Δευτέρα 28 Σεπτεμβρίου 2020

 

Small bowel obstruction after caesarean section: Laparoscopic management. Two case report.
Related Articles Small bowel obstruction after caesarean section: Laparoscopic management. Two case report. Int J Surg Case Rep. 2020 Sep 14;: Authors: Di Buono G, Ricupati F, Maienza E, Gulotta L, Buscemi S, Agrusa A Abstract INTRODUCTION: Caesarean section is the most common abdominal surgery performed on women worldwide. Adhesions represent a severe complication of cesarean section and can cause different degrees of bowel obstruction. ...
pubmed: "int j surg case rep...
Sat Sep 26, 2020 14:51
Difficulties in diagnosing the alveolar echinococcosis (case report).
Related Articles Difficulties in diagnosing the alveolar echinococcosis (case report). Int J Surg Case Rep. 2020 Aug 31;75:258-260 Authors: Kaliyeva D, Yukhnevich Y, Abatov N, Nurbekov A Abstract INTRODUCTION: Alveolar echinococcosis is dangerous parasitic zoonose with the large endemic area. This disease has a high prevalence in Kazakhstan. PRESENTATION OF CASE: We report on a 45-year woman suffering from alveolar echinococcosis with...
pubmed: "int j surg case rep...
Sat Sep 26, 2020 14:51
Cholecystitis with abdominal wall biloma after percutaneous transhepatic gallbladder aspiration: A case report.
Related Articles Cholecystitis with abdominal wall biloma after percutaneous transhepatic gallbladder aspiration: A case report. Int J Surg Case Rep. 2020 Sep 18;75:276-278 Authors: Toritani K, Sugita M, Shimizu A, Watanabe A, Ono HA, Baba H Abstract BACKGROUND: Abdominal wall biloma is an uncommon entity. We herein report an extremely rare case of cholecystitis with abdominal wall biloma after percutaneous transhepatic gallbladder aspiration...
pubmed: "int j surg case rep...
Sat Sep 26, 2020 14:51
Systematic rapid living review on rehabilitation needs due to COVID-19: update to May 31st, 2020.
Related Articles Systematic rapid living review on rehabilitation needs due to COVID-19: update to May 31st, 2020. Eur J Phys Rehabil Med. 2020 Aug;56(4):508-514 Authors: Andrenelli E, Negrini F, de Sire A, Arienti C, Patrini M, Negrini S, Ceravolo MG, International Multiprofessional Steering Committee of Cochrane Rehabilitation REH-COVER action Abstract INTRODUCTION: This paper adds to the series of systematic rapid living reviews, started...
International Journal of Experimental Dental Science
Sat Sep 26, 2020 14:51
A Targeted Molecular Localization Imaging Method Applied to Tumor Microvasculature
Objectives Ultrasound contrast agents, consisting of gas-filled microbubbles (MBs), have been imaged using several techniques that include ultrasound localization microscopy and targeted molecular imaging. Each of these techniques aims to provide indicators of the disease state but has traditionally been performed independently without co-localization of molecular markers and super-resolved vessels. In this article, we present a new imaging technology: a targeted molecular localization (TML)...
Investigative Radiology - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Transcranial magnetic stimulation and magnetic resonance spectroscopy: opportunities for a bimodal approach in human neuroscience
Publication date: Available online 26 September 2020Source: NeuroImageAuthor(s): Koen Cuypers, Anouk Marsman
NeuroImage
Sat Sep 26, 2020 14:52
Can This Be Healed, Doctor? Perspectives on Capacity, Chronic Mental Illness, and Practicing Compassionate Medicine.
Related Articles Can This Be Healed, Doctor? Perspectives on Capacity, Chronic Mental Illness, and Practicing Compassionate Medicine. Mil Med. 2020 Mar 02;185(3-4):323-324 Authors: Horch M, Scott J, Hesdorffer C, Logan J PMID: 32976582 [PubMed - as supplied by publisher]
Association of Military Surgeons of the United States
Sat Sep 26, 2020 14:54
Adverse Childhood Experience, Genes, and PTSD Risk in Soldiers: A Methylation Study.
Related Articles Adverse Childhood Experience, Genes, and PTSD Risk in Soldiers: A Methylation Study. Mil Med. 2020 Mar 02;185(3-4):377-384 Authors: Hossack MR, Reid MW, Aden JK, Gibbons T, Noe JC, Willis AM Abstract INTRODUCTION: Epigenetics can serve as a marker of susceptibility to many known psychiatric diseases. DNA methylation patterns of multiple genes have been studied in both civilian populations and military personnel with post-traumatic...
Association of Military Surgeons of the United States
Sat Sep 26, 2020 14:54
Initial displacement as a risk factor for avascular necrosis of the femoral head in pediatric femoral neck fractures: a review of one hundred eight cases.
Related Articles Initial displacement as a risk factor for avascular necrosis of the femoral head in pediatric femoral neck fractures: a review of one hundred eight cases. Int Orthop. 2020 01;44(1):129-139 Authors: Wang W, Li Y, Guo Y, Li M, Mei H, Shao J, Xiong Z, Li J, Canavese F, Chen S, Chinese Multicenter Pediatric Orthopedic Study Group (CMPOS) Abstract PURPOSE: To evaluate the correlation between avascular necrosis (AVN) and the amount...
Technologies in Treatment of Head & Neck
Sat Sep 26, 2020 14:56
Pediatric tracheotomy in infants: Based on 10 years of experience at a pediatric tertiary center in South Korea.
Related Articles Pediatric tracheotomy in infants: Based on 10 years of experience at a pediatric tertiary center in South Korea. Asian J Surg. 2020 Apr;43(4):567-568 Authors: Sung ES, Lee IW, Roh HJ, Lee JC PMID: 31952878 [PubMed - indexed for MEDLINE]
Technologies in Treatment of Head & Neck
Sat Sep 26, 2020 14:56
Development of a Tongue Immobilization Device Using a 3D Printer for IMRT of Nasopharyngeal Cancer Patients.
Related Articles Development of a Tongue Immobilization Device Using a 3D Printer for IMRT of Nasopharyngeal Cancer Patients. Cancer Res Treat. 2020 Sep 15;: Authors: Ju SG, Ahn YC, Kim YB, Park SG, Choi YM, Na CH, Hong CS, Oh D, Kwon DY, Kim CC, Kim DH Abstract Purpose: This study aimed to reduce radiation doses to the tongue, a patient-specific semi-customized tongue immobilization device (SCTID) was developed using a 3D printer for helical...
Technologies in Treatment of Head & Neck
Sat Sep 26, 2020 14:56
Sumatriptan alleviates radiation-induced oral mucositis in rats by inhibition of NF-kB and ERK activation, prevention of TNF-α and ROS release.
Related Articles Sumatriptan alleviates radiation-induced oral mucositis in rats by inhibition of NF-kB and ERK activation, prevention of TNF-α and ROS release. Arch Oral Biol. 2020 Sep 16;119:104919 Authors: Ala M, Mohammad Jafari R, Ala M, Agbele AT, Hejazi SM, Tavangar SM, Mahdavi SRM, Dehpour AR Abstract OBJECTIVES: Oral mucositis caused by radiation therapy is a common problem in cancer patients, especially those with head and neck cancer....
Technologies in Treatment of Head & Neck
Sat Sep 26, 2020 14:56
Applications of Electrospinning for Tissue Engineering in Otolaryngology.
Related Articles Applications of Electrospinning for Tissue Engineering in Otolaryngology. Ann Otol Rhinol Laryngol. 2020 Sep 25;:3489420959692 Authors: Heilingoetter A, Smith S, Malhotra P, Johnson J, Chiang T Abstract OBJECTIVE: In tissue engineering, biomaterials create a 3D scaffold for cell-to-cell adhesion, proliferation and tissue formation. Because of their similarity to extracellular matrix and architectural adaptability, nanofibers...
otol rhinol
Sat Sep 26, 2020 15:02
Small ceramide tames big p53 mutant beast.
Related Articles Small ceramide tames big p53 mutant beast. Oncotarget. 2020 Sep 15;11(37):3418-3419 Authors: Hill RA, Liu Z, Liu YY PMID: 32973966 [PubMed]
Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/
Sat Sep 26, 2020 15:12
SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women.
Related Articles SNPs in the interleukin-12 signaling pathway are associated with breast cancer risk in Puerto Rican women. Oncotarget. 2020 Sep 15;11(37):3420-3431 Authors: Núñez-Marrero A, Arroyo N, Godoy L, Rahman MZ, Matta JL, Dutil J Abstract Interleukin-12 (IL-12) is a proinflammatory cytokine that links innate and adaptive immune responses against tumor cells. Single Nucleotide Polymorphisms (SNPs) in IL-12 genes have been associated...
Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/
Sat Sep 26, 2020 15:12
ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest.
Related Articles ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest. Oncotarget. 2020 Sep 15;11(37):3432-3442 Authors: Scotto L, Serrano XJ, Zullo K, Kinahan C, Deng C, Sawas A, Bates S, O'Connor OA Abstract The antiproliferative effect induced by histone deactylase inhibitors (HDACi) is associated with the up-regulated expression of the cyclin-dependent kinase inhibitor p21....
Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/
Sat Sep 26, 2020 15:12
Novel combination therapy for melanoma induces apoptosis via a gap junction positive feedback mechanism.
Related Articles Novel combination therapy for melanoma induces apoptosis via a gap junction positive feedback mechanism. Oncotarget. 2020 Sep 15;11(37):3443-3458 Authors: Bagati A, Hutcherson TC, Koch Z, Pechette J, Dianat H, Higley C, Chiu L, Song Y, Shah J, Chazen E, Nicolais A, Casey P, Thompson K, Burke K, Nikiforov MA, Zirnheld J, Zucker SN Abstract Metastatic melanoma cells overexpressing gap junctions were assayed for their ability...
Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/
Sat Sep 26, 2020 15:12
Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma.
Related Articles Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma. Oncotarget. 2020 Sep 15;11(37):3459-3472 Authors: Marengo B, Meta E, Brullo C, De Ciucis C, Colla R, Speciale A, Garbarino O, Bruno O, Domenicotti C Abstract Pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea compounds (STIRUR 13, STIRUR 41 and BUR 12) have been demonstrated...
Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/
Sat Sep 26, 2020 15:12
Expression of Glioma-associated oncogene homolog 1 as biomarker with sonidegib in advanced basal cell carcinoma.
Related Articles Expression of Glioma-associated oncogene homolog 1 as biomarker with sonidegib in advanced basal cell carcinoma. Oncotarget. 2020 Sep 15;11(37):3473-3483 Authors: Dummer R, Liu L, Squittieri N, Gutzmer R, Lear J Abstract The pivotal BOLT (Basal cell carcinoma Outcomes with LDE225 [sonidegib] Treatment) study established the durable efficacy and manageable toxicity of sonidegib 200 mg once daily (QD) through 42 months in...
Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/
Sat Sep 26, 2020 15:12
Correction: Improved anti-tumor efficacy via combination of oxaliplatin and fibrin glue in colorectal cancer.
Related Articles Correction: Improved anti-tumor efficacy via combination of oxaliplatin and fibrin glue in colorectal cancer. Oncotarget. 2020 Sep 15;11(37):3484-3485 Authors: Hu Y, Yu T, Liu X, He Y, Deng L, Guo J, Hua Y, Luo T, Gao X Abstract [This corrects the article DOI: 10.18632/oncotarget.23507.]. PMID: 32973972 [PubMed]
Oncotarget,Albany, N.Y. : Impact Journals,http://www.impactjournals.com/oncotarget/
Sat Sep 26, 2020 15:12
A reliable strategy for single-cell RNA sequencing analysis using cryoconserved primary cortical cells
Publication date: Available online 25 September 2020Source: Journal of Neuroscience MethodsAuthor(s): Lucia Verrillo, Eleonora Mangano, Denise Drongitis, Ivan Merelli, Francesca Pischedda, Giovanni Piccoli, Clarissa Consolandi, Roberta Bordoni, Maria Giuseppina Miano
Journal of Neuroscience Methods
Sat Sep 26, 2020 15:13
Circular RNA 0086996 regulates growth and migration of osteosarcoma cells via miR-125b-5p
Publication date: Available online 25 September 2020Source: Pathology - Research and PracticeAuthor(s): Zhanpeng Luo, Yi Yang, Dawei Li, Long Yu, Ning Liu, Litao Li, Yuanzheng Ma
ScienceDirect Publication: Pathology - Research and Practice
Sat Sep 26, 2020 15:14
Psychiatric Comorbidities and Psychiatric Medication Use Are Highly Prevalent in Patients With Eosinophilic Esophagitis and Associate With Clinical Presentation.
Related Articles Psychiatric Comorbidities and Psychiatric Medication Use Are Highly Prevalent in Patients With Eosinophilic Esophagitis and Associate With Clinical Presentation. Am J Gastroenterol. 2020 06;115(6):853-858 Authors: Reed CC, Corder SR, Kim E, Sanders E, Tappata M, Eluri S, Dellon ES Abstract OBJECTIVES: The prevalence of psychiatric disease in patients with eosinophilic esophagitis (EoE) is not fully characterized. We aimed to...
pubmed: epilepsy treatment
Sat Sep 26, 2020 15:14
A Framework to Assess the Information Dynamics of Source EEG Activity and Its Application to Epileptic Brain Networks.
Related Articles A Framework to Assess the Information Dynamics of Source EEG Activity and Its Application to Epileptic Brain Networks. Brain Sci. 2020 Sep 22;10(9): Authors: Kotiuchyi I, Pernice R, Popov A, Faes L, Kharytonov V Abstract This study introduces a framework for the information-theoretic analysis of brain functional connectivity performed at the level of electroencephalogram (EEG) sources. The framework combines the use of common...
pubmed: epilepsy treatment
Sat Sep 26, 2020 15:14
Is it really a seizure? The challenge of paroxysmal non-epileptic events in young infants.
Related Articles Is it really a seizure? The challenge of paroxysmal non-epileptic events in young infants. Clin Exp Pediatr. 2020 Sep 18;: Authors: Jung SY, Kang JW Abstract Paroxysmal non-epileptic events (PNE) comprise of a variety of non-epileptic behaviors and are divided into various types. A more accurate diagnosis is possible by examining the video clip provided by the caregiver. In infants, physiologic PNE accounts for the majority...
pubmed: epilepsy treatment
Sat Sep 26, 2020 15:14
Implanted vagus nerve stimulation in 126 patients: surgical technique and complications.
Related Articles Implanted vagus nerve stimulation in 126 patients: surgical technique and complications. Rozhl Chir. 2020;99(7):304-310 Authors: Bláha M, Tichý M Abstract INTRODUCTION: Vagus nerve stimulation is a palliative treatment for patients with refractory epilepsy to reduce the frequency and intensity of seizures. A bipolar helical electrode is placed around the left vagus nerve at the cervical level and is connected to the pulse generator...
pubmed: epilepsy treatment
Sat Sep 26, 2020 15:14
An immunotherapy effect analysis in Rasmussen encephalitis.
Related Articles An immunotherapy effect analysis in Rasmussen encephalitis. BMC Neurol. 2020 Sep 24;20(1):359 Authors: Liba Z, Vaskova M, Zamecnik J, Kayserova J, Nohejlova H, Ebel M, Sanda J, Ramos-Rivera GA, Brozova K, Liby P, Tichy M, Krsek P Abstract BACKGROUND: Immune-mediated mechanisms substantially contribute to the Rasmussen encephalitis (RE) pathology, but for unknown reasons, immunotherapy is generally ineffective in patients who...
pubmed: epilepsy treatment
Sat Sep 26, 2020 15:14
Neurophysiological and Genetic Findings in Patients With Juvenile Myoclonic Epilepsy.
Related Articles Neurophysiological and Genetic Findings in Patients With Juvenile Myoclonic Epilepsy. Front Integr Neurosci. 2020;14:45 Authors: Stefani S, Kousiappa I, Nicolaou N, Papathanasiou ES, Oulas A, Fanis P, Neocleous V, Phylactou LA, Spyrou GM, Papacostas SS Abstract Objective: Transcranial magnetic stimulation (TMS), a non-invasive procedure, stimulates the cortex evaluating the central motor pathways. The response is called motor...
pubmed: epilepsy treatment
Sat Sep 26, 2020 15:14
Effect of Brivaracetam on Efficacy and Tolerability in Patients With Brain Tumor-Related Epilepsy: A Retrospective Multicenter Study.
Related Articles Effect of Brivaracetam on Efficacy and Tolerability in Patients With Brain Tumor-Related Epilepsy: A Retrospective Multicenter Study. Front Neurol. 2020;11:813 Authors: Maschio M, Maialetti A, Mocellini C, Domina E, Pauletto G, Costa C, Mascia A, Romoli M, Giannarelli D Abstract Background: Epilepsy is a common symptom of brain tumors and is often pharmacoresistent. Among new antiseizure medications (ASMs) Brivaracetam (BRV)...
pubmed: epilepsy treatment
Sat Sep 26, 2020 15:14
The Concept of an Epilepsy Brain Bank.
Related Articles The Concept of an Epilepsy Brain Bank. Front Neurol. 2020;11:833 Authors: Hernandez-Ronquillo L, Miranzadeh Mahabadi H, Moien-Afshari F, Wu A, Auer R, Zherebitskiy V, Borowsky R, Mickleborough M, Huntsman R, Vrbancic M, Cayabyab FS, Taghibiglou C, Carter A, Tellez-Zenteno JF Abstract Epilepsy comprises more than 40 clinical syndromes affecting millions of patients and families worldwide. To decode the molecular and pathological...
pubmed: epilepsy treatment
Sat Sep 26, 2020 15:14
Preoperative evaluation of dynamic contrast-enhanced MRI-guided lesion identification using morphometric and textural analysis for patients with epilepsy.
Related Articles Preoperative evaluation of dynamic contrast-enhanced MRI-guided lesion identification using morphometric and textural analysis for patients with epilepsy. Exp Ther Med. 2020 Nov;20(5):98 Authors: Feizhou D, Jing G, Peng W, Jialing W, Rui J Abstract Diagnosing epilepsy at the early stages is pivotal in the prevention and subsequent treatment of major epileptic events. MRI has been previously demonstrated to be beneficial in optimizing...
pubmed: epilepsy treatment
Sat Sep 26, 2020 15:14
Transient coating of γ-Fe2O3 nanoparticles with glutamate for its delivery to and removal from brain nerve terminals.
Related Articles Transient coating of γ-Fe2O3 nanoparticles with glutamate for its delivery to and removal from brain nerve terminals. Beilstein J Nanotechnol. 2020;11:1381-1393 Authors: Paliienko K, Pastukhov A, Babič M, Horák D, Vasylchenko O, Borisova T Abstract Glutamate is the main excitatory neurotransmitter in the central nervous system and excessive extracellular glutamate concentration is a characteristic feature of stroke, brain trauma,...
pubmed: epilepsy treatment
Sat Sep 26, 2020 15:14
Mortality implications and factors associated with nonengagement in a public epilepsy care initiative in a transient population.
Related Articles Mortality implications and factors associated with nonengagement in a public epilepsy care initiative in a transient population. Epilepsy Behav. 2020 Sep 22;112:107438 Authors: Chawla A, Singh G, Sharma S, Bansal R, Bansal N, Chowdhury A, Paul BS, Sharma S, Sander JW Abstract BACKGROUND: Community-based, public care programs are a requisite to close the epilepsy treatment gap in disadvantaged communities in low- and middle-income...
pubmed: epilepsy treatment
Sat Sep 26, 2020 15:14
Analyzing cadaveric erector spinae plane block: a compendious approach.
Related Articles Analyzing cadaveric erector spinae plane block: a compendious approach. Reg Anesth Pain Med. 2020 Sep 24;: Authors: Diwan S, Sala-Blanch X, Nair A, Shah D PMID: 32972918 [PubMed - as supplied by publisher]
anesth pain med
Sat Sep 26, 2020 15:19
Letter to the editor: head-mounted display for regional anesthesia.
Related Articles Letter to the editor: head-mounted display for regional anesthesia. Reg Anesth Pain Med. 2020 Sep 24;: Authors: Hughey S, Cole J, Booth G, Longwell J PMID: 32972919 [PubMed - as supplied by publisher]
anesth pain med
Sat Sep 26, 2020 15:19
Peripheral nerve blocks in children and adolescents with Ehlers-Danlos syndrome hypermobility type.
Related Articles Peripheral nerve blocks in children and adolescents with Ehlers-Danlos syndrome hypermobility type. Reg Anesth Pain Med. 2020 Sep 24;: Authors: Vecchione T, Waisel D, Boretsky K PMID: 32972920 [PubMed - as supplied by publisher]
anesth pain med
Sat Sep 26, 2020 15:19
High-grade B-Cell Lymphoma With MYC, BCL2, and/or BCL6 Translocations/Rearrangements: Clinicopathologic Features of 51 Cases in a Single Institution of South China
Double-hit/triple-hit lymphomas (DH/THLs) are high-grade B-cell lymphomas with MYC and BCL2 rearrangements and/or BCL6 rearrangements, which have poor outcomes after standard chemoimmunotherapy. This retrospective study analyzed 51 patients (range, 19 to 82 y) diagnosed from 2016 to 2019 and treated for DH/THL (n=34 MYC/BCL6 DHL, n=14 MYC/BCL2 DHL, n=3 THL) at one institution in South China. Extranodal lesions occurred in 32 patients (62.7%), more frequently in MYC/BCL6 DHL (22/34, 64.7%) than in...
The American Journal of Surgical Pathology - Published Ahead-of-Print
Fri Sep 25, 2020 03:00
Histopathologic Characterization of Mogamulizumab-associated Rash
Rash is one of the most common adverse events observed with mogamulizumab, an anti-C-C chemokine receptor 4 monoclonal antibody approved for previously treated mycosis fungoides (MF) and Sezary syndrome (SS). Given the nonspecific clinical presentations of this rash, histopathologic distinction from MF/SS is critical for informing clinical management. We performed a comprehensive characterization of the histopathologic findings in mogamulizumab-associated rash (MAR) with the integration of high-throughput...
The American Journal of Surgical Pathology - Published Ahead-of-Print
Fri Sep 25, 2020 03:00
Clinicopathologic Features of Chronic Intestinal Schistosomiasis and Its Distinction From Crohn Disease
Chronic intestinal schistosomiasis (CIS) can mimic chronic colitis of other etiologies, particularly inflammatory bowel disease. Recognizing clinical and pathologic features unique to schistosomiasis can facilitate differential diagnosis. Clinical, endoscopic, imaging, macroscopic, and histologic features of 40 CIS cases were reviewed and compared with 40 cases of Crohn disease (CD). The most common symptoms of CIS were abdominal pain, distention, bloody stool, weight loss, and anemia. Lesions were...
The American Journal of Surgical Pathology - Published Ahead-of-Print
Fri Sep 25, 2020 03:00
Hepatoid Teratoma, Hepatoid Yolk Sac Tumor, and Hepatocellular Carcinoma: A Morphologic and Immunohistochemical Study of 30 Cases
Rare hepatoid teratomas (HTs) in testicular germ cell tumor patients mimic hepatoid yolk sac tumor (HYST) and hepatocellular carcinoma (HCC). We compared the features of 2 metastatic HTs, 12 HYSTs, and 16 HCCs. The mean ages were 36, 40, and 62.5 years, respectively. The HTs formed sheets of hepatocyte-like cells with macrovesicular fat arranged in vague lobules with intervening fibrous bands containing biliary ductule–like structures and abortive portal triads. HTs lacked basement membrane deposits,...
The American Journal of Surgical Pathology - Published Ahead-of-Print
Fri Sep 25, 2020 03:00
Recurrent YAP1 and MAML2 Gene Rearrangements in Retiform and Composite Hemangioendothelioma
Retiform and composite hemangioendotheliomas (CHEs) are both locally aggressive, rarely metastasizing vascular neoplasms characterized by arborizing vascular channels lined by endothelial cells with a hobnail morphology. CHE displays additional cytologic and architectural components, including often vacuolated epithelioid cells, solid areas, or features reminiscent of well-differentiated angiosarcoma. Triggered by an index case of a soft tissue retiform hemangioendothelioma (RHE) which revealed a...
The American Journal of Surgical Pathology - Published Ahead-of-Print
Fri Sep 25, 2020 03:00
Clinicopathologic Study of Gleason Pattern 5 Prostatic Adenocarcinoma With “Single-cell” Growth Reveals 2 Distinct Types, One With “Plasmacytoid” Features
Each Gleason score category of prostatic adenocarcinoma (or Grade Group) may encompass a diverse group of architectural patterns such as well-formed glands, poorly formed glands, cribriform structures, single cells, and/or solid sheets. We have noted heterogeneity within the single-cell subtype of Gleason pattern 5 prostatic adenocarcinoma that has not been fully addressed. Therefore, we retrospectively reviewed a series of radical prostatectomies with high-grade prostatic adenocarcinoma (Grade Group...
The American Journal of Surgical Pathology - Published Ahead-of-Print
Fri Sep 25, 2020 03:00
FUS-NFATC2 or EWSR1-NFATC2 Fusions Are Present in a Large Proportion of Simple Bone Cysts
A simple bone cyst (SBC) is a benign bone lesion of unknown etiology. It can be differentiated from an aneurysmal bone cyst (ABC) by radiologic and histopathologic features, as well as by the absence of fusions of the USP6 gene characteristic of an ABC. In an attempt to differentiate between ABC and SBC in a recurrent bone cyst, we performed targeted RNA sequencing and found an EWSR1-NFATC2 fusion and no fusion of the USP6 gene. We subsequently analyzed additional 10 cysts, consistent with SBCs after...
The American Journal of Surgical Pathology - Published Ahead-of-Print
Fri Sep 25, 2020 03:00
Clinical evaluation of atlas- and deep learning-based automatic segmentation of multiple organs and clinical target volumes for breast cancer
Breast cancer is the most common cancer among women in many countries, accounting for 1 in 4 newly diagnosed cancers [1]. Moreover, it is the leading cause of cancer deaths in women in over 100 countries. As an integral part of the curative treatment for patients with breast cancer, the clinical utilization of radiation therapy (RT) has increased in recent decades. Thus, in this era of three-dimensional conformal and intensity-modulated RT, precise delineation of the clinical target volume (CTV)...
Radiotherapy and Oncology
Sat Sep 26, 2020 03:00
Indirubin exerts anticancer effects on human glioma cells by inducing apoptosis and autophagy
Glioma causes significant mortality across the world and the most aggressive type of brain cancer. The incidence of glioma is believed to increase in the next few decades and hence more efficient treatment str...
Applied and Industrial Microbiology
Fri Sep 25, 2020 03:00
New Horizons: Emerging Therapies and Targets in Thyroid Cancer.
Related Articles New Horizons: Emerging Therapies and Targets in Thyroid Cancer. J Clin Endocrinol Metab. 2020 Sep 25;: Authors: Ringel MD Abstract The treatment of patients with progressive metastatic follicular cell-derived and medullary thyroid cancers that do not respond to standard therapeutic modalities presents a therapeutic challenge. As a deeper understanding of the molecular drivers for these tumors has occurred and more potent and...
American Goiter Association
Sat Sep 26, 2020 15:28
Exploring Multiple Sclerosis (MS) and Amyotrophic Lateral Sclerosis (ALS) as neurodegenerative diseases and their treatments: A review.
Related Articles Exploring Multiple Sclerosis (MS) and Amyotrophic Lateral Sclerosis (ALS) as neurodegenerative diseases and their treatments: A review. Curr Top Med Chem. 2020 Sep 24;: Authors: Deeb O, Nabulsi M Abstract Growing concern about neurodegenerative diseases is becoming a global issue. It is estimated that not only their prevalence will increase but also morbidity and health burden will be really concerning. Scientists, researchers...
Current topics in medicinal chemistry
Sat Sep 26, 2020 15:31
Unveiling the potential of purinergic signaling in schistosomiasis treatment.
Related Articles Unveiling the potential of purinergic signaling in schistosomiasis treatment. Curr Top Med Chem. 2020 Sep 24;: Authors: Oliveira NF, Silva CLM Abstract Schistosomiasis is a neglected tropical disease. It is related to long-lasting granulomatous fibrosis and inflammation of target organs, and current sub-optimal pharmacological treatment awakens global public health concerns. Intravascular worms and eggs release antigens and...
Current topics in medicinal chemistry
Sat Sep 26, 2020 15:31
Discovery and Development of Inflammatory Inhibitors From 2-Phenylchromonone (Flavone) Scaffolds.
Related Articles Discovery and Development of Inflammatory Inhibitors From 2-Phenylchromonone (Flavone) Scaffolds. Curr Top Med Chem. 2020 Sep 24;: Authors: Xu C, Fang MY, Wang K, Liu J, Tai GP, Zhang ZT, Ruan BF Abstract Flavonoids are compounds based on the 2-phenylchromonone scaffold. Flavonoids can be divided into flavonoids, flavonols, dihydroflavones, anthocyanins, chalcones and diflavones according to the oxidation degree of the central...
Current topics in medicinal chemistry
Sat Sep 26, 2020 15:31
Cell kinetic markers in cutaneous squamous and basal cell carcinoma of the head and neck.
Related Articles Cell kinetic markers in cutaneous squamous and basal cell carcinoma of the head and neck. Braz J Otorhinolaryngol. 2020 Sep 12;: Authors: Alaeddini M, Etemad-Moghadam S Abstract INTRODUCTION: Proliferation markers play a significant role in the biologic behavior of tumors. Geminin is a known inhibitor of the cell cycle and DNA replication and has not been previously reported in cutaneous basal and squamous cell carcinomas of...
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial
Sat Sep 26, 2020 15:36
Characterization of BRAF mutation in patients older than 45 years with well-differentiated thyroid carcinoma.
Related Articles Characterization of BRAF mutation in patients older than 45 years with well-differentiated thyroid carcinoma. Braz J Otorhinolaryngol. 2020 Sep 12;: Authors: Barreno LRQ, Mello JBH, Barros-Filho MC, Francisco AL, Chulam TC, Pinto CAL, Gonçalves-Filho J, Kowalski LP Abstract INTRODUCTION: Papillary thyroid carcinoma is the most frequent endocrine neoplasia and its incidence has tripled over the past 35 years. Although papillary...
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial
Sat Sep 26, 2020 15:36
Titanium prostheses versus stapes columella type 3 tympanoplasty: a comparative prospective study.
Related Articles Titanium prostheses versus stapes columella type 3 tympanoplasty: a comparative prospective study. Braz J Otorhinolaryngol. 2020 Sep 14;: Authors: Bahmad F, Perdigão AG Abstract INTRODUCTION: Tympanoplasty is a surgical procedure designed to reconstruct the mechanisms of sound transmission in the middle ear. OBJECTIVE: Analyze, from an audiological point of view, patients with chronic otitis media undergoing type 3...
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial
Sat Sep 26, 2020 15:36
Norcantharidin: research advances in pharmaceutical activities and derivatives in recent years
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Jianbo Zhou, Yali Ren, Lu Tan, Xiaominting Song, Miao Wang, Yuzhi Li, Zhixing Cao, Chuanjie Guo
Biomedicine & Pharmacotherapy
Sat Sep 26, 2020 15:37
New insights into long non-coding RNAs in non-small cell lung cancer
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Ruifang Ye, Ruixiang Tang, Siyuan Gan, Rujia Li, Ying Cheng, Linlang Guo, Chao Zeng, Yanqin Sun
Biomedicine & Pharmacotherapy
Sat Sep 26, 2020 15:37
Recent advances in fructose intake and risk of hyperuricemia
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Congwang Zhang, Lijun Li, Yipeng Zhang, Changchun Zeng
Biomedicine & Pharmacotherapy
Sat Sep 26, 2020 15:37
Prolyl oligopeptidase inhibition by KYP-2407 increases alpha-synuclein fibril degradation in neuron-like cells
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Jinar Rostami, Maria Jäntti, Hengjing Cui, Maiju K. Rinne, Jyrki P. Kukkonen, Anna Falk, Anna Erlandsson, Timo Myöhänen
Biomedicine & Pharmacotherapy
Sat Sep 26, 2020 15:37
Structural characterization, hypoglycemic effects and antidiabetic mechanism of a novel polysaccharides from <em>Polygonatum kingianum</em> Coll. et Hemsl
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Ruoshi Li, Aien Tao, Runmei Yang, Min Fan, Xiaocan Zhang, Zefei Du, Feineng Shang, Conglong Xia, Baozhong Duan
Biomedicine & Pharmacotherapy
Sat Sep 26, 2020 15:37
Protective effect and mechanism of Qishiwei Zhenzhu pills on cerebral ischemia-reperfusion injury via blood-brain barrier and metabonomics
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Min Xu, Ruixia Wu, Yuan Liang, Ke Fu, You Zhou, Xiaoli Li, Lei Wu, Zhang Wang
Biomedicine & Pharmacotherapy
Sat Sep 26, 2020 15:37
Activation of Piezo1 by ultrasonic stimulation and its effect on the permeability of human umbilical vein endothelial cells
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Liguo Zhang, Xiaojie Liu, Lu Gao, Yun Ji, Lulu Wang, Can Zhang, Liping Dai, Jingjing Liu, Zhenyu Ji
Biomedicine & Pharmacotherapy
Sat Sep 26, 2020 15:37
<em>In vitro</em> and <em>in vivo</em> antimicrobial activities of a novel piperazine-containing benzothiazinones candidate TZY-5-84 against <em>Mycobacterium tuberculosis</em>
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Shaochen Guo, Lei Fu, Bin Wang, Xi Chen, Jiaojie Zhao, Mingliang Liu, Yu Lu
Biomedicine & Pharmacotherapy
Sat Sep 26, 2020 15:37
TB47 and clofazimine form a highly synergistic sterilizing block in a second-line regimen for tuberculosis in mice
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Wei Yu, Gift Chiwala, Yamin Gao, Zhiyong Liu, Sanjeep Sapkota, Zhili Lu, Lingmin Guo, Shahzad Akbar Khan, Nanshan Zhong, Tianyu Zhang
Biomedicine & Pharmacotherapy
Sat Sep 26, 2020 15:37
Nosocomial COVID-19 Infection and Severe COVID-19 Pneumonia in Patients Hospitalized for Alcoholic Liver Disease: A Case Report.
Related Articles Nosocomial COVID-19 Infection and Severe COVID-19 Pneumonia in Patients Hospitalized for Alcoholic Liver Disease: A Case Report. Am J Case Rep. 2020 Sep 25;21:e927452 Authors: Wiśniewska H, Skowron M, Bander D, Hornung M, Jurczyk K, Karpińska E, Laurans Ł, Socha Ł, Czajkowski Z, Wawrzynowicz-Syczewska M Abstract BACKGROUND COVID-19 is an infectious disease caused by SARS-CoV-2. It has spread rapidly through the world, endangering...
pubmed: "am j case rep"[jour...
Sat Sep 26, 2020 15:41
Difficult Diagnosis and Surgical Procedure for Scirrhous Gastric Cancer Complicated by Upside-Down Stomach: A Case Report.
Related Articles Difficult Diagnosis and Surgical Procedure for Scirrhous Gastric Cancer Complicated by Upside-Down Stomach: A Case Report. Am J Case Rep. 2020 Sep 25;21:e926002 Authors: Nakamoto H, Yokota R, Namba H, Ishikawa T, Yamada K, Hosoda M, Taguchi K Abstract BACKGROUND The upper stomach can be involved in 1 type of esophageal hiatal hernia in which the degree of stomach insertion is considerable and accompanied by a twist in the shaft...
pubmed: "am j case rep"[jour...
Sat Sep 26, 2020 15:41
Evaluating the effect of oral clarithromycin on acute cutaneous leishmaniasis lesions compared with systemic glucantime.
Related Articles Evaluating the effect of oral clarithromycin on acute cutaneous leishmaniasis lesions compared with systemic glucantime. J Dermatolog Treat. 2020 Sep 24;:1-6 Authors: Zabolinejad N, Layegh P, Abbasi Shaye Z, Salehi M, Ghanizadeh S Abstract BACKGROUND AND AIM: It is widely accepted that the high prevalence of leishmaniasis, demands the search for a tolerable effective treatment with the least side effects. This study aimed to...
Journal of Dermatological Treatment
Sat Sep 26, 2020 15:41
Microsurgical anatomy of the inferior intercavernous sinus.
Related Articles Microsurgical anatomy of the inferior intercavernous sinus. Surg Radiol Anat. 2020 Sep 25;: Authors: Chenin L, Toussaint P, Lefranc M, Havet E, Peltier J Abstract PURPOSE: Intercavernous sinuses (ICSs) are physiological communications between the cavernous sinuses. The ICSs run between the endosteal and meningeal layers of the dura mater of the sella turcica. Whereas the anterior and posterior ICSs have been frequently...
radiol anat
Sat Sep 26, 2020 15:42
Increased expression of CX3CL1 and CX3CR1 in papillary thyroid carcinoma.
Related Articles Increased expression of CX3CL1 and CX3CR1 in papillary thyroid carcinoma. Histol Histopathol. 2020 Sep 25;:18265 Authors: Wu W, Ren F, Guo M, Yang J, Xiao Y, Liu W Abstract CX3CL1 and its receptor CX3CR1 axis are involved in the development, progression and metastasis of many types of cancers. It has been reported that CX3CL1 and CX3CR1 expression was upregulated in some solid tumors. However, their roles in thyroid cancer remain...
Cellular and Molecular Biology
Sat Sep 26, 2020 15:44
A study of impairments in oculopharyngeal muscular dystrophy.
Related Articles A study of impairments in oculopharyngeal muscular dystrophy. Muscle Nerve. 2020 08;62(2):201-207 Authors: Brisson JD, Gagnon C, Brais B, Côté I, Mathieu J Abstract INTRODUCTION: In this study we aimed to document the prevalence and age of onset of motor impairments and other key symptoms in oculopharyngeal muscular dystrophy (OPMD). METHODS: Retrospective chart review of patients followed at the Saguenay Neuromuscular...
Dysphagia - Rehabilitation
Sat Sep 26, 2020 15:45
Comparison of Activation Patterns in Mirror Neurons and the Swallowing Network During Action Observation and Execution: A Task-Based fMRI Study.
Related Articles Comparison of Activation Patterns in Mirror Neurons and the Swallowing Network During Action Observation and Execution: A Task-Based fMRI Study. Front Neurosci. 2020;14:867 Authors: Jing YH, Lin T, Li WQ, Wu C, Li X, Ding Q, Wu MF, Xu GQ, Lan Y Abstract Background: Observation of a goal-directed motor action can excite the respective mirror neurons, and this is the theoretical basis for action observation (AO) as a novel tool...
Dysphagia - Rehabilitation
Sat Sep 26, 2020 15:45
[Bone Marrow Mesenchymal Stem Cell Exosomes Promote Brain Microvascular Endothelial Cell Proliferation and Migration in Rats].
Related Articles [Bone Marrow Mesenchymal Stem Cell Exosomes Promote Brain Microvascular Endothelial Cell Proliferation and Migration in Rats]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2020 Sep;51(5):599-604 Authors: Li XT, Zhao J, Xu DS, Zhang Y, Zhou ST Abstract Objective: To study the effect of bone marrow mesenchyml stem cell (BMSC) exosomes (Exo) on the proliferation and migration of brain microvascular endothelial cells in rats. Methods:...
Dysphagia - Rehabilitation
Sat Sep 26, 2020 15:45
Audiologic Outcome of Cochlear Implantation in Children With Cochlear Nerve Deficiency.
Related Articles Audiologic Outcome of Cochlear Implantation in Children With Cochlear Nerve Deficiency. Otol Neurotol. 2020 Sep 24;: Authors: Yousef M, Mesallam TA, Garadat SN, Almasaad A, Alzhrani F, Alsanosi A, Hagr A Abstract OBJECTIVE/HYPOTHESIS: The aim of this study was to investigate cochlear implantation (CI) outcome in children with nerve deficiency. STUDY DESIGN: Retrospective chart review. METHODS: A total of seven...
Dysphagia - Rehabilitation
Sat Sep 26, 2020 15:45
[Neuropsychiatric symptoms and caregivers' distress in anti-N-methyl-D-aspartate receptor encephalitis].
Related Articles [Neuropsychiatric symptoms and caregivers' distress in anti-N-methyl-D-aspartate receptor encephalitis]. Zhonghua Yi Xue Za Zhi. 2020 Sep 22;100(35):2758-2762 Authors: Wang QB, Guan HZ, Qiao M, Jiang Q, Fan SY, Ren HT, Zhou FC, He XX Abstract Objective: To explore the characteristics of psychiatric symptoms and caregivers' distress in anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis. Methods: Seventy-two patients with...
Zhonghua Yi Xue Za Zhi
Sat Sep 26, 2020 15:48
[Study on the precision of the robot-assisted sacroiliac screw placement].
Related Articles [Study on the precision of the robot-assisted sacroiliac screw placement]. Zhonghua Yi Xue Za Zhi. 2020 Sep 22;100(35):2763-2767 Authors: Zhao Y, Jiang CQ, Sun T, Xin DJ, Qu WQ, Wang ZH, Wang D, Zhang SD Abstract Objective: To evaluate the precision of the robot-assisted sacroiliac screw placement for posterior pelvis injury and the impacting factors. Methods: The clinical data of twenty-four cases of posterior pelvic fractures...
Zhonghua Yi Xue Za Zhi
Sat Sep 26, 2020 15:48
[Effects of percutaneous coronary intervention on cardiac function in ischemic cardiomyopathy patients with different left ventricular ejection fraction and SYNTAX score≤22].
Related Articles [Effects of percutaneous coronary intervention on cardiac function in ischemic cardiomyopathy patients with different left ventricular ejection fraction and SYNTAX score≤22]. Zhonghua Yi Xue Za Zhi. 2020 Sep 22;100(35):2768-2773 Authors: Zheng XF, Wu LM, Chen LL Abstract Objective: To evaluate the clinical impact of percutaneous coronary intervention (PCI) on left ventricular myocardial remodeling and main adverse cardiovascular...
Zhonghua Yi Xue Za Zhi
Sat Sep 26, 2020 15:48
[Effect of polyphyllin Ⅱ on the proliferation, invasion and chemosensitivity to temozolomide of glioma cells].
Related Articles [Effect of polyphyllin Ⅱ on the proliferation, invasion and chemosensitivity to temozolomide of glioma cells]. Zhonghua Yi Xue Za Zhi. 2020 Sep 22;100(35):2774-2778 Authors: Zhao YP, Duan WC, Wang YM, Zhang ZY, Liu XZ Abstract Objective: To investigate the effect and mechanism of Polyphyllin Ⅱ on the proliferation, invasion and chemosensitivity of glioma cells. Method: CCK-8 cell proliferation assays and Transwell assays were...
Zhonghua Yi Xue Za Zhi
Sat Sep 26, 2020 15:48
[Berberine protects myocardial injury and cardiac dysfunction in a septic rat model].
Related Articles [Berberine protects myocardial injury and cardiac dysfunction in a septic rat model]. Zhonghua Yi Xue Za Zhi. 2020 Sep 22;100(35):2779-2784 Authors: Jin JL, Zhang H, Liu Q, Jiang HH, Liu XX, Tang XZ Abstract Objectives: To investigated whether berberine could ameliorate septic cardiomyopathy in a rat model of sepsis and it's mechanisms. Methods: SD rats were divided into 3 groups: sepsis group (LPS group), rats were intraperitoneal...
Zhonghua Yi Xue Za Zhi
Sat Sep 26, 2020 15:48
[Protective effect and mechanism of mild hypothermia on liver injury after cardiopulmonary resuscitation in pigs].
Related Articles [Protective effect and mechanism of mild hypothermia on liver injury after cardiopulmonary resuscitation in pigs]. Zhonghua Yi Xue Za Zhi. 2020 Sep 22;100(35):2785-2790 Authors: Li YQ, Wang Y, Song J, Xie DY, Tang ZR, Li CS, Hao JY, Jing ML, Hu XM, Zhai JL, Liu ZX Abstract Objective: To investigate the effect of mild hypothermia therapy on liver after cardiopulmonary resuscitation. Methods: Thirty-three inbred Chinese Wuzhishan...
Zhonghua Yi Xue Za Zhi
Sat Sep 26, 2020 15:48
Cervical and ocular vestibular evoked myogenic potentials in determining nerve division involvement in patients with a tumor located in the internal auditory canal.
Related Articles Cervical and ocular vestibular evoked myogenic potentials in determining nerve division involvement in patients with a tumor located in the internal auditory canal. Auris Nasus Larynx. 2020 Sep 21;: Authors: Zwierzyńska K, Lachowska M, Sokołowski J, Niemczyk K Abstract OBJECTIVES: The study aimed at the analysis of the parameters of acoustic cervical and ocular vestibular evoked myogenic potentials (AC-cVEMP and AC-oVEMP)...
vestibular evoked
Sat Sep 26, 2020 15:51
Cervical Vestibular Evoked Myogenic Potentials in Idiopathic Intracranial Hypertension.
Related Articles Cervical Vestibular Evoked Myogenic Potentials in Idiopathic Intracranial Hypertension. J Clin Neurophysiol. 2020 Sep 22;: Authors: Uyaroğlu FG, Uçar R, Şengül G, Çelebisoy N Abstract PURPOSE: Idiopathic intracranial hypertension (IIH) is raised intracranial pressure without any identifiable etiology. The inner ear structures are susceptible to cerebrospinal fluid (CSF) pressure changes because of connections between the...
vestibular evoked
Sat Sep 26, 2020 15:51
"Exp Ther Med"[jour]; +17 new citations
17 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Exp Ther Med"[jour] These pubmed results were generated on 2020/09/26PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Experimental and therapeutic medicine
Sat Sep 26, 2020 15:55
Accuracy of Pulmonary Nodule Volumetry Using Noise-Optimized Virtual Monoenergetic Image and Nonlinear Blending Image Algorithms in Dual-Energy Computed Tomography: A Phantom Study
Objective The aim of the study was to assess accuracy of pulmonary nodule volumetry using noise-optimized virtual monoenergetic image (VMI+) and nonlinear blending image (NBI) algorithms in dual-energy computed tomography (DECT). Methods An anthropomorphic chest phantom with 10 simulated nodules (5 solid nodules and 5 ground-glass opacities) was scanned using DECT80/Sn140kV, DECT100/Sn140kV, and single-energy CT (SECT120kV/200mAs), respectively. The dual-energy images were reconstructed using...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Improved Computed Tomography Contrast Injection Rates Through Implantable Chest Power Ports
Objective The aim of this study was to optimize chest port contrast injections using stepwise improvements. Methods Ex vivo injections were tested. Two hundred scans using power port injections were then evaluated. Results The highest flow rate was achieved using a 19G access needle, larger diameter tubing, and warmed contrast. The mean injection rates in baseline and postimprovement groups were 2.7 ± 0.4 and 4.8 ± 0.4 mL/s, respectively (P
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Optimization of Contrast Agent Dosage on Contrast-Enhanced T2 Fluid-Attenuated Inversion Recovery: An In Vitro and In Vivo Study
Objective This study aimed to ascertain the minimum gadolinium dosage on contrast-enhanced (CE) T2 fluid-attenuated inversion recovery (FLAIR) at appropriate imaging time. Methods Different dosages of gadodiamide were imaged with a 3.0-T magnetic resonance scanner for T2-FLAIR and T1WI. Twenty glioma-induced rat models were randomly assigned into 4 groups (1/2, 1/4, 1/6, 1/8 of routine dosage) and imaged for T2-FLAIR and T1WI preinjection and postinjection of gadodiamide. Contrast-enhanced...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Cardiac Magnetic Resonance–Derived Indexed Volumes and Volume Ratios of the Cardiac Chambers Discriminating Group 2 Pulmonary Hypertension From Other World Health Organization Groups
Objective The aims of the study were to assess the performance of cardiac magnetic resonance (CMR)-derived cardiac chamber volumes and volume ratios to identify group 2 pulmonary hypertension (PH) patients and to determine their cutoff values with the highest sensitivity and specificity. Methods One hundred six patients underwent CMR, 2 months after the diagnosis of PH by right heart catheterization. We classified patients with pulmonary capillary wedge pressure of greater than 15 mm Hg as...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Prenatal and Postnatal Imaging Findings After Fetal Repair of Spinal Dysraphisms Using Cryopreserved Human Umbilical Cord Patch: A Case Series of 4 Patients
We describe a case series of imaging findings of 4 patients who underwent spinal dysraphisms repair in utero with novel patch material, cryopreserved human umbilical cord, in our institution. In our study, the prenatal and postnatal magnetic resonance imaging and ultrasound are reviewed and showed cord tethering and syrinx progression in all cases. Our report is the first description of magnetic resonance imaging and ultrasound findings in the context of using this novel patch in severe cases of...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Computed Tomography-Guided Biopsy for Small (≤20 mm) Lung Nodules: A Meta-Analysis
Purpose This study was designed to evaluate the diagnostic accuracy of computed tomography (CT)-guided biopsy for small lung nodules (SLNs) (≤20 mm) and to assess related complication rates. Methods We reviewed the Pubmed, Embase, and Cochrane Library databases to identify all relevant studies published as of April 2020. Random effects modeling were then used to evaluate pooled data pertaining to technical success rates, diagnostic accuracy, pneumothorax rates, and rates of hemoptysis. The...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Noncontrast Magnetic Resonance Angiography in the Era of Nephrogenic Systemic Fibrosis and Gadolinium Deposition
Gadolinium-based contrast agents for clinical magnetic resonance imaging are overall safe. However, the discovery of nephrogenic systemic fibrosis in patients with severe renal impairment and gadolinium deposition in patients receiving contrast have generated developments in contrast-free imaging of the vasculature, that is, noncontrast magnetic resonance angiography. This article presents an update on noncontrast magnetic resonance angiography techniques, with comparison to other imaging alternatives....
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Differentiation of Multiple Myeloma and Lytic Bone Metastases: Histogram Analysis
Objective Metastasis and multiple myeloma are common malignant bone marrow lesions. It may be difficult to distinguish because of similar imaging findings. The purpose of this study was to determine the value of histogram analysis on the computed tomography imaging. Methods Twenty-three patients with primary tumor and 23 patients with multiple myeloma were included in the study. All patients had lytic bone lesions on the thorax and abdominal computed tomography scan with contrast. Multiple...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Texture Analysis of Hepatocellular Carcinoma on Magnetic Resonance Imaging: Assessment for Performance in Predicting Histopathologic Grade
Objective The aim of the study was to evaluate the performance of texture analysis for discriminating the histopathological grade of hepatocellular carcinoma (HCC) on magnetic resonance imaging. Methods Preoperative magnetic resonance imaging data from 101 patients with HCC, including T2-weighted imaging, arterial phase, and apparent diffusion coefficient mapping, were analyzed using texture analysis software (TexRAD). Differences among the histological groups were analyzed using the Mann-Whitney...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Fat-Water Swaps in Iterative Decomposition of Water and Fat With Echo Asymmetry and Least-Squares Estimation Magnetic Resonance Imaging for Postinstrumentation Spine
Objective To determine the frequencies of fat-water swaps in iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) water-only images of the postinstrumentation spine and discuss the efficiency of in-phase imaging in improving visibility of the thecal sac. Materials and Methods A total of 276 patients (167 women; mean age, 62.3 years; range, 23–89 years) with metallic devices on the lumbar spine who received complete routine 1.5 T MR imaging, including...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
The Evaluation of Radiomic Models in Distinguishing Pilocytic Astrocytoma From Cystic Oligodendroglioma With Multiparametric MRI
Purpose To assess whether a machine-learning model based on texture features extracted from multiparametric magnetic resonance imaging could yield an accurate diagnosis in differentiating pilocytic astrocytoma from cystic oligodendrogliomas. Materials and Methods The preoperative images from multisequences were used for tumor segmentation. Radiomic features were extracted and selected for machine-learning models. Semantic features and selected radiomic features from training data set were...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Do Not Judge an Ossicle by Its Size: Type 1 Ossicles Associated With Posterior Tibial Tendon Dysfunction
Introduction Patients with type II navicular ossicles have traditionally been considered to be symptomatic, whereas patients with type I and III bones are considered asymptomatic without additional relevant imaging findings. The main objective of this study is to investigate the association of type I os naviculare with clinical symptomology and magnetic resonance imaging findings in comparison to types II and III ossicles. Methods Three hundred nine subjects with accessory navicular bone...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Evaluation of Spatial Resolution of Virtual Monochromatic Imaging In Vitro: Effect of Energy Level and Contrast
Objective Our aim was to evaluate effects of the energy level and contrast on the spatial resolution of virtual monochromatic imaging (VMI). Methods With 2 types of computed tomographic (CT) scanners (Discovery CT750 HD and Revolution CT), we scanned an elliptical cylinder acrylic phantom with 20- or 40-fold dilutions of contrast medium and obtained VMI data sets at 40, 50, 60, and 70 keV. We evaluated the effects of energy levels and contrast on modulation transfer function (MTF) and the...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Magnetic Resonance Imaging of Recurrent Adult Granulosa Cell Tumor of the Ovary: A Retrospective Analysis of 11 Cases
Objective The aim of the study was to characterize magnetic resonance imaging findings in patients with recurrent ovarian adult granulosa cell tumors (AGCTs). Methods Clinical and magnetic resonance imaging manifestations of recurrent AGCTs were evaluated in 11 patients. Results Initial recurrences of AGCT were diagnosed between 13 months and 30 years (mean, 11.3 years). Recurrent tumors were located in the pelvic peritoneum, the abdominal peritoneum, the retroperitoneum, and bone. The...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Detection of Shunting Into Pulmonary Artery on Multidetector Row Computed Tomography Arteriography Before Bronchial Arterial Embolization: A Preliminary Study
Objective The aim of this study was to investigate the diagnostic performance of detecting systemic arterial pulmonary circulation shunts on multidetector row computed tomography arteriography (MDCTA). Methods Thirty-five consecutive bronchial artery embolization sessions with preprocedural MDCTA were performed for 32 patients and 35 sessions. The MDCTA studies with computed tomography value of pulmonary trunk visually lower than that of ascending aorta were defined as “diagnostic MDCTA.”...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Hyperdense Thymic Atrophy After Chemotherapy in Pediatric Patients With Extrathoracic Malignancies
Objective The aim of the study was to evaluate computed tomography (CT) imaging findings of hyperdense thymic atrophy after chemotherapy in pediatric patients with extrathoracic malignancies. Methods Seventy-eight pediatric patients with extrathoracic malignancies, who developed thymic atrophy after chemotherapy, were included in this study. All patients underwent CT imaging before and after chemotherapy. We retrospectively reviewed the CT images. Hyperdense thymic atrophy was defined as...
Journal of Computer Assisted Tomography - Published Ahead-of-Print
Wed Sep 23, 2020 03:00
Repeat convection-enhanced delivery for diffuse intrinsic pontine glioma.
Related Articles Repeat convection-enhanced delivery for diffuse intrinsic pontine glioma. J Neurosurg Pediatr. 2020 Sep 25;:1-6 Authors: Bander ED, Ramos AD, Wembacher-Schroeder E, Ivasyk I, Thomson R, Morgenstern PF, Souweidane MM Abstract OBJECTIVE: While the safety and efficacy of convection-enhanced delivery (CED) have been studied in patients receiving single-dose drug infusions, agents for oncological therapy may require repeated or chronic...
Pediatric Neurosurgeons
Sat Sep 26, 2020 15:56
Mortality and complication management after surgery for colorectal cancer depending on the DKG minimum amounts for hospital volume
Publication date: Available online 25 September 2020Source: European Journal of Surgical OncologyAuthor(s): Johannes Diers, Philip Baum, Harald Matthes, Christoph-Thomas Germer, Armin Wiegering
European Journal of Surgical Oncology (EJSO)
Sat Sep 26, 2020 16:08
Simultaneous approach for patients with synchronous colon and rectal liver metastases: Impact of site of primary on postoperative and oncological outcomes
Publication date: Available online 25 September 2020Source: European Journal of Surgical OncologyAuthor(s): Simone Conci, Andrea Ruzzenente, Corrado Pedrazzani, Giulia Isa, Giulia Turri, Tommaso Campagnaro, Alessandro Valdegamberi, Fabio Bagante, Ivan Marchitelli, Alfredo Guglielmi
European Journal of Surgical Oncology (EJSO)
Sat Sep 26, 2020 16:08
Economic evaluation of adjuvant trastuzumab therapy for HER2-positive early-stage breast cancer: systematic review and quality assessment.
Related Articles Economic evaluation of adjuvant trastuzumab therapy for HER2-positive early-stage breast cancer: systematic review and quality assessment. Expert Rev Pharmacoecon Outcomes Res. 2020 Sep 24;:1-10 Authors: Genuino AJ, Gloria MAJ, Chaikledkaew U, Reungwetwattana T, Thakkinstian A Abstract INTRODUCTION: As the availability of new economic evaluations (EE) on adjuvant trastuzumab therapy for early-stage breast cancer (EBC) with HER2-positive...
pubmed: her2-positive breast...
Sat Sep 26, 2020 16:14

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