Chinese Pharmacological Bulletin. Year 2019 Issue 07 is now available on CAOD.

In this issue: Research and development of new drugs driven by novel generation AI technology (新一代人工智能技术驱动下的新药研发) WU Hao, ,LIN Ming, ,SUN Yi, ,ZHAO Xin, ,PU Xiao-ping ...... page:889-893 Research progress on epigenetic regulation-based mechanistic studies of Chinese herbal medicines in treatment of rheumatoid arthritis (基于表观遗传调控的中药防治类风湿关节炎作用机制研究进展) LIN Ye, ,LI Xin, ,YANG Zhen, ,TANG Lin, ,ZHANG Ting, ,YU Huang-he, ,DING Chang-song, ,LIAO Jing, ,CAI Xiong, ,LIU Liang ...... page:893-897 The pharmacokinetics, toxicology and pharmacology of oxymatrine (氧化苦参碱的药代动力学、毒理学及药理作用) GAO Pei-pei, ,WANG Zhen, ,LIU Jing, ,LONG Jian-gang ...... page:898-902 Progress in research of drugs for the treatment of pulmonary hypertension (抗肺动脉高压药物研究进展) LIANG Yu, ,DU Guan-hua ...... page:902-906 Advance of Reelin in Alzheimer's disease (Reelin蛋白在阿尔茨海默病中的研究进展) ZHOU Yu-jun, ,ZHANG Yong, ,HUANG Long-jian, ,LI Ping-ping, ,PENG Ying ...... page:907-910 Research progress in the roles and mechanisms of DLC2 in tumor (DLC2在肿瘤中作用及机制的研究进展) LI Xiao-man, ,WU Yuan-yuan, ,WANG Ai-yun, ,CHEN Wen-xing, ,LU Yin ...... page:911-914 Effect of PARP1 through regulating NFATs on cardiac hypertrophy (PARP1对NFATs的调控在病理性心肌肥大中的作用) GUO Kai-teng, ,LI Jing-yan, ,LU Jing, ,LIU Pei-qing ...... page:915-922 Inhibitory effect of resveratrol on MNNG-induced endometrial carcinogenesis based on estrogen metabolism regulation (基于雌激素代谢调控的白藜芦醇对MNNG诱导子宫内膜癌变的抑制作用) YIN Di, ,CHEN Chun-xia, ,MIN Meng-jun, ,ZHAO Feng, ,DU Lei, ,YIN Xiao-xing, ,ZHOU Xue-yan ...... page:922-928 Antagonistic effect of nimodipine on DBP-induced learning and memory impairment in KM mice (尼莫地平对邻苯二甲酸二丁酯所致小鼠学习记忆障碍的拮抗作用) WANG Long, ,GE Jian, ,CHEN Qian-xue, ,TIAN Dao-feng, ,LIU Bao-hui, ,YAN Biao ...... page:929-934 Effects of METH on mitochondrial membrane potrntial,ultrastaucture and expression of Mfn1 and Fis1 protein in SH-SY5Y cells cultured in vitro (甲基苯丙胺对体外培养SH-SY5Y细胞线粒体膜电位、超微结构及Mfn1、Fis1蛋白表达的影响) MOU Deng-feng, ,ZHENG Dan, ,WANG Qi, ,HUANG Shi-mei, ,GUAN Zhi-zhong, ,YU Yan-ni, ,LOU Di-dong ...... page:935-939 Expression of Krupple-like factor 6 and inducible nitric oxide synthase in apoptosis of RAW264. 7 infected by pseudomonas aeruginosa supernatant (Krupple样因子6及诱导型一氧化氮合酶在铜绿假单胞菌上清液感染RAW264.7凋亡过程中的表达) LIU Meng-ru, ,WANG Ya-qi, ,ZHANG Wei, ,YAO Fu-rong, ,CANG Lin, ,CHAI Wen-shu ...... page:940-944 Effect of RNA interfering Kv1. 3 channel expression on regulatory T lymphocytes in rats (靶向干扰Kv1.3通道基因表达对大鼠调节性T细胞的影响) LI Meng-jia, ,XU Qi, ,CHENG Lu-feng ...... page:945-949 Jar-TTA, a natural diterpenoid derivatives,induces apoptosis in human esophageal cancer cells through dual inhibition of glycolysis and oxidative phosphorylation (天然二萜衍生物Jar-TTA双重抑制糖酵解及氧化磷酸化诱导食管癌细胞凋亡) FAN Xia-xia, ,SU Nan, ,HUANG Xiao-jing, ,LI Ya-fei, ,JIA Ao, ,FAN Ji-pei, ,WANG Ai-feng, ,ZHAO Ning-min, ,MA Yong-cheng ...... page:950-958 The sequential switch from macroautophagy to chaperone-mediated autophagy in Raji cells induced by starvation (巨自噬与分子伴侣介导的自噬在饥饿诱导的Raji细胞中相继顺序被激活) LI Cai-li, ,XIN Ying, ,WEI Hu-lai, ,CHEN Jing, ,WANG Bei, ,LI Min ...... page:958-961 Effects of chemokine CCL2 on learning memory in rats and its mechanisms (趋化因子CCL2对大鼠学习记忆的影响及其机制) CHEN Jian-min, ,TAN Li-qiu, ,JIANG Jun-jun, ,LIANG Bing-yu, ,ZHOU Yan ...... page:962-967 Neuroprotective effects of salidroside on complement composition in cerebral ischemia / reperfusion injury rats (红景天苷抑制补体成分对脑缺血/再灌注大鼠的神经保护作用) HUANG Zuo, ,LIN Zuo, ,YANG Zelin, ,ZHANG Xiaoqin, ,XIE Xiuli, ,WANG Xuzuo, ,TANG Yuheng, ,LIU Junjie, ,LAI Wenfang, ,HONG Guizhu ...... page:967-972 Protective effects of urocortin on diabetic cardiomyopathy and relationship via Akt / GSK-3β signaling pathway (Urocortin对糖尿病心肌病的保护作用与Akt/GSK-3β信号通路的关系) LIU Xin-yu, ,LIU Chun-na, ,LI Si-xuan, ,ZHENG Chen, ,LIU Wan-zhu ...... page:973-977 Study of effect of rifampin and tanshinone ⅡA on pravastatin transport via BSEP in sandwich-cultured rat hepatocytes (在"三明治"培养大鼠原代肝细胞中研究利福平及联用丹参酮ⅡA对普伐他汀经BSEP转运的影响) LIU Lei, ,YANG Yu-jie, ,WANG Ling, ,JIANG Xue-hua ...... page:978-985 Identification and antibacterial activity of three mangrove-derived Streptomyces (三株红树林来源链霉菌的鉴定及抗菌活性研究) ZHENG Hong-yun, ,WU Yue, ,YE Jing-jing, ,CHEN Jian-hong, ,JIANG Lian-xiu, ,HE Yi, ,HUANG Da-lin ...... page:985-990 Protective effect of cardiomyopeptide on doxorubicin induced cell injury in H9c2 cardiomyocytes (心肌肽对阿霉素诱导心肌细胞H9c2损伤的影响) ZHANG Ting-ting, ,JIAO Jian, ,SHAO Chun-jun, ,LIU Jin-peng ...... page:991-994 Protective effect of resveratrol on oxidative stress injury of cardiomyocytes induced by high fat and its correlation with AMPK / mTORC1 / p70S6K signaling pathway (白藜芦醇对高脂所致心肌细胞氧化应激损伤的保护作用及其与AMPK/mTORC1/p70S6K信号通路的相关性) ZHANG Jing-yi, ,BAO Cui-yu, ,LI Jing ...... page:995-1000 The anti-colitic effect of specific Kv1. 3 blocker in its regulation of macrophage autophagy (特异性Kv1.3阻滞剂调节巨噬细胞自噬在抗结肠炎中的作用) MEI Yong-yu, ,FANG Chen, ,DING Shao-zhen, ,LIU Xiao-chang, ,XU Zhang-wei, ,HU Jing, ,XU Jian-ming, ,MEI Qiao ...... page:1001-1008 Acetylcholine protects high glucose-induced H9c2 cell injury by inhibiting autophagy (乙酰胆碱抑制自噬保护高糖诱导的H9c2细胞损伤) WANG Xun, ,KE Xuan, ,ZHANG Yuan-heng, ,ZHANG Chi, ,SUN Si-qin ...... page:1008-1013 Effect of Guiluerxianjiao on behaviors and HPA axis function in a rat model of post-traumatic stress disorder (龟鹿二仙胶对创伤后应激障碍大鼠行为学和HPA轴功能的影响) YE Wei-qiong, ,CHEN Jie, ,HUANG Yun-ling, ,NIU Jie, ,ZHU Peng-hui, ,WU Li-li, ,YAN Can ...... page:1014-1019 The improving effect of Zhimu-Huangbai herb pair on insulin resistance (药对知母-黄柏对胰岛素抵抗的改善作用) JIN Hui-jie, ,QIU Kun-cheng, ,LI Jia-hua, ,LIN Ai-hua, ,LIU Yi-ming ...... page:1020-1024 Construction of luciferase reporter gene cell model and its application in screening rhein derivatives targeting RAC1 (萤光素酶报告基因细胞模型在筛选靶向调控RAC1的大黄酸衍生物中的应用) LI Zhao-quan, ,SU Zheng-ying, ,LIANG Dan-dan, ,WANG Chun-miao, ,LAN Fu, ,LI Jun-ying, ,TIAN Wei, ,LI Dan-rong, ,HOU Hua-xin ...... page:1025-1030 A new perspective reexploration of neonatal mice glial culture in vitro and inflammatory model (新视角重探小鼠胶质细胞体外培养技术与炎症模型) WU Xiang-zhi, ,XU Ming-zhi, ,ZHANG Dong-wei, ,FU Jie, ,WANG Yi, ,SONG Hai-feng ...... page:1030-1036