Microvascular Effects of Pulsed Dye Laser in Combination With Oxymetazoline

Background and Objective Oxymetazoline, an α‐1A agonist, is approved by the United States Food and Drug Administration (FDA) for treatment of persistent facial erythema associated with rosacea and induces vasoconstriction by interacting with α receptors. The objective of our study was to study the microvascular effects of oxymetazoline and pulsed dye laser (PDL). Materials and Methods A dorsal window chamber was surgically installed on 20 mice. Each animal was assigned to one of four experimental...

Lasers in Surgery and Medicine

Fri Nov 22, 2019 19:20

Analysis of Impact of Humidity and Temperature on Excimer Laser Ablation of Polyethylene Terephthalate, Polymethylmethacrylate, and Porcine Corneal Tissue

Background and Objectives To analyze the impact of humidity and temperature on excimer laser ablation of polyethylene terephthalate (PET), polymethylmethacrylate (PMMA) and porcine corneal tissue, and an ablation model to compensate for the temperature and humidity changes on ablation efficiency. Study Design/Materials and Methods The study was conducted using an AMARIS 1050RS (Schwind eye‐tech‐solutions) placed inside a climate chamber at ACTS. Ablations were performed on PET, PMMA, and porcine...

Lasers in Surgery and Medicine

Fri Nov 22, 2019 19:18

Capillary Refill—The Key to Assessing Dermal Capillary Capacity and Pathology in Optical Coherence Tomography Angiography

Background/Objectives Standard optical coherence tomography angiography (OCTA) has been limited to imaging blood vessels actively undergoing perfusion, providing a temporary picture of surface microvasculature. Capillary perfusion in the skin is dynamic and changes in response to the surrounding tissue's respiratory, nutritional, and thermoregulatory needs. Hence, OCTA often represents a given perfusion state without depicting the actual extent of the vascular network. Here we present a method for...

Lasers in Surgery and Medicine

Thu Nov 21, 2019 19:05