Cells, Vol. 8, Pages 789: A Ciliary View of the Immunological Synapse Cells doi: 10.3390/cells8080789 Authors: Cassioli Baldari The primary cilium has gone from being a vestigial organelle to a crucial signaling hub of growing interest given the association between a group of human disorders, collectively known as ciliopathies, and defects in its structure or function. In recent years many ciliogenesis proteins have been observed at extraciliary sites in cells and likely perform...
Mon Jul 29, 2019 03:00
Cells, Vol. 8, Pages 788: The Dynamic 3D Genome in Gametogenesis and Early Embryonic Development Cells doi: 10.3390/cells8080788 Authors: Li An Zhang During gametogenesis and early embryonic development, the chromatin architecture changes dramatically, and both the transcriptomic and epigenomic landscape are comprehensively reprogrammed. Understanding these processes is the holy grail in developmental biology and a key step towards evolution. The 3D conformation of chromatin...
Mon Jul 29, 2019 03:00
Cells, Vol. 8, Pages 790: NK Cell Induced T Cell Anergy Depends on GRAIL Expression Cells doi: 10.3390/cells8080790 Authors: Grazyna Galazka Malgorzata Domowicz Alicja Ewiak-Paszynska Anna Jurewicz NK cells (natural killer cells) being a part of the innate immune system have been shown to be involved in immunoregulation of autoimmune diseases. Previously we have shown that HINT1/Hsp70 treatment induced regulatory NK cells ameliorating experimental autoimmune encephalomyelitis...
Mon Jul 29, 2019 03:00
Cells, Vol. 8, Pages 787: An Omics Approach to Extracellular Vesicles from HIV-1 Infected Cells Cells doi: 10.3390/cells8080787 Authors: Robert A. Barclay Pooja Khatkar Gifty Mensah Catherine DeMarino Jeffery S. C. Chu Benjamin Lepene Weidong Zhou Patrick Gillevet Bahareh Torkzaban Kamel Khalili Lance Liotta Fatah Kashanchi Human Immunodeficiency Virus-1 (HIV-1) is the causative agent of Acquired Immunodeficiency Syndrome (AIDS), infecting nearly 37 million...
Mon Jul 29, 2019 03:00
Cells, Vol. 8, Pages 786: Naturally Occurring Nervonic Acid Ester Improves Myelin Synthesis by Human Oligodendrocytes Cells doi: 10.3390/cells8080786 Authors: Natalia Lewkowicz Paweł Piątek Magdalena Namiecińska Małgorzata Domowicz Radosław Bonikowski Janusz Szemraj Patrycja Przygodzka Mariusz Stasiołek Przemysław Lewkowicz The dysfunction of oligodendrocytes (OLs) is regarded as one of the major causes of inefficient remyelination in multiple sclerosis, resulting...
Mon Jul 29, 2019 03:00
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