IJERPH, Vol. 17, Pages 7014: Is a View of Green Spaces from Home Associated with a Lower Risk of Anxiety and Depression? International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197014 Authors: Olta Braçe Marco Garrido-Cumbrera Ronan Foley José Correa-Fernández Gina Suárez-Cáceres Raffaele Lafortezza Although a large body of research supports the theory that exposure to nature results in mental health benefits, research evidence on the effects...
Fri Sep 25, 2020 03:00
IJERPH, Vol. 17, Pages 7012: Chronic Facial Pain: Trigeminal Neuralgia, Persistent Idiopathic Facial Pain, and Myofascial Pain Syndrome—An Evidence-Based Narrative Review and Etiological Hypothesis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197012 Authors: Robert Gerwin Trigeminal neuralgia (TN), the most common form of severe facial pain, may be confused with an ill-defined persistent idiopathic facial pain (PIFP). Facial pain is reviewed...
Fri Sep 25, 2020 03:00
IJERPH, Vol. 17, Pages 7013: Testing the Intermediary Role of Perceived Stress in the Relationship between Mindfulness and Burnout Subtypes in a Large Sample of Spanish University Students International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197013 Authors: David Martínez-Rubio Juan P. Sanabria-Mazo Albert Feliu-Soler Ariadna Colomer-Carbonell Cristina Martínez-Brotóns Silvia Solé Cristina Escamilla Elisa Giménez-Fita Yolanda Moreno...
Fri Sep 25, 2020 03:00
IJERPH, Vol. 17, Pages 7011: Infantile Colic—The Perspective of German and Polish Pediatricians in 2020 International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197011 Authors: Henning Sommermeyer Hanna Krauss Zuzanna Chęcińska-Maciejewska Marcin Pszczola Jacek Piątek The objective of the study was to characterize how infantile colic is perceived and managed by German and Polish pediatricians. Data in both countries were collected by using a...
Fri Sep 25, 2020 03:00
IJERPH, Vol. 17, Pages 7010: Rasch Analysis of the Korean Parenting Stress Index Short Form (K-PSI-SF) in Mothers of Children with Cerebral Palsy International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17197010 Authors: Eun-Young Park Soojung Chae The purpose of this study was to investigate the psychometric characteristics of the Korean Parenting Stress Index Short Form (K-PSI-SF) for mothers of children with cerebral palsy (CP) by using a Rasch analysis....
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7144: Review on Structures of Pesticide Targets International Journal of Molecular Sciences doi: 10.3390/ijms21197144 Authors: Xiangyang Li Xueqing Yang Xiaodong Zheng Miao Bai Deyu Hu Molecular targets play important roles in agrochemical discovery. Numerous pesticides target the key proteins in pathogens, insect, or plants. Investigating ligand-binding pockets and/or active sites in the proteins’ structures is usually the first step in designing...
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IJMS, Vol. 21, Pages 7143: Regenerative Response of Degenerate Human Nucleus Pulposus Cells to GDF6 Stimulation International Journal of Molecular Sciences doi: 10.3390/ijms21197143 Authors: Hodgkinson Gilbert Pandya Diwan Hoyland Richardson Growth differentiation factor (GDF) family members have been implicated in the development and maintenance of healthy nucleus pulposus (NP) tissue, making them promising therapeutic candidates for treatment of intervertebral...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7141: The Hirudo Medicinalis Microbiome Is a Source of New Antimicrobial Peptides International Journal of Molecular Sciences doi: 10.3390/ijms21197141 Authors: Grafskaia Pavlova Babenko Latsis Malakhova Lavrenova Bashkirov Belousov Klinov Lazarev Antimicrobial peptides (AMPs) are considered a promising new class of anti-infectious agents. This study reports new antimicrobial peptides derived from the Hirudo medicinalis microbiome...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7142: Calmodulin-Like (CML) Gene Family in Medicago truncatula: Genome-Wide Identification, Characterization and Expression Analysis International Journal of Molecular Sciences doi: 10.3390/ijms21197142 Authors: Qiguo Sun Shuhan Yu Zhenfei Guo Calcium is an important second messenger in mediating adaptation responses of plants to abiotic and biotic stresses. Calmodulin-like (CML) protein is an important calcium-signaling protein that can sense and decode Ca2+...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7139: Spatial and Temporal Changes in PD-L1 Expression in Cancer: The Role of Genetic Drivers, Tumor Microenvironment and Resistance to Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21197139 Authors: Shklovskaya Rizos Immunotherapies blocking immune inhibitory receptors programmed cell death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) on T-cells have dramatically improved patient outcomes in a range of advanced cancers....
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7140: Expression, Regulation and Function of microRNA as Important Players in the Transition of MDS to Secondary AML and Their Cross Talk to RNA-Binding Proteins International Journal of Molecular Sciences doi: 10.3390/ijms21197140 Authors: Bauer Vaxevanis Heimer Al-Ali Jaekel Bachmann Wickenhauser Seliger Myelodysplastic syndromes (MDS), heterogeneous diseases of hematopoietic stem cells, exhibit a significant risk of progression to...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7138: Weak Ultraviolet B Enhances the Mislocalization of Claudin-1 Mediated by Nitric Oxide and Peroxynitrite Production in Human Keratinocyte-Derived HaCaT Cells International Journal of Molecular Sciences doi: 10.3390/ijms21197138 Authors: Mao Kobayashi Shokoku Shu Kana Marunaka Toshiyuki Matsunaga Akira Ikari A tight junction (TJ) makes a physical barrier in the epidermal cells of skin. Ultraviolet (UV) light may disrupt the TJ barrier, but the mechanism...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7137: Nephrotoxicity Evaluation of Indium Phosphide Quantum Dots with Different Surface Modifications in BALB/c Mice International Journal of Molecular Sciences doi: 10.3390/ijms21197137 Authors: Li Li Tingting Chen Zhiwen Yang Yajing Chen Dongmeng Liu Huiyu Xiao Maixian Liu Kan Liu Jiangyao Xu Shikang Liu Xiaomei Wang Guimiao Lin Gaixia Xu InP QDs have shown a great potential as cadmium-free QDs alternatives in biomedical applications....
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7136: Functional Characterization of RNA Silencing Suppressor P0 from Pea Mild Chlorosis Virus International Journal of Molecular Sciences doi: 10.3390/ijms21197136 Authors: Qian Sun Tao Zhuo Tianyu Zhao Cuiji Zhou Yuanyuan Li Ying Wang Dawei Li Jialin Yu Chenggui Han To counteract host antiviral RNA silencing, plant viruses encode numerous viral suppressors of RNA silencing (VSRs). P0 proteins have been identified as VSRs in many poleroviruses....
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7134: Physiologic and Metabolic Changes in Crepidiastrum denticulatum According to Different Energy Levels of UV-B Radiation International Journal of Molecular Sciences doi: 10.3390/ijms21197134 Authors: Song-Yi Park Mee-Youn Lee Choong-Hwan Lee Myung-Min Oh Ultraviolet B (UV-B) light, as a physical elicitor, can promote the secondary metabolites biosynthesis in plants. We investigated effects of different energy levels of UV-B radiation on growth and bioactive...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7133: How Does Replacement of the Axial Histidine Ligand in Cytochrome c Peroxidase by Nδ-Methyl Histidine Affect Its Properties and Functions? A Computational Study International Journal of Molecular Sciences doi: 10.3390/ijms21197133 Authors: Calvin W. Z. Lee M. Qadri E. Mubarak Anthony P. Green Sam P. de Visser Heme peroxidases have important functions in nature related to the detoxification of H2O2. They generally undergo a catalytic cycle where, in...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7135: A Survey of Barley PIP Aquaporin Ionic Conductance Reveals Ca2+-Sensitive HvPIP2;8 Na+ and K+ Conductance International Journal of Molecular Sciences doi: 10.3390/ijms21197135 Authors: Sen Thi Huong Tran Shahin Imran Tomoaki Horie Jiaen Qiu Samantha McGaughey Caitlin S. Byrt Stephen D. Tyerman Maki Katsuhara Some plasma membrane intrinsic protein (PIP) aquaporins can facilitate ion transport. Here we report that one of the 12 barley PIPs...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7131: Factors That Affect the Enlargement of Bacterial Protoplasts and Spheroplasts International Journal of Molecular Sciences doi: 10.3390/ijms21197131 Authors: Nishida Cell enlargement is essential for the microinjection of various substances into bacterial cells. The cell wall (peptidoglycan) inhibits cell enlargement. Thus, bacterial protoplasts/spheroplasts are used for enlargement because they lack cell wall. Though bacterial species that are capable of gene...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7132: Role of Plasma Gelsolin Protein in the Final Stage of Erythropoiesis and in Correction of Erythroid Dysplasia In Vitro International Journal of Molecular Sciences doi: 10.3390/ijms21197132 Authors: So Yeon Han Eun Mi Lee Suyeon Kim Amy M. Kwon Eun Jung Baek Gelsolin, an actin-remodeling protein, is involved in cell motility, cytoskeletal remodeling, and cytokinesis and is abnormally expressed in many cancers. Recently, human recombinant plasma gelsolin...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7130: Modular Chitosan-Based Adsorbents for Tunable Uptake of Sulfate from Water International Journal of Molecular Sciences doi: 10.3390/ijms21197130 Authors: Steiger Wilson The context of this study responds to the need for sorbent technology development to address the controlled removal of inorganic sulfate (SO42−) from saline water and the promising potential of chitosan as a carrier system for organosulfates in pharmaceutical and nutraceutical...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7128: A Fluorescence Polarization-Based High-Throughput Screen to Identify the First Small-Molecule Modulators of the Human Adenylyltransferase HYPE/FICD International Journal of Molecular Sciences doi: 10.3390/ijms21197128 Authors: Ali Camara Alyssa George Evan Hebner Anika Mahmood Jashun Paluru Seema Mattoo The covalent transfer of the AMP portion of ATP onto a target protein—termed adenylylation or AMPylation—by the human Fic...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7129: Analysis of the Codon Usage Pattern of HA and NA Genes of H7N9 Influenza A Virus International Journal of Molecular Sciences doi: 10.3390/ijms21197129 Authors: Jiumeng Sun Wen Zhao Ruyi Wang Wenyan Zhang Gairu Li Meng Lu Yuekun Shao Yichen Yang Ningning Wang Qi Gao Shuo Su Novel H7N9 influenza virus transmitted from birds to human and, since March 2013, it has caused five epidemic waves in China. Although the evolution of H7N9...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7127: Emerging Roles of BRD7 in Pathophysiology International Journal of Molecular Sciences doi: 10.3390/ijms21197127 Authors: Sang Won Park Junsik M. Lee Bromodomain is a conserved structural module found in many chromatin-associated proteins. Bromodomain-containing protein 7 (BRD7) is a member of the bromodomain-containing protein family, and was discovered two decades ago as a protein that is downregulated in nasopharyngeal carcinoma. Since then, BRD7 has been...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7126: The Cotton BEL1-Like Transcription Factor GhBLH7-D06 Negatively Regulates the Defense Response against Verticillium dahliae International Journal of Molecular Sciences doi: 10.3390/ijms21197126 Authors: Qiang Ma Nuohan Wang Liang Ma Jianhua Lu Hantao Wang Congcong Wang Shuxun Yu Hengling Wei Verticillium wilt will seriously affect cotton yield and fiber quality. BEL1-Like transcription factors are involved in the regulation of secondary...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7124: The Impact of Controlled Ovarian Stimulation Hormones on the Metabolic State and Endocannabinoid System of Human Cumulus Cells International Journal of Molecular Sciences doi: 10.3390/ijms21197124 Authors: Valentina Notarstefano Giorgia Gioacchini Elisabetta Giorgini Nina Montik Andrea Ciavattini Anna Rita Polidori Fulvia Antonia Candela Lisa Vaccari Maurizio Cignitti Oliana Carnevali Different Follicle Stimulating Hormone (FSH) formulation...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7125: Gold Nanoparticle Formation via X-ray Radiolysis Investigated with Time-Resolved X-ray Liquidography International Journal of Molecular Sciences doi: 10.3390/ijms21197125 Authors: Hosung Ki Sungjun Park Seunghwan Eom Jain Gu Siin Kim Changwon Kim Chi Woo Ahn Minseo Choi Sena Ahn Doo-Sik Ahn Jungkweon Choi Mu-Hyun Baik Hyotcherl Ihee We report the generation of gold nanoparticles (AuNPs) from the aqueous solution of chloro(2,2′,2″-terpyridine)gold(III)...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7122: The Brain–Gut–Microbiome Axis in Psychiatry International Journal of Molecular Sciences doi: 10.3390/ijms21197122 Authors: Seung-Ho Jang Young Sup Woo Sang-Yeol Lee Won-Myong Bahk Beginning with the concept of the brain–gut axis, the importance of the interaction between the brain and the gastrointestinal tract has been extended to the microbiome with increasing clinical applications. With the recent development of various techniques for...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7119: Potential Role of Lycopene in the Prevention of Postmenopausal Bone Loss: Evidence from Molecular to Clinical Studies International Journal of Molecular Sciences doi: 10.3390/ijms21197119 Authors: Umani S. Walallawita Frances M. Wolber Ayelet Ziv-Gal Marlena C. Kruger Julian A. Heyes Osteoporosis is a metabolic bone disease characterized by reduced bone mineral density, which affects the quality of life of the aging population. Furthermore, disruption...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7123: Heme Oxygenase 1 and 2 Differentially Regulate Glucose Metabolism and Adipose Tissue Mitochondrial Respiration: Implications for Metabolic Dysregulation International Journal of Molecular Sciences doi: 10.3390/ijms21197123 Authors: Hongwei Yao Abigail L. Peterson Jie Li Haiyan Xu Phyllis A. Dennery Heme oxygenase (HO) consists of inducible (HO-1) and constitutive (HO-2) isoforms that are encoded by Hmox1 and Hmox2 genes, respectively. As an anti-inflammatory...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7118: Paediatric Formulation: Design and Development International Journal of Molecular Sciences doi: 10.3390/ijms21197118 Authors: Antonio Lopalco Nunzio Denora The development of medicines designed for children can be challenging since this distinct patient population requires specific needs. A formulation designed for paediatric patients must consider the following aspects: patient population variability; dose flexibility; route of administration; patient compliance;...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7121: Long Noncoding RNA PVT1 Is Regulated by Bromodomain Protein BRD4 in Multiple Myeloma and Is Associated with Disease Progression International Journal of Molecular Sciences doi: 10.3390/ijms21197121 Authors: Hiroshi Handa Kazuki Honma Tsukasa Oda Nobuhiko Kobayashi Yuko Kuroda Kei Kimura-Masuda Saki Watanabe Rei Ishihara Yuki Murakami Yuta Masuda Ken-ichi Tahara Hisashi Takei Tetsuhiro Kasamatsu Takayuki Saitoh Hirokazu Murakami...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7120: Transcriptome and Gene Fusion Analysis of Synchronous Lesions Reveals lncMRPS31P5 as a Novel Transcript Involved in Colorectal Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21197120 Authors: Anna Panza Stefano Castellana Giuseppe Biscaglia Ada Piepoli Luca Parca Annamaria Gentile Anna Latiano Tommaso Mazza Francesco Perri Angelo Andriulli Orazio Palmieri Fusion genes and epigenetic regulators (i.e., miRNAs...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7117: MicroRNAs: As Critical Regulators of Tumor- Associated Macrophages International Journal of Molecular Sciences doi: 10.3390/ijms21197117 Authors: Bilash Chatterjee Priyanka Saha Subhankar Bose Devendra Shukla Nabanita Chatterjee Sanjay Kumar Prem Prakash Tripathi Amit Kumar Srivastava Emerging shreds of evidence suggest that tumor-associated macrophages (TAMs) modulate various hallmarks of cancer during tumor progression. Tumor microenvironment...
Sun Sep 27, 2020 03:00
IJMS, Vol. 21, Pages 7116: Metabolomic Analysis Reveals Changes in Preimplantation Embryos Following Fresh or Vitrified Transfer International Journal of Molecular Sciences doi: 10.3390/ijms21197116 Authors: Ximo Garcia-Dominguez Gianfranco Diretto Sarah Frusciante José Salvador Vicente Francisco Marco-Jiménez Although assisted reproduction technologies (ARTs) are recognised as safe, and most of the offspring seem apparently healthy, there is clear evidence that ARTs are...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7115: Acute Kidney Injury in Septic Patients Treated by Selected Nephrotoxic Antibiotic Agents—Pathophysiology and Biomarkers—A Review International Journal of Molecular Sciences doi: 10.3390/ijms21197115 Authors: Nadezda Petejova Arnost Martinek Josef Zadrazil Marcela Kanova Viktor Klementa Radka Sigutova Ivana Kacirova Vladimir Hrabovsky Zdenek Svagera David Stejskal Acute kidney injury is a common complication in critically ill patients...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7114: Alumina Ceramic Exacerbates the Inflammatory Disease by Activation of Macrophages and T Cells International Journal of Molecular Sciences doi: 10.3390/ijms21197114 Authors: Seong-Min Lim Juyoung Hwang Hae-Bin Park Chan Ho Park Jun-O Jin (1) Background: Aluminum oxide (Al2O3) ceramic is one of the materials used for artificial joints, and it has been known that their fine particles (FPs) are provided by the wear of the ceramic. Al2O3 FPs have been...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7112: Gross Chromosomal Rearrangements in Kluyveromyces marxianus Revealed by Illumina and Oxford Nanopore Sequencing International Journal of Molecular Sciences doi: 10.3390/ijms21197112 Authors: Ding Macdonald Smith Hutchison III Merryman Michael Abramson Kannan Liang Gill Gibson Glass Kluyveromyces marxianus (K. marxianus) is an increasingly popular industrially relevant yeast. It is known to possess a highly efficient...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7111: Injectable Thermo-Sensitive Chitosan Hydrogel Containing CPT-11-Loaded EGFR-Targeted Graphene Oxide and SLP2 shRNA for Localized Drug/Gene Delivery in Glioblastoma Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21197111 Authors: Yu-Jen Lu Yu-Hsiang Lan Chi-Cheng Chuang Wan-Ting Lu Li-Yang Chan Peng-Wei Hsu Jyh-Ping Chen In this study, we aimed to develop a multifunctional drug/gene delivery system for the treatment of...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7113: Patient-Derived Induced Pluripotent Stem Cell-Based Models in Parkinson’s Disease for Drug Identification International Journal of Molecular Sciences doi: 10.3390/ijms21197113 Authors: Kouroupi Antoniou Prodromidou Taoufik Matsas Parkinson’s disease (PD) is a common progressive neurodegenerative disorder characterized by loss of striatal-projecting dopaminergic neurons of the ventral forebrain, resulting in motor and cognitive deficits....
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7110: Characterization of Fecal Microbiota with Clinical Specimen Using Long-Read and Short-Read Sequencing Platform International Journal of Molecular Sciences doi: 10.3390/ijms21197110 Authors: Po-Li Wei Ching-Sheng Hung Yi-Wei Kao Ying-Chin Lin Cheng-Yang Lee Tzu-Hao Chang Ben-Chang Shia Jung-Chun Lin Accurate and rapid identification of microbiotic communities using 16S ribosomal (r)RNA sequencing is a critical task for expanding medical...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7107: Effects of Diabetes Mellitus on Fibrin Clot Structure and Mechanics in a Model of Acute Neutrophil Extracellular Traps (NETs) Formation International Journal of Molecular Sciences doi: 10.3390/ijms21197107 Authors: Judith J. de Vries Tamara Hoppenbrouwers Cristina Martinez-Torres Rezin Majied Behiye Özcan Mandy van Hoek Frank W.G. Leebeek Dingeman C. Rijken Gijsje H. Koenderink Moniek P.M. de Maat Subjects with diabetes mellitus (DM)...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7108: RET Receptor Tyrosine Kinase: Role in Neurodegeneration, Obesity, and Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21197108 Authors: Arun Kumar Mahato Yulia A. Sidorova Rearranged during transfection (RET) is the tyrosine kinase receptor that under normal circumstances interacts with ligand at the cell surface and mediates various essential roles in a variety of cellular processes such as proliferation, differentiation, survival, migration,...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7109: Primary Cilia and Calcium Signaling Interactions International Journal of Molecular Sciences doi: 10.3390/ijms21197109 Authors: Hannah Saternos Sidney Ley Wissam AbouAlaiwi The calcium ion (Ca2+) is a diverse secondary messenger with a near-ubiquitous role in a vast array of cellular processes. Cilia are present on nearly every cell type in either a motile or non-motile form; motile cilia generate fluid flow needed for a variety of biological processes,...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7106: Antibacterial Activity of Selected Essential Oil Compounds Alone and in Combination with β-Lactam Antibiotics Against MRSA Strains International Journal of Molecular Sciences doi: 10.3390/ijms21197106 Authors: Paweł Kwiatkowski Łukasz Łopusiewicz Agata Pruss Mateusz Kostek Monika Sienkiewicz Radosław Bonikowski Iwona Wojciechowska-Koszko Barbara Dołęgowska This study aimed to determine the effect of selected essential oil compounds (EOCs)...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7105: Histone Deacetylase Inhibitor SAHA Improves High Salinity Tolerance Associated with Hyperacetylation-Enhancing Expression of Ion Homeostasis-Related Genes in Cotton International Journal of Molecular Sciences doi: 10.3390/ijms21197105 Authors: He Hao Zhang Zhang Ji Cheng Lv Sun Hao Miao Histone acetylation plays an important role in regulation of chromatin structure and gene expression in terms of responding to abiotic stresses....
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7104: In Vitro Feasibility Analysis of a New Sutureless Wound-Closure System Based on a Temperature-Regulated Laser and a Transparent Collagen Membrane for Laser Tissue Soldering (LTS) International Journal of Molecular Sciences doi: 10.3390/ijms21197104 Authors: Moritz Alexander Birkelbach Ralf Smeets Imke Fiedler Lan Kluwe Martin Wehner Tilmann Trebst Philip Hartjen For the post-surgical treatment of oral wounds and mucosal defects beyond a certain...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7102: Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction International Journal of Molecular Sciences doi: 10.3390/ijms21197102 Authors: Fabian Mayr Gabriele Möller Ulrike Garscha Jana Fischer Patricia Rodríguez Castaño Silvia G. Inderbinen Veronika Temml Birgit Waltenberger Stefan Schwaiger Rolf W. Hartmann Christian Gege Stefan Martens Alex Odermatt Amit V. Pandey Oliver Werz Jerzy...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7103: Spectroscopic Properties of Two 5′-(4-Dimethylamino)Azobenzene Conjugated G-Quadruplex Forming Oligonucleotides International Journal of Molecular Sciences doi: 10.3390/ijms21197103 Authors: Concetta Imperatore Antonio Varriale Elisa Rivieccio Angela Pennacchio Maria Staiano Sabato D’Auria Marcello Casertano Carlo Altucci Mohammadhassan Valadan Manjot Singh Marialuisa Menna Michela Varra The synthesis of two 5′-end...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7101: Transcriptomic Profiling for the Autophagy Pathway in Colorectal Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21197101 Authors: Justyna Gil Paweł Karpiński Maria M. Sąsiadek The role of autophagy in colorectal cancer (CRC) pathogenesis appears to be crucial. Autophagy acts both as a tumor suppressor, by removing redundant cellular material, and a tumor-promoting factor, by providing access to components necessary for growth, metabolism,...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7099: Super-Resolution Live Cell Microscopy of Membrane-Proximal Fluorophores International Journal of Molecular Sciences doi: 10.3390/ijms21197099 Authors: Verena Richter Peter Lanzerstorfer Julian Weghuber Herbert Schneckenburger Here, we present a simple and robust experimental setup for the super-resolution live cell microscopy of membrane-proximal fluorophores, which is comparably easy to perform and to implement. The method is based on Structured Illumination...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7100: Blocking IL-17: A Promising Strategy in the Treatment of Systemic Rheumatic Diseases International Journal of Molecular Sciences doi: 10.3390/ijms21197100 Authors: Carlos Rafael-Vidal Nair Pérez Irene Altabás Samuel Garcia Jose M. Pego-Reigosa Systemic rheumatic diseases are a heterogeneous group of autoimmune disorders that affect the connective tissue, characterized by the involvement of multiple organs, leading to disability, organ failure and...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7098: Inhibition of Angiogenesis by Treatment with Cold Atmospheric Plasma as a Promising Therapeutic Approach in Oncology International Journal of Molecular Sciences doi: 10.3390/ijms21197098 Authors: Lyubomir Haralambiev Ole Neuffer Andreas Nitsch Nele C. Kross Sander Bekeschus Peter Hinz Alexander Mustea Axel Ekkernkamp Denis Gümbel Matthias B. Stope Background: Cold atmospheric plasma (CAP) is increasingly used in the field of oncology....
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7097: Prolonged Lipid Accumulation in Cultured Primary Human Hepatocytes Rather Leads to ER Stress than Oxidative Stress International Journal of Molecular Sciences doi: 10.3390/ijms21197097 Authors: Christiane Rennert Theresa Heil Gerda Schicht Anna Stilkerich Lena Seidemann Victoria Kegel-Hübner Daniel Seehofer Georg Damm Overweight has become a major health care problem in Western societies and is accompanied by an increasing incidence and...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7096: The Role and Impact of Extracellular Vesicles in the Modulation and Delivery of Cytokines during Autoimmunity International Journal of Molecular Sciences doi: 10.3390/ijms21197096 Authors: Mohammed Tayab Hussain Asif Jilani Iqbal Lucy Victoria Norling Cytokines and extracellular vesicles are two methods of initiating and maintaining cellular crosstalk. The role of cytokines in the initiation, progression, and resolution of inflammation has been well studied...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7095: MOS1 Negatively Regulates Sugar Responses and Anthocyanin Biosynthesis in Arabidopsis International Journal of Molecular Sciences doi: 10.3390/ijms21197095 Authors: Ning Zhang Maike Wang Jie Huang Leiyun Yang Zhixue Wang Dianxing Wu Xiaoli Shu Sugars, which are important signaling molecules, regulate diverse biological processes in plants. However, the convergent regulatory mechanisms governing these physiological activities have not been...
Sat Sep 26, 2020 03:00
IJMS, Vol. 21, Pages 7094: Sub-Nanometer Cryo-EM Density Map of the Human Heterodimeric Amino Acid Transporter 4F2hc-LAT2 International Journal of Molecular Sciences doi: 10.3390/ijms21197094 Authors: Jean-Marc Jeckelmann Dimitrios Fotiadis Heterodimeric amino acid transporters (HATs) are protein complexes mediating the transport of amino acids and derivatives thereof across biological membranes. HATs are composed of two subunits, a heavy and a light chain subunit belonging to the...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7093: The Role of microRNAs in Epithelial Ovarian Cancer Metastasis International Journal of Molecular Sciences doi: 10.3390/ijms21197093 Authors: Vu Hong Loan Nguyen Chenyang Yue Kevin Y. Du Mohamed Salem Jacob O'Brien Chun Peng Epithelial ovarian cancer (EOC) is the deadliest gynecological cancer, and the major cause of death is mainly attributed to metastasis. MicroRNAs (miRNAs) are a group of small non-coding RNAs that exert important regulatory...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7066: PAI-1, the Plasminogen System, and Skeletal Muscle International Journal of Molecular Sciences doi: 10.3390/ijms21197066 Authors: Fasih Ahmad Rahman Matthew Paul Krause The plasminogen system is a critical proteolytic system responsible for the remodeling of the extracellular matrix (ECM). The master regulator of the plasminogen system, plasminogen activator inhibitor-1 (PAI-1), has been implicated for its role in exacerbating various disease states not...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7091: Intramolecular Spodium Bonds in Zn(II) Complexes: Insights from Theory and Experiment International Journal of Molecular Sciences doi: 10.3390/ijms21197091 Authors: Mainak Karmakar Antonio Frontera Shouvik Chattopadhyay Tiddo J. Mooibroek Antonio Bauzá Two new dinuclear zinc(II) complexes, [Zn2(µ1,3-OAc)(L1)2]I·MeOH (1) and [Zn2(µ1,3-OAc)(L2)(NCS)] (2), (where HL1 = 2-(((3-(dimethylamino)propyl)amino)methyl)-6-methoxy-phenol...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7090: Role of SARS-CoV-2 in Altering the RNA-Binding Protein and miRNA-Directed Post-Transcriptional Regulatory Networks in Humans International Journal of Molecular Sciences doi: 10.3390/ijms21197090 Authors: Rajneesh Srivastava Swapna Vidhur Daulatabad Mansi Srivastava Sarath Chandra Janga The outbreak of a novel coronavirus SARS-CoV-2 responsible for the COVID-19 pandemic has caused a worldwide public health emergency. Due to the constantly evolving nature...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7092: Pressure Stimuli Improve the Proliferation of Wharton’s Jelly-Derived Mesenchymal Stem Cells under Hypoxic Culture Conditions International Journal of Molecular Sciences doi: 10.3390/ijms21197092 Authors: Sang Eon Park Hyeongseop Kim Soojin Kwon Suk-joo Choi Soo-young Oh Gyu Ha Ryu Hong Bae Jeon Jong Wook Chang Mesenchymal stem cells (MSCs) are safe, and they have good therapeutic efficacy through their paracrine action. However, long-term...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7088: Chaperone Sigma1R and Antidepressant Effect International Journal of Molecular Sciences doi: 10.3390/ijms21197088 Authors: Mikhail V. Voronin Yulia V. Vakhitova Sergei B. Seredenin This review analyzes the current scientific literature on the role of the Sigma1R chaperone in the pathogenesis of depressive disorders and pharmacodynamics of antidepressants. As a result of ligand activation, Sigma1R is capable of intracellular translocation from the endoplasmic...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7089: Remodeling the Skeletal Muscle Extracellular Matrix in Older Age—Effects of Acute Exercise Stimuli on Gene Expression International Journal of Molecular Sciences doi: 10.3390/ijms21197089 Authors: Matthias Gumpenberger Barbara Wessner Alexandra Graf Marco V. Narici Christian Fink Sepp Braun Christian Hoser Anthony J. Blazevich Robert Csapo With advancing age, the skeletal muscle extracellular matrix (ECM) undergoes fibrotic changes that...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7067: In Vitro Maturation with Leukemia Inhibitory Factor Prior to the Vitrification of Bovine Oocytes Improves Their Embryo Developmental Potential and Gene Expression in Oocytes and Embryos International Journal of Molecular Sciences doi: 10.3390/ijms21197067 Authors: Meritxell Vendrell-Flotats Tania García-Martínez Iris Martínez-Rodero Manel Lopez-Bejar Jonathan LaMarre Marc Yeste Teresa Mogas Oocyte cryopreservation has a significant impact...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7087: Development of Heterocycle-Substituted and Fused Azulenes in the Last Decade (2010–2020) International Journal of Molecular Sciences doi: 10.3390/ijms21197087 Authors: Taku Shoji Tetsuo Okujima Shunji Ito Azulene derivatives with heterocyclic moieties in the molecule have been synthesized for applications in materials science by taking advantage of their unique properties. These derivatives have been prepared by various methods, involving electrophilic...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7085: Protective Effect of CXCR4 Antagonist CX807 in a Rat Model of Hemorrhagic Stroke International Journal of Molecular Sciences doi: 10.3390/ijms21197085 Authors: Seong-Jin Yu Kuo-Jen Wu Yu-Syuan Wang Jen-Shin Song Chien-Huang Wu Jiing-Jyh Jan Eunkyung Bae Hsi Chen Kak-Shan Shia Yun Wang Intracerebral hemorrhage (ICH) is a major cause of stroke, with high mortality and morbidity. There is no effective pharmacological therapy for ICH....
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7073: Efficient Delivery and Replication of Oncolytic Virus for Successful Treatment of Head and Neck Cancer International Journal of Molecular Sciences doi: 10.3390/ijms21197073 Authors: Masakazu Hamada Yoshiaki Yura Head and neck cancer has been treated by a combination of surgery, radiation, and chemotherapy. In recent years, the development of immune checkpoint inhibitors (ICIs) has made immunotherapy a new treatment method. Oncolytic virus (OV) therapy selectively...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7084: A Review of the Action of Magnesium on Several Processes Involved in the Modulation of Hematopoiesis International Journal of Molecular Sciences doi: 10.3390/ijms21197084 Authors: Fabiana da Silva Lima Ricardo Ambrósio Fock Magnesium (Mg2+) is an essential mineral for the functioning and maintenance of the body. Disturbances in Mg2+ intracellular homeostasis result in cell-membrane modification, an increase in oxidative stress, alteration in the proliferation...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7086: Transcriptome-Wide Analysis of Interplay between mRNA Stability, Translation and Small RNAs in Response to Neuronal Membrane Depolarization International Journal of Molecular Sciences doi: 10.3390/ijms21197086 Authors: Dylan J. Kiltschewskij Murray J. Cairns Experience-dependent changes to neural circuitry are shaped by spatially-restricted activity-dependent mRNA translation. Although the complexity of mRNA translation in neuronal cells is widely appreciated,...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7076: YB-1 Interferes with TNFα–TNFR Binding and Modulates Progranulin-Mediated Inhibition of TNFα Signaling International Journal of Molecular Sciences doi: 10.3390/ijms21197076 Authors: Christopher L. Hessman Josephine Hildebrandt Aneri Shah Sabine Brandt Antonia Bock Björn C. Frye Ute Raffetseder Robert Geffers Monika C. Brunner-Weinzierl Berend Isermann Peter R. Mertens Jonathan A. Lindquist Inflammation and an influx of macrophages...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7082: Silver Nanoparticles Protect Skin from Ultraviolet B-Induced Damage in Mice International Journal of Molecular Sciences doi: 10.3390/ijms21197082 Authors: Yu-Yi Ho Der-Shan Sun Hsin-Hou Chang Ultraviolet (UV) radiation from sunlight has various adverse effects; thus, UV blockage is recommended for preventing sunburn. Common sunscreen ingredients, such as nanosized titanium dioxide and zinc oxide, offer effective protection and enhance cosmetic appearance;...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7083: In Situ Gelling Systems Using Pluronic F127 Enhance Corneal Permeability of Indomethacin Nanocrystals International Journal of Molecular Sciences doi: 10.3390/ijms21197083 Authors: Noriaki Nagai Takumi Isaka Saori Deguchi Misa Minami Mizuki Yamaguchi Hiroko Otake Norio Okamoto Yosuke Nakazawa We previously designed an ophthalmic dispersion containing indomethacin nanocrystals (IMC-NCs), showing that multiple energy-dependent endocytoses...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7081: Impact of HLA-DR Antigen Binding Cleft Rigidity on T Cell Recognition International Journal of Molecular Sciences doi: 10.3390/ijms21197081 Authors: Christopher Szeto Joseph I. Bloom Hannah Sloane Christian A. Lobos James Fodor Dhilshan Jayasinghe Demetra S. M. Chatzileontiadou Emma J. Grant Ashley M. Buckle Stephanie Gras The interaction between T cell receptor (TCR) and peptide (p)-Human Leukocyte Antigen (HLA) complexes is the...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7078: Monoterpenes and Their Derivatives—Recent Development in Biological and Medical Applications International Journal of Molecular Sciences doi: 10.3390/ijms21197078 Authors: Mariola Zielińska-Błajet Joanna Feder-Kubis Monoterpenes, comprising hydrocarbons, are the largest class of plant secondary metabolites and are commonly found in essential oils. Monoterpenes and their derivatives are key ingredients in the design and production of new biologically active...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7080: Epigenetic Regulators Involved in Osteoclast Differentiation International Journal of Molecular Sciences doi: 10.3390/ijms21197080 Authors: Kristina Astleford Emily Campbell Andrew Norton Kim C. Mansky Age related changes to the skeleton, such as osteoporosis, increase the risk of fracture and morbidity in the elderly population. In osteoporosis, bone remodeling becomes unbalanced with an increase in bone resorption and a decrease in bone formation....
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7072: Electroconvulsive Shock Does Not Impair the Reconsolidation of Cued and Contextual Pavlovian Threat Memory International Journal of Molecular Sciences doi: 10.3390/ijms21197072 Authors: Hajira Elahi Veronica Hong Jonathan E. Ploski Existing memories, when retrieved under certain circumstances, can undergo modification through the protein synthesis-dependent process of reconsolidation. Disruption of this process can lead to the weakening of a memory trace,...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7077: Cannabidiol Ameliorates Monocrotaline-Induced Pulmonary Hypertension in Rats International Journal of Molecular Sciences doi: 10.3390/ijms21197077 Authors: Olga Sadowska Marta Baranowska-Kuczko Anna Gromotowicz-Popławska Michał Biernacki Aleksandra Kicman Barbara Malinowska Irena Kasacka Anna Krzyżewska Hanna Kozłowska Cannabidiol (CBD) is known for its vasorelaxant (including in the human pulmonary artery), anti-proliferative and anti-inflammatory...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7069: Human Fibroblasts In Vitro Exposed to 2.45 GHz Continuous and Pulsed Wave Signals: Evaluation of Biological Effects with a Multimethodological Approach International Journal of Molecular Sciences doi: 10.3390/ijms21197069 Authors: Elisa Regalbuto Anna Anselmo Stefania De Sanctis Valeria Franchini Florigio Lista Monica Benvenuto Roberto Bei Laura Masuelli Guglielmo D’Inzeo Alessandra Paffi Eugenio Trodella Antonella Sgura The...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7079: Alternative Splicing Regulation of an Alzheimer’s Risk Variant in CLU International Journal of Molecular Sciences doi: 10.3390/ijms21197079 Authors: Seonggyun Han Kwangsik Nho Younghee Lee Clusterin (CLU) is one of the risk genes most associated with late onset Alzheimer’s disease (AD), and several genetic variants in CLU are associated with AD risk. However, the functional role of known AD risk genetic variants in CLU has been little explored....
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7057: New Insights into the Mechanisms of Pyroptosis and Implications for Diabetic Kidney Disease International Journal of Molecular Sciences doi: 10.3390/ijms21197057 Authors: Jinwen Lin Ao Cheng Kai Cheng Qingwei Deng Shouzan Zhang Zehao Lan Weidong Wang Jianghua Chen Pyroptosis is one special type of lytic programmed cell death, featured in cell swelling, rupture, secretion of cell contents and remarkable proinflammation effect. In the process...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7074: A Simple and Efficient Genetic Immunization Protocol for the Production of Highly Specific Polyclonal and Monoclonal Antibodies against the Native Form of Mammalian Proteins International Journal of Molecular Sciences doi: 10.3390/ijms21197074 Authors: Julie Pelletier Hervé Agonsanou Fabiana Manica Elise G. Lavoie Mabrouka Salem Patrick Luyindula Romuald Brice Babou Kammoe Jean Sévigny We have generated polyclonal and monoclonal antibodies...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7075: Constitutive Activation and Inactivation of Mutations Inducing Cell Surface Loss of Receptor and Impairing of Signal Transduction of Agonist-Stimulated Eel Follicle-Stimulating Hormone Receptor International Journal of Molecular Sciences doi: 10.3390/ijms21197075 Authors: Munkhzaya Byambaragchaa Jeong-Soo Kim Hong-Kyu Park Dae-Jung Kim Sun-Mee Hong Myung-Hwa Kang Kwan-Sik Min In the present study, we investigated the signal transduction of...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7068: Induced Short-Term Hearing Loss due to Stimulation of Age-Related Factors by Intermittent Hypoxia, High-Fat Diet, and Galactose Injection International Journal of Molecular Sciences doi: 10.3390/ijms21197068 Authors: Dong Jun Park Sunmok Ha Jin Sil Choi Su Hoon Lee Jeong-Eun Park Young Joon Seo Age-related hearing loss (ARHL) is the most common sensory disorder among the elderly, associated with aging and auditory hair cell death due to oxidative-stress-induced...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7071: Differential Production of Cartilage ECM in 3D Agarose Constructs by Equine Articular Cartilage Progenitor Cells and Mesenchymal Stromal Cells International Journal of Molecular Sciences doi: 10.3390/ijms21197071 Authors: Stefanie Schmidt Florencia Abinzano Anneloes Mensinga Jörg Teßmar Jürgen Groll Jos Malda Riccardo Levato Torsten Blunk Identification of articular cartilage progenitor cells (ACPCs) has opened up new opportunities for...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7070: Atraric Acid Exhibits Anti-Inflammatory Effect in Lipopolysaccharide-Stimulated RAW264.7 Cells and Mouse Models International Journal of Molecular Sciences doi: 10.3390/ijms21197070 Authors: Seul-Ki Mun Kyung-Yun Kang Ho-Yeol Jang Yun-Ho Hwang Seong-Gyeol Hong Su-Jin Kim Hyun-Wook Cho Dong-Jo Chang Jae-Seoun Hur Sung-Tae Yee Lichens, composite organisms resulting from the symbiotic association between the fungi and algae, produce...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7064: Biphasic Force-Regulated Phosphorylation Site Exposure and Unligation of ERM Bound with PSGL-1: A Novel Insight into PSGL-1 Signaling via Steered Molecular Dynamics Simulations International Journal of Molecular Sciences doi: 10.3390/ijms21197064 Authors: Jingjing Feng Yan Zhang Quhuan Li Ying Fang Jianhua Wu The PSGL-1-actin cytoskeleton linker proteins ezrin/radixin/moesin (ERM), an adaptor between P-selectin glycoprotein ligand-1 (PSGL-1) and...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7065: Identification of Acute Myeloid Leukemia Bone Marrow Circulating MicroRNAs International Journal of Molecular Sciences doi: 10.3390/ijms21197065 Authors: Douâa Moussa Agha Redouane Rouas Mehdi Najar Fatima Bouhtit Najib Naamane Hussein Fayyad-Kazan Dominique Bron Nathalie Meuleman Philippe Lewalle Makram Merimi Background: In addition to their roles in different biological processes, microRNAs in the tumor microenvironment appear...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7063: Functional Recovery of a GCDH Variant Associated to Severe Deflavinylation—Molecular Insights into Potential Beneficial Effects of Riboflavin Supplementation in Glutaric Aciduria-Type I Patients International Journal of Molecular Sciences doi: 10.3390/ijms21197063 Authors: Joana V. Ribeiro Cláudio M. Gomes Bárbara J. Henriques Riboflavin is the biological precursor of two important flavin cofactors—flavin adenine dinucleotide (FAD) and flavin...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7062: PKM2 Determines Myofiber Hypertrophy In Vitro and Increases in Response to Resistance Exercise in Human Skeletal Muscle International Journal of Molecular Sciences doi: 10.3390/ijms21197062 Authors: Sander A. J. Verbrugge Sebastian Gehlert Lian E. M. Stadhouders Daniel Jacko Thorben Aussieker Gerard M. J. de Wit Ilse S. P. Vogel Carla Offringa Martin Schönfelder Richard T. Jaspers Henning Wackerhage Nearly 100 years ago, Otto Warburg...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7060: Aging-Related Disorders and Mitochondrial Dysfunction: A Critical Review for Prospect Mitoprotective Strategies Based on Mitochondrial Nutrient Mixtures International Journal of Molecular Sciences doi: 10.3390/ijms21197060 Authors: Giovanni Pagano Federico V. Pallardó Alex Lyakhovich Luca Tiano Maria Rosa Fittipaldi Maria Toscanesi Marco Trifuoggi A number of aging-related disorders (ARD) have been related to oxidative stress (OS) and mitochondrial...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7061: Staphylococcus aureus Host Tropism and Its Implications for Murine Infection Models International Journal of Molecular Sciences doi: 10.3390/ijms21197061 Authors: Daniel M. Mrochen Liliane M. Fernandes de Oliveira Dina Raafat Silva Holtfreter Staphylococcus aureus (S. aureus) is a pathobiont of humans as well as a multitude of animal species. The high prevalence of multi-resistant and more virulent strains of S. aureus necessitates the development...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7058: Cellular Prion Protein (PrPc): Putative Interacting Partners and Consequences of the Interaction International Journal of Molecular Sciences doi: 10.3390/ijms21197058 Authors: Hajar Miranzadeh Mahabadi Changiz Taghibiglou Cellular prion protein (PrPc) is a small glycosylphosphatidylinositol (GPI) anchored protein most abundantly found in the outer leaflet of the plasma membrane (PM) in the central nervous system (CNS). PrPc misfolding causes neurodegenerative...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7059: STING-Mediated Autophagy Is Protective against H2O2-Induced Cell Death International Journal of Molecular Sciences doi: 10.3390/ijms21197059 Authors: Amar Abdullah Frank Mobilio Peter J. Crack Juliet M. Taylor Stimulator of interferon genes (STING)-mediated type-I interferon signaling is a well characterized instigator of the innate immune response following bacterial or viral infections in the periphery. Emerging evidence has recently linked STING...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7055: Exosomes: Insights from Retinoblastoma and Other Eye Cancers International Journal of Molecular Sciences doi: 10.3390/ijms21197055 Authors: Kashmiri Lande Jitesh Gupta Ravi Ranjan Manjari Kiran Luis Fernando Torres Solis Arturo Solís Herrera Gjumrakch Aliev Roy Karnati Exosomes, considered as cell debris or garbage bags, have been later characterized as nanometer-sized extracellular double-membrane lipid bilayer bio-vesicles secreted by...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7056: Multi-Compartment, Early Disruption of cGMP and cAMP Signalling in Cardiac Myocytes from the mdx Model of Duchenne Muscular Dystrophy International Journal of Molecular Sciences doi: 10.3390/ijms21197056 Authors: Marcella Brescia Ying-Chi Chao Andreas Koschinski Jakub Tomek Manuela Zaccolo Duchenne muscular dystrophy (DMD) is the most frequent and severe form of muscular dystrophy. The disease presents with progressive body-wide muscle deterioration...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7053: The Molecular Mechanisms of Adaptive Response Related to Environmental Stress International Journal of Molecular Sciences doi: 10.3390/ijms21197053 Authors: Andrea Rossnerova Alberto Izzotti Alessandra Pulliero Aalt Bast S. I. S. Rattan Pavel Rossner The exposure of living organisms to environmental stress triggers defensive responses resulting in the activation of protective processes. Whenever the exposure occurs at low doses, defensive effects...
Fri Sep 25, 2020 03:00
IJMS, Vol. 21, Pages 7054: In Search of New Therapeutics—Molecular Aspects of the PCOS Pathophysiology: Genetics, Hormones, Metabolism and Beyond International Journal of Molecular Sciences doi: 10.3390/ijms21197054 Authors: Agata Wawrzkiewicz-Jałowiecka Karolina Kowalczyk Paulina Trybek Tomasz Jarosz Patrycja Radosz Marcin Setlak Paweł Madej In a healthy female reproductive system, a subtle hormonal and metabolic dance leads to repetitive cyclic changes in the ovaries...
Fri Sep 25, 2020 03:00
IJNS, Vol. 6, Pages 76: We All Have a Role to Play: Redressing Inequities for Children Living with CAH and Other Chronic Health Conditions of Childhood in Resource-Poor Settings International Journal of Neonatal Screening doi: 10.3390/ijns6040076 Authors: Kate Armstrong Alain Benedict Yap Sioksoan Chan-Cua Maria E. Craig Catherine Cole Vu Chi Dung Joseph Hansen Mohsina Ibrahim Hassana Nadeem Aman Pulungan Jamal Raza Agustini Utari Paul Ward CLAN (Caring...
Fri Sep 25, 2020 03:00
JCDD, Vol. 7, Pages 39: Left Ventricular Noncompaction Is More Prevalent in Ventricular Septal Defect Than Other Congenital Heart Defects: A Morphological Study Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd7040039 Authors: Laís Costa Marques Gabriel Romero Liguori Ana Carolina Amarante Amarante Souza Vera Demarchi Aiello Left ventricular noncompaction (LVNC) is a condition characterized by prominent ventricular trabeculae and deep intertrabecular recesses...
Fri Sep 25, 2020 03:00
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