Πέμπτη 7 Νοεμβρίου 2019


IJMS, Vol. 20, Pages 5566: Identification and Characterization of a Fatty Acid- and Retinoid-Binding Protein Gene (Ar-far-1) from the Chrysanthemum Foliar Nematode, Aphelenchoides ritzemabosi
IJMS, Vol. 20, Pages 5566: Identification and Characterization of a Fatty Acid- and Retinoid-Binding Protein Gene (Ar-far-1) from the Chrysanthemum Foliar Nematode, Aphelenchoides ritzemabosi International Journal of Molecular Sciences doi: 10.3390/ijms20225566 Authors: Shan-Wen Ding Dong-Wei Wang Yu Xiang Chun-Ling Xu Hui Xie The chrysanthemum foliar nematode (CFN), Aphelenchoides ritzemabosi, is a migratory, plant-parasitic nematode that is widely distributed and infects...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5562: Functional Dissection of the Chickpea (Cicer arietinum L.) Stay-Green Phenotype Associated with Molecular Variation at an Ortholog of Mendel’s I Gene for Cotyledon Color: Implications for Crop Production and Carotenoid Biofortification
IJMS, Vol. 20, Pages 5562: Functional Dissection of the Chickpea (Cicer arietinum L.) Stay-Green Phenotype Associated with Molecular Variation at an Ortholog of Mendel’s I Gene for Cotyledon Color: Implications for Crop Production and Carotenoid Biofortification International Journal of Molecular Sciences doi: 10.3390/ijms20225562 Authors: Kaliamoorthy Sivasakthi Edward Marques Ng’andwe Kalungwana Noelia Carrasquilla-Garcia Peter L. Chang Emily M. Bergmann Erika Bueno Matilde...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5564: The Pathogenic TSH β-subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR
IJMS, Vol. 20, Pages 5564: The Pathogenic TSH β-subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR International Journal of Molecular Sciences doi: 10.3390/ijms20225564 Authors: Kalveram Kleinau Szymańska Scheerer Rivero-Müller Grüters-Kieslich Biebermann 1) Background: Central congenital hypothyroidism (CCH) is a rare endocrine disorder that can be caused by mutations in the β-subunit of thyrotropin (TSHB). The TSHB mutation C105Vfs114X...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5565: Systematic Enzyme Mapping of Cellular Metabolism by Phasor-Analyzed Label-Free NAD(P)H Fluorescence Lifetime Imaging
IJMS, Vol. 20, Pages 5565: Systematic Enzyme Mapping of Cellular Metabolism by Phasor-Analyzed Label-Free NAD(P)H Fluorescence Lifetime Imaging International Journal of Molecular Sciences doi: 10.3390/ijms20225565 Authors: Leben Köhler Radbruch Hauser Niesner In the past years, cellular metabolism of the immune system experienced a revival, as it has become clear that it is not merely responsible for the cellular energy supply, but also impacts on many signaling pathways...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5563: Inflammation and Coronary Microvascular Dysfunction in Autoimmune Rheumatic Diseases
IJMS, Vol. 20, Pages 5563: Inflammation and Coronary Microvascular Dysfunction in Autoimmune Rheumatic Diseases International Journal of Molecular Sciences doi: 10.3390/ijms20225563 Authors: Elisabetta Zanatta Claudia Colombo Gianpiero D’Amico Thomas d’Humières Carlo Dal Lin Francesco Tona Autoimmune rheumatic diseases (ARDs) form a heterogeneous group of disorders that include systemic lupus erythematosus (SLE), systemic sclerosis (SSc), rheumatoid arthritis (RA), idiopathic...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5561: The Impact of Hypoxia on the Host-Pathogen Interaction between Neutrophils and Staphylococcus aureus
IJMS, Vol. 20, Pages 5561: The Impact of Hypoxia on the Host-Pathogen Interaction between Neutrophils and Staphylococcus aureus International Journal of Molecular Sciences doi: 10.3390/ijms20225561 Authors: Natalia H Hajdamowicz Rebecca C Hull Simon J Foster Alison M Condliffe Neutrophils are key to host defence, and impaired neutrophil function predisposes to infection with an array of pathogens, with Staphylococcus aureus a common and sometimes life-threatening problem in...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5560: Water Extract of Cryphaea heteromalla (Hedw.) D. Mohr Bryophyte as a Natural Powerful Source of Biologically Active Compounds
IJMS, Vol. 20, Pages 5560: Water Extract of Cryphaea heteromalla (Hedw.) D. Mohr Bryophyte as a Natural Powerful Source of Biologically Active Compounds International Journal of Molecular Sciences doi: 10.3390/ijms20225560 Authors: Fiorenza Provenzano Jesús Lozano Sánchez Estella Rao Radha Santonocito Lorena Anna Ditta Isabel Borrás Linares Rosa Passantino Patrizia Campisi Maria Giovanna Dia Maria Assunta Costa Antonio Segura-Carretero Pier Luigi San Biagio...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5558: Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation
IJMS, Vol. 20, Pages 5558: Identification of Novel 1,3,5-Triphenylbenzene Derivative Compounds as Inhibitors of Hen Lysozyme Amyloid Fibril Formation International Journal of Molecular Sciences doi: 10.3390/ijms20225558 Authors: Hassan Ramshini Reza Tayebee Alessandra Bigi Francesco Bemporad Cristina Cecchi Fabrizio Chiti Deposition of soluble proteins as insoluble amyloid fibrils is associated with a number of pathological states. There is a growing interest in the identification...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5559: Anti-Cancer Activity of a 5-Aminopyrazole Derivative Lead Compound (BC-7) and Potential Synergistic Cytotoxicity with Cisplatin against Human Cervical Cancer Cells
IJMS, Vol. 20, Pages 5559: Anti-Cancer Activity of a 5-Aminopyrazole Derivative Lead Compound (BC-7) and Potential Synergistic Cytotoxicity with Cisplatin against Human Cervical Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms20225559 Authors: Bresler Swanepoel George Mihai Nitulescu Octavian Tudorel Olaru Luanne Venables Maryna van de Venter The use of some very well-known chemotherapeutic agents, such as cisplatin, is limited by toxicity in normal...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5557: Comparatively Barcoded Chromosomes of Brachypodium Perennials Tell the Story of Their Karyotype Structure and Evolution
IJMS, Vol. 20, Pages 5557: Comparatively Barcoded Chromosomes of Brachypodium Perennials Tell the Story of Their Karyotype Structure and Evolution International Journal of Molecular Sciences doi: 10.3390/ijms20225557 Authors: Joanna Lusinska Alexander Betekhtin Diana Lopez-Alvarez Pilar Catalan Glyn Jenkins Elzbieta Wolny Robert Hasterok The Brachypodium genus is an informative model system for studying grass karyotype organization. Previous studies of a limited number...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5556: Degradation of High Energy Materials Using Biological Reduction: A Rational Way to Reach Bioremediation
IJMS, Vol. 20, Pages 5556: Degradation of High Energy Materials Using Biological Reduction: A Rational Way to Reach Bioremediation International Journal of Molecular Sciences doi: 10.3390/ijms20225556 Authors: Stephanie Aguero Raphaël Terreux Explosives molecules have been widely used since World War II, leading to considerable contamination of soil and groundwater. Recently, bioremediation has emerged as an environmentally friendly approach to solve such contamination issues. However,...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5555: Prostaglandin E2 Induces Skin Aging via E-Prostanoid 1 in Normal Human Dermal Fibroblasts
IJMS, Vol. 20, Pages 5555: Prostaglandin E2 Induces Skin Aging via E-Prostanoid 1 in Normal Human Dermal Fibroblasts International Journal of Molecular Sciences doi: 10.3390/ijms20225555 Authors: Joong Hyun Shim Collagen type I production decreases with aging, leading to wrinkles and impaired skin function. Prostaglandin E2 (PGE2), a lipid-derived signaling molecule produced from arachidonic acid by cyclo-oxygenase, inhibits collagen production, and induces matrix metallopeptidase 1...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5554: RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells
IJMS, Vol. 20, Pages 5554: RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells International Journal of Molecular Sciences doi: 10.3390/ijms20225554 Authors: Xuan Su Yue Jin Yan Shen Il-man Kim Neal L. Weintraub Yaoliang Tang Cardiac mesenchymal stem cells (C-MSC) play a key role in maintaining normal cardiac function under physiological and pathological conditions. Glycolysis and mitochondrial oxidative...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5553: Carotenoids as Novel Therapeutic Molecules Against Neurodegenerative Disorders: Chemistry and Molecular Docking Analysis
IJMS, Vol. 20, Pages 5553: Carotenoids as Novel Therapeutic Molecules Against Neurodegenerative Disorders: Chemistry and Molecular Docking Analysis International Journal of Molecular Sciences doi: 10.3390/ijms20225553 Authors: Johant Lakey-Beitia Jagadeesh Kumar D. Muralidhar L. Hegde K.S. Rao Alzheimer’s disease (AD) is the most devastating neurodegenerative disorder that affects the aging population worldwide. Endogenous and exogenous factors are involved in triggering...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5551: Angiotensin III Induces JAK2/STAT3 Leading to IL-6 Production in Rat Vascular Smooth Muscle Cells
IJMS, Vol. 20, Pages 5551: Angiotensin III Induces JAK2/STAT3 Leading to IL-6 Production in Rat Vascular Smooth Muscle Cells International Journal of Molecular Sciences doi: 10.3390/ijms20225551 Authors: Ahmed Z. Alanazi Michelle A. Clark The Janus kinase-2/ signal transducer and activators of transcription-3 (JAK2/STAT3) pathway and interleukin-6 (IL-6) are pleiotropic signal transduction systems that are responsible for induction of many cytokines and growth factors. It is unknown...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5550: Analysis of Functional Domains in Rho5, the Yeast Homolog of Human Rac1 GTPase, in Oxidative Stress Response
IJMS, Vol. 20, Pages 5550: Analysis of Functional Domains in Rho5, the Yeast Homolog of Human Rac1 GTPase, in Oxidative Stress Response International Journal of Molecular Sciences doi: 10.3390/ijms20225550 Authors: Carolin Sterk Lauren Gräber Hans-Peter Schmitz Jürgen J. Heinisch The small GTPase Rho5 of Saccharomyces cerevisiae is required for proper regulation of different signaling pathways, which includes the response to cell wall, osmotic, nutrient, and oxidative stress....
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5546: Ammonium Gemini Surfactants Form Complexes with Model Oligomers of siRNA and dsDNA
IJMS, Vol. 20, Pages 5546: Ammonium Gemini Surfactants Form Complexes with Model Oligomers of siRNA and dsDNA International Journal of Molecular Sciences doi: 10.3390/ijms20225546 Authors: Weronika Andrzejewska Michalina Wilkowska Andrzej Skrzypczak Maciej Kozak Dimeric cationic surfactants (gemini-type) are a group of amphiphilic compounds with potential use in gene therapy as effective carriers for nucleic acid transfection (i.e., siRNA, DNA, and plasmid DNA). Our studies...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5547: MicroRNAs as Potential Biomarkers in Atherosclerosis
IJMS, Vol. 20, Pages 5547: MicroRNAs as Potential Biomarkers in Atherosclerosis International Journal of Molecular Sciences doi: 10.3390/ijms20225547 Authors: Alexey Churov Volha Summerhill Andrey Grechko Varvara Orekhova Alexander Orekhov Atherosclerosis is a complex multifactorial disease that, despite advances in lifestyle management and drug therapy, remains to be the major cause of high morbidity and mortality rates from cardiovascular diseases (CVDs) in industrialized...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5552: Wnt Signaling and Biological Therapy in Rheumatoid Arthritis and Spondyloarthritis
IJMS, Vol. 20, Pages 5552: Wnt Signaling and Biological Therapy in Rheumatoid Arthritis and Spondyloarthritis International Journal of Molecular Sciences doi: 10.3390/ijms20225552 Authors: Daniela Cici Addolorata Corrado Cinzia Rotondo Francesco P. Cantatore The Wnt signaling pathway plays a key role in several biological processes, such as cellular proliferation and tissue regeneration, and its dysregulation is involved in the pathogenesis of many autoimmune diseases. Several...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5548: GnRH Antagonists Produce Differential Modulation of the Signaling Pathways Mediated by GnRH Receptors
IJMS, Vol. 20, Pages 5548: GnRH Antagonists Produce Differential Modulation of the Signaling Pathways Mediated by GnRH Receptors International Journal of Molecular Sciences doi: 10.3390/ijms20225548 Authors: Samantha Sperduti Silvia Limoncella Clara Lazzaretti Elia Paradiso Laura Riccetti Sara Turchi Ilaria Ferrigno Jessika Bertacchini Carla Palumbo Francesco Potì Salvatore Longobardi Robert P. Millar Manuela Simoni Claire L. Newton Livio Casarini...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
IJMS, Vol. 20, Pages 5549: Omega-3 Polyunsaturated Fatty Acids and Stroke Burden
IJMS, Vol. 20, Pages 5549: Omega-3 Polyunsaturated Fatty Acids and Stroke Burden International Journal of Molecular Sciences doi: 10.3390/ijms20225549 Authors: Yuji Ueno Nobukazu Miyamoto Kazuo Yamashiro Ryota Tanaka Nobutaka Hattori Stroke is a major leading cause of death and disability worldwide. N-3 polyunsaturated fatty acids (PUFAs) including eicosapentaenoic acid and docosahexaenoic acid have potent anti-inflammatory effects, reduce platelet aggregation, and regress...
International Journal of Molecular Sciences
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1912: The Association between SOCS1−1656G>A Polymorphism, Insulin Resistance and Obesity in Nonalcoholic Fatty Liver Disease (NAFLD) Patients
JCM, Vol. 8, Pages 1912: The Association between SOCS1−1656G>A Polymorphism, Insulin Resistance and Obesity in Nonalcoholic Fatty Liver Disease (NAFLD) Patients Journal of Clinical Medicine doi: 10.3390/jcm8111912 Authors: Agnieszka Kempinska-Podhorodecka Ewa Wunsch Piotr Milkiewicz Ewa Stachowska Malgorzata Milkiewicz Suppressor of cytokine signaling (SOCS) proteins prevent uncontrolled cytokine signaling and appear to play a role in the pathological processes behind...
Journal of Clinical Medicine
02:00
JCM, Vol. 8, Pages 1911: Efficacy and Feasibility of Salvage Re-Irradiation with CyberKnife for In-Field Neck Lymph Node Recurrence: A Retrospective Study
JCM, Vol. 8, Pages 1911: Efficacy and Feasibility of Salvage Re-Irradiation with CyberKnife for In-Field Neck Lymph Node Recurrence: A Retrospective Study Journal of Clinical Medicine doi: 10.3390/jcm8111911 Authors: Kobayashi Sato Saitoh Oike Nakajima Noda Kato Iwanaga Shimizu Nakano Neck lymph node (LN) recurrence in the irradiated field represents an important aspect of treatment failure after primary radiotherapy owing to the lack of a standard...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1909: Treatment of Peri-implantitis—Electrolytic Cleaning Versus Mechanical and Electrolytic Cleaning—A Randomized Controlled Clinical Trial—Six-Month Results
JCM, Vol. 8, Pages 1909: Treatment of Peri-implantitis—Electrolytic Cleaning Versus Mechanical and Electrolytic Cleaning—A Randomized Controlled Clinical Trial—Six-Month Results Journal of Clinical Medicine doi: 10.3390/jcm8111909 Authors: Schlee Rathe Brodbeck Ratka Weigl Zipprich Objectives: The present randomized clinical trial assesses the six-month outcomes following surgical regenerative therapy of periimplantitis lesions using either an electrolytic method...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1910: Systematic Balance Exercises Influence Cortical Activation and Serum BDNF Levels in Older Adults
JCM, Vol. 8, Pages 1910: Systematic Balance Exercises Influence Cortical Activation and Serum BDNF Levels in Older Adults Journal of Clinical Medicine doi: 10.3390/jcm8111910 Authors: Kubica Szymura Domagalik Golda Wiecek Fafrowicz Marek Pera : We sought to investigate whether systematic balance training modulates brain area activity responsible for postural control and influence brain-derived neurotrophic factor (BDNF) mRNA protein expression. Seventy-four...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1906: Mortality Prediction of Septic Patients in the Emergency Department Based on Machine Learning
JCM, Vol. 8, Pages 1906: Mortality Prediction of Septic Patients in the Emergency Department Based on Machine Learning Journal of Clinical Medicine doi: 10.3390/jcm8111906 Authors: Jau-Woei Perng I-Hsi Kao Chia-Te Kung Shih-Chiang Hung Yi-Horng Lai Chih-Min Su In emergency departments, the most common cause of death associated with suspected infected patients is sepsis. In this study, deep learning algorithms were used to predict the mortality of suspected infected patients...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1908: Predictive Validity of the qSOFA Score for Sepsis in Adults with Community-Onset Staphylococcal Infection in Thailand
JCM, Vol. 8, Pages 1908: Predictive Validity of the qSOFA Score for Sepsis in Adults with Community-Onset Staphylococcal Infection in Thailand Journal of Clinical Medicine doi: 10.3390/jcm8111908 Authors: Supaksh Gupta Kristina E. Rudd Sarunporn Tandhavanant Pornpan Suntornsut Ploenchan Chetchotisakd Derek C. Angus Sharon J. Peacock Narisara Chantratita Timothy Eoin West The quick sequential organ failure assessment (qSOFA) score has had limited validation in...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1907: Non-Pharmacological Therapeutic Options for Liver Metastases in Advanced Neuroendocrine Tumors
JCM, Vol. 8, Pages 1907: Non-Pharmacological Therapeutic Options for Liver Metastases in Advanced Neuroendocrine Tumors Journal of Clinical Medicine doi: 10.3390/jcm8111907 Authors: Solène Dermine Lola-Jade Palmieri Julie Lavolé Amélie Barré Antony Dohan Einas Abou Ali Anne-Ségolène Cottereau Sébastien Gaujoux Catherine Brezault Stanislas Chaussade Romain Coriat The incidence of liver metastasis in digestive neuroendocrine tumors is high. Their presence...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1900: Memory Complaint Is a Surrogate for Memory Decline in the Middle-Aged: A Register-Based Study
JCM, Vol. 8, Pages 1900: Memory Complaint Is a Surrogate for Memory Decline in the Middle-Aged: A Register-Based Study Journal of Clinical Medicine doi: 10.3390/jcm8111900 Authors: Yah-Yuan Wu Wen-Chuin Hsu Yu-Hua Huang Wei-Min Ho Yi-Chun Chen Memory complaint is one of the earliest symptoms of dementia. The causes and prognosis of memory complaint in the middle-aged population remain largely unknown. We reviewed the register-based data of 2129 patients with memory complaints....
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1904: NK Cell Reconstitution in Paediatric Leukemic Patients after T-Cell-Depleted HLA-Haploidentical Haematopoietic Stem Cell Transplantation Followed by the Reinfusion of iCasp9-Modified Donor T Cells
JCM, Vol. 8, Pages 1904: NK Cell Reconstitution in Paediatric Leukemic Patients after T-Cell-Depleted HLA-Haploidentical Haematopoietic Stem Cell Transplantation Followed by the Reinfusion of iCasp9-Modified Donor T Cells Journal of Clinical Medicine doi: 10.3390/jcm8111904 Authors: Helena Stabile Paolo Nisti Cinzia Fionda Daria Pagliara Stefania Gaspari Franco Locatelli Angela Santoni Angela Gismondi T-cell-depleted (TCD) human leukocyte antigen (HLA) haploidentical...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1903: Expression of EEF1A1 Is Associated with Prognosis of Patients with Colon Adenocarcinoma
JCM, Vol. 8, Pages 1903: Expression of EEF1A1 Is Associated with Prognosis of Patients with Colon Adenocarcinoma Journal of Clinical Medicine doi: 10.3390/jcm8111903 Authors: Eun kyo Joung Jiyoung Kim Nara Yoon Lee-so Maeng Ji Hoon Kim Sungsoo Park Keunsoo Kang Jeong Seon Kim Young-Ho Ahn Yoon Ho Ko Jae Ho Byun Ji Hyung Hong Background: The prognostic role of the translational factor, elongation factor-1 alpha 1 (EEF1A1), in colon cancer is unclear. Objectives:...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1902: Early Post-Operative Intervention of Whole-Body Vibration in Patients After Total Knee Arthroplasty: A Pilot Study
JCM, Vol. 8, Pages 1902: Early Post-Operative Intervention of Whole-Body Vibration in Patients After Total Knee Arthroplasty: A Pilot Study Journal of Clinical Medicine doi: 10.3390/jcm8111902 Authors: Yu-Hsuan Hsiao Song-Hsiung Chien Hung-Pin Tu Jimmy Chun-Ming Fu Shih-Ting Tsai Ying-Shan Chen Yi-Jen Chen Chia-Hsin Chen (1) Background: Knee osteoarthritis causes pain, weakness, muscle atrophy, and disability. The application of whole-body vibration in patients with...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1905: Comment from the Editor on the Special Issue “Head and Neck Critical Illness: Basic and Clinical Research Implications”
JCM, Vol. 8, Pages 1905: Comment from the Editor on the Special Issue “Head and Neck Critical Illness: Basic and Clinical Research Implications” Journal of Clinical Medicine doi: 10.3390/jcm8111905 Authors: Hiroyuki Tomita While oncogenic mutations of head and neck squamous cell carcinomas (HNSCC) in head and neck malignancies are uncommon, analysis using next-generation sequencing (NGS) technologies is growing. Further, single-cell analysis is being developed to overcome cancer cell...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1899: Urinary Biomarkers α-GST and π-GST for Evaluation and Monitoring in Living and Deceased Donor Kidney Grafts
JCM, Vol. 8, Pages 1899: Urinary Biomarkers α-GST and π-GST for Evaluation and Monitoring in Living and Deceased Donor Kidney Grafts Journal of Clinical Medicine doi: 10.3390/jcm8111899 Authors: Shadi Katou Brigitta Globke M. Haluk Morgul Thomas Vogel Benjamin Struecker Natalie Maureen Otto Anja Reutzel-Selke Marion Marksteiner Jens G. Brockmann Andreas Pascher Volker Schmitz The aim of this study was to analyze the value of urine α- and π-GST...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1898: Clinical Characteristics and Outcomes of Surgically Resected Solitary Pulmonary Nodules Due to Nontuberculous Mycobacterial Infections
JCM, Vol. 8, Pages 1898: Clinical Characteristics and Outcomes of Surgically Resected Solitary Pulmonary Nodules Due to Nontuberculous Mycobacterial Infections Journal of Clinical Medicine doi: 10.3390/jcm8111898 Authors: Yeonseok Choi Byung Woo Jhun Jhingook Kim Hee Jae Huh Nam Yong Lee Background: Limited data are available regarding the detailed characteristics and outcomes of surgically resected nontuberculous mycobacterial (NTM) granulomas. Methods: We evaluated the...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1901: Cross-Sectional and Longitudinal Associations between Peak Expiratory Flow and Frailty in Older Adults
JCM, Vol. 8, Pages 1901: Cross-Sectional and Longitudinal Associations between Peak Expiratory Flow and Frailty in Older Adults Journal of Clinical Medicine doi: 10.3390/jcm8111901 Authors: Caterina Trevisan Debora Rizzuto Stefania Maggi Giuseppe Sergi Anna-Karin Welmer Davide Liborio Vetrano Peak expiratory flow (PEF) has been linked to several health-related outcomes in older people, but its association with frailty is still unclear. This study investigates the association...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
JCM, Vol. 8, Pages 1897: Impact of the Total Number of Carotid Plaques on the Outcome of Ischemic Stroke Patients with Atrial Fibrillation
JCM, Vol. 8, Pages 1897: Impact of the Total Number of Carotid Plaques on the Outcome of Ischemic Stroke Patients with Atrial Fibrillation Journal of Clinical Medicine doi: 10.3390/jcm8111897 Authors: Hyungjong Park Minho Han Young Dae Kim Joonsang Yoo Hye Sun Lee Jin Kyo Choi Ji Hoe Heo Hyo Suk Nam Background: Atrial fibrillation (AF) shares several risk factors with atherosclerosis. We investigated the association between total carotid plaque number (TPN) and long-term...
Journal of Clinical Medicine
Thu Nov 07, 2019 02:00
Medicina, Vol. 55, Pages 729: Comparison of the Therapeutic Efficacies of Topical Rivoceranib and Topical Bevacizumab in a Murine Model of Corneal Neovascularization
Medicina, Vol. 55, Pages 729: Comparison of the Therapeutic Efficacies of Topical Rivoceranib and Topical Bevacizumab in a Murine Model of Corneal Neovascularization Medicina doi: 10.3390/medicina55110729 Authors: Hyeon Jeong Yoon Je Moon Woo Yong Sok Ji Kyung Chul Yoon Background and Objectives: Corneal neovasculariziation (CNV) is a serious vision-threatening complication; however, all therapeutics have their clinical limitations. The aim of this study is to investigate the...
Medicina
Thu Nov 07, 2019 02:00
Medicina, Vol. 55, Pages 728: Mature miR-99a Upregulation in the Amniotic Fluid Samples from Female Fetus Down Syndrome Pregnancies: A Pilot Study
Medicina, Vol. 55, Pages 728: Mature miR-99a Upregulation in the Amniotic Fluid Samples from Female Fetus Down Syndrome Pregnancies: A Pilot Study Medicina doi: 10.3390/medicina55110728 Authors: Anda-Cornelia Vizitiu Danae Stambouli Anca-Gabriela Pavel Maria-Cezara Muresan Diana Maria Anastasiu Cristina Bejinar Anda Alexa Catalin Marian Ioan Ovidiu Sirbu Laurentiu Sima Background and Objective: Although Down syndrome is the most frequent aneuploidy, its pathogenic...
Medicina
Thu Nov 07, 2019 02:00

Metabolites, Vol. 9, Pages 271: Caucasian Gentiana Species: Untargeted LC-MS Metabolic Profiling, Antioxidant and Digestive Enzyme Inhibiting Activity of Six Plants
Metabolites, Vol. 9, Pages 271: Caucasian Gentiana Species: Untargeted LC-MS Metabolic Profiling, Antioxidant and Digestive Enzyme Inhibiting Activity of Six Plants Metabolites doi: 10.3390/metabo9110271 Authors: Olennikov Gadimli Isaev Kashchenko Prokopyev Kataeva Chirikova Vennos The members of Gentiana genus are widely distributed in the Caucasus region where they are used as phytoremedies, but they still have not been studied for their chemical composition...
Metabolites
Thu Nov 07, 2019 02:00
Metabolites, Vol. 9, Pages 270: Metabolomics Test Materials for Quality Control: A Study of a Urine Materials Suite
Metabolites, Vol. 9, Pages 270: Metabolomics Test Materials for Quality Control: A Study of a Urine Materials Suite Metabolites doi: 10.3390/metabo9110270 Authors: Daniel W. Bearden David A. Sheen Yamil Simón-Manso Bruce A. Benner Werickson F. C. Rocha Niksa Blonder Katrice A. Lippa Richard D. Beger Laura K. Schnackenberg Jinchun Sun Khyati Y. Mehta Amrita K. Cheema Haiwei Gu Ramesh Marupaka G. A. Nagana Gowda Daniel Raftery There is a lack...
Metabolites
Thu Nov 07, 2019 02:00
Metabolites, Vol. 9, Pages 269: Untargeted Urinary 1H NMR-Based Metabolomic Pattern as a Potential Platform in Breast Cancer Detection
Metabolites, Vol. 9, Pages 269: Untargeted Urinary 1H NMR-Based Metabolomic Pattern as a Potential Platform in Breast Cancer Detection Metabolites doi: 10.3390/metabo9110269 Authors: Catarina L. Silva Ana Olival Rosa Perestrelo Pedro Silva Helena Tomás José S. Câmara Breast cancer (BC) remains the second leading cause of death among women worldwide. An emerging approach based on the identification of endogenous metabolites (EMs) and the establishment of the metabolomic...
Metabolites
Thu Nov 07, 2019 02:00
Microorganisms, Vol. 7, Pages 538: Mitochondria-Mediated Programmed Cell Death in Saccharomyces cerevisiae Induced by Betulinic Acid Is Accelerated by the Deletion of PEP4 Gene
Microorganisms, Vol. 7, Pages 538: Mitochondria-Mediated Programmed Cell Death in Saccharomyces cerevisiae Induced by Betulinic Acid Is Accelerated by the Deletion of PEP4 Gene Microorganisms doi: 10.3390/microorganisms7110538 Authors: Lu Shu Lou Chen In this work, using Saccharomyces cerevisiae as a model, we showed that BetA could inhibitcell proliferation and lead to lethal cytotoxicity accompanying programmed cell death (PCD).Interestingly, it was found that vacuolar...
Microorganisms
Thu Nov 07, 2019 02:00
Microorganisms, Vol. 7, Pages 537: A Pyrrhic Victory: The PMN Response to Ocular Bacterial Infections
Microorganisms, Vol. 7, Pages 537: A Pyrrhic Victory: The PMN Response to Ocular Bacterial Infections Microorganisms doi: 10.3390/microorganisms7110537 Authors: Erin T. Livingston Md Huzzatul Mursalin Michelle C. Callegan Some tissues of the eye are susceptible to damage due to their exposure to the outside environment and inability to regenerate. Immune privilege, although beneficial to the eye in terms of homeostasis and protection, can be harmful when breached or when an aberrant...
Microorganisms
Thu Nov 07, 2019 02:00
Microorganisms, Vol. 7, Pages 536: Risk Comparison of the Diarrheal and Emetic Type of Bacillus cereus in Tofu
Microorganisms, Vol. 7, Pages 536: Risk Comparison of the Diarrheal and Emetic Type of Bacillus cereus in Tofu Microorganisms doi: 10.3390/microorganisms7110536 Authors: Mi Jin Kwon Chae Lim Lee Ki Sun Yoon We investigated the ability of biofilm formation, survival, and behavior of diarrheal and emetic Bacillus cereus vegetative cells and spores in tofu. Both diarrheal and emetic B. cereus did not proliferate at a temperature below 9 °C in tofu. However, the emetic B. cereus...
Microorganisms
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4046: Management of Exciton for Highly-Efficient Hybrid White Organic Light-Emitting Diodes with a Non-Doped Blue Emissive Layer
Molecules, Vol. 24, Pages 4046: Management of Exciton for Highly-Efficient Hybrid White Organic Light-Emitting Diodes with a Non-Doped Blue Emissive Layer Molecules doi: 10.3390/molecules24224046 Authors: Wei Luo Xing Chen Shuang-Qiao Sun Yi-Jie Zhang Tong-Tong Wang Liang-Sheng Liao Man-Keung Fung Hybrid white organic light-emitting diodes (WOLEDs) have drawn great attention both for display and solid-state lighting purposes because of the combined advantages of desirable...
Molecules
02:00
Molecules, Vol. 24, Pages 4045: Portable Power Generation for Remote Areas Using Hydrogen Generated via Maleic Acid-Promoted Hydrolysis of Ammonia Borane
Molecules, Vol. 24, Pages 4045: Portable Power Generation for Remote Areas Using Hydrogen Generated via Maleic Acid-Promoted Hydrolysis of Ammonia Borane Molecules doi: 10.3390/molecules24224045 Authors: Taylor B. Groom Jason R. Gabl Timothée L. Pourpoint A significant drawback to ammonia borane as a hydrogen storage material is the production of ammonia gas during hydrolysis. As a possible solution, maleic acid is shown to be capable of fully promoting hydrolysis of ammonia borane...
Molecules
02:00
Molecules, Vol. 24, Pages 4043: Synergistic/Antagonistic Potential of Natural Preparations Based on Essential Oils Against Streptococcus mutans from the Oral Cavity
Molecules, Vol. 24, Pages 4043: Synergistic/Antagonistic Potential of Natural Preparations Based on Essential Oils Against Streptococcus mutans from the Oral Cavity Molecules doi: 10.3390/molecules24224043 Authors: Vlad Tiberiu Alexa Atena Galuscan Iuliana Popescu Emil Tirziu Diana Obistioiu Alin Daniel Floare Antonis Perdiou Daniela Jumanca The present paper addresses a thematic of interest in preventive dental medicine, namely the possibility of using essential...
Molecules
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4042: 1-Carbomethoxy-β-Carboline, Derived from Portulaca oleracea L., Ameliorates LPS-Mediated Inflammatory Response Associated with MAPK Signaling and Nuclear Translocation of NF-κB
Molecules, Vol. 24, Pages 4042: 1-Carbomethoxy-β-Carboline, Derived from Portulaca oleracea L., Ameliorates LPS-Mediated Inflammatory Response Associated with MAPK Signaling and Nuclear Translocation of NF-κB Molecules doi: 10.3390/molecules24224042 Authors: Kim Park Jang Lee Park Yun Lee Rho Portulaca oleracea is as a medicinal plant known for its neuroprotective, hepatoprotective, antidiabetic, antioxidant, anticancer, antimicrobial, antiulcerogenic, and...
Molecules
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4041: Chemical Constituents from Albiziae Cortex and Their Ability to Ameliorate Steatosis and Promote Proliferation and Anti-oxidation In Vitro
Molecules, Vol. 24, Pages 4041: Chemical Constituents from Albiziae Cortex and Their Ability to Ameliorate Steatosis and Promote Proliferation and Anti-oxidation In Vitro Molecules doi: 10.3390/molecules24224041 Authors: Shi Li Cai Liu Li Ai Sun Hou Ni Qiu This study describes the chemical constituents of Albiziae Cortex and their ability to ameliorate steatosis and promote proliferation and anti-oxidation in vitro. Together, five known lignan glycosides,...
Molecules
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4037: The Contribution of Carotenoids, Phenolic Compounds, and Flavonoids to the Antioxidative Properties of Marine Microalgae Isolated from Mediterranean Morocco
Molecules, Vol. 24, Pages 4037: The Contribution of Carotenoids, Phenolic Compounds, and Flavonoids to the Antioxidative Properties of Marine Microalgae Isolated from Mediterranean Morocco Molecules doi: 10.3390/molecules24224037 Authors: Imane Haoujar Francesco Cacciola Jamal Abrini Domenica Mangraviti Daniele Giuffrida Yassine Oulad El Majdoub Ayoub Kounnoun Natalizia Miceli Maria Fernanda Taviano Luigi Mondello Francesca Rigano Nadia Skali Senhaji This...
Molecules
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4044: The Dynamics of Hole Transfer in DNA
Molecules, Vol. 24, Pages 4044: The Dynamics of Hole Transfer in DNA Molecules doi: 10.3390/molecules24224044 Authors: Andrea Peluso Tonino Caruso Alessandro Landi Amedeo Capobianco High-energy radiation and oxidizing agents can ionize DNA. One electron oxidation gives rise to a radical cation whose charge (hole) can migrate through DNA covering several hundreds of Å, eventually leading to irreversible oxidative damage and consequent disease. Understanding the thermodynamic,...
Molecules
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4040: Methyl Ether-Derivatized Sterols and Coprostanol Produced via Thermochemolysis Using Tetramethylammonium Hydroxide (TMAH)
Molecules, Vol. 24, Pages 4040: Methyl Ether-Derivatized Sterols and Coprostanol Produced via Thermochemolysis Using Tetramethylammonium Hydroxide (TMAH) Molecules doi: 10.3390/molecules24224040 Authors: Nakakuni Yamasaki Yoshitake Takehara Yamamoto Sterols are widely distributed in nature from lipids in organisms to sediments. As a conventional method, extraction and derivatization with TMS have been applied for sterol analysis, requiring a long preparation time for...
Molecules
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4039: Applied Trace Alkali Metal Elements for Semiconductor Property Modulation of Perovskite Thin Films
Molecules, Vol. 24, Pages 4039: Applied Trace Alkali Metal Elements for Semiconductor Property Modulation of Perovskite Thin Films Molecules doi: 10.3390/molecules24224039 Authors: Chuangchuang Chang Xiaoping Zou Jin Cheng Tao Ling Yujun Yao Dan Chen With the rapid consumption of energy, clean solar energy has become a key study and development subject, especially the when new renewable energy perovskite solar cells (PSCs) are involved. The doping method is a common means...
Molecules
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4038: Magnetic Solid-Phase Extraction of Pyrethroid Pesticides from Environmental Water Samples Using Deep Eutectic Solvent-type Surfactant Modified Magnetic Zeolitic Imidazolate Framework-8
Molecules, Vol. 24, Pages 4038: Magnetic Solid-Phase Extraction of Pyrethroid Pesticides from Environmental Water Samples Using Deep Eutectic Solvent-type Surfactant Modified Magnetic Zeolitic Imidazolate Framework-8 Molecules doi: 10.3390/molecules24224038 Authors: Huifang Liu Lihua Jiang Meng Lu Guangyang Liu Tengfei Li Xiaomin Xu Lingyun Li Huan Lin Jun Lv Xiaodong Huang Donghui Xu A simple, sensitive and effective magnetic solid-phase extraction (MSPE)...
Molecules
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4035: Identifying Cancer-Specific circRNA–RBP Binding Sites Based on Deep Learning
Molecules, Vol. 24, Pages 4035: Identifying Cancer-Specific circRNA–RBP Binding Sites Based on Deep Learning Molecules doi: 10.3390/molecules24224035 Authors: Zhengfeng Wang Xiujuan Lei Fang-Xiang Wu Circular RNAs (circRNAs) are extensively expressed in cells and tissues, and play crucial roles in human diseases and biological processes. Recent studies have reported that circRNAs could function as RNA binding protein (RBP) sponges, meanwhile RBPs can also be involved in back-splicing....
Molecules
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4034: Design, Synthesis and Preliminary Biological Evaluation of Benzylsulfone Coumarin Derivatives as Anti-Cancer Agents
Molecules, Vol. 24, Pages 4034: Design, Synthesis and Preliminary Biological Evaluation of Benzylsulfone Coumarin Derivatives as Anti-Cancer Agents Molecules doi: 10.3390/molecules24224034 Authors: Tao Wang Tao Peng Xiaoxue Wen Gang Wang Yunbo Sun Shuchen Liu Shouguo Zhang Lin Wang In this work, a series of benzylsulfone coumarin derivatives 5a–5o were synthesized and characterized. Kinase inhibitory activity assay indicated that most of the compounds showed...
Molecules
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4033: Alkaloids with Nitric Oxide Inhibitory Activities from the Roots of Isatis tinctoria
Molecules, Vol. 24, Pages 4033: Alkaloids with Nitric Oxide Inhibitory Activities from the Roots of Isatis tinctoria Molecules doi: 10.3390/molecules24224033 Authors: Dongdong Zhang Yanhong Shi Jingyi Li Deqing Ruan Qi Jia Weiliang Zhu Kaixian Chen Yiming Li Rui Wang As our ongoing research project on Ban Lan Gen (Isatis tinctoria roots), a total of 23 alkaloids were obtained. Compounds 1 and 2 contain an unusual C–C bond between the 2(1H)-quinolinone...
Molecules
Thu Nov 07, 2019 02:00
Molecules, Vol. 24, Pages 4032: A Novel Ruthenium(II) Polypyridyl Complex Bearing 1,8-Naphthyridine as a High Selectivity and Sensitivity Fluorescent Chemosensor for Cu2+ and Fe3+ Ions
Molecules, Vol. 24, Pages 4032: A Novel Ruthenium(II) Polypyridyl Complex Bearing 1,8-Naphthyridine as a High Selectivity and Sensitivity Fluorescent Chemosensor for Cu2+ and Fe3+ Ions Molecules doi: 10.3390/molecules24224032 Authors: Chixian He Shiwen Yu Shuye Ma Zining Liu Lifeng Yao Feixiang Cheng Pinhua Liu A novel ruthenium(II) polypyridyl complex bearing 1,8-naphthyridine was successfully designed and synthesized. This complex was fully characterized by EI-HRMS,...
Molecules
Thu Nov 07, 2019 02:00

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