Antibiotics, Vol. 8, Pages 233: Novel Tetracyclines Versus Alternative Antibiotics for Treating Acute Bacterial Infection: A Meta-Analysis of Randomized Controlled Trials Antibiotics doi: 10.3390/antibiotics8040233 Authors: Lan Lin Chang Lu Lai Wang Chao This meta-analysis assessed the efficacy and safety of novel tetracyclines for treating acute bacterial infections. Data from PubMed, Web of Science, EBSCO, Cochrane databases, Ovid Medline, and Embase databases...
Antibiotics, Vol. 8, Pages 232: Er,Cr:YSGG Laser-Activation Enhances Antimicrobial and Antibiofilm Action of Low Concentrations of Sodium Hypochlorite in Root Canals Antibiotics doi: 10.3390/antibiotics8040232 Authors: Betancourt Sierra Camps-Font Arnabat-Domínguez Viñas The onset and persistence of endodontic infections due to residual biofilm after chemical disinfection promotes secondary bacterial infection. Alternative methods to disinfect operated root canals are...
Antibiotics, Vol. 8, Pages 231: An Endophytic Diaporthe apiculatum Produces Monoterpenes with Inhibitory Activity against Phytopathogenic Fungi Antibiotics doi: 10.3390/antibiotics8040231 Authors: Xiao-Yu Song Huihua Wang Fei Ren Kaiying Wang Guiming Dou Xing Lv Dong-Hui Yan Gary Strobel Volatile organic compounds (VOCs) from endophytic fungi are becoming a potential antibiotic resource. The inhibitive effects of VOCs produced by an endophytic fungus in Leucaena...
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Antioxidants, Vol. 8, Pages 579: Effect of Rosmarinic Acid and Sinapic Acid on Oxidative Stress Parameters in the Cardiac Tissue and Serum of Type 2 Diabetic Female Rats Antioxidants doi: 10.3390/antiox8120579 Authors: Zych Wojnar Borymski Szałabska Bramora Kaczmarczyk-Sedlak Cardiovascular diseases are one of the most common complications of type 2 diabetes. They are considered the leading cause of death among diabetics. One of the mechanisms underlying diabetic...
Antioxidants, Vol. 8, Pages 578: Oleuropein, a Bioactive Compound from Olea europaea L., as a Potential Preventive and Therapeutic Agent in Non-Communicable Diseases Antioxidants doi: 10.3390/antiox8120578 Authors: Chiara Nediani Jessica Ruzzolini Annalisa Romani Lido Calorini Growing scientific literature data suggest that the intake of natural bioactive compounds plays a critical role in preventing or reducing the occurrence of human chronic non-communicable diseases (NCDs)....
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Arts, Vol. 8, Pages 154: A Pathway Home: Connecting Museum Collections with Native Communities Arts doi: 10.3390/arts8040154 Authors: Chavez Lamar In 2016, the Smithsonian’s National Museum of the American Indian (NMAI) and the Poeh Cultural Center, owned and operated by the Pueblo of Pojoaque in New Mexico, begin work on a loan of 100 ceramics in NMAI’s collections to the Poeh Cultural Center. Making loans to other institutions is regular practice for NMAI. In making...
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Atmosphere, Vol. 10, Pages 736: Evaluation of A Regional Climate Model for the Eastern Nile Basin: Terrestrial and Atmospheric Water Balance Atmosphere doi: 10.3390/atmos10120736 Authors: Abdelwares Lelieveld Hadjinicolaou Zittis Wagdy Haggag The study of water balance is considered here as a way to assess the performance of regional climate models and examine model uncertainty and as an approach to understanding regional hydrology, especially interactions between...
Atmosphere, Vol. 10, Pages 735: Projections of Temperature-Attributable Deaths in Portuguese Metropolitan Areas: A Time-Series Modelling Approach Atmosphere doi: 10.3390/atmos10120735 Authors: Mónica Rodrigues Paula Santana Alfredo Rocha Climate change is now widely recognised as the greatest global threat over the coming decades. This study aimed to quantify and project the effects of climate change on future temperature-attributable mortality due to circulatory system diseases...
Atmosphere, Vol. 10, Pages 734: A Novel Approach for Water Conservation and Plume Abatement in Mechanical Draft Cooling Towers Atmosphere doi: 10.3390/atmos10120734 Authors: Weishu Wang Xuewen Ge Shifei Zhao Haonan Zheng Weihui Xu Jiatong Lv Ge Zhu While the visible plume from a cooling tower is not a pollutant, it can affect the surrounding environment. Moreover, the accompanied evaporation loss has a great potential for wastewater recovery. In the present study, a...
Atmosphere, Vol. 10, Pages 733: Correlation of Oxidative Potential with Ecotoxicological and Cytotoxicological Potential of PM10 at an Urban Background Site in Italy Atmosphere doi: 10.3390/atmos10120733 Authors: Maria Giulia Lionetto Maria Rachele Guascito Roberto Caricato Maria Elena Giordano Anna Rita De Bartolomeo Maria Pia Romano Marianna Conte Adelaide Dinoi Daniele Contini Exposure to atmospheric particulate matter (PM) has detrimental effects on health,...
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Behavioral Sciences, Vol. 9, Pages 124: Teachers’ Views on the Participation of Parents in the Transition of their Children from Kindergarten to Primary School Behavioral Sciences doi: 10.3390/bs9120124 Authors: Besi Sakellariou Internationally, a great number of researchers have pointed out the significance of school–family relationship in the process of children’s transition to primary schools. However, only recently has it been a subject of research in Greece....
Behavioral Sciences, Vol. 9, Pages 123: Do Students Really Use Internet Access for Learning in the Classroom? : Exploring Students’ Cyberslacking in an Indonesian University Behavioral Sciences doi: 10.3390/bs9120123 Authors: Simanjuntak Nawangsari Ardi University students, as ‘digital natives’, use the internet for learning in the classroom. However, the availability of internet access in the classroom becomes a challenge, because students also engage in...
Behavioral Sciences, Vol. 9, Pages 122: A Machine Learning Approach for Studying the Comorbidities of Complex Diagnoses Behavioral Sciences doi: 10.3390/bs9120122 Authors: Marina Sánchez-Rico Jesús M. Alvarado The study of diagnostic associations entails a large number of methodological problems regarding the application of machine learning algorithms, collinearity and wide variability being some of the most prominent ones. To overcome these, we propose and tested the usage of uniform...
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Beverages, Vol. 5, Pages 66: Statistical Modelization of the Descriptor “Minerality” Based on the Sensory Properties and Chemical Composition of Wine Beverages doi: 10.3390/beverages5040066 Authors: Elvira Zaldívar Santamaría David Molina Dagá Antonio T. Palacios García When speaking of “minerality” in wines, it is common to find descriptive terms in the vocabulary of wine tasters such as flint, match smoke, kerosene, rubber eraser, slate, granite, limestone,...
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Biomedicines, Vol. 7, Pages 91: Simplified Admix Archaeal Glycolipid Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Enhances Protection from Murine Melanoma Biomedicines doi: 10.3390/biomedicines7040091 Authors: Felicity C. Stark Gerard Agbayani Jagdeep K. Sandhu Bassel Akache Charis McPherson Lise Deschatelets Renu Dudani Melissa Hewitt Yimei Jia Lakshmi Krishnan Michael J. McCluskie Archaeosomes are liposomes composed of natural or synthetic...
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Biomolecules, Vol. 9, Pages 772: Effects of Post Anthesis Foliar Application of Sodium Selenite to Soybeans (Glycine max): Lipid Composition and Oil Stability Biomolecules doi: 10.3390/biom9120772 Authors: María José Escalante-Valdez Daniela Guardado-Félix Sergio O. Serna-Saldívar Daniel Barrera-Arellano Cristina Chuck-Hernández This study aimed at determining whether applying selenium to soybean plants affected composition and oil oxidative stability of the seeds. Soybean...
Biomolecules, Vol. 9, Pages 770: Design of Novel Haptens and Development of Monoclonal Antibody-Based Immunoassays for the Simultaneous Detection of Tylosin and Tilmicosin in Milk and Water Samples Biomolecules doi: 10.3390/biom9120770 Authors: Jian-Xin Huang Chan-Yuan Yao Jin-Yi Yang Zhen-Feng Li Fan He Yuan-Xin Tian Hong Wang Zhen-Lin Xu Yu-Dong Shen In this work, a monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay (icELISA) was...
Biomolecules, Vol. 9, Pages 771: Marine Invertebrate Extracts Induce Colon Cancer Cell Death via ROS-Mediated DNA Oxidative Damage and Mitochondrial Impairment Biomolecules doi: 10.3390/biom9120771 Authors: Verónica Ruiz-Torres Celia Rodríguez-Pérez María Herranz-López Beatriz Martín-García Ana-María Gómez-Caravaca David Arráez-Román Antonio Segura-Carretero Enrique Barrajón-Catalán Vicente Micol Marine compounds are a potential source of new anticancer drugs....
Biomolecules, Vol. 9, Pages 769: RKIP as an Inflammatory and Immune System Modulator: Implications in Cancer Biomolecules doi: 10.3390/biom9120769 Authors: Gabriela-Freitas Pinheiro Raquel-Cunha Cardoso-Carneiro Martinho Raf kinase inhibitor protein (RKIP), an important modulator of intracellular signalling pathways, is commonly downregulated in multiple cancers. This reduction, or loss of expression, is correlated not only with the presence of metastasis, contributing...
Biomolecules, Vol. 9, Pages 768: Identification, Classification and Screening for γ-Amino-butyric Acid Production in Lactic Acid Bacteria from Cambodian Fermented Foods Biomolecules doi: 10.3390/biom9120768 Authors: Dalin Ly Sigrid Mayrhofer I. B. Agung Yogeswara Thu-Ha Nguyen Konrad J. Domig Screening for various types of lactic acid bacteria (LAB) that form the biological agent γ-amino-butyric acid (GABA) is important to produce different kinds of GABA-containing...
Biomolecules, Vol. 9, Pages 767: Cytoproliferative and Anti-Oxidant Effects Induced by Tannic Acid in Human Embryonic Kidney (Hek-293) Cells Biomolecules doi: 10.3390/biom9120767 Authors: Pearl O. Perumal Priscilla Mhlanga Anou M. Somboro Daniel G. Amoako Hezekiel M. Khumalo Rene M. Khan Tannic acid (TA) portrays a myriad of beneficial properties and has forthwith achieved incessant significance for its cytoprotective qualities in traditional and modern-day medicine. However,...
Biomolecules, Vol. 9, Pages 766: Salivary Protein Panel to Diagnose Systolic Heart Failure Biomolecules doi: 10.3390/biom9120766 Authors: Xi Zhang Daniel Broszczak Karam Kostner Kristyan B Guppy-Coles John J Atherton Chamindie Punyadeera Screening for systolic heart failure (SHF) has been problematic. Heart failure management guidelines suggest screening for structural heart disease and SHF prevention strategies should be a top priority. We developed a multi-protein biomarker...
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Brain Sciences, Vol. 9, Pages 335: Semi-Automatic Signature-Based Segmentation Method for Quantification of Neuromelanin in Substantia Nigra Brain Sciences doi: 10.3390/brainsci9120335 Authors: Gašper Zupan Dušan Šuput Zvezdan Pirtošek Andrej Vovk In Parkinson’s disease (PD), there is a reduction of neuromelanin (NM) in the substantia nigra (SN). Manual quantification of the NM volume in the SN is unpractical and time-consuming; therefore, we aimed to quantify NM in...
Brain Sciences, Vol. 9, Pages 336: A Novel Neighbor Housing Environment Enhances Social Interaction and Rescues Cognitive Deficits from Social Isolation in Adolescence Brain Sciences doi: 10.3390/brainsci9120336 Authors: Alexander B. Pais Anthony C. Pais Gabriel Elmisurati So Hyun Park Michael F. Miles Jennifer T. Wolstenholme Adolescence is characterized by high levels of playful social interaction, cognitive development, and increased risk-taking behavior. Juvenile exposure...
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Cancers, Vol. 11, Pages 1849: The Protein Neddylation Inhibitor MLN4924 Suppresses Patient-Derived Glioblastoma Cells via Inhibition of ERK and AKT Signaling Cancers doi: 10.3390/cancers11121849 Authors: Han Shin Oh Oh Her Nam Glioblastoma is a highly aggressive and lethal brain tumor, with limited treatment options. Abnormal activation of the neddylation pathway is observed in glioblastoma, and the NEDD8-activating enzyme (NAE) inhibitor, MLN4924, was previously...
Cancers, Vol. 11, Pages 1848: The Potential Impact of Connexin 43 Expression on Bcl-2 Protein Level and Taxane Sensitivity in Head and Neck Cancers–In Vitro Studies Cancers doi: 10.3390/cancers11121848 Authors: Bianka Gurbi Diána Brauswetter Attila Varga Pál Gyulavári Kinga Pénzes József Murányi Veronika Zámbó Ede Birtalan Tibor Krenács David Laurence Becker Miklós Csala István Vályi-Nagy István Peták Kornél Dános The poor prognosis of head and...
Cancers, Vol. 11, Pages 1846: Mechanistic Signatures of Human Papillomavirus Insertions in Anal Squamous Cell Carcinomas Cancers doi: 10.3390/cancers11121846 Authors: Adeline Morel Cindy Neuzillet Maxime Wack Sonia Lameiras Sophie Vacher Marc Deloger Nicolas Servant David Veyer Hélène Péré Odette Mariani Sylvain Baulande Roman Rouzier Maud Kamal Elsy El Alam Emmanuelle Jeannot Alain Nicolas Ivan Bièche Wulfran Cacheux The role of human...
Cancers, Vol. 11, Pages 1847: Targeting Angiogenesis by Blocking the ATM–SerRS–VEGFA Pathway for UV-Induced Skin Photodamage and Melanoma Growth Cancers doi: 10.3390/cancers11121847 Authors: Yadong Song Hongyan Lu Qiong Wang Rong Xiang Retinoic acid (RA) has been widely used to protect skin from photo damage and skin carcinomas caused by solar ultraviolet (UV) irradiation, yet the mechanism remains elusive. Here, we report that all-trans retinoic acid (tRA) can directly induce...
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Cells, Vol. 8, Pages 1495: MiR-33a Controls hMSCS Osteoblast Commitment Modulating the Yap/Taz Expression Through EGFR Signaling Regulation Cells doi: 10.3390/cells8121495 Authors: Costa Carina Raimondi De Luca Bellavia Conigliaro Salamanna Alessandro Fini Giavaresi Mesenchymal stromal cells (hMSCs) display a pleiotropic function in bone regeneration. The signaling involved in osteoblast commitment is still not completely understood, and that determines...
Cells, Vol. 8, Pages 1494: Gonadotropins in Keratoconus: The Unexpected Suspects Cells doi: 10.3390/cells8121494 Authors: Karamichos Barrientez Nicholas Ma Van Bak-Nielsen Hjortdal Keratoconus (KC) is the most common ectatic corneal disease with a significant visual acuity burden. The actual burden is intangible given that KC can disrupt daily activities (reading, driving, and various career paths). Despite decades of research and clinical studies, the etiology,...
Cells, Vol. 8, Pages 1492: MicroRNAs Involved in Carcinogenesis, Prognosis, Therapeutic Resistance and Applications in Human Triple-Negative Breast Cancer Cells doi: 10.3390/cells8121492 Authors: Ding Gu Xiong Ao Cao Lin Yu Lin Cui Triple-negative breast cancer (TNBC) is the most aggressive, prevalent, and distinct subtype of breast cancer characterized by high recurrence rates and poor clinical prognosis, devoid of both predictive markers and potential...
Cells, Vol. 8, Pages 1493: Exercise Exacerbates the Transcriptional Profile of Hypoxia, Oxidative Stress and Inflammation in Rats with Adjuvant-Induced Arthritis Cells doi: 10.3390/cells8121493 Authors: González-Chávez Quiñonez-Flores Espino-Solís Vázquez-Contreras Pacheco-Tena Physical exercise (PE) is recommended for Rheumatoid Arthritis (RA), but the molecular and biological mechanisms that impact the inflammatory process and joint destruction in RA remain unknown....
Cells, Vol. 8, Pages 1491: Mesenchymal Stem/Stromal Cells Derived from Dental Tissues: A Comparative In Vitro Evaluation of Their Immunoregulatory Properties Against T cells Cells doi: 10.3390/cells8121491 Authors: María del Pilar De la Rosa-Ruiz Marco Antonio Álvarez-Pérez Víctor Adrián Cortés-Morales Alberto Monroy-García Héctor Mayani Gladis Fragoso-González Sara Caballero-Chacón Daniel Diaz Fernando Candanedo-González Juan José Montesinos Bone marrow mesenchymal...
Cells, Vol. 8, Pages 1490: PC1/3 KD Macrophages Exhibit Resistance to the Inhibitory Effect of IL-10 and a Higher TLR4 Activation Rate, Leading to an Anti-Tumoral Phenotype Cells doi: 10.3390/cells8121490 Authors: Franck Rodet Alice Capuz Bilgehan-Aybike Ozcan Rémy Le Beillan Antonella Raffo-Romero Firas Kobeissy Marie Duhamel Michel Salzet During tumorigenesis, macrophages are recruited by tumors and orientated towards a pro-tumoral phenotype. One of the main anti-tumoral...
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Foods, Vol. 8, Pages 609: Purification and Characterization of Pathogenesis Related Class 10 Panallergens Foods doi: 10.3390/foods8120609 Authors: McBride Cheng Maleki Hurlburt Oral allergy syndrome (OAS) describes an allergic reaction where an individual sensitized by pollen allergens develops symptoms after eating certain foods. OAS is caused by cross-reactivity among a class of proteins ubiquitous in plants called pathogenesis related class 10 (PR-10) proteins. The best...
Foods, Vol. 8, Pages 608: A New Sensory Approach Combined with a Text-Mining Tool to Create a Sensory Lexicon and Profile of Monovarietal Apple Juices Foods doi: 10.3390/foods8120608 Authors: Mendes da Silva Torello Marinoni Peano Roberta Giuggioli Single-cultivar juices may be a valuable way to introduce different versions of a product to the market and obtain price discrimination. To communicate a product’s value, complex characteristics incorporated by each...
Foods, Vol. 8, Pages 606: Impact of Punicalagin on the Physicochemical and Structural Properties of Wheat Flour Dough Foods doi: 10.3390/foods8120606 Authors: Hong Peng Bin Li Jing Tian The study explored punicalagin (PGN) as a wheat flour enhancer. The impact of PGN on the physicochemical and structural properties of wheat flour have been investigated. It turned out that PGN increased the formation time, stability, tensile resistance, extension, and viscoelasticity of the dough...
Foods, Vol. 8, Pages 607: Effects of Transglutaminase on the Protein Network and In Vitro Starch Digestibility of Asian Wheat Noodles Foods doi: 10.3390/foods8120607 Authors: May Sui Mei Wee Christiani Jeyakumar Henry Wheat noodles are a staple commonly consumed in Asia, but high intakes have been associated with type 2 diabetes due to its rapid starch digestibility. We hypothesised that protein network-binding via transglutaminase (TG) would form a stronger barrier encapsulating...
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Heritage, Vol. 2, Pages 2784-2801: Comparison of Aluminum Alloys from Aircraft of Four Nations Involved in the WWII Conflict Using Multiscale Analyses and Archival Study Heritage doi: 10.3390/heritage2040172 Authors: Ouissi Collaveri Sciau Olivier Brunet Aluminum alloys are very interesting witnesses of industrial and technical development. The first ever developed was Duralumin, a light metal with good mechanical properties. In the 1930s, the rise of nationalism stimulated...
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