Chinese Journal of Pathophysiology. Year 2019 Issue 06 is now available on CAOD.

In this issue: NO-sGC-cGMP signaling pathway regulates PAI-2 gene expression by cGK (NO-sGC-cGMP信号通路通过cGK调控PAI-2基因表达) HAN Jing-li, ,ZOU Li-hui, ,JIN Jun-hua, ,LI Wen-qing, ,LI Ying, ,XIAO Fei ...... page:961-967 CD137 signaling molecules promote proliferation of pulmonary artery en-dothelial cells by aerobic glycolysis (CD137信号通过有氧糖酵解途径促进小鼠肺动脉内皮细胞增殖) JIANG Mei-ping, ,CHEN Rui, ,LIU Pei-jing, ,YAN Jin-chuan ...... page:968-974 Mechanisms of histone acetylation modification in paternal alcohol con-sumption-induced heart development abnormalities of offspring (父代饮酒致子代小鼠心脏发育异常的组蛋白乙酰化修饰机制) LU Qian, ,ZHAO Wei-an, ,LIU Ling-juan, ,PAN Bo, ,TIAN Jie ...... page:975-980 Xinshuaikang inhibits myocardial autophagy and MAPK / ERK1 / 2 signa-ling pathway in rats with chronic heart failure (心衰康抑制慢性心衰大鼠心肌自噬及MAPK/ERK1/2信号通路) CHAI Song-bo, ,WANG Zhen-tao, ,ZHANG Shu-juan, ,LIU Shun-yu ...... page:981-987 Piperlongumine protects mice against diabetic cardiomyopathy by allevia-ting inflammation (荜茇酰胺通过抗炎作用缓解糖尿病心肌病小鼠的心肌病变) ZHUANG Fei, ,LIANG Guang, ,QIAN Jian-chang, ,ZHENG Chao ...... page:988-993 miR-34a induces senescence of bone marrow-derived mesenchymal stem cells under high glucose condition by SIRT1 (miR-34a通过SIRT1诱导高糖条件下骨髓间充质干细胞衰老) LIU Xiao-hong, ,ZHANG Feng-yun, ,WANG Kun, ,WANG Zhi-rong, ,ZHANG Zhuo-qi ...... page:994-1003 Role of lncRNA-MIAT in high glucose-induced viability enhancement in vascular smooth muscle cells (lncRNA-MIAT在高糖诱导血管平滑肌细胞活力增加中的作用) WANG Zheng, ,HU Fang, ,SUN Ying, ,CHEN Yang-li ...... page:1004-1009 Protective effect of Huangqi injection combined with puerarin injection on myocardium of type 2 diabetes mice (黄芪注射液联合葛根素注射液对2型糖尿病小鼠心肌的保护作用及其机制) WANG Qing-xia, ,CHEN Hui-gang, ,SUN Jing, ,SHI Yu-zhen, ,WANG Dian-wen ...... page:1010-1015 Low density lipoprotein from patients of diabetes mellitus induces apopto-sis of murine macrophages via activating caspase-12 pathway (糖尿病患者低密度脂蛋白通过激活caspase-12途径诱导小鼠巨噬细胞凋亡) WANG Zhi-chao, ,ZHANG Chi, ,ZHANG Yan, ,YUE Feng, ,TIAN Hua, ,JIAO Peng, ,QIN Shu-cun, ,XUE Ya-zhuo, ,YAO Shu-tong ...... page:1016-1022 Effects of autophagy inhibitor bafilomycin A1 on macrophages polarization (自噬抑制剂巴弗洛霉素A1对巨噬细胞极化的影响) WANG Fan, ,WANG Hao, ,SONG Xue-bin, ,SUN Hui-zhen, ,GUANG Jiao-na, ,NAN Wen-bin, ,ZHANG Qi-qing ...... page:1023-1028 Over-expression of PGC-1α inhibits apoptosis of mouse retinal photore-ceptor cells induced by high glucose (过表达PGC-1α 抑制高糖条件下小鼠视网膜感光细胞凋亡) LI Zhao-hui, ,ZHANG Rui, ,HE Jun-wen, ,LI Xiang-yun, ,WU Jian-hua ...... page:1029-1034 Let-7a-3p inhibits activity of cancer stem cells in human lung cancer A549 cells by targeting IGF1R (Let-7a-3p靶向IGF1R抑制人肺癌A549细胞中肿瘤干细胞的活性) WU Yuan-zhou, ,WANG Qiu-ping, ,XIAO Dan, ,ZHU Ya-ru, ,FANG Shun ...... page:1035-1041 Effect of 7-hydroxyisoflavone on HCT116 cells proliferation by Id1 (7-羟基异黄酮通过Id1影响结直肠癌细胞增殖) CHEN Hui-jing, ,LIAO Jin-rong, ,LI Jie-yu, ,YE Yun-bin ...... page:1042-1046 miR-125a-5p reverses cisplatin resistance of non-small-cell lung cancer A549 / DDP cells by targeting LIMK1 (miR-125a-5p靶向LIMK1逆转非小细胞肺癌A549/DDP细胞对顺铂的耐药性) LIU Yong-zhi, ,ZHANG Tong, ,SHEN Yi, ,DENG Shuang ...... page:1047-1054 MicroRNA-330 inhibits growth and migration of gastric cancer cells by directly targeting EGR-2 (MicroRNA-330靶向EGR-2基因抑制胃癌细胞生长和迁移) ZHAO Rong-rong, ,FU Zhao-yuan ...... page:1055-1062 IL-17 promotes viability and migration ability of endometrial carcinoma cells by inhibiting miR-195-5p expression (IL-17通过抑制miR-195-5p表达促进子宫内膜癌细胞生长和转移) XIAO Qing, ,LIU Li, ,HU Ya-jun, ,JIANG Liu, ,LI Jin-li, ,DENG Xiao-yan ...... page:1063-1068 Effect of lentinan on apoptosis and PI3K / AKT signaling pathway in leu-kemic HL-60 cells in vitro (香菇多糖在体外对白血病HL-60细胞凋亡及PI3K/AKT信号通路的影响) MA Li, ,RONG Fang, ,WANG Jian-bin, ,ZHANG Nian-ping, ,LIU Hong ...... page:1069-1074 Fucoidan sulfate promotes apoptosis of gastric cancer cells by regulating expression of HDAC1 (褐藻多糖硫酸酯通过调控HDAC1基因的表达促进胃癌细胞凋亡) YU Liang, ,JIANG Hui-li, ,LIU Hao-jie, ,HAN Wei ...... page:1075-1080 Over-expression of ACE2 gene alleviates Ang Ⅱ-induced oxidative stress in neural cells (ACE2基因过表达减轻血管紧张素Ⅱ诱导的神经细胞氧化应激) PENG Wen-wen, ,LIU Guo-ying, ,PAN Yan-xia, ,ZHAO Xiao-lin ...... page:1081-1088 Effects of Homer1a over-expression on apoptosis and AMPK protein ex-pression in mechanically injured neurons (过表达Homer1a对神经元机械性损伤模型的保护作用及可能机制) WANG Yuan, ,HE Zhu-qiang, ,LUO Ming, ,HUANG Cong-gang, ,SONG Ping, ,WANG Meng-yang, ,DUAN Fa-liang ...... page:1089-1094 Role of ghrelin in cell protection by up-regulating HSP70 through ERK1 / 2 signaling pathway in PC12 cells (Ghrelin通过ERK1/2磷酸化上调HSP70发挥细胞保护作用) SHI Ting, ,SONG Wei-fang, ,SUN Chang-wei, ,ZHU Shi-gong ...... page:1095-1100 Propofol inhibits LPS-induced inflammatory response in microglia via TRPV1 ion channels (异丙酚通过TRPV1离子通道抑制LPS诱导的小胶质细胞炎症反应) HUANG Bo-wan, ,HUANG Qiang, ,JIANG Yuan-xu ...... page:1101-1105 VEGF promotes biliary epithelial cell viability and cystic dilation in rats with polycystic kidney (血管内皮生长因子促多囊肾大鼠胆管上皮细胞活力及胆管囊性扩张的机制研究) LUAN Ming-yue, ,YAN Wen-di, ,LIU Te-si, ,Lü You, ,Yasunori SATO, ,PIAO Ying-shi, ,REN Xiang-shan ...... page:1106-1111 Lentiviral vector CV072-mediated Mfn2 over-expression inhibits hepatic stellate cell activation (慢病毒载体CV072介导的Mfn2过表达抑制肝星状细胞活化) ZHU Han-zhang, ,GE Ke, ,LIU Ling, ,SHEN Wei-min, ,JIA Chang-ku ...... page:1112-1117 Differentiation of rat bone marrow mesenchymal stem cells expressing hepatocyte growth factor into hepatocyte-like cells (表达肝细胞生长因子的大鼠骨髓间充质干细胞分化为肝样细胞) LI Shu-hua, ,GAO Li-lian, ,CHEN Xi-gu, ,FU Qiang, ,ZHANG Qi-hao ...... page:1118-1123 Effect of Jieyuwan on depression-like behaviors and expression of BDNF in hippocampus and prefrontal cortex of WKY rats (解郁丸对WKY大鼠的抑郁样行为及海马和前额叶皮层BDNF表达的影响) SONG Miao, ,LIU Hong-mei, ,LI Qi, ,ZHANG Yu, ,XU Yong ...... page:1124-1129 Anthocyanins attenuates hepatic fibrosis and inflammation in non-alcoho-lic fatty liver disease mice (白刺果提取物花色苷通过抑制肝脏纤维化及炎症减轻非酒精性脂肪性肝病) YANG Jiang-xia, ,BAI Jian-ying, ,LI Fu-ping, ,ZHANG Xiu-fen, ,XU Zhao-juan, ,ZHAO Dong ...... page:1130-1135 Effects of propofol on expression of CXCR4 / CXCR7 and migration abili-ty of human breast cancer MCF-7 cells in vitro (丙泊酚对乳腺癌MCF-7细胞CXCR4/CXCR7表达和体外迁移的影响) YANG Tao-bo, ,YI Han, ,SONG Juan, ,CHEN Fei, ,ZHU Ying, ,WANG Shou-yong ...... page:1136-1141 Effect of nicotine on systolic and diastolic function of rat aortic smooth muscle cells (尼古丁对大鼠主动脉平滑肌细胞舒缩功能的影响) LIU Ji-bin, ,QIN Xiao-jiang, ,YUE Han, ,YI Shu-xian, ,HOU Xiao-min ...... page:1142-1145,1152 Identification of tumor neoantigens based on multi-omics (基于多组学的肿瘤新抗原鉴定) JIA Zhong-juan, ,WANG Lin, ,TIAN Yi-ran, ,HAI Bo-ning, ,SHAO Ji-min ...... page:1146-1152