Tooth extraction without discontinuation of oral antithrombotic treatment: a prospective study.

Tooth extraction without discontinuation of oral antithrombotic treatment: a prospective study.:

Abstract

Objective

To identify which variable, among those related to surgeries, to patients or to antithrombotic treatments, could be considered as a bleeding indicator, and to analyze effectiveness of the local hemostatic protocols used, incidence of bleeding and healing index, depending on the number of extracted teeth and patient antithrombotic treatment.

Methods

Patients who underwent tooth extractions without interruption or reduction of antithrombotic treatment were prospectively followed. The exact two‐tailed Fisher test was used to investigate the relationship between presence/absence of bleeding and type of haemostatic material. The effect of variables on the probability of bleeding and healing index was assessed by means of a multivariate logistic regression.

Results

Two hundred and fifty‐four procedures were analyzed. The incidence of bleeding was 15.75%. Severe bleeding occurred in only 6 patients (2.34%). The number of involved dental quadrants and pre‐surgical antibiotic treatments were found to be positively related with bleeding. The use of vasoconstrictors during surgery resulted in a reduction of healing index scores.

Conclusions

Tooth extractions in patients on antithrombotic treatment were found to be free from significant bleeding although the involvement of more than 1 quadrant in the same procedure should be avoided.