The New England Journal of Medicine

CLINICAL DECISIONS Thyroid Function and Conception A.X. Chen, A.M. Leung, and T.I.M. Korevaar | N Engl J Med 2019;381:178-181 This interactive feature about a woman who has recently had a spontaneous miscarriage and tests positive for thyroid peroxidase antibodies offers a case vignette accompanied by essays that either support or discourage the use of levothyroxine to increase her chances of becoming pregnant. Read the opinions, share your comments, and vote at NEJM.org.

PERSPECTIVE A Most Reckless Proposal — A Plan to Continue Asbestos Use in the United States P.J. Landrigan and R.A. Lemen DOI: 10.1056/NEJMp1906207 | July 10, 2019 Mandatory Measles Vaccination in New York City — Reflections on a Bold Experiment J.D. Cantor N Engl J Med 2019;381:101-103 | Published Online June 5, 2019 Vaccination over Parental Objection — Should Adolescents Be Allowed to Consent to Receiving Vaccines? R.D. Silverman, D.J. Opel, and S.B. Omer N Engl J Med 2019;381:104-106 | Published Online June 5, 2019 Reforming the Orphan Drug Act for the 21st Century A. Sarpatwari and A.S. Kesselheim N Engl J Med 2019;381:106-108 Sister First, Doctor Second S. Sediqzadah N Engl J Med 2019;381:108-109 ORIGINAL ARTICLES C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations C.C. Butler and Others N Engl J Med 2019;381:111-120 Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer I.D. Davis and Others N Engl J Med 2019;381:121-131 | Published Online June 2, 2019 Trial of Galcanezumab in Prevention of Episodic Cluster Headache P.J. Goadsby and Others N Engl J Med 2019;381:132-141 Rimegepant, an Oral Calcitonin Gene–Related Peptide Receptor Antagonist, for Migraine R.B. Lipton and Others N Engl J Med 2019;381:142-149 A Multicenter Trial of Vena Cava Filters in Severely Injured Patients K.M. Ho and Others DOI: 10.1056/NEJMoa1806515 | July 7, 2019 SPECIAL ARTICLE Early Effects of an Accountable Care Organization Model for Underserved Areas M.J. Trombley and Others DOI: 10.1056/NEJMsa1816660 | July 10, 2019 CLINICAL PRACTICE Measles P.M. Strebel and W.A. Orenstein DOI: 10.1056/NEJMcp1905181 | July 10, 2019 REVIEW ARTICLE Hemolytic Transfusion Reactions S.R. Panch, C. Montemayor-Garcia, and H.G. Klein N Engl J Med 2019;381:150-162 Image Challenge What’s the diagnosis? Additional Published Content

IMAGES IN CLINICAL MEDICINE “Double Tongue” Appearance in Ludwig’s Angina I. Mohamad and M.S. Narayanan N Engl J Med 2019;381:163 Whooping Cough in a Young Infant D. Hillier N Engl J Med 2019;381:e4 CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL Case 21-2019: A 31-Year-Old Woman with Vision Loss M. Matiello, A.F. Juliano, M. Bowley, and A. Karaa N Engl J Med 2019;381:164-172 EDITORIALS COPD Exacerbations — A Target for Antibiotic Stewardship A.S. Brett and M.N. Al-Hasan N Engl J Med 2019;381:174-175 Improving Treatment for Advanced Prostate Cancer I.F. Tannock N Engl J Med 2019;381:176-177 CLINICAL DECISIONS Thyroid Function and Conception A.X. Chen, A.M. Leung, and T.I.M. Korevaar N Engl J Med 2019;381:178-181 MEDICINE AND SOCIETY Mistrust in Science — A Threat to the Patient–Physician Relationship R.J. Baron and A.J. Berinsky N Engl J Med 2019;381:182-185 CORRESPONDENCE Mass Drug Administration for Scabies — 2 Years of Follow-up Published Online June 26, 2019 Coronary Angiography after Cardiac Arrest without ST-Segment Elevation Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception Andexanet Alfa for Bleeding with Factor Xa Inhibitors Public–Private Partnerships in Global Health CORRECTIONS Pharmacologic Research in Pregnant Women — Time to Get It Right National Longitudinal Lesbian Family Study — Mental Health of Adult Offspring