Related Articles Prognostic and Predictive Value of Tumor-Infiltrating Immune Cells in Urothelial Cancer of the Bladder. Cancers (Basel). 2020 Sep 21;12(9): Authors: van Wilpe S, Gerretsen ECF, van der Heijden AG, de Vries IJM, Gerritsen WR, Mehra N Abstract The prognosis and responsiveness to chemotherapy and checkpoint inhibitors differs substantially among patients with bladder cancer (BC). There is an unmet need for biomarkers that can accurately...
Related Articles Extraskeletal Myxoid Chondrosarcoma: State of the Art and Current Research on Biology and Clinical Management. Cancers (Basel). 2020 Sep 21;12(9): Authors: Stacchiotti S, Baldi GG, Morosi C, Gronchi A, Maestro R Abstract Extraskeletal myxoid chondrosarcoma (EMC) is an ultra-rare mesenchymal neoplasm with uncertain differentiation, which arises mostly in the deep soft tissue of proximal extremities and limb girdles. EMC is marked...
Related Articles Visualization of the distribution of nanoparticle-formulated AZD2811 in mouse tumor model using matrix-assisted laser desorption ionization mass spectrometry imaging. Sci Rep. 2020 Sep 23;10(1):15535 Authors: Ryu S, Ohuchi M, Yagishita S, Shimoi T, Yonemori K, Tamura K, Fujiwara Y, Hamada A Abstract Penetration of nanoparticles into viable tumor regions is essential for an effective response. Mass spectrometry imaging (MSI)...
Related Articles Long-term cognitive deficits in pediatric low-grade glioma (LGG) survivors reflect pretreatment conditions-report from the German LGG studies. Neurooncol Adv. 2020 Jan-Dec;2(1):vdaa094 Authors: Traunwieser T, Kandels D, Pauls F, Pietsch T, Warmuth-Metz M, Bison B, Krauss J, Kortmann RD, Timmermann B, Thomale UW, Luettich P, Neumann-Holbeck A, Tischler T, Hernáiz Driever P, Witt O, Gnekow AK Abstract Background: Disease and treatment...
Related Articles Remote symptom monitoring integrated into electronic health records: A systematic review. J Am Med Inform Assoc. 2020 Sep 23;: Authors: Gandrup J, Ali SM, McBeth J, van der Veer SN, Dixon WG Abstract OBJECTIVE: People with long-term conditions require serial clinical assessments. Digital patient-reported symptoms collected between visits can inform these, especially if integrated into electronic health records (EHRs) and clinical...
Related Articles The impact of single nucleotide polymorphisms in ADORA2A and ADORA3 genes on the early response to methotrexate and presence of therapy side effects in children with juvenile idiopathic arthritis: Results of a preliminary study. Int J Rheum Dis. 2020 Sep 23;: Authors: Roszkiewicz J, Michałek D, Ryk A, Swacha Z, Szmyd B, Smolewska E Abstract AIM: Methotrexate (MTX) administered at the dose 10-15 mg/m2 is recommended as the first-line...
Related Articles Image-guided percutaneous microwave ablation of early-stage non-small cell lung cancer. Asia Pac J Clin Oncol. 2020 Sep 24;: Authors: Ni Y, Xu H, Ye X Abstract Although surgical lobectomy with systematic mediastinal lymph node evaluation is considered as the "gold standard" for management of early stage non-small cell lung cancer (NSCLC), image-guided percutaneous thermal ablation has been increasingly used for medically inoperable...
Related Articles Identification of hub genes and discovery of promising compounds in gastric cancer based on bioinformatics analysis. Biomark Med. 2020 Aug;14(12):1069-1084 Authors: Huang J, Wen F, Huang W, Bai Y, Lu X, Shu P Abstract Aim: To explore the mechanism of gastric carcinogenesis by mining potential hub genes and to search for promising small-molecular compounds for gastric cancer (GC). Materials & methods: The microarray datasets...
Related Articles D-dimer enhances risk targeted thromboprophylaxis in ambulatory cancer patients. Oncologist. 2020 Sep 24;: Authors: Kumar V, Shaw J, Key NS, Ilich A, Mallick R, Wells P, Carrier M Abstract BACKGROUND: Thromboprophylaxis for ambulatory cancer patients is effective, although uncertainties remain on who should be targeted. Using D-dimer values from individuals enrolled to the AVERT trial, we sought to identify and validate a more...
Related Articles Integrated genomic analysis identifies a genetic mutation model predicting response to immune checkpoint inhibitors in melanoma. Cancer Med. 2020 Sep 24;: Authors: Jiang J, Ding Y, Wu M, Chen Y, Lyu X, Lu J, Wang H, Teng L Abstract Several biomarkers such as tumor mutation burden (TMB), neoantigen load (NAL), programmed cell-death receptor 1 ligand (PD-L1) expression, and lactate dehydrogenase (LDH) have been developed for predicting...
Related Articles History through the eyes of a pandemic. Curr Opin Ophthalmol. 2020 Sep 21;: Authors: Graversen VK, Hamichi SE, Gold A, Murray TG Abstract PURPOSE: This review provides a historic perspective of the impact that major pandemics have had on human and their relationship with ophthalmology. The novel coronavirus epidemic is also analyzed, highlighting the relevance of the eye as a possible source of transmission, infection, and prognosis...
Related Articles COVID-19 and neurological training in Europe: from early challenges to future perspectives. Neurol Sci. 2020 Sep 24;: Authors: van der Meulen M, Kleineberg NN, Schreier DR, García-Azorin D, Di Lorenzo F Abstract The worldwide SARS-CoV-2 pandemic is dramatically affecting health systems with consequences also for neurological residency training. Here we report early experiences and challenges that European neurologists and residents...
Related Articles Prognostic significance of sarcopenia in microsatellite-stable gastric cancer patients treated with programmed death-1 inhibitors. Gastric Cancer. 2020 Sep 24;: Authors: Kim YY, Lee J, Jeong WK, Kim ST, Kim JH, Hong JY, Kang WK, Kim KM, Sohn I, Choi D Abstract BACKGROUND: Sarcopenia has been underscored as a significant predictor of poor prognosis in cancer patients undergoing immunotherapy with programmed death-1 (PD-1) inhibitors....
Related Articles Dexamethasone dosing for prevention of acute chemotherapy-induced vomiting in pediatric patients: A systematic review. Pediatr Blood Cancer. 2020 Sep 24;:e28716 Authors: Patel P, Olteanu A, Cabral S, Santesso N, Robinson PD, Dupuis LL Abstract A systematic review was undertaken to describe dexamethasone doses studied for chemotherapy-induced vomiting (CIV) prophylaxis in pediatric patients and their effects on achieving complete...
Related Articles Targeting the intrinsically disordered architectural High Mobility Group A (HMGA) oncoproteins in breast cancer: learning from the past to design future strategies. Expert Opin Ther Targets. 2020 Sep 24;:1-17 Authors: Pegoraro S, Ros G, Sgubin M, Petrosino S, Zambelli A, Sgarra R, Manfioletti G Abstract INTRODUCTION: Triple-negative breast cancer (TNBC) is the most difficult breast cancer subtype to treat because of its heterogeneity...
Related Articles Telehealth for Cancer Care in Veterans: Opportunities and Challenges Revealed by COVID. JCO Oncol Pract. 2020 Sep 24;:OP2000520 Authors: Jiang CY, El-Kouri NT, Elliot D, Shields J, Caram MEV, Frankel TL, Ramnath N, Passero VA Abstract The Veterans Health Administration system is one of the largest integrated health care providers in the United States, delivering medical care to > 9 million veterans. Barriers to delivering...
Related Articles Role and mechanism of autophagy-regulating factors in tumorigenesis and drug resistance. Asia Pac J Clin Oncol. 2020 Sep 24;: Authors: Usman RM, Razzaq F, Akbar A, Farooqui AA, Iftikhar A, Latif A, Hassan H, Zhao J, Carew JS, Nawrocki ST, Anwer F Abstract A hallmark feature of tumorigenesis is uncontrolled cell division. Autophagy is regulated by more than 30 genes and it is one of several mechanisms by which cells maintain...
Related Articles Combination of Olaparib and radiotherapy for triple negative breast cancer: preliminary results of the RADIOPARP phase I trial. Int J Radiat Oncol Biol Phys. 2020 Sep 21;: Authors: Loap P, Loirat D, Berger F, Ricci F, Vincent-Salomon A, Ezzili C, Mosseri V, Fourquet A, Ezzalfani M, Kirova Y Abstract PURPOSE: Preclinical studies have evidenced that triple-negative breast cancer (TNBC) cell lines are more sensitive to poly (ADP-ribose)...
Related Articles Italian Young Doctors' knowledge, attitude and practices on antibiotic use and resistance: A national cross-sectional survey. J Glob Antimicrob Resist. 2020 Sep 21;: Authors: Di Gennaro F, Marotta C, Amicone M, Bavaro DF, Bernaudo F, Frisicale EM, Kurotschka PK, Mazzari A, Veronese N, Murri R, Fantoni M Abstract OBJECTIVES: Antimicrobial resistance (AMR) is one of the major health issues world-wide. Clinicians should play a...
Abstract Purpose Recent research in epilepsy patients confirms our understanding of epilepsy as a network disorder with widespread cortical compromise. Here, we aimed to investigate the neocortical laminar architecture in patients with focal cortical dysplasia (FCD) and periventricular nodular heterotopia (PNH) using clinically feasible 3 T MRI. Methods ...
Publication date: Available online 24 September 2020Source: Journal of VoiceAuthor(s): Paul M. Patinka, Jesus De Hoyos, James Rodriguez
Publication date: Available online 24 September 2020Source: Journal of VoiceAuthor(s): Vanessa Mika Kinchoku, Rui Imamura, Adriana Hachiya, Rosiane Yamasaki, Luiz Ubirajara Sennes, Domingos Hiroshi Tsuji
Publication date: Available online 24 September 2020Source: Journal of VoiceAuthor(s): Ian Vince McLoughlin, Olivier Perrotin, Hamid Sharifzadeh, Jacqui Allen, Yan Song
Related Articles Pyrenocine A induces monopolar spindle formation and suppresses proliferation of cancer cells. Bioorg Med Chem. 2019 12 01;27(23):115149 Authors: Myobatake Y, Kamisuki S, Tsukuda S, Higashi T, Chinen T, Takemoto K, Hachisuka M, Suzuki Y, Takei M, Tsurukawa Y, Maekawa H, Takeuchi T, Matsunaga TM, Sahara H, Usui T, Matsunaga S, Sugawara F Abstract Pyrenocine A, a phytotoxin, was found to exhibit cytotoxicity against cancer cells...
Related Articles NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor. Cell Rep. 2019 11 05;29(6):1469-1481.e9 Authors: Bury M, Le Calvé B, Lessard F, Dal Maso T, Saliba J, Michiels C, Ferbeyre G, Blank V Abstract Constitutive nuclear factor κB (NF-κB) activation is a hallmark of colon tumor growth. Cyclin-dependent kinases (CDKs) are critical cell-cycle regulators, and inhibition of CDK activity has been used...
Related Articles A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation. Nucleic Acids Res. 2020 08 20;48(14):7844-7855 Authors: Guarino Almeida E, Renaudin X, Venkitaraman AR Abstract The catalytic activity of human AURORA-A kinase (AURKA) regulates mitotic progression, and its frequent overexpression in major forms of epithelial cancer is associated with aneuploidy and carcinogenesis. Here, we...
Related Articles Ceruloplasmin oxidized and deamidated by Parkinson's disease cerebrospinal fluid induces epithelial cells proliferation arrest and apoptosis. Sci Rep. 2020 Sep 23;10(1):15507 Authors: Barbariga M, Zanardi A, Curnis F, Conti A, Boselli D, Di Terlizzi S, Alessio M Abstract In Parkinson's disease, the ferroxidase ceruloplasmin (Cp) is oxidized and deamidated by the pathological cerebrospinal fluid (CSF) environment. These...
Related Articles Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models. PLoS One. 2020;15(9):e0239315 Authors: Pinto N, Prokopec SD, Ghasemi F, Meens J, Ruicci KM, Khan IM, Mundi N, Patel K, Han MW, Yoo J, Fung K, MacNeil D, Mymryk JS, Datti A, Barrett JW, Boutros PC, Ailles L, Nichols AC Abstract Anaplastic thyroid cancer (ATC) is a rare, but nearly uniformly fatal disease that...
Related Articles Whole-transcriptome sequencing (RNA-seq) study of the ZFL zebrafish liver cell line after acute exposure to Cd2+ ions. Aquat Toxicol. 2020 Sep 15;228:105628 Authors: Kwok ML, Meng Q, Hu XL, Chung CT, Chan KM Abstract Cadmium (Cd) is a non-essential metal with no known biological function and a broad range of toxic effects in biological systems. We used whole-transcriptome sequencing (RNA-seq) to study the effects of Cd2+...
Publication date: 15 January 2021Source: Talanta, Volume 222Author(s): Ondřej Horáček, Monika Papajová-Janetková, Bohumír Grüner, Lukáš Lochman, Petra Štěrbová-Kovaříková, Radim Vespalec, Radim Kučera
Related Articles Peaks in online inquiries into pharyngitis-related symptoms correspond with annual incidence rates. Eur Arch Otorhinolaryngol. 2020 Sep 23;: Authors: Brkic FF, Besser G, Janik S, Gadenstaetter AJ, Parzefall T, Riss D, Liu DT Abstract OBJECTIVE: To assess whether web-based public inquiries into pharyngitis-related search terms follow annual incidence peaks of acute pharyngitis in various countries from both hemispheres. ...
Related Articles Teaching middle ear anatomy using a novel three-dimensional papercraft model. Eur Arch Otorhinolaryngol. 2020 Sep 24;: Authors: Guy J, Muzaffar J, Coulson C Abstract BACKGROUND: The middle ear is a complex anatomical space which is difficult to interpret from two-dimensional imagery. Appropriate surgical knowledge of the area is required to operate, yet current anatomical teaching methods are costly and hard to access for the...
Publication date: Available online 25 September 2020Source: Acta Otorrinolaringológica EspañolaAuthor(s): Olindo Massarelli, Luigi Angelo Vaira, Giacomo De Riu
New England Journal of Medicine, Ahead of Print.
Thu Sep 24, 2020 06:15
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Publication date: Available online 24 September 2020Source: NeuroImageAuthor(s): Yuqing Zhou, Shihui Han
Publication date: Available online 24 September 2020Source: NeuroImageAuthor(s): F. von Wegner, S. Bauer, F. Rosenow, J. Triesch, H. Laufs
Publication date: Available online 24 September 2020Source: NeuroImageAuthor(s): Lau Hoi Yan Gladys, Alex Fornito, Ben D. Fulcher
Publication date: Available online 24 September 2020Source: NeuroImageAuthor(s): Nicola K. Dinsdale, Emma Bluemke, Stephen M. Smith, Zobair Arya, Diego Vidaurre, Mark Jenkinson, Ana I.L. Namburete
Abstract Improvement in suffering after treatment has been poorly investigated in women affected with vulvar lichen sclerosus (VLS). We performed an observational study on a cohort of VLS patients for assessing the effect of a 12‐week topical corticosteroid treatment on their VLS‐related burden, as measured with Pictorial Representation of Illness and Self‐Measure (PRISM) and Dermatology Life Quality Index (DLQI). Demographics and disease‐related subjective and objective scores (at baseline, T0,...
Abstract Burnout among physicians and dermatologists is gaining a wide attention in the recent decade. The aim of this cross sectional study was to assess the prevalence and predicting factors for burnout among Egyptian dermatologists. A cross sectional study was designed and data were collected using structured open access survey. A total of 144 dermatologists completed the full questionnaire. The majority of dermatologists completing the survey 85 (59%) were between 30‐40 years age group while...
Abstract Residual psoriasis characterizes body sites resistant to biologic drugs. Some affected body sites exert disproportionate impact on patients' quality of life. The aim was to localize residual psoriasis in patients treated with biologics for at least 6 months, and to study the correlation between lesional localization and patients' quality of life. Current Psoriasis Area and Severity Index (PASI) and Nail Psoriasis Severity Index (NAPSI) were assessed. Quality of life was obtained by measuring...
ABSTRACT Objective The aim of this study is to investigate the demographic and clinical characteristics of patients receiving biological therapy for psoriasis. Material and Methods All patients who received biological treatment for psoriasis were included in the study. Characteristics of patients and PASI responses’ rates were evaluated at 6, 12, 16, 24, 36, and 52 weeks. Results One hundred and three patients enrolled. Of all, 28 patients were using adalimumab (27.2%), 26 were using...
Related Articles COVID-19 pandemic: Monitoring space-time data and learning from global experience. Exp Ther Med. 2020 Nov;20(5):73 Authors: Symvoulakis EK, Sourvinos G, Spandidos DA, Lionis C Abstract COVID-19 pandemic is a reality. This study extracted information from a case in Italy and a case in South Korea during COVID-19 pandemic. Epidemic threat evolved differently in Italy compared to that in South Korea. Case fatality ratios from Italy...
Related Articles Isoflurane suppresses lung ischemia-reperfusion injury by inactivating NF-κB and inhibiting cell apoptosis. Exp Ther Med. 2020 Nov;20(5):74 Authors: Lv N, Li X Abstract Patients with lung ischemia-reperfusion injury (LIRI), involving cytokines, including interleukin (IL)-6 and IL-8, display poor clinical outcomes. Isoflurane displays protective effects against ischemia-reperfusion injury in numerous organs. In the present study,...
Related Articles Comparison of pancreatic function and quality of life between patients with infected pancreatitis necrosis undergoing open necrosectomy and minimally invasive drainage: A long-term study. Exp Ther Med. 2020 Nov;20(5):75 Authors: Tu J, Zhang J, Yang Y, Xu Q, Ke L, Tong Z, Li W, Li J Abstract The present study aimed to determine whether a difference in pancreatic function and quality of life (QoL) is present between patients with...
Related Articles Mechanisms of the lipopolysaccharide-induced inflammatory response in alveolar epithelial cell/macrophage co-culture. Exp Ther Med. 2020 Nov;20(5):76 Authors: Li J, Qin Y, Chen Y, Zhao P, Liu X, Dong H, Zheng W, Feng S, Mao X, Li C Abstract The interaction between alveolar epithelial cells (EpCs) and macrophages (MPs) serves an important role in initiating and maintaining inflammation in chronic pulmonary diseases. The aim of...
Related Articles SPAG5 is associated with unfavorable prognosis in patients with lung adenocarcinoma and promotes proliferation, motility and autophagy in A549 cells. Exp Ther Med. 2020 Nov;20(5):77 Authors: Huang R, Li A Abstract Sperm-associated antigen 5 (SPAG5) is involved in the tumorigenesis of multiple cancer types. However, the role of SPAG5 during lung adenocarcinoma (LUAD) progression remains to be fully elucidated. In the present...
Related Articles Advancing COVID-19 differentiation with a robust preprocessing and integration of multi-institutional open-repository computer tomography datasets for deep learning analysis. Exp Ther Med. 2020 Nov;20(5):78 Authors: Trivizakis E, Tsiknakis N, Vassalou EE, Papadakis GZ, Spandidos DA, Sarigiannis D, Tsatsakis A, Papanikolaou N, Karantanas AH, Marias K Abstract The coronavirus pandemic and its unprecedented consequences globally...
Related Articles Bone morphogenetic protein 2-enhanced osteogenic differentiation of stem cell spheres by regulation of Runx2 expression. Exp Ther Med. 2020 Nov;20(5):79 Authors: Min SK, Kim M, Park JB Abstract Bone morphogenetic protein 2 (BMP-2) is a growth factor that is used to induce osteogenic differentiation in stem cells. The present study assessed the effects of BMP-2 on stem cell spheroid morphology, viability and osteogenic differentiation....
Caduet enhances connexin 43 phosphorylation in left ventricular and thoracic aorta of SH model rats.
Related Articles Caduet enhances connexin 43 phosphorylation in left ventricular and thoracic aorta of SH model rats. Exp Ther Med. 2020 Nov;20(5):80 Authors: Huang X, Yang J, Song B, Wang N, Ma M, Wang H, Wang S, Hao S, Cheng G Abstract Caduet, also known as amlodipine besylate and atorvastatin calcium (AM + AT) tablet, can improve cardiac and vascular remodeling in patients with spontaneous hypertension (SH), but the underlying mechanism remains...
Related Articles Osteogenic differentiation and inflammatory response of recombinant human bone morphogenetic protein-2 in human maxillary sinus membrane-derived cells. Exp Ther Med. 2020 Nov;20(5):81 Authors: Chun J, Jung J, Lee JH, Oh SH, Kwon YD Abstract The aim of the present study was to investigate the osteogenic potential of human maxillary sinus membrane (hMSM)-derived cells, and the role of recombinant human bone morphogenetic protein-2...
Related Articles The compound 2-benzylthio-5,8-dimethoxynaphthalene-1,4-dione leads to apoptotic cell death by increasing the cellular reactive oxygen species levels in Ras-mutated liver cancer cells. Exp Ther Med. 2020 Nov;20(5):82 Authors: Shen GN, Li J, Jin YH, Sun HN, Hao YY, Jin MH, Liu R, Li WL, Zhang YQ, Yu JB, Yu NN, Wang WD, Yu LY, Kim JS, Kwon T, Han YH Abstract The aim of the present study was to verify the pro-apoptotic anticancer...
Related Articles Oxidative stress is important in the pathogenesis of stress-related mucosal disease. Exp Ther Med. 2020 Nov;20(5):83 Authors: Wang X, Zhao Q, Shi H, Qi F, Shi N, Bai D, Li X, Yuan H, Zuo X Abstract Stress-related mucosal disease (SRMD) is a common complication in patients in the intensive care unit (ICU). The aim of the present study was to investigate the possible mechanisms for the pathogenesis of SRMD. In total, 38 patients...
Related Articles Effects of CD4+ T lymphocytes from ovariectomized mice on bone marrow mesenchymal stem cell proliferation and osteogenic differentiation. Exp Ther Med. 2020 Nov;20(5):84 Authors: Shao BY, Wang L, Yu Y, Chen L, Gan N, Huang WM Abstract The present study was designed to investigate the effects of T cells on the proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells (BMMSCs). BMMSCs were co-cultured...
Related Articles MicroRNA-503-5p improves carotid artery stenosis by inhibiting the proliferation of vascular smooth muscle cells. Exp Ther Med. 2020 Nov;20(5):85 Authors: Yan Z, Wang H, Liang J, Li Y, Li X Abstract Carotid artery stenosis (CAS) is a common arteriosclerotic vascular disease affected by vascular smooth muscle cells (VSMCs). The aim of the present study was to investigate the expression and diagnostic value of microRNA (miR)-503-5p...
Related Articles Diagnostic value of VDBP and miR-155-5p in diabetic nephropathy and the correlation with urinary microalbumin. Exp Ther Med. 2020 Nov;20(5):86 Authors: Bai X, Luo Q, Tan K, Guo L Abstract This study explored the diagnostic and therapeutic significance of vitamin D binding protein (VDBP) and miR-155-5p for diabetic nephropathy and the correlation with urinary microalbumin. A total of 145 patients with type 2 diabetes who attended...
Related Articles Correlation of TNF-α and IL-10 gene polymorphisms with primary nephrotic syndrome. Exp Ther Med. 2020 Nov;20(5):87 Authors: Xiao M, Bai S, Chen J, Xie L, Li Y, Li Y, Zhang S, Wu Y, Tan G, Wang W, Wang Y, Quan L, Hu Z Abstract The study explored the correlations of tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) gene polymorphisms with susceptibility and the condition of primary nephrotic syndrome. A total of 200 patients...
Related Articles Nephrotoxicity of cypermethrin in rats. Histopathological aspects. Histol Histopathol. 2020 Sep 24;:18263 Authors: Alalwani AD Abstract Cypermethrin (CYP) is an important type II pyrethroid pesticide widely used to protect crops against pests and insect infestations. However, its toxicity is a risk to both human health and the surrounding environment. The present study was conducted to investigate the nephrotoxic effect and...
Abstract Albinism is a rare genetic condition associated with profound visual alterations and a variable hypopigmentation phenotype. The impairment of the visual system includes diagnostic foveal hypoplasia along with misrouting of retinal axons at the optic chiasm, whose consequences are a reduced visual acuity and altered stereoscopic vision, respectively. It is assumed that between 1:10,000‐20,000 newborns can be a person with albinism, with great variations depending on world areas.
Abstract Oculocutaneous albinism (OCA), which is roughly divided into non‐syndromic and syndromic OCA, is a group of autosomal recessive disorders caused by mutations in genes associated with pigmentation. Patients with OCA have hypopigmentation and ocular manifestations such as photophobia, amblyopia, and nystagmus. Hermansky‐Pudlak syndrome (HPS), the most common syndromic OCA, is characterized by the additional features of a bleeding tendency and other critical systemic comorbidities such as...
Related Articles Fluoxetine adjunct to therapeutic exercise promotes motor recovery in rats with cerebral ischemia: Roles of nucleus accumbens. Brain Res Bull. 2019 11;153:1-7 Authors: Hua Y, Li C, Hu J, Wang YY, Liu PL, Gao BY, Chen C, Xu DS, Zhang B, Bai YL Abstract The study aimed to explore the molecular mechanism of fluoxetine as an adjunct to therapeutic exercise to improve motor recovery using a rat cerebral ischemic model with middle...
Related Articles Acute cerebral infarction with adenomyosis in a patient with fever: a case report. BMC Neurol. 2020 May 25;20(1):210 Authors: Zhao Y, Zhang Y, Yang Y Abstract BACKGROUND: It is reported that acute cerebral infarction with adenomyosis is associated with elevated D-Dimer, elevated CA125, anemia and menstruation. However, previous reports did not notice infection known as fever, which may be a potential risk factor for developing...
Related Articles Vagus nerve stimulation reduces spreading depolarization burden and cortical infarct volume in a rat model of stroke. PLoS One. 2020;15(7):e0236444 Authors: Lindemann J, Rakers C, Matuskova H, Simon BJ, Kinfe T, Petzold GC Abstract Cortical spreading depolarization (SD) waves negatively affect neuronal survival and outcome after ischemic stroke. We here aimed to investigate the effects of vagus nerve stimulation (VNS) on SDs...
Related Articles The management of suspected or confirmed laryngopharyngeal reflux patients with recalcitrant symptoms: A contemporary review. Clin Otolaryngol. 2019 09;44(5):784-800 Authors: Lechien JR, Muls V, Dapri G, Mouawad F, Eisendrath P, Schindler A, Nacci A, Barillari MR, Finck C, Saussez S, Akst LM, Sataloff RT Abstract OBJECTIVE: To summarise current knowledge about the prevalence, aetiology and management of recalcitrant laryngopharyngeal...
Related Articles Swallowing Characteristics in Zenker's-like Diverticulum After Anterior Cervical Spine Surgery. Laryngoscope. 2020 06;130(6):1383-1387 Authors: Dhar SI, Wegner AM, Rodnoi P, Wuellner JC, Mehdizadeh OB, Shen SC, Nachalon Y, Nativ-Zeltzer N, Klineberg EO, Belafsky PC Abstract OBJECTIVES: A Zenker's diverticulum (ZD) is a hypopharyngeal pulsion diverticula caused by dysfunction of the cricopharyngeus muscle with herniation of...
Related Articles Clinical utility and effectiveness of a training programme in the application of a new classification of narrow-band imaging for vocal cord leukoplakia: A multicentre study. Clin Otolaryngol. 2019 09;44(5):729-735 Authors: Ni XG, Wang GQ, Hu FY, Xu XM, Xu L, Liu XQ, Chen XS, Liu L, Ren XL, Yang Y, Guo L, Gu YJ, Hou J, Zhang JW, Yang Y, Xing B, Ren J, Guo HQ Abstract OBJECTIVE: To analyse the application of a new narrow-band...
Related Articles Successful Use of High-Flow Nasal Cannula for Concurrent Vocal Cord Electromyography and Tubeless Microlaryngeal Surgery in a Spontaneously Breathing Adult Patient: A Case Report. A A Pract. 2020 Feb 15;14(4):99-101 Authors: Zee H, Song SA, Sahani N, Macias AA, Song PC, Juang J Abstract Ventilation during microlaryngoscopy previously included jet ventilation, microlaryngeal endotracheal tubes, and extended apnea. Historically,...
Related Articles A modular architecture for articulatory synthesis from gestural specification. J Acoust Soc Am. 2019 12;146(6):4458 Authors: Alexander R, Sorensen T, Toutios A, Narayanan S Abstract This paper proposes a modular architecture for articulatory synthesis from a gestural specification comprising relatively simple models for the vocal tract, the glottis, aero-acoustics, and articulatory control. The vocal tract module combines a...
Related Articles Recent measurements with a synthetic two-layer model of the vocal folds and extension of Titze's surface wave model to a body-cover model. J Acoust Soc Am. 2019 12;146(6):EL502 Authors: Fulcher LP, Scherer RC Abstract The experiments of Mendelsohn and Zhang in 2011 (J. Acoust. Soc. Am. 130, 2961-2968) with six synthetic, two-layer models of the vocal folds were undertaken to better understand the role that the body layer plays...
Related Articles [Rib cartilage for laryngeal reconstruction in patients with chondrosarcoma]. Laryngorhinootologie. 2020 03;99(3):166-167 Authors: Baumann A, Graf S, Buchberger AMS, Storck K, Pickhard A PMID: 31914461 [PubMed - indexed for MEDLINE]
Related Articles Phonationstrauma. Laryngorhinootologie. 2020 02;99(2):83-84 Authors: PMID: 32023646 [PubMed - indexed for MEDLINE]
Related Articles Triological Best Practice: When Is Surgical Intervention Indicated for Vocal Fold Leukoplakia? Laryngoscope. 2020 06;130(6):1362-1363 Authors: Kim CM, Chhetri DK PMID: 32034947 [PubMed - indexed for MEDLINE]
Related Articles Medialisierungsthyroplastik: Effekt der Platzierung auf Phonation. Laryngorhinootologie. 2020 03;99(3):140-141 Authors: PMID: 32120435 [PubMed - indexed for MEDLINE]
Related Articles Vokalisatrophie. Laryngorhinootologie. 2020 03;99(3):142-143 Authors: PMID: 32120436 [PubMed - indexed for MEDLINE]
Related Articles Unraveling the molecular pathobiology of vocal fold systemic dehydration using an in vivo rabbit model. PLoS One. 2020;15(7):e0236348 Authors: Cannes do Nascimento N, Dos Santos AP, Sivasankar MP, Cox A Abstract Vocal folds are a viscoelastic multilayered structure responsible for voice production. Vocal fold epithelial damage may weaken the protection of deeper layers of lamina propria and thyroarytenoid muscle and impair...
Related Articles TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients. J Exp Clin Cancer Res. 2020 Sep 23;39(1):200 Authors: Sacconi A, Donzelli S, Pulito C, Ferrero S, Spinella F, Morrone A, Rigoni M, Pimpinelli F, Ensoli F, Sanguineti G, Pellini R, Agrawal N, Izumchenko E, Ciliberto G, Giannì A, Muti P, Strano S, Blandino G Abstract BACKGROUND: SARS-coronavirus-2 enters host cells through binding...
Related Articles Recurrent laryngeal nerve monitoring during totally robot-assisted Ivor Lewis esophagectomy. Langenbecks Arch Surg. 2020 Sep 24;: Authors: Staubitz JI, van der Sluis PC, Berlth F, Watzka F, Dette F, Läßig A, Lang H, Musholt TJ, Grimminger PP Abstract PURPOSE: The robot-assisted approach for Ivor Lewis esophagectomy offers an enlarged, three-dimensional overview of the intraoperative situs. The vagal nerve (VN) can easily be...
Related Articles Hyrtl's fissures in cochlear implant surgery. Cochlear Implants Int. 2020 Sep 23;:1-5 Authors: Xie C, Harris R Abstract This case study presents a rare anatomical anomaly complicating cochlear implantation in the form of patent periotic ducts and Hyrtl's (tympanomeningeal) fissures. Hyrtl's fissures are transient anatomical conduits which normally ossify by the 24th week of gestation. Their persistence may cause inadvertent...
Publication date: November 2020Source: International Immunopharmacology, Volume 88Author(s): Mohammad Esmaeil Amini, Navid Shomali, Arash Bakhshi, Somaye Rezaei, Maryam Hemmatzadeh, Ramin Hosseinzadeh, Solat Eslami, Farhad Babaie, Saeed Aslani, Shahram Torkamandi, Hamed Mohammadi
Publication date: Available online 24 September 2020Source: American Journal of Infection ControlAuthor(s): Mohammed A Alzunitan, Eli N Perencevich, Michael B Edmond
Publication date: Available online 24 September 2020Source: American Journal of Infection ControlAuthor(s): Ann Scheck McAlearney, Alice A. Gaughan, Matthew J. DePuccio, Sarah R. MacEwan, Courtney Hebert, Daniel M. Walker
Publication date: November 2020Source: Clinical Neurology and Neurosurgery, Volume 198Author(s): Shumin Chen, Dongchun Cai, Peichu Huang, Jichang Liu, Yuzhi Lai, Jianfeng He, Liang Zhou, Hao Sun
Publication date: November 2020Source: Clinical Neurology and Neurosurgery, Volume 198Author(s): George Umemoto, Shinsuke Fujioka, Hajime Arahata, Miki Kawazoe, Nobutaka Sakae, Naokazu Sasagasako, Hirokazu Furuya, Yoshio Tsuboi
Publication date: November 2020Source: Clinical Neurology and Neurosurgery, Volume 198Author(s): Rafael Martinez-Perez, Asterios Tsimpas, Jose Luis Cuevas, Ivan Perales, Oscar Jimenez, Tomas Poblete, Pablo Augusto Rubino, Jorge Mura
109 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: head and neck These pubmed results were generated on 2020/09/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
28 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/09/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Publication date: Available online 24 September 2020Source: Clinical TherapeuticsAuthor(s): Eunwoo Kim, Inyoung Hwang, SeungHwan Lee, Jaeseong Oh, Hyewon Chung, Myungwon Jin, Soon Ha Kim, Kyung-Sang Yu
Abstract Defense, vigilance, and optimal foraging are frequently related to the formation of flocks in birds. Few studies concerning long-distance migrant shorebirds analyzed whether phylogeny and ecological similarities of species are associated with the formation of heterospecific flocks. Here, we explore (1) the niche conservatism theory, (2) the competition-relatedness hypothesis, and (3) the niche construction hypothesis to explain the formation of wintering Nearctic-Neotropical...
Abstract Background Dental caries of deciduous teeth (Early Childhood Caries, ECC) has become a crucial oral health problem over the decades in China. The aim of this study was to examine the prevalence and severity of ECC among preschool children from Guangdong Province, Southern China. In addition, to assess the association of ECC with reported oral health-related behaviors. ...
Abstract Objectives The present study analyzed the association between (i) eating habits during pregnancy, (ii) advice from family or friends about gestational weight gain (GWG), and iii) personal effort to stay within weight gain limits, and meeting GWG recommendations. Methods Participants included pregnant and postpartum women who completed the...
Related Articles A rare case of cardiac tamponade masquerading as acute abdomen. Int J Surg Case Rep. 2020 Sep 03;: Authors: Maffione F, Romano L, Di Sibio A, Brandolin D, Schietroma M, Carlei F, Giuliani A Abstract INTRODUCTION: Acute abdomen is any acute abdominal condition requiring a quick response. The incidence varies according to age and disease aetiology. The abdominal discomfort associated with extra-abdominal pathophysiology and thoracic...
Related Articles Complete resection of rectal cancer with a synchronous solitary adrenal metastasis: A case report. Int J Surg Case Rep. 2020 Sep 16;75:242-245 Authors: Hayashi H, Murase Y, Sano H, Nishio K, Kumazawa I Abstract INTRODUCTION: Solitary adrenal metastasis derived from colorectal cancer is rare. Adrenal metastasis is usually associated with systemic spread of the disease and is considered to be unsuitable for surgical resection....
Related Articles Potential risk of impertinent administration of methylprednisolone in lumbar spine surgery: A case report. Int J Surg Case Rep. 2020 Sep 14;75:246-251 Authors: Xie LL, Zhu J, Chen XD, Yang CY, Yan ZL, Dan P Abstract INTRODUCTION: Several complications of intravenous administration of Methylprednisolone in spine surgery have been reported previously. However, perioperative Addisonian crisis resulting from postoperative routine...
Related Articles Achalasia in a woman presenting with vitiligo: A case report. Int J Surg Case Rep. 2020 Sep 14;75:252-257 Authors: Suprapto B, Aswin A Abstract BACKGROUND: Achalasia is a rare motor disorder of the oesophagus that typically characterized by the absence of oesophagus peristalsis and failure of swallow induced relaxation of oesophagus sphincter (LOS). The prevalence of achalasia is eight cases per million population. ...
Related Articles Current developments in the combination therapy of relapsed/refractory multiple myeloma. Expert Rev Anticancer Ther. 2020 Sep 24;: Authors: Maples KT, Joseph NS, Harvey RD Abstract INTRODUCTION: Therapy for patients with multiple myeloma has improved dramatically over the past decade following the introduction of novel agents and combinations across the disease spectrum. When relapse or refractory disease develops, non-cross-resistant...
Related Articles Dupilumab as Add-on Therapy for Chronic Rhinosinusitis With Nasal Polyposis in Aspirin Exacerbated Respiratory Disease. Am J Rhinol Allergy. 2020 Sep 23;:1945892420961969 Authors: Mustafa SS, Vadamalai K, Scott B, Ramsey A Abstract BACKGROUND: Aspirin-exacerbated respiratory disease (AERD) affects 7% of asthmatics. Usual therapies are inadequate for asthma and/or nasal polyposis, leading to decreased quality of life. ...
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