Publication date: Available online 24 November 2019Source: International ImmunopharmacologyAuthor(s): Mokhtar Nosrati, Hassan Mohabatkar, Mandana BehbahaniAbstractThis study was aimed to introduce a novel algorithm for determining linear B- and T-cell epitopes from Crimean-Congo haemorrhagic fever virus (CCHFV) antigens. To this end, 387 approved B- and T-cell epitopes, as well as 331 non-epitope peptides from different serotypes of the virus were collected from IEDB database for generating of the...
Mon Nov 25, 2019 17:13
Publication date: Available online 24 November 2019Source: International ImmunopharmacologyAuthor(s): Shuhong Wu, Siyi Tang, Haisen Peng, Yinli Jiang, Yuehui Liu, Zhaokun Wu, Qinqin Liu, Xinhua ZhuAbstractThe CC chemokine receptor 3 (CCR3) expressed by eosinophils, mast cells and Th2 cells is closely related to allergic diseases. The objective of this study was to explore whether silencing of CCR3 with short hairpin RNAs (shRNAs) delivered by a lentiviral vector could impact the function of mast...
Mon Nov 25, 2019 17:13
Publication date: Available online 24 November 2019Source: International ImmunopharmacologyAuthor(s): Jing Xu, Yang Qin, Rui Chang, Handan Tan, Qingfeng Wang, Guannan Su, Qingfeng Cao, Aize Kijlstra, Peizeng YangAbstractTo investigate aqueous cytokine profiles in acute anterior uveitis (AAU), Fuchs′ syndrome, Vogt-Koyanagi-Harada (VKH) disease and Behcet′s disease (BD), we assayed the concentrations of 17 cytokines by multiplex immunoassay in aqueous humor (AqH) collected during cataract surgery...
Mon Nov 25, 2019 17:13
Publication date: Available online 24 November 2019Source: International ImmunopharmacologyAuthor(s): Chenfei Wang, Yunying Lu, Li Chen, Ting Gao, Qian Yang, Changqing Zhu, Yingxuan ChenAbstractTh9 cells are named after their expression of IL-9. Studies in recent years demonstrated that Th9 cells could contribute to antitumor immunity by enhancing the recruitment and activation of mast cells, natural killer cells, CD8 T cells, and dendritic cells in the tumor microenvironment. To determine whether...
Mon Nov 25, 2019 17:13
To precisely predict the clinical outcome and determine the optimal treatment options for patients with esophageal squamous cell carcinoma (ESCC) remains challenging. Prognostic models based on multiple molecular markers of tumors have been shown to have superiority over the use of single biomarkers. Our previous studies have identified the crucial role of ezrin in ESCC progression, which prompted us to hypothesize that ezrin-associated proteins contribute to the pathobiology of ESCC. Herein, we...
Mon Nov 25, 2019 17:05
Intrahepatic cholangiocarcinoma (ICC) is the second most common lethal liver cancer worldwide. Currently, despite the latest developments in genomics and transcriptomics for ICC in recent years, the molecular pathogenesis promoting ICC remains elusive, especially in regulatory mechanisms of long noncoding RNAs (lncRNAs), which acts as competing endogenous RNA (ceRNA). In order to elucidate the molecular mechanism of functional lncRNA, expression profiles of lncRNAs, microRNAs (miRNAs), and messenger...
Mon Nov 25, 2019 13:05
T-2 toxin is a trichothecene mycotoxin produced by fungi which are known to contaminate cereals, especially in wheat and corn. T-2 toxin is known to cause a range of toxic effects in humans and animals, including immunosuppression and carcinogenesis. Although the effects of T-2 toxin on condition of chickens’ spleens have been reported, there has been no systematic study of damage to the spleen of broiler chickens exposed to T-2 toxin. The purpose of the present study was to assess the effects of...
Mon Nov 25, 2019 13:05
Tazarotene-induced gene 1 (TIG1) encodes a protein that is a retinoid-regulated tumor suppressor. TIG1 is expressed in most normal tissues, and downregulation of TIG1 expression in multiple cancers is caused by promoter hypermethylation. Kazal-type serine protease inhibitor-2 (SPINK2) is a serine protease inhibitor, and the SPINK protein family has been shown to inhibit the expression of urokinase-type plasminogen activator (uPA). In addition, increased levels of uPA and the uPA receptor were observed...
Mon Nov 25, 2019 12:05
Propranolol Treatment for Infantile Hemangiomas: Short-Term Adverse Effects and Follow-Up to Age Two
Objective. To analyse the short-term adverse effects (AEs) of propranolol in the treatment of infantile hemangiomas (IHs) and their relevant factors, as well as the relationship between child growth and propranolol. Methods. A total of 506 patients with confirmed or suspected IHs were enrolled, and a total of 439 cases were included in the study. Short-term AEs were analysed using single-factor analysis and binary logistic regression. Out of 439 patients, 292 were enrolled to examine the effect of...
Mon Nov 25, 2019 12:05
Abstract Purpose The present case–control study was conducted to evaluate whether acute normovolemic hemodilution (ANH) can reduce the need for perioperative allogeneic blood transfusion (ABT) and affect the incidence of perioperative complications in free-flap reconstruction of the head and neck. Methods This single-center, retrospective, observational study...
Mon Nov 25, 2019 02:00
Publication date: Available online 24 November 2019Source: Acta HistochemicaAuthor(s): Gulistan Sanem Saribas, Candan Ozogul, Meral Tiryaki, Ferda Alpaslan Pinarli, Sevtap Hamdemir KilicAbstractAsherman’s syndrome has become a growing problem with the incidence of cesarean and endometrial surgical procedures. A surgical procedure that can damage to the basal layer of the endometrium is formed as intrauterine adhesion and can cause asherman’s syndrome. Mesenchymal stem cells (MSCs) are characterized...
Mon Nov 25, 2019 16:36
Journal of Neurosciences in Rural Practice (www.ruralneuropractice.com) is new semi-annual peer-reviewed open access journal to be published from January 2010 on behalf of the Associacion Ayuda Enfermo Neuroquirurgico. The journal would not charge the authors for submission, processing or publication of manuscripts and would provide immediate free access to all its content.September-2009
Mon Nov 25, 2019 16:27
26 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/11/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Mon Nov 25, 2019 16:00
26 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/11/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Mon Nov 25, 2019 13:59
Condition: HealthyIntervention: Other: Uni- and bilateral magnetic phrenic nerve stimulationSponsor: Swiss Federal Institute of TechnologyNot yet recruiting
Mon Nov 25, 2019 15:45
Conditions: Postoperative Pain Control; Opioid ConsumptionInterventions: Drug: Ketamine; Drug: Placebo Ketamine; Drug: Lidocaine; Drug: Placebo Lidocaine; Drug: Acetaminophen; Drug: Placebo Acetaminophen; Drug: Gabapentin; Drug: Placebo Gabapentin; Drug: Celecoxib; Drug: Placebo CelecoxibSponsor: Case Comprehensive Cancer CenterNot yet recruiting
Mon Nov 25, 2019 15:45
Condition: Pertrochanteric FractureIntervention: Other: Data extraction from medical filesSponsor: Tamas IllesRecruiting
Mon Nov 25, 2019 15:45
Related Articles[Quality of life in home-based cancer patients: A comparative study of chemotherapy administration route]. Bull Cancer. 2019 Nov 20;: Authors: Dhellemmes A, Melan C, Sordes F Abstract INTRODUCTION: Home healthcare can be totally different depending on the route of treatment: intravenous anticancer drugs involve regular contact with the health caregiver while the oral route leaves the patient completely autonomous. This cross-sectional...
Mon Nov 25, 2019 15:35
Related ArticlesA comparative evaluation of the publications of French public teaching hospitals from 2004 to 2014. Bull Cancer. 2019 Nov 20;: Authors: Blanc E, Boulieu R, Bertram D Abstract Care, teaching, and research are all priorities of the French public teaching hospitals. In 2004, the remuneration method evolved from a global endowment to a fee-for-services system, based on the use of bibliometric tools. These were used in the present study to...
Mon Nov 25, 2019 15:35
Publication date: Available online 24 November 2019Source: Brain Research BulletinAuthor(s): Luca Bors, Kinga Tóth, Estilla Zsófia Tóth, Ágnes Bajza, Attila Csorba, Krisztián Szigeti, Domokos Máthé, Gábor Perlaki, Gergely Orsi, Gábor K. Tóth, Franciska Erdő
Mon Nov 25, 2019 15:22
Publication date: Available online 25 November 2019Source: Behavioural Brain ResearchAuthor(s): Changhua Qu, Linling Xu, Jun Shen, Yaqing Li, Chujie Qu, Hao Song, Junjian ZhangAbstractBackgroundChronic cerebral hypoperfusion (CCH) is a common pathophysiological basis for Alzheimer’s Disease and vascular dementia in the early stages. It has been confirmed that blood-brain barrier (BBB) destruction is a key factor in CCH-related cognitive impairment. Here we explored the effects of an enriched environment...
Mon Nov 25, 2019 15:20
Publication date: Available online 25 November 2019Source: Behavioural Brain ResearchAuthor(s): Liang Tao, Yuanyuan Zhu, Rui Wang, Jiao Han, Yulong Ma, Hang Guo, Wenhong Tang, Lixia Zhuo, Ze Fan, Anqi Yin, Wugang Hou, Yan LiAbstractAlzheimer's disease (AD) is a chronic degenerative disease of the central nervous system and the most common dementia type in elderly people. N-myc downstream-regulated gene 2 (NDRG2), a cell stress response gene, is primarily expressed in astrocytes in mammalian brains....
Mon Nov 25, 2019 15:20
Related ArticlesIn reply to the Letter to the Editor concerning "Changes of the condylar position after modified disk repositioning: a retrospective study based on magnetic resonance imaging". Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Jun 14;: Authors: Chen X, Zheng J PMID: 31760049 [PubMed - as supplied by publisher]
Mon Nov 25, 2019 15:14
Related ArticlesPublishing trends in velopharyngeal insufficiency. Int J Pediatr Otorhinolaryngol. 2019 Oct 31;129:109761 Authors: Poff C, Horton J, Boerner R, Marston A, Nguyen SA, White DR Abstract OBJECTIVE: This study seeks to describe publishing trends for VPI over a 33-year span with regard to treating specialty, methods of assessment, related diagnoses, and methods of treatment for each specialty. METHODS: A PubMed search was performed...
Mon Nov 25, 2019 14:57
Related ArticlesVideo head impulse test in children with otitis media with effusion and dizziness. Int J Pediatr Otorhinolaryngol. 2019 Nov 18;129:109783 Authors: Tozar M, Cömert E, Şencan Z, Şimşek G, Muluk NB, Kılıç R Abstract OBJECTIVE: The objectives of the study were to evaluate the vestibular impairment in children with otitis media with effusion (OME) and dizziness by using vHIT test, and to compare their results with healthy children. ...
Mon Nov 25, 2019 14:57
Related ArticlesRelation of public health staffing to follow-up after newborn hearing screening in three health districts in Georgia, 2009-2015. Int J Pediatr Otorhinolaryngol. 2019 Nov 18;129:109784 Authors: Al-Mulki K, Todd NW Abstract OBJECTIVE: To describe the association, or non-association, of public health district staffing (specifically, Early Hearing Detection and Intervention [EHDI] coordinator/navigator) and loss to follow-up in newborns who...
Mon Nov 25, 2019 14:57
Related ArticlesEvaluation of reproducibility of the chemical solubility of dental ceramics using ISO 6872:2015. J Prosthet Dent. 2019 Nov 20;: Authors: Hawsawi RA, Miller CA, Moorehead RD, Stokes CW Abstract STATEMENT OF PROBLEM: The current chemical solubility method in the International Standards Organization (ISO) 6872 (2015) specifies only the total surface area of specimens for testing (≥30 cm2) but does not describe the morphology or geometry....
Mon Nov 25, 2019 14:47
Related ArticlesDepression, anxiety, and clinical history in Spanish-speaking American patients with psychogenic nonepileptic seizures (PNES) compared with Spanish-speaking American patients with epilepsy. Epilepsy Behav. 2019 Nov 21;102:106694 Authors: Myers L, Trobliger R, Bonafina M, Vazquez-Casals G, Lancman M, Lancman M Abstract OBJECTIVE: The objective of this study was to compare Spanish-speaking American patients with epilepsy to Spanish-speaking...
Mon Nov 25, 2019 14:45
Publication date: Available online 24 November 2019Source: Journal of Neuroscience MethodsAuthor(s): Katia Pozyuchenko, Karny Shouchane-Blum, Judith Brody, Ekaterina Lazdon, Iftach Yassur, Yael Nisgav, Dan Frenkel, Hadas Stiebel-KalishAbstractBackgroundNumerous disorders affecting the optic nerve require histological examination of whole length optic nerves and chiasm. Most methods employed to study the histopathology of the optic nerves in animal models of human diseases involve resection of a short...
Mon Nov 25, 2019 14:41
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