IJMS, Vol. 20, Pages 5760: Stem Cells: The Game Changers of Human Cardiac Disease Modelling and Regenerative Medicine International Journal of Molecular Sciences doi: 10.3390/ijms20225760 Authors: Elvira Immacolata Parrotta Stefania Scalise Luana Scaramuzzino Giovanni Cuda A comprehensive understanding of the molecular basis and mechanisms underlying cardiac diseases is mandatory for the development of new and effective therapeutic strategies. The lack of appropriate in vitro...
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IJMS, Vol. 20, Pages 5756: RAF Kinase Inhibitor Protein in Myeloid Leukemogenesis International Journal of Molecular Sciences doi: 10.3390/ijms20225756 Authors: Armin Zebisch Veronica Caraffini Heinz Sill RAF kinase inhibitor protein (RKIP) is an essential regulator of intracellular signaling. A somatic loss of RKIP expression is a frequent event in solid human cancers, and a role of RKIP as metastasis-suppressor is widely accepted nowadays. Recently, RKIP loss has been described...
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IJMS, Vol. 20, Pages 5759: Rapid Regulation of Human Mesenchymal Stem Cell Proliferation Using Inducible Caspase-9 Suicide Gene for Safe Cell-Based Therapy International Journal of Molecular Sciences doi: 10.3390/ijms20225759 Authors: Mari Tsujimura Kosuke Kusamori Makiya Nishikawa The regulation of transplanted cell proliferation and function is important to achieve safe cell-based therapies. We previously reported that the proliferation and function of transplanted cells, which...
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IJMS, Vol. 20, Pages 5758: Long Noncoding RNA (lncRNA)-Mediated Competing Endogenous RNA Networks Provide Novel Potential Biomarkers and Therapeutic Targets for Colorectal Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20225758 Authors: Liye Wang Kwang Bog Cho Yan Li Gabriel Tao Zuoxu Xie Bin Guo Colorectal cancer (CRC) is the third most common cancer and has a high metastasis and reoccurrence rate. Long noncoding RNAs (lncRNAs) play an important role...
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IJMS, Vol. 20, Pages 5757: Flow and Mixing Behavior in a New Bottom Blown Copper Smelting Furnace International Journal of Molecular Sciences doi: 10.3390/ijms20225757 Authors: Pin Shao Lepeng Jiang A mathematical model was developed to describe gas–liquid flow and mixing behavior in a new bottom blown oxygen copper smelting furnace, and the model validation was carried out through a water model experiment. The effects of different nozzle locations, nozzle numbers, and gas...
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IJMS, Vol. 20, Pages 5755: Roles of Transposable Elements in the Different Layers of Gene Expression Regulation International Journal of Molecular Sciences doi: 10.3390/ijms20225755 Authors: Denise Drongitis Francesco Aniello Laura Fucci Aldo Donizetti The biology of transposable elements (TEs) is a fascinating and complex field of investigation. TEs represent a substantial fraction of many eukaryotic genomes and can influence many aspects of DNA function that range from the...
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IJMS, Vol. 20, Pages 5753: Plasma Metabolic Profiling Analysis of Gout Party on Acute Gout Arthritis Rats Based on UHPLC–Q–TOF/MS Combined with Multivariate Statistical Analysis International Journal of Molecular Sciences doi: 10.3390/ijms20225753 Authors: Yuming Wang Chenghao Bi Wentao Pang Yuechen Liu Yu Yuan Huan Zhao Tianpu Zhang Yungang Zhao Yubo Li Gout Party is a Chinese medicine prescription composed of Aconiti Lateralis Radix Praeparaia, Aconiti Radix...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5754: Thyroid Hormone Protects from Fasting-Induced Skeletal Muscle Atrophy by Promoting Metabolic Adaptation International Journal of Molecular Sciences doi: 10.3390/ijms20225754 Authors: Ucci Renzini Russi Mangialardo Cammarata Cavioli Santaguida Virili Centanni Adamo Moresi Verga-Falzacappa Thyroid hormones regulate a wide range of cellular responses, via non-genomic and genomic actions, depending on cell-specific thyroid...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5748: An Overview of Drug Resistance in Protozoal Diseases International Journal of Molecular Sciences doi: 10.3390/ijms20225748 Authors: Capela Moreira Lopes Protozoan diseases continue to be a worldwide social and economic health problem. Increased drug resistance, emerging cross resistance, and lack of new drugs with novel mechanisms of action significantly reduce the effectiveness of current antiprotozoal therapies. While drug resistance associated to...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5750: Associations of microRNAs, Angiogenesis-Regulating Factors and CFH Y402H Polymorphism—An Attempt to Search for Systemic Biomarkers in Age-Related Macular Degeneration International Journal of Molecular Sciences doi: 10.3390/ijms20225750 Authors: Zofia Ulańczyk Anna Sobuś Karolina Łuczkowska Aleksandra Grabowicz Katarzyna Mozolewska-Piotrowska Krzysztof Safranow Miłosz Piotr Kawa Andrzej Pałucha Mariusz Krawczyk Piotr Sikora Ewa Matczyńska...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5752: Opportunities for Antibody Discovery Using Human Pluripotent Stem Cells: Conservation of Oncofetal Targets International Journal of Molecular Sciences doi: 10.3390/ijms20225752 Authors: Heng Liang Tan Andre Choo Pluripotent stem cells (PSCs) comprise both embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). The application of pluripotent stem cells is divided into four main areas, namely: (i) regenerative therapy, (ii) the study and understanding...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5751: Chitosan Ameliorates DSS-Induced Ulcerative Colitis Mice by Enhancing Intestinal Barrier Function and Improving Microflora International Journal of Molecular Sciences doi: 10.3390/ijms20225751 Authors: Jia Wang Cuili Zhang Chunmei Guo Xinli Li Ulcerative colitis (UC) has been identified as one of the inflammatory diseases. Intestinal mucosal barrier function and microflora play major roles in UC. Modified-chitosan products have been consumed as effective...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5746: Polyamine-Induced Hormonal Changes in eds5 and sid2 Mutant Arabidopsis Plants International Journal of Molecular Sciences doi: 10.3390/ijms20225746 Authors: Tajti Hamow Majláth Gierczik Németh Janda Pál Polyamines are multifaceted compounds which play a role in regulating plant growth and stress tolerance in interactions with plant hormones. The aim of the present study was to reveal how exogenous polyamines influence the synthesis...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5749: Genome-Wide Identification and Characterization of FBA Gene Family in Polyploid Crop Brassica napus International Journal of Molecular Sciences doi: 10.3390/ijms20225749 Authors: Zhao Liu Zhang Hu Liu Hua Xu Liu Fructose-1,6-bisphosphate aldolase (FBA) is a versatile metabolic enzyme involved in multiple important processes of glycolysis, gluconeogenesis, and Calvin cycle. Despite its significance in plant biology, the identity...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5747: The Effects of Meldonium on the Renal Acute Ischemia/Reperfusion Injury in Rats International Journal of Molecular Sciences doi: 10.3390/ijms20225747 Authors: Đurašević Stojković Bogdanović Pavlović Borković-Mitić Grigorov Bogojević Jasnić Tosti Đurović Đorđević Todorović Acute renal ischemia/reperfusion (I/R) injury is a clinical condition that is challenging to treat. Meldonium is an anti-ischemic agent that shifts...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5744: Four Cysteine Residues Contribute to Homodimerization of Chicken Interleukin-2 International Journal of Molecular Sciences doi: 10.3390/ijms20225744 Authors: Deng Tan Zhou Wang Lü Xu Zhang Han Ai Interleukin-2 (IL-2) is a pleiotropic cytokine regulating the immune and nervous systems. Mammalian and bird IL-2s have different protein sequences, but perform similar functions. In the current study, two bands were detected by immunoblotting...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5745: Regulation of Inflammatory Response in Human Osteoarthritic Chondrocytes by Novel Herbal Small Molecules International Journal of Molecular Sciences doi: 10.3390/ijms20225745 Authors: Ziadlou Barbero Stoddart Wirth Li Martin Wang Qin Alini Grad In this study, 34 Traditional Chinese Medicine (TCM) compounds were screened for potential anabolic and anti-inflammatory properties on human osteoarthritic (OA) chondrocytes. The...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5743: Meta-iAVP: A Sequence-Based Meta-Predictor for Improving the Prediction of Antiviral Peptides Using Effective Feature Representation International Journal of Molecular Sciences doi: 10.3390/ijms20225743 Authors: Nalini Schaduangrat Chanin Nantasenamat Virapong Prachayasittikul Watshara Shoombuatong In spite of the large-scale production and widespread distribution of vaccines and antiviral drugs, viruses remain a prominent human disease. Recently,...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5741: SiMYB3 in Foxtail Millet (Setaria italica) Confers Tolerance to Low-Nitrogen Stress by Regulating Root Growth in Transgenic Plants International Journal of Molecular Sciences doi: 10.3390/ijms20225741 Authors: Linhao Ge Yining Dou Maomao Li Pengju Qu Zhang He Y Liu Zhaoshi Xu Jun Chen Ming Chen Youzhi Ma Foxtail millet (Setaria italica), which originated in China, has a strong tolerance to low nutrition stresses. However, the mechanism...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5740: Hormone Receptor Expression in Multicentric/Multifocal versus Unifocal Breast Cancer: Especially the VDR Determines the Outcome Related to Focality International Journal of Molecular Sciences doi: 10.3390/ijms20225740 Authors: Alaleh Zati zehni Sven-Niclas Jacob Jan-Niclas Mumm Helene Hildegard Heidegger Nina Ditsch Sven Mahner Udo Jeschke Theresa Vilsmaier The aim of this study was to evaluate the prognostic impact that hormone receptor...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5742: MicroRNA-29a Mitigates Subacromial Bursa Fibrosis in Rotator Cuff Lesion with Shoulder Stiffness International Journal of Molecular Sciences doi: 10.3390/ijms20225742 Authors: Jih-Yang Ko Wei-Shiung Lian Tsai-Chen Tsai Yu-Shan Chen Chin-Kuei Hsieh Chung-Wen Kuo Feng-Sheng Wang Rotator cuff lesion with shoulder stiffness is a major cause of shoulder pain and motionlessness. Subacromial bursa fibrosis is a prominent pathological feature of the...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5739: Design and Synthesis of 4-(Heterocyclic Substituted Amino)-1H-Pyrazole-3-Carboxamide Derivatives and Their Potent Activity against Acute Myeloid Leukemia (AML) International Journal of Molecular Sciences doi: 10.3390/ijms20225739 Authors: Yanle Zhi Zhijie Wang Chao Yao Baoquan Li Hao Heng Jiongheng Cai Li Xiang Yue Wang Tao Lu Shuai Lu Fms-like receptor tyrosine kinase 3 (FLT3) has been emerging as an attractive target for the treatment...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5738: Adiponectin Reverses the Hypothalamic Microglial Inflammation during Short-Term Exposure to Fat-Rich Diet International Journal of Molecular Sciences doi: 10.3390/ijms20225738 Authors: Hannah Lee Thai Hien Tu Byong Seo Park Sunggu Yang Jae Geun Kim Adiponectin, an adipokine derived from the adipose tissue, manifests anti-inflammatory effects in the metabolically active organs and is, therefore, beneficial in various metabolic diseases associated...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5736: In Situ Analysis of DNA-Protein Complex Formation upon Radiation-Induced DNA Damage International Journal of Molecular Sciences doi: 10.3390/ijms20225736 Authors: Giulio Ticli Ennio Prosperi The importance of determining at the cellular level the formation of DNA–protein complexes after radiation-induced lesions to DNA is outlined by the evidence that such interactions represent one of the first steps of the cellular response to DNA damage. These...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5733: Neuronal Death in the Contralateral Un-Injured Retina after Unilateral Axotomy: Role of Microglial Cells International Journal of Molecular Sciences doi: 10.3390/ijms20225733 Authors: Fernando Lucas-Ruiz Caridad Galindo-Romero Kristy T. Rodríguez-Ramírez Manuel Vidal-Sanz Marta Agudo-Barriuso For years it has been known that unilateral optic nerve lesions induce a bilateral response that causes an inflammatory and microglial response in the contralateral...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5737: Adaptive Laboratory Evolution of Cupriavidus necator H16 for Carbon Co-Utilization with Glycerol International Journal of Molecular Sciences doi: 10.3390/ijms20225737 Authors: Miriam González-Villanueva Hemanshi Galaiya Paul Staniland Jessica Staniland Ian Savill Tuck Seng Wong Kang Lan Tee Cupriavidus necator H16 is a non-pathogenic Gram-negative betaproteobacterium that can utilize a broad range of renewable heterotrophic resources to produce...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5734: A Single Synonymous Variant (c.354G>A [p.P118P]) in ADAMTS13 Confers Enhanced Specific Activity International Journal of Molecular Sciences doi: 10.3390/ijms20225734 Authors: Ryan Hunt Gaya Hettiarachchi Upendra Katneni Nancy Hernandez David Holcomb Jacob Kames Redab Alnifaidy Brian Lin Nobuko Hamasaki-Katagiri Aaron Wesley Tal Kafri Christina Morris Laura Bouché Maria Panico Tal Schiller Juan Ibla Haim Bar Amra...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5732: Mutation-Driven Signals of ARID1A and PI3K Pathways in Ovarian Carcinomas: Alteration Is An Opportunity International Journal of Molecular Sciences doi: 10.3390/ijms20225732 Authors: Pradip De Nandini Dey The chromosome is a functionally dynamic structure. The dynamic nature of chromosome functionally connects it to almost every event within a cell, in health and sickness. Chromatin remodeling system acts in unison with the cell survival pathway in mediating...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5735: Hepatic microRNA Expression by PGC-1α and PGC-1β in the Mouse International Journal of Molecular Sciences doi: 10.3390/ijms20225735 Authors: Elena Piccinin Maria Arconzo Giusi Graziano Michele Vacca Claudia Peres Elena Bellafante Gaetano Villani Antonio Moschetta The fine-tuning of liver metabolism is essential to maintain the whole-body homeostasis and to prevent the onset of diseases. The peroxisome proliferator-activated receptor-γ...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5731: Melanoma and Vitiligo: In Good Company International Journal of Molecular Sciences doi: 10.3390/ijms20225731 Authors: Cristina Maria Failla Maria Luigia Carbone Cristina Fortes Gianluca Pagnanelli Stefania D’Atri Cutaneous melanoma represents the most aggressive form of skin cancer, whereas vitiligo is an autoimmune disorder that leads to progressive destruction of skin melanocytes. However, vitiligo has been associated with cutaneous melanoma since...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5729: An Association of Serotonin with Pain Disorders and Its Modulation by Estrogens International Journal of Molecular Sciences doi: 10.3390/ijms20225729 Authors: Stephania Paredes Santiago Cantillo Kenneth D. Candido Nebojsa Nick Knezevic Ovarian hormones play an important role in pain perception, and are responsible, at least in part, for the pain threshold differences between the sexes. Modulation of pain and its perception are mediated by neurochemical...
Fri Nov 15, 2019 02:00
IJMS, Vol. 20, Pages 5730: Short-Term Microgravity Influences Cell Adhesion in Human Breast Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms20225730 Authors: Mohamed Zakaria Nassef Sascha Kopp Daniela Melnik Thomas J. Corydon Jayashree Sahana Marcus Krüger Markus Wehland Thomas J. Bauer Christian Liemersdorf Ruth Hemmersbach Manfred Infanger Daniela Grimm With the commercialization of spaceflight and the exploration of space,...
Fri Nov 15, 2019 02:00
JCM, Vol. 8, Pages 2001: Should We Offer In Vitro Fertilization to Couples with Unexplained Recurrent Pregnancy Loss? Journal of Clinical Medicine doi: 10.3390/jcm8112001 Authors: Michal Kirshenbaum Raoul Orvieto In clinical practice, empirical treatments are often offered to couples with recurrent pregnancy loss, including in vitro fertilization. Given that most patients with recurrent pregnancy loss are fertile, the scientific rationale of in vitro fertilization for these couple...
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JCM, Vol. 8, Pages 2002: Potential Utility of Neurosonology in Paroxysmal Atrial Fibrillation Detection in Patients with Cryptogenic Stroke Journal of Clinical Medicine doi: 10.3390/jcm8112002 Authors: Chrissoula Liantinioti Lina Palaiodimou Konstantinos Tympas John Parissis Aikaterini Theodorou Ignatios Ikonomidis Maria Chondrogianni Christina Zompola Sokratis Triantafyllou Andromachi Roussopoulou Odysseas Kargiotis Aspasia Serdari Anastasios Bonakis Konstantinos...
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JCM, Vol. 8, Pages 2000: Management of High-Pressure Injection Hand Injuries: A Multicentric, Retrospective, Observational Study Journal of Clinical Medicine doi: 10.3390/jcm8112000 Authors: Ermanno Vitale Caterina Ledda Roberto Adani Mario Lando Massimo Bracci Emanuele Cannizzaro Luigi Tarallo Venerando Rapisarda Hand injuries after high-pressure injection are a medical emergency. These events occur frequently in workers during industrial cleaning, painting, and...
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JCM, Vol. 8, Pages 1998: Physical Health and Psychological Outcomes in Adult Patients with Long-bone Fracture Non-unions: Evidence Today Journal of Clinical Medicine doi: 10.3390/jcm8111998 Authors: Johnson Igoe Kleftouris Papachristos Papakostidis Giannoudis Background: Research has suggested that bone fractures can hinder the health status of patients’ life. However, limited research has examined the impact that the healing process of a fracture has on...
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JCM, Vol. 8, Pages 1997: Choice of Donor Source and Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Sickle Cell Disease Journal of Clinical Medicine doi: 10.3390/jcm8111997 Authors: Emily Limerick Courtney Fitzhugh In the United States, one out of every 500 African American children have sickle cell disease (SCD), and SCD affects approximately 100,000 Americans. Significant advances in the treatment of this monogenetic disorder have failed to substantially extend...
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JCM, Vol. 8, Pages 1996: Kambin’s Triangle Approach versus Traditional Safe Triangle Approach for Percutaneous Transforaminal Epidural Adhesiolysis Using an Inflatable Balloon Catheter: A Pilot Study Journal of Clinical Medicine doi: 10.3390/jcm8111996 Authors: Gil Jeong Cho Choi Nahm Lee Spinal stenosis is a common condition in elderly individuals. Many patients are unresponsive to the conventional treatment. If the transforaminal epidural block does not exert a...
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JCM, Vol. 8, Pages 1999: Effects of Volatile versus Total Intravenous Anesthesia on Occurrence of Myocardial Injury after Non-Cardiac Surgery Journal of Clinical Medicine doi: 10.3390/jcm8111999 Authors: Kwon Park Lee Oh Lee Min The cardioprotective effects of volatile anesthetics versus total intravenous anesthesia (TIVA) are controversial, especially in patients undergoing non-cardiac surgery. Using current generation high-sensitivity cardiac troponin (hs-cTn),...
Fri Nov 15, 2019 02:00
JCM, Vol. 8, Pages 1994: Preeclampsia with Intrauterine Growth Restriction Generates Morphological Changes in Endothelial Cells Associated with Mitochondrial Swelling—An In Vitro Study Journal of Clinical Medicine doi: 10.3390/jcm8111994 Authors: Dorota Formanowicz Agnieszka Malińska Marcin Nowicki Katarzyna Kowalska Karolina Gruca-Stryjak Grzegorz Bręborowicz Katarzyna Korybalska Pregnancy complicated by preeclampsia (PE) and intrauterine growth restriction (IUGR)...
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JCM, Vol. 8, Pages 1995: Enrichment of Exosome-Like Extracellular Vesicles from Plasma Suitable for Clinical Vesicular miRNA Biomarker Research Journal of Clinical Medicine doi: 10.3390/jcm8111995 Authors: Moon Shin Kim Lee Mankhong Yang Lee Park Kwak Lee Kang Exosome-like extracellular vesicles (ELVs) contain biomolecules that have potential as diagnostic biomarkers, such as proteins, micro-RNAs (miRNAs), and lipids. However, it is difficult...
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JCM, Vol. 8, Pages 1992: Cell Blood Count Alterations and Patterns of Anaemia in Autoimmune Atrophic Gastritis at Diagnosis: A Multicentre Study Journal of Clinical Medicine doi: 10.3390/jcm8111992 Authors: Marco Vincenzo Lenti Edith Lahner Gaetano Bergamaschi Emanuela Miceli Laura Conti Sara Massironi Sara Cococcia Alessandra Zilli Flavio Caprioli Maurizio Vecchi Stefania Maiero Renato Cannizzaro Gino Roberto Corazza Bruno Annibale Antonio Di Sabatino...
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JCM, Vol. 8, Pages 1993: Interleukin-18 Is a Prognostic Biomarker Correlated with CD8+ T Cell and Natural Killer Cell Infiltration in Skin Cutaneous Melanoma Journal of Clinical Medicine doi: 10.3390/jcm8111993 Authors: Minchan Gil Kyung Eun Kim Interleukin-18 (IL-18) is a cytokine that enhances innate and adaptive immune responses. Although there are conflicting reports about the roles of IL-18 in melanoma progression, the clinical relevance of IL-18 expression has not been comprehensively...
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JCM, Vol. 8, Pages 1991: Association between Albumin–Globulin Ratio and Mortality in Patients with Chronic Kidney Disease Journal of Clinical Medicine doi: 10.3390/jcm8111991 Authors: Pin-Pin Wu Yao-Peng Hsieh Chew-Teng Kor Ping-Fang Chiu Background: Malnutrition and inflammation are highly prevalent and tightly regulated with each other in chronic kidney disease (CKD) patients. Inflammation can lead to malnutrition in patients with sufficient nourishment, while malnutrition...
Fri Nov 15, 2019 02:00
JCM, Vol. 8, Pages 1989: Targeting of the Cancer-Associated Fibroblast—T-Cell Axis in Solid Malignancies Journal of Clinical Medicine doi: 10.3390/jcm8111989 Authors: Tom J. Harryvan Els M. E. Verdegaal James C. H. Hardwick Lukas J. A. C. Hawinkels Sjoerd H. van der Burg The introduction of a wide range of immunotherapies in clinical practice has revolutionized the treatment of cancer in the last decade. The majority of these therapeutic modalities are centered on reinvigorating...
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JCM, Vol. 8, Pages 1988: Elevated Serum 25-Hydroxyvitamin D Levels Are Associated with Improved Bone Formation and Micro-Structural Measures in Elderly Hip Fracture Patients Journal of Clinical Medicine doi: 10.3390/jcm8111988 Authors: Deepti Sharma Rebecca Sawyer Thomas Robertson Roumen Stamenkov Lucian Solomon Gerald Atkins Peter Clifton Howard Morris Paul Anderson Vitamin D, along with calcium, is generally considered necessary for bone health and reduction...
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JCM, Vol. 8, Pages 1990: Rivaroxaban Effects Illustrate the Underestimated Importance of Activated Platelets in Thrombin Generation Assessed by Calibrated Automated Thrombography Journal of Clinical Medicine doi: 10.3390/jcm8111990 Authors: Stephanie Makhoul Marina Panova-Noeva Véronique Regnault Wolfram Ruf Philip Wenzel Jeremy Lagrange Background: The direct oral anticoagulant rivaroxaban inhibiting specifically activated factor X (FXa) causes delayed thrombin generation...
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JCM, Vol. 8, Pages 1986: microRNAs Are Key Regulators in Chronic Lung Disease: Exploring the Vital Link between Disease Progression and Lung Cancer Journal of Clinical Medicine doi: 10.3390/jcm8111986 Authors: Mathew Suji Eapen Kielan Darcy McAlinden Stephen Myers Wenying Lu Sukhwinder Singh Sohal microRNAs (miRNAs) bind to mRNAs and inhibit their expression through post-transcriptionally regulating gene expression. Here, we elaborate upon the concise summary of the role...
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JCM, Vol. 8, Pages 1985: The Value of Adding Surveillance Cultures to Fluoroquinolone Prophylaxis in the Management of Multiresistant Gram Negative Bacterial Infections in Acute Myeloid Leukemia Journal of Clinical Medicine doi: 10.3390/jcm8111985 Authors: Christelle Castañón Ahinoa Fernández Moreno Ana María Fernández Verdugo Javier Fernández Carmen Martínez Ortega Miguel Alaguero Concepción Nicolás Laura Vilorio Marqués Teresa Bernal Multidrug resistant Gram-Negative...
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JCM, Vol. 8, Pages 1987: Risk Factors and Outcomes of Preterm Premature Rupture of Membranes in a Cohort of 6968 Pregnant Women Prospectively Recruited Journal of Clinical Medicine doi: 10.3390/jcm8111987 Authors: Damien Bouvier Jean-Claude Forest Loïc Blanchon Emmanuel Bujold Bruno Pereira Nathalie Bernard Denis Gallot Vincent Sapin Yves Giguère We revisited risk factors and outcomes related to the preterm premature rupture of membranes (PPROM). A total of 7866...
Fri Nov 15, 2019 02:00
JCM, Vol. 8, Pages 1984: Low Pre-Treatment Count of Circulating Endothelial Progenitors as a Prognostic Biomarker of the High Risk of Breast Cancer Recurrence Journal of Clinical Medicine doi: 10.3390/jcm8111984 Authors: Piotr Rhone Kornel Bielawski Katarzyna Ziołkowska Danuta Rość Barbara Ruszkowska-Ciastek Neoangiogenesis is mediated by circulating bone marrow-derived endothelial progenitors (circulating EPCs). The aim of the study was the quantification of circulating...
Fri Nov 15, 2019 02:00
J. Imaging, Vol. 5, Pages 85: Endmember Learning with K-Means through SCD Model in Hyperspectral Scene Reconstructions Journal of Imaging doi: 10.3390/jimaging5110085 Authors: Ayan Chatterjee Peter W. T. Yuen This paper proposes a simple yet effective method for improving the efficiency of sparse coding dictionary learning (DL) with an implication of enhancing the ultimate usefulness of compressive sensing (CS) technology for practical applications, such as in hyperspectral imaging...
Fri Nov 15, 2019 02:00
JPM, Vol. 9, Pages 49: A Perspective on Microneedle-Based Drug Delivery and Diagnostics in Paediatrics Journal of Personalized Medicine doi: 10.3390/jpm9040049 Authors: Liliana R Pires KB Vinayakumar Maria Turos Verónica Miguel João Gaspar Microneedles (MNs) have been extensively explored in the literature as a means to deliver drugs in the skin, surpassing the stratum corneum permeability barrier. MNs are potentially easy to produce and may allow the self-administration...
Fri Nov 15, 2019 02:00
JPM, Vol. 9, Pages 48: Role of Receptor Profiling for Personalized Therapy in a Patient with a Growth Hormone-Secreting Macroadenoma Resistant to First-Generation Somatostatin Analogues Journal of Personalized Medicine doi: 10.3390/jpm9040048 Authors: Krystallenia I. Alexandraki Eirini Papadimitriou Vasiliki Mavroeidi Georgios Kyriakopoulos Antonios Xydakis Theodoros G. Papaioannou Denise Kolomodi Gregory A. Kaltsas Ashley B. Grossman Background: Acromegaly is...
Fri Nov 15, 2019 02:00
Medicina, Vol. 55, Pages 745: Towards a Transversal Definition of Psychological Resilience: A Literature Review Medicina doi: 10.3390/medicina55110745 Authors: Antonella Sisto Flavia Vicinanza Laura Leondina Campanozzi Giovanna Ricci Daniela Tartaglini Vittoradolfo Tambone Background and objectives: This paper addresses psychological resilience, a multidisciplinary theoretical construct with important practical implications for health sciences. Although many definitions...
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Medicina, Vol. 55, Pages 743: Retrospective Evaluation of Lung Adenocarcinoma Patients Progressing on 1st Line Chemotherapy Medicina doi: 10.3390/medicina55110743 Authors: Heikki Vilhonen Samu Kurki Tarja Laitinen Samuli Hirsjärvi Background and Objectives: Evaluation of data from electronic health care records could help in guiding towards more rational drug treatments. This single center study evaluated clinical characteristics that could be associated with disease progression....
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Medicina, Vol. 55, Pages 742: The Effect of Mean Platelet Volume/Platelet Count Ratio on Dipper and Non-Dipper Blood Pressure Status Medicina doi: 10.3390/medicina55110742 Authors: Murat Meric Serkan Yuksel Metin Coksevim Okan Gulel Background and Objectives: The mean platelet volume (MPV) represents a possible marker of platelet activation. There is an association between the platelet count (PC) and inflammation and platelet reactivity. We assessed the association between the...
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Medicina, Vol. 55, Pages 744: The Trends of Complicated Acute Colonic Diverticulitis—A Systematic Review of the National Administrative Databases Medicina doi: 10.3390/medicina55110744 Authors: Roberto Cirocchi Georgi Popivanov Alessia Corsi Antonio Amato Riccardo Nascimbeni Rosario Cuomo Bruno Annibale Marina Konaktchieva Gian Andrea Binda Background and Objectives: The diverticular disease includes a broad spectrum of different “clinical situations”...
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Medicina, Vol. 55, Pages 741: Affective and Substance Abuse Disorders Following Abortion by Pregnancy Intention in the United States: A Longitudinal Cohort Study Medicina doi: 10.3390/medicina55110741 Authors: Sullins Background and Objectives: Psychological outcomes following termination of wanted pregnancies have not previously been studied. Does excluding such abortions affect estimates of psychological distress following abortion? To address this question this study examines long-term...
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Medicina, Vol. 55, Pages 740: Influence of Functional Classification on Skill Tests in Elite Female Wheelchair Basketball Athletes Medicina doi: 10.3390/medicina55110740 Authors: Kaori Tachibana Hirotaka Mutsuzaki Yukiyo Shimizu Takashi Doi Kazushi Hotta Yasuyoshi Wadano Background and objectives: Wheelchair basketball players are classified into four functional classes according to the player’s “volume of action”, characterized by trunk movement...
Fri Nov 15, 2019 02:00
Medicines, Vol. 6, Pages 112: Itch in Chronic Wounds: Pathophysiology, Impact, and Management Medicines doi: 10.3390/medicines6040112 Authors: Michela Iannone Agata Janowska Valentina Dini Giulia Tonini Teresa Oranges Marco Romanelli Background: The aims of this review are to analyze the current literature regarding the characteristics and pathophysiological mechanisms of itch in chronic wounds, to assess the impact on quality of life and delayed-healing, to focus on the...
Fri Nov 15, 2019 02:00
Medicines, Vol. 6, Pages 111: Sweet’s Syndrome Following Therapy with Hydroxychloroquine in a Patient Affected with Elderly-Onset Primary Sjogren’s Syndrome Medicines doi: 10.3390/medicines6040111 Authors: Ciro Manzo Nazareno Pollio Maria Natale Sweet’s syndrome is an uncommon skin disease characterized by painful polymorphic lesions associated with fever and neutrophilia. When biopsied, these lesions reveal a diffuse infiltrate of mature neutrophils in the papillary...
Fri Nov 15, 2019 02:00
Membranes, Vol. 9, Pages 154: Preventing Silica Scale Formation Using Hydroxide Ions Generated by Water Electrolysis Membranes doi: 10.3390/membranes9110154 Authors: Sano Yamaguchi The reaction of silica with various cations in a solution and with hydroxide ions generated by water electrolysis was investigated as a means of preventing the formation of silica scales in geothermal binary power generation. Through batch and continuous experiments, it was found that all silica in the...
Fri Nov 15, 2019 02:00
MPs, Vol. 2, Pages 86: A Method to Reuse Archived H&E Stained Histology Slides for a Multiplex Protein Biomarker Analysis Methods and Protocols doi: 10.3390/mps2040086 Authors: James P. Hinton Katerina Dvorak Esteban Roberts Wendy J. French Jon C. Grubbs Anne E. Cress Hina A. Tiwari Raymond B. Nagle Archived Hematoxylin and Eosin (H&E) stained pathology slides are routinely stored to index formalin-fixed paraffin-embedded (FFPE) sample tissue blocks....
Fri Nov 15, 2019 02:00
Microorganisms, Vol. 7, Pages 567: Transcriptome Analysis of Choke Stroma and Asymptomatic Inflorescence Tissues Reveals Changes in Gene Expression in Both Epichloë festucae and Its Host Plant Festuca rubra subsp. rubraMicroorganisms doi: 10.3390/microorganisms7110567Authors: Wang Clarke BelangerMany cool-season grasses have symbiotic relationships with Epichloë (Ascomycota, Clavicipitaceae) fungal endophytes that inhabit the intercellular spaces of the above-ground parts of the host plants....
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Microorganisms, Vol. 7, Pages 566: Identification of A Novel Arsenic Resistance Transposon Nested in A Mercury Resistance Transposon of Bacillus sp. MB24Microorganisms doi: 10.3390/microorganisms7110566Authors:Mei-Fang ChienYing-Ning HoHui-Erh YangMasaru NaritaKeisuke MiyauchiGinro EndoChieh-Chen HuangA novel TnMERI1-like transposon designated as TnMARS1 was identified from mercury resistant Bacilli isolated from Minamata Bay sediment. Two adjacent ars operon-like gene clusters, ars1 and ars2, flanked...
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Microorganisms, Vol. 7, Pages 568: Multiple Lineages of Usutu Virus (Flaviviridae, Flavivirus) in Blackbirds (Turdus merula) and Mosquitoes (Culex pipiens, Cx. modestus) in the Czech Republic (2016–2019)Microorganisms doi: 10.3390/microorganisms7110568Authors:Vaclav HönigMartin PalusTomas KasparMarta ZemanovaKarolina MajerovaLada HofmannovaPetr PapezikSilvie SikutovaFrantisek RettichZdenek HubalekIvo RudolfJan VotypkaDavid ModryDaniel RuzekUsutu virus (USUV) is a flavivirus (Flaviviridae: Flavivirus)...
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Molecules, Vol. 24, Pages 4160: In Silico Molecular Studies of Antiophidic Properties of the Amazonian Tree Cordia nodosa Lam. Molecules doi: 10.3390/molecules24224160 Authors: Luzuriaga-Quichimbo Blanco-Salas Muñoz-Centeno Peláez Cerón-Martínez Ruiz-Téllez We carried out surveys on the use of Cordia nodosa Lam. in the jungles of Bobonaza (Ecuador). We documented this knowledge to prevent its loss under the Framework of the Convention on Biological Diversity and...
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Molecules, Vol. 24, Pages 4159: A Molecular Electron Density Theory Study of the Synthesis of Spirobipyrazolines through the Domino Reaction of Nitrilimines with Allenoates Molecules doi: 10.3390/molecules24224159 Authors: Luis R. Domingo Fatemeh Ghodsi Mar Ríos-Gutiérrez The reaction of diphenyl nitrilimine (NI) with methyl 1-methyl-allenoate yielding a spirobipyrazoline has been studied within molecular electron density theory (MEDT) at the MPWB1K/6-311G(d) computational level...
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Molecules, Vol. 24, Pages 4161: Pyrido[2,3-d]pyrimidin-7(8H)-ones: Synthesis and Biomedical Applications Molecules doi: 10.3390/molecules24224161 Authors: Guillem Jubete Raimon Puig de la Bellacasa Roger Estrada-Tejedor Jordi Teixidó José I. Borrell Pyrido[2,3-d]pyrimidines (1) are a type of privileged heterocyclic scaffolds capable of providing ligands for several receptors in the body. Among such structures, our group and others have been particularly interested in pyrido[2,3-d]pyrimidine-7(8H)-ones...
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Molecules, Vol. 24, Pages 4158: Essential Oil from Arnica Montana L. Achenes: Chemical Characteristics and Anticancer Activity Molecules doi: 10.3390/molecules24224158 Authors: Sugier Sugier Jakubowicz-Gil Winiarczyk Kowalski Mountain arnica Arnica montana L. is a source of several metabolite classes with diverse biological activities. The chemical composition of essential oil and its major volatile components in arnica may vary depending on the geographical region,...
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Molecules, Vol. 24, Pages 4156: Passivating Surface States on Water Splitting Cuprous Oxide Photocatalyst with Bismuth Decoration Molecules doi: 10.3390/molecules24224156 Authors: Yuhong Huang Hongkuan Yuan Hong Chen To enhance the visible light photocatalystic activity of Cu 2 O(100) surface, we performed first-principles calculations on the structural, electronic and optical properties of a bismuth (Bi)-decorated Cu 2 O(100) surface (Bi@Cu 2 O(100)). It is...
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Molecules, Vol. 24, Pages 4157: Effect of Ultrasound on the Green Selective Oxidation of Benzyl Alcohol to Benzaldehyde Molecules doi: 10.3390/molecules24224157 Authors: Marion L. Chevallier Sarah Dessolin Fanny Serres Lucile Bruyas Gregory Chatel Oxidation of alcohols plays an important role in industrial chemistry. Novel green techniques, such as sonochemistry, could be economically interesting by improving industrial synthesis yield. In this paper, we studied the selective...
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Molecules, Vol. 24, Pages 4154: Copper-Mediated Nitrosation: 2-Nitrosophenolato Complexes and Their Use in the Synthesis of Heterocycles Molecules doi: 10.3390/molecules24224154 Authors: Alexander J. Nicholls Andrei S. Batsanov Ian R. Baxendale A simple protocol yielding ortho-substituted nitrosophenols from phenols is demonstrated, in the form of copper(II) bis(nitrosophenolato) complexes. The developed methodology was applied to a range of substrates, confirming the role of the...
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Molecules, Vol. 24, Pages 4155: Synthesis of Novel Farnesoid X Receptor Agonists and Validation of Their Efficacy in Activating Differentiation of Mouse Bone Marrow-Derived Mesenchymal Stem Cells into Osteoblasts Molecules doi: 10.3390/molecules24224155 Authors: Ko Fujimori Yusuke Iguchi Yukiko Yamashita Keigo Gohda Naoki Teno The modulators of farnesoid X receptor (FXR), a bile acid receptor, regulate various biological processes including bile acid metabolism, and are associated...
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Molecules, Vol. 24, Pages 4153: Regulation of MicroRNA-155 and Its Related Genes Expression by Inositol Hexaphosphate in Colon Cancer Cells Molecules doi: 10.3390/molecules24224153 Authors: Małgorzata Kapral Joanna Wawszczyk Ludmiła Węglarz Inositol hexaphosphate (IP6), a natural dietary component, has been found as an antitumor agent by stimulating apoptosis and inhibiting cancer cell proliferation, their migration, and metastasis in diverse cancers including colon cancer. However,...
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Molecules, Vol. 24, Pages 4152: Novel Carbon Dots Derived from Puerariae lobatae Radix and Their Anti-Gout Effects Molecules doi: 10.3390/molecules24224152 Authors: Xiaoke Wang Yue Zhang Meiling Zhang Hui Kong Suna Wang Jinjun Cheng Huihua Qu Yan Zhao Gout is a disease with a high incidence and causing great harm, and the current treatment drugs are not satisfactory. In this study, novel water-soluble carbon dots (CDs) with anti-gout effect, named Puerariae lobatae...
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Molecules, Vol. 24, Pages 4151: Synthesis and Antimicrobial Activity of Methoxy- Substituted γ-Oxa-ε-lactones Derived from Flavanones Molecules doi: 10.3390/molecules24224151 Authors: Witold Gładkowski Monika Siepka Tomasz Janeczko Edyta Kostrzewa-Susłow Jarosław Popłoński Marcelina Mazur Barbara Żarowska Wojciech Łaba Gabriela Maciejewska Czesław Wawrzeńczyk Six γ-oxa-ε-lactones, 4-phenyl-3,4-dihydro-2H-1,5-benzodioxepin-2-one (5a) and...
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Molecules, Vol. 24, Pages 4149: Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine- Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tomography Molecules doi: 10.3390/molecules24224149 Authors: Ritawidya Wenzel Teodoro Toussaint Kranz Deuther-Conrad Dukic-Stefanovic Ludwig Scheunemann Brust A specific radioligand for the imaging of cyclic nucleotide phosphodiesterase 2A (PDE2A)...
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Molecules, Vol. 24, Pages 4148: Membrane Processes for Microplastic Removal Molecules doi: 10.3390/molecules24224148 Authors: Poerio Piacentini Mazzei Plastic pollution of the aquatic environment is a major concern considering the disastrous impact on the environment and on human beings. The significant and continuous increase in the production of plastics causes an enormous amount of plastic waste on the land entering the aquatic environment. Furthermore, wastewater treatment...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4150: Immunomodulatory Effects of Phosphorylated Radix Cyathulae officinalis Polysaccharides in Immunosuppressed Mice Molecules doi: 10.3390/molecules24224150 Authors: Feng Fan Lin Liu Chai Yang This research aimed to investigate the immunomodulatory effects of phosphorylated Radix Cyathulae officinalis Kuan polysaccharides (pRCPS) in immunosuppressed mice, improving their cellular and humoral immune function. Our results showed that pRCPS...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4146: “Fishing and Hunting”—Selective Immobilization of a Recombinant Phenylalanine Ammonia-Lyase from Fermentation Media Molecules doi: 10.3390/molecules24224146 Authors: Sánta-Bell Molnár Varga Nagy Hornyánszky Paizs Balogh-Weiser Poppe This article overviews the numerous immobilization methods available for various biocatalysts such as whole-cells, cell fragments, lysates or enzymes which do not require preliminary enzyme purification...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4147: Some Biogenetic Considerations Regarding the Marine Natural Product (−)-Mucosin Molecules doi: 10.3390/molecules24224147 Authors: Jens M. J. Nolsøe Marius Aursnes Yngve H. Stenstrøm Trond V. Hansen Recently, the identity of the marine hydrindane natural product (−)-mucosin was revised to the trans-fused structure 6, thereby providing a biogenetic puzzle that remains to be solved. We are now disseminating some of our insights with regard...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4144: Insight into the Structure and Properties of Novel Imidazole-Based Salts of Salicylic Acid Molecules doi: 10.3390/molecules24224144 Authors: Inês C. B. Martins Dominik Al-Sabbagh Klas Meyer Michael Maiwald Gudrun Scholz Franziska Emmerling The preparation of new active pharmaceutical ingredient (API) multicomponent crystal forms, especially co-crystals and salts, is being considered as a reliable strategy to improve API solubility and bioavailability....
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4143: Dialkylation of Indoles with Trichloroacetimidates to Access 3,3-Disubstituted Indolenines Molecules doi: 10.3390/molecules24224143 Authors: Tamie Suzuki Nilamber A. Mate Arijit A. Adhikari John D. Chisholm 2-Substituted indoles may be directly transformed to 3,3-dialkyl indolenines with trichloroacetimidate electrophiles and the Lewis acid TMSOTf. These reactions provide rapid access to complex indolenines which are present in a variety of complex...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4145: Warfarin-Capped Gold Nanoparticles: Synthesis, Cytotoxicity, and Cellular Uptake Molecules doi: 10.3390/molecules24224145 Authors: Loredana Florina Leopold Dumitriţa Rugină Ioana Oprea Zorița Diaconeasa Nicolae Leopold Maria Suciu Vasile Coman Dan Cristian Vodnar Adela Pintea Cristina Coman Currently, research studies on nanoparticle cytotoxicity, uptake or internalization into the body’s cells are of great interest...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4141: Application of N-Dodecyl l-Peptide to Enhance Serum Stability while Maintaining Inhibitory Effects on Myometrial Contractions Ex Vivo Molecules doi: 10.3390/molecules24224141 Authors: Julien Poupart Xin Hou Sylvain Chemtob William D. Lubell N-Alkylation and N-acylation of the prostaglandin-F2α allosteric modulator l-PDC31 were performed to install various alkyl, PEG and isoprenoid groups onto the l-enantiomer of the peptide. Among the...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4140: Lunasin Improves the LDL-C Lowering Efficacy of Simvastatin via Inhibiting PCSK9 Expression in Hepatocytes and ApoE−/− Mice Molecules doi: 10.3390/molecules24224140 Authors: Lili Gu Yaqin Gong Cheng Zhao Yue Wang Qinghua Tian Gaoxin Lei Yalin Liang Wenfeng Zhao Shuhua Tan Statins are the most popular therapeutic drugs to lower plasma low density lipoprotein cholesterol (LDL-C) synthesis by competitively inhibiting hydroxyl-3-methyl-glutaryl-CoA...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4142: Fabricating Fibers of a Porous-Polystyrene Shell and Particle-Loaded Core Molecules doi: 10.3390/molecules24224142 Authors: Dharneedar Ravichandran Weiheng Xu Rahul Franklin Namrata Kanth Sayli Jambhulkar Sumedh Shukla Kenan Song Polystyrene (PS) polymers have broad applications in protective packaging for food shipping, containers, lids, bottles, trays, tumblers, disposable cutlery and the making of models. Currently, most PS products,...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4139: In Vitro Evaluation of Chemically Analyzed Hypericum Triquetrifolium Extract Efficacy in Apoptosis Induction and Cell Cycle Arrest of the HCT-116 Colon Cancer Cell Line Molecules doi: 10.3390/molecules24224139 Authors: Shahinaz Mahajna Sleman Kadan Zipora Tietel Bashar Saad Said Khasib Aziz Tumeh Doron Ginsberg Hilal Zaid Naturally derived drugs and plant-based products are attractive commodities that are being explored for cancer...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4137: Facile Synthesis of Novel Prussian Blue–Lipid Nanocomplexes Molecules doi: 10.3390/molecules24224137 Authors: Maria Antònia Busquets Ariadna Novella-Xicoy Valeria Guzmán Joan Estelrich Prussian blue (PB) is known for its multiple applications ranging from fine arts to therapeutics. More recently, PB nanoparticles have been pointed to as appealing photothermal agents (PA) when irradiated with wavelengths corresponding to the biological windows,...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4138: Potent Cytotoxicity of Novel L-Shaped Ortho-Quinone Analogs through Inducing Apoptosis Molecules doi: 10.3390/molecules24224138 Authors: Sheng-You Li Ze-Kun Sun Xue-Yi Zeng Yue Zhang Meng-Ling Wang Sheng-Cao Hu Jun-Rong Song Jun Luo Chao Chen Heng Luo Wei-Dong Pan Twenty-seven L-shaped ortho-quinone analogs were designed and synthesized using a one pot double-radical synthetic strategy followed by removing methyl at C-3 of...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4136: Sensitively and Selectively Detect Biothiols by Using Fluorescence Method and Resonance Light Scattering Technique Simultaneously Molecules doi: 10.3390/molecules24224136 Authors: Yanping Shi Chao Sun Xiaoqi Gao Wei Zhao Nan Zhou In this paper, we designed a new quantitative and qualitive detection method for biothiols by using fluorescence method and resonance light scattering (RLS) technique. Nitrogen doped carbon quantum dots (C/N-dots)...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4134: Constructing Controllable Logic Circuits Based on DNAzyme Activity Molecules doi: 10.3390/molecules24224134 Authors: Fengjie Yang Yuan Liu Bin Wang Changjun Zhou Qiang Zhang Recently, DNA molecules have been widely used to construct advanced logic devices due to their unique properties, such as a simple structure and predictable behavior. In fact, there are still many challenges in the process of building logic circuits. Among them, the scalability...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4133: Hyperbranched Silicone MDTQ Tack Promoters Molecules doi: 10.3390/molecules24224133 Authors: Sijia Zheng Shuai Liang Yang Chen Michael A. Brook Low molecular weight, highly crosslinked silicone resins are widely used as reinforcing agents for highly transparent elastomers and adhesion/tack promoters in gels. The resins are complex mixtures and their structure / property relationships are ill defined. We report the synthesis of a library of 2,...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4135: Photophysical Properties of Spirobifluorene-Based o-Carboranyl Compounds Altered by Structurally Rotating the Carborane Cages Molecules doi: 10.3390/molecules24224135 Authors: Seonah Kim Hyunhee So Ji Hye Lee Hyonseok Hwang Hyoshik Kwon Myung Hwan Park Kang Mun Lee 9,9′-Spirobifluorene-based o-carboranyl compounds C1 and C2 were prepared and fully characterized by multinuclear nuclear magnetic resonance (NMR) spectroscopy and...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4131: The Anti-Serotonin Effect of Parthenolide Derivatives and Standardised Extract from the Leaves of Stizolophus balsamita Molecules doi: 10.3390/molecules24224131 Authors: Joanna Nawrot Marta Napierała Kinga Kaczerowska-Pietrzak Ewa Florek Justyna Gornowicz-Porowska Ewa Pelant Gerard Nowak The presence of dominant active compounds in standardised methanol extract from the leaves of Stizolophus balsamita (S. balsamita) was examined using...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4132: Antioxidants of Natural Plant Origins: From Sources to Food Industry Applications Molecules doi: 10.3390/molecules24224132 Authors: Sofia C. Lourenço Margarida Moldão-Martins Vítor D. Alves In recent years, great interest has been focused on using natural antioxidants in food products, due to studies indicating possible adverse effects that may be related to the consumption of synthetic antioxidants. A variety of plant materials are known to be natural...
Fri Nov 15, 2019 02:00
Molecules, Vol. 24, Pages 4129: Synthesis and Biological Evaluation of Novel Aminochalcones as Potential Anticancer and Antimicrobial Agents Molecules doi: 10.3390/molecules24224129 Authors: Joanna Kozłowska Bartłomiej Potaniec Dagmara Baczyńska Barbara Żarowska Mirosław Anioł A series of 18 aminochalcone derivatives were obtained in yields of 21.5–88.6% by applying the classical Claisen-Schmidt reaction. Compounds 4–9, 14 and 16–18 with 4-ethyl,...
Fri Nov 15, 2019 02:00
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