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Related ArticlesMedical Oncology Workload in Europe: One Continent, Several Worlds. Clin Oncol (R Coll Radiol). 2019 Jul 16;: Authors: Seruga B, Sullivan R, Fundytus A, Hopman WM, Ocana A, Joffe J, Bodoky G, Le Tourneau C, Vanderpuye V, Lopes G, Hammad N, Sengar M, Brundage MD, Booth CM Abstract AIMS: The workload pressure on medical oncologists will increase in the near future. There are no comprehensive data available about the current workload of...
Related ArticlesTumor-derived exosomes promote the in vitro osteotropism of melanoma cells by activating the SDF-1/CXCR4/CXCR7 axis. J Transl Med. 2019 Jul 19;17(1):230 Authors: Mannavola F, Tucci M, Felici C, Passarelli A, D'Oronzo S, Silvestris F Abstract BACKGROUND: Bone metastases occur rarely in patients suffering from malignant melanoma, although their onset severely worsens both prognosis and quality of life. Extracellular vesicles (EVs) including...
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Related ArticlesClinical Applications of Circulating Tumour DNA in Pancreatic Adenocarcinoma. J Pers Med. 2019 Jul 18;9(3): Authors: Loft M, Lee B, Tie J, Gibbs P Abstract Pancreatic adenocarcinoma remains one of the most aggressive cancers with an ongoing dismal survival rate despite some recent advances in treatment options. This is largely due to the typically late presentation and limited effective therapeutic options in advanced disease. There are...
Anticancer activity of emodin is associated with downregulation of CD155. Int Immunopharmacol. 2019 Jul 17;75:105763 Authors: Fang L, Zhao F, Iwanowycz S, Wang J, Yin S, Wang Y, Fan D Abstract Emodin is a Chinese herb-derived compound that exhibits a variety of pharmacological benefits. Although emodin has been shown to inhibit growth of cancer cells, its antineoplastic function is incompletely understood. CD155 is a member of poliovirus receptor-related...
Pro-differentiating and radiosensitizing effects of inhibiting HDACs by PXD-101 (Belinostat) in in vitro and in vivo models of human rhabdomyosarcoma cell lines. Cancer Lett. 2019 Jul 17;: Authors: Marampon F, Di Nisio V, Pietrantoni I, Petragnano F, Fasciani I, Scicchitano BM, Ciccarelli C, Gravina GL, Festuccia C, Del Fattore A, Tombolini M, De Felice F, Musio D, Cecconi S, Tini P, Maddalo M, Codenotti S, Fanzani A, Polimeni A, Maggio R, Tombolini V Abstract...
The mTOR Inhibitor Everolimus Overcomes CXCR4-Mediated Resistance to Histone Deacetylase Inhibitor Panobinostat through Inhibition of p21 and Mitotic Regulators. Biochem Pharmacol. 2019 Jul 17;: Authors: Beider K, Bitner H, Voevoda-Dimenshtein V, Rosenberg E, Sirovsky Y, Magen H, Canaani J, Ostrovsky O, Shilo N, Shimoni A, Abraham M, Weiss L, Milyavsky M, Peled A, Nagler A Abstract Although having promising anti-myeloma properties, the pan-histone deacetylase...
Related ArticlesSystematic cancer-testis gene expression analysis identified CDCA5 as a potential therapeutic target in esophageal squamous cell carcinoma. EBioMedicine. 2019 Jul 16;: Authors: Xu J, Zhu C, Yu Y, Wu W, Cao J, Li Z, Dai J, Wang C, Tang Y, Zhu Q, Wang J, Wen W, Xue L, Zhen F, Liu J, Huang C, Zhao F, Zhou Y, He Z, Pan X, Wei H, Zhu Y, He Y, Que J, Luo J, Chen L, Wang W Abstract BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one...
Related ArticlesMethylation Dynamics of RASSF1A and Its Impact on Cancer. Cancers (Basel). 2019 Jul 09;11(7): Authors: Malpeli G, Innamorati G, Decimo I, Bencivenga M, Nwabo Kamdje AH, Perris R, Bassi C Abstract 5-methyl cytosine (5mC) is a key epigenetic mark entwined with gene expression and the specification of cellular phenotypes. Its distribution around gene promoters sets a barrier for transcriptional enhancers or inhibitor proteins binding to...
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Related ArticlesTotal rhinectomy for nasal carcinomas. Braz J Otorhinolaryngol. 2019 Jul 02;: Authors: Girardi FM, Hauth LA, Abentroth AL Abstract INTRODUCTION: Total rhinectomy is an uncommon procedure for the treatment of nasal malignancies, usually reserved for locally advanced tumors. There are few case series studying total rhinectomy in the literature, reporting conflicting results about recurrence and metastasis. OBJECTIVE: Evaluate prognosis...
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Related ArticlesSensorineural hearing loss in the acute phase of a single episode of acute otitis media. Braz J Otorhinolaryngol. 2019 Jul 02;: Authors: Kasemodel ALP, Costa LEM, Monsanto RDC, Tomaz A, Penido NO Abstract INTRODUCTION: Acute otitis media is a disease with high global prevalence, that can lead to several acute complications and auditory sequelae. Data regarding the auditory evaluation in the acute phase of acute otitis media are scarce....
Iodine immobilization by silver-impregnated granular activated carbon in cementitious systems. J Environ Radioact. 2019 Jul 17;208-209:106017 Authors: Li D, Kaplan DI, Price KA, Seaman JC, Roberts K, Xu C, Lin P, Xing W, Schwehr K, Santschi PH Abstract Silver (Ag)-based technologies are amongst the most common approaches to removing radioiodine from aqueous waste streams. As a result, a large worldwide inventory of radioactive AgI waste presently exits,...
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Related ArticlesTrends in the initial management of vestibular schwannoma in the United States. J Clin Neurosci. 2019 Jul 16;: Authors: Leon J, Trifiletti DM, Waddle MR, Vallow L, Ko S, May B, Tzou K, Ruiz-Garcia H, Lundy L, Chaichana K, Vibhute P, Peterson JL Abstract INTRODUCTION: Vestibular schwannomas are benign tumors of the 8th cranial nerve. Initial treatment options include active surveillance, surgery, and/or radiation therapy. We analyzed the...
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