Endophytic Fusarium culmorum Strains with Different Effects on Cereals Molecules doi: 10.3390/molecules25030616 Authors: Jaroszuk-Ściseł Nowak Komaniecka Choma Jarosz-Wilkołazka Osińska-Jaroszuk Tyśkiewicz Wiater Rogalski Exopolymeric substances (EPS) can determine plant-microorganism interactions...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 612: Selective Chromogenic Recognition of Copper(II) Ion by Thiacalix[4]arene Tetrasulfonate and Mechanism Molecules doi: 10.3390/molecules25030612 Authors: Zhu Lu Detection of biologically important transition metal ions such as copper by using a simple method is desirable and of great importance. In this work, we firstly reported that water-soluble thiacalix[4]arene tetrasulfonate (TCAS) exhibited selective chromogenic recognition towards copper(II) ion...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 614: Technological Application of Tannin-Based Extracts Molecules doi: 10.3390/molecules25030614 Authors: Maria Fraga-Corral Paula García-Oliveira Antia G. Pereira Catarina Lourenço-Lopes Cecilia Jimenez-Lopez Miguel Angel Prieto Jesus Simal-Gandara Tannins are polyphenolic compounds naturally found in vegetables. Their presence in nature has prompted their historical use in many different ways. The revision of their traditional utilization...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 608: Impact of Drying Method on the Evaluation of Fatty Acids and Their Derived Volatile Compounds in ‘Thompson Seedless’ Raisins Molecules doi: 10.3390/molecules25030608 Authors: Dong Wang Hafiz Umer Javed Ying Shi Safina Naz Sajid Ali Chang-Qing Duan Air- and sun-dried raisins from Thompson Seedless (TS) grapes were analyzed under GC/MS to evaluate fatty acids (FAs) and their derived volatile compounds, coming from unsaturated fatty acids oxidation....
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 611: Synthesis of 2,2,6-Trisubstituted 5-Methylidene-tetrahydropyran-4-ones with Anticancer Activity Molecules doi: 10.3390/molecules25030611 Authors: Bartosik Kędzia Drogosz-Stachowicz Janecka Krajewska Mirowski Janecki In our continuous search for new, relatively simple 2-alkylidene-1-oxoheterocycles as promising anticancer drug candidates, herein we report an efficient synthesis of 2,2,6-trisubstituted 5-methylidenetetrahydropyran-4-ones....
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 610: Effect of Membrane Surface Modification Using Chitosan Hydrochloride and Lactoferrin on the Properties of Astaxanthin-Loaded Liposomes Molecules doi: 10.3390/molecules25030610 Authors: Qiang Pang Ma Ma Liu Astaxanthin-loaded liposomes were prepared by a thin-film ultrasonic method, and the effects of the different membrane surface modifiers chitosan hydrochloride (CH) and lactoferrin (LF) on the physicochemical stability of the liposomes...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 609: AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism Molecules doi: 10.3390/molecules25030609 Authors: Khavinson Diomede Mironova Linkova Trofimova Trubiani Caputi Sinjari It was shown that AEDG peptide (Ala-Glu-Asp-Gly, Epitalon) regulates the function of the pineal gland, the retina, and the brain. AEDG peptide increases longevity in animals and decreases...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 607: Redox-Active Monolayers Self-Assembled on Gold Electrodes—Effect of Their Structures on Electrochemical Parameters and DNA Sensing Ability Molecules doi: 10.3390/molecules25030607 Authors: Malecka Menon Palla Kumar Daniels Dehaen Radecka Radecki The background: The monolayers self-assembled on the gold electrode incorporated transition metal complexes can act both as receptor (“host” molecules) immobilization...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 606: Transforming of Triptolide into Characteristic Metabolites by the Gut Microbiota Molecules doi: 10.3390/molecules25030606 Authors: Peng Ma Fu Han Pan Zhang Yu Wang The importance of the gut microbiota in drug metabolism, especially in that of nonabsorbable drugs, has become known. The aim of this study was to explore the metabolites of triptolide by the gut microbiota. With high-performance liquid chromatography coupled with...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 613: Phytochemical and Safety Evaluations of Volatile Terpenoids from Zingiber Cassumunar Roxb. On Mature Carp Peripheral Blood Mononuclear Cells and Embryonic Zebrafish Molecules doi: 10.3390/molecules25030613 Authors: Mektrirat Yano Okonogi Katip Pikulkaew Pharmaceutical products of essential oil from Zingiber cassumunar Roxb. are extensively being developed, while the research on their safety is seldom documented. The aim of the present study...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 599: Baicalein Alleviates Liver Oxidative Stress and Apoptosis Induced by High-Level Glucose through the Activation of the PERK/Nrf2 Signaling Pathway Molecules doi: 10.3390/molecules25030599 Authors: Dong Xing Sun Sun Xu Quan Baicalein, a widely-distributed natural flavonoid, exhibits antioxidative activity in mice with type-2 diabetes. However, the underlying mechanisms remain partially elucidated. In this study, we investigated the effect...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 604: Synergistic Antitumor Effects on Drug-Resistant Breast Cancer of Paclitaxel/Lapatinib Composite Nanocrystals Molecules doi: 10.3390/molecules25030604 Authors: Wang Lv Wang Du Guo Chen Zhao Liu Liu Drug resistance presents serious difficulties for cancer treatment. A combination of paclitaxel (PTX) and lapatinib (LAPA) shows potentials in multiple drug resistant cancers in the clinic, but it is almost impossible to deliver...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 601: Effect of Transitional Metals (Mn and Ni) Substitution in LiCoPO4 Olivines Molecules doi: 10.3390/molecules25030601 Authors: Palumbo Manzi Meggiolaro Vitucci Trequattrini Curcio Paolone Brutti Transition metal substitution is a key strategy to optimize the functional properties of advanced crystalline materials used as positive electrodes in secondary lithium batteries (LIBs). Here we investigate the structural alterations...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 603: The Use of Different Commercial Mineral Water Brands to Produce Oil-In-Water Nanoemulsions Molecules doi: 10.3390/molecules25030603 Authors: Rocha-Filho Monteiro Agostinho Oliveira Nanoemulsions are submicron-size colloidal systems that have the ability to encapsulate, protect, and deliver active ingredients. They have been used in the pharmaceutical, cosmetics, and food industries to improve the absorption of drugs by the skin or via the gastrointestinal...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 598: Xanthones, A Promising Anti-Inflammatory Scaffold: Structure, Activity, and Drug Likeness Analysis Molecules doi: 10.3390/molecules25030598 Authors: Zheling Feng Xiuqiang Lu Lishe Gan Qingwen Zhang Ligen Lin Inflammation is the body’s self-protective response to multiple stimulus, from external harmful substances to internal danger signals released after trauma or cell dysfunction. Many diseases are considered to be related to inflammation,...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 602: Nickel-Catalyzed Removal of Alkene Protecting Group of Phenols, Alcohols via Chain Walking Process Molecules doi: 10.3390/molecules25030602 Authors: Meng Niu Ning Wu Yi An efficient nickel-catalyzed removal of alkene protection group under mild condition with high functional group tolerance through chain walking process has been established. Not only phenolic ethers, but also alcoholic ethers can be tolerated with the retention of stereocenter...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 600: Alternative Structures of α-Synuclein Molecules doi: 10.3390/molecules25030600 Authors: Dułak Gadzała Banach Konieczny Roterman The object of our analysis is the structure of alpha-synuclein (ASyn), which, under in vivo conditions, associates with presynaptic vesicles. Misfolding of ASyn is known to be implicated in Parkinson’s disease. The availability of structural information for both the micelle-bound and amyloid form of ASyn...
Thu Jan 30, 2020 02:00
Molecules, Vol. 25, Pages 605: Aza- and Azo-Stilbenes: Bio-Isosteric Analogs of Resveratrol Molecules doi: 10.3390/molecules25030605 Authors: Lizard Latruffe Vervandier-Fasseur Several series of natural polyphenols are described for their biological and therapeutic potential. Natural stilbenoid polyphenols, such as trans-resveratrol, pterostilbene and piceatannol are well-known for their numerous biological activities. However, their moderate bio-availabilities, especially for...
Thu Jan 30, 2020 02:00
Nanomaterials, Vol. 10, Pages 250: High-Efficiency Metasurfaces with 2π Phase Control Based on Aperiodic Dielectric Nanoarrays Nanomaterials doi: 10.3390/nano10020250 Authors: Shang Tang Ye Li Li Wu Wu Chen Zhang Yang Zheng In this study, the high-efficiency phase control Si metasurfaces are investigated based on aperiodic nanoarrays unlike widely-used period structures, the aperiodicity of which providing additional freedom to improve metasurfaces’...
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Nanomaterials, Vol. 10, Pages 249: Bulk-Like SnO2-Fe2O3@Carbon Composite as a High-Performance Anode for Lithium Ion Batteries Nanomaterials doi: 10.3390/nano10020249 Authors: Jie Deng Yu Dai Zhe Xiao Shuang Song Hui Dai Luming Li Jing Li Boosted power handling and the reduced charging duration of Li ion cells critically rests with ionic/electronic mobility. Ion mobility in electrochemically relevant grains normally stands for an essential restriction of the velocity...
Thu Jan 30, 2020 02:00
Nanomaterials, Vol. 10, Pages 245: Performance of Graphene–CdS Hybrid Nanocomposite Thin Film for Applications in Cu(In,Ga)Se2 Solar Cell and H2 Production Nanomaterials doi: 10.3390/nano10020245 Authors: Alhammadi Minnam Reddy Gedi Park Sayed Shim Kim A graphene–cadmium sulfide (Gr–CdS) nanocomposite was prepared by a chemical solution method, and its material properties were characterized by several analysis techniques. The synthesized pure...
Thu Jan 30, 2020 02:00
Nanomaterials, Vol. 10, Pages 247: Binder-Free V2O5 Cathode for High Energy Density Rechargeable Aluminum-Ion Batteries Nanomaterials doi: 10.3390/nano10020247 Authors: Diem Fenk Bill Burghard Nowadays, research on electrochemical storage systems moves into the direction of post-lithium-ion batteries, such as aluminum-ion batteries, and the exploration of suitable materials for such batteries. Vanadium pentoxide (V2O5) is one of the most promising host materials for the...
Thu Jan 30, 2020 02:00
Nanomaterials, Vol. 10, Pages 246: Smoothing the Surface and Improving the Electrochemical Properties of NaxMnO2 by a Wet Chemical Method Nanomaterials doi: 10.3390/nano10020246 Authors: Zhao Lin Wu Xiao Xu NaxMnO2 (NMO) is treated by a wet chemical method in this paper. The treated NMO can form a copper oxide coating layer, and some of the coating layer can be peeled off, smoothing the surface of particles. Electrochemical measurement shows that treated NMO can maintain...
Thu Jan 30, 2020 02:00
Nanomaterials, Vol. 10, Pages 248: Systematic Design of Polypyrrole/Carbon Fiber Electrodes for Efficient Flexible Fiber-Type Solid-State Supercapacitors Nanomaterials doi: 10.3390/nano10020248 Authors: Sung Lin Fiber-type supercapacitors (FSC) have attracted much attention as efficient energy storage devices for soft electronics. This study proposes the synthesis of polypyrrole (PPy) on carbon fiber (CF) using electropolymerization as the energy storage electrode for FSC. Effects...
Thu Jan 30, 2020 02:00
Nutrients, Vol. 12, Pages 370: The Effects of Cholecalciferol Supplementation on Vitamin D Status Among a Diverse Population of Collegiate Basketball Athletes: A Quasi-Experimental Trial Nutrients doi: 10.3390/nu12020370 Authors: Nicole M. Sekel Sina Gallo Jennifer Fields Andrew R. Jagim Tammy Wagner Margaret T. Jones Vitamin D may play a role in performance and injury risk, yet the required supplementation dosage for collegiate athletes is unclear. The objective of this...
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Nutrients, Vol. 12, Pages 368: Effect of Oral Probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 on the Vaginal Microbiota, Cytokines and Chemokines in Pregnant Women Nutrients doi: 10.3390/nu12020368 Authors: Yang Reid Challis Gloor Asztalos Money Seney Bocking Spontaneous preterm birth is associated with vaginal microbial dysbiosis. As certain strains of lactobacilli help restore homeostasis in non-pregnant women, the goal was to determine...
Thu Jan 30, 2020 02:00
Nutrients, Vol. 12, Pages 369: Anti-Menopausal Effects of Cornus officinalis and Ribes fasciculatum Extract In Vitro and In Vivo Nutrients doi: 10.3390/nu12020369 Authors: Park Lim Yeo Yong Yang Jeong : Natural herbal medicines have been developed for the treatment and prevention of women’s menopausal symptoms. In this study, we investigated the anti-menopausal effects of Cornus officinalis (CO) and Ribes fasciculatum (RF) extracts in 3T3-L1 preadipocytes,...
Thu Jan 30, 2020 02:00
Nutrients, Vol. 12, Pages 365: The Effects of Different Quantities and Qualities of Protein Intake in People with Diabetes Mellitus Nutrients doi: 10.3390/nu12020365 Authors: Andreas F.H. Pfeiffer Eva Pedersen Ursula Schwab Ulf Risérus Anne-Marie Aas Matti Uusitupa Anastasia Thanopoulou Cyril Kendall John L. Sievenpiper Hana Kahleová Dario Rahélic Jordi Salas-Salvadó Stephanie Gebauer Kjeld Hermansen The recommended amount and quality of protein...
Thu Jan 30, 2020 02:00
Nutrients, Vol. 12, Pages 362: Dietary Knowledge and Myths Vary by Age and Years of Schooling in Pregnant Mexico City Residents Nutrients doi: 10.3390/nu12020362 Authors: Sámano Lara-Cervantes Martínez-Rojano Chico-Barba Sánchez-Jiménez Lokier Hernández-Trejo Grosso Heller Pregnancy is a stage in a woman’s life when she is more open to receiving health advice, especially related to diet. However, women are often caught between receiving scientifically...
Thu Jan 30, 2020 02:00
Nutrients, Vol. 12, Pages 367: Obesity Is Less Frequently Associated with Cognitive Impairment in Elderly Individuals: A Cross-Sectional Study in Yogyakarta, Indonesia Nutrients doi: 10.3390/nu12020367 Authors: Amelia Nur Vidyanti Muhammad Hardhantyo Bayu Satria Wiratama Astuti Prodjohardjono Chaur-Jong Hu Obesity is one of the factors associated with cognitive impairment. However, obesity may differently affect cognitive function in different age groups, and scarce data...
Thu Jan 30, 2020 02:00
Nutrients, Vol. 12, Pages 364: Effects of 1,25-dihydroxyvitamin D3 on the Inflammatory Responses of Stromal Vascular Cells and Adipocytes from Lean and Obese Mice Nutrients doi: 10.3390/nu12020364 Authors: Park Kim Yoo Seo Pae Han Vitamin D status has been implicated in obesity and adipose tissue inflammation. In the present study, we explored the effects of dietary vitamin D supplementation on adipose tissue inflammation and immune cell population, and the effects...
Thu Jan 30, 2020 02:00
Nutrients, Vol. 12, Pages 361: Food Intervention with Folate Reduces TNF-α and Interleukin Levels in Overweight and Obese Women with the MTHFR C677T Polymorphism: A Randomized Trial Nutrients doi: 10.3390/nu12020361 Authors: Lisboa Ribeiro Luna Lima Nascimento Monteiro Lima Fechine Oliveira Persuhn Veras Gonçalves Ferreira Lima Silva Diniz Almeida Moraes Junior Costa Methylenetetrahydrofolate reductase (MTHFR)...
Thu Jan 30, 2020 02:00
Nutrients, Vol. 12, Pages 363: Lactobacillus acidophilus DDS-1 and Bifidobacterium lactis UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial Nutrients doi: 10.3390/nu12020363 Authors: Martoni Srivastava Leyer This randomized, double-blind, placebo-controlled, multi-center study investigated the clinical efficacy of two probiotic strains on abdominal pain severity and symptomology in irritable bowel syndrome (IBS)....
Thu Jan 30, 2020 02:00
Nutrients, Vol. 12, Pages 366: Associations of Dietary Sodium, Potassium, and Sodium to Potassium Ratio with Blood Pressure— Regional Disparities in China Nutrients doi: 10.3390/nu12020366 Authors: Huang Wang Wang Wang Zhang Ding High dietary sodium and low potassium intake increase blood pressure and risk of hypertension, but whether the relationship between dietary sodium and potassium and risk of hypertension is different in North China and South China remains...
Thu Jan 30, 2020 02:00
Pathogens, Vol. 9, Pages 87: Novel Cytoplasmic Bacteriocin Compounds Derived from Staphylococcus epidermidis Selectively Kill Staphylococcus aureus, Including Methicillin-Resistant Staphylococcus aureus (MRSA) Pathogens doi: 10.3390/pathogens9020087 Authors: Jang Yang Kim Park Staphylococcus aureus (S. aureus) is one of the well-known agents causing atopic dermatitis (AD) in susceptible individuals, and Staphylococcus epidermidis (S. epidermidis) produces class I thermostable...
Thu Jan 30, 2020 02:00
Pharmaceuticals, Vol. 13, Pages 22: Radiolabelled Peptides for Positron Emission Tomography and Endoradiotherapy in Oncology Pharmaceuticals doi: 10.3390/ph13020022 Authors: Rangger Haubner This review deals with the development of peptide-based radiopharmaceuticals for the use with positron emission tomography and peptide receptor radiotherapy. It discusses the pros and cons of this class of radiopharmaceuticals as well as the different labelling strategies, and summarises approaches...
Thu Jan 30, 2020 02:00
Plants, Vol. 9, Pages 167: Crocus sativus L. Extract Containing Polyphenols Modulates Oxidative Stress and Inflammatory Response against Anti-Tuberculosis Drugs-Induced Liver Injury Plants doi: 10.3390/plants9020167 Authors: Adil Farooq Wali Jayachithra Ramakrishna Pillai Yusra Al Dhaheri Muneeb U. Rehman Ambreen Shoaib Omar Sarheed Salma Jabnoun Maryam Razmpoor Saiema Rasool Bilal Ahmad Paray Parvaiz Ahmad The purpose of this study is to analyze the polyphenolic...
Thu Jan 30, 2020 02:00
Religions, Vol. 11, Pages 66: Compassion, Self-Sacrifice, and Karma in Warfare: Buddhist Discourse on Warfare as an Ethical and Soteriological Instruction for Warriors Religions doi: 10.3390/rel11020066 Authors: Sugiki In premodern warrior societies, religions often provided the institutional basis for an ethics and soteriology for warriors, for whom fighting was a social role. This paper examines a Buddhist case in ancient India. I focus particularly on the discourse related to warfare...
Thu Jan 30, 2020 02:00
Risks, Vol. 8, Pages 11: General Conditions of Weak Convergence of Discrete-Time Multiplicative Scheme to Asset Price with Memory Risks doi: 10.3390/risks8010011 Authors: Yuliya Mishura Kostiantyn Ralchenko Sergiy Shklyar We present general conditions for the weak convergence of a discrete-time additive scheme to a stochastic process with memory in the space D [ 0 , T ] . Then we investigate the convergence of the related multiplicative scheme to a process that can be interpreted...
Thu Jan 30, 2020 02:00
Sci, Vol. 2, Pages 5: XRF Quick-Scan Mapping for Heavy Metal Pollutants in SuDS: A Methodological Approach Sci doi: 10.3390/sci2010005 Authors: Venvik Boogaard Sustainable urban drainage systems (SuDS) such as swales are designed to collect, store and infiltrate a large amount of surface runoff water during heavy rainfall. Stormwater is known to transport pollutants, such as particle-bound heavy metals, which are known to often accumulate in the topsoil. In this study, a portable...
Thu Jan 30, 2020 02:00
Societies, Vol. 10, Pages 14: Exploring the Role of ‘Shadowing’ as a Beneficial Preparatory Step for Sensitive Qualitative Research with Children and Young People with Serious Health Conditions Societies doi: 10.3390/soc10010014 Authors: Tyldesley-Marshall Greenfield Neilson Adamski Beardsmore English Peet This article aims to explore and record the role of shadowing in preparation for a qualitative study involving children and families with sensitive health...
Thu Jan 30, 2020 02:00
Toxins, Vol. 12, Pages 95: The Impacts of Asparagus Extract Fractions on Growth and Fumonisins Biosynthesis in Fusarium Proliferatum Toxins doi: 10.3390/toxins12020095 Authors: Witaszak Lalak-Kańczugowska Waśkiewicz Stępień Asparagus is a genus consisting of over two hundred species of perennial plants. Fusarium proliferatum is a major asparagus pathogen and it biosynthesizes a variety of mycotoxins, of which fumonisins B are prevalent. Our previous studies on F. proliferatum...
Thu Jan 30, 2020 02:00
Vaccines, Vol. 8, Pages 58: Differential Immune Transcriptome and Modulated Signalling Pathways in Rainbow Trout Infected with Viral Haemorrhagic Septicaemia Virus (VHSV) and Its Derivative Non-Virion (NV) Gene Deleted Vaccines doi: 10.3390/vaccines8010058 Authors: Chinchilla Encinas Coll Gomez-Casado Viral haemorrhagic septicaemia virus (VHSV) is one of the worst viral threats to fish farming. Non-virion (NV) gene-deleted VHSV (dNV-VHSV) has been postulated as an attenuated...
Thu Jan 30, 2020 02:00
Viruses, Vol. 12, Pages 161: Differential Features of Fusion Activation within the Paramyxoviridae Viruses doi: 10.3390/v12020161 Authors: Azarm Lee Paramyxovirus (PMV) entry requires the coordinated action of two envelope glycoproteins, the receptor binding protein (RBP) and fusion protein (F). The sequence of events that occurs during the PMV entry process is tightly regulated. This regulation ensures entry will only initiate when the virion is in the vicinity of a target cell...
Thu Jan 30, 2020 02:00
Water, Vol. 12, Pages 381: Impact Analysis of Univariate and Multivariate Bias Correction on Rice Irrigation Water Needs in Jiangxi Province, China Water doi: 10.3390/w12020381 Authors: Hanggoro Yuanshu Cudemus Zhihao Regional climate models (RCMs) provide an improved representation of climate information as compared to global climate models (GCMs). However, in climate-agricultural impact studies, accurate and interdependent local-scale climate variables are preferable,...
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Water, Vol. 12, Pages 379: Application of Stable Water Isotopes to Improve Conceptual Model of Alluvial Aquifer in the Varaždin Area Water doi: 10.3390/w12020379 Authors: Marković Karlović Perčec Tadić Larva To understand groundwater flow and geochemical processes within an aquifer, it is necessary to set up a conceptual model of the aquifer. To accomplish this, different methods are used, and one of them is an isotopic technique. The study area is located in the Varaždin...
Thu Jan 30, 2020 02:00
Water, Vol. 12, Pages 380: Rainwater Harvesting for Sustainable Agriculture in High Water-Poor Areas in the West Bank, Palestine Water doi: 10.3390/w12020380 Authors: Shadeed Judeh Riksen In most arid regions of the world, the increasing agricultural water supply–demand gap jeopardizes sustainable agricultural development and, as such, undermines local food security. In such situations, unconventional water resource practices such as agricultural rainwater harvesting...
Thu Jan 30, 2020 02:00
Water, Vol. 12, Pages 377: The Origin of Sand and Its Colour on the South-Eastern Coast of Spain: Implications for Erosion Management Water doi: 10.3390/w12020377 Authors: Asensio-Montesinos Pranzini Martínez-Martínez Cinelli Anfuso Corbí Sand colour can give important information about mineral composition and, consequently, sediment source areas and input systems. Beach appearance, which is mostly linked to sand colour, has a relevant economic function in tourist...
Thu Jan 30, 2020 02:00
Water, Vol. 12, Pages 376: Glacial Stream Ecology: Structural and Functional Assets Water doi: 10.3390/w12020376 Authors: Leopold Füreder Georg H. Niedrist High altitude glacier-fed streams are harsh environments inhabiting specialized invertebrate communities. Most research on biotic aspects in glacier-fed streams have focused on the simple relationship between presence/absence of species and prevailing environmental conditions, whereas functional strategies and potentials of glacial...
Thu Jan 30, 2020 02:00
Water, Vol. 12, Pages 378: Designing Human Rights for Duty Bearers: Making the Human Rights to Water and Sanitation Part of Everyday Practice at the Local Government Level Water doi: 10.3390/w12020378 Authors: Carrard Neumeyer Pati Siddique Choden Abraham Gosling Roaf Torreano Bruhn In most countries, local governments bear primary responsibility for ensuring everyone has access to water and sanitation services. For the human rights to water and sanitation...
Thu Jan 30, 2020 02:00
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