Factors for Predicting the Therapeutic Efficacy of Laryngeal Contact Granuloma.

Factors for Predicting the Therapeutic Efficacy of Laryngeal Contact Granuloma.:

Factors for Predicting the Therapeutic Efficacy of Laryngeal Contact Granuloma.

J Voice. 2020 Sep 08;:

Authors: Nie Q, Li J, Zou S, Zhang R

Abstract

OBJECTIVE: To explore the factors affecting the therapeutic efficacy of laryngeal contact granuloma.

METHODS: The clinical data of 534 patients with laryngeal contact granuloma treated in our hospital from April 2014 to December 2019 were studied. The multivariable logistic regression was performed to find the risk factors influencing the treatment efficacy.

RESULTS: Multivariable logistic regression showed that factors related to therapeutic efficacy were granuloma size (P = 0.0006) and gender (P = 0.0299) in conservative treatment group; laryngopharyngeal reflux (P = 0.0115), cough (P = 0.0124), and previous surgical history (P < 0.001) in combined treatment group. The surgical treatment had the worst therapeutic efficacy compared with combined treatment and conservative treatment. In the larger granuloma size subgroup, combined treatment showed better results than conservative treatment.

CONCLUSION: Granuloma size and gender affect the therapeutic efficacy of conservative treatment. Previous surgical history, laryngopharyngeal reflux, and cough affect the therapeutic efficacy of combined treatment. Combined treatment is better than conservative treatment alone and surgical treatment shows the worst efficacy.



PMID: 32917458 [PubMed - as supplied by publisher]