Antioxidants, Vol. 8, Pages 586: Saffron Processing Wastes as a Bioresource of High-Value Added Compounds: Development of a Green Extraction Process for Polyphenol Recovery Using a Natural Deep Eutectic Solvent Antioxidants doi: 10.3390/antiox8120586 Authors: Achillia Lakka Spyros Grigorakis Ioanna Karageorgou Georgia Batra Olga Kaltsa Eleni Bozinou Stavros Lalas Dimitris P. Makris The current investigation was undertaken to examine saffron processing waste (SPW)...
Mon Nov 25, 2019 02:00
Antioxidants, Vol. 8, Pages 585: Exploring Target Genes Involved in the Effect of Quercetin on the Response to Oxidative Stress in Caenorhabditis elegans Antioxidants doi: 10.3390/antiox8120585 Authors: Begoña Ayuda-Durán Susana González-Manzano Antonio Miranda-Vizuete Eva Sánchez-Hernández Marta R. Romero Montserrat Dueñas Celestino Santos-Buelga Ana M. González-Paramás Quercetin is one the most abundant flavonoids in the human diet. Although it is well known that...
Mon Nov 25, 2019 02:00
Antioxidants, Vol. 8, Pages 584: Structure, Antioxidant, and Hypoglycemic Activities of Arabinoxylans Extracted by Multiple Methods from Triticale Antioxidants doi: 10.3390/antiox8120584 Authors: Hong Chen Zhuoyun Chen Yuanfang Fu Jiao Liu Siying Lin Qing Zhang Yuntao Liu Dingtao Wu Derong Lin Guoquan Han Lina Wang Wen Qin Different methods of isolating arabinoxylans (AXs) from triticale were performed to investigate the extraction methods’...
Mon Nov 25, 2019 02:00
Atmosphere, Vol. 10, Pages 740: Retrieval of Horizontal Visibility Using MODIS Data: A Deep Learning Approach Atmosphere doi: 10.3390/atmos10120740 Authors: Bo Hu Xingying Zhang Rui Sun Xianchun Zhu Horizontal visibility (HVIS) is a primary index used for assessing air quality. Although satellite images provide information regarding atmospheric aerosols, atmospheric visibility is not directly measured. In this paper, a deep learning approach is proposed to retrieve HVIS using...
Mon Nov 25, 2019 02:00
Atmosphere, Vol. 10, Pages 739: Investigation of Transport and Transformation of Tropospheric Ozone in Terrestrial Ecosystems of the Coastal Zone of Lake Baikal Atmosphere doi: 10.3390/atmos10120739 Authors: Alexander S. Zayakhanov Galina S. Zhamsueva Vadim V. Tcydypov Tumen S. Balzhanov Ayuna L. Dementeva Tamara V. Khodzher Forest ecosystems play an important role in the process of removing trace gases from the atmosphere. The purpose of this work is the experimental...
Mon Nov 25, 2019 02:00
Atmosphere, Vol. 10, Pages 738: Reconciling the Discrepancy of Post-Volcanic Cooling Estimated from Tree-Ring Reconstructions and Model Simulations over the Tibetan Plateau Atmosphere doi: 10.3390/atmos10120738 Authors: Jianping Duan Peili Wu Zhuguo Ma Volcanic eruptions are a major factor influencing global climate variability, usually with a cooling effect. The magnitudes of post-volcanic cooling from historical eruptions estimated by tree-ring reconstructions differ considerably...
Mon Nov 25, 2019 02:00
Behavioral Sciences, Vol. 9, Pages 126: Validation of a Rubric to Evaluate Open Educational Resources for Learning Behavioral Sciences doi: 10.3390/bs9120126 Authors: Anabel de la Rosa Gómez José Manuel Meza Cano Germán Alejandro Miranda Díaz Open Educational Resources (OERs) include different web formats, such as audio, video, images and text that can be modified, redistributed and used for learning about a specific topic, however, it became pertinent to create an OER evaluation...
Mon Nov 25, 2019 02:00
Biomolecules, Vol. 9, Pages 778: Artificial Neural Network (ANN) as a Tool to Reduce Human-Animal Interaction Improves Senegalese Sole Production Biomolecules doi: 10.3390/biom9120778 Authors: Martínez-Vázquez Valcarce Riesco Sanz Marco Matsuoka Robles Manipulation is usually required for biomass calculation and food estimation for optimal fish growth in production facilities. However, the advances in computer-based systems have opened a new range of applied possibilities....
Mon Nov 25, 2019 02:00
Biomolecules, Vol. 9, Pages 777: Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence Biomolecules doi: 10.3390/biom9120777 Authors: Sharifi-Rad Kobarfard Ata Ayatollahi Khosravi-Dehaghi Jugran Tomas Capanoglu Matthews Popović-Djordjević Kostić Kamiloglu Sharopov Choudhary Martins Members of the Prosopis genus are native to America, Africa and Asia, and have long...
Mon Nov 25, 2019 02:00
Biomolecules, Vol. 9, Pages 776: Combined Use of Deep Eutectic Solvents, Macroporous Resins, and Preparative Liquid Chromatography for the Isolation and Purification of Flavonoids and 20-Hydroxyecdysone from Chenopodium quinoa Willd. Biomolecules doi: 10.3390/biom9120776 Authors: Zeng Shang Zhang Wang Gu Tan : Deep eutectic solvents (DESs) were used in combination with macroporous resins to isolate and purify flavonoids and 20-hydroxyecdysone from Chenopodium quinoa...
Mon Nov 25, 2019 02:00
Brain Sciences, Vol. 9, Pages 340: Evaluation of Microglia/Macrophage Cells from Rat Striatum and Prefrontal Cortex Reveals Differential Expression of Inflammatory-Related mRNA after Methamphetamine Brain Sciences doi: 10.3390/brainsci9120340 Authors: Kays Yamamoto RNA sequencing (RNAseq) can be a powerful tool in the identification of transcriptional changes after drug treatment. RNAseq was utilized to determine expression changes in Fluorescence-activated cell sorted (FACS) CD11b/c+...
Mon Nov 25, 2019 02:00
Brain Sciences, Vol. 9, Pages 339: The Impact of Glucose on Corticospinal and Intracortical Excitability Brain Sciences doi: 10.3390/brainsci9120339 Authors: Toepp Turco Locke Nicolini Ravi Nelson Neurotransmission is highly dependent on the availability of glucose-derived energy, although it is unclear how glucose availability modulates corticospinal and intracortical excitability as assessed via transcranial magnetic stimulation (TMS). In this double-blinded placebo-controlled...
Mon Nov 25, 2019 02:00
Brain Sciences, Vol. 9, Pages 338: Functional Connectivity between the Resting-State Olfactory Network and the Hippocampus in Alzheimer’s Disease Brain Sciences doi: 10.3390/brainsci9120338 Authors: Lu Testa Jordan Elyan Kanekar Wang Eslinger Yang Zhang Karunanayaka Olfactory impairment is associated with prodromal Alzheimer’s disease (AD) and is a risk factor for the development of dementia. AD pathology is known to disrupt brain regions...
Mon Nov 25, 2019 02:00
Brain Sciences, Vol. 9, Pages 341: Erratum: Lee, J.G., et al. The Neuroprotective Effects of Melatonin: Possible Role in the Pathophysiology of Neuropsychiatric Disease. Brain Sciences 2019, 9(10), 285 Brain Sciences doi: 10.3390/brainsci9120341 Authors: Jung Goo Lee Young Sup Woo Sung Woo Park Dae-Hyun Seog Mi Kyoung Seo Won-Myong Bahk The authors wish to make an erratum to the published version of their paper [...]
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1865: Gene Therapy for Liver Cancers: Current Status from Basic to Clinics Cancers doi: 10.3390/cancers11121865 Authors: Kamimura Yokoo Abe Terai The liver is a key organ for metabolism, protein synthesis, detoxification, and endocrine function, and among liver diseases, including hepatitis, cirrhosis, malignant tumors, and congenital disease, liver cancer is one of the leading causes of cancer-related deaths worldwide. Conventional therapeutic options...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1866: Overactivation of Akt Contributes to MEK Inhibitor Primary and Acquired Resistance in Colorectal Cancer Cells Cancers doi: 10.3390/cancers11121866 Authors: Tsubaki Takeda Noguchi Jinushi Seki Morii Shimomura Imano Satou Nishida RAS and BRAF-mutated colorectal cancers are associated with resistance to chemotherapy and poor prognosis, highlighting the need for new therapeutic strategies. Although these cancers sometimes...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1867: Elevated Autotaxin and LPA Levels During Chronic Viral Hepatitis and Hepatocellular Carcinoma Associate with Systemic Immune Activation Cancers doi: 10.3390/cancers11121867 Authors: Kostadinova Shive Anthony Circulating autotaxin (ATX) is elevated in persons with liver disease, particularly in the setting of chronic hepatitis C virus (HCV) and HCV/HIV infection. It is thought that plasma ATX levels are, in part, attributable to impaired liver clearance...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1863: IL-8 Released from Human Pancreatic Cancer and Tumor-Associated Stromal Cells Signals through a CXCR2-ERK1/2 Axis to Induce Muscle Atrophy Cancers doi: 10.3390/cancers11121863 Authors: Callaway Delitto Patel Nosacka D’Lugos Delitto Deyhle Trevino Judge Judge Tumor-derived cytokines are known to drive the catabolism of host tissues, including skeletal muscle. However, our understanding of the specific cytokines that initiate...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1864: Identifying Biomarkers to Pair with Targeting Treatments within Triple Negative Breast Cancer for Improved Patient Stratification Cancers doi: 10.3390/cancers11121864 Authors: Tovey Cheang The concept of precision medicine has been around for many years and recent advances in high-throughput sequencing techniques are enabling this to become reality. Within the field of breast cancer, a number of signatures have been developed to molecularly sub-classify...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1862: Minimal Effect of Bevacizumab Treatment on Residual Vestibular Schwannomas after Partial Resection in Young Neurofibromatosis Type 2 Patients Cancers doi: 10.3390/cancers11121862 Authors: Isabel Gugel Lan Kluwe Julian Zipfel Christian Teuber Marcos Tatagiba Victor-Felix Mautner Martin Ulrich Schuhmann Florian Grimm Hearing-preserving partial resection of neurofibromatosis type 2 (NF2) associated vestibular schwannomas (VS) is a preferred...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1860: Automated Gleason Scoring and Tumor Quantification in Prostate Core Needle Biopsy Images Using Deep Neural Networks and Its Comparison with Pathologist-Based Assessment Cancers doi: 10.3390/cancers11121860 Authors: Han Suk Ryu Min-Sun Jin Jeong Hwan Park Sanghun Lee Joonyoung Cho Sangjun Oh Tae-Yeong Kwak Junwoo Isaac Woo Yechan Mun Sun Woo Kim Soohyun Hwang Su-Jin Shin Hyeyoon Chang The Gleason grading system, currently...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1861: Cachexia and Sarcopenia in Older Adults with Cancer: A Comprehensive Review Cancers doi: 10.3390/cancers11121861 Authors: Richard F. Dunne Kah Poh Loh Grant R. Williams Aminah Jatoi Karen M. Mustian Supriya G. Mohile Cancer cachexia is a syndrome characterized by weight loss with accompanying loss of muscle and/or fat mass and leads to impaired patient function and physical performance and is associated with a poor prognosis. It is prevalent...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1859: The Emerging Roles of ATP-Dependent Chromatin Remodeling Complexes in Pancreatic Cancer Cancers doi: 10.3390/cancers11121859 Authors: Nesrin Hasan Nita Ahuja Pancreatic cancer is an aggressive cancer with low survival rates. Genetic and epigenetic dysregulation has been associated with the initiation and progression of pancreatic tumors. Multiple studies have pointed to the involvement of aberrant chromatin modifications in driving tumor behavior. ATP-dependent...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1856: Incidental Use of Beta-Blockers Is Associated with Outcome of Metastatic Colorectal Cancer Patients Treated with Bevacizumab-Based Therapy: A Single-Institution Retrospective Analysis of 514 Patients Cancers doi: 10.3390/cancers11121856 Authors: Ondrej Fiala Pavel Ostasov Ondrej Sorejs Vaclav Liska Tomas Buchler Alexandr Poprach Jindrich Finek Background: Beta-adrenergic signalling plays an important role in several cancer-related processes,...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1857: Racial Differences in Immunological Landscape Modifiers Contributing to Disparity in Prostate Cancer Cancers doi: 10.3390/cancers11121857 Authors: Jeronay King Thomas Hina Mir Neeraj Kapur Shailesh Singh Prostate cancer affects African Americans disproportionately by exhibiting greater incidence, rapid disease progression, and higher mortality when compared to their Caucasian counterparts. Additionally, standard treatment interventions do not achieve...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1855: Thirty Years of Cancer Nanomedicine: Success, Frustration, and Hope Cancers doi: 10.3390/cancers11121855 Authors: Lucia Salvioni Maria Antonietta Rizzuto Jessica Armida Bertolini Laura Pandolfi Miriam Colombo Davide Prosperi Starting with the enhanced permeability and retention (EPR) effect discovery, nanomedicine has gained a crucial role in cancer treatment. The advances in the field have led to the approval of nanodrugs with improved safety...
Mon Nov 25, 2019 02:00
Cancers, Vol. 11, Pages 1858: FoxO3a as a Positive Prognostic Marker and a Therapeutic Target in Tamoxifen-Resistant Breast Cancer Cancers doi: 10.3390/cancers11121858 Authors: Michele Pellegrino Pietro Rizza Ada Donà Alessandra Nigro Elena Ricci Marco Fiorillo Ida Perrotta Marilena Lanzino Cinzia Giordano Daniela Bonofiglio Rosalinda Bruno Federica Sotgia Michael P. Lisanti Diego Sisci Catia Morelli Background: Resistance to endocrine treatments...
Mon Nov 25, 2019 02:00
Cells, Vol. 8, Pages 1510: A New Sensitive Method for the Detection of Mycoplasmas Using Fluorescence Microscopy Cells doi: 10.3390/cells8121510 Authors: Ligasová Vydržalová Buriánová Brůčková Večeřová Janošťáková Koberna Contamination of cell cultures by mycoplasmas is a very common phenomenon. As they can substantially alter cell metabolism and potentially spread to all cell cultures in laboratory, their early detection is necessary. One of the fastest and...
Mon Nov 25, 2019 02:00
Cells, Vol. 8, Pages 1511: Targeting Cyclic AMP Signalling in Hepatocellular Carcinoma Cells doi: 10.3390/cells8121511 Authors: Massimi Ragusa Cardarelli Giorgi Hepatocellular carcinoma (HCC) is a major healthcare problem worldwide, representing one of the leading causes of cancer mortality. Since there are currently no predictive biomarkers for early stage diagnosis, HCC is detected only in advanced stages and most patients die within one year, as radical tumour resection...
Mon Nov 25, 2019 02:00
Cells, Vol. 8, Pages 1509: Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine Cells doi: 10.3390/cells8121509 Authors: Nazma F. Ilahibaks Zhiyong Lei Emma A. Mol Anil K. Deshantri Linglei Jiang Raymond M. Schiffelers Pieter Vader Joost P.G. Sluijter Extracellular vesicles (EVs) are mediators of intercellular communication by transferring functional biomolecules from their originating cells to recipient...
Mon Nov 25, 2019 02:00
Cells, Vol. 8, Pages 1508: MS CD49d+CD154+ Lymphocytes Reprogram Oligodendrocytes into Immune Reactive Cells Affecting CNS Regeneration Cells doi: 10.3390/cells8121508 Authors: Paweł Piatek Magdalena Namiecinska Małgorzata Domowicz Patrycja Przygodzka Marek Wieczorek Sylwia Michlewska Natalia Lewkowicz Maciej Tarkowski Przemysław Lewkowicz The critical aspect in multiple sclerosis (MS) progression involves insufficient regeneration of CNS resulting from deficient...
Mon Nov 25, 2019 02:00
Cells, Vol. 8, Pages 1507: White Adipocyte Plasticity in Physiology and Disease Cells doi: 10.3390/cells8121507 Authors: Ewa Bielczyk-Maczynska Cellular plasticity is a transformation of a terminally differentiated cell into another cell type, which has been long known to occur in disease and regeneration. However, white adipocytes (fat cells) have only recently been observed to undergo different types of cellular plasticity. Adipocyte transdifferentiation into myofibroblasts and cancer-associated...
Mon Nov 25, 2019 02:00
Climate, Vol. 7, Pages 134: The Maturing Interdisciplinary Relationship between Human Biometeorological Aspects and Local Adaptation Processes: An Encompassing Overview Climate doi: 10.3390/cli7120134 Authors: Andre Santos Nouri Andreas Matzarakis To date, top-down approaches have played a fundamental role in expanding the comprehension of both existing, and future, climatological patterns. In liaison, the focus attributed to climatic mitigation has shifted towards the identification...
Mon Nov 25, 2019 02:00
Diagnostics, Vol. 9, Pages 202: Protein Carbonyl Content Is a Predictive Biomarker of Eccentric Left Ventricular Hypertrophy in Hemodialysis Patients Diagnostics doi: 10.3390/diagnostics9040202 Authors: Dimitrijevic Salinger Martinovic Nikolic Cvetkovic High prevalence of left ventricular hypertrophy (LVH) and elevated oxidative stress are associated with poor outcomes in chronic hemodialysis patients. Abnormal left ventriculаr geomеtry and different geometric patterns play...
Mon Nov 25, 2019 02:00
Diagnostics, Vol. 9, Pages 201: Pediatrics: An Evolving Concept for the 21st Century Diagnostics doi: 10.3390/diagnostics9040201 Authors: Consolato M. Sergi Pediatrics is rapidly evolving, and the diagnostic tools are expanding the spectrum of diagnoses that can be identified at the bedside [...]
Mon Nov 25, 2019 02:00
Diversity, Vol. 11, Pages 225: Aquatic Hemiptera in Southwest Cameroon: Biodiversity of Potential Reservoirs of Mycobacterium ulcerans and Multiple Wolbachia Sequence Types Revealed by Metagenomics Diversity doi: 10.3390/d11120225 Authors: Esemu Dong Kfusi Hartley Ndip Ndip Darby Post Makepeace Buruli ulcer (BU), caused by Mycobacterium ulcerans, is a neglected tropical disease associated with freshwater habitats. A variety of limnic organisms harbor...
Mon Nov 25, 2019 02:00
Foods, Vol. 8, Pages 618: In Vitro Antioxidant Activity of Peptides from Simulated Gastro-Intestinal Digestion Products of Cyprinus carpio haematopterus Scale Gelatin Foods doi: 10.3390/foods8120618 Authors: Xiao Chen Li He Cheng Ren A two-stage simulated gastro-intestinal (GI) digestion model (2 h pepsin treatment and subsequent 2 h pancreatin treatment at 37 °C) was used to explore the antioxidant activity of the digested products of Cyprinus carpio haematopterus...
Mon Nov 25, 2019 02:00
Foods, Vol. 8, Pages 617: Tailoring Physical and Sensory Properties of Tofu by the Addition of Jet-Milled, Superfine, Defatted Soybean Flour Foods doi: 10.3390/foods8120617 Authors: Ye-Na Kim Syahrizal Muttakin Young-Min Jung Tae-Yeong Heo Dong-Un Lee The use of defatted soybean flour (DSF) in food as a source of dietary fiber has been limited due to its rough texture and bitter taste. Our previous work indicates that superfine DSF prepared by jet milling could overcome these...
Mon Nov 25, 2019 02:00
Foods, Vol. 8, Pages 616: Effect of Creatine and Glucose on Formation of Heterocyclic Amines in Grilled Chicken Breasts Foods doi: 10.3390/foods8120616 Authors: Monika Gibis Myriam Loeffler The occurrence of heterocyclic amines (HAs) in grilled chicken breasts was investigated. All samples contained HAs, including MeIQx, PhIP, and the β-carbolines harman and norharman. In particular, PhIP was found in concentrations of 1.5–9.1 ng/g, and MeIQx was detected at very...
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