IJMS, Vol. 20, Pages 5606: Distinct Subcellular Compartments of Dendritic Cells Used for Cross-Presentation International Journal of Molecular Sciences doi: 10.3390/ijms20225606 Authors: Jun Imai Mayu Otani Takahiro Sakai Dendritic cells (DCs) present exogenous protein-derived peptides on major histocompatibility complex class I molecules to prime naïve CD8+ T cells. This DC specific ability, called cross-presentation (CP), is important for the activation of cell-mediated...
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IJMS, Vol. 20, Pages 5597: Celiac Disease Monocytes Induce a Barrier Defect in Intestinal Epithelial Cells International Journal of Molecular Sciences doi: 10.3390/ijms20225597 Authors: Deborah Delbue Danielle Cardoso-Silva Federica Branchi Alice Itzlinger Marilena Letizia Britta Siegmund Michael Schumann Intestinal epithelial barrier function in celiac disease (CeD) patients is altered. However, the mechanism underlying this effect is not fully understood. The aim...
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IJMS, Vol. 20, Pages 5604: Physiological and Transcriptional Responses of Industrial Rapeseed (Brassica napus) Seedlings to Drought and Salinity Stress International Journal of Molecular Sciences doi: 10.3390/ijms20225604 Authors: Ji Wang Jiao Jiao Mengjia Zhou Zeyang Jin Yongjian Yu Mingxiang Liang Abiotic stress greatly inhibits crop growth and reduces yields. However, little is known about the transcriptomic changes that occur in the industrial oilseed crop, rapeseed...
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IJMS, Vol. 20, Pages 5602: Expression and Functional Analysis of Hepcidin from Mandarin Fish (Siniperca chuatsi) International Journal of Molecular Sciences doi: 10.3390/ijms20225602 Authors: Yawei Shen Ziwei Zhao Jinliang Zhao Xiaowu Chen Ming Cao Minglin Wu Hepcidin is a liver-derived peptide hormone that is related to iron balance and immunity in humans. However, its function in Siniperca chuatsi has not been well elucidated. In this study, we analyzed the expression...
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IJMS, Vol. 20, Pages 5603: RNA-Seq-Based Comparative Transcriptome Analysis Highlights New Features of the Heat-Stress Response in the Extremophilic Bacterium Deinococcus radiodurans International Journal of Molecular Sciences doi: 10.3390/ijms20225603 Authors: Dong Xue Wenzheng Liu Yun Chen Yingying Liu Jiahui Han Xiuxiu Geng Jiang Li Shijie Jiang Zhengfu Zhou Wei Zhang Ming Chen Min Lin Marc Ongena Jin Wang Deinococcus radiodurans is best known...
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IJMS, Vol. 20, Pages 5601: Cellular Stress-Modulating Drugs Can Potentially Be Identified by in Silico Screening with Connectivity Map (CMap) International Journal of Molecular Sciences doi: 10.3390/ijms20225601 Authors: Yurong Gao Sungwoo Kim Yun-Il Lee Jaemin Lee Accompanied by increased life span, aging-associated diseases, such as metabolic diseases and cancers, have become serious health threats. Recent studies have documented that aging-associated diseases are caused by...
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IJMS, Vol. 20, Pages 5605: The Rich World of p53 DNA Binding Targets: The Role of DNA Structure International Journal of Molecular Sciences doi: 10.3390/ijms20225605 Authors: Václav Brázda Miroslav Fojta The tumor suppressor functions of p53 and its roles in regulating the cell cycle, apoptosis, senescence, and metabolism are accomplished mainly by its interactions with DNA. p53 works as a transcription factor for a significant number of genes. Most p53 target genes contain so-called...
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IJMS, Vol. 20, Pages 5600: MicroRNA-Based Therapeutic Perspectives in Myotonic Dystrophy International Journal of Molecular Sciences doi: 10.3390/ijms20225600 Authors: Arturo López Castel Sarah Joann Overby Rubén Artero Myotonic dystrophy involves two types of chronically debilitating rare neuromuscular diseases: type 1 (DM1) and type 2 (DM2). Both share similarities in molecular cause, clinical signs, and symptoms with DM2 patients usually displaying milder phenotypes. It is well...
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IJMS, Vol. 20, Pages 5598: Diesel Exhaust Particle Exposure Compromises Alveolar Macrophage Mitochondrial Bioenergetics International Journal of Molecular Sciences doi: 10.3390/ijms20225598 Authors: Jonathan L. Gibbs Blake W. Dallon Joshua B. Lewis Chase M. Walton Juan A. Arroyo Paul R. Reynolds Benjamin T. Bikman Diesel exhaust particles (DEPs) are known pathogenic pollutants that constitute a significant quantity of air pollution. Given the ubiquitous presence of...
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IJMS, Vol. 20, Pages 5595: Tilivalline- and Tilimycin-Independent Effects of Klebsiella oxytoca on Tight Junction-Mediated Intestinal Barrier Impairment International Journal of Molecular Sciences doi: 10.3390/ijms20225595 Authors: Hering Fromm Bücker Gorkiewicz Zechner Högenauer Fromm Schulzke Troeger Abstract: Klebsiella oxytoca causes antibiotic-associated hemorrhagic colitis and diarrhea. This was attributed largely to its secreted cytotoxins tilivalline...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5596: Cytocompatibility of Titanium, Zirconia and Modified PEEK after Surface Treatment Using UV Light or Non-Thermal Plasma International Journal of Molecular Sciences doi: 10.3390/ijms20225596 Authors: Linna Guo Ralf Smeets Lan Kluwe Philip Hartjen Mike Barbeck Claudio Cacaci Martin Gosau Anders Henningsen A number of modifications have been developed in order to enhance surface cytocompatibility for prosthetic support of dental implants. Among...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5594: Lipid Related Genes Altered in NASH Connect Inflammation in Liver Pathogenesis Progression to HCC: A Canonical Pathway International Journal of Molecular Sciences doi: 10.3390/ijms20225594 Authors: Desterke Chiappini Nonalcoholic steatohepatitis (NASH) is becoming a public health problem worldwide. While the number of research studies on NASH progression rises every year, sometime their findings are controversial. To identify the most important and commonly...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5593: In Silico Study of Rett Syndrome Treatment-Related Genes, MECP2, CDKL5, and FOXG1, by Evolutionary Classification and Disordered Region Assessment International Journal of Molecular Sciences doi: 10.3390/ijms20225593 Authors: Muhamad Fahmi Gen Yasui Kaito Seki Syouichi Katayama Takako Kaneko-Kawano Tetsuya Inazu Yukihiko Kubota Masahiro Ito Rett syndrome (RTT), a neurodevelopmental disorder, is mainly caused by mutations in methyl CpG-binding...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5592: Rational Design and Synthesis of Diverse Pyrimidine Molecules Bearing Sulfonamide Moiety as Novel ERK Inhibitors International Journal of Molecular Sciences doi: 10.3390/ijms20225592 Authors: Halawa Eskandrani Elgammal Hassan Hassan Ebrahim Mehany El-Agrody Okasha Protein kinases orchestrate diverse cellular functions; however, their dysregulation is linked to metabolic dysfunctions, associated with many diseases, including...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5591: RBM20 Regulates CaV1.2 Surface Expression by Promoting Exon 9* Inclusion of CACNA1C in Neonatal Rat Cardiomyocytes International Journal of Molecular Sciences doi: 10.3390/ijms20225591 Authors: Morinaga Ito Niimi Maturana The CACNA1C gene encodes for the CaV1.2 protein, which is the pore subunit of cardiac l-type voltage-gated calcium (Ca2+) channels (l-channels). Through alternative splicing, CACNA1C encodes for various CaV1.2 isoforms with different...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5590: Novel Crizotinib–GnRH conjugates revealed the significance of lysosomal trapping in GnRH-based drug delivery systems International Journal of Molecular Sciences doi: 10.3390/ijms20225590 Authors: Murányi Varga Gyulavári Pénzes Németh Csala Pethő Csámpai Halmos Peták Vályi-Nagy Several promising anti-cancer drug–GnRH (gonadotropin-releasing hormone) conjugates have been developed in the last two decades, although...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5589: Enhanced Therapeutic Potential of the Secretome Released from Adipose-Derived Stem Cells by PGC-1α-Driven Upregulation of Mitochondrial Proliferation International Journal of Molecular Sciences doi: 10.3390/ijms20225589 Authors: Jaeim Lee Ok-Hee Kim Sang Chul Lee Kee-Hwan Kim Jin Sun Shin Ha-Eun Hong Ho Joong Choi Say-June Kim Peroxisome proliferator activated receptor λ coactivator 1α (PGC-1α) is a potent...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5588: Plant-Derived Inhibitors of AHL-Mediated Quorum Sensing in Bacteria: Modes of Action International Journal of Molecular Sciences doi: 10.3390/ijms20225588 Authors: Dmitry Deryabin Anna Galadzhieva Dianna Kosyan Galimjan Duskaev Numerous gram-negative phytopathogenic and zoopathogenic bacteria utilise acylated homoserine lactone (AHL) in communication systems, referred to as quorum sensing (QS), for induction of virulence factors and biofilm development....
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5585: Suppression of Human Platelet Activation via Integrin αIIbβ3 Outside-In Independent Signal and Reduction of the Mortality in Pulmonary Thrombosis by Auraptene International Journal of Molecular Sciences doi: 10.3390/ijms20225585 Authors: Chih-Wei Hsia Cheng-Lin Tsai Joen-Rong Sheu Wan-Jung Lu Chih-Hsuan Hsia Marappan Velusamy Thanasekaran Jayakumar Jiun-Yi Li Auraptene is the most abundant coumarin derivative from plants. The pharmacological...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5586: Comparative Proteomic and Morpho-Physiological Analyses of Maize Wild-Type Vp16 and Mutant vp16 Germinating Seed Responses to PEG-Induced Drought Stress International Journal of Molecular Sciences doi: 10.3390/ijms20225586 Authors: Songtao Liu Tinashe Zenda Anyi Dong Yatong Yang Xinyue Liu Yafei Wang Jiao Li Yongsheng Tao Huijun Duan Drought stress is a major abiotic factor compromising plant cell physiological and molecular events,...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5582: Designing Microparticle-Impregnated Polyelectrolyte Composite: The Combination of ATRP, Fast Azidation, and Click Reaction Using a Single-Catalyst, Single-Pot Strategy International Journal of Molecular Sciences doi: 10.3390/ijms20225582 Authors: Ranjit De Minhyuk Jung Hohjai Lee Polystyrene microparticles were covalently impregnated into the networks of functional polyelectrolyte chains designed via a tandem run of three reactions: (i) synthesis of water-soluble...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5584: Neutrophil Maturation and Survival Is Controlled by IFN-Dependent Regulation of NAMPT Signaling International Journal of Molecular Sciences doi: 10.3390/ijms20225584 Authors: Elena Siakaeva Ekaterina Pylaeva Ilona Spyra Sharareh Bordbari Benedikt Höing Cornelius Kürten Stephan Lang Jadwiga Jablonska Granulocyte-colony stimulating factor (G-CSF)/nicotinamide phosphoribosyltransferase (NAMPT) signaling has been shown to be crucial for the...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5577: Interspecies Outer Membrane Vesicles (OMVs) Modulate the Sensitivity of Pathogenic Bacteria and Pathogenic Yeasts to Cationic Peptides and Serum Complement International Journal of Molecular Sciences doi: 10.3390/ijms20225577 Authors: Justyna Roszkowiak Paweł Jajor Grzegorz Guła Jerzy Gubernator Andrzej Żak Zuzanna Drulis-Kawa Daria Augustyniak The virulence of bacterial outer membrane vesicles (OMVs) contributes to innate microbial defense....
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5587: Transgenerational Response to Nitrogen Deprivation in Arabidopsis thaliana International Journal of Molecular Sciences doi: 10.3390/ijms20225587 Authors: Monica Massaro Emanuele De Paoli Nicola Tomasi Michele Morgante Roberto Pinton Laura Zanin Nitrogen (N) deficiency is one of the major stresses that crops are exposed to. It is plausible to suppose that a stress condition can induce a memory in plants that might prime the following generations....
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5581: N-Dihydrogalactochitosan Potentiates the Radiosensitivity of Liver Metastatic Tumor Cells Originated from Murine Breast Tumors International Journal of Molecular Sciences doi: 10.3390/ijms20225581 Authors: Chung-Yih Wang Chun-Yuan Chang Chun-Yu Wang Kaili Liu Chia-Yun Kang Yi-Jang Lee Wei R. Chen Radiation is a widely used therapeutic method for treating breast cancer. N-dihydrogalactochitosan (GC), a biocompatible immunostimulant, is known...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5583: Computational Nanoscopy of Tight Junctions at the Blood–Brain Barrier Interface International Journal of Molecular Sciences doi: 10.3390/ijms20225583 Authors: Nandhini Rajagopal Flaviyan Jerome Irudayanathan Shikha Nangia The selectivity of the blood–brain barrier (BBB) is primarily maintained by tight junctions (TJs), which act as gatekeepers of the paracellular space by blocking blood-borne toxins, drugs, and pathogens from entering the brain....
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5579: Combination Radioimmunotherapy Strategies for Solid Tumors International Journal of Molecular Sciences doi: 10.3390/ijms20225579 Authors: Javeria Zaheer Hyeongi Kim Yong-Jin Lee Jin Su Kim Sang Moo Lim Combination radioimmunotherapy is an emerging approach for the treatment of solid tumors where radio immunotherapy alone has proven to be reasonably ineffective. Radioimmunotherapy (RIT) using monoclonal antibodies (mAbs) labeled with radionuclides...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5578: The Role of Electron Transfer in the Fragmentation of Phenyl and Cyclohexyl Boronic Acids International Journal of Molecular Sciences doi: 10.3390/ijms20225578 Authors: Ana Isabel Lozano Beatriz Pamplona Tymon Kilich Marta Łabuda Mónica Mendes João Pereira-da-Silva Gustavo García Pedro M. P. Góis Filipe Ferreira da Silva Paulo Limão-Vieira In this study, novel measurements of negative ion formation in neutral potassium-neutral boronic...
Fri Nov 08, 2019 02:00
IJMS, Vol. 20, Pages 5580: Food Allergies and Ageing International Journal of Molecular Sciences doi: 10.3390/ijms20225580 Authors: Massimo De Martinis Maria Maddalena Sirufo Angelo Viscido Lia Ginaldi All over the world, there is an increase in the overall survival of the population and the number of elderly people. The incidence of allergic reactions is also rising worldwide. Until recently, allergies, and in particular food allergies (FAs), was regarded as a pediatric problem,...
Fri Nov 08, 2019 02:00
JCDD, Vol. 6, Pages 40: Spontaneous Left Cardiac Isomerism in Chick Embryos: Case Report, Review of the Literature, and Possible Significance for the Understanding of Ventricular Non-Compaction Cardiomyopathy in the Setting of Human Heterotaxy Syndromes Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd6040040 Authors: Jörg Männer The outer shape of most vertebrates is normally characterized by bilateral symmetry. The inner organs, on the other hand, are normally arranged...
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1925: Bevacizumab Induces Upregulation of Keratin 3 and VEGFA in Human Limbal Epithelial Cells in Vitro Journal of Clinical Medicine doi: 10.3390/jcm8111925 Authors: Maria Notara Anna Lentzsch Thomas Clahsen Sara Behboudifard Gabriele Braun Claus Cursiefen Topical application of vascular endothelial growth factor A (VEGFA) inhibitors including Bevacizumab is used for antiangiogenic therapy at the ocular surface. While clinical studies have suggested...
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JCM, Vol. 8, Pages 1924: Perinatal Outcome and Long-Term Gastrointestinal Morbidity of Offspring of Women with Celiac Disease Journal of Clinical Medicine doi: 10.3390/jcm8111924 Authors: Abecassis Wainstock Sheiner Pariente The aim of this study was to evaluate perinatal outcome and long-term offspring gastrointestinal morbidity of women with celiac disease. Perinatal outcomes, as well as long-term gastrointestinal morbidity of offspring of mothers with and without celiac...
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1922: Are We Sure that Adjuvant Chemotherapy is the Best Approach for Resectable Pancreatic Cancer? Are We in the Era of Neoadjuvant Treatment? A Review of Current Literature Journal of Clinical Medicine doi: 10.3390/jcm8111922 Authors: Oneda Zaniboni The outcome of pancreatic cancer is poor, with a 9% 5-year survival rate. Current treatment recommendations in the 10%–20% of patients who present with resectable disease support upfront resection followed...
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1923: Management of Dehydration in Patients Suffering Swallowing Difficulties Journal of Clinical Medicine doi: 10.3390/jcm8111923 Authors: Reber Gomes Dähn Vasiloglou Stanga Swallowing difficulties, also called dysphagia, can have various causes and may occur at many points in the swallowing process. The treatment and rehabilitation of dysphagia represent a major interdisciplinary and multiprofessional challenge. In dysphagic patients, dehydration...
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1919: Impact of a Prescription Support Tool to Improve Adherence to the Guidelines for the Prescription of Oral Antithrombotics: The Combi-AT Randomized Controlled Trial Using Clinical Vignettes Journal of Clinical Medicine doi: 10.3390/jcm8111919 Authors: Zerah Bonnet-Zamponi Dechartres Frappé Hauguel-Moreau Collet Rycke Tubach Ensuring the appropriateness of prescriptions of oral antithrombotics (ATs, including antiplatelet and anticoagulant...
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1920: Real-World Experience of Olaparib Maintenance in High-Grade Serous Recurrent Ovarian Cancer Patients with BRCA1/2 Mutation: A Korean Multicenter Study Journal of Clinical Medicine doi: 10.3390/jcm8111920 Authors: Paik Lee Lee Shin Park Kim Kim Choi Kim Background: Olaparib maintenance therapy has shown efficacy and tolerability in patients with platinum-sensitive, high-grade serous recurrent ovarian cancer (HSROC) with BRCA1/2...
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1921: Post-Concussion Symptoms in Complicated vs. Uncomplicated Mild Traumatic Brain Injury Patients at Three and Six Months Post-Injury: Results from the CENTER-TBI Study Journal of Clinical Medicine doi: 10.3390/jcm8111921 Authors: Daphne C. Voormolen Juanita A. Haagsma Suzanne Polinder Andrew I.R. Maas Ewout W. Steyerberg Petar Vuleković Charlie A. Sewalt Benjamin Y. Gravesteijn Amra Covic Nada Andelic Anne Marie Plass Nicole von Steinbuechel...
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1915: Anorexia Nervosa and the Immune System—A Narrative Review Journal of Clinical Medicine doi: 10.3390/jcm8111915 Authors: Dennis Gibson Philip S Mehler The pathogenesis of an increasing number of chronic diseases is being attributed to effects of the immune system. However, its role in the development and maintenance of anorexia nervosa is seemingly under-appreciated. Yet, in examining the available research on the immune system and genetic studies in anorexia...
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1918: Human Red Blood Cells as Oxygen Carriers to Improve Ex-Situ Liver Perfusion in a Rat Model Journal of Clinical Medicine doi: 10.3390/jcm8111918 Authors: Daniele Dondossola Alessandro Santini Caterina Lonati Alberto Zanella Riccardo Merighi Luigi Vivona Michele Battistin Alessandro Galli Osvaldo Biancolilli Marco Maggioni Stefania Villa Stefano Gatti Ex-situ machine perfusion (MP) has been increasingly used to enhance liver quality...
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1917: Visualization of Accessory Lymphatic Pathways, before and after Manual Drainage, in Secondary Upper Limb Lymphedema Using Indocyanine Green Lymphography Journal of Clinical Medicine doi: 10.3390/jcm8111917 Authors: María Elena Medina-Rodríguez María de-la-Casa-Almeida Efrén Martel-Almeida Arminda Ojeda-Cárdenes Esther M. Medrano-Sánchez Manual Lymphatic Drainage (MLD) appears to stimulate lymphatic contraction, aid in the development of secondary...
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1914: Fruit and Vegetable Concentrate Supplementation and Cardiovascular Health: A Systematic Review from a Public Health Perspective Journal of Clinical Medicine doi: 10.3390/jcm8111914 Authors: Giulia Lorenzoni Clara Minto Maria Gabriella Vecchio Slavica Zec Irene Paolin Manfred Lamprecht Luisa Mestroni Dario Gregori Fruits and vegetables (FV) are very important for the prevention of noncommunicable diseases (NCDs), but it has been demonstrated...
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1916: Correlations between Molecular Landscape and Sonographic Image of Different Variants of Papillary Thyroid Carcinoma Journal of Clinical Medicine doi: 10.3390/jcm8111916 Authors: Andrzej Lewiński Zbigniew Adamczewski Arkadiusz Zygmunt Leszek Markuszewski Małgorzata Karbownik-Lewińska Magdalena Stasiak Papillary thyroid carcinoma (PTC), the most common thyroid cancer, is predominantly driven by mutations in BRAF (primarily p. V600E) and RAS oncogenes....
Fri Nov 08, 2019 02:00
JCM, Vol. 8, Pages 1913: The Impact of Neighbourhood Deprivation on Embryonic Growth Trajectories: Rotterdam Periconception Cohort Journal of Clinical Medicine doi: 10.3390/jcm8111913 Authors: Dionne V. Gootjes Maria P. H. Koster Sten P. Willemsen Anton H. J. Koning Eric A. P. Steegers Régine P. M. Steegers-Theunissen Background: Neighbourhood deprivation is a risk factor for impaired health and adverse pregnancy outcomes. We investigated whether living in a deprived neighbourhood...
Fri Nov 08, 2019 02:00
Medicina, Vol. 55, Pages 730: Factors Associated With Low Lean Mass in Early Rheumatoid Arthritis: A Cross- Sectional Study Medicina doi: 10.3390/medicina55110730 Authors: Müller Kull Põlluste Valner Lember Kallikorm Background and Objectives: The aim of the study was to evaluate body composition (BC) of rheumatoid arthritis (RA) patients at disease onset compared to population controls focusing on the associations between low lean mass and disease specific parameters,...
Fri Nov 08, 2019 02:00
Membranes, Vol. 9, Pages 147: Nanofiltration of Succinic Acid in Strong Alkaline Conditions Membranes doi: 10.3390/membranes9110147 Authors: Schlackl Herchl Samhaber Nanofiltration is considered to be an appropriate separation technique in the production of bio-based materials. For the utilization of process streams from the viscose-fiber production, understanding the separation behavior of organic compounds in highly alkaline solutions is necessary. Experiments with succinic...
Fri Nov 08, 2019 02:00
Metabolites, Vol. 9, Pages 272: A New Perspective on the Health Benefits of Moderate Beer Consumption: Involvement of the Gut Microbiota Metabolites doi: 10.3390/metabo9110272 Authors: Mar Quesada-Molina Araceli Muñoz-Garach Francisco J. Tinahones Isabel Moreno-Indias Beer is the most widely consumed fermented beverage in the world. A moderate consumption of beer has been related to important healthy outcomes, although the mechanisms have not been fully understood. Beer contains...
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Microorganisms, Vol. 7, Pages 544: Bifidobacterium bifidum: A Key Member of the Early Human Gut Microbiota Microorganisms doi: 10.3390/microorganisms7110544 Authors: Francesca Turroni Sabrina Duranti Christian Milani Gabriele Andrea Lugli Douwe van Sinderen Marco Ventura Bifidobacteria typically represent the most abundant bacteria of the human gut microbiota in healthy breast-fed infants. Members of the Bifidobacterium bifidum species constitute one of the dominant taxa...
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Microorganisms, Vol. 7, Pages 543: The Effect of Nitrogen Content on Archaeal Diversity in an Arctic Lake Region Microorganisms doi: 10.3390/microorganisms7110543 Authors: Lv Liu Han Wang Zhu Zang Wang Zhang Wang The function of Arctic soil ecosystems is crucially important for the global climate, and nitrogen (N) is the major limiting nutrient in these environments. This study assessed the effects of changes in nitrogen content on archaeal community...
Fri Nov 08, 2019 02:00
Microorganisms, Vol. 7, Pages 541: Isolation, Screening, and Characterization of Plant-Growth-Promoting Bacteria from Durum Wheat Rhizosphere to Improve N and P Nutrient Use Efficiency Microorganisms doi: 10.3390/microorganisms7110541 Authors: Nilde Antonella Di Benedetto Daniela Campaniello Antonio Bevilacqua Mariagrazia Pia Cataldi Milena Sinigaglia Zina Flagella Maria Rosaria Corbo The main goal of this paper was to select promising microorganisms which could potentially...
Fri Nov 08, 2019 02:00
Microorganisms, Vol. 7, Pages 542: First Proteomic Approach to Identify Cell Death Biomarkers in Wine Yeasts during Sparkling Wine Production Microorganisms doi: 10.3390/microorganisms7110542 Authors: Porras-Agüera Moreno-García Mauricio Moreno García-Martínez Apoptosis and later autolysis are biological processes which take place in Saccharomyces cerevisiae during industrial fermentation processes, which involve costly and time-consuming aging periods. Therefore, the...
Fri Nov 08, 2019 02:00
Microorganisms, Vol. 7, Pages 540: Comparison of Six Commercial Meat Starter Cultures for the Fermentation of Yellow Mealworm (Tenebrio molitor) Paste Microorganisms doi: 10.3390/microorganisms7110540 Authors: Borremans An Crauwels Sam Vandeweyer Dries Smets Ruben Verreth Christel Van Der Borght Mik Lievens Bart Van Campenhout Leen Huanglongbing (HLB), also known as citrus greening, is the most destructive disease of citrus worldwide. HLB is associated with the non-culturable...
Fri Nov 08, 2019 02:00
Microorganisms, Vol. 7, Pages 539: Requirement of lmo1930, a Gene in the Menaquinone Biosynthesis Operon, for Esculin Hydrolysis and Lithium Chloride Tolerance in Listeria monocytogenes Microorganisms doi: 10.3390/microorganisms7110539 Authors: Cameron Parsons Midya Jahanafroozi Sophia Kathariou Listeria monocytogenes is a foodborne pathogen that is widely distributed in nature, having been isolated from a variety of sources such as soil, water, plant matter, and animals. In addition,...
Fri Nov 08, 2019 02:00
Molecules, Vol. 24, Pages 4053: Antimicrobial Effect of Picea abies Extracts on E. coli Growth Molecules doi: 10.3390/molecules24224053 Authors: Nabil Haman Ksenia Morozova Giustino Tonon Matteo Scampicchio Giovanna Ferrentino This study aims to investigate the effect of essential oils extracted from wood residues of Picea abies on the growth of Escherichia coli. The essential oils were extracted by supercritical carbon dioxide, leading to a yield of 3.4 ± 0.5%...
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Molecules, Vol. 24, Pages 4057: Catalytic Hydrolysis Mechanism of Cocaine by Human Carboxylesterase 1: An Orthoester Intermediate Slows Down the Reaction Molecules doi: 10.3390/molecules24224057 Authors: Maocai Yan Zhen Zhang Zhaoming Liu Chunyan Zhang Jingchang Zhang Shuai Fan Zhaoyong Yang Human carboxylesterase 1 (hCES1) is a major carboxylesterase in the human body and plays important roles in the metabolism of a wide variety of substances, including lipids and...
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Molecules, Vol. 24, Pages 4056: Cell Suspensions of Cannabis sativa (var. Futura): Effect of Elicitation on Metabolite Content and Antioxidant Activity Molecules doi: 10.3390/molecules24224056 Authors: Damiano Gabotti Franca Locatelli Erica Cusano Elena Baldoni Annamaria Genga Laura Pucci Roberto Consonni Monica Mattana Cannabis sativa L. is one of the most-studied species for its phytochemistry due to the abundance of secondary metabolites, including cannabinoids,...
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Molecules, Vol. 24, Pages 4055: Retrochalcone Echinatin Triggers Apoptosis of Esophageal Squamous Cell Carcinoma via ROS- and ER Stress-Mediated Signaling Pathways Molecules doi: 10.3390/molecules24224055 Authors: Ah-Won Kwak Joon-Seok Choi Mee-Hyun Lee Ha-Na Oh Seung-Sik Cho Goo Yoon Kangdong Liu Jung-Il Chae Jung-Hyun Shim Esophageal squamous cell carcinoma (ESCC) is a poor prognostic cancer with a low five-year survival rate. Echinatin (Ech) is a retrochalone...
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Molecules, Vol. 24, Pages 4058: Organocatalytic Asymmetric Conjugate Addition of Aldehydes to Maleimides and Nitroalkenes in Deep Eutectic Solvents Molecules doi: 10.3390/molecules24224058 Authors: Alejandro Torregrosa-Chinillach Alba Sánchez-Laó Elisa Santagostino Rafael Chinchilla A chiral primary amine-salicylamide is used as an organocatalyst for the enantioselective conjugate addition of α,α-disubstituted aldehydes to maleimides and nitroalkenes. The...
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Molecules, Vol. 24, Pages 4054: Encapsulation of Upconversion Nanoparticles in Periodic Mesoporous Organosilicas Molecules doi: 10.3390/molecules24224054 Authors: Saher Rahmani Chiara Mauriello Jimenez Dina Aggad Daniel González-Mancebo Manuel Ocaña Lamiaa M. A. Ali Christophe Nguyen Ana Isabel Becerro Nieto Nadège Francolon Erwan Oliveiro Damien Boyer Rachid Mahiou Laurence Raehm Magali Gary-Bobo Jean-Olivier Durand Clarence Charnay (1) Background:...
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Molecules, Vol. 24, Pages 4052: A Simple, Efficient, and Eco-Friendly Method for the Preparation of 3-Substituted-2,3-dihydroquinazolin-4(1H)-one Derivatives Molecules doi: 10.3390/molecules24224052 Authors: Zainab Almarhoon Kholood A. Dahlous Rakia Abd Alhameed Hazem A. Ghabbour Ayman El-Faham A simple, cost-effective method under environmentally benign conditions is a very important concept for the preparation of 2,3-dihydroquinazolin-4(1H)-one derivatives. The present...
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Molecules, Vol. 24, Pages 4051: New Hydroxydecanoic Acid Derivatives Produced by an Dndophytic Yeast Aureobasidium pullulans AJF1 from Flowers of Aconitum carmichaeli Molecules doi: 10.3390/molecules24224051 Authors: Choi Kim Choi Kang Shim Endophytes have been recognized as a source for structurally novel and biologically active secondary metabolites. Among the host plants for endophytes, some medicinal plants that produce pharmaceuticals have been reported to carry...
Fri Nov 08, 2019 02:00
Molecules, Vol. 24, Pages 4050: Study on Hypoglycemic Effect of the Drug Pair of Astragalus Radix and Dioscoreae Rhizoma in T2DM Rats by Network Pharmacology and Metabonomics Molecules doi: 10.3390/molecules24224050 Authors: Guo Niu Li Guo Zhang Wang Wu Type 2 diabetes mellitus (T2DM) is a metabolic disease accompanied by a series of diseases such as diabetic nephropathy. The drug pair (HS) of Astragalus Radix (HQ) and Dioscoreae Rhizoma (SY) was designed by...
Fri Nov 08, 2019 02:00
Molecules, Vol. 24, Pages 4049: Spruce Bark—A Source of Polyphenolic Compounds: Optimizing the Operating Conditions of Supercritical Carbon Dioxide Extraction Molecules doi: 10.3390/molecules24224049 Authors: Petra Strižincová Aleš Ház Zuzana Burčová Jozef Feranc František Kreps Igor Šurina Michal Jablonský The present study described the optimization of the extraction process with carbon dioxide in supercritical state for obtaining extractives, especially polyphenols...
Fri Nov 08, 2019 02:00
Molecules, Vol. 24, Pages 4048: Microwave-Assisted Green Synthesis and Antioxidant Activity of Selenium Nanoparticles Using Theobroma Cacao L. Bean Shell Extract Molecules doi: 10.3390/molecules24224048 Authors: Mellinas Jiménez Garrigós Selenium nanoparticles (SeNPs) are successfully synthesized through microwave heating by using Theobroma cacao L. bean shell extract as a stabilizing and capping agent. Response surface methodology is used to obtain optimal synthesis conditions....
Fri Nov 08, 2019 02:00
Molecules, Vol. 24, Pages 4047: Essential Oil Composition of Ruta graveolens L. Fruits and Hyssopus officinalis Subsp. aristatus (Godr.) Nyman Biomass as a Function of Hydrodistillation Time Molecules doi: 10.3390/molecules24224047 Authors: Ivanka B. Semerdjieva Marian Burducea Tess Astatkie Valtcho D. Zheljazkov Ivayla Dincheva The aim of this study was to establish the kinetics regression models for yield and composition of Ruta graveolens fruit and Hyssopus officinalis...
Fri Nov 08, 2019 02:00
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