Κυριακή 21 Ιουλίου 2019


IJMS, Vol. 20, Pages 3569: Identification of Jasmonic Acid Biosynthetic Genes in Sweet Cherry and Expression Analysis in Four Ancient Varieties from Tuscany
IJMS, Vol. 20, Pages 3569: Identification of Jasmonic Acid Biosynthetic Genes in Sweet Cherry and Expression Analysis in Four Ancient Varieties from Tuscany International Journal of Molecular Sciences doi: 10.3390/ijms20143569 Authors: Roberto Berni Giampiero Cai Xuan Xu Jean-Francois Hausman Gea Guerriero Sweet cherries are non-climacteric fruits whose early development is characterized by high levels of the phytohormone jasmonic acid (JA). Important parameters, such as...
International Journal of Molecular Sciences
03:00
IJMS, Vol. 20, Pages 3568: Cell Type-Specific TGF-β Mediated EMT in 3D and 2D Models and Its Reversal by TGF-β Receptor Kinase Inhibitor in Ovarian Cancer Cell Lines
IJMS, Vol. 20, Pages 3568: Cell Type-Specific TGF-β Mediated EMT in 3D and 2D Models and Its Reversal by TGF-β Receptor Kinase Inhibitor in Ovarian Cancer Cell Lines International Journal of Molecular Sciences doi: 10.3390/ijms20143568 Authors: Wafa Al Ameri Ikhlak Ahmed Fatima M. Al-Dasim Yasmin Ali Mohamoud Iman K. Al-Azwani Joel A. Malek Thasni Karedath Transcriptome profiling of 3D models compared to 2D models in various cancer cell lines shows differential expression...
International Journal of Molecular Sciences
03:00
Nutrients, Vol. 11, Pages 1677: Linseed Components Are More Effective Than Whole Linseed in Reversing Diet-Induced Metabolic Syndrome in Rats
Nutrients, Vol. 11, Pages 1677: Linseed Components Are More Effective Than Whole Linseed in Reversing Diet-Induced Metabolic Syndrome in Rats Nutrients doi: 10.3390/nu11071677 Authors: Siti Raihanah Shafie Stephen Wanyonyi Sunil K. Panchal Lindsay Brown Linseed is a dietary source of plant-based ω–3 fatty acids along with fiber as well as lignans including secoisolariciresinol diglucoside (SDG). We investigated the reversal of signs of metabolic syndrome...
Nutrients
03:00
JCM, Vol. 8, Pages 1072: Caregiver Burden and Sleep Quality in Dependent People’s Family Caregivers
JCM, Vol. 8, Pages 1072: Caregiver Burden and Sleep Quality in Dependent People’s Family Caregivers Journal of Clinical Medicine doi: 10.3390/jcm8071072 Authors: Miguel A. Simón Ana M. Bueno Patricia Otero Vanessa Blanco Fernando L. Vázquez This study examined the relationship between caregiver burden and sleep quality in dependent people’s family caregivers. A cross-sectional study was carried out with 201 dependent people’s family caregivers and 92 non-caregivers...
Journal of Clinical Medicine
03:00
Nanomaterials, Vol. 9, Pages 1044: Molecular Dynamics Simulation on Mechanical and Piezoelectric Properties of Boron Nitride Honeycomb Structures
Nanomaterials, Vol. 9, Pages 1044: Molecular Dynamics Simulation on Mechanical and Piezoelectric Properties of Boron Nitride Honeycomb Structures Nanomaterials doi: 10.3390/nano9071044 Authors: Lu Xie Tianhua Wang Chenwei He Zhihui Sun Qing Peng Boron nitride honeycomb structure is a new three-dimensional material similar to carbon honeycomb, which has attracted a great deal of attention due to its special structure and properties. In this paper, the tensile mechanical properties...
Nanomaterials
Sun Jul 21, 2019 03:00
MTI, Vol. 3, Pages 56: Promoting Sustainable Energy Consumption Behavior through Interactive Data Visualizations
MTI, Vol. 3, Pages 56: Promoting Sustainable Energy Consumption Behavior through Interactive Data Visualizations Multimodal Technologies and Interaction doi: 10.3390/mti3030056 Authors: Thomas Rist Masood Masoodian With an increasing worldwide need for energy and the ever-decreasing availability of energy resources, a wide range of interactive visualizations are being developed to allow people to use energy more efficiently by monitoring their consumption patterns and changing their...
Multimodal Technologies and Interaction
Sun Jul 21, 2019 03:00
IJERPH, Vol. 16, Pages 2599: Autonomy-Supportive Teaching and Basic Psychological Need Satisfaction among School Students: The Role of Mindfulness
IJERPH, Vol. 16, Pages 2599: Autonomy-Supportive Teaching and Basic Psychological Need Satisfaction among School Students: The Role of Mindfulness International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16142599 Authors: Chunxiao Li Ying Hwa Kee Leng Chee Kong Liye Zou Ka Lok Ng Hong Li Grounded in self-determination theory, the purpose of this study was to investigate the relationships between autonomy-supportive teaching, mindfulness, and...
International Journal of Environmental Research and Public Health
Sun Jul 21, 2019 03:00
Water, Vol. 11, Pages 1514: Raindrop Energy Impact on the Distribution Characteristics of Splash Aggregates of Cultivated Dark Loessial Cores
Water, Vol. 11, Pages 1514: Raindrop Energy Impact on the Distribution Characteristics of Splash Aggregates of Cultivated Dark Loessial Cores Water doi: 10.3390/w11071514 Authors: Yu Fu Guanglu Li Dong Wang Tenghui Zheng Mingxi Yang To determine the effect of different rainfall energy levels on the breakdown of soil aggregates, this study analyzed the soil splash erosion amounts and the distribution of particle sizes under six rainfall conditions (rainfall energy: 2.41 ×...
Water
Sun Jul 21, 2019 03:00
Water, Vol. 11, Pages 1515: Experimental Investigation of Local Scour Protection for Cylindrical Bridge Piers Using Anti-Scour Collars
Water, Vol. 11, Pages 1515: Experimental Investigation of Local Scour Protection for Cylindrical Bridge Piers Using Anti-Scour Collars Water doi: 10.3390/w11071515 Authors: Shunyi Wang Kai Wei Zhonghui Shen Qiqi Xiang Local scour of bridge piers is one of the main threats responsible for bridge damage. Adopting scour countermeasures to protect bridge foundations from scour has become an important issue for the design and maintenance of bridges located in erodible sediment beds....
Water
Sun Jul 21, 2019 03:00
Cosmetics, Vol. 6, Pages 44: Understanding the Global Sensory Landscape for Facial Cleansing/Makeup Remover Wipes
Cosmetics, Vol. 6, Pages 44: Understanding the Global Sensory Landscape for Facial Cleansing/Makeup Remover Wipes Cosmetics doi: 10.3390/cosmetics6030044 Authors: Huajing Xing Annlyse R. Krogmann Claudette Vaught Edgar Chambers Makeup chemistries have evolved over the recent years and have become more long-wearing, waterproof and difficult to remove. Thus, many changes have occurred among products designed to remove makeup. Specifically, the facial cleansing/makeup remover wipes...
Cosmetics
Sun Jul 21, 2019 03:00
Environments, Vol. 6, Pages 86: An Open Source GIS-Based Application for the Assessment of Groundwater Vulnerability to Pollution
Environments, Vol. 6, Pages 86: An Open Source GIS-Based Application for the Assessment of Groundwater Vulnerability to Pollution Environments doi: 10.3390/environments6070086 Authors: Lia Duarte Jorge Espinha Marques Ana Cláudia Teodoro Groundwater is a crucial natural resource for regular socio-economic function. Groundwater vulnerability to pollution can be assessed through Geographical Information System (GIS)-based qualitative methods. GIS-based tools, dedicated to the assessment...
Environments
Sun Jul 21, 2019 03:00
Molecules, Vol. 24, Pages 2646: Nutrition Quality Parameters of Almonds as Affected by Deficit Irrigation Strategies
Molecules, Vol. 24, Pages 2646: Nutrition Quality Parameters of Almonds as Affected by Deficit Irrigation Strategies Molecules doi: 10.3390/molecules24142646 Authors: Lipan Moriana Lluch Cano-Lamadrid Sendra Hernández Vázquez-Araújo Corell Carbonell-Barrachina The influence of full irrigation, double-regulated (RDI) and sustained deficit irrigation (SDI) treatments on almond quality was assessed by analyzing different parameters: sugars, organic acids,...
Molecules
Sun Jul 21, 2019 03:00
Bioengineering, Vol. 6, Pages 62: Forced Degradation Testing as Complementary Tool for Biosimilarity Assessment
Bioengineering, Vol. 6, Pages 62: Forced Degradation Testing as Complementary Tool for Biosimilarity Assessment Bioengineering doi: 10.3390/bioengineering6030062 Authors: Yan Felix Karl Dyck Daniel Rehm Jan Felix Joseph Karsten Winkler Volker Sandig Wolfgang Jabs Maria Kristina Parr Oxidation of monoclonal antibodies (mAbs) can impact their efficacy and may therefore represent critical quality attributes (CQA) that require evaluation. To complement classical CQA, bevacizumab...
Bioengineering
Sun Jul 21, 2019 03:00
Microorganisms, Vol. 7, Pages 208: Detoxification Strategies for Zearalenone Using Microorganisms: A Review
Microorganisms, Vol. 7, Pages 208: Detoxification Strategies for Zearalenone Using Microorganisms: A Review Microorganisms doi: 10.3390/microorganisms7070208 Authors: Nan Wang Weiwei Wu Jiawen Pan Miao Long Zearalenone (ZEA) is a mycotoxin produced by Fusarium fungi that is commonly found in cereal crops. ZEA has an estrogen-like effect which affects the reproductive function of animals. It also damages the liver and kidneys and reduces immune function which leads to cytotoxicity...
Microorganisms
Sun Jul 21, 2019 03:00
Microorganisms, Vol. 7, Pages 207: Upgrading Grape Pomace through Pleurotus spp. Cultivation for the Production of Enzymes and Fruiting Bodies
Microorganisms, Vol. 7, Pages 207: Upgrading Grape Pomace through Pleurotus spp. Cultivation for the Production of Enzymes and Fruiting Bodies Microorganisms doi: 10.3390/microorganisms7070207 Authors: Aikaterini Papadaki Vasiliki Kachrimanidou Seraphim Papanikolaou Antonios Philippoussis Panagiota Diamantopoulou Grape pomace, a by-product derived from winery industries, was used as fermentation media for the production of added-value products through the cultivation of two...
Microorganisms
Sun Jul 21, 2019 03:00
Cancers, Vol. 11, Pages 1027: Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells
Cancers, Vol. 11, Pages 1027: Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells Cancers doi: 10.3390/cancers11071027 Authors: Joaquín Marco-Brualla Sameer Al-Wasaby Ruth Soler Eduardo Romanos Blanca Conde Raquel Justo-Méndez José A. Enríquez Patricio Fernández-Silva Luis Martínez-Lostao Martín Villalba Raquel Moreno-Loshuertos Alberto Anel Multiprotein complexes...
Cancers
Sun Jul 21, 2019 03:00
Toxins, Vol. 11, Pages 428: Sclerostin as Regulatory Molecule in Vascular Media Calcification and the Bone–Vascular Axis
Toxins, Vol. 11, Pages 428: Sclerostin as Regulatory Molecule in Vascular Media Calcification and the Bone–Vascular Axis Toxins doi: 10.3390/toxins11070428 Authors: Annelies De Maré Stuart Maudsley Abdelkrim Azmi Jhana O. Hendrickx Britt Opdebeeck Ellen Neven Patrick C D’Haese Anja Verhulst Sclerostin is a well-known inhibitor of bone formation that acts on Wnt/β-catenin signaling. This manuscript considers the possible role of sclerostin in vascular calcification,...
Toxins
Sun Jul 21, 2019 03:00
Nanomaterials, Vol. 9, Pages 1042: Biosynthesis of Silver Nanoparticles Mediated by Extracellular Pigment from Talaromyces purpurogenus and Their Biomedical Applications
Nanomaterials, Vol. 9, Pages 1042: Biosynthesis of Silver Nanoparticles Mediated by Extracellular Pigment from Talaromyces purpurogenus and Their Biomedical Applications Nanomaterials doi: 10.3390/nano9071042 Authors: Sharad Bhatnagar Toshiro Kobori Deepak Ganesh Kazuyoshi Ogawa Hideki Aoyagi In recent years, green syntheses have been researched comprehensively to develop inexpensive and eco-friendly approaches for the generation of nanoparticles. In this context, plant and...
Nanomaterials
Sun Jul 21, 2019 03:00
Nanomaterials, Vol. 9, Pages 1043: Zinc Oxide Nanoparticles Induce Autophagy and Apoptosis via Oxidative Injury and Pro-Inflammatory Cytokines in Primary Astrocyte Cultures
Nanomaterials, Vol. 9, Pages 1043: Zinc Oxide Nanoparticles Induce Autophagy and Apoptosis via Oxidative Injury and Pro-Inflammatory Cytokines in Primary Astrocyte Cultures Nanomaterials doi: 10.3390/nano9071043 Authors: Woo-Ju Song Myung-Seon Jeong Dong-Min Choi Kil-Nam Kim Myung-Bok Wie The present study examined the potential toxic concentrations of zinc oxide nanoparticles (ZnO NPs) and associated autophagy and apoptosis-related injuries in primary neocortical astrocyte...
Nanomaterials
Sun Jul 21, 2019 03:00
Medicina, Vol. 55, Pages 394: The Influence of Bowel Preparation on ADC Measurements: Comparison between Conventional DWI and DWIBS Sequences
Medicina, Vol. 55, Pages 394: The Influence of Bowel Preparation on ADC Measurements: Comparison between Conventional DWI and DWIBS Sequences Medicina doi: 10.3390/medicina55070394 Authors: Ilze Apine Monta Baduna Reinis Pitura Juris Pokrotnieks Gaida Krumina Background and objectives: The aim of the study was to assess whether there were differences between apparent diffusion coefficient (ADC) values of diffusion-weighted imaging (DWI) and diffusion-weighted imaging with...
Medicina
Sun Jul 21, 2019 03:00
Medicina, Vol. 55, Pages 393: Intra-Nasally Administered Oligopeptide Lunasin Acts as a Possible Anti-Psychotic Agent in Mice Models
Medicina, Vol. 55, Pages 393: Intra-Nasally Administered Oligopeptide Lunasin Acts as a Possible Anti-Psychotic Agent in Mice Models Medicina doi: 10.3390/medicina55070393 Authors: Zane Dzirkale Ilva Nakurte Kaspars Jekabsons Ruta Muceniece Vija Klusa Background and Objectives: Previously we have shown that synthetic lunasin, a 43 amino acid residue-containing peptide, after its central (intracisternal) administration in mice demonstrated antagonism against dopaminergic drug...
Medicina
Sun Jul 21, 2019 03:00
Medicina, Vol. 55, Pages 392: Evaluation of Dyslipidaemia Using an Algorithm of Lipid Profile Measures among Newly Diagnosed Type II Diabetes Mellitus Patients: A Cross-Sectional Study at Dormaa Presbyterian Hospital, Ghana
Medicina, Vol. 55, Pages 392: Evaluation of Dyslipidaemia Using an Algorithm of Lipid Profile Measures among Newly Diagnosed Type II Diabetes Mellitus Patients: A Cross-Sectional Study at Dormaa Presbyterian Hospital, Ghana Medicina doi: 10.3390/medicina55070392 Authors: Enoch Odame Anto Christian Obirikorang Max Efui Annani-Akollor Eric Adua Sampson Donkor Emmanuel Acheampong Evans Adu Asamoah Background and Objectives: Dyslipidaemia and its associated complications...
Medicina
Sun Jul 21, 2019 03:00
Cells, Vol. 8, Pages 760: Neurological Enhancement Effects of Melatonin against Brain Injury-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration via AMPK/CREB Signaling
Cells, Vol. 8, Pages 760: Neurological Enhancement Effects of Melatonin against Brain Injury-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration via AMPK/CREB Signaling Cells doi: 10.3390/cells8070760 Authors: Shafiq Ur Rehman Muhammad Ikram Najeeb Ullah Sayed Ibrar Alam Hyun Young Park Haroon Badshah Kyonghwan Choe Myeong Ok Kim Oxidative stress and energy imbalance strongly correlate in neurodegenerative diseases. Repeated concussion is becoming...
Cells
Sun Jul 21, 2019 03:00
Cells, Vol. 8, Pages 759: The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System
Cells, Vol. 8, Pages 759: The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System Cells doi: 10.3390/cells8070759 Authors: Pontus Aspenström The Rho GTPases comprise a subfamily of the Ras superfamily of small GTPases. Their importance in regulation of cell morphology and cell migration is well characterized. According to the prevailing paradigm, Cdc42 regulates the formation of filopodia,...
Cells
Sun Jul 21, 2019 03:00
Cells, Vol. 8, Pages 758: Copine A Interacts with Actin Filaments and Plays a Role in Chemotaxis and Adhesion
Cells, Vol. 8, Pages 758: Copine A Interacts with Actin Filaments and Plays a Role in Chemotaxis and Adhesion Cells doi: 10.3390/cells8070758 Authors: Matthew J. Buccilli April N. Ilacqua Mingxi Han Andrew A. Banas Elise M. Wight Hanqian Mao Samantha P. Perry Tasha S. Salter David R. Loiselle Timothy A.J. Haystead Cynthia K. Damer Copines make up a family of calcium-dependent, phospholipid-binding proteins found in numerous eukaryotic organisms. Copine proteins...
Cells
Sun Jul 21, 2019 03:00
Molecules, Vol. 24, Pages 2645: Molecular Structure and Antioxidant Properties of Alkali Metal Salts of Rosmarinic Acid. Experimental and DFT Studies
Molecules, Vol. 24, Pages 2645: Molecular Structure and Antioxidant Properties of Alkali Metal Salts of Rosmarinic Acid. Experimental and DFT Studies Molecules doi: 10.3390/molecules24142645 Authors: Renata Świsłocka Ewa Regulska Joanna Karpińska Grzegorz Świderski Włodzimierz Lewandowski The molecular structure of alkali metal rosmarinates was studied in comparison to rosmarinic acid using FT-IR, FT-Raman, 1H and 13C NMR spectroscopy, as well as density functional theory...
Molecules
Sun Jul 21, 2019 03:00
Molecules, Vol. 24, Pages 2644: Novel Derivatives of Deoxycholic Acid Bearing Linear Aliphatic Diamine and Aminoalcohol Moieties and their Cyclic Analogs at the C3 Position: Synthesis and Evaluation of Their In Vitro Antitumor Potential
Molecules, Vol. 24, Pages 2644: Novel Derivatives of Deoxycholic Acid Bearing Linear Aliphatic Diamine and Aminoalcohol Moieties and their Cyclic Analogs at the C3 Position: Synthesis and Evaluation of Their In Vitro Antitumor Potential Molecules doi: 10.3390/molecules24142644 Authors: Andrey V. Markov Valeriya O. Babich Irina I. Popadyuk Oksana V. Salomatina Evgeniya B. Logashenko Nariman F. Salakhutdinov Marina A. Zenkova A series of novel deoxycholic acid (DCA) derivatives...
Molecules
Sun Jul 21, 2019 03:00
JoF, Vol. 5, Pages 68: The Burden of Serious Fungal Infections in Tajikistan
JoF, Vol. 5, Pages 68: The Burden of Serious Fungal Infections in Tajikistan Journal of Fungi doi: 10.3390/jof5030068 Authors: Oktam I. Bobokhojaev Ali Osmanov Samariddin P. Aliev Asliddin S. Radjabzoda Ziyovuddin T. Avgonov Safarbek T. Manonov David W. Denning Tajikistan is a low-income country in Middle Asia with a population of 8.9 million people. Five percent of the population lives on less than 1.9 USD a day and 54% live on less than 5.5 USD a day. We have estimated...
Journal of Fungi
Sun Jul 21, 2019 03:00
Water, Vol. 11, Pages 1510: Development of a Contaminant Distribution Model for Water Supply Systems
Water, Vol. 11, Pages 1510: Development of a Contaminant Distribution Model for Water Supply Systems Water doi: 10.3390/w11071510 Authors: Oluwaseye Samson Adedoja Yskandar Hamam Baset Khalaf Rotimi Sadiku Water contamination can result in serious health complications and gross socioeconomic implications. Therefore, identifying the source of contamination is of great concern to researchers and water operators, particularly, to avert the unfavorable consequences that can ensue...
Water
Sun Jul 21, 2019 03:00
Water, Vol. 11, Pages 1512: Effects of Artificial LED Light on the Growth of Three Submerged Macrophyte Species during the Low-Growth Winter Season: Implications for Macrophyte Restoration in Small Eutrophic Lakes
Water, Vol. 11, Pages 1512: Effects of Artificial LED Light on the Growth of Three Submerged Macrophyte Species during the Low-Growth Winter Season: Implications for Macrophyte Restoration in Small Eutrophic Lakes Water doi: 10.3390/w11071512 Authors: Chao Xu Hai-Jun Wang Qing Yu Hong-Zhu Wang Xiao-Min Liang Miao Liu Erik Jeppesen Eutrophication of lakes is becoming a global environmental problem, leading to, among other things, rapid reproduction of phytoplankton,...
Water
Sun Jul 21, 2019 03:00
Water, Vol. 11, Pages 1511: Assessing Reclaimed Urban Wastewater for Reuse in Agriculture: Technical and Economic Concerns for Mediterranean Regions
Water, Vol. 11, Pages 1511: Assessing Reclaimed Urban Wastewater for Reuse in Agriculture: Technical and Economic Concerns for Mediterranean Regions Water doi: 10.3390/w11071511 Authors: Giacomo Giannoccaro Stefania Arborea Bernardo C. de Gennaro Vito Iacobellis A. Ferruccio Piccinni Direct reuse of treated wastewater can offer a realistic supply alternative for irrigation in Mediterranean areas. In this study, we conducted a spatial cost-benefit analysis to quantify and...
Water
Sun Jul 21, 2019 03:00
Water, Vol. 11, Pages 1509: Net Fisheries’ Métiers in the Eastern Mediterranean: Insights for Small-Scale Fishery Management on Kalymnos Island
Water, Vol. 11, Pages 1509: Net Fisheries’ Métiers in the Eastern Mediterranean: Insights for Small-Scale Fishery Management on Kalymnos Island Water doi: 10.3390/w11071509 Authors: Kyriakoula Roditi Dimitris Vafidis Small-scale fisheries constitute an important component of coastal human societies. The present study describes the small-scale net fisheries on Kalymnos Island (south-east Aegean Sea) that harbors the largest small-scale fleet in the eastern Mediterranean Sea. In addition,...
Water
Sun Jul 21, 2019 03:00
Water, Vol. 11, Pages 1513: Cold Plasma Treatment for Efficient Control over Algal Bloom Products in Surface Water
Water, Vol. 11, Pages 1513: Cold Plasma Treatment for Efficient Control over Algal Bloom Products in Surface Water Water doi: 10.3390/w11071513 Authors: Hee-Jun Kim Gui-Sook Nam Jung-Seok Jang Chan-Hee Won Hyun-Woo Kim Algal bloom significantly alters the physicochemical properties of water due to drastic pH change, dissolved oxygen depletion/super-saturation, and toxicity, which lead to ecosystem destruction. To prevent this, this study evaluated the reduction performance...
Water
Sun Jul 21, 2019 03:00
Environments, Vol. 6, Pages 85: Assessment of Remote Sensing Data to Model PM10 Estimation in Cities with a Low Number of Air Quality Stations: A Case of Study in Quito, Ecuador
Environments, Vol. 6, Pages 85: Assessment of Remote Sensing Data to Model PM10 Estimation in Cities with a Low Number of Air Quality Stations: A Case of Study in Quito, Ecuador Environments doi: 10.3390/environments6070085 Authors: Cesar I. Alvarez-Mendoza Ana Claudia Teodoro Nelly Torres Valeria Vivanco The monitoring of air pollutant concentration within cities is crucial for environment management and public health policies in order to promote sustainable cities. In this...
Environments
Sun Jul 21, 2019 03:00

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