Publication date: Available online 20 July 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Justin GreiweAbstractAs technology improves and telehealth companies continue to innovate, the ways in which physicians can provide care for their patients is constantly expanding. Providing quality healthcare is no longer constrained by local commutes and a brick and mortar footprint, but instead can be provided at a local, regional and national level in ways that were not...
Publication date: Available online 20 July 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Pengxiang Li, Abhishek Kavati, Justin T. Puckett, Jordan Jahnke, Paula Busse, Nicola A. Hanania, Benjamin Ortiz, Jalpa A. DoshiAbstractBackgroundAsthma in older adults is associated with high rates of morbidity and mortality; similarly, asthma can be severe enough among younger adults to warrant disability benefits. Reasons for poor outcomes in both groups of patients may include...
Abstract Background Early introduction of food allergens into children's diet is considered as a strategy for the prevention of food allergy. The major fish allergen parvalbumin exhibits high stability against gastrointestinal digestion. We investigated, if resistance of carp parvalbumin to digestion affects oral tolerance induction. Methods Natural Cyp c 1, nCyp c 1, and a gastrointestinal digestion‐sensitive recombinant Cyp c 1 mutant, mCyp c 1, were analyzed for their ability to induce...
Abstract Background Ragweed frequently causes seasonal allergies in North America and Europe. In the US, several related ragweed species with diverse geographical distribution cause allergic symptoms. Cross‐reactivity towards related ragweed species of IgE and treatment‐induced IgG4 has been demonstrated previously. However, less is known about the underlying T‐cell cross‐reactivity. Methods The allergen content of ragweed extracts was determined by mass spectrometry and related to T‐cell...
Abstract Asthma is a heterogeneous chronic syndrome which represents a relevant socioeconomic burden in both adults and children. Global asthma prevalence has been reported to be of approximately 300 million people, with an estimate of increasing figures up to 400 million by 20251. Among the identified distinct phenotypes and endotypes2, allergic asthma represents one of the most well‐characterized and relevant nosologic entity, with atopy playing a key role in the disease risk, onset and progression....
Abstract Food allergy is a major public health concern with avoidance of the trigger food(s) being central to management by the patient. Food information legislation mandates the declaration of allergenic ingredients; however, the labelling of the unintentional presence of allergens is less defined. Precautionary allergen labelling (PAL) was introduced by the food industry to help manage and communicate the risk of reaction from the unintended presence of allergens in foods. In its current form,...
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