Imatinib-Associated Pneumocystis jirovecii Pneumonia

Imatinib, sold under the brand names Gleevec among others, is a medication used to treat cancer. Specifically, it is used for chronic myelogenous leukemia and acute lymphocytic leukemia that are ... Wikipedia

Molar mass: 493.603 g/mol

Formula: C₂₉H₃₁N₇O

Elimination half-life: 18 h (imatinib); 40 h (active metabolite)

ATC code: L01XE01 (WHO)

License data: EU EMA: by INN; US FDA: IMATINIB

Metabolism: liver (mainly CYP3A4-mediated)

PDB ligand: STI (PDBe, RCSB PDB)

Imatinib-Associated Pneumocystis jirovecii Pneumonia in a Patient With Chronic Myeloid Leukemia

Daw, Jad BA1; Thapa, Bicky MD2; Chahine, Johnny MD2; Lak, Hassan MD2; Perez, Oscar MD2; Nair, Raunak MD2; Alomari, Mohammad MD2; Haddad, Abdo MD3

American Journal of Therapeutics: July 03, 2019 - Volume Publish Ahead of Print - Issue - p

doi: 10.1097/MJT.0000000000000963

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