Related Articles Progression of Fetal Brain Lesions in Tuberous Sclerosis Complex. Front Neurosci. 2020;14:899 Authors: Gelot AB, Represa A Abstract Tuberous sclerosis (TSC) is a multisystem autosomal dominant genetic disorder due to loss of function of TSC1/TSC2 resulting in increased mTOR (mammalian target of rapamycin) signaling. In the brain, TSC is characterized by the formation of specific lesions that include subependymal and white matter...
Sat Sep 26, 2020 13:38
Related Articles Remote Microphone Hearing Aid Use Improves Classroom Listening, Without Adverse Effects on Spatial Listening and Attention Skills, in Children With Auditory Processing Disorder: A Randomised Controlled Trial. Front Neurosci. 2020;14:904 Authors: Stavrinos G, Iliadou VV, Pavlou M, Bamiou DE Abstract Background: Children with Auditory Processing Disorder (APD) often have poor auditory processing skills in the presence of normal...
Sat Sep 26, 2020 13:38
Related Articles The influence of stimulation levels on auditory thresholds and speech recognition in adult cochlear implant users. Cochlear Implants Int. 2020 Sep 24;:1-7 Authors: Martins KVC, Goffi-Gomez MVS Abstract Objective: This study aims to evaluate the influence of minimum and maximum stimulation levels on auditory thresholds and speech recognition abilities in adult cochlear implant users. Method: Fifteen adults implanted with...
Sat Sep 26, 2020 13:40
Related Articles Spinal cord injury in the United States Army Special Forces. J Neurosurg Spine. 2020 Sep 25;:1-7 Authors: Kessler RA, Bhammar A, Lakomkin N, Shrivastava RK, Rasouli JJ, Steinberger J, Bederson J, Hadjipanayis CG, Benzil DL Abstract OBJECTIVE: Spinal cord injury (SCI) is an area of key interest in military medicine but has not been studied among the US Army Special Forces (SF), the most elite group of US soldiers. SF soldiers...
Sat Sep 26, 2020 13:42
Authors: Arwa Lachkhem, Ibtissem Lahmar, Lokman Galal, Oussama Babba, Habib Mezhoud, Mohssen Hassine, Ahmed Lachkhem, Marie-Laure Dardé, Aurélien Mercier and Hamouda Babba.Parasite Vol. 27 , page 51Published online: 21/09/2020 Keywords: Toxoplasma gondii ; Blood donors ; Seroprevalence ; Risk factors ; Tunisia.
Mon Sep 21, 2020 03:00
Related Articles General Distributed Neural Control and Sensory Adaptation for Self-Organized Locomotion and Fast Adaptation to Damage of Walking Robots. Front Neural Circuits. 2020;14:46 Authors: Miguel-Blanco A, Manoonpong P Abstract Walking animals such as invertebrates can effectively perform self-organized and robust locomotion. They can also quickly adapt their gait to deal with injury or damage. Such a complex achievement is mainly performed...
Sat Sep 26, 2020 13:45
Related Articles Monochromatic Blue Light Activates Suprachiasmatic Nucleus Neuronal Activity and Promotes Arousal in Mice Under Sevoflurane Anesthesia. Front Neural Circuits. 2020;14:55 Authors: Liu D, Li J, Wu J, Dai J, Chen X, Huang Y, Zhang S, Tian B, Mei W Abstract Background: Monochromatic blue light (MBL), with a wavelength between 400-490 nm, can regulate non-image-forming (NIF) functions of light in the central nervous system. The suprachiasmatic...
Sat Sep 26, 2020 13:45
303 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/09/26PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Sep 26, 2020 13:51
Related Articles Commentary 1: Introduction: At the Crossroads of Chronic Overlapping Pain Conditions and Research Diagnostic Criteria: Which Direction to Take? J Oral Facial Pain Headache. 2020 Suppl;34:s3-s5 Authors: LeResche L, Von Korff M PMID: 32975533 [PubMed - as supplied by publisher]
Sat Sep 26, 2020 13:56
Related Articles Commentary 2: Further Evidence for Overlaps Among Chronic Pain Conditions-But No News About Causal Relationships. J Oral Facial Pain Headache. 2020 Suppl;34:s6-s8 Authors: Svensson P, Exposto F PMID: 32975534 [PubMed - as supplied by publisher]
Sat Sep 26, 2020 13:56
Related Articles Commentary 3: Temporomandibular Disorders- Casting the Net to Find Answers. J Oral Facial Pain Headache. 2020 Suppl;34:s9-s10 Authors: Stohler CS PMID: 32975535 [PubMed - as supplied by publisher]
Sat Sep 26, 2020 13:56
Related Articles Commentary 4: OPPERA-2 Conundrums and Challenges: Lumping Versus Splitting? J Oral Facial Pain Headache. 2020 Suppl;34:s11 Authors: Benoliel R PMID: 32975536 [PubMed - as supplied by publisher]
Sat Sep 26, 2020 13:56
Related Articles Authors' Response: When You Come to the Fork in the Road, Take It! Future Research into Chronic Pain as a General Condition. J Oral Facial Pain Headache. 2020 Suppl;34:s12-s14 Authors: Ohrbach R, Fillingim RB, Greenspan JD, Maixner W, Sanders AE, Sharma S, Slade GD PMID: 32975537 [PubMed - as supplied by publisher]
Sat Sep 26, 2020 13:56
Related Articles Overlap of Five Chronic Pain Conditions: Temporomandibular Disorders, Headache, Back Pain, Irritable Bowel Syndrome, and Fibromyalgia. J Oral Facial Pain Headache. 2020 Suppl;34:s15-s28 Authors: Slade GD, Greenspan JD, Fillingim RB, Maixner W, Sharma S, Ohrbach R Abstract AIMS: To assess cohort retention in the OPPERA project and to compare the degree of overlap between pairs of chronic overlapping pain conditions (COPCs)...
Sat Sep 26, 2020 13:56
Related Articles Clinical Characteristics of Pain Among Five Chronic Overlapping Pain Conditions. J Oral Facial Pain Headache. 2020 Suppl;34:s29-s42 Authors: Ohrbach R, Sharma S, Fillingim RB, Greenspan JD, Rosen JD, Slade GD Abstract AIMS: To describe the pain characteristics of five index chronic overlapping pain conditions (COPCs) and to assess each COPC separately in order to determine whether the presence of comorbid COPCs is associated...
Sat Sep 26, 2020 13:56
Related Articles Experimental Pain Sensitivity in Subjects with Temporomandibular Disorders and Multiple Other Chronic Pain Conditions: The OPPERA Prospective Cohort Study. J Oral Facial Pain Headache. 2020 Suppl;34:s43-s56 Authors: Greenspan JD, Slade GD, Rathnayaka N, Fillingim RB, Ohrbach R, Maixner W Abstract AIMS: To investigate associations between experimental pain sensitivity and five chronic pain conditions among 655 participants...
Sat Sep 26, 2020 13:56
Related Articles Attributes Germane to Temporomandibular Disorders and Their Associations with Five Chronic Overlapping Pain Conditions. J Oral Facial Pain Headache. 2020 Suppl;34:s57-s72 Authors: Sharma S, Slade GD, Fillingim RB, Greenspan JD, Rathnayaka N, Ohrbach R Abstract AIMS: To investigate whether TMD-related characteristics are indeed specific to TMD or whether they are also associated with other chronic overlapping pain conditions...
Sat Sep 26, 2020 13:56
Related Articles Associations of Sleep Disturbance, Atopy, and Other Health Measures with Chronic Overlapping Pain Conditions. J Oral Facial Pain Headache. 2020 Suppl;34:s73-s84 Authors: Sanders AE, Greenspan JD, Fillingim RB, Rathnayaka N, Ohrbach R, Slade GD Abstract AIMS: To quantify the contributions of atopic disorders, sleep disturbance, and other health conditions to five common pain conditions. METHODS: This cross-sectional...
Sat Sep 26, 2020 13:56
Related Articles Associations of Psychologic Factors with Multiple Chronic Overlapping Pain Conditions. J Oral Facial Pain Headache. 2020 Suppl;34:s85-s100 Authors: Fillingim RB, Ohrbach R, Greenspan JD, Sanders AE, Rathnayaka N, Maixner W, Slade GD Abstract AIMS: To characterize psychologic functioning across five chronic overlapping pain conditions (COPCs)-temporomandibular disorders, fibromyalgia, low back pain, headache, and irritable...
Sat Sep 26, 2020 13:56
Publication date: 15 January 2021Source: Talanta, Volume 222Author(s): Lei Huang, Shulin Tian, Wenhao Zhao, Ke Liu, Jinhong Guo
Sat Sep 26, 2020 14:06
Publication date: 15 January 2021Source: Talanta, Volume 222Author(s): L.S. Castillo-Peinado, M. Calderón-Santiago, F. Priego-Capote
Sat Sep 26, 2020 14:06
Publication date: 15 January 2021Source: Talanta, Volume 222Author(s): Jing He, Wenxin Wang, Hong Zhang, Yun Ju, Kai Yu, Xiangnan Zhang, Jie Jiang
Sat Sep 26, 2020 14:06
Publication date: 15 January 2021Source: Talanta, Volume 222Author(s): Lidia Akemi Akamine, Deyber Arley Vargas Medina, Fernando Mauro Lanças
Sat Sep 26, 2020 14:06
Publication date: 15 January 2021Source: Talanta, Volume 222Author(s): Ruipeng Chen, Yunfeng Sun, Bingyang Huo, Xudong Zhao, Hui Huang, Shuang Li, Jialei Bai, Jun Liang, Zhixian Gao
Sat Sep 26, 2020 14:06
Publication date: 15 January 2021Source: Talanta, Volume 222Author(s): Adam Sajnóg, Marcin Tkaczyk, Małgorzata Stańczyk, Krzysztof Szaflik, Joanna Suliburska, Rafał Kocyłowski, Danuta Barałkiewicz
Sat Sep 26, 2020 14:06
Publication date: 15 January 2021Source: Talanta, Volume 222Author(s): Seyedeh Maedeh Majidi, Mohammad Reza Hadjmohammadi
Sat Sep 26, 2020 14:06
Publication date: 15 January 2021Source: Talanta, Volume 222Author(s): Yuqi Lu, Feifei Luo, Zhi Li, Ge Dai, Zhaohui Chu, Jingwen Zhang, Fan Zhang, Qingjiang Wang, Pingang He
Sat Sep 26, 2020 14:06
Publication date: 15 January 2021Source: Talanta, Volume 222Author(s): Yinhui Yi, Wei Zeng, Gangbing Zhu
Sat Sep 26, 2020 14:06
Related Articles Predicting difficult-to-treat chronic rhinosinusitis by noninvasive biological markers. Rhinology. 2020 Sep 25;: Authors: Guo CL, Liao B, Liu JX, Pan L, Liu Z Abstract BACKGROUND: Previous studies have been limited to the utility of clinical features and invasive nasal mucosal biomarkers in the prediction of chronic rhinosinusitis (CRS) outcomes. This study aimed to identify noninvasive biomarkers associated with difficult-...
Sat Sep 26, 2020 14:08
The One Stop Prostate Clinic – same‐day assessment and/or prostate cancer diagnostic clinic – was reported in this study. Abstract Background This study reported the outcomes of the first 1000 men to attend the One Stop Prostate Clinic, a consultant‐led same‐day prostate cancer assessment and diagnostic clinic at a tertiary public hospital. Methods Prospective audit of demographic and clinical data between August 2011 and November 2017 was conducted for same‐day urological assessment...
Fri Sep 25, 2020 11:00
Pre‐operative frailty is predictive of adverse post‐operative outcomes in colorectal cancer patients
Perioperative risk assessment in elderly patients is difficult due to physiological heterogeneity in this group, and frailty assessment may be more useful than traditional assessment tools. In this paper, we have shown the presence of frailty to be strongly associated with adverse post‐operative outcomes and to be a stronger predictor than other tools such as American Society of Anesthesiologists physical status classfication. Abstract Background An increasing number of elderly patients...
Fri Sep 25, 2020 11:01
Fri Sep 25, 2020 21:03
Use of validated quality of life questionnaire (ThyPRO) to assess quality of life following benign thyroid surgery in an Australian population. Abstract Background Choosing which patients to recommend surgery for benign thyroid conditions can be difficult due to the subjective nature of compressive thyroid and hormonal symptoms. The aim of this prospective study was to analyse changes in quality of life (QOL) following thyroid surgery using a validated disease‐specific assessment tool,...
Fri Sep 25, 2020 22:54
Related Articles "Does ERAS benefit higher BMI patients? A single institutional review". J Plast Reconstr Aesthet Surg. 2020 Sep 10;: Authors: Shin HD, Rodriguez AM, Abraham JT, Cargile JC, Brown CN, Altman AM, Saint-Cyr MH Abstract BACKGROUND: Enhanced recovery after surgery (ERAS) is increasingly used in plastic surgery to optimize patient care. Mitigating the risk of postoperative complications is particularly important in patients with risk...
Sat Sep 26, 2020 14:13
Related Articles Worse overall health status negatively impacts satisfaction with breast reconstruction. J Plast Reconstr Aesthet Surg. 2020 Sep 11;: Authors: Mehta SK, Olawoyin O, Chouairi F, Duy PQ, Mets EJ, Gabrick KS, Le NK, Avraham T, Alperovich M Abstract BACKGROUND: BREAST-Q is a validated measure of patient satisfaction and health-related quality of life following breast surgery. Limited evidence exists with regard to the influence of...
Sat Sep 26, 2020 14:13
Related Articles Cervical and ocular vestibular evoked myogenic potentials in determining nerve division involvement in patients with a tumor located in the internal auditory canal. Auris Nasus Larynx. 2020 Sep 21;: Authors: Zwierzyńska K, Lachowska M, Sokołowski J, Niemczyk K Abstract OBJECTIVES: The study aimed at the analysis of the parameters of acoustic cervical and ocular vestibular evoked myogenic potentials (AC-cVEMP and AC-oVEMP) response...
Sat Sep 26, 2020 14:16
Abstract Aim Diabetic retinopathy (DR) is a chronic disease causing health and economic burdens on individuals and society. Thus, this study is conducted to figure out the mechanisms of bone marrow mesenchymal stem cells (BMSCs)-induced exosomal microRNA-486-3p (miR-486-3p) in DR. Methods The putative miR-486-3p binding sites to 3′untranslated region...
Sat Sep 26, 2020 03:00
Related Articles Peer Review Week 2020: Eurosurveillance thanks all COVID-19 reviewers for their amazing work. Euro Surveill. 2020 Sep;25(38): Authors: Eurosurveillance editorial team PMID: 32975183 [PubMed - in process]
Sat Sep 26, 2020 14:19
Related Articles Prevention of human rabies: a challenge for the European Union and the European Economic Area. Euro Surveill. 2020 Sep;25(38): Authors: Gossner CM, Mailles A, Aznar I, Dimina E, Echevarría JE, Feruglio SL, Lange H, Maraglino FP, Parodi P, Perevoscikovs J, Van der Stede Y, Bakonyi T Abstract Rabies is enzootic in over one hundred countries worldwide. In the European Union/European Economic Area (EU/EEA), the vast majority of...
Sat Sep 26, 2020 14:19
Related Articles Authors' correction for Euro Surveill. 2020;25(36). Euro Surveill. 2020 Sep;25(38): Authors: Eurosurveillance editorial team PMID: 32975185 [PubMed - in process]
Sat Sep 26, 2020 14:19
Related Articles Surveillance of COVID-19 school outbreaks, Germany, March to August 2020. Euro Surveill. 2020 Sep;25(38): Authors: Otte Im Kampe E, Lehfeld AS, Buda S, Buchholz U, Haas W Abstract Mitigation of the coronavirus disease (COVID-19) pandemic in Germany included school closures in early March 2020. After reopening in April, preventive measures were taken in schools. We analysed national surveillance system data on COVID-19 school...
Sat Sep 26, 2020 14:19
Related Articles Rabies vaccination strategies in the Netherlands in 2018: a cost evaluation. Euro Surveill. 2020 Sep;25(38): Authors: Suijkerbuijk AW, Mangen MJ, Haverkate MR, Luppino FS, Bantjes SE, Visser LG, Swaan CM, Ruijs WL, Over EA Abstract BackgroundThe risk of contracting rabies is low for travellers. However, the number of Dutch travellers potentially exposed abroad following an animal-associated injury and needing post-exposure prophylaxis...
Sat Sep 26, 2020 14:19
Related Articles Abandon of intramuscular administration of rabies immunoglobulin for post-exposure prophylaxis in the revised guidelines in the Netherlands in 2018: cost and volume savings. Euro Surveill. 2020 Sep;25(38): Authors: Schreuder I, De Pijper C, van Kessel R, Visser L, van den Kerkhof H, Dutch advisory committee on rabies Abstract The World Health Organization (WHO) issued an updated position paper on rabies in 2018, mainly focusing...
Sat Sep 26, 2020 14:19
Introduction. The introduction of laryngeal transoral procedures has created a shift in the treatment of laryngeal cancers towards the primary surgical management of patients. In this study, we aimed to evaluate the safety, efficacy, and feasibility of the transoral laser-assisted total laryngectomy (TLM-TL) in advanced laryngeal cancer. Case presentation. In this case report, we describe a case of a 50-year-old male patient presented to the otorhinolaryngology clinic with a history of hoarseness...
Sat Sep 26, 2020 08:35
Abstract Purpose Purinergic P2X7 receptor (P2X7R) is a gated ion channel for which adenosine triphosphate (ATP) is a ligand. Activated P2X7R is widely expressed in a variety of immune cells and tissues and is involved in a variety of physiological and pathological processes. Studies have confirmed that P2X7R is involved in the regulation of tumor cell growth, stimulating cell proliferation or inducing apoptosis. Recent studies...
Sat Sep 26, 2020 14:24
Abstract Background Comorbidity and relative dose intensity (RDI) have been associated with survival in diffuse large B-cell lymphoma (DLBCL) patients, but both relationships remain unaddressed in the same patients. Methods A retrospective review of consecutive DLBCL patients treated from January 2010 to October 2018 was performed. Data...
Sat Sep 26, 2020 14:24
Abstract Purpose The incidence of pancreatic neuroendocrine tumors (pNETs) has continued to increase, but for pNETs, there is still no distinction between treatments based on anatomical location. We aim to determine whether NETs located at the head and body/tail of the pancreas are different. Patients and methods Within the Surveillance,...
Sat Sep 26, 2020 14:24
Abstract Purpose IGF-1Ec is an isoform of Insulin-like growth factor 1 (IGF-1) and has recently been identified to be overexpressed in cancers including prostate and neuroendocrine tumours. The aim of this paper is to investigate the expression of IGF-1Ec in colorectal cancer and polyps compared to normal colon tissues and its association with recurrent disease using semi-quantitative immunohistochemistry. ...
Sat Sep 26, 2020 14:24
Abstract Activation Induced cytidine Deaminase (AID) is an essential enzyme of the adaptive immune system. Its canonical activity is restricted to B lymphocytes, playing an essential role in the diversification of antibodies by enhancing specificity and changing affinity. This is possible through its DNA deaminase function, leading to mutations in DNA. In the last decade, AID has been assigned an additional function: that of a powerful DNA demethylator. Adverse cellular conditions...
Sat Sep 26, 2020 14:24
Abstract Purpose Testicular granulosa cell tumors (tGrCT) are rare sex cord-stromal tumors. This review aims to synthesize the available evidence regarding the clinical presentation and clinicopathological characteristics, treatment and outcomes. Methods We conducted a systematic literature search using the most important...
Sat Sep 26, 2020 14:24
Abstract Background Chemosaturation with percutaneous hepatic perfusion (CS-PHP; Hepatic CHEMOSAT® Delivery System; Delcath Systems Inc, USA) is a novel interventional procedure, which delivers high doses of melphalan directly to the liver in patients with liver tumors while limiting systemic toxicity through hemofiltration of the hepatic venous blood. We have previously shown promising efficacy for patients with ocular melanoma...
Sat Sep 26, 2020 14:24
Abstract Purpose Glioblastoma (GBM) is the most aggressive type of brain tumor and has poor survival outcomes, even after a combination of surgery, radiotherapy, and chemotherapy. Temozolomide is the only agent that has been shown to be effective against GBM, suggesting that combination of temozolomide with other agents may be more effective. Niclosamide, an FDA approved anthelmintic agent, has shown anti-cancer effects against...
Sat Sep 26, 2020 14:24
Abstract Purpose TP53/EGFR co-mutation has been reported to affect the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in lung adenocarcinoma (LUAD). However, its impact on survival is unclear. In this analysis, we explored the prognostic effect of TP53/EGFR co-mutation in LUAD. Methods Clinical data...
Sat Sep 26, 2020 14:24
Abstract Introduction hTERT (human telomerase reverse transcriptase) is a catalytic subunit of the enzyme telomerase and has a role in cell proliferation, cellular senescence, and human aging. Materials and methods The purpose of this study was to evaluate the expression and significance of hTERT protein expression as a prognostic marker...
Sat Sep 26, 2020 14:24
Abstract Purpose Glioblastoma is the most aggressive form of brain tumors. A better understanding of the molecular mechanisms leading to its evolution is essential for the development of treatments more effective than the available modalities. Here, we aim to identify molecular drivers of glioblastoma development and recurrence by analyzing DNA CpG methylation patterns in sequential samples. ...
Sat Sep 26, 2020 14:24
Abstract Background The goal of this retrospective cohort study was to analyze the association between benign thyroid alteration and thyroid cancer in patients followed in general practices in Germany. Methods Patients aged 18–80 who had received an initial diagnosis of thyroid cancer in one of 1261 general practices in Germany between...
Sat Sep 26, 2020 14:24
Abstract Purpose To investigate the clinicopathological features and survival outcomes between young and old patients with gastric cancer (GC), and further determine the role of young age in the prognosis of GC. Methods Patients with stage I–III gastric adenocarcinomas undergoing curative surgery were enrolled, divided into young (aged...
Sat Sep 26, 2020 14:24
Abstract Purpose Nuclear respiratory factor 1 (NRF1) drives estrogen-dependent breast tumorigenesis. Herein we examined the impact of NRF1 activity on the aggressiveness and disparate molecular signature of breast cancer in Black, White, Asian, and Hispanic women. Methods NRF1 activity by transcription factor target enrichment analysis...
Sat Sep 26, 2020 14:24
Abstract Purpose Although immune checkpoint inhibitors have been shown to be effective in many clinical trials, real-world data remain limited. We investigated the outcomes of non-small cell lung cancer (NSCLC) patients who received nivolumab, with an emphasis on hyper-progressive disease (HPD). Methods This retrospective study enrolled...
Sat Sep 26, 2020 14:24
Abstract Purpose Baseline tumor size (BTS) and the presence of massive lesions are important for predicting the clinical course of cancer. However, their impact on survival and clinical response in patients with advanced NSCLC undergoing immune checkpoint inhibitor (ICI) treatment has been scarcely investigated. Methods We retrospectively...
Sat Sep 26, 2020 14:24
Abstract Purpose Considering the initial treatment of hepatocellular carcinoma (HCC), the best prognostic index for Child–Pugh classes B and C (CP-BC) patients has not been yet established. This study aimed to elucidate the risk factors for disease-free survival (DFS) and overall survival (OS) in multicenter patients with a poor liver functional reserve after curative treatment. ...
Sat Sep 26, 2020 14:24
Abstract Advances in surgery, peri-operative care and systemic chemotherapy have not significantly improved the prognosis of pancreatic cancer for several decades. Early clinical trials of immunotherapy have yielded disappointing results proposing other means by which the tumour microenvironment serves to decrease the immune response. Additionally, the emergence of various subtypes of pancreatic cancer has emerged as a factor for treatment responses with immunogenic subtypes...
Sat Sep 26, 2020 14:24
Abstract Purpose Demethylation of DNA through enzymes like LSD1 showed a crucial impact on different kind of cancers. Epigenetic modifications in cervical cancer are still not fully investigated nevertheless of high interest for a therapeutic use. Methods Tumor samples of 250 cervical cancer patients were immunochemically stained and...
Sat Sep 26, 2020 14:24
Abstract Purpose Everolimus plus exemestane (EVE/EXE) is a registered treatment option for ER-positive, HER2-negative (ER +/HER2-) metastatic breast cancer (MBC), but resistance mechanisms limit efficacy. We aimed to find markers that might help select patients with a higher chance on benefit from EVE/EXE. Methods Immunohistochemistry...
Sat Sep 26, 2020 14:24
Abstract Introduction While hypofractionated stereotactic radiotherapy (HFSRT) is being increasingly used for treating brain metastases, clinical data concerning the incidence and risk factors of its main side-effect, namely radiation necrosis (RN), remain limited. In this context, we assessed risk factors of RN in a single center series of patients with brain metastases treated with three common HFSRT dose regimens: 27 Gy in 3 fractions...
Sat Sep 26, 2020 03:00
38 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/09/26PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Sep 26, 2020 14:26
Related Articles Characterizing Circulating Tumor Cells Isolated from Metastatic Breast Cancer Patients Using Graphene Oxide Based Microfluidic Assay. Adv Biosyst. 2019 02;3(2):e1800278 Authors: Kim TH, Yoon HJ, Fouladdel S, Wang Y, Kozminsky M, Burness ML, Paoletti C, Zhao L, Azizi E, Wicha MS, Nagrath S Abstract The enumeration of circulating tumor cells (CTCs) has shown prognostic importance in patients with breast cancer. However, CTCs are...
Sat Sep 26, 2020 14:32
Related Articles Ovarian cancer and the evolution of subtype classifications using transcriptional profiling†. Biol Reprod. 2019 09 01;101(3):645-658 Authors: Cook DP, Vanderhyden BC Abstract Ovarian cancer is a complex disease with multiple subtypes, each having distinct histopathologies and variable responses to treatment. This review highlights the technological milestones and the studies that have applied them to change our definitions...
Sat Sep 26, 2020 14:32
Related Articles Investigation of BTLA tagging variants with risk of esophagogastric junction adenocarcinoma. Biosci Rep. 2019 12 20;39(12): Authors: Tang W, Chen S, Kang M, Liu J, Liu C Abstract BACKGROUND: Variants in B- and T-lymphocyte attenuator (BTLA) gene are likely to affect the function of BTLA protein. METHODS: In the present case-control study, we selected BTLA tagging single-nucleotide polymorphisms (SNPs) (rs16859629...
Sat Sep 26, 2020 14:32
Related Articles Single-Cell RNA-seq Analysis Reveals a Crucial Role for Collagen Triple Helix Repeat Containing 1 (CTHRC1) Cardiac Fibroblasts after Myocardial Infarction. Circulation. 2020 Sep 25;: Authors: Ruiz-Villalba A, Romero JP, Hernandez SC, Vilas-Zornoza A, Fortelny N, Castro-Labrador L, San Martin-Uriz P, Lorenzo-Vivas E, García-Olloqui P, Palacios M, Gavira JJ, Bastarrika G, Janssens S, Wu M, Iglesias E, Abizanda G, Martinez de Morentin X, Lasaga...
Sat Sep 26, 2020 14:32
Related Articles Economic evaluation of adjuvant trastuzumab therapy for HER2-positive early-stage breast cancer: systematic review and quality assessment. Expert Rev Pharmacoecon Outcomes Res. 2020 Sep 24;:1-10 Authors: Genuino AJ, Gloria MAJ, Chaikledkaew U, Reungwetwattana T, Thakkinstian A Abstract INTRODUCTION: As the availability of new economic evaluations (EE) on adjuvant trastuzumab therapy for early-stage breast cancer (EBC) with HER2-positive...
Sat Sep 26, 2020 14:32
Related Articles Minimally important differences for interpreting European Organisation for Research and Treatment of Cancer (EORTC) Quality of life Questionnaire core 30 scores in patients with ovarian cancer. Gynecol Oncol. 2020 Sep 21;: Authors: Musoro JZ, Coens C, Greimel E, King MT, Sprangers MAG, Nordin A, van Dorst EBL, Groenvold M, Cocks K, Velikova G, Flechtner HH, Bottomley A, EORTC Gynecological and Quality of Life Groups Abstract ...
Sat Sep 26, 2020 14:32
Vulvar cancer subclassification by HPV and p53 status results in three clinically distinct subtypes.
Related Articles Vulvar cancer subclassification by HPV and p53 status results in three clinically distinct subtypes. Gynecol Oncol. 2020 Sep 21;: Authors: Kortekaas KE, Bastiaannet E, van Doorn HC, de Vos van Steenwijk PJ, Ewing-Graham PC, Creutzberg CL, Akdeniz K, Nooij LS, van der Burg SH, Bosse T, van Poelgeest MIE Abstract OBJECTIVE: There is great need for better risk stratification in vulvar squamous cell carcinoma (VSCC). Our aim was...
Sat Sep 26, 2020 14:32
Related Articles Targeting HIF2α-ARNT hetero-dimerisation as a novel therapeutic strategy for Pulmonary Arterial Hypertension. Eur Respir J. 2020 Sep 24;: Authors: Macias D, Moore S, Crosby A, Southwood M, Du X, Tan H, Xie S, Vassallo A, Wood AJ, Wallace EM, Cowburn AS Abstract Pulmonary Arterial Hypertension (PAH) is a destructive disease of the pulmonary vasculature often leading to right heart failure and death. Current therapeutic intervention...
Sat Sep 26, 2020 14:32
Related Articles A proteomic repertoire of autoantigens identified from the classic autoantibody clinical test substrate HEp-2 cells. Clin Proteomics. 2020;17:35 Authors: Wang JY, Zhang W, Rho JH, Roehrl MW, Roehrl MH Abstract Background: Autoantibodies are a hallmark of autoimmune diseases. Autoantibody screening by indirect immunofluorescence staining of HEp-2 cells with patient sera is a current standard in clinical practice. Differential...
Sat Sep 26, 2020 14:32
Related Articles Quantifying Glioblastoma Drug Response Dynamics Incorporating Treatment Sensitivity and Blood Brain Barrier Penetrance From Experimental Data. Front Physiol. 2020;11:830 Authors: Massey SC, Urcuyo JC, Marin BM, Sarkaria JN, Swanson KR Abstract Many drugs investigated for the treatment of glioblastoma (GBM) have had disappointing clinical trial results. Efficacy of these agents is dependent on adequate delivery to sensitive tumor...
Sat Sep 26, 2020 14:32
Related Articles Toll-like receptors and COVID-19: a two-faced story with an exciting ending. Future Sci OA. 2020 Jul 30;6(8):FSO605 Authors: Onofrio L, Caraglia M, Facchini G, Margherita V, Placido S, Buonerba C PMID: 32974046 [PubMed]
Sat Sep 26, 2020 14:32
Related Articles Bladder cancer during the COVID-19 pandemic: the calm before the storm? Future Sci OA. 2020 Aug 03;6(8):FSO615 Authors: Sarkis J, Samaha R, Kattan J, Sarkis P PMID: 32974047 [PubMed]
Sat Sep 26, 2020 14:32
Related Articles Phase 1 Clinical Trials in the Elderly: Enrollment Challenges. J Adv Pract Oncol. 2020 Jul;11(5):494-501 Authors: Guarnieri C, Von Hoff DD Abstract Cancer mostly affects older adults. Despite the increased incidence of cancer among older adults, they are underrepresented in oncology clinical trials. Such trials can provide patients with early access to promising interventions. Clinical trials are changing the future of cancer...
Sat Sep 26, 2020 14:32
Related Articles Immune Monitoring After Allogeneic Hematopoietic Cell Transplantation: Toward Practical Guidelines and Standardization. Front Pediatr. 2020;8:454 Authors: Boelens JJ, Hosszu KK, Nierkens S Abstract Hematopoietic cell transplantation (HCT) is often a last resort, but potentially curative treatment option for children suffering from hematological malignancies and a variety of non-malignant disorders, such as bone marrow failure,...
Sat Sep 26, 2020 14:32
Related Articles Tumor Endothelial Cells (TECs) as Potential Immune Directors of the Tumor Microenvironment - New Findings and Future Perspectives. Front Cell Dev Biol. 2020;8:766 Authors: Nagl L, Horvath L, Pircher A, Wolf D Abstract The tumor microenvironment (TME) plays a central role in cancer development and progression. It represents a complex network of cancer cell (sub-)clones and a variety of stromal cell types. Recently, new technology...
Sat Sep 26, 2020 14:32
Related Articles The Prognostic Value of Axillary Staging Following Neoadjuvant Chemotherapy in Inflammatory Breast Cancer. Ann Surg Oncol. 2020 Sep 24;: Authors: Grova MM, Strassle PD, Navajas EE, Gallagher KK, Ollila DW, Downs-Canner SM, Spanheimer PM Abstract BACKGROUND: Inflammatory breast cancer (IBC) has historically been characterized by high rates of recurrence and poor survival; however, there have been significant improvements in systemic...
Sat Sep 26, 2020 14:32
Related Articles Gilteritinib use in the treatment of relapsed or refractory acute myeloid leukemia with a FLT3 mutation. Future Oncol. 2020 Sep 25;: Authors: Ballesta-López O, Solana-Altabella A, Megías-Vericat JE, Martínez-Cuadrón D, Montesinos P Abstract The prognosis of patients with relapsed or refractory acute myeloid leukemia (R/R AML) is dismal with salvage standard approaches, and mutations of FMS-like tyrosine kinase 3 (FLT3) gene,...
Sat Sep 26, 2020 14:32
Related Articles Much is left unspoken: Self-reports from families in pediatric oncology. Pediatr Blood Cancer. 2020 Sep 25;:e28735 Authors: Lövgren M, Udo C, Alvariza A, Kreicbergs U Abstract BACKGROUND: Communication about illness-related subjects is complex and difficult. To support entire families in pediatric oncology, health care professionals need to know what family members think, but leave unspoken. The aim of this study was to explore...
Sat Sep 26, 2020 14:32
Related Articles Sentinel node biopsy in conservative surgery for breast cancer: a changing role in clinical practice. Minerva Chir. 2020 Sep 25;: Authors: Magnoni F, Veronesi P Abstract Recent studies have demonstrated that the extent of surgical treatment in both breast and axilla can be minimized through a multimodal and personalized management, based on assessment of breast cancer (BC) molecular subtypes, genetics and on the prevailing relevance...
Sat Sep 26, 2020 14:32
Related Articles "I think that a brief conversation from their provider can go a very long way": Patient and provider perspectives on barriers and facilitators of genetic testing after ovarian cancer. Support Care Cancer. 2020 Sep 25;: Authors: Mallen AR, Conley CC, Fuzzell L, Ketcher D, Augusto BM, McIntyre M, Barton LV, Townsend MK, Fridley BL, Tworoger SS, Wenham RM, Vadaparampil ST Abstract OBJECTIVE: Identify predisposing, enabling, and...
Sat Sep 26, 2020 14:32
Related Articles Clinical applications of circulating tumor DNA in monitoring breast cancer drug resistance. Future Oncol. 2020 Sep 25;: Authors: Liu Y, Du Q, Sun D, Han R, Teng M, Chen S, You H, Dong Y Abstract Breast cancer is one of the leading causes of cancer-related deaths in women worldwide. Unfortunately, treatments often fail because of the development of drug resistance, the underlying mechanisms of which remain unclear. Circulating...
Sat Sep 26, 2020 14:32
Related Articles Role of indoleamine 2,3-dioxygenase in acute myeloid leukemia. Future Oncol. 2020 Sep 25;: Authors: Sobash PT, Kolhe R, Karim NA, Guddati AK, Jillella A, Kota V Abstract Indoleamine 2,3 dioxygenase (IDO), first discovered in the 1960s, is an enzyme that has become a highly investigated metabolic target in cancer research. IDO is the rate-limiting step in tryptophan metabolism catabolism into its byproducts - kynurenines. Both...
Sat Sep 26, 2020 14:32
Related Articles A theoretical model of financial burden after cancer diagnosis. Future Oncol. 2020 Sep 25;: Authors: Jones SM, Henrikson NB, Panattoni L, Syrjala KL, Shankaran V Abstract Current models of financial burden after cancer do not adequately define types of financial burden, moderators or causes. We propose a new theoretical model to address these gaps. This model delineates the components of financial burden as material and psychological...
Sat Sep 26, 2020 14:32
Related Articles Demographic factors associated with missed follow-up among solid tumor patients treated at a large multi-site academic institution. Future Oncol. 2020 Sep 25;: Authors: Freije SL, Holmes JA, Rachidi S, Ellsworth SG, Zellars RC, Lautenschlaeger T Abstract Aim: To identify demographic predictors of patients who miss oncology follow-up, considering that missed follow-up has not been well studies in cancer patients. Methods: Patients...
Sat Sep 26, 2020 14:32
Pharmacogenomics in Pediatric Oncology: Mitigating Adverse Drug Reactions While Preserving Efficacy.
Related Articles Pharmacogenomics in Pediatric Oncology: Mitigating Adverse Drug Reactions While Preserving Efficacy. Annu Rev Pharmacol Toxicol. 2020 Sep 25;: Authors: Elzagallaai AA, Carleton BC, Rieder MJ Abstract Cancer is the leading cause of death in American children older than 1 year of age. Major developments in drugs such as thiopurines and optimization in clinical trial protocols for treating cancer in children have led to a remarkable...
Sat Sep 26, 2020 14:32
Related Articles Oligometastasis: Past, Present, Future. Int J Radiat Oncol Biol Phys. 2020 Nov 01;108(3):530-538 Authors: Gutiontov SI, Pitroda SP, Weichselbaum RR Abstract In this review, we discuss the oligometastatic state, with a focus on its current and future relevance within the field of radiation therapy. We first outline the scope of the problem and the evolving understanding of metastatic disease existing along a spectrum. We then...
Sat Sep 26, 2020 14:32
Related Articles Major Depressive Disorder and gut microbiota - Association not causation. A scoping review. Prog Neuropsychopharmacol Biol Psychiatry. 2020 Sep 22;:110111 Authors: Łoniewski I, Misera A, Skonieczna-Żydecka K, Kaczmarczyk M, Kaźmierczak-Siedlecka K, Misiak B, Marlicz W, Samochowiec J Abstract One very promising hypothesis of Major Depressive Disorder (MDD) pathogenesis is the gut-brain axis (GBA) dysfunction, which can lead to...
Sat Sep 26, 2020 14:32
Related Articles Ureteral injury during left colectomy for cancer: Laparoscopic management. A case report. Int J Surg Case Rep. 2020 Sep 12;: Authors: Di Buono G, Bonventre G, Buscemi S, Maienza E, Romano G, Agrusa A Abstract INTRODUCTION: Iatrogenic ureteral lesions may occur after any abdominal and pelvic surgery. They are severe and can affect renal function and even vital prognosis. This study aimed to determine the clinical aspects and...
Sat Sep 26, 2020 14:51
Related Articles Successful laparoscopic management of congenital diaphragmatic relaxation: A case report. Int J Surg Case Rep. 2020 Sep 10;: Authors: Di Buono G, Bonventre G, Amato G, Ricupati F, Romano G, Agrusa A Abstract INTRODUCTION: Diaphragmatic relaxation is an infrequent condition characterized by a permanent elevation of all or part of an hemidiaphragm which maintains its insertions on the ribs and which does not have continuous solutions...
Sat Sep 26, 2020 14:51
Related Articles Recurrent intussusception of small bowel in a young patient due to metastases from cardiac undifferentiated pleomorphic sarcoma: A first ever case report. Int J Surg Case Rep. 2020 Sep 14;: Authors: Di Buono G, Randisi B, Romano G, Ricupati F, Buscemi S, Agrusa A Abstract INTRODUCTION: Undifferentiated metastatic pleomorphic sarcoma (Malignant Fibrous Histiocytoma) is a rare entity in the small intestine, especially when the...
Sat Sep 26, 2020 14:51
Related Articles Combined endo-laparoscopic treatment of large gastrointestinal stromal tumor of the stomach: Report of a case and literature review. Int J Surg Case Rep. 2020 Sep 10;: Authors: Di Buono G, Maienza E, Buscemi S, Bonventre G, Romano G, Agrusa A Abstract INTRODUCTION: Gastrointestinal stromal tumours (GISTs) are the most common malignant subepithelial lesions of gastrointestinal tract, originating from Cajal's cells and characterized...
Sat Sep 26, 2020 14:51
Related Articles Ultrasound guided percutaneous dilatation tracheotomy (US-PDT) to prevent potentially life-threatening complications: A case report. Int J Surg Case Rep. 2020 Sep 12;: Authors: Gualtieri G, Imperatore F, Cafora C, Liguori G, Gritti F, Tolone S, Brusciano L, Parisi S, Terracciano G, Gambardella C, Ruggiero R, Docimo L Abstract INTRODUCTION: Percutaneous dilatation tracheotomy (PDT) is a relatively recent technique that enables...
Sat Sep 26, 2020 14:51
Related Articles Giant solitary fibrous tumor of the pelvis: A case report and review of literature. Int J Surg Case Rep. 2020 Sep 10;: Authors: Palmieri G, Grassi C, Conti L, Banchini F, Daccò MD, Cattaneo GM, Capelli P Abstract INTRODUCTION: Solitary fibrous tumors (SFTs) are rare spindle cells neoplasms most likely arising from mesenchymal cells. Usually they involve the pleura. Even if extra-thoracic SFTs are rare, lately they are diagnosed...
Sat Sep 26, 2020 14:51
Related Articles The colovescical fistula in diverticular disease: Laparoscopic approach in two different cases. Int J Surg Case Rep. 2020 Sep 11;: Authors: Di Buono G, Bonventre G, Buscemi S, Randisi B, Romano G, Agrusa A Abstract INTRODUCTION: The colovescical fistula is one of the complications of diverticular disease. It can cause significant symptoms like pneumaturia and fecaluria affecting the quality of life and sometimes leading to death,...
Sat Sep 26, 2020 14:51
Related Articles Small bowel obstruction after caesarean section: Laparoscopic management. Two case report. Int J Surg Case Rep. 2020 Sep 14;: Authors: Di Buono G, Ricupati F, Maienza E, Gulotta L, Buscemi S, Agrusa A Abstract INTRODUCTION: Caesarean section is the most common abdominal surgery performed on women worldwide. Adhesions represent a severe complication of cesarean section and can cause different degrees of bowel obstruction. ...
Sat Sep 26, 2020 14:51
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