Molecules, Vol. 24, Pages 2760: Catalytic Production of Levulinic Acid (LA) from Actual Biomass Molecules doi: 10.3390/molecules24152760 Authors: Michela Signoretto Somayeh Taghavi Elena Ghedini Federica Menegazzo Catalytic conversion of actual biomass to valuable chemicals is a crucial issue in green chemistry. This review discusses on the recent approach in the levulinic acid (LA) formation from three prominent generations of biomasses. Our paper highlights the impact of the...
Molecules, Vol. 24, Pages 2759: Magnetized Carbon Nanotube Based Lateral Flow Immunoassay for Visual Detection of Complement Factor B Molecules doi: 10.3390/molecules24152759 Authors: Yan Huang Tingting Wu Fang Wang Kun Li Lisheng Qian Xueji Zhang Guodong Liu The authors describe a magnetized carbon nanotube (MCNT) based lateral flow immunoassay (LFI) for visual detection of complement factor B (CFB) in blood. MCNT was prepared by decorating magnetic Fe3O4 nanoparticles...
Molecules, Vol. 24, Pages 2757: Novel Benzothiazole-based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer’s Disease Treatment Molecules doi: 10.3390/molecules24152757 Authors: Aitken Benek McKelvie Hughes Hroch Schmidt Major Vinklarova Kuca Smith Musilek Gunn-Moore : It has long been established that mitochondrial dysfunction in Alzheimer’s disease (AD) patients can trigger pathological changes in cell metabolism by altering...
Molecules, Vol. 24, Pages 2755: Removal of Reactive Dyes in Textile Effluents by Catalytic Ozonation Pursuing on-Site Effluent Recycling Molecules doi: 10.3390/molecules24152755 Authors: Hu Shang Chiu The textile wash-off process consumes substantial amounts of water, which generates large volumes of wastewater that pose potential pollution issues for the environment. In the present study, catalytic ozonation was applied to degrade residual dyes present in rinsing effluents...
Molecules, Vol. 24, Pages 2758: Magnetic Solid-Phase Extraction of Dichlorodiphenyltrichloroethane and Its Metabolites from Environmental Water Samples Using Ionic Liquid Modified Magnetic Multiwalled Carbon Nanotube/Zeolitic Imidazolate Framework-8 as Sorbent Molecules doi: 10.3390/molecules24152758 Authors: Huang Liu Liu Liu Xu Li Lv Liu Zhou Xu As persistent organic pollutants, dichlorodiphenyltrichloroethanes (DDTs) and their metabolites pose...
Molecules, Vol. 24, Pages 2756: Purification and Characterization of Ornithine Decarboxylase from Aspergillus terreus; Kinetics of Inhibition by Various Inhibitors Molecules doi: 10.3390/molecules24152756 Authors: Ashraf S.A. El-Sayed Nelly M. George Marwa A. Yassin Bothaina A. Alaidaroos Ahmed A. Bolbol Marwa S. Mohamed Amgad M. Rady Safa W. Aziz Rawia A. Zayed Mahmoud Z. Sitohy l-Ornithine decarboxylase (ODC) is the rate-limiting enzyme of de novo polyamine...
Molecules, Vol. 24, Pages 2753: Therapeutic Perspectives of Molecules from Urtica dioica Extracts for Cancer Treatment Molecules doi: 10.3390/molecules24152753 Authors: Sabrina Esposito Alessandro Bianco Rosita Russo Antimo Di Maro Carla Isernia Paolo Vincenzo Pedone A large range of chronic and degenerative diseases can be prevented through the use of food products and food bioactives. This study reports the health benefits and biological activities of the Urtica dioica...
Molecules, Vol. 24, Pages 2752: Revisiting the Allosteric Regulation of Sodium Cation on the Binding of Adenosine at the Human A2A Adenosine Receptor: Insights from Supervised Molecular Dynamics (SuMD) Simulations Molecules doi: 10.3390/molecules24152752 Authors: Maicol Bissaro Giovanni Bolcato Giuseppe Deganutti Mattia Sturlese Stefano Moro One of the most intriguing findings highlighted from G protein-coupled receptor (GPCR) crystallography is the presence, in many members...
Molecules, Vol. 24, Pages 2751: Ursolic Acid and Its Derivatives as Bioactive Agents Molecules doi: 10.3390/molecules24152751 Authors: Sithenkosi Mlala Adebola Omowunmi Oyedeji Mavuto Gondwe Opeoluwa Oyehan Oyedeji Non-communicable diseases (NCDs) such as cancer, diabetes, and chronic respiratory and cardiovascular diseases continue to be threatening and deadly to human kind. Resistance to and side effects of known drugs for treatment further increase the threat, while at the...
Molecules, Vol. 24, Pages 2754: Pharmacokinetic and Metabolism Studies of Monomethyl Auristatin F via Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry Molecules doi: 10.3390/molecules24152754 Authors: Park Lee Byeon Shin Choi Park Shin A simple liquid chromatography–quadrupole-time-of-flight–mass spectrometric assay (LC-TOF-MS/MS) has been developed for the evaluation of metabolism and pharmacokinetic (PK) characteristics...
Molecules, Vol. 24, Pages 2750: Nonlocal Buckling Analysis of Composite Curved Beams Reinforced with Functionally Graded Carbon Nanotubes Molecules doi: 10.3390/molecules24152750 Authors: Behrouz Karami Maziar Janghorban Davood Shahsavari Rossana Dimitri Francesco Tornabene This work deals with the size-dependent buckling response of functionally graded carbon nanotube-reinforced composite (FG-CNTRC) (FG-CNTRC) curved beams based on a higher-order shear deformation beam theory...
Molecules, Vol. 24, Pages 2748: Aristoteline, an Indole-Alkaloid, Induces Relaxation by Activating Potassium Channels and Blocking Calcium Channels in Isolated Rat Aorta Molecules doi: 10.3390/molecules24152748 Authors: Fernando Romero Javier Palacios Ignacio Jofré Cristian Paz Chukwuemeka R. Nwokocha Adrián Paredes Fredi Cifuentes Alkaloids derived from plants have shown great medicinal benefits, and are often reported for their use in cardiovascular disease management....
Molecules, Vol. 24, Pages 2747: Combined Ensemble Docking and Machine Learning in Identification of Therapeutic Agents with Potential Inhibitory Effect on Human CES1 Molecules doi: 10.3390/molecules24152747 Authors: Eliane Briand Ragnar Thomsen Kristian Linnet Henrik Berg Rasmussen Søren Brunak Olivier Taboureau The human carboxylesterase 1 (CES1), responsible for the biotransformation of many diverse therapeutic agents, may contribute to the occurrence of adverse drug...
Molecules, Vol. 24, Pages 2749: Genus Periploca (Apocynaceae): A Review of Its Classification, Phytochemistry, Biological Activities and Toxicology Molecules doi: 10.3390/molecules24152749 Authors: Mingjin Huang Shoumao Shen Chunli Luo Yan Ren The genus Periploca belongs to the family Apocynaceae, which is composed of approximately ten species of plants according to incomplete statistics. Most of these plants serve as folk medicines with a long history, especially Periploca...
Molecules, Vol. 24, Pages 2745: Highly Selective, Aptamer-Based, Ultrasensitive Nanogold Colorimetric Smartphone Readout for Detection of Cd(II) Molecules doi: 10.3390/molecules24152745 Authors: Lu Xu Jun Liang Yonghui Wang Shuyue Ren Jin Wu Huanying Zhou Zhixian Gao A highly selective and sensitive method for Cd(II) detection was developed based on aptamer and gold nanoparticles (AuNPs) combined with a colorimetric smartphone readout. The experimental conditions such...
Molecules, Vol. 24, Pages 2746: A New Benzopyranyl Cadenane Sesquiterpene and Other Antiplasmodial and Cytotoxic Metabolites from Cleistochlamys kirkii Molecules doi: 10.3390/molecules24152746 Authors: Stephen S. Nyandoro Gasper Maeda Joan J.E. Munissi Amra Gruhonjic Paul A. Fitzpatrick Sofia Lindblad Sandra Duffy Jerry Pelletier Fangfang Pan Rakesh Puttreddy Vicky M. Avery Máté Erdélyi Phytochemical investigations of ethanol root bark and stem bark extracts...
Molecules, Vol. 24, Pages 2744: Effect of Surfactant Concentrations on Physicochemical Properties and Functionality of Curcumin Nanoemulsions Under Conditions Relevant to Commercial Utilization Molecules doi: 10.3390/molecules24152744 Authors: Thanida Chuacharoen Sehanat Prasongsuk Cristina M. Sabliov Surfactants are used to stabilize nanoemulsions by protecting their physical stability and preventing deterioration of the entrapped bioactive during processing and storage. The effect...
Molecules, Vol. 24, Pages 2743: Rational Design of Artificial Metalloproteins and Metalloenzymes with Metal Clusters Molecules doi: 10.3390/molecules24152743 Authors: Ying-Wu Lin Metalloproteins and metalloenzymes play important roles in biological systems by using the limited metal ions, complexes, and clusters that are associated with the protein matrix. The design of artificial metalloproteins and metalloenzymes not only reveals the structure and function relationship of natural proteins,...
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