Related ArticlesAlcohol-mediated behaviours and the gut-brain axis; with focus on glucagon-like peptide-1. Brain Res. 2019 Nov 21;:146562 Authors: Elisabet J Abstract The neurochemical mechanisms that regulate development of alcohol use disorder (AUD) are complex, and gut-brain peptides were recently pinpointed as novel modulators. Gut-brain peptides, such as glucagon-like peptide-1 (GLP-1), are well known for their ability to regulate food intake and...
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Related ArticlesRe: Pre-treatment wait time for head and neck cancer patients in Western Australia: description of a new metric and examination of predictive factors. ANZ J Surg. 2019 Nov;89(11):1525-1526 Authors: Venchiarutti RL, Clark JR, Palme CE, Young JM PMID: 31760696 [PubMed - in process]
Related ArticlesMulti-atlas segmentation of the facial nerve from clinical CT for virtual reality simulators. Int J Comput Assist Radiol Surg. 2019 Nov 23;: Authors: Gare BM, Hudson T, Rohani SA, Allen DG, Agrawal SK, Ladak HM Abstract PURPOSE: To create a novel, multi-atlas-based segmentation algorithm of the facial nerve (FN) requiring minimal user intervention that could be easily deployed into an existing open-source toolkit. Specifically, the mastoid,...
Related ArticlesAssessment of condylar volume and ramus height in JIA patients with unilateral and bilateral TMJ involvement: retrospective case-control study. Clin Oral Investig. 2019 Nov 23;: Authors: Farronato M, Cavagnetto D, Abate A, Cressoni P, Fama A, Maspero C Abstract OBJECTIVES: The objectives of the study are to analyze volumetric differences of condylar volumes in patients with unilateral and bilateral JIA and to compare results with control...
Related ArticlesA rare case of benign teratoma of the facial fronto-temporal region in adult male. Pol Merkur Lekarski. 2019 Oct 29;47(280):150-152 Authors: Kisiel MA, Chmielewski R, Bartoszewicz R Abstract Teratoma is a germ cell neoplasm composed of tissue derived from at least two of three blastodermic embryonic layers (ectoderm, mesoderm and endoderm). The incidence of teratoma in the head and neck region is rare, in particularly in adults. ...
Related ArticlesPublishing trends in velopharyngeal insufficiency. Int J Pediatr Otorhinolaryngol. 2019 Oct 31;129:109761 Authors: Poff C, Horton J, Boerner R, Marston A, Nguyen SA, White DR Abstract OBJECTIVE: This study seeks to describe publishing trends for VPI over a 33-year span with regard to treating specialty, methods of assessment, related diagnoses, and methods of treatment for each specialty. METHODS: A PubMed search was performed...
Related ArticlesRelation of public health staffing to follow-up after newborn hearing screening in three health districts in Georgia, 2009-2015. Int J Pediatr Otorhinolaryngol. 2019 Nov 18;129:109784 Authors: Al-Mulki K, Todd NW Abstract OBJECTIVE: To describe the association, or non-association, of public health district staffing (specifically, Early Hearing Detection and Intervention [EHDI] coordinator/navigator) and loss to follow-up in newborns who...
Related ArticlesModeling the characteristics of spontaneous otoacoustic emissions in lizards. Hear Res. 2019 Nov 15;385:107840 Authors: Wit HP, Manley GA, van Dijk P PMID: 31760263 [PubMed - as supplied by publisher]
Related ArticlesVascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear. Hear Res. 2019 Nov 08;385:107839 Authors: Wan L, Lovett M, Warchol ME, Stone JS Abstract Hair cells in the auditory organ of the vertebrate inner ear are the sensory receptors that convert acoustic stimuli into electrical signals that are conveyed along the auditory nerve to the brainstem. Hair cells are highly susceptible to...
Related ArticlesDownregulation of microR-147b represses the proliferation and invasion of thyroid carcinoma cells by inhibiting Wnt/β-catenin signaling via targeting SOX15. Mol Cell Endocrinol. 2019 Nov 21;:110662 Authors: Xu C, Liu J, Yao X, Bai Y, Zhao Q, Zhao R, Kou B, Li H, Han P, Wang X, Guo L, Zheng Z, Zhang S Abstract microRNA-147b (miR-147b) is a newly identified tumor-related miRNA that is dysregulated in multiple cancer types. Yet, the role...
Related ArticlesUnmasking Anxiety: A Qualitative Investigation of Health Professionals; Perspectives of Mask Anxiety in Head and Neck Cancer. J Med Imaging Radiat Sci. 2019 Nov 20;: Authors: Klug N, Butow PN, Burns M, Dhillon HM, Sundaresan P Abstract BACKGROUND: To ensure precision of treatment, patients requiring radiation therapy for treatment of head and neck cancer (HNC) are stabilized using a fitted thermoplastic immobilization mask. Despite evidence...
Related ArticlesFluoroscopic-guided nasogastric tube placement in patients with advanced head and neck cancers. J Formos Med Assoc. 2019 Nov 21;: Authors: Chen PT, Lee BC, Huang YC, Chang YC, Tzeng HL, Liu KL Abstract BACKGROUND/PURPOSE: Enteral feeding, mainly by using a nasogastric tube (NGT), is generally favored over parenteral supplementation in head and neck cancer (HNC) patients with dysphagia. However, the placement of a NGT, either blindly or...
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Related ArticlesPhysiology of Myelinated Nerve Conduction and Pathophysiology of Demyelination. Adv Exp Med Biol. 2019;1190:85-106 Authors: Franssen H Abstract Nerve conduction in myelinated axons is a fascinating subject due to the intricate structure and complex properties of the axon and its relation to the equally complex Schwann cells surrounding it. This chapter first deals with normal functional aspects of voltage-gated ion channels in the axon...
Related ArticlesDHEAS prevents pro-metastatic and proliferative effects of 17ß-estradiol on MCF-7 breast cancer cells. Biochim Biophys Acta Mol Cell Res. 2019 Nov 21;:118600 Authors: Upmanyu N, Bulldan A, Failing K, Scheiner-Bobis G Abstract It is generally assumed that circulating dehydroepiandrosterone sulfate (DHEAS) can be desulfated and further metabolized to estrogen, which is of concern for all patients with estrogen-responsive breast cancer....
Related ArticlesEffect of ischemic preconditioning and a Kv7 channel blocker on cardiac ischemia-reperfusion injury in rats. Eur J Pharmacol. 2019 Nov 21;:172820 Authors: Corydon KK, Matchkov V, Fais R, Abramochkin D, Hedegaard ER, Comerma-Steffensen S, Simonsen U Abstract Recently, we found cardioprotective effects of ischemic preconditioning (IPC), and from a blocker of KCNQ voltage-gated K+ channels (KV7), XE991 (10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone),...
Related ArticlesTolerance to cadmium toxicity and phytoremediation potential of three Brassica rapa CAX1a TILLING mutants. Ecotoxicol Environ Saf. 2019 Nov 20;:109961 Authors: Navarro-León E, Ruiz JM, Albacete A, Blasco B Abstract Cadmium (Cd) is one of the most toxic heavy metals that reduces crop productivity and is a threat to all the food chain including human health. Phytoremediation is an environmentally friendly strategy to clean up soil contaminated...
Related ArticlesLeydig cell tumorigenesis - implication of G-protein coupled membrane estrogen receptor, peroxisome proliferator-activated receptor and xenoestrogen exposure. In vivo and in vitro appraisal. Tissue Cell. 2019 Dec;61:51-60 Authors: Gorowska-Wojtowicz E, Duliban M, Kudrycka M, Dutka P, Pawlicki P, Milon A, Zarzycka M, Placha W, Kotula-Balak M, Ptak A, Wolski JK, Bilinska B Abstract The etiology and molecular characteristics of Leydig cell...
Related ArticlesPrevalence of Human Papilloma Virus Sub Genotypes following Head and Neck Squamous Cell Carcinomas in Asian Continent, A Systematic Review Article. Asian Pac J Cancer Prev. 2019 Nov 01;20(11):3269-3277 Authors: Bukhari N, Joseph JP, Hussain SS, Khan MA, Wakim MJY, Yahya EB, Arif A, Saleem A, Sharif N Abstract OBJECTIVES: In current era of blue brain intelligence and technology access at ease, standardization of disease etiology demands...
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Related ArticlesSevere displaced fracture of the coccyx or sacrococcygeal junction causes trauma to the thecal sac: Author's reply to "Letter to editor: Cerebrospinal fluid leak after fracture of the sacrum or coccyx." Spine J. 2019 Dec;19(12):2045 Authors: Cawley DT PMID: 31759439 [PubMed - in process]
Related ArticlesCerebrospinal fluid leak after fracture of the sacrum or coccyx. Spine J. 2019 Dec;19(12):2044 Authors: Foye PM, Singh R, Tangri V PMID: 31759438 [PubMed - in process]
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Related ArticlesGiant Symptomatic Meningocele as a Delayed, Adult Complication of Lipomyelomeningocele. World Neurosurg. 2019 Nov 21;: Authors: North RY, Verla T, Bartlett E, Reece E, Weiner HL, Ropper AE Abstract BACKGROUND: An expanding cohort of spina bifida patients live well into adulthood and pose complex management challenges due to unique combinations of adult health issues overlying congenital problems. CASE DESCRIPTION: We present...
Related ArticlesFlow Diversion for Treatment of Partially Thrombosed Aneurysms: A Multicenter Cohort. World Neurosurg. 2019 Nov 21;: Authors: Foreman PM, Salem MM, Griessenauer CJ, Dmytriw AA, Parra-Farinas C, Nicholson P, Limbucci N, Kühn AL, Puri AS, Renieri L, Nappini S, Kicielinski KP, Bugarini A, Pereira VM, Marotta TR, Schirmer CM, Ogilvy CS, Thomas AJ Abstract OBJECTIVE: Partially thrombosed intracranial aneurysms (PTIA) represent a unique subset...
Related ArticlesHow to approach a brain in an atraumatic fashion - how early cortical stimulation paved the way to neurosurgery as we understand today. World Neurosurg. 2019 Nov 21;: Authors: Keiner D PMID: 31760187 [PubMed - as supplied by publisher]
Related ArticlesNon-discogenic sciatica: what clinical examination and imaging can tell us? World Neurosurg. 2019 Nov 21;: Authors: Guedes F, Brown RS, Lourenço Torrão-Júnior FJ, Siquara-de-Sousa AC, Pires Amorim RM Abstract OBJECTIVE: Lesions affecting the sciatic nerve (SN) can mimic lumbar radiculopathy. In patients presenting with sciatica, approximately 10% have a non-discogenic etiology. Through neurological examination and imaging, it may be possible...
Related ArticlesFactors predicting de Novo formation of fistulas after dural fistula embolization using venous sinus balloon protection. World Neurosurg. 2019 Nov 21;: Authors: Li JN, Li Q, Fang YB, Huang QH, Hong B, Zhao R, Xu Y, Liu JM Abstract OBJECT: Endovascular embolization with transvenous sinus preservation using balloon is at present the preferred modality for DAVFs involving venous sinuses (sagittal, transvers and sigmoid) with potential drainage...
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Related ArticlesThe sacral screw placement depending on morphological and anatomical peculiarities. Surg Radiol Anat. 2019 Nov 23;: Authors: Meyer C, Pfannebecker P, Siewe J, Grevenstein D, Bredow J, Eysel P, Scheyerer MJ Abstract PURPOSE: Various pathologies of the lumbosacral junction require fusion of the L5/S1 segment. However, pseudarthroses, which often come along with sacral screw loosening, are problematic. The aim of the present investigation...
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Related ArticlesLong-Term Outcomes After One-Anastomosis Gastric Bypass (OAGB) in Morbidly Obese Patients. Obes Surg. 2019 Nov 23;: Authors: Neuberg M, Blanchet MC, Gignoux B, Frering V Abstract BACKGROUND: One-anastomosis gastric bypass (OAGB) has gradually gained in popularity. Evidence of the validity of the technique and the quality of life in the longer term is scarce. The aim of this study was to retrospectively evaluate the longitudinal (≥ 5 years)...
Related ArticlesSafety of Continuous Postoperative Pulse Oximetry Monitoring Without Obstructive Sleep Apnea Screening in > 5000 Patients Undergoing Bariatric Surgery. Obes Surg. 2019 Nov 23;: Authors: van Veldhuisen SL, Arslan I, Deden LN, Aarts EO, Hazebroek EJ Abstract INTRODUCTION: Obstructive sleep apnea (OSA) is common but often undiagnosed in obese patients undergoing bariatric surgery, and is associated with increased risk of cardiopulmonary...
Related ArticlesComorbidities As Risk Factors for Rheumatoid Arthritis and Their Accrual After Diagnosis. Mayo Clin Proc. 2019 Nov 01;: Authors: Kronzer VL, Crowson CS, Sparks JA, Myasoedova E, Davis JM Abstract OBJECTIVE: To determine the prevalence of comorbidities in rheumatoid arthritis (RA), discover which comorbidities might predispose to developing RA, and identify which comorbidities are more likely to develop after RA. PATIENTS AND...
Related ArticlesIndependent association of vitamin D and insulin resistance in obstructive sleep apnea. Ann Endocrinol (Paris). 2019 Nov 01;: Authors: Fan Z, Cao B, Long H, Feng L, Li Q, Zhang Y, Li T Abstract BACKGROUND: Vitamin D insufficiency and/or high levels of parathyroid hormone (PTH) seem to be associated with abnormal glucose metabolism, which is frequent in obstructive sleep apnea (OSA). The purpose of this study was to investigate vitamin D...
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Despite advances in resuscitation care, mortality rates following cardiac arrest (CA) remain high. Between one-quarter (in-hospital CA) and two-thirds (out of hospital CA) of patients admitted comatose to inte...
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BACKGROUND:We sought to describe adverse events associated with unplanned extubation (UE) and to explore risk factors for serious adverse events post-UE among infants who experienced UE.METHODS:Data were prospectively collected on all infants who had a UE event at a single institution over a 4-y period. Demographic information and information on outcomes were obtained retrospectively. We described the frequency of post-UE adverse events: success or failure of extubation trial if offered, rate of...
BACKGROUND:The value of ultrasound in assessing lung aeration of patients with ARDS who require venovenous extracorporeal membrane oxygenation (ECMO) has, to our knowledge, never been studied. The objective of the study was to evaluate by using ultrasound lung aeration at ECMO initiation and withdrawal in subjects with severe ARDS supported by venovenous ECMO.METHODS:Fifty subjects were included in this pilot retrospective study. The lung ultrasound aeration score (LUS) and respiratory variables...
BACKGROUND:Noninvasive ventilation (NIV) contributes to the development of pressure injury in a significant number of hospitalized patients. Pressure injuries contribute to increased length of hospital stay, pain, infection, and disfigurement. This study examined the relationship between NIV use and pressure injuries in hospitalized subjects.METHODS:We retrospectively reviewed all patients on NIV at a tertiary-care children's hospital over a 2-y period. We studied the relationship between the characteristics...
BACKGROUND:Obesity leads to changes in respiratory function, causing reduced lung volumes and mechanical disadvantage of the respiratory muscles. We sought to evaluate the effect of breathing exercises using devices that impose linear and nonlinear load on reversing diaphragm dysfunction and the prevalence of atelectasis after bariatric surgery.METHODS:This was a blind randomized clinical trial. Preoperatively, we assessed the subjects' maximum inspiratory pressure by measuring nasal inspiratory...
BACKGROUND:There is limited knowledge of rapid-response (RR) events and code events for children receiving home mechanical ventilation (HMV) via a tracheostomy in a non-ICU respiratory care unit. The purpose of this study was to describe the demographic and clinical factors leading to deterioration among these children and to identify the incidence and outcomes following rapid-response and code events.METHODS:A retrospective review was conducted on hospitalized HMV children who had RR/code events...
BACKGROUND:Expiratory flow limitation (EFL) is a key physiological abnormality in COPD. Comparing tidal-to-maximum flow-volume (F-V) loops is a simple and widely available method to assess EFL in patients with COPD. We aimed to investigate whether subjects with COPD showing significant resting tidal F-V enveloping (ie, > 50% tidal volume) would present with higher exertional operating lung volumes, which would lead to greater burden of dyspnea and poorer exercise tolerance compared to their counterparts.METHODS:37...
BACKGROUND:Early identification of noninvasive ventilation (NIV) outcome predictors in patients with COPD who are experiencing acute hypercapnic respiratory failure consequent to exacerbation or pneumonia is a critical issue. The primary aim of this study was to investigate the feasibility of performing diaphragmatic ultrasound for excursion, thickness, and thickening fraction in highly dyspneic subjects with COPD admitted to the emergency department for exacerbation or pneumonia, before starting...
BACKGROUND:A new holding chamber was designed to be used with a vibrating mesh nebulizer to increase the total inhalable dose for patients. It facilitates intermittent and continuous nebulization as well as the optional supply of supplemental oxygen via a T-piece with a mouthpiece adapter. This study aimed to evaluate the effect of oxygen introduction in the new holding chamber on aerosol delivery using a vibrating mesh nebulizer.METHODS:The study was divided into 2 parts. First, the total inhalable...
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