Drug Evaluation. Year 2018 Issue z1 is now available on CAOD.

In this issue: Expert Consensus Of Combined Oral Hypoglycemic Medication For Chinese Adult Type 2 Diabetes (中国成人2型糖尿病口服降糖药联合治疗专家共识) Chinese Society of Endocrinology ...... page:5-14,22 Enlightenment on Management and Medication from updated Foreign and Domestic Guideline and Expert Consensus on Diabetes (新近国内外糖尿病指南和共识对糖尿病管理理念和药物治疗选择带来的启示) MU Yiming ...... page:15-17 Based on Evidence-based and Expert Consensus: a Review of a New Insight on Oral Hypoglycemic Combination Therapy for Type 2 Diabetes Mellitus (基于循证和专家共识:谋求2型糖尿病口服降糖联合治疗新思路) LI Wen-juan, ,JI Qiu-he ...... page:18-22 Status of New oral Hypoglycemic Drugs for Type 2 Diabetes Mellitus (新型口服降糖药物在2型糖尿病治疗中的地位) GUO Li-xin ...... page:23-25,29 Seize the highly Opportunity Moment for Combined Oral Antidiabetic Drug (因时制宜,抓住2型糖尿病口服降糖药联合治疗的最佳"时间窗") LIU Zhe-long, ,YU Xue-feng ...... page:26-29 The Efficacy and Safety of the Oral Dual Antihyperglycemic Therapies Based on Metformin (以二甲双胍为基础的传统二联用药的疗效与安全性评价) Li Yan ...... page:30-34,47 Efficacy and safety of metformin combined with DPP-4 inhibitor (二甲双胍联合DPP-4抑制剂的临床疗效与安全性评价) XIAO Xin-hua ...... page:35-37,41 Cardiovascular Safety of DPP-4 Inhibitor Linagliptin: Focus and Interpretation of CARMELINA Study (DPP-4抑制剂利格列汀的心血管安全性——CARMELINA研究解读) JI Li-nong ...... page:38-41 Efficacy and Safety of Combination Therapy With Metformin and SGLT-2 inhibitor (二甲双胍与SGLT-2抑制剂联合治疗的临床疗效与安全性评价) FU Wei, ,HONG Tian-pei ...... page:42-47 Mechanisms of Cardiovascular benefits and Evidence with SGLT-2 inhibitors (SGLT-2抑制剂心血管获益的机制与临床证据) LI Xiao-ying ...... page:48-52 Antihyperglycemic Agent Therapy for Adult Patients with Type 2 Diabetes Mellitus 2017:a Position Statement of the Korean Diabetes Association (韩国糖尿病协会《成人2型糖尿病患者的抗高血糖药物治疗临床实践指南》解读) ZHANG Jin, ,LI Yan ...... page:53-56