External validation of a panel of plasma microRNA biomarkers for lung cancer. Biomark Med. 2019 Nov 01;: Authors: Li J, Fang H, Jiang F, Ning Y Abstract Aim: We externally validate plasma miRNAs biomarkers for lung cancer in a large and retrospective sample set collected from a geographically distant population. Methods: Plasma samples are tested blindly to the clinical annotations by using PCR for quantitation of the four miRNAs in cohort 1 consisting...
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Related ArticlesToward a holistic view of multiscale breast cancer molecular biomarkers. Biomark Med. 2019 Oct 31;: Authors: Dai X, Zhang X, Lu P Abstract Powered by rapid technology developments, biomarkers become increasingly diverse, including those detected at genomic, transcriptomic, proteomic, metabolomic and cellular levels. While diverse sets of biomarkers have been utilized in breast cancer predisposition, diagnosis, prognosis, treatment and...
Fri Nov 01, 2019 20:06
Related ArticlesThe dimension of preventable stroke in a large representative patient cohort. Neurology. 2019 Oct 31;: Authors: Boehme C, Toell T, Mayer L, Domig L, Pechlaner R, Willeit K, Tschiderer L, Seekircher L, Willeit P, Griesmacher A, Knoflach M, Willeit J, Kiechl S Abstract OBJECTIVE: To analyze the frequency of inadequately treated risk factors in a large representative cohort of patients with acute ischemic stroke or TIA and to estimate the...
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Related ArticlesDying of amyotrophic lateral sclerosis: Health care use and cost in the last year of life. Neurology. 2019 Oct 31;: Authors: Zwicker J, Qureshi D, Talarico R, Bourque P, Scott M, Chin-Yee N, Tanuseputro P Abstract OBJECTIVE: To describe health care service utilization and cost for decedents with and without amyotrophic lateral sclerosis (ALS) in the last year of life. METHODS: Using linked health administrative data, we conducted...
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Related ArticlesStroke prevention: An uphill battle. Neurology. 2019 Oct 31;: Authors: Beckett LA, Berglund LF PMID: 31672714 [PubMed - as supplied by publisher]
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Related ArticlesCost vs care. Neurology. 2019 Oct 31;: Authors: Russell JA, Dorsey ER PMID: 31672713 [PubMed - as supplied by publisher]
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Related ArticlesCognition at age 70: Life course predictors and associations with brain pathologies. Neurology. 2019 Oct 30;: Authors: Lu K, Nicholas JM, Collins JD, James SN, Parker TD, Lane CA, Keshavan A, Keuss SE, Buchanan SM, Murray-Smith H, Cash DM, Sudre CH, Malone IB, Coath W, Wong A, Henley SMD, Crutch SJ, Fox NC, Richards M, Schott JM Abstract OBJECTIVE: To investigate predictors of performance on a range of cognitive measures including the...
Fri Nov 01, 2019 21:19
Related ArticlesImplementation of quality measures and patient-reported outcomes in an epilepsy clinic. Neurology. 2019 Oct 30;: Authors: Moura LMVR, Magliocco B, Ney JP, Cheng EM, Esper GJ, Hoch DB Abstract OBJECTIVE: To see if systematic collection of patient-reported epilepsy quality measures can identify opportunities to improve care, and to examine the associations between these measures and physical and mental health. METHODS: We developed...
Fri Nov 01, 2019 21:19
Related ArticlesAnaphylactic or tolerant outcomes with IgE. J Allergy Clin Immunol. 2019 Oct 28;: Authors: Kawakami T, Kawakami Y PMID: 31672608 [PubMed - as supplied by publisher]
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Related ArticlesIL-37: A new player in the chronic rhinosinusitis arena. J Allergy Clin Immunol. 2019 Oct 28;: Authors: Markov N, Simon HU PMID: 31672607 [PubMed - as supplied by publisher]
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634 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: health technology These pubmed results were generated on 2019/11/02PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Antibiotics, Vol. 8, Pages 210: Novel Small-molecule Antibacterials against Gram-positive Pathogens of Staphylococcus and Enterococcus Species Antibiotics doi: 10.3390/antibiotics8040210 Authors: Marius Seethaler Tobias Hertlein Björn Wecklein Alba Ymeraj Knut Ohlsen Michael Lalk Andreas Hilgeroth Defeat of the antibiotic resistance of pathogenic bacteria is one great challenge today and for the future. In the last century many classes of effective antibacterials have...
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Antibiotics, Vol. 8, Pages 209: Impact of Periodontal Inflammation on Nutrition and Inflammation Markers in Hemodialysis Patients Antibiotics doi: 10.3390/antibiotics8040209 Authors: Rapone Converti Santacroce Cesarano Vecchiet Cacchio Scacco Grassi Grassi Gnoni Nardi Background: Malnutrition-inflammation complex syndrome (MICS) is a common and usually concurrent condition occurring in patients undergoing hemodialysis (HD), with a pathogenesis...
Fri Nov 01, 2019 02:00
Οι άνδρες που έχουν στο αίμα τους αυξημένα επίπεδα δύο ορμονών, της «ελεύθερης» τεστοστερόνης και του ινσουλινομιμητικού αυξητικού παράγοντα (IGF-I), είναι πιθανότερο να διαγνωσθούν με καρκίνο του προστάτη, σύμφωνα με μία νέα βρετανική επιστημονική έρευνα. Η μελέτη ανοίγει τον δρόμο για την έγκαιρη τροποποίηση του επιπέδου των εν λόγω ορμονών, ώστε να μειωθεί ο κίνδυνος για τη νόσο, η οποία είναι ο δεύτερος συχνότερος καρκίνος μεταξύ των ανδρών παγκοσμίως μετά τον καρκίνο των πνευμόνων (κυρίως λόγω...
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Αυξάνεται ο αριθμός των γυναικών που έχουν διαγνωστεί με αναπλαστικό μεγαλοκυτταρικό λέμφωμα, το οποίο επιστημονικές έρευνες έχουν συνδέσει με εμφυτεύματα που χρησιμοποιούνται στις επεμβάσεις αυξητικής στήθους, ανέφερε ο καθηγητής Αιματολογίας του ΕΚΠΑ, Ευάγγελος Τέρπος, κατά τη διάρκεια συνέντευξης Τύπου. Στην Ελλάδα έχουν διαγνωστεί τρεις γυναίκες με αυτή τη νεοπλασία και μάλιστα μία ασθενής θα ανοίξει τη διεπιστημονική συνεδρία που θα λάβει χώρα στο 30ο Πανελλήνιο Αιματολογικό Συνέδριο (7-10...
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Η σοκολάτα είναι η λαχταριστή αυτή απόλαυση, που αρέσει σε όλους – μικρούς και μεγάλους. Ωστόσο, όπως όλα τα καλά και νόστιμα πράγματα, η κατανάλωση της έχει συνδεθεί με πλήθος αρνητικών για την υγεία επιπτώσεων. Μεταξύ άλλων, θεωρείται ότι η σοκολάτα προκαλεί ακμή, παχυσαρκία, ημικρανία και τερηδόνα. Παράλληλα, η κατανάλωσή της έχει συσχετιστεί και με «μαγικές» αφροδισιακές ιδιότητες. Ποια είναι όμως η πραγματικότητα; Η κατανάλωση σοκολάτας δεν συντελεί στην εμφάνιση ακμής Ξεκινώντας από τη...
Fri Nov 01, 2019 23:10
Είναι γνωστό πως σε περίπτωση που προσβληθείτε από γαστρεντερίτιδα όχι μόνο δεν πρέπει να τρώτε μεγάλες ποσότητες, αλλά πρέπει να είστε επιλεκτικοί σε ότι επιλέξετε να φάτε. Ειδικότερα αυτό που πρέπει να κάνετε το πρώτο 24ωρο της γαστρεντερίτιδας είναι να ενυδατώσετε τον οργανισμό με υγρά. Γι΄αυτό προτιμήστε να φάτε μία σούπα ή να πιείτε ένα τσάι. Μετά από 2 ή 3 ημέρες και αφού νιώσετε καλύτερα, μπορείτε σταδιακά να επανέλθετε στην διατροφική σας ρουτίνα. Μέχρι τότε προτιμήστε τα παρακάτω Τροφές...
Fri Nov 01, 2019 14:56
Microorganisms, Vol. 7, Pages 521: Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients? Microorganisms doi: 10.3390/microorganisms7110521 Authors: Popescu Ursache Feketea Bocsan Jimbu Mesaros Edwards Wang Berceanu Neaga Zdrenghea Despite a plethora of studies demonstrating significant morbidity and mortality due to community-acquired respiratory viral (CRV) infections in intensively treated hematology...
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Microorganisms, Vol. 7, Pages 520: Quality and Safety of Fresh Chicken Fillets after High Pressure Processing: Survival of Indigenous Brochothrix thermosphacta and Inoculated Listeria monocytogenes Microorganisms doi: 10.3390/microorganisms7110520 Authors: Argyri Papadopoulou Sourri Chorianopoulos Tassou The effect of high-pressure processing (HPP) on Listeria monocytogenes, the indigenous microbiota and the shelf-life of chicken fillets was evaluated. Chicken fillets...
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Microorganisms, Vol. 7, Pages 519: Bacterial Consortium for Improved Maize (Zea mays L.) Production Microorganisms doi: 10.3390/microorganisms7110519 Authors: Oluwaseyi Samuel Olanrewaju Olubukola Oluranti Babalola The ever-increasing human population is a major concern for food security. Maize is the third largest most important food crop. The major problems of cultivation arise from urbanization and land pollution. This reduces the amount of land available for agriculture. The use...
Fri Nov 01, 2019 02:00
Publication date: Available online 31 October 2019Source: Molecular and Cellular EndocrinologyAuthor(s): Dianshan Ke, Yu Wang, Yunlong Yu, Yongxuan Wang, Wang Zheng, Xiaomin Fu, Junyong Han, Guoyou Zhang, Jie XuAbstractBackground/purposeIt remains unclear what role curcumin plays in the autophagy of osteoclast precursors (OCPs) during osteoclastogenesis, since some researchers found that curcumin has the ability to inhibit osteoclastogenesis. While others have considered it as an autophagy activator....
Fri Nov 01, 2019 17:47
Publication date: Available online 31 October 2019Source: Molecular and Cellular EndocrinologyAuthor(s): Marthe Rizk-Rabin, Sabrina Chaoui-Ibadioune, Anna Vaczlavik, Christopher Ribes, Michel Polak, Bruno Ragazzon, Jerôme BertheratAbstractAdrenocortical tumors (ACTs) frequently cause steroid excess and present cell-cycle dysregulation. cAMP/PKA signaling is involved in steroid synthesis and play a role in cell-cycle regulation. We investigated, by cell synchronization in the different phases of the...
Fri Nov 01, 2019 17:47
Microorganisms, Vol. 7, Pages 518: Metagenomic Characterization Reveals Pronounced Seasonality in the Diversity and Structure of the Phyllosphere Bacterial Community in a Mediterranean Ecosystem Microorganisms doi: 10.3390/microorganisms7110518 Authors: Despoina Vokou Savvas Genitsaris Katerina Karamanoli Katerina Vareli Marina Zachari Despoina Voggoli Nikolaos Monokrousos John Maxwell Halley Ioannis Sainis We explore how the phyllosphere microbial community responds...
Fri Nov 01, 2019 02:00
Abstract Aim To compare surgical time, bevel angle and site volumetric profiles of osteotomy and resection accomplished by targeted endodontic microsurgery (TEMS) and traditional endodontic microsurgery (EMS) in a surgical simulation model. Methodology An 80x80 mm cone beam computed tomography (CBCT) file was imported into Mimics software where artificial periapical lesions were created encompassing twelve root apices. Maxillary and mandibular models were 3D‐printed. TEMS surgical guides...
Fri Nov 01, 2019 12:33
ABSTRACT Exome sequencing used for molecular diagnosis of Mendelian disorders considerably increases the number of missense variants of unclear significance, whose pathogenicity can be assessed by a variety of prediction tools. As performance of algorithms may vary according to the datasets, complementary specific resources are needed to improve variants interpretation. As a model, we were interested in the Cystic Fibrosis Transmembrane conductance Regulator gene (CFTR) causing cystic fibrosis,...
Fri Nov 01, 2019 12:57
Abstract We have developed a non-invasive diagnostic device for treating thoracic aortic aneurysm that can be applied at a peripheral artery. This study aimed to examine how configuration and size of an aneurysm as well as endoluminal pressure affect our diagnostic device’s ability to detect an aneurysm, using a pulsatile mock circulation. We created three different-sized (12, 16, and 20 mm) saccular and fusiform aneurysm models using silicone and incorporated them in a pulsatile...
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The Incidence of Demodex folliculorum in the Combination of Allergic Rhinitis and Diabetes Mellitus.
Conclusion: DM, AR, advanced age and obesity had prepared the environment for Demodex infestations. This issue should be considered especially in treatment of patients with AR+DM. PMID: 31673265 [PubMed] (Source: Iranian Journal of Parasitology)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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ConclusionSeptoplasty might have an elevated effect on short-term anxiety and postoperative pain. Performing this operation at a late hour in the day might further increase anxiety and pain. However, the latter has no long-term effect on anxiety.ResumoIntroduçãoOs níveis de ansiedade e dor em pacientes submetidos à septoplastia podem variar de acordo com o tempo de cirurgia intradia.ObjetivoInvestigar os efeitos da cirurgia de septoplastia e do tempo de cirurgia intradia na ansiedade e dor pós-operatória.MétodosNoventa...
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ConclusionIt was possible to measure the cortical auditory evoked potential response in the neonatal population using bone vibrator as sound transducer and to draw the profile of the cortical auditory evoked potential latencies and amplitudes by frequencies at the intensity of 60 dBnHL and at the threshold.ResumoIntroduçãoO potencial evocado auditivo cortical traz a possibilidade de avaliar de forma objetiva todo sistema auditivo o que é desejável na população infantil. A estimulação auditiva por...
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CONCLUSIONS: Symptom improvement and revision rates after ESS do not appear to correlate with the degree of concordance between extent of surgery and radiographic disease. More extensive surgery than indicated by CT confers neither greater symptomatic improvement nor long-term detriment. PMID: 31671433 [PubMed - as supplied by publisher] (Source: Rhinology)
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CONCLUSIONS: In patients with CRSwNP, baseline LMK showed extensive sinus opacification and correlated with symptoms, HRQoL, and hyposmia. Dupilumab treatment reduces opacification across all sinuses and related symptoms in patients with CRSwNP. PMID: 31671432 [PubMed - as supplied by publisher] (Source: Rhinology)
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In the original publication of the article, the reference 14 was published incorrectly. The correct reference is given below. (Source: European Archives of Oto-Rhino-Laryngology)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
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This article reviews the fundamentals of neural stimulation and provides an overview of recent major advancements in light-based neuromodulation. ” (Source: Otolaryngologic clinics of North America)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Fri Nov 01, 2019 00:00
This article provides an overview of technique of dentoalveolar distraction osteogenesis to accomplish rapid canine retraction and associated outcomes. When this treatment protocol is implemented well, rapid canine retraction is achieved predictably with minimal side effects. Although current evidence suggests that adverse sequelae, such as root resorptions and pulp devitalization, are rare, prospective clinical studies that are adequately powered and documenting long-term follow-up of these outcomes...
Fri Nov 01, 2019 00:00
As orthodontic treatment has advanced in complexity and in frequency, more recent techniques, using temporary skeletal anchorage, were developed to help correct more severe occlusal and dentofacial discrepancies that were treated with orthognathic surgery alone previously. These techniques have allowed the orthodontist to move teeth against a rigid fixation, allowing for more focused movements of teeth and for orthopedic growth modification. These types of treatments using rigid fixation have allowed...
Fri Nov 01, 2019 00:00
Literature presents controversial maximum phonation time values in children. (Source: Journal of Voice)
Fri Nov 01, 2019 00:00
Otolaryngologists are concerned with form and function of delicate, intricate structures. Until relatively recently, if a nerve could not be sewn back together or grafted, its function could not be restored. This issue of Otolaryngologic Clinics of North America, devoted to Cranial Nerve Stimulation in Otolaryngology and guest edited by Dr Michael Ruckenstein and Dr James Naples, looks at our specialty as it extends past cranial nerve deficits to reach new frontiers of reactivation, of incorporating...
Fri Nov 01, 2019 00:00
This article describes the indications and step-by-step approach of this technique in conjunction with virtual surgical planning. (Source: Oral and Maxillofacial Surgery Clinics)
Fri Nov 01, 2019 00:00
Like sensory maps in other systems, the sense of smell has an organizational structure based on converging projections of olfactory receptor neurons containing unique odorant receptors onto the olfactory bulb in synaptic aggregations termed glomeruli. This organizational structure provides the potential for electrical stimulation and restoration of smell. Prior animal and human studies support the feasibility of an olfactory stimulation device, encouraging ongoing work in development of olfactory...
Fri Nov 01, 2019 00:00
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