Antibiotics, Vol. 9, Pages 647: A Comparison of Colistin versus Colistin Plus Meropenem for the Treatment of Carbapenem-Resistant Acinetobacter baumannii in Critically Ill Patients: A Propensity Score-Matched Analysis Antibiotics doi: 10.3390/antibiotics9100647 Authors: Wasan Katip Suriyon Uitrakul Peninnah Oberdorfer Carbapenem-resistant Acinetobacter baumannii (CRAB), an important nosocomial pathogen, occurs particularly in the intensive care unit (ICU). Thus, the aim of this...
03:00
Antibiotics, Vol. 9, Pages 646: The Prevalence of Multidrug Resistance of Helicobacter pylori and Its Impact on Eradication in Korea from 2017 to 2019: A Single-Center Study Antibiotics doi: 10.3390/antibiotics9100646 Authors: Jae Yong Park Tae-Seop Shin Ji Hyun Kim Hong Jip Yoon Beom Jin Kim Jae Gyu Kim Antimicrobial resistance is one of the major factors determining the efficacy of Helicobacter pylori eradication therapy. This study aimed to estimate the recent prevalence...
Sun Sep 27, 2020 03:00
Antibiotics, Vol. 9, Pages 645: Effect of Antibiotic Susceptibility and CYP3A4/5 and CYP2C19 Genotype on the Outcome of Vonoprazan-Containing Helicobacter pylori Eradication Therapy Antibiotics doi: 10.3390/antibiotics9100645 Authors: Mitsushige Sugimoto Daiki Hira Masaki Murata Takashi Kawai Tomohiro Terada Background: Helicobacter pylori eradication containing the potassium-competitive acid blocker, vonoprazan, achieves a higher eradication rate than therapy with proton...
Sat Sep 26, 2020 03:00
Antibiotics, Vol. 9, Pages 644: Preliminary Attempt to Predict Risk of Invasive Pulmonary Aspergillosis in Patients with Influenza: Decision Trees May Help? Antibiotics doi: 10.3390/antibiotics9100644 Authors: Valeria Bellelli Guido Siccardi Livia Conte Luigi Celani Elena Congeduti Cristian Borrazzo Letizia Santinelli Giuseppe Pietro Innocenti Claudia Pinacchio Giancarlo Ceccarelli Mario Venditti Gabriella d’Ettorre Invasive pulmonary aspergillosis (IPA)...
Sat Sep 26, 2020 03:00
Antibiotics, Vol. 9, Pages 643: Antibiotic Consumption Patterns in European Countries May Be Associated with the Incidence of Major Carcinomas Antibiotics doi: 10.3390/antibiotics9100643 Authors: Gábor Ternák Károly Berényi András Sümegi Ágnes Szenczi Barbara Fodor Balázs Németh István Kiss The possible role of the altered intestinal microbiome in the development of malignancies has been raised recently in several publications. Among external factors, antibiotics are...
Fri Sep 25, 2020 03:00
Antibiotics, Vol. 9, Pages 642: Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications Antibiotics doi: 10.3390/antibiotics9100642 Authors: Aurora Silva Sofia A. Silva M. Carpena P. Garcia-Oliveira P. Gullón M. Fátima Barroso M.A. Prieto J. Simal-Gandara In the last few decades, attention on new natural antimicrobial compounds has arisen due to a change in consumer preferences and the increase in the number of resistant microorganisms....
Fri Sep 25, 2020 03:00
Antioxidants, Vol. 9, Pages 926: Are Fried Foods Unhealthy? The Dietary Peroxidized Fatty Acid, 13-HPODE, Induces Intestinal Inflammation In Vitro and In Vivo Antioxidants doi: 10.3390/antiox9100926 Authors: Esra’a Keewan Chandrakala Aluganti Narasimhulu Michael Rohr Simran Hamid Sampath Parthasarathy Inflammatory Bowel Disease (IBD) is a chronic inflammatory disorder characterized by progressive inflammation and the erosion of the gut mucosa. Although the exact cause of...
Sun Sep 27, 2020 03:00
Antioxidants, Vol. 9, Pages 925: Oxidative Stress Markers in Chronic Kidney Disease with Emphasis on Diabetic Nephropathy Antioxidants doi: 10.3390/antiox9100925 Authors: Nina Vodošek Hojs Sebastjan Bevc Robert Ekart Radovan Hojs Diabetes prevalence is increasing worldwide, especially through the increase of type 2 diabetes. Diabetic nephropathy occurs in up to 40% of diabetic patients and is the leading cause of end-stage renal disease. Various factors affect the development...
Sun Sep 27, 2020 03:00
Antioxidants, Vol. 9, Pages 924: Involvement of HO-1 and Autophagy in the Protective Effect of Magnolol in Hepatic Steatosis-Induced NLRP3 Inflammasome Activation In Vivo and In Vitro Antioxidants doi: 10.3390/antiox9100924 Authors: Ni-Chun Kuo Shieh-Yang Huang Chien-Yi Yang Hsin-Hsueh Shen Yen-Mei Lee Magnolol (MG) is the main active compound of Magnolia officinalis and exerts a wide range of biological activities. In this study, we investigated the effects of MG using tyloxapol...
Sun Sep 27, 2020 03:00
Antioxidants, Vol. 9, Pages 923: Role of the Encapsulation in Bioavailability of Phenolic Compounds Antioxidants doi: 10.3390/antiox9100923 Authors: Josipa Grgić Gordana Šelo Mirela Planinić Marina Tišma Ana Bucić-Kojić Plant-derived phenolic compounds have multiple positive health effects for humans attributed to their antioxidative, anti-inflammatory, and antitumor properties, etc. These effects strongly depend on their bioavailability in the organism. Bioaccessibility,...
Sat Sep 26, 2020 03:00
Antioxidants, Vol. 9, Pages 921: Nigella Sativa’s Anti-Inflammatory and Antioxidative Effects in Experimental Inflammation Antioxidants doi: 10.3390/antiox9100921 Authors: Raluca Maria Pop Octavia Sabin Șoimița Suciu Stefan Cristian Vesa Sonia Ancuța Socaci Veronica Sanda Chedea Ioana Corina Bocsan Anca Dana Buzoianu Nigella sativa (NS) has been used for centuries in various inflammatory conditions because of its anti-inflammatory and antioxidant activities. The...
Sat Sep 26, 2020 03:00
Antioxidants, Vol. 9, Pages 920: Protective Effects and Molecular Signaling of n-3 Fatty Acids on Oxidative Stress and Inflammation in Retinal Diseases Antioxidants doi: 10.3390/antiox9100920 Authors: Ayana Suzumura Ryo Terao Hiroki Kaneko Oxidative stress and inflammation play crucial roles in the development and progression of retinal diseases. Retinal damage by various etiologies can result in retinopathy of prematurity (ROP), diabetic retinopathy (DR), and age-related macular...
Sat Sep 26, 2020 03:00
Antioxidants, Vol. 9, Pages 922: Ectopic Expression of Production of Anthocyanin Pigment 1 (PAP1) Improves the Antioxidant and Anti-Melanogenic Properties of Ginseng (Panax ginseng C.A. Meyer) Hairy Roots Antioxidants doi: 10.3390/antiox9100922 Authors: Sora Jin Tae Kyung Hyun The development of genetically engineered cell cultures has been suggested as a potential approach for the production of target compounds from medicinal plants. In this study, we generated PAP1 (production of...
Sat Sep 26, 2020 03:00
Antioxidants, Vol. 9, Pages 919: Memory-Enhancing Effects of Origanum majorana Essential Oil in an Alzheimer’s Amyloid beta1-42 Rat Model: A Molecular and Behavioral Study Antioxidants doi: 10.3390/antiox9100919 Authors: Paula Alexandra Postu Dragos Lucian Gorgan Oana Cioanca Manuela Russ Stefan Mikkat Michael Otto Glocker Lucian Hritcu Origanum L. (Lamiaceae) is an important genus of medicinal and aromatic plants used in traditional medicine since ancient times as...
Sat Sep 26, 2020 03:00
Antioxidants, Vol. 9, Pages 918: •BMPO-OOH Spin-Adduct as a Model for Study of Decomposition of Organic Hydroperoxides and the Effects of Sulfide/Selenite Derivatives. An EPR Spin-Trapping Approach Antioxidants doi: 10.3390/antiox9100918 Authors: Anton Misak Vlasta Brezova Marian Grman Lenka Tomasova Miroslav Chovanec Karol Ondrias Lipid hydroperoxides play an important role in various pathophysiological processes. Therefore, a simple model for organic hydroperoxides could...
Sat Sep 26, 2020 03:00
Antioxidants, Vol. 9, Pages 917: Uterine Dysfunction in Diabetic Mice: The Role of Hydrogen Sulfide Antioxidants doi: 10.3390/antiox9100917 Authors: Emma Mitidieri Domenico Vanacore Carlotta Turnaturi Raffaella Sorrentino Roberta d’Emmanuele di Villa Bianca It is well-known that the physiological uterine peristalsis, related to several phases of reproductive functions, plays a pivotal role in fertility and female reproductive health. Here, we have addressed the role of hydrogen...
Sat Sep 26, 2020 03:00
Antioxidants, Vol. 9, Pages 916: An Update on the Role of Dietary Phytochemicals in Human Skin Cancer: New Insights into Molecular Mechanisms Antioxidants doi: 10.3390/antiox9100916 Authors: Salman Ul Islam Muhammad Bilal Ahmed Haseeb Ahsan Mazharul Islam Adeeb Shehzad Jong Kyung Sonn Young Sup Lee Human skin is continuously subjected to environmental stresses, as well as extrinsic and intrinsic noxious agents. Although skin adopts various molecular mechanisms to maintain...
Fri Sep 25, 2020 03:00
Antioxidants, Vol. 9, Pages 915: Sex and SP-A2 Dependent NAD(H) Redox Alterations in Mouse Alveolar Macrophages in Response to Ozone Exposure: Potential Implications for COVID-19 Antioxidants doi: 10.3390/antiox9100915 Authors: He N. Xu Zhenwu Lin Chintan K. Gandhi Shaili Amatya Yunhua Wang Lin Z. Li Joanna Floros Co-enzyme nicotinamide adenine dinucleotide (NAD(H)) redox plays a key role in macrophage function. Surfactant protein (SP-) A modulates the functions of...
Fri Sep 25, 2020 03:00
Antioxidants, Vol. 9, Pages 914: Glutathione Supplementation as an Adjunctive Therapy in COVID-19 Antioxidants doi: 10.3390/antiox9100914 Authors: Vika Guloyan Buzand Oganesian Nicole Baghdasaryan Christopher Yeh Manpreet Singh Frederick Guilford Yu-Sam Ting Vishwanath Venketaraman Morbidity and mortality of coronavirus disease 2019 (COVID-19) are due in large part to severe cytokine storm and hypercoagulable state brought on by dysregulated host-inflammatory immune...
Fri Sep 25, 2020 03:00
Atmosphere, Vol. 11, Pages 1038: Comparing Simulations of Umbrella-Cloud Growth and Ash Transport with Observations from Pinatubo, Kelud, and Calbuco Volcanoes Atmosphere doi: 10.3390/atmos11101038 Authors: Larry G. Mastin Alexa R. Van Eaton The largest explosive volcanic eruptions produce umbrella clouds that drive ash radially outward, enlarging the area that impacts aviation and ground-based communities. Models must consider the effects of umbrella spreading when forecasting hazards...
Sun Sep 27, 2020 03:00
Atmosphere, Vol. 11, Pages 1037: Measuring the Vertical Profiles of Aerosol Extinction in the Lower Troposphere by MAX-DOAS at a Rural Site in the North China Plain Atmosphere doi: 10.3390/atmos11101037 Authors: Cheng Jin Ma Xu Ran Ma Chen Guo Yang Wang Wagner Ground-based multi-axis differential optical absorption spectroscopy (MAX-DOAS) measurements were performed during the summer (13 June–20 August) of 2014 at a rural site in North...
Sun Sep 27, 2020 03:00
Atmosphere, Vol. 11, Pages 1036: Intercomparison Study of the Impact of Climate Change on Renewable Energy Indicators on the Mediterranean Islands Atmosphere doi: 10.3390/atmos11101036 Authors: Alba de la Vara Claudia Gutiérrez Juan Jesús González-Alemán Miguel Ángel Gaertner The enhanced vulnerability of insular regions to climate change has been recently recognized by the European Union, which highlights the importance of undertaking adaptation and mitigation strategies according...
Sun Sep 27, 2020 03:00
Atmosphere, Vol. 11, Pages 1035: Differences in the Evolution of Pyrocumulonimbus and Volcanic Stratospheric Plumes as Observed by CATS and CALIOP Space-Based Lidars Atmosphere doi: 10.3390/atmos11101035 Authors: Christian Yorks Das Recent fire seasons have featured volcanic-sized injections of smoke aerosols into the stratosphere where they persist for many months. Unfortunately, the aging and transport of these aerosols are not well understood. Using space-based lidar, the...
Sun Sep 27, 2020 03:00
Atmosphere, Vol. 11, Pages 1034: Gaseous Elemental Mercury Concentrations along the Northern Gulf of Mexico Using Passive Air Sampling, with a Comparison to Active Sampling Atmosphere doi: 10.3390/atmos11101034 Authors: Byunggwon Jeon James V. Cizdziel J. Stephen Brewer Winston T. Luke Mark D. Cohen Xinrong Ren Paul Kelley Mercury is a toxic element that is dispersed globally through the atmosphere. Accurately measuring airborne mercury concentrations aids understanding...
Sat Sep 26, 2020 03:00
Atmosphere, Vol. 11, Pages 1033: Regional Characteristics of Long-Term Variability of Summer Precipitation in the Poyang Lake Basin and Possible Links with Large-Scale Circulations Atmosphere doi: 10.3390/atmos11101033 Authors: Hua Zhu Handan He Hongxiang Fan Ligang Xu Jiahu Jiang Mingliang Jiang Yanxue Xu Understanding the spatiotemporal regime of summer precipitation at local scales plays a key role in regional prevention and mitigation of floods disasters and water...
Fri Sep 25, 2020 03:00
Atmosphere, Vol. 11, Pages 1032: Mobile Aerosol Raman Polarizing Lidar LOSA-A2 for Atmospheric Sounding Atmosphere doi: 10.3390/atmos11101032 Authors: Sergei Nasonov Yurii Balin Marina Klemasheva Grigorii Kokhanenko Mikhail Novoselov Iogannes Penner Svetlana Samoilova Tamara Khodzher The mobile aerosol Raman polarizing lidar LOSA-A2 designed at V.E. Zuev Institute of Atmospheric Optics SB RAS is presented. Its main technical specifications are given. The lidar carries...
Fri Sep 25, 2020 03:00
Atmosphere, Vol. 11, Pages 1031: Origins and Spatial Distribution of Non-Pure Sulfate Particles (NSPs) in the Stratosphere Detected by the Balloon-Borne Light Optical Aerosols Counter (LOAC) Atmosphere doi: 10.3390/atmos11101031 Authors: Jean-Baptiste Renard Gwenaël Berthet Anny-Chantal Levasseur-Regourd Sergey Beresnev Alain Miffre Patrick Rairoux Damien Vignelles Fabrice Jégou While water and sulfuric acid droplets are the main component of stratospheric aerosols,...
Fri Sep 25, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 148: Prevalence of Worry-Induced Sleep Disturbance and Associated Factors among a National Sample of In-School Adolescents in Lebanon Behavioral Sciences doi: 10.3390/bs10100148 Authors: Supa Pengpid Karl Peltzer Persistent worry can cause significant distress among adolescents. The goal of this study was to estimate the prevalence and correlates of worry-induced sleep disturbance (WISD) among adolescent school children in Lebanon. Cross-sectional,...
Sun Sep 27, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 147: Perceptions and Emotional State of Mothers of Children with and without Microcephaly after the Zika Virus Epidemic in Rural Caribbean Colombia Behavioral Sciences doi: 10.3390/bs10100147 Authors: Kelly Romero-Acosta Elena Marbán-Castro Katy Arroyo Germán Arrieta Salim Mattar Zika virus (ZIKV) infection during pregnancy can cause neurological manifestations such as microcephaly. The aim of this study was to explore perceptions of ZIKV...
Fri Sep 25, 2020 03:00
Bioengineering, Vol. 7, Pages 117: Impact of Coping Veneering Techniques on the Survival of Implant-Supported Zirconia-Based-Crowns Cemented to Hybrid-Abutments: An-In-Vitro Study Bioengineering doi: 10.3390/bioengineering7040117 Authors: Shareen Hayel Elshiyab Noor Nawafleh Usman Khan Andreas Öchsner Roy George The objective of this study is to investigate the influence of veneering technique (hand-layering vs. milling) on the fracture resistance of bi-layer implant-supported...
Fri Sep 25, 2020 03:00
Biology, Vol. 9, Pages 313: Ganoderma Lucidum from Red Mushroom Attenuates Formaldehyde-Induced Liver Damage in Experimental Male Rat Model Biology doi: 10.3390/biology9100313 Authors: Babatunde Oluwafemi Adetuyi Tolulope Olamide Okeowo Oluwatosin Adefunke Adetuyi Oluwaseun Abraham Adebisi Olubanke Olujoke Ogunlana Oyeyemi Janet Oretade Najat Marraiki Amany Magdy Beshbishy Nermeen N. Welson Gaber El-Saber Batiha The majority of liver-related illnesses are caused...
Sun Sep 27, 2020 03:00
Biomedicines, Vol. 8, Pages 382: Therapeutic Anticancer Uses of the Active Principles of “Rhopalurus junceus” Venom Biomedicines doi: 10.3390/biomedicines8100382 Authors: Mario Dioguardi Giorgia Apollonia Caloro Luigi Laino Mario Alovisi Diego Sovereto Vito Crincoli Riccardo Aiuto Antonio Dioguardi Alfredo De Lillo Giuseppe Troiano Lorenzo Lo Muzio The Rhopalurus junceus is a scorpion belonging to the Buthidae family that finds its habitat in Cuba. This...
Sun Sep 27, 2020 03:00
Biomedicines, Vol. 8, Pages 381: Macrophage Stimulated by Low Ambient Temperature Hasten Tumor Growth via Glutamine Production Biomedicines doi: 10.3390/biomedicines8100381 Authors: Eun-Ji Lee Tae-Wook Chung Keuk-Jun Kim Boram Bae Bo-Sung Kim Suhkmann Kim Dongryeol Ryu Sung-Jin Bae Ki-Tae Ha Ambient temperature can regulate the immune response and affect tumor growth. Although thermoneutral caging reduces tumor growth via immune activation, little attention has...
Sat Sep 26, 2020 03:00
Biomedicines, Vol. 8, Pages 380: Lupeol, a Plant-Derived Flavonoid, Protects Mice Brains against Aβ-Induced Oxidative Stress and Neurodegeneration Biomedicines doi: 10.3390/biomedicines8100380 Authors: Riaz Ahmad Amjad Khan Hyeon Jin Lee Inayat Ur Rehman Ibrahim Khan Sayed Ibrar Alam Myeong Ok Kim Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that represents 60–70% of all dementia cases. AD is characterized by the formation...
Sat Sep 26, 2020 03:00
Biomedicines, Vol. 8, Pages 379: Vav1 Down-Modulates Akt2 Expression in Cells from Pancreatic Ductal Adenocarcinoma: Nuclear Vav1 as a Potential Regulator of Akt Related Malignancy in Pancreatic Cancer Biomedicines doi: 10.3390/biomedicines8100379 Authors: Silvia Grassilli Federica Brugnoli Rossano Lattanzio Simonetta Buglioni Valeria Bertagnolo Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive tumor malignancy worldwide, mainly due to uncontrolled metastasis....
Sat Sep 26, 2020 03:00
Biomedicines, Vol. 8, Pages 378: Non-Adherence to Statin Treatment in Older Patients with Peripheral Arterial Disease Depending on Persistence Status Biomedicines doi: 10.3390/biomedicines8100378 Authors: Martin Wawruch Gejza Wimmer Jan Murin Martina Paduchova Miriam Petrova Tomas Tesar Petra Matalova Beata Havelkova Michal Trnka Emma Aarnio The effectiveness of statins in secondary prevention of peripheral arterial disease (PAD) largely depends on patients’...
Fri Sep 25, 2020 03:00
Biomedicines, Vol. 8, Pages 377: An Examination of the Neutralization of In Vitro Toxicity of Chinese Cobra (Naja atra) Venom by Different Antivenoms Biomedicines doi: 10.3390/biomedicines8100377 Authors: Qing Liang Tam Minh Huynh Nicki Konstantakopoulos Geoffrey K. Isbister Wayne C. Hodgson The Chinese Cobra (Naja atra) is an elapid snake of major medical importance in southern China. We describe the in vitro neurotoxic, myotoxic, and cytotoxic effects of N. atra venom,...
Fri Sep 25, 2020 03:00
Biomolecules, Vol. 10, Pages 1374: Broad-Spectrum Preclinical Antitumor Activity of Chrysin: Current Trends and Future Perspectives Biomolecules doi: 10.3390/biom10101374 Authors: Moghadam Ang Asnaf Zabolian Saleki Yavari Esmaeili Zarrabi Ashrafizadeh Kumar Pharmacological profile of phytochemicals has attracted much attention to their use in disease therapy. Since cancer is a major problem for public health with high mortality and morbidity worldwide,...
Sun Sep 27, 2020 03:00
Biomolecules, Vol. 10, Pages 1373: Clinical Translational Potential in Skin Wound Regeneration for Adipose-Derived, Blood-Derived, and Cellulose Materials: Cells, Exosomes, and Hydrogels Biomolecules doi: 10.3390/biom10101373 Authors: Frazier Alarcon Wu Mohiuddin Motherwell Carlsson Christy Edwards Mackin Prevost Gloster Zhang Wang Hayes Gimble Acute and chronic skin wounds due to burns, pressure injuries, and trauma represent...
Sun Sep 27, 2020 03:00
Biomolecules, Vol. 10, Pages 1372: Aedes albopictus D7 Salivary Protein Prevents Host Hemostasis and Inflammation Biomolecules doi: 10.3390/biom10101372 Authors: Ines Martin-Martin Leticia Barion Smith Andrezza Campos Chagas Anderson Sá-Nunes Gaurav Shrivastava Paola Carolina Valenzuela-Leon Eric Calvo Mosquitoes inject saliva into the host skin to facilitate blood meal acquisition through active compounds that prevent hemostasis. D7 proteins are among the most abundant...
Sun Sep 27, 2020 03:00
Biomolecules, Vol. 10, Pages 1371: Sphaerostilbellins, New Antimicrobial Aminolipopeptide Peptaibiotics from Sphaerostilbella toxica Biomolecules doi: 10.3390/biom10101371 Authors: Bruno Perlatti Connie B. Nichols J. Andrew Alspaugh James B. Gloer Gerald F. Bills Sphaerostilbella toxica is a mycoparasitic fungus that can be found parasitizing wood-decay basidiomycetes in the southern USA. Organic solvent extracts of fermented strains of S. toxica exhibited potent antimicrobial...
Sat Sep 26, 2020 03:00
Biomolecules, Vol. 10, Pages 1370: Take Advantage of Glutamine Anaplerosis, the Kernel of the Metabolic Rewiring in Malignant Gliomas Biomolecules doi: 10.3390/biom10101370 Authors: Filipa Martins Luís G. Gonçalves Marta Pojo Jacinta Serpa Glutamine is a non-essential amino acid that plays a key role in the metabolism of proliferating cells including neoplastic cells. In the central nervous system (CNS), glutamine metabolism is particularly relevant, because the glutamine-glutamate...
Sat Sep 26, 2020 03:00
Biomolecules, Vol. 10, Pages 1369: Reducing SO2 Doses in Red Wines by Using Grape Stem Extracts as Antioxidants Biomolecules doi: 10.3390/biom10101369 Authors: Irene Esparza Blanca Martínez-Inda María José Cimminelli Maria Carmen Jimeno-Mendoza José Antonio Moler Nerea Jiménez-Moreno Carmen Ancín-Azpilicueta SO2 is a very important wine preservative. However, there are several drawbacks associated with the use of SO2 in wine. The aim of this work is to evaluate the...
Fri Sep 25, 2020 03:00
Biomolecules, Vol. 10, Pages 1367: Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation Biomolecules doi: 10.3390/biom10101367 Authors: Nikita Fernandes Luke Nero Shawn M. Lyons Pavel Ivanov Telsa M. Mittelmeier Timothy A. Bolger J. Ross Buchan Stress granules (SGs) are hypothesized to facilitate TAR DNA-binding protein 43 (TDP-43) cytoplasmic mislocalization and aggregation, which may underly amyotrophic lateral sclerosis pathology....
Fri Sep 25, 2020 03:00
Biomolecules, Vol. 10, Pages 1368: Effects of Curcumin in a Mouse Model of Very High Fat Diet-Induced Obesity Biomolecules doi: 10.3390/biom10101368 Authors: Iurii Koboziev Shane Scoggin Xiaoxia Gong Parvin Mirzaei Masoud Zabet-Moghaddam Mohammad Yosofvand Hanna Moussa Yava Jones-Hall Naima Moustaid-Moussa Worldwide rates of Western-diet-induced obesity epidemics are growing dramatically. Being linked with numerous comorbidities and complications, including cardiovascular...
Fri Sep 25, 2020 03:00
Biomolecules, Vol. 10, Pages 1366: Human Serum Albumin Binds Native Insulin and Aggregable Insulin Fragments and Inhibits Their Aggregation Biomolecules doi: 10.3390/biom10101366 Authors: Joanna Wasko Marian Wolszczak Zbigniew J. Kaminski Malgorzata Steblecka Beata Kolesinska The purpose of this study was to investigate whether Human Serum Albumin (HSA) can bind native human insulin and its A13–A19 and B12–B17 fragments, which are responsible for the aggregation...
Fri Sep 25, 2020 03:00
Biomolecules, Vol. 10, Pages 1365: High NRF2 Levels Correlate with Poor Prognosis in Colorectal Cancer Patients and with Sensitivity to the Kinase Inhibitor AT9283 In Vitro Biomolecules doi: 10.3390/biom10101365 Authors: Laura Torrente Gunjit Maan Asma Oumkaltoum Rezig Jean Quinn Angus Jackson Andrea Grilli Laura Casares Ying Zhang Evgeny Kulesskiy Jani Saarela Silvio Bicciato Joanne Edwards Albena T. Dinkova-Kostova Laureano de la Vega Aberrant...
Fri Sep 25, 2020 03:00
Biosensors, Vol. 10, Pages 136: Dopamine and Striatal Neuron Firing Respond to Frequency-Dependent DBS Detected by Microelectrode Arrays in the Rat Model of Parkinson’s Disease Biosensors doi: 10.3390/bios10100136 Authors: Guihua Xiao Yilin Song Yu Zhang Yu Xing Shengwei Xu Mixia Wang Junbo Wang Deyong Chen Jian Chen Xinxia Cai (1) Background: Deep brain stimulation (DBS) is considered as an efficient treatment method for alleviating motor symptoms in Parkinson’s...
03:00
Biosensors, Vol. 10, Pages 135: Nanofluidic Immobilization and Growth Detection of Escherichia coli in a Chip for Antibiotic Susceptibility Testing Biosensors doi: 10.3390/bios10100135 Authors: Jan F. Busche Svenja Möller Ann-Kathrin Klein Matthias Stehr Foelke Purr Margherita Bassu Thomas P. Burg Andreas Dietzel Infections with antimicrobial resistant bacteria are a rising threat for global healthcare as more and more antibiotics lose their effectiveness against...
Fri Sep 25, 2020 03:00
Brain Sciences, Vol. 10, Pages 683: O-Arm Navigated Frameless and Fiducial-Less Deep Brain Stimulation Brain Sciences doi: 10.3390/brainsci10100683 Authors: Krahulík Nevrlý Otruba Bardoň Hrabálek Pohlodek Kaňovský Valošek : Object: Deep brain stimulation (DBS) is a very useful procedure for the treatment of idiopathic Parkinson’s disease (PD), essential tremor, and dystonia. The authors evaluated the accuracy of the new method used in their center...
Sun Sep 27, 2020 03:00
Brain Sciences, Vol. 10, Pages 680: Participatory Art Activities Increase Salivary Oxytocin Secretion of ASD Children Brain Sciences doi: 10.3390/brainsci10100680 Authors: Sanae Tanaka Aiko Komagome Aya Iguchi-Sherry Akiko Nagasaka Teruko Yuhi Haruhiro Higashida Maki Rooksby Mitsuru Kikuchi Oko Arai Kana Minami Takahiro Tsuji Chiharu Tsuji Autism spectrum disorder (ASD) occurs in 1 in 160 children worldwide. Individuals with ASD tend to be unique in the...
Sun Sep 27, 2020 03:00
Brain Sciences, Vol. 10, Pages 681: Physiological Profile Assessment of Posture in Children and Adolescents with Autism Spectrum Disorder and Typically Developing Peers Brain Sciences doi: 10.3390/brainsci10100681 Authors: Cecilia Perin Giulio Valagussa Miryam Mazzucchelli Valentina Gariboldi Cesare Giuseppe Cerri Roberto Meroni Enzo Grossi Cesare Maria Cornaggia Jasmine Menant Daniele Piscitelli A sound postural system requires sensorimotor integration. Evidence...
Sun Sep 27, 2020 03:00
Brain Sciences, Vol. 10, Pages 682: Salivary Cortisol Levels Are Associated with Craving and Cognitive Performance in Cocaine-Abstinent Subjects: A Pilot Study Brain Sciences doi: 10.3390/brainsci10100682 Authors: Patricia Sampedro-Piquero Selene Vicario Aroha Pérez-Rivas César Venero Shishir Baliyan Luis Javier Santín Cortisol is a glucocorticoid hormone secreted by the adrenal cortex upon the activation of the hypothalamic-pituitary-adrenal (HPA) axis. Assessment of...
Sun Sep 27, 2020 03:00
Brain Sciences, Vol. 10, Pages 678: The 12-Item Self-Rating Questionnaire for Depressive Mixed State (DMX-12) for Screening of Mixed Depression and Mixed Features Brain Sciences doi: 10.3390/brainsci10100678 Authors: Hotaka Shinzato Yu Zamami Tsuyoshi Kondo For simultaneous screening of mixed features (MF) by DSM-5 and mixed depression (MD) by Benazzi, useful symptoms were extracted from our 12-item dimensional scale for depressive mixed state (DMX-12). Subjects were 190 consecutive...
Sun Sep 27, 2020 03:00
Brain Sciences, Vol. 10, Pages 679: IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood–Brain Barrier Brain Sciences doi: 10.3390/brainsci10100679 Authors: Daisuke Furutama Shinji Matsuda Yosuke Yamawaki Saki Hatano Ai Okanobu Takumi Memida Hiroshi Oue Tsuyoshi Fujita Kazuhisa Ouhara Mikihito Kajiya Noriyoshi Mizuno Takashi Kanematsu Kazuhiro Tsuga Hidemi Kurihara Background: Periodontal disease (PD) is a risk...
Sun Sep 27, 2020 03:00
Brain Sciences, Vol. 10, Pages 677: Statistical Permutation Test Reveals Progressive and Region-Specific Iron Accumulation in the Thalami of Children with Aspartylglucosaminuria Brain Sciences doi: 10.3390/brainsci10100677 Authors: Viljami Sairanen Anna Tokola Ritva Tikkanen Minna Laine Taina Autti Aspartylglucosaminuria (AGU) is a rare lysosomal storage disorder causing developmental delay, intellectual disability, and eventual death. A distinct feature in AGU is iron accumulation...
Sun Sep 27, 2020 03:00
Brain Sciences, Vol. 10, Pages 676: Effects of Psychoactive Massage in Outpatients with Depressive Disorders: A Randomized Controlled Mixed-Methods Study Brain Sciences doi: 10.3390/brainsci10100676 Authors: Michaela Maria Arnold Bruno Müller-Oerlinghausen Norbert Hemrich Dominikus Bönsch The clinical picture of depressive disorders is characterized by a plethora of somatic symptoms, psychomotor retardation, and, particularly, anhedonia. The number of patients with residual...
Sat Sep 26, 2020 03:00
Brain Sciences, Vol. 10, Pages 674: Brain Response Induced with Paired Associative Stimulation Is Related to Repetition Suppression of Motor Evoked Potential Brain Sciences doi: 10.3390/brainsci10100674 Authors: Shohreh Kariminezhad Jari Karhu Laura Säisänen Jusa Reijonen Mervi Könönen Petro Julkunen Repetition suppression (RS), i.e., the reduction of neuronal activity upon repetition of an external stimulus, can be demonstrated in the motor system using transcranial magnetic...
Sat Sep 26, 2020 03:00
Brain Sciences, Vol. 10, Pages 675: Recent Advances on the Role of GSK3β in the Pathogenesis of Amyotrophic Lateral Sclerosis Brain Sciences doi: 10.3390/brainsci10100675 Authors: Hyun-Jun Choi Sun Joo Cha Jang-Won Lee Hyung-Jun Kim Kiyoung Kim Amyotrophic lateral sclerosis (ALS) is a common neurodegenerative disease characterized by progressive motor neuron degeneration. Although several studies on genes involved in ALS have substantially expanded and improved our understanding...
Sat Sep 26, 2020 03:00
Brain Sciences, Vol. 10, Pages 672: An Emotion Assessment of Stroke Patients by Using Bispectrum Features of EEG Signals Brain Sciences doi: 10.3390/brainsci10100672 Authors: Choong Wen Yean Wan Khairunizam Wan Wan Ahmad Wan Azani Mustafa Murugappan Murugappan Yuvaraj Rajamanickam Abdul Hamid Adom Mohammad Iqbal Omar Bong Siao Zheng Ahmad Kadri Junoh Zuradzman Mohamad Razlan Shahriman Abu Bakar Emotion assessment in stroke patients gives meaningful information...
Fri Sep 25, 2020 03:00
Brain Sciences, Vol. 10, Pages 673: Emotional Dysregulation Mechanisms in Psychosomatic Chronic Diseases Revealed by the Instability Coefficient Brain Sciences doi: 10.3390/brainsci10100673 Authors: Cristina Ciuluvica (Neagu) Paolo Amerio Ioan Valeriu Grossu In the present work, we analyzed some emotional mechanisms (emotion dysregulation—ED, negative affect—NA, and emotional vulnerability) involved in chronic diseases by means of an interdisciplinary approach....
Fri Sep 25, 2020 03:00
Brain Sciences, Vol. 10, Pages 671: Cognitive Training Deep Dive: The Impact of Child, Training Behavior and Environmental Factors within a Controlled Trial of Cogmed for Fragile X Syndrome Brain Sciences doi: 10.3390/brainsci10100671 Authors: Haleigh Scott Danielle J. Harvey Yueju Li Yingratana A. McLennan Cindy K. Johnston Ryan Shickman Joseph Piven Julie B. Schweitzer David Hessl Children with fragile X syndrome (FXS) exhibit deficits in a variety of cognitive...
Fri Sep 25, 2020 03:00
Brain Sciences, Vol. 10, Pages 670: Mental Health and Family Functioning in Patients and Their Family Members after Traumatic Brain Injury: A Cross-Sectional Study Brain Sciences doi: 10.3390/brainsci10100670 Authors: Mari S. Rasmussen Juan Carlos Arango-Lasprilla Nada Andelic Tonje H. Nordenmark Helene L. Soberg Traumatic brain injury (TBI) affects the family as a whole. This study aimed to describe and compare mental health and family functioning in TBI patients and their...
Fri Sep 25, 2020 03:00
Brain Sciences, Vol. 10, Pages 669: Independent Components of EEG Activity Correlating with Emotional State Brain Sciences doi: 10.3390/brainsci10100669 Authors: Yasuhisa Maruyama Yousuke Ogata Laura A. Martínez-Tejada Yasuharu Koike Natsue Yoshimura Among brain-computer interface studies, electroencephalography (EEG)-based emotion recognition is receiving attention and some studies have performed regression analyses to recognize small-scale emotional changes; however, effective...
Fri Sep 25, 2020 03:00
Brain Sciences, Vol. 10, Pages 667: Effect of Age in Auditory Go/No-Go Tasks: A Magnetoencephalographic Study Brain Sciences doi: 10.3390/brainsci10100667 Authors: Mei-Yin Lin Chia-Hsiung Cheng Response inhibition is frequently examined using visual go/no-go tasks. Recently, the auditory go/no-go paradigm has been also applied to several clinical and aging populations. However, age-related changes in the neural underpinnings of auditory go/no-go tasks are yet to be elucidated. We...
Fri Sep 25, 2020 03:00
Brain Sciences, Vol. 10, Pages 668: Transcutaneous Vagus Nerve Stimulation Modulates EEG Microstates and Delta Activity in Healthy Subjects Brain Sciences doi: 10.3390/brainsci10100668 Authors: Lorenzo Ricci Pierpaolo Croce Jacopo Lanzone Marilisa Boscarino Filippo Zappasodi Mario Tombini Vincenzo Di Lazzaro Giovanni Assenza Transcutaneous vagus nerve stimulation (tVNS) is an alternative non-invasive method for the electrical stimulation of the vagus nerve with the...
Fri Sep 25, 2020 03:00
Cancers, Vol. 12, Pages 2774: Cannabidiol and Oxygen-Ozone Combination Induce Cytotoxicity in Human Pancreatic Ductal Adenocarcinoma Cell Lines Cancers doi: 10.3390/cancers12102774 Authors: Luongo Marinelli Zeppa Aguzzi Morelli Amantini Frassineti Costanzo Fanelli Santoni Nabissi : Pancreatic cancer (PC) is related to lifestyle risks, chronic inflammation, and germline mutations in BRCA1/2, ATM, MLH1, TP53, or CDKN2A. Surgical resection and adjuvant...
Sun Sep 27, 2020 03:00
Cancers, Vol. 12, Pages 2772: Integrated Multiparametric Radiomics and Informatics System for Characterizing Breast Tumor Characteristics with the OncotypeDX Gene Assay Cancers doi: 10.3390/cancers12102772 Authors: Michael A. Jacobs Christopher B. Umbricht Vishwa S. Parekh Riham H. El Khouli Leslie Cope Katarzyna J. Macura Susan Harvey Antonio C. Wolff Optimal use of multiparametric magnetic resonance imaging (mpMRI) can identify key MRI parameters and provide unique...
Sun Sep 27, 2020 03:00
Cancers, Vol. 12, Pages 2773: tRNA-Derived Small RNAs: Novel Epigenetic Regulators Cancers doi: 10.3390/cancers12102773 Authors: Joonhyeong Park Se Hee Ahn Myung Geun Shin Hak Kyun Kim Suhwan Chang An epigenetic change is a heritable genetic alteration that does not involve any nucleotide changes. While the methylation of specific DNA regions such as CpG islands or histone modifications, including acetylation or methylation, have been investigated in detail, the role of small...
Sun Sep 27, 2020 03:00
Cancers, Vol. 12, Pages 2769: Identification of Genes Whose Expression Overlaps Age Boundaries and Correlates with Risk Groups in Paediatric and Adult Acute Myeloid Leukaemia Cancers doi: 10.3390/cancers12102769 Authors: Lindsay Davis Ken I. Mills Kim H. Orchard Barbara-Ann Guinn Few studies have compared gene expression in paediatric and adult acute myeloid leukaemia (AML). In this study, we have analysed mRNA-sequencing data from two publicly accessible databases: (1) National...
Sun Sep 27, 2020 03:00
Cancers, Vol. 12, Pages 2771: Non-Invasive Early Detection of Oral Cancers Using Fluorescence Visualization with Optical Instruments Cancers doi: 10.3390/cancers12102771 Authors: Takamichi Morikawa Takahiko Shibahara Takeshi Nomura Akira Katakura Masayuki Takano Background: Oral cancer screening is important for early detection and early treatment, which help improve survival rates. Biopsy is the gold standard for a definitive diagnosis but is invasive and painful, while...
Sun Sep 27, 2020 03:00
Cancers, Vol. 12, Pages 2770: Cancer Predisposition Genes in Cancer-Free Families Cancers doi: 10.3390/cancers12102770 Authors: Guoqiao Zheng Calogerina Catalano Obul Reddy Bandapalli Nagarajan Paramasivam Subhayan Chattopadhyay Matthias Schlesner Rolf Sijmons Akseli Hemminki Dagmara Dymerska Jan Lubinski Kari Hemminki Asta Försti Familial clustering, twin concordance, and identification of high- and low-penetrance cancer predisposition variants support...
Sun Sep 27, 2020 03:00
Cancers, Vol. 12, Pages 2767: Non-Invasive Biomarkers for Early Detection of Breast Cancer Cancers doi: 10.3390/cancers12102767 Authors: Jiawei Li Xin Guan Zhimin Fan Lai-Ming Ching Yan Li Xiaojia Wang Wen-Ming Cao Dong-Xu Liu Breast cancer is the most common cancer in women worldwide. Accurate early diagnosis of breast cancer is critical in the management of the disease. Although mammogram screening has been widely used for breast cancer screening, high false-positive...
Sun Sep 27, 2020 03:00
Cancers, Vol. 12, Pages 2768: Immune Checkpoint Inhibitors in Uro-Oncology: Urgent Call for Biomarkers Cancers doi: 10.3390/cancers12102768 Authors: Renate Pichler Bladder cancer and renal cell carcinoma (RCC) are the second and third most commonly diagnosed cancers in the field of uro-oncology [...]
Sun Sep 27, 2020 03:00
Cancers, Vol. 12, Pages 2766: Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia Cancers doi: 10.3390/cancers12102766 Authors: Sagarajit Mohanty Nidhi Jyotsana Amit Sharma Arnold Kloos Razif Gabdoulline Basem Othman Courteney K. Lai Renate Schottmann Madhvi Mandhania Johannes Schmoellerl Florian Grebien Euan Ramsay Anitha Thomas Hans-Peter Vornlocher Arnold Ganser Felicitas Thol Michael Heuser NUP98-NSD1-positive...
Sat Sep 26, 2020 03:00
Cancers, Vol. 12, Pages 2765: Three-Dimensional Cell Culture Systems in Radiopharmaceutical Cancer Research Cancers doi: 10.3390/cancers12102765 Authors: Alina Doctor Verena Seifert Martin Ullrich Sandra Hauser Jens Pietzsch In preclinical cancer research, three-dimensional (3D) cell culture systems such as multicellular spheroids and organoids are becoming increasingly important. They provide valuable information before studies on animal models begin and, in some cases,...
Fri Sep 25, 2020 03:00
Cancers, Vol. 12, Pages 2764: Under-Replicated DNA: The Byproduct of Large Genomes? Cancers doi: 10.3390/cancers12102764 Authors: Agustina P. Bertolin Jean-Sébastien Hoffmann Vanesa Gottifredi In this review, we provide an overview of how proliferating eukaryotic cells overcome one of the main threats to genome stability: incomplete genomic DNA replication during S phase. We discuss why it is currently accepted that double fork stalling (DFS) events are unavoidable events in higher...
Fri Sep 25, 2020 03:00
Cancers, Vol. 12, Pages 2762: Radiotherapy-Mediated Immunomodulation and Anti-Tumor Abscopal Effect Combining Immune Checkpoint Blockade Cancers doi: 10.3390/cancers12102762 Authors: Xinrui Zhao Chunlin Shao Radiotherapy (RT) is a conventional method for clinical treatment of local tumors，which can induce tumor-specific immune response and cause the shrinkage of primary tumor and distal metastases via mediating tumor infiltration of CD8+ T cells. Ionizing radiation (IR) induced tumor...
Fri Sep 25, 2020 03:00
Cancers, Vol. 12, Pages 2761: Molecular Insights and Emerging Strategies for Treatment of Metastatic Uveal Melanoma Cancers doi: 10.3390/cancers12102761 Authors: Fabiana Mallone Marta Sacchetti Alessandro Lambiase Antonietta Moramarco Uveal melanoma (UM) is the most common intraocular cancer. In recent decades, major advances have been achieved in the diagnosis and prognosis of UM allowing for tailored treatments. However, nearly 50% of patients still develop metastatic disease...
Fri Sep 25, 2020 03:00
Cancers, Vol. 12, Pages 2763: The Role of Daily Adaptive Stereotactic MR-Guided Radiotherapy for Renal Cell Cancer Cancers doi: 10.3390/cancers12102763 Authors: Shyama U. Tetar Omar Bohoudi Suresh Senan Miguel A. Palacios Swie S. Oei Antoinet M. van der Wel Berend J. Slotman R. Jeroen A. van Moorselaar Frank J. Lagerwaard Anna M. E. Bruynzeel Novel magnetic-resonance-guided radiotherapy (MRgRT) permits real-time soft-tissue visualization, respiratory-gated...
Fri Sep 25, 2020 03:00
Cancers, Vol. 12, Pages 2759: Venous Thromboembolism and Its Risk Factors in Children with Acute Lymphoblastic Leukemia in Israel: A Population-Based Study Cancers doi: 10.3390/cancers12102759 Authors: Shlomit Barzilai-Birenboim Ronit Nirel Nira Arad-Cohen Galia Avrahami Miri Ben Harush Assaf Arie Barg Bella Bielorai Ronit Elhasid Gil Gilad Amos Toren Sigal Weinreb Shai Izraeli Sarah Elitzur Venous thromboembolism (VTE) is a serious complication of...
Fri Sep 25, 2020 03:00
Cancers, Vol. 12, Pages 2760: Cancer and pH Dynamics: Transcriptional Regulation, Proteostasis, and the Need for New Molecular Tools Cancers doi: 10.3390/cancers12102760 Authors: Brandon J. Czowski Ricardo Romero-Moreno Keelan J. Trull Katharine A. White An emerging hallmark of cancer cells is dysregulated pH dynamics. Recent work has suggested that dysregulated intracellular pH (pHi) dynamics enable diverse cancer cellular behaviors at the population level, including cell proliferation,...
Fri Sep 25, 2020 03:00
Cancers, Vol. 12, Pages 2757: AXL Inactivation Inhibits Mesothelioma Growth and Migration via Regulation of p53 Expression Cancers doi: 10.3390/cancers12102757 Authors: Wei Song Hao Wang Minmin Lu Xinxin Ni Nacef Bahri Shuihao Zhu Limin Chen Yuehong Wu Jieqiong Qiu Jonathan A. Fletcher Wen-Bin Ou Malignant mesothelioma is a locally aggressive and highly lethal neoplasm. Dysregulation and activation of Gas6/AXL tyrosine kinase signaling are associated with...
Fri Sep 25, 2020 03:00
Cancers, Vol. 12, Pages 2758: ITPKC as a Prognostic and Predictive Biomarker of Neoadjuvant Chemotherapy for Triple Negative Breast Cancer Cancers doi: 10.3390/cancers12102758 Authors: Masanori Oshi Stephanie Newman Vijayashree Murthy Yoshihisa Tokumaru Li Yan Ryusei Matsuyama Itaru Endo Kazuaki Takabe Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with higher mortality than the others. Pathological complete response (pCR) to...
Fri Sep 25, 2020 03:00
Cells, Vol. 9, Pages 2178: 3D Stem Cell Culture Cells doi: 10.3390/cells9102178 Authors: Joni H. Ylostalo Much interest has been directed towards stem cells, both in basic and translational research, to understand basic stem cell biology and to develop new therapies for many disorders. In general, stem cells can be cultured with relative ease, however, most common culture methods for stem cells employ 2D techniques using plastic. These cultures do not well represent the stem cell niches...
Sun Sep 27, 2020 03:00
Cells, Vol. 9, Pages 2181: Epitranscriptomics of Mammalian Mitochondrial Ribosomal RNA Cells doi: 10.3390/cells9102181 Authors: Laptev Dontsova Sergiev Modified nucleotides are present in all ribosomal RNA molecules. Mitochondrial ribosomes are unique to have a set of methylated residues that includes universally conserved ones, those that could be found either in bacterial or in archaeal/eukaryotic cytosolic ribosomes and those that are present exclusively in mitochondria....
Sun Sep 27, 2020 03:00
Cells, Vol. 9, Pages 2180: Diverse Defenses: A Perspective Comparing Dipteran Piwi-piRNA Pathways Cells doi: 10.3390/cells9102180 Authors: Stephanie Gamez Satyam Srivastav Omar S. Akbari Nelson C. Lau Animals face the dual threat of virus infections hijacking cellular function and transposons proliferating in germline genomes. For insects, the deeply conserved RNA interference (RNAi) pathways and other chromatin regulators provide an important line of defense against both viruses...
Sun Sep 27, 2020 03:00
Cells, Vol. 9, Pages 2179: Serum Levels of Bone Morphogenetic Proteins 2 and 4 in Patients with Acute Myocardial Infarction Cells doi: 10.3390/cells9102179 Authors: Maria Kercheva Anna M. Gusakova Tamara R. Ryabova Tatiana E. Suslova Julia Kzhyshkowska Vyacheslav V. Ryabov Background: Bone morphogenetic proteins-2 and -4 (BMPs) have been implicated in left ventricular remodeling (LVR) processes such as an inflammation and fibrogenesis. We hypothesized that this knowledge...
Sun Sep 27, 2020 03:00
Cells, Vol. 9, Pages 2176: Neuron-Glia Interactions in Neurodevelopmental Disorders Cells doi: 10.3390/cells9102176 Authors: Yoo Sung Kim Juwon Choi Bo-Eun Yoon Recent studies have revealed synaptic dysfunction to be a hallmark of various psychiatric diseases, and that glial cells participate in synapse formation, development, and plasticity. Glial cells contribute to neuroinflammation and synaptic homeostasis, the latter being essential for maintaining the physiological function...
Sun Sep 27, 2020 03:00
Cells, Vol. 9, Pages 2177: GPR91 Receptor Mediates Protection against Doxorubicin-Induced Cardiotoxicity without Altering Its Anticancer Efficacy. An In Vitro Study on H9C2 Cardiomyoblasts and Breast Cancer-Derived MCF-7 Cells Cells doi: 10.3390/cells9102177 Authors: Matthieu Dallons Esma Alpan Corentin Schepkens Vanessa Tagliatti Jean-Marie Colet Doxorubicin (DOX) is an anticancer drug widely used in oncology, especially for breast cancer. The main limitation of DOX treatment...
Sun Sep 27, 2020 03:00
Cells, Vol. 9, Pages 2173: Astrocytic Factors Controlling Synaptogenesis: A Team Play Cells doi: 10.3390/cells9102173 Authors: Giuliana Fossati Michela Matteoli Elisabetta Menna Astrocytes are essential players in brain circuit development and homeostasis, controlling many aspects of synapse formation, function, plasticity and elimination both during development and adulthood. Accordingly, alterations in astrocyte morphogenesis and physiology may severely affect proper brain development,...
Sat Sep 26, 2020 03:00
Cells, Vol. 9, Pages 2174: Sex-Specific Control of Muscle Mass: Elevated IGFBP Proteolysis and Reductions of IGF-1 Levels Are Associated with Substantial Loss of Carcass Weight in Male DU6PxIGFBP-2 Transgenic Mice Cells doi: 10.3390/cells9102174 Authors: Daniela Ohde Michael Walz Christina Walz Antonia Noce Julia Brenmoehl Martina Langhammer Andreas Hoeflich In farmed animals, carcass weight represents an important economic trait. Since we had demonstrated that IGFBP-2...
Sat Sep 26, 2020 03:00
Cells, Vol. 9, Pages 2172: AQP2: Mutations Associated with Congenital Nephrogenic Diabetes Insipidus and Regulation by Post-Translational Modifications and Protein-Protein Interactions Cells doi: 10.3390/cells9102172 Authors: Chao Gao Paul J. Higgins Wenzheng Zhang As a rare hereditary disease, congenital nephrogenic diabetes insipidus (NDI) is clinically characterized by polyuria with hyposthenuria and polydipsia. NDI results from collecting duct principal cell hyporesponsiveness...
Sat Sep 26, 2020 03:00
Cells, Vol. 9, Pages 2175: Integrated Transcriptome and Proteome Analyses Reveal the Regulatory Role of miR-146a in Human Limbal Epithelium via Notch Signaling Cells doi: 10.3390/cells9102175 Authors: Adam J. Poe Mangesh Kulkarni Aleksandra Leszczynska Jie Tang Ruchi Shah Yasaman Jami-Alahmadi Jason Wang Andrei A. Kramerov James Wohlschlegel Vasu Punj Alexander V. Ljubimov Mehrnoosh Saghizadeh MiR-146a is upregulated in the stem cell-enriched limbal region...
Sat Sep 26, 2020 03:00
Cells, Vol. 9, Pages 2169: Tick-Borne Encephalitis: A Differential Pattern of Intrathecal Humoral Immune Response and Inflammatory Cell Composition Compared with Other Viral CNS Infections Cells doi: 10.3390/cells9102169 Authors: Makbule Senel Daniel Rapp Benjamin Mayer Sarah Jesse Sigurd D. Süssmuth Markus Otto Jan Lewerenz Hayrettin Tumani To investigate whether and how cerebrospinal fluid (CSF) findings can contribute to distinguish tick-borne encephalitis (TBE)...
Fri Sep 25, 2020 03:00
Cells, Vol. 9, Pages 2170: Epac1 Is Crucial for Maintenance of Endothelial Barrier Function through A Mechanism Partly Independent of Rac1 Cells doi: 10.3390/cells9102170 Authors: Alexander García-Ponce Katharina Schuster Stein-Ove Døskeland Rolf K. Reed Fitz-Roy E. Curry Jens Waschke Mariya Y. Radeva Epac1 (exchange protein activated by cAMP) stabilizes the endothelial barrier, but detailed studies are limited by the side effects of pharmacological Epac1 modulators...
Fri Sep 25, 2020 03:00
Cells, Vol. 9, Pages 2171: In Situ Gel Incorporating Disulfiram Nanoparticles Rescues the Retinal Dysfunction via ATP Collapse in Otsuka Long–Evans Tokushima Fatty Rats Cells doi: 10.3390/cells9102171 Authors: Saori Deguchi Fumihiko Ogata Mizuki Yamaguchi Misa Minami Hiroko Otake Kazutaka Kanai Naohito Kawasaki Noriaki Nagai We attempted to design an ophthalmic in situ gel formulation incorporating disulfiram (DIS) nanoparticles (Dis-NPs/ISG) and demonstrated the...
Fri Sep 25, 2020 03:00
Cells, Vol. 9, Pages 2168: Rapid Detection of Free Cancer Cells in Intraoperative Peritoneal Lavage Using One-Step Nucleic Acid Amplification (OSNA) in Gastric Cancer Patients Cells doi: 10.3390/cells9102168 Authors: Katarzyna Gęca Karol Rawicz-Pruszyński Jerzy Mielko Radosław Mlak Katarzyna Sędłak Wojciech P. Polkowski Cytokeratin-19 (CK19) has been proven to be commonly expressed by cancer cells in a variety of solid tumors and may serve as a suitable marker of metastases...
Fri Sep 25, 2020 03:00
Cells, Vol. 9, Pages 2167: Rho GTPases: Big Players in Breast Cancer Initiation, Metastasis and Therapeutic Responses Cells doi: 10.3390/cells9102167 Authors: Brock Humphries Zhishan Wang Chengfeng Yang Rho GTPases, a family of the Ras GTPase superfamily, are key regulators of the actin cytoskeleton. They were originally thought to primarily affect cell migration and invasion; however, recent advances in our understanding of the biology and function of Rho GTPases have demonstrated...
Fri Sep 25, 2020 03:00
Cells, Vol. 9, Pages 2166: Presenilin-2 and Calcium Handling: Molecules, Organelles, Cells and Brain Networks Cells doi: 10.3390/cells9102166 Authors: Paola Pizzo Emy Basso Riccardo Filadi Elisa Greotti Alessandro Leparulo Diana Pendin Nelly Redolfi Michela Rossini Nicola Vajente Tullio Pozzan Cristina Fasolato Presenilin-2 (PS2) is one of the three proteins that are dominantly mutated in familial Alzheimer’s disease (FAD). It forms the catalytic...
Fri Sep 25, 2020 03:00
Chemosensors, Vol. 8, Pages 92: Electrical and Humidity-Sensing Properties of Impedance-Type Humidity Sensors that Were Made of Ag Microwires/PPy/SnO2 Ternary Composites Chemosensors doi: 10.3390/chemosensors8040092 Authors: Pi-Guey Su Ping-Hsiang Lu Impedance-type humidity sensors were fabricated via one-step UV-irradiation photopolymerization of Ag microwires (Ag MWs), polypyrrole (PPy) and SnO2 ternary composite (Ag MWs/PPy/SnO2) films on an alumina substrate. X-ray diffractometry...
Sun Sep 27, 2020 03:00
Chemosensors, Vol. 8, Pages 91: Enhancement of Characteristics of Field Asymmetric Ion Mobility Spectrometer with Laser Ionization for Detection of Explosives in Vapor Phase Chemosensors doi: 10.3390/chemosensors8040091 Authors: Vitalii A. Kostarev Gennadii E. Kotkovskii Alexander A. Chistyakov Artem E. Akmalov Ion mobility spectrometry instrumentation today is widespread in the area of transport security and counterterrorism. This method of detection of explosive substances...
Sun Sep 27, 2020 03:00
Chemosensors, Vol. 8, Pages 90: Electrochemical Hybrid Methods and Sensors for Antioxidant/Oxidant Activity Monitoring and Their Use as a Diagnostic Tool of Oxidative Stress: Future Perspectives and Challenges Chemosensors doi: 10.3390/chemosensors8040090 Authors: Khiena Z. Brainina Yan E. Kazakov The terminology used in electrochemical methods which are used to generate the measured signal in antioxidant/oxidant activity (AOA/OA) sensors is briefly considered. The review presents...
Sat Sep 26, 2020 03:00
Chemosensors, Vol. 8, Pages 89: RH Sensing by Means of TiO2 Nanoparticles: A Comparison among Different Sensing Techniques Based on Modeling and Chemical/Physical Interpretation Chemosensors doi: 10.3390/chemosensors8040089 Authors: Irene Cappelli Ada Fort Anna Lo Grasso Enza Panzardi Marco Mugnaini Valerio Vignoli TiO2 nanoparticles coating has been proven to be an extremely performing sensing material for relative humidity (RH) measurements. The chemical activity of...
Fri Sep 25, 2020 03:00
Children, Vol. 7, Pages 153: Nebulizer Care and Inhalation Technique in Children with Cystic Fibrosis Children doi: 10.3390/children7100153 Authors: Argyri Petrocheilou Athanasios G. Kaditis Evgenia Troupi Ioanna Loukou Nebulizers are used by the great majority of cystic fibrosis patients for delivery of cornerstone treatments. Inhalation technique and adequate disinfection and maintenance are important for optimizing medication delivery. In this study, inhalation technique...
Sun Sep 27, 2020 03:00
Children, Vol. 7, Pages 152: Global Dietary Patterns and Functional Gastrointestinal Disorders Children doi: 10.3390/children7100152 Authors: Cara Hannah Axelrod Miguel Saps Functional Gastrointestinal Disorders (FGIDs) are common. In the United States alone, approximately 25 million Americans are estimated to have at least one FGID. Nonpharmacological treatment options include psychological/behavioral approaches, and dietary interventions that can vary across countries. The aim of...
Sun Sep 27, 2020 03:00
Children, Vol. 7, Pages 151: An Evaluation of the Implementation of a UK School-Based Running Program Children doi: 10.3390/children7100151 Authors: Anna E. Chalkley Ash C. Routen Jo P. Harris Lorraine A. Cale Trish Gorely Lauren B. Sherar The adoption of school-based running programs has rapidly increased over the last five years in the UK and globally. However, there is currently a lack of information on how these initiatives are implemented, and whether they are generalizable...
Fri Sep 25, 2020 03:00
Children, Vol. 7, Pages 150: Genetic and Environmental Risk Factors for Isolated Hemangiomas in Infants Children doi: 10.3390/children7100150 Authors: Anna Materna-Kiryluk Katarzyna Wiśniewska Barbara Więckowska Katarzyna Wróblewska-Seniuk Beata Jaroszewska-Świątek Ewa Helwich Anna Latos-Bieleńska The goal of this analysis is to identify risk factors for infantile hemangiomas (IH) to better delineate hemangioma predisposition. We analyzed live birth children with isolated...
Fri Sep 25, 2020 03:00
Climate, Vol. 8, Pages 105: Expected Impacts of Mixing European Beech with Silver Fir on Regional Air Quality and Radiation Balance Climate doi: 10.3390/cli8100105 Authors: Boris Bonn Jürgen Kreuzwieser Ruth-Kristina Magh Heinz Rennenberg Dirk Schindler Dominik Sperlich Raphael Trautmann Rasoul Yousefpour Rüdiger Grote The anticipated climate change during the next decades is posing crucial challenges to ecosystems. In order to decrease the vulnerability of forests,...
Sat Sep 26, 2020 03:00
Cosmetics, Vol. 7, Pages 76: Skin Protective Activity of LactoSporin-the Extracellular Metabolite from Bacillus Coagulans MTCC 5856 Cosmetics doi: 10.3390/cosmetics7040076 Authors: Muhammed Majeed Shaheen Majeed Kalyanam Nagabhushanam Lincy Lawrence Sivakumar Arumugam Lakshmi Mundkur Background: Probiotics and their products are increasingly used in skincare in recent years. Postbiotics are defined as any substance derived through the metabolic activity of a probiotic...
Sun Sep 27, 2020 03:00
Cosmetics, Vol. 7, Pages 75: Applications of Natural, Semi-Synthetic, and Synthetic Polymers in Cosmetic Formulations Cosmetics doi: 10.3390/cosmetics7040075 Authors: Thais F. R. Alves Margreet Morsink Fernando Batain Marco V. Chaud Taline Almeida Dayane A. Fernandes Classius F. da Silva Eliana B. Souto Patricia Severino Cosmetics composed of synthetic and/or semi-synthetic polymers, associated or not with natural polymers, exhibit a dashing design, with thermal...
Fri Sep 25, 2020 03:00
Diagnostics, Vol. 10, Pages 759: Phenotypic and Genotypic Analysis of Resistant Helicobacter pylori Strains Isolated from Children with Gastrointestinal Diseases Diagnostics doi: 10.3390/diagnostics10100759 Authors: Biernat Bińkowska Łaczmański Biernat Krzyżek Gościniak Antibiotic resistance of Helicobacter pylori is currently a global issue. The aim of this study was to analyze actual antibiotic resistance rates of H. pylori strains isolated from children with primary...
Sun Sep 27, 2020 03:00
Diagnostics, Vol. 10, Pages 758: Coagulation Profiles of Pulmonary Arterial Hypertension Patients, Assessed by Non-Conventional Hemostatic Tests and Markers of Platelet Activation and Endothelial Dysfunction Diagnostics doi: 10.3390/diagnostics10100758 Authors: Eleni Vrigkou Argyrios E. Tsantes Petros Kopterides Stylianos E. Orfanos Apostolos Armaganidis Eirini Maratou Evdoxia Rapti Athanasios Pappas Andreas G. Tsantes Iraklis Tsangaris Many pathophysiologic...
Sun Sep 27, 2020 03:00
Diagnostics, Vol. 10, Pages 757: Nitrogen-Doped Titanium Dioxide Nanoparticles Modified by An Electron Beam for Improving Human Breast Cancer Detection by Raman Spectroscopy: A Preliminary Study Diagnostics doi: 10.3390/diagnostics10100757 Authors: Jakub Surmacki Titanium dioxide (TiO2) is commonly used as a pigment in paints, paper products, polymer compositions, and cosmetic products, and even as a food additive or drug coating material. In recent times, it has also been used in photovoltaic...
Sat Sep 26, 2020 03:00
Diagnostics, Vol. 10, Pages 756: Image Quality and Interpretation of [18F]-FES-PET: Is There Any Effect of Food Intake? Diagnostics doi: 10.3390/diagnostics10100756 Authors: Boers Giatagana Schröder Hospers de Vries Glaudemans Background: High physiological 16α-[18F]-fluoro-17β-estradiol ([18F]-FES) uptake in the abdomen is a limitation of this positron emission tomography (PET) tracer. Therefore, we investigated the effect of food intake prior...
Sat Sep 26, 2020 03:00
Diagnostics, Vol. 10, Pages 755: Small Fibre Involvement in Multifocal Motor Neuropathy Explored with Sudoscan: A Single-Centre Experience Diagnostics doi: 10.3390/diagnostics10100755 Authors: Marco Luigetti Silvia Giovannini Angela Romano Giulia Bisogni Francesco Barbato Andrea Di Paolantonio Serenella Servidei Giuseppe Granata Mario Sabatelli Objective: Multifocal motor neuropathy (MMN) is a rare inflammatory neuropathy, clinically characterized by exclusive...
Sat Sep 26, 2020 03:00
Diagnostics, Vol. 10, Pages 754: Diagnostic Performance of 18F-FDG PET/CT in Native Valve Endocarditis: Systematic Review and Bivariate Meta-Analysis Diagnostics doi: 10.3390/diagnostics10100754 Authors: Christel H. Kamani Gilles Allenbach Mario Jreige Anna G. Pavon Marie Meyer Nathalie Testart Maria Firsova Victor Fernandes Vieira Sarah Boughdad Marie Nicod Lalonde Niklaus Schaefer Benoit Guery Pierre Monney John O. Prior Giorgio Treglia Background:...
Fri Sep 25, 2020 03:00
Diagnostics, Vol. 10, Pages 753: Reducing the Breast Cancer Risk and Radiation Dose of Radiography for Scoliosis in Children: A Phantom Study Diagnostics doi: 10.3390/diagnostics10100753 Authors: Manami Nemoto Koichi Chida Full-spinal radiographs (FRs) are often the first choice of imaging modality in the investigation of scoliosis. However, FRs are strongly related to breast cancer occurrence due to multiple large-field radiographic examinations taken during childhood and adolescence,...
Fri Sep 25, 2020 03:00
Diagnostics, Vol. 10, Pages 750: Scale-Up Evaluation of a Composite Tumor Marker Assay for the Early Detection of Renal Cell Carcinoma Diagnostics doi: 10.3390/diagnostics10100750 Authors: Dong Su Kim Won Sik Ham Won Sik Jang Kang Su Cho Young Deuk Choi Suki Kang Bora Kim Kook Jin Kim Eun Ji Lim Sun Young Rha Ja Hyeon Ku Cheol Kwak Hyeon Hoe Kim Chang Wook Jeong Nam Hoon Cho The early detection of renal cell carcinoma (RCC) using tumor markers...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου