IJMS, Vol. 20, Pages 5933: The Role of EjSVPs in Flower Initiation in Eriobotrya japonica International Journal of Molecular Sciences doi: 10.3390/ijms20235933 Authors: Yuanyuan Jiang Jiangrong Peng Zhike Zhang Shoukai Lin Shunquan Lin Xianghui Yang Flowering plants have evolved different flowering habits to sustain long-term reproduction. Most woody trees experience dormancy and then bloom in the warm spring, but loquat blooms in the cold autumn and winter. To explore...
02:00
IJMS, Vol. 20, Pages 5932: Optimization of Data-Independent Acquisition Mass Spectrometry for Deep and Highly Sensitive Proteomic Analysis International Journal of Molecular Sciences doi: 10.3390/ijms20235932 Authors: Yusuke Kawashima Eiichiro Watanabe Taichi Umeyama Daisuke Nakajima Masahira Hattori Kenya Honda Osamu Ohara Data-independent acquisition (DIA)-mass spectrometry (MS)-based proteomic analysis overtop the existing data-dependent acquisition (DDA)-MS-based...
02:00
IJMS, Vol. 20, Pages 5929: Establishing a System for Functional Characterization of Full-Length cDNAs of Camellia sinensis International Journal of Molecular Sciences doi: 10.3390/ijms20235929 Authors: Lin Cai Du Zhang Xu Sun Chen : Tea (Camellia sinensis) is enriched with bioactive secondary metabolites, and is one of the most popular nonalcoholic beverages globally. Two tea reference genomes have been reported; however, the functional analysis of tea genes...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5931: IL-1β Induces SOCS2 Expression in Human Dendritic Cells International Journal of Molecular Sciences doi: 10.3390/ijms20235931 Authors: Muamera Sarajlic Theresa Neuper Kim Tamara Föhrenbach Quiroz Sara Michelini Julia Vetter Susanne Schaller Jutta Horejs-Hoeck Dendritic cells (DCs) regulate immunity and inflammation and respond to various stimuli, including cytokines. IL-1β is a key cytokine in the course of both acute and chronic...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5930: Small Molecule Inhibitors Targeting the Heat Shock Protein System of Human Obligate Protozoan Parasites International Journal of Molecular Sciences doi: 10.3390/ijms20235930 Authors: Zininga Shonhai Obligate protozoan parasites of the kinetoplastids and apicomplexa infect human cells to complete their life cycles. Some of the members of these groups of parasites develop in at least two systems, the human host and the insect vector. Survival under the varied...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5927: Ischemic Postconditioning Reduces Reperfusion arrhythmias by Adenosine Receptors and Protein Kinase C Activation but Is Independent of KATP Channels or Connexin 43 International Journal of Molecular Sciences doi: 10.3390/ijms20235927 Authors: Emiliano Raúl Diez Jose Antonio Sánchez Natalia Jorgelina Prado Amira Zulma Ponce Zumino David García-Dorado Roberto Miguel Miatello Antonio Rodríguez-Sinovas Ischemic postconditioning (IPoC) reduces...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5928: WY-14643 Regulates CYP1B1 Expression through Peroxisome Proliferator-Activated Receptor α-Mediated Signaling in Human Breast Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms20235928 Authors: Hwang Won Jin Lee Pham Choi Kang Jeong Human cytochrome P450 1B1 (CYP1B1)-mediated biotransformation of endobiotics and xenobiotics plays an important role in the progression of human breast cancer. In this study, we...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5925: Therapeutic Effect of Iron Citrate in Blocking Calcium Deposition in High Pi-Calcified VSMC: Role of Autophagy and Apoptosis International Journal of Molecular Sciences doi: 10.3390/ijms20235925 Authors: Paola Ciceri Monica Falleni Delfina Tosi Carla Martinelli Stefania Cannizzo Giulia Marchetti Antonella D’Arminio Monforte Gaetano Bulfamante Geoffrey A Block Piergiorgio Messa Mario Cozzolino In chronic kidney disease (CKD), the...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5924: The Precursor for Nerve Growth Factor (proNGF) in Thyroid Cancer Lymph Node Metastases: Correlation with Primary Tumour and Pathological Variables International Journal of Molecular Sciences doi: 10.3390/ijms20235924 Authors: Rowe Dill Faulkner Gedye Paul Tolosa Jones King Smith Hondermarck Metastases in thyroid cancer are associated with aggressive disease and increased patient morbidity, but the factors driving metastatic...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5926: Transplacental Gene Delivery (TPGD) as a Noninvasive Tool for Fetal Gene Manipulation in Mice International Journal of Molecular Sciences doi: 10.3390/ijms20235926 Authors: Nakamura Watanabe Ando Ishihara Sato Transplacental gene delivery (TPGD) is a technique for delivering nucleic acids to fetal tissues via tail-vein injections in pregnant mice. After transplacental transport, administered nucleic acids enter fetal circulation and are distributed...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5922: Transcriptomic and Co-Expression Network Profiling of Shoot Apical Meristem Reveal Contrasting Response to Nitrogen Rate between Indica and Japonica Rice Subspecies International Journal of Molecular Sciences doi: 10.3390/ijms20235922 Authors: Zhang Zhou Huang Mo Lv Gao Chen Yin Ju Dong Zhou Yang Li Wang Huang Yao Reducing nitrogen (N) input is a key measure to achieve a sustainable rice production...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5921: Structure of Staphylococcal Enterotoxin N: Implications for Binding Properties to Its Cellular Proteins International Journal of Molecular Sciences doi: 10.3390/ijms20235921 Authors: Zeng Liu Han Staphylococcus aureus strains produce a unique family of immunostimulatory exotoxins termed as bacterial superantigens (SAgs), which cross-link major histocompatibility complex class II (MHC II) molecule and T-cell receptor (TCR) to stimulate large numbers...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5923: Comparative Transcriptomics of Flammulina filiformis Suggests a High CO2 Concentration Inhibits Early Pileus Expansion by Decreasing Cell Division Control Pathways International Journal of Molecular Sciences doi: 10.3390/ijms20235923 Authors: Jun-Jie Yan Zong-Jun Tong Yuan-Yuan Liu Yi-Ning Li Chen Zhao Irum Mukhtar Yong-Xin Tao Bing-Zhi Chen You-Jin Deng Bao-Gui Xie Carbon dioxide is commonly used as one of the significant environmental...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5920: Impact of Glucoraphanin-Mediated Activation of Nrf2 on Non-Alcoholic Fatty Liver Disease with a Focus on Mitochondrial Dysfunction International Journal of Molecular Sciences doi: 10.3390/ijms20235920 Authors: Xu Nagata Ota Non-alcoholic fatty liver disease (NAFLD) is a common disease in Western nations and ranges in severity from steatosis to steatohepatitis (NASH). NAFLD is a genetic-environmental-metabolic stress-related disease of unclear pathogenesis....
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5919: McArdle Disease: New Insights into Its Underlying Molecular Mechanisms International Journal of Molecular Sciences doi: 10.3390/ijms20235919 Authors: Llavero Arrazola Sastre Luque Montoro Gálvez Lacerda Parada Zugaza McArdle disease, also known as glycogen storage disease type V (GSDV), is characterized by exercise intolerance, the second wind phenomenon, and high serum creatine kinase activity. Here, we recapitulate PYGM mutations...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5918: Waste Autochthonous Tuscan Olive Leaves (Olea europaea var. Olivastra seggianese) as Antioxidant Source for Biomedicine International Journal of Molecular Sciences doi: 10.3390/ijms20235918 Authors: De la Ossa Felice Azimi Salsano Digiacomo Macchia Danti Di Stefano Olive leaf extract (OLE) can be obtained as biowaste and is extensively used a food supplement and an over-the-counter drug for its beneficial effects. New studies have...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5917: Electroacupuncture Alleviates Paclitaxel-Induced Peripheral Neuropathic Pain in Rats via Suppressing TLR4 Signaling and TRPV1 Upregulation in Sensory Neurons International Journal of Molecular Sciences doi: 10.3390/ijms20235917 Authors: Yuanyuan Li Chengyu Yin Xiaojie Li Boyu Liu Jie Wang Xiaoli Zheng Xiaomei Shao Yi Liang Junying Du Jianqiao Fang Boyi Liu Paclitaxel-induced peripheral neuropathy is a common adverse effect during...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5916: Trypanocidal Mechanism of Action and in silico Studies of p-Coumaric Acid Derivatives International Journal of Molecular Sciences doi: 10.3390/ijms20235916 Authors: Susiany P. Lopes Yunierkis P. Castillo Marilia L. Monteiro Ramon R. P. P. B. de Menezes Reinaldo N. Almeida Alice M. C. Martins Damião P. de Sousa Trypanosoma species are responsible for chronic and systemic infections in millions of people around the world, compromising life quality,...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5915: A Combined Linkage and GWAS Analysis Identifies QTLs Linked to Soybean Seed Protein and Oil Content International Journal of Molecular Sciences doi: 10.3390/ijms20235915 Authors: Tengfei Zhang Tingting Wu Liwei Wang Bingjun Jiang Caixin Zhen Shan Yuan Wensheng Hou Cunxiang Wu Tianfu Han Shi Sun Soybean is an excellent source of vegetable protein and edible oil. Understanding the genetic basis of protein and oil content will improve...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5914: Emetine Synergizes with Cisplatin to Enhance Anti-Cancer Efficacy against Lung Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms20235914 Authors: Ti-Hui Wu Shan-Yueh Chang Yu-Lueng Shih Tsai-Wang Huang Hung Chang Ya-Wen Lin Cisplatin is still the primary therapeutic choice for advanced lung cancers without driver mutations. The occurrence of cisplatin resistance is a major clinical problem in lung cancer treatment. The...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5913: Model Optimization and In Silico Analysis of Potential Dipeptidyl Peptidase IV Antagonists from GC-MS Identified Compounds in Nauclea latifolia Leaf Extracts International Journal of Molecular Sciences doi: 10.3390/ijms20235913 Authors: Franklyn Nonso Iheagwam Olubanke Olujoke Ogunlana Shalom Nwodo Chinedu Dipeptidyl peptidase IV (DPP-IV) is a pharmacotherapeutic target in type 2 diabetes. Inhibitors of this enzyme constitute a new class of drugs used...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5911: Global Proteomic Analysis Reveals Widespread Lysine Succinylation in Rice Seedlings International Journal of Molecular Sciences doi: 10.3390/ijms20235911 Authors: Kai Zhang Yehui Xiong Wenxian Sun Guo-Liang Wang Wende Liu Lysine succinylation (Ksu) is a dynamic and reversible post-translational modification that plays an important role in many biological processes. Although recent research has analyzed Ksu plant proteomes, little is known about...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5912: Quantitative Trait Module-Based Genetic Analysis of Alzheimer’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms20235912 Authors: Shaoxun Yuan Haitao Li Jianming Xie Xiao Sun The pathological features of Alzheimer’s Disease (AD) first appear in the medial temporal lobe and then in other brain structures with the development of the disease. In this work, we investigated the association between genetic loci and subcortical...
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5909: Functional Analysis of the Soybean GmCDPK3 Gene Responding to Drought and Salt Stresses International Journal of Molecular Sciences doi: 10.3390/ijms20235909 Authors: Dan Wang Yuan-Xia Liu Qian Yu Shu-Ping Zhao Juan-Ying Zhao Jing-Na Ru Xin-You Cao Zheng-Wu Fang Jun Chen Yong-Bin Zhou Ming Chen You-Zhi Ma Zhao-Shi Xu Jin-Hao Lan Plants have a series of response mechanisms to adapt when they are subjected to external stress....
Mon Nov 25, 2019 02:00
IJMS, Vol. 20, Pages 5910: Transcriptome Analysis of Salt-Sensitive and Tolerant Genotypes Reveals Salt-Tolerance Metabolic Pathways in Sugar Beet International Journal of Molecular Sciences doi: 10.3390/ijms20235910 Authors: Gui Geng Chunhua Lv Piergiorgio Stevanato Renren Li Hui Liu Lihua Yu Yuguang Wang Soil salinization is a common environmental problem that seriously affects the yield and quality of crops. Sugar beet (Beta vulgaris L.), one of the main sugar crops...
Mon Nov 25, 2019 02:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου