Let me share two CXR of a Patient with COVID19, note the peripheral consolidation in the initial CXR and see the CXR done 8-10 days later with extensive bilateral peripheral consolidation. For the medical students and residents following this page please note The most frequent CXR findings are airspace opacities, consolidation or ground glass opacities. The distribution is most often bilateral, peripheral, and lower zone predominant. Pleural effusion is rare.Famous Radiology Blog http://www.sumerdoc.blogspot.com...
09:15
Related Articles Efficacy of telemonitoring system in continuous positive airway pressure therapy in Asian obstructive sleep apnea. J Clin Sleep Med. 2020 Sep 08;: Authors: Chumpangern W, Muntham D, Chirakalwasan N Abstract STUDY OBJECTIVES: Telemonitoring system is a promising wireless technology which possibly enhances the adherence to CPAP therapy. The study aimed to determine the effect of telemonitoring system on CPAP therapy adherence...
Wed Sep 09, 2020 14:16
Related Articles Relationship between sleep-disordered breathing and central systolic blood pressure in a community-based population: the Toon Health Study. Hypertens Res. 2019 07;42(7):1074-1082 Authors: Igami K, Maruyama K, Tomooka K, Ikeda A, Tabara Y, Kohara K, Saito I, Tanigawa T Abstract Sleep-disordered breathing (SDB) is linked with brachial blood pressure. Although central systolic blood pressure (cSBP) is a better predictor of cardiovascular...
Wed Sep 09, 2020 14:16
Related Articles Bilateral endophthalmitis as the initial presentation of pneumococcal endocarditis. Enferm Infecc Microbiol Clin. 2019 Aug - Sep;37(7):488-490 Authors: Fernández-Ruiz M, Vargas JC, Ruiz-Ruigómez M PMID: 30553620 [PubMed - indexed for MEDLINE]
Wed Sep 09, 2020 14:16
Related Articles Standardizing Postoperative Rehabilitation Protocols for the Tri-Service: A Consensus Meeting Hosted by the Musculoskeletal Injury Rehabilitation Research for Operational Readiness Organization. Mil Med. 2020 Sep 08;: Authors: Isaacson B, Miranda M, Hager N, Wagner L, West S, Lucio W, Heller J, Dalgarno R, Dickens JF, Schoomaker E, Pasquina P PMID: 32897320 [PubMed - as supplied by publisher]
Wed Sep 09, 2020 14:09
237 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/09/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Sep 09, 2020 14:07
Related Articles Virtual Reality Surgical Rehearsal and 2-Dimensional Operative Video of a Paramedian Supracerebellar Infratentorial Approach Endoscopic Resection of Pineocytoma: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2020 Sep 07;: Authors: Jean WC Abstract An endoscopic "keyhole" approach to a deep-lying skull base lesion can be a daunting challenge. For the pineal region, the techniques for endoscopic resection of solid...
Wed Sep 09, 2020 14:06
113 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/09/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Sep 09, 2020 14:04
BACKGROUND AND PURPOSE: Parathyroid gland weight is a clinically relevant parameter used to diagnose parathyroid adenomas intraoperatively. We evaluated the accuracy of a formula to estimate parathyroid weight on preoperative 4D-CT. MATERIALS AND METHODS: A single-institution retrospective study was performed in patients with primary hyperparathyroidism who underwent 4D-CT between January 2013 and December 2014 with subsequent parathyroidectomy and surgical cure. All patients had correct...
Wed Sep 09, 2020 13:21
SUMMARY: Malignant epithelioid glioneuronal tumor is a rare high-grade, aggressive brain tumor that shows both glial and neuronal differentiation on histopathology but is not included in the current World Health Organization classification. The neuroimaging appearance is variable but may be secondary to the size of the mass and/or location of the tumor. In our series, all epithelioid glioneuronal tumors were encountered in the supratentorial space and included pineal, temporal, and extratemporal...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Endovascular navigation through tortuous vessels can be complex. Tools that can optimise this access phase need to be developed. Our aim was to evaluate the feasibility of supra-aortic vessel catheterization guidance by means of live fluoroscopy fusion with MR angiography or CT angiography. MATERIALS AND METHODS: Twenty-five patients underwent preinterventional diagnostic MRA, and 8 patients underwent CTA. Fusion guidance was evaluated in 35 sessions of catheterization,...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Internal auditory canal diverticula are focal lucencies along the anterior-inferior aspect of the internal auditory canal fundus. Studies in adults report conflicting data on the etiology and clinical relevance of this finding. We would expect a pediatric study to help elucidate the significance of internal auditory canal diverticula. The primary goals of this study were to determine the temporal bone CT prevalence of diverticula among pediatric patients and to assess possible...
Wed Sep 09, 2020 13:21
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: After endovascular treatment of intracranial aneurysms with the Woven EndoBridge (WEB) device, worsening of aneurysm occlusion or re-opening was reported to be possibly associated with WEB shape modification. This study analyzed quantitatively the WEB shape modification with time in association with anatomic results. MATERIALS AND METHODS: Thirty patients with 32 WEB-treated intracranial aneurysms fulfilled the inclusion criteria of cranial CT at baseline (day of...
Wed Sep 09, 2020 13:21
SUMMARY: Coronavirus disease 2019 (COVID-19) is associated with a severe inflammatory response. Inflammation affects atherosclerotic plaque vulnerability and promotes a thrombogenic environment. We report a series of 6 patients with COVID-19 with acute ischemic stroke due to intraluminal carotid artery thrombus presenting during an 8-day period. Six patients were included (5 men) with a mean age of 65.8 years (range, 55–78 years). COVID-19 was diagnosed by detection of Severe Acute Respiratory...
Wed Sep 09, 2020 13:21
SUMMARY: Radiologically isolated syndrome refers to an entity in which white matter lesions fulfilling the criteria for multiple sclerosis occur in individuals without a history of a clinical demyelinating attack or alternative etiology. Since its introduction in 2009, the diagnostic criteria of radiologically isolated syndrome and its clinical relevance have been widely debated by neurologists and radiologists. The aim of the present study was to review the following: 1) historical evolution of...
Wed Sep 09, 2020 13:21
SUMMARY: Patients with coronavirus disease 2019 (COVID-19) may have symptoms of anosmia or partial loss of the sense of smell, often accompanied by changes in taste. We report 5 cases (3 with anosmia) of adult patients with COVID-19 in whom injury to the olfactory bulbs was interpreted as microbleeding or abnormal enhancement on MR imaging. The patients had persistent headache (n = 4) or motor deficits (n = 1). This olfactory bulb injury may be the mechanism by which the Severe Acute Respiratory...
Wed Sep 09, 2020 13:21
SUMMARY: Tumor resection followed by chemoradiation remains the current criterion standard treatment for high-grade gliomas. Regardless of aggressive treatment, tumor recurrence and radiation necrosis are 2 different outcomes. Differentiation of tumor recurrence from radiation necrosis remains a critical problem in these patients because of considerable overlap in clinical and imaging presentations. Contrast-enhanced MR imaging is the universal imaging technique for diagnosis, treatment evaluation,...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Anisotropy is a good indicator of white matter fascicle macrostructure and organization but the interpretation of its changes with age remains difficult. The increase of WM fascicle fractional anisotropy with time and its relationship with WM fascicle volume have never been examined during childhood. We studied the maturation of associative WM fascicles during childhood using MR imaging–based DTI. We explored whether the fractional anisotropy increase of the main WM fascicles...
Wed Sep 09, 2020 13:21
SUMMARY: Deep brain stimulation is an established therapy for multiple brain disorders, with rapidly expanding potential indications. Neuroimaging has advanced the field of deep brain stimulation through improvements in delineation of anatomy, and, more recently, application of brain connectomics. Older lesion-derived, localizationist theories of these conditions have evolved to newer, network-based "circuitopathies," aided by the ability to directly assess these brain circuits in vivo through...
Wed Sep 09, 2020 13:21
SUMMARY: Spinal CSF–venous fistulas are a cause of spontaneous intracranial hypotension that can be difficult to detect on imaging. We describe how the respiratory phase affects the visibility of CSF–venous fistulas during myelography.
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Cellular uptake of the manganese ion, when administered as a contrast agent for MR imaging, can noninvasively highlight cellular activity and disease processes in both animals and humans. The purpose of this study was to explore the enhancement profile of manganese in patients with multiple sclerosis. MATERIALS AND METHODS: Mangafodipir is a manganese chelate that was clinically approved for MR imaging of liver lesions. We present a case series of 6 adults with multiple...
Wed Sep 09, 2020 13:21
SUMMARY: There is increasing evidence to suggest that complications of coronavirus disease 2019 (COVID-19) infection are not only limited to the pulmonary system but can also involve the central nervous system. Here, we report 6 critically ill patients with COVID-19 infection and neuroimaging findings of leukoencephalopathy. While these findings are nonspecific, we postulate that they may be a delayed response to the profound hypoxemia the patients experienced due to the infection. No abnormal...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: It is unknown whether deceleration of brain atrophy is associated with disability improvement in patients with MS. Our aim was to investigate whether patients with MS with disability improvement develop less brain atrophy compared with those who progress in disability or remain stable. MATERIALS AND METHODS: We followed 980 patients with MS for a mean of 4.8 ± 2.4 years. Subjects were divided into 3 groups: progress in disability (n = 241, 24.6%), disability improvement...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Management of contrast media allergies may lead to treatment delays in patients with acute ischemic stroke undergoing endovascular therapy. The optimal premedication strategy remains unclear. The aim of this report was to analyze our experience with emergent administration of premedication regimens before endovascular therapy. MATERIALS AND METHODS: We retrospectively reviewed prospective data for all patients undergoing endovascular therapy from 2012 to 2019 at an...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Slowly expanding/evolving lesions measured by conventional T1-weighted/T2-weighted brain MR imaging may contribute to progressive disability accumulation in MS. We evaluated the longitudinal change in myelin and axonal tissue integrity in white matter slowly expanding/evolving lesions by means of the magnetization transfer ratio and DTI radial diffusivity. MATERIALS AND METHODS: Slowly expanding/evolving lesions were detected within the Study to Assess the Efficacy,...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Impairment of macrophage polarization from a proinflammatory macrophage type 1 (M1) population to an anti-inflammatory macrophage type 2 (M2) population is a hallmark of poor wound healing. In this study, we aimed to evaluate the distribution of M1 and M2 macrophages and to analyze their association with healing in aneurysms embolized by endovascular coiling. MATERIALS AND METHODS: Elastase-induced aneurysms were created in female rabbits and subsequently embolized...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Increased contrast enhancement has been used as a marker of malignant transformation in low-grade gliomas. This marker has been found to have limited accuracy because many low-grade gliomas with increased contrast enhancement remain grade II. We aimed to investigate whether MR spectroscopy can contribute to the diagnosis of malignant transformation in low-grade gliomas with increased contrast enhancement. MATERIALS AND METHODS: Patients with low-grade gliomas who...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Clinical outcomes after endovascular treatment for acute basilar artery occlusions need further investigation. Our aim was to analyze predictors of a 90-day good functional outcome defined as mRS 0–2 after endovascular treatment in MR imaging–selected patients with acute basilar artery occlusions. MATERIALS AND METHODS: We analyzed consecutive MR imaging–selected patients with acute basilar artery occlusions endovascularly treated within the first 24 hours after symptom...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Carotid-cavernous fistulas are abnormal vascular shunts that can cause various neurologic or orbital symptoms. The purpose of this retrospective study was to evaluate the diagnostic performance of thin-section MR imaging for carotid cavernous fistula in patients with clinically suspected carotid cavernous fistula, and to identify possible imaging predictors of carotid cavernous fistula. MATERIALS AND METHODS: A total of 98 patients who were clinically suspected of...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Hypophysitis is one of the well-known adverse effects of immune checkpoint inhibitors. Immune checkpoint inhibitor–induced hypophysitis frequently causes irreversible hypopituitarism, which requires long-term hormone replacement. Despite the high frequency and clinical significance, characteristic MR imaging findings of immune checkpoint inhibitor–induced hypophysitis have not been established. In the present study, we aimed to review and extract the MR imaging features...
Wed Sep 09, 2020 13:21
BACKGROUND: The utility of vessel wall MR imaging in identifying unstable intracranial aneurysms has been suggested but remains controversial. PURPOSE: Our aim was to provide further insight into the potential relationship between aneurysm wall enhancement on initial vessel wall imaging and aneurysm instability at follow-up. DATA SOURCES: Our sources were PubMed, Scopus, the Web of Science, and the Cochrane Central Register of Controlled Trials. STUDY SELECTION: We searched...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Although olfactory dysfunction is a common cranial nerve disorder, there are no simple objective morphometric criteria to assess olfactory dysfunction. The aim of this study was to evaluate the diagnostic performance of MR imaging morphometric parameters for detecting olfactory dysfunction. MATERIALS AND METHODS: This prospective study enrolled patients from those presenting with olfactory symptoms who underwent both an olfactory function test and MR imaging. Controls...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Thrombectomy up to 24 hours after stroke onset in patients with specific ischemic brain volumes remains a challenge, because many stroke centers do not apply specialized software to calculate ischemic volumes at advanced imaging. We aimed to establish the association between relative filling time delay on CTP source imaging and ischemic volume parameters and the infarct penumbra to core volume mismatch in patients with acute ischemic stroke. MATERIALS AND METHODS: ...
Wed Sep 09, 2020 13:21
SUMMARY: We report a case of bifacial weakness with paresthesia, a recognized Guillain-Barré syndrome subtype characterized by rapidly progressive facial weakness and paresthesia without ataxia or other cranial neuropathies, which was temporally associated with antecedent coronavirus 2019 (COVID-19). This case highlights a potentially novel but critically important neurologic association of the COVID-19 disease process. Herein, we detail the clinicoradiologic work-up and diagnosis, clinical course,...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Although chronic ischemia is known to induce myelin and axonal damage in animal models, knowledge regarding patients with Moyamoya disease is limited. We aimed to investigate the presence of myelin and axonal damage in Moyamoya disease and their relationship with cognitive performance. MATERIALS AND METHODS: Eighteen patients with Moyamoya disease (16–55 years of age) and 18 age- and sex-matched healthy controls were evaluated with myelin-sensitive MR imaging based...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Posterior fossa tumors are the most common pediatric brain tumors. MR imaging is key to tumor detection, diagnosis, and therapy guidance. We sought to develop an MR imaging–based deep learning model for posterior fossa tumor detection and tumor pathology classification. MATERIALS AND METHODS: The study cohort comprised 617 children (median age, 92 months; 56% males) from 5 pediatric institutions with posterior fossa tumors: diffuse midline glioma of the pons (n =...
Wed Sep 09, 2020 13:21
SUMMARY: Neurologic findings are being increasingly recognized in coronavirus disease 2019. We present a patient with a unique involvement of the corpus callosum that we relate to the cytokine storm seen in patients with Severe Acute Respiratory Syndrome coronavirus 2 infection. As the infection is increasingly seen around the world, recognition of these unique patterns may facilitate early identification of the progression of this disease and potentially facilitate appropriate management.
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: Focal areas of high signal intensity are T2WI/T2-FLAIR hyperintensities frequently found on MR imaging of children diagnosed with neurofibromatosis type 1, often thought to regress spontaneously during adolescence or puberty. Due to the risk of tumor in this population, some focal areas of high signal intensity may pose diagnostic problems. The objective of this study was to assess the characteristics and temporal evolution of focal areas of high signal intensity in children...
Wed Sep 09, 2020 13:21
SUMMARY: The thalamus consists of several functionally distinct nuclei, some of which serve as targets for functional neurosurgery. Visualization of such nuclei is a major challenge due to their low signal contrast on conventional imaging. We introduce MR susceptibility imaging with a short TE, leveraging susceptibility differences among thalamic nuclei, to automatically delineate 15 thalamic subregions. The technique has the potential to enable direct targeting of thalamic nuclei for functional...
Wed Sep 09, 2020 13:21
BACKGROUND AND PURPOSE: DTI has been proved valuable for the diagnosis of degenerative cervical myelopathy, whereas its capacity for predicting the outcome of surgery is still under debate. Here we conduct a prospective cohort study to analyze the capacity of DTI for evaluating and predicting laminoplasty surgery outcome for degenerative cervical myelopathy. MATERIALS AND METHODS: We recruited 55 patients with degenerative cervical myelopathy who underwent DTI before surgery and at 3- and...
Wed Sep 09, 2020 13:21
SUMMARY: We present a series of 10 hospitalized patients with confirmed coronavirus 2019 infections who developed severe neurovascular complications and discuss the possible reasons for these findings and their relationship to the novel Severe Acute Respiratory Syndrome coronavirus 2 infection.
Wed Sep 09, 2020 13:21
Wed Sep 09, 2020 13:21
Related Articles Transcervical (SP) and Transhiatal DaVinci Robotic Esophagectomy: A Cadaveric Study. Thorac Cardiovasc Surg. 2020 Sep 08;: Authors: van der Sluis P, Egberts JH, Stein H, Sallum R, van Hillegersberg R, Grimminger PP Abstract BACKGROUND: This is a preclinical cadaveric study to investigate the feasibility of a fully robotic McKeown esophagectomy in simultaneous rendezvous technique using the DaVinci X for transhiatal dissection...
Wed Sep 09, 2020 13:57
Related Articles Parent-Child Communication and Reproductive Considerations in Families with Genetic Cancer Predisposition Syndromes: A Systematic Review. J Adolesc Young Adult Oncol. 2020 Sep 08;: Authors: Dattilo TM, Lipak KG, Clark OE, Gehred A, Sampson A, Quinn G, Zajo K, Sutter ME, Bowman-Curci M, Gardner M, Gerhardt CA, Nahata L Abstract Background: Uptake of genetic testing for heritable conditions is increasingly common. In families...
Wed Sep 09, 2020 13:57
Related Articles Future challenges and chances in the diagnosis and management of invasive mould infections in cancer patients. Med Mycol. 2020 Sep 08;: Authors: Vehreschild JJ, Koehler P, Lamoth F, Prattes J, Rieger C, Rijnders BJA, Teschner D Abstract Diagnosis, treatment, and management of invasive mould infections (IMI) are challenged by several risk factors, including local epidemiological characteristics, the emergence of fungal resistance...
Wed Sep 09, 2020 13:57
Related Articles The Use of Activity Trackers in Interventions for Childhood Cancer Patients and Survivors: A Systematic Review. J Adolesc Young Adult Oncol. 2020 Sep 04;: Authors: Ha L, Mizrahi D, Wakefield CE, Cohn RJ, Simar D, Signorelli C Abstract Activity trackers have emerged as promising devices used to motivate and/or objectively monitor physical activity (PA) levels. It is unknown how activity trackers have been used in interventions...
Wed Sep 09, 2020 13:57
Related Articles Beyond lipid-lowering: role of statins in endometrial cancer. Mol Biol Rep. 2020 Sep 08;: Authors: Hafizz AMHA, Zin RRM, Aziz NHA, Kampan NC, Shafiee MN Abstract As the obesity rates dramatically increased across the globe, the risk of endometrial cancer (EC) has substantially increased. Measures to improve the EC outcome is utmost important, especially data have shown that women at their reproductive age are commonly affected....
Wed Sep 09, 2020 13:57
Related Articles Correction to: Genetic susceptibility to neuroblastoma: current knowledge and future directions. Cell Tissue Res. 2020 Sep 08;: Authors: Ritenour LE, Randall MP, Bosse KR, Diskin SJ Abstract The online HTML version of the article contains an error in Table 2. PMID: 32897422 [PubMed - as supplied by publisher]
Wed Sep 09, 2020 13:57
Prognostic significance for colorectal carcinoid tumors based on the 8th edition TNM staging system.
Related Articles Prognostic significance for colorectal carcinoid tumors based on the 8th edition TNM staging system. Cancer Med. 2020 Sep 08;: Authors: Gong P, Chen C, Wang Z, Zhang X, Hu W, Hu Z, Li X Abstract The aim of our study was to explore the value of the 8th edition TNM staging system on evaluating the prognosis of colorectal carcinoid. Colorectal carcinoid patients between 1988 and 2015 were selected in the Surveillance, Epidemiology,...
Wed Sep 09, 2020 13:57
Related Articles 10-day decitabine with venetoclax for newly diagnosed intensive chemotherapy ineligible, and relapsed or refractory acute myeloid leukaemia: a single-centre, phase 2 trial. Lancet Haematol. 2020 Sep 04;: Authors: DiNardo CD, Maiti A, Rausch CR, Pemmaraju N, Naqvi K, Daver NG, Kadia TM, Borthakur G, Ohanian M, Alvarado Y, Issa GC, Montalban-Bravo G, Short NJ, Yilmaz M, Bose P, Jabbour EJ, Takahashi K, Burger JA, Garcia-Manero G, Jain N, Kornblau...
Wed Sep 09, 2020 13:57
Related Articles Feasibility of Delivering an Avatar-Facilitated Life Review Intervention for Patients with Cancer. J Palliat Med. 2020 Sep 03;: Authors: Dang M, Noreika D, Ryu S, Sima A, Ashton H, Ondris B, Coley F, Nestler J, Fabbro ED Abstract Background: Life review, a narrative-based intervention, helps individuals organize memories into a meaningful whole, providing a balanced view of the past, present, and future. Examining how the...
Wed Sep 09, 2020 13:57
Related Articles The influence of perceived racial bias and health-related stigma on quality of life among children with sickle cell disease. Ethn Health. 2020 Sep 08;:1-14 Authors: Hood AM, Crosby LE, Hanson E, Shook LM, Lebensburger JD, Madan-Swain A, Miller MM, Trost Z Abstract Objectives: Individuals with sickle cell disease (SCD) experience significant health problems that may result in unpredictable pain episodes and frequent healthcare...
Wed Sep 09, 2020 13:57
Related Articles Bladder preservation therapy for muscle invasive bladder cancer: the past, present and future. Jpn J Clin Oncol. 2020 Sep 07;: Authors: Kimura T, Ishikawa H, Kojima T, Kandori S, Kawahara T, Sekino Y, Sakurai H, Nishiyama H Abstract Radical cystectomy is the gold standard treatment for muscle invasive bladder cancer, but some patients have medically inoperable disease or refuse cystectomy to preserve their bladder function....
Wed Sep 09, 2020 13:57
Related Articles Prospective validation of classification of intraoperative adverse events (ClassIntra): international, multicentre cohort study. BMJ. 2020 08 25;370:m2917 Authors: Dell-Kuster S, Gomes NV, Gawria L, Aghlmandi S, Aduse-Poku M, Bissett I, Blanc C, Brandt C, Ten Broek RB, Bruppacher HR, Clancy C, Delrio P, Espin E, Galanos-Demiris K, Gecim IE, Ghaffari S, Gié O, Goebel B, Hahnloser D, Herbst F, Orestis I, Joller S, Kang S, Martín R, Mayr J, Meier...
Wed Sep 09, 2020 13:57
Related Articles Results of CoALL 07-03 study childhood ALL based on combined risk assessment by in vivo and in vitro pharmacosensitivity. Blood Adv. 2019 11 26;3(22):3688-3699 Authors: Schramm F, Zur Stadt U, Zimmermann M, Jorch N, Pekrun A, Borkhardt A, Imschweiler T, Christiansen H, Faber J, Schmid I, Feuchtinger T, Beron G, den Boer ML, Pieters R, Horstmann MA, Janka-Schaub GE, Escherich G Abstract We conducted a clinical trial and report...
Wed Sep 09, 2020 13:57
Related Articles Myeloablative Unrelated Cord Blood Transplantation in Adolescents and Young Adults with Acute Leukemia. Biol Blood Marrow Transplant. 2019 12;25(12):2438-2446 Authors: Hayashi H, Volt F, Sanz J, Petersen E, Dhedin N, Hough R, Milpied N, Angelucci E, Yakoub-Agha I, Michallet M, Michel G, Aljurf M, Kenzey C, Rocha V, Dalle JH, Bader P, Ruggeri A, Gluckman E, Eurocord, Cellular Therapy & Immunobiology Working Party, and Paediatric Diseases...
Wed Sep 09, 2020 13:57
Related Articles Human papilloma virus induced oropharyngeal inverted papilloma as a precursor to laryngeal papillomatosis in A 1 year old child. Int J Pediatr Otorhinolaryngol. 2020 Aug 29;138:110335 Authors: Samuel HT, Varghese L, Kurien R, Thomas M Abstract Inverted papillomas are rare tumors in the pediatric population and have not been reported in children less than two years. These tumors may produce respiratory distress in patients, particularly...
Wed Sep 09, 2020 13:48
Related Articles Therapy-related chronic myeloid leukemia in a patient receiving peptide receptor radionuclide therapy for pancreatic neuroendocrine tumor. Cancer Rep (Hoboken). 2020 Sep 07;:e1282 Authors: Kucukyurt S, Yagiz Ozogul Y, Ercaliskan A, Kabasakal L, Eskazan AE Abstract BACKGROUND: Therapy-related leukemia is a well-recognized clinical syndrome. Peptide receptor radionuclide therapy (PRRT) is a modern therapeutic approach using radionuclide...
Wed Sep 09, 2020 13:48
Related Articles Cervical cancer in pregnancy. Klin Onkol. 2020;33(4):268-273 Authors: Nocarová L, Ondruš D Abstract BACKGROUND: Cervical cancer is one of the most frequent cancers in pregnant women, despite this combination being a rare condition. More than 70% of cases are dia-gnosed in early stages and its treatment can be postponed after the delivery. Invasive cancer dia-gnosis in pregnancy is difficult for a patient, her family and doctors....
Wed Sep 09, 2020 13:48
Related Articles Ovarian microcystic stromal tumor with significant bizarre nuclei: A case report. Medicine (Baltimore). 2020 Aug 21;99(34):e21841 Authors: He Y, Xu L, Feng M, Wang W Abstract RATIONALE: Ovarian microcystic stromal tumor is a relatively rare tumor type, which is characterized by morphology with microcyst structure, solid cellular areas, and hyalinized fibrous stroma. The most reported tumors were stage I with good prognosis....
Wed Sep 09, 2020 13:48
Related Articles OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation. Nat Commun. 2020 08 17;11(1):4116 Authors: Sharanek A, Burban A, Laaper M, Heckel E, Joyal JS, Soleimani VD, Jahani-Asl A Abstract Glioblastoma contains a rare population of self-renewing brain tumor stem cells (BTSCs) which are endowed with properties to proliferate, spur the growth of new tumors, and at the same time,...
Wed Sep 09, 2020 13:48
Related Articles Cardiac Lymphoma Presenting with Recurrent STEMI. Methodist Debakey Cardiovasc J. 2020 Apr-Jun;16(2):158-161 Authors: Raza M, Ikram S, Williams N, Otero D, Barry N, Kelsey N, Kahlon T, Singh V Abstract The incidence of primary cardiac tumors is exceedingly rare, whereas secondary cardiac tumors are more common in the global population. Cardiac involvement is seen in approximately 18% of patients with non-Hodgkin's lymphoma...
Wed Sep 09, 2020 13:48
Related Articles The Neurofibromatoses. Dtsch Arztebl Int. 2020 May 15;117(20):354-360 Authors: Farschtschi S, Mautner VF, McLean ACL, Schulz A, Friedrich RE, Rosahl SK Abstract BACKGROUND: Neurofibromatosis of types 1 and 2 (NF1, NF2) and schwannomatosis are the diseases that make up the neurofibromatosis spectrum. With respective incidences of 1 in 3000, 1 in 33 000, and 1 in 60 000 births, they form part of the group of rare tumor-suppressor...
Wed Sep 09, 2020 13:48
Related Articles Multifocal tuberculosis simulating a cancer-a case report. BMC Infect Dis. 2020 Jul 10;20(1):495 Authors: Wang C, Luan Y, Liu S, Zhao M, Zhang H, Li W, Li Z, Hu X, Peng L Abstract BACKGROUND: Tuberculosis is a disease that may affect any organ of the body. Multifocal tuberculosis involving multiple systems with associated symptoms are rare, which makes the diagnosis challenging. Distinguishing multifocal tuberculosis from...
Wed Sep 09, 2020 13:48
Related Articles Monogenic and polygenic inheritance become instruments for clonal selection. Nature. 2020 08;584(7819):136-141 Authors: Loh PR, Genovese G, McCarroll SA Abstract Clonally expanded blood cells that contain somatic mutations (clonal haematopoiesis) are commonly acquired with age and increase the risk of blood cancer1-9. The blood clones identified so far contain diverse large-scale mosaic chromosomal alterations (deletions, duplications...
Wed Sep 09, 2020 13:48
Related Articles Comparison of mutation profile between primary phyllodes tumors of the breast and their paired local recurrences. Pol J Pathol. 2020;71(1):7-12 Authors: Mitus J, Adamczyk A, Majchrzyk K, Kowalik A, Ryś J, Niemiec J Abstract Phyllodes tumor of the breast (PTB) is a rare neoplasm and accounts for 0.2-2.0% of breast cancer in women. Histopathological diagnosis of the tumor is difficult, and histological features do not always...
Wed Sep 09, 2020 13:48
Related Articles Rare causes of hypoglycemia in adults. Ann Endocrinol (Paris). 2020 Jun;81(2-3):110-117 Authors: Douillard C, Jannin A, Vantyghem MC Abstract Hypoglycemia is defined by a low blood glucose level associated to clinical symptoms. Hypoglycemia may be related to treatment of diabetes, but also to drugs, alcohol, critical illness, cortisol insufficiency including hypopituitarism, insulinoma, bariatric or gastric surgery, pancreas...
Wed Sep 09, 2020 13:48
Related Articles Multiple Large-Size Cystic Cerebral Cavernomas. World Neurosurg. 2020 07;139:410-414 Authors: Efe IE, Aydin OU, Alabulut A, Celik O, Aydin K Abstract BACKGROUND: Cerebral cavernomas are vascular malformations characterized by networks of abnormally dilated capillaries. They typically present as nodules with mixed signal intensity and a surrounding hemosiderin rim on magnetic resonance imaging. They may occur as multiple lesions...
Wed Sep 09, 2020 13:48
Related Articles Dural-Based Primary Central Nervous System Lymphoma with Bone Invasion. World Neurosurg. 2020 07;139:415-418 Authors: Lee SW, Jung TY, Baek HJ, Kim SK, Lee KH Abstract BACKGROUND: Primary central nervous system lymphoma (PCNSL) occurs frequently in a deep intraparenchymal location. It rarely occurs in the meninges, and bone invasion is uncommon. CASE DESCRIPTION: A 12-year-old boy was admitted to our hospital with...
Wed Sep 09, 2020 13:48
Related Articles Unusual Malignant Thoracic Cystic Lesion. World Neurosurg. 2020 07;139:423-425 Authors: Sharma M, Madrigal FC, Altstadt T Abstract Malignant cystic lesions in the spine are rare. In this report, we present a 65-year-old man who presented with imbalance on walking of 1-week duration with intact motor examination. Magnetic resonance imaging of the thoracic spine showed large expansile, T2-hyperintense mass involving T8 vertebral...
Wed Sep 09, 2020 13:48
Related Articles Solitary Metastatic Melanoma of the Pituitary Gland: Report of Two Cases and Literature Review. World Neurosurg. 2020 07;139:378-381 Authors: Mattogno PP, Giordano M, D'Alessandris QG, Ktari O, Giampietro A, Rigante M, Gessi M, Olivi A, Lauretti L Abstract BACKGROUND: Pituitary melanoma metastases (PMMs) are extremely rare and only a few cases are reported in the literature. PMMs can grow rapidly and present local invasiveness,...
Wed Sep 09, 2020 13:48
Related Articles Initial Report of an Intradural Extramedullary Metastasis of a Pancreatic Neuroendocrine Tumor to the Cervical Spine: A Case Report and Review of the Literature. World Neurosurg. 2020 07;139:355-360 Authors: Saway BF, Fayed I, Dowlati E, Derakhshandeh R, Sandhu FA Abstract BACKGROUND: Pancreatic neuroendocrine tumors (pNETs) are known to frequently metastasize to the liver and lymphatics; however, metastasis to the spine is...
Wed Sep 09, 2020 13:48
Related Articles Mobile Myxopapillary Ependymoma with Associated Filum Terminale Cyst. World Neurosurg. 2020 07;139:337-342 Authors: Mastorakos P, Pomeraniec IJ, Shah S, Shoushtarizadeh A, Quezado MM, Heiss J Abstract BACKGROUND: Intradural ependymal cysts are benign, fluid-filled cysts usually situated along the ventral surface of the spinal cord. There are previous reports of 19 intradural cysts in the literature, including one cyst of the...
Wed Sep 09, 2020 13:48
Related Articles Course of cervical intraepithelial neoplasia diagnosed during pregnancy. Arch Gynecol Obstet. 2020 06;301(6):1503-1512 Authors: Grimm D, Lang I, Prieske K, Jaeger A, Müller V, Kuerti S, Burandt E, Lezius S, Schmalfeldt B, Woelber L Abstract PURPOSE: Management of high-grade cervical intraepithelial neoplasia [CIN grade 2 or 3 (CIN2-3)] diagnosed during pregnancy is controversial. Monitoring with colposcopy and cytology every...
Wed Sep 09, 2020 13:48
Related Articles Surgical Resection of Solitary Bone Plasmacytoma of Atlas and Reconstruction with 3-Dimensional-Printed Titanium Patient-Specific Implant. World Neurosurg. 2020 07;139:322-329 Authors: Li Y, Zheng G, Liu T, Liang Y, Huang J, Liu X, Huang J, Cheng Z, Lu S, Huang L Abstract BACKGROUND: Solitary plasmacytoma of bone (SPB) is a rare malignancy of localized osseous lesion consisting of neoplastic monoclonal plasma cells. Recommended...
Wed Sep 09, 2020 13:48
Related Articles Adult cavernous haemangioma of the vocal cords with a unique presentation of acute respiratory distress: a case report. Ann R Coll Surg Engl. 2020 Sep;102(7):e152-e154 Authors: Rafie A, Jolly K, Darr A, Thompson S Abstract Laryngeal haemangiomas can commonly be seen in children, and first-line treatment is usually propranolol. However, in adults, cavernous haemangioma of the vocal cord(s) is an extremely rare condition - with...
Wed Sep 09, 2020 13:48
Related Articles Soft-tissue sarcoma in adults: An update on the current state of histiotype-specific management in an era of personalized medicine. CA Cancer J Clin. 2020 05;70(3):200-229 Authors: Gamboa AC, Gronchi A, Cardona K Abstract Soft-tissue sarcomas (STS) are rare tumors that account for 1% of all adult malignancies, with over 100 different histologic subtypes occurring predominately in the trunk, extremity, and retroperitoneum. This...
Wed Sep 09, 2020 13:48
Related Articles [Symptomatic testicular metastasis of acinar adenocarcinoma of the prostate]. Urologe A. 2020 Sep;59(9):1092-1094 Authors: Kollitsch L, Hamann C, Knüpfer S, Meyer D, Kneissl P, Jüttner E, Osmonov D Abstract We report about the rare occurrence of symptomatic testicular metastasis of an acinar adenocarcinoma of the prostate. Testicular metastases are usually incidentally detected in patients treated with bilateral orchiectomy...
Wed Sep 09, 2020 13:48
Related Articles Polyomavirus-driven Merkel cell carcinoma: Prospects for therapeutic vaccine development. Mol Carcinog. 2020 07;59(7):807-821 Authors: Tabachnick-Cherny S, Pulliam T, Church C, Koelle DM, Nghiem P Abstract Great strides have been made in cancer immunotherapy including the breakthrough successes of anti-PD-(L)1 checkpoint inhibitors. In Merkel cell carcinoma (MCC), a rare and aggressive skin cancer, PD-(L)1 blockade is highly...
Wed Sep 09, 2020 13:48
Related Articles Prevalence and progression of carbohydrate disorders in patients with pheochromocytoma/paraganglioma: retrospective single-center study. Ann Endocrinol (Paris). 2020 Feb;81(1):3-10 Authors: Elenkova A, Matrozova J, Vasilev V, Robeva R, Zacharieva S Abstract BACKGROUND: Carbohydrate disorders are the most frequent metabolic disorders, affecting a significant proportion of patients with pheochromocytoma. OBJECTIVE:...
Wed Sep 09, 2020 13:48
Related Articles Febrile Neutropenia in a Patient with Non-Small Cell Lung Cancer Treated with the Immune-Checkpoint Inhibitor Nivolumab. Am J Case Rep. 2020 Feb 04;21:e920809 Authors: Hisamatsu Y, Morinaga R, Watanabe E, Ohtani S, Shirao K Abstract <strong>BACKGROUND</strong> Nivolumab is a human IgG4 monoclonal antibody against human programmed cell death 1 (PD-1). It has demonstrated efficacy against metastatic non-small cell...
Wed Sep 09, 2020 13:48
Related Articles Paraneoplastic Leukemoid Reaction in Gastroesophageal Junction Adenocarcinoma: A Case Report. Am J Case Rep. 2020 Jan 31;21:e919596 Authors: Chang KW, Kwok LL, Rana MK, Patel S, Birris T Abstract BACKGROUND The presence of leukocytosis associated with non-hematological malignancy after ruling out other causes is defined as paraneoplastic leukemoid reaction (PLR). PLR is a rare manifestation of various solid tumors. It is associated...
Wed Sep 09, 2020 13:48
Related Articles Phenytoin Seizure Prophylaxis Therapy Resulting in Severe Thrombocytopenia After Brain Tumor Debulking Surgery. Am J Case Rep. 2020 Jan 30;21:e919828 Authors: Al Ghamdi RM, Turkistani AN, Ben Ali H Abstract BACKGROUND Phenytoin is an antiepileptic drug that is usually prescribed as a prevention treatment for tonic-clonic seizures or partial seizures, and as a prophylaxis for the neurosurgical related seizures. Phenytoin administration...
Wed Sep 09, 2020 13:48
Abstract Purpose/objective(s) Tyrosine kinase inhibitors (TKIs) are commonly employed for patients with brain metastases from lung cancer and specific driver mutations. We sought to identify the correlation between intracranial tumor burden and outcomes in patients with brain metastases treated with TKIs. Materials/methods We identified and retrospectively...
Wed Sep 09, 2020 03:00
Background and Aims. Treatment options for radiation-induced intestinal injury (RIII) are limited. Crocetin has been demonstrated to exert antioxidant, antiapoptotic, and anti-inflammatory effects on various diseases. Here, we investigate the effects of crocetin on RIII in vitro. Materials and Method. IEC-6 cells exposed to 10 Gy of radiation were treated with different doses of crocetin (0, 0.1, 1, 10, and 100 μM), and cell viability was assessed by CCK-8. The levels of superoxide dismutase (SOD),...
Wed Sep 09, 2020 08:20
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN01522A, MinireviewLing Yun Qin, Hong Ling Zhang, Wei Gong, Hong Qun Luo, Nianbing Li, Bang Lin LiLayered nanostructures (LNs), including two-dimensional nanosheets, nanoflakes, and planar nanodots, own large surface-to-volume ratios, unique optical properties, and desired interfacial activities. It is highly promising that LNs can serve as...The content of this RSS Feed (c) The Royal Society of Chemistry
Wed Sep 09, 2020 02:00
Abstract We are in the midst of the global pandemic. Though acute respiratory coronavirus (SARS-COV2) that leads to COVID-19 infects people of all ages, severe symptoms and mortality occur disproportionately in older adults. Geroscience interventions that target biological aging could decrease risk across multiple age-related diseases and improve outcomes in response to infectious disease. This offers hope for a new host-directed therapeutic approach that could (i) improve outcomes...
Wed Sep 09, 2020 03:00
Abstract Racial, ethnic, sexual, and gender minorities are more likely to report challenges with oncology provider communication and quality of care. The Together-Equitable-Accessible-Meaningful (TEAM) training was developed to improve health equity across cancer care organizations by guiding teams of interprofessional learners through planning and implementation of quality improvements to advance equitable, accessible, and patient-centered cancer care. This study compared changes...
Wed Sep 09, 2020 03:00
Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN00949K, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Philipp H. Egbers, Tilmann Harder, Boris P. Koch, Jan TebbenThe study of bacterial metal chelators, so called siderophores, requires robust analytical methods that selectively target and extract strong iron-binding compounds from complex samples containing a plethora of organic molecules.To cite this article before page numbers...
Wed Sep 09, 2020 02:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN01300E, Critical ReviewRuyuan Wang, Ningning Yue, Aiping FanChemiluminescent (CL) analysis is a trace analytical method that possesses advantages including high sensitivity, wide linear range, easy operation, and simple instrument. With the development of nanotechnology, many nanomaterials (NMs)-enhanced...The content of this RSS Feed (c) The Royal Society of Chemistry
Wed Sep 09, 2020 02:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου