Nature Communications, Published online: 25 November 2019; doi:10.1038/s41467-019-13358-0Single channel detection methods often suffer from false positives when analysing biological samples. Here, the authors report on the development of a three-channel detection device for measuring hydrogen sulphide in serum and demonstrate application in an in vivo model.
Mon Nov 25, 2019 02:00
Nature Communications, Published online: 25 November 2019; doi:10.1038/s41467-019-13355-3Repetitive sequences in complex eukaryote genomes can cause fragmented assemblies with incomplete gene sequences and unanchored or mispositioned contigs. Here, the authors report HERA, a method to improve genome assemblies by efficiently resolving repeats using single-molecule sequencing data.
Mon Nov 25, 2019 02:00
Nature Communications, Published online: 25 November 2019; doi:10.1038/s41467-019-13317-9Several functions have been proposed for m6A in RNA metabolism, yet little is known regarding the specific functions of individual m6A readers. Here, the authors observe that the m6A reader YTHDC2 — which contains an RNA helicase domain — acts on the coding region to promotes mRNA translation by resolving secondary structures.
Mon Nov 25, 2019 02:00
Nature Communications, Published online: 25 November 2019; doi:10.1038/s41467-019-13136-yMetal halide perovskites possess interesting properties but their sub-bandgap absorption remains largely unexplored. Here Wei et al. employ two-photon absorption spectroscopy with time-resolved microwave conductivity technique to confirm the existence of strong spin-orbit coupling effect.
Mon Nov 25, 2019 02:00
Nature Communications, Published online: 25 November 2019; doi:10.1038/s41467-019-13259-2LncRNAs at the HOX gene locus are increased in expression in NPM1 mutant acute myeloid leukemia. In this study, the authors show that one such lncRNA, HOX3B-AS3, has a role in regulating gene transcription and protein synthesis in leukemia cells.
Mon Nov 25, 2019 02:00
Nature Communications, Published online: 25 November 2019; doi:10.1038/s41467-019-13350-8In Drosophila, dosage compensation involves a twofold transcriptional upregulation of the single male chromosome X. Here the authors show that global conformational differences are specifically present in the male X chromosome and detectable using Hi-C data, indicating that dosage compensation affects global chromosome structure.
Mon Nov 25, 2019 02:00
Nature Communications, Published online: 25 November 2019; doi:10.1038/s41467-019-13068-7Checking the quality of operations of quantum computers in a reliable and scalable way is still an open challenge. Here, the authors show how to characterise multi-qubit operations in a way that scales favourably with the system’s size, and demonstrate it on a 10-qubit ion-trap device.
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