Molecules, Vol. 24, Pages 4263: Bioactive Plant Compounds in Coffee Charcoal (Coffeae carbo) Extract Inhibit Cytokine Release from Activated Human THP-1 Macrophages Molecules doi: 10.3390/molecules24234263 Authors: Weber Hammoud Mahdi Jankuhn Lipowicz Vissiennon The herbal preparation coffee charcoal is produced by over-roasting and milling green dried Coffea arabica L. seeds, and has a long-standing tradition in the treatment of inflammatory and gastrointestinal disorders....
Fri Nov 22, 2019 02:00
Molecules, Vol. 24, Pages 4265: Semi-Synthetic Ingenol Derivative from Euphorbia tirucalli Inhibits Protein Kinase C Isotypes and Promotes Autophagy and S-phase Arrest on Glioma Cell Lines Molecules doi: 10.3390/molecules24234265 Authors: Silva Rosa Tansini Martinho Tanuri Evangelista Cruvinel Carloni Lima Pianowski Reis The identification of signaling pathways that are involved in gliomagenesis is crucial for targeted therapy design. In this study...
Fri Nov 22, 2019 02:00
Molecules, Vol. 24, Pages 4262: Effects of l-Carnitine in Patients with Autism Spectrum Disorders: Review of Clinical Studies Molecules doi: 10.3390/molecules24234262 Authors: Michele Malaguarnera Omar Cauli Carnitine is an amino acid derivative, which plays several important roles in human physiology, in the central nervous system, and for mitochondrial metabolism, in particular. Altered carnitine metabolic routes have been associated with a subgroup of patients with autism spectrum...
Fri Nov 22, 2019 02:00
Molecules, Vol. 24, Pages 4256: Evidence for Effective Inhibitory Actions on Hyperpolarization-Activated Cation Current Caused by Ganoderma Triterpenoids, the Main Active Constitutents of Ganoderma Spores Molecules doi: 10.3390/molecules24234256 Authors: Wei-Ting Chang Zi-Han Gao Yi-Ching Lo Sheng-Nan Wu The triterpenoid fraction of Ganoderma (Ganoderma triterpenoids, GTs) has been increasingly demonstrated to provide effective antioxidant, neuroprotective or cardioprotective...
Fri Nov 22, 2019 02:00
Molecules, Vol. 24, Pages 4260: Effects of Ultrasonic-Assisted Extraction on the Physicochemical Properties of Different Walnut Proteins Molecules doi: 10.3390/molecules24234260 Authors: Siyi Lv Ahmed Taha Hao Hu Qi Lu Siyi Pan The effects of ultrasonic-assisted extraction (UAE, 200 W, 20 min) on the yield and physicochemical properties of different walnut proteins (WNPs, including albumin, globulin, and glutelin) were investigated. Sodium dodecyl sulfate polyacrylamide gel...
Fri Nov 22, 2019 02:00
Molecules, Vol. 24, Pages 4261: Solid-Phase Insertion of N-mercaptoalkylglycine Residues into Peptides Molecules doi: 10.3390/molecules24234261 Authors: Spyridon Mourtas Dimitrios Gatos Kleomenis Barlos N-mercaptoalkylglycine residues were inserted into peptides by reacting N-free amino groups of peptides, which were initially synthesized on 2-chlorotrityl resin (Cltr) using the Fmoc/tBu method, with bromoacetic acid and subsequent nucleophilic replacement of the bromide by reacting...
Fri Nov 22, 2019 02:00
Molecules, Vol. 24, Pages 4258: Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking and Biological Evaluation for Identification of Potential Poly (ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors Molecules doi: 10.3390/molecules24234258 Authors: Yunjiang Zhou Shi Tang Tingting Chen Miao-Miao Niu Poly (ADP-ribose) polymerase-1 (PARP-1) plays critical roles in many biological processes and is considered as a potential target for anticancer therapy. Although...
Fri Nov 22, 2019 02:00
Molecules, Vol. 24, Pages 4257: Isolation of a Halogen-Bonded Complex Formed between Methane and Chlorine Monofluoride and Characterisation by Rotational Spectroscopy and Ab Initio Calculations Molecules doi: 10.3390/molecules24234257 Authors: Anthony C. Legon David G. Lister John H. Holloway Devendra Mani Elangannan Arunan A halogen-bonded complex formed between methane and chlorine monofluoride has been isolated in the gas phase before the reaction between the components...
Fri Nov 22, 2019 02:00
Molecules, Vol. 24, Pages 4259: Natural Bioactive Compounds As Protectors Of Mitochondrial Dysfunction In Cardiovascular Diseases And Aging Molecules doi: 10.3390/molecules24234259 Authors: Diego Arauna María Furrianca Yolanda Espinosa-Parrilla Eduardo Fuentes Marcelo Alarcón Iván Palomo Diet, particularly the Mediterranean diet, has been considered as a protective factor against the development of cardiovascular diseases, the main cause of death in the world. Aging is...
Fri Nov 22, 2019 02:00
Molecules, Vol. 24, Pages 4254: The Effects of Different Varieties of Aurantii Fructus Immaturus on the Potential Toxicity of Zhi-Zi-Hou-Po Decoction Based on Spectrum-Toxicity Correlation Analysis Molecules doi: 10.3390/molecules24234254 Authors: Qianqian Zhang Fang Feng In accordance with the provision in China Pharmacopoeia, Citrus aurantium L. (Sour orange—SZS) and Citrus sinensis Osbeck (Sweet orange—TZS) are all in line with the requirements of Aurantii Fructus...
Fri Nov 22, 2019 02:00
Molecules, Vol. 24, Pages 4255: Anthocyanins Potentially Contribute to Defense against Alzheimer’s Disease Molecules doi: 10.3390/molecules24234255 Authors: Mohammad Afzal Amina Redha Redha AlHasan Anthocyanins (ANTs) are plant pigments that belong to a flavanol class of polyphenols and have diverse pharmacological properties. These compounds are primarily found in fruits and vegetables, with an average daily intake of 180 mgd−1 of these compounds in the developed world....
Fri Nov 22, 2019 02:00
Molecules, Vol. 24, Pages 4253: Glutathione Deficiency and Alterations in the Sulfur Amino Acid Homeostasis during Early Postnatal Development as Potential Triggering Factors for Schizophrenia-Like Behavior in Adult Rats Molecules doi: 10.3390/molecules24234253 Authors: Magdalena Górny Agnieszka Wnuk Adrianna Kamińska Kinga Kamińska Grażyna Chwatko Anna Bilska-Wilkosz Małgorzata Iciek Małgorzata Kajta Zofia Rogóż Elżbieta Lorenc-Koci Impaired glutathione (GSH)...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1671: Photocatalytic Performance of SiO2/CNOs/TiO2 to Accelerate the Degradation of Rhodamine B under Visible Light Nanomaterials doi: 10.3390/nano9121671 Authors: Zhang Zhang Yang Yang Jia Guo A silicon dioxide/carbon nano onions/titanium dioxide (SiO2/CNOs/TiO2) composite was synthesized by a simple sol-gel method and characterized by the methods of X-ray diffraction (XRD), scanning electronic microscope (SEM), X-ray photoelectron spectroscopy...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1670: Comparative Molecular Immunological Activity of Physiological Metal Oxide Nanoparticle and its Anticancer Peptide and RNA Complexes Nanomaterials doi: 10.3390/nano9121670 Authors: Robert K. DeLong Jeffrey Comer Elza Neelima Mathew Majid Jaberi-Douraki Currently, there is a great interest in nanoparticle-based vaccine delivery. Recent studies suggest that nanoparticles when introduced into the biological milieu are not simply passive carriers...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1669: Inhibitory Effects of Cu2O/SiO2 on the Growth of Microcystis aeruginosa and Its Mechanism Nanomaterials doi: 10.3390/nano9121669 Authors: Gongduan Fan Minchen Bao Bo Wang Shimin Wu Lingxi Luo Binhui Li Jiuhong Lin In this study, a novel nanomaterial Cu2O/SiO2 was synthesized based on nano-SiO2, and the inhibitory effects of different concentrations of Cu2O/SiO2 on the growth of Microcystis aeruginosa (M. aeruginosa) were studied. At...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1672: Self-Propelled Janus Microdimer Swimmers under a Rotating Magnetic Field Nanomaterials doi: 10.3390/nano9121672 Authors: Shimin Yu Ningze Ma Hao Yu Haoran Sun Xiaocong Chang Zhiguang Wu Jiaxuan Deng Shuqi Zhao Wuyi Wang Guangyu Zhang Weiwei Zhang Qingsong Zhao Tianlong Li Recent strides in micro- and nanofabrication technology have enabled researchers to design and develop new micro- and nanorobots for biomedicine...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1668: Bacterial Nanocellulose and Its Surface Modification by Glycidyl Methacrylate and Ethylene Glycol Dimethacrylate. Incorporation of Vancomycin and Ciprofloxacin Nanomaterials doi: 10.3390/nano9121668 Authors: Vismara Bernardi Bongio Farè Pappalardo Serafini Pollegioni Rosini Torri Among nanocelluloses, bacterial nanocellulose (BNC) has proven to be a promising candidate in a range of biomedical applications, from topical...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1665: Natural Antibacterial Reagents (Centella, Propolis, and Hinokitiol) Loaded into Poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate] Composite Nanofibers for Biomedical Applications Nanomaterials doi: 10.3390/nano9121665 Authors: Rina Afiani Rebia Nurul Shaheera binti Sadon Toshihisa Tanaka Centella asiatica, propolis, and hinokitiol, as natural antibacterial reagents, were integrated into the poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate]...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1666: All-Inorganic Perovskite Solar Cells Based on CsPbIBr2 and Metal Oxide Transport Layers with Improved Stability Nanomaterials doi: 10.3390/nano9121666 Authors: Jien Yang Qiong Zhang Jinjin Xu Hairui Liu Ruiping Qin Haifa Zhai Songhua Chen Mingjian Yuan Despite the successful improvement in the power conversion efficiency (PCE) of perovskite solar cells (PSCs), the issue of instability is still a serious challenge for their commercial...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1663: Nanomaterials towards Biosensing of Alzheimer’s Disease Biomarkers Nanomaterials doi: 10.3390/nano9121663 Authors: Pedro Carneiro Simone Morais Maria Carmo Pereira Alzheimer’s disease (AD) is an incurable and highly debilitating condition characterized by the progressive degeneration and/or death of nerve cells, which leads to manifestation of disabilities in cognitive functioning. In recent years, the development of biosensors for determination...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1667: Fabrication of BaTiO3-Loaded Graphene Nanosheets-Based Polyarylene Ether Nitrile Nanocomposites with Enhanced Dielectric and Crystallization Properties Nanomaterials doi: 10.3390/nano9121667 Authors: Shuning Liu Chenchen Liu Yong You Yajie Wang Renbo Wei Xiaobo Liu In this paper, barium titanate@zinc phthalocyanine (BT@ZnPc) and graphene oxide (GO) hybrids (BT@ZnPc-GO) connected by calcium ions are prepared by electrostatic adsorption,...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1664: Studies on Possible Ion-Confinement in Nanopore for Enhanced Supercapacitor Performance in 4V EMIBF4 Ionic Liquids Nanomaterials doi: 10.3390/nano9121664 Authors: Jie Deng Jing Li Zhe Xiao Shuang Song Luming Li Supercapacitors have the rapid charge/discharge kinetics and long stability in comparison with various batteries yet undergo low energy density. Theoretically, square dependence of energy density upon voltage reveals a fruitful but...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1661: Oriented Cell Alignment Induced by a Nanostructured Titanium Surface Enhances Expression of Cell Differentiation Markers Nanomaterials doi: 10.3390/nano9121661 Authors: Maria Antonia Llopis-Grimalt Andreu Miquel Amengual-Tugores Marta Monjo Joana Maria Ramis A key factor for dental implant success is a good sealing between the implant surface and both soft (gum) and hard (bone) tissues. Surface nanotopography can modulate cell response through...
Fri Nov 22, 2019 02:00
Nanomaterials, Vol. 9, Pages 1662: External Field-Controlled Ablation: Magnetic Field Nanomaterials doi: 10.3390/nano9121662 Authors: Jovan Maksimovic Soon Hock Ng Tomas Katkus Bruce C. C. Cowie Saulius Juodkazis The femtosecond laser ablation of silicon amidst an externally applied magnetic field in different orientations was investigated with respect to the scanning direction and polarisation of the laser beam, by observation of ablation patterns and debris displacement...
Fri Nov 22, 2019 02:00
Nutrients, Vol. 11, Pages 2869: Fragmented Dosing of β-alanine Induces A Body Weight-Independent Pharmacokinetic Response Nutrients doi: 10.3390/nu11122869 Authors: Jan Stautemas Alexia Van de Loock Thibaux Van der Stede Lauren Pringels Wim Derave Personalised dosing of performance-enhancing food supplements is a hot topic. β-alanine is currently dosed using a fixed dose; however, evidence suggests that this might favour light compared to heavy subjects. A weight-relative...
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Nutrients, Vol. 11, Pages 2868: Dietary Omega-3 Fatty Acid Dampens Allergic Rhinitis via Eosinophilic Production of the Anti-Allergic Lipid Mediator 15-Hydroxyeicosapentaenoic Acid in Mice Nutrients doi: 10.3390/nu11122868 Authors: Kento Sawane Takahiro Nagatake Koji Hosomi So-ichiro Hirata Jun Adachi Yuichi Abe Junko Isoyama Hidehiko Suzuki Ayu Matsunaga Satoshi Fukumitsu Kazuhiko Aida Takeshi Tomonaga Makoto Aria Jun Kunisawa The metabolism and...
Fri Nov 22, 2019 02:00
Nutrients, Vol. 11, Pages 2867: Trends in Magnesium Intake among Hispanic Adults, the National Health and Nutrition Examination Survey (NHANES) 1999–2014 Nutrients doi: 10.3390/nu11122867 Authors: Jialiang Liu Yuhan Huang Qi Dai Kimberly G. Fulda Shande Chen Meng-Hua Tao This study aimed at examining trends in magnesium intake among U.S. Hispanic adults stratified by gender, Hispanic origins, age, and poverty income ratio (PIR) level. Data on 9304 Hispanic adults aged...
Fri Nov 22, 2019 02:00
Nutrients, Vol. 11, Pages 2865: Parenteral Nutrition in Patients with Inflammatory Bowel Disease Systematic Review, Meta-Analysis and Meta-Regression Nutrients doi: 10.3390/nu11122865 Authors: Jose M. Comeche Iris Comino Cesare Altavilla Jose Tuells Ana Gutierrez-Hervas Pablo Caballero Inflammatory bowel disease (IBD) is a chronic disease mediated by the immune system and characterized by the inflammation of the gastrointestinal tract. This study is to understand how the...
Fri Nov 22, 2019 02:00
Nutrients, Vol. 11, Pages 2864: Thirst and Drinking Paradigms: Evolution from Single Factor Effects to Brainwide Dynamic Networks Nutrients doi: 10.3390/nu11122864 Authors: Lawrence E. Armstrong Stavros A. Kavouras The motivation to seek and consume water is an essential component of human fluid–electrolyte homeostasis, optimal function, and health. This review describes the evolution of concepts regarding thirst and drinking behavior, made possible by magnetic resonance...
Fri Nov 22, 2019 02:00
Nutrients, Vol. 11, Pages 2866: The Effect of n-3 PUFA Binding Phosphatidylglycerol on Metabolic Syndrome-Related Parameters and n-3 PUFA Accretion in Diabetic/Obese KK-Ay Mice Nutrients doi: 10.3390/nu11122866 Authors: Liping Chen Naoki Takatani Fumiaki Beppu Kazuo Miyashita Masashi Hosokawa n-3 Polyunsaturated fatty acid binding phospholipids (n-3 PUFA-PLs) are known to be potent carriers of n-3 PUFAs and provide health benefits. We previously prepared n-3 PUFA binding...
Fri Nov 22, 2019 02:00
Nutrients, Vol. 11, Pages 2863: Interactions between DRD2/ANKK1 TaqIA Polymorphism and Dietary Factors Influence Plasma Triglyceride Concentrations in Diabetic Patients from Western Mexico: A Cross-sectional Study Nutrients doi: 10.3390/nu11122863 Authors: Omar Ramos-Lopez Roberto Mejia-Godoy Kevin J. Frías-Delgadillo Rafael Torres-Valadez Aurelio Flores-García Sergio Sánchez-Enríquez Pedro Aguiar-García Erika Martínez-López Eloy A. Zepeda-Carrillo This study...
Fri Nov 22, 2019 02:00
Pathogens, Vol. 8, Pages 259: Entry of Scotophilus Bat Coronavirus-512 and Severe Acute Respiratory Syndrome Coronavirus in Human and Multiple Animal Cells Pathogens doi: 10.3390/pathogens8040259 Authors: Yi-Ning Chen Hsiao-Chin Hsu Sheng-Wei Wang Hao-Chiang Lien Hsin-Ti Lu Sheng-Kai Peng Bats are natural reservoirs of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV). Scotophilus bat CoV-512 demonstrates potential...
Fri Nov 22, 2019 02:00
Pathogens, Vol. 8, Pages 258: Antiviral Activity of Germacrone against Pseudorabies Virus in Vitro Pathogens doi: 10.3390/pathogens8040258 Authors: Wanting He Xiaofeng Zhai Jingyin Su Rui Ye Yuna Zheng Shuo Su Pseudorabies virus (PRV), a member of the Herpesviridae, is the causative agent of an acute infectious disease in a variety of animals. The emergence of a novel variant strain brought huge economic losses to the pig industry since classical vaccine strains were not...
Fri Nov 22, 2019 02:00
Pathogens, Vol. 8, Pages 260: Effects of Shape and Size of Cobalt Phosphate Nanoparticles against Acanthamoeba castellanii Pathogens doi: 10.3390/pathogens8040260 Authors: Ayaz Anwar Leong Chi Fung Areeba Anwar Priyanka Jagadish Arshid Numan Mohammad Khalid Syed Shahabuddin Ruqaiyyah Siddiqui Naveed Ahmed Khan T4 genotype Acanthamoeba are opportunistic pathogens that cause two types of infections, including vision-threatening Acanthamoeba keratitis (AK) and a...
Fri Nov 22, 2019 02:00
Pathogens, Vol. 8, Pages 257: Animal Models of Type III Secretion System-Mediated Pathogenesis Pathogens doi: 10.3390/pathogens8040257 Authors: Julia A. Hotinger Aaron E. May The type III secretion system (T3SS) is a conserved virulence factor used by many Gram-negative pathogenic bacteria and has become an important target for anti-virulence drugs. Most T3SS inhibitors to date have been discovered using in vitro screening assays. Pharmacokinetics and other important characteristics...
Fri Nov 22, 2019 02:00
Pathogens, Vol. 8, Pages 256: Whole Genome Sequencing of Aggregatibacter actinomycetemcomitans Cultured from Blood Stream Infections Reveals Three Major Phylogenetic Groups Including a Novel Lineage Expressing Serotype a Membrane O Polysaccharide Pathogens doi: 10.3390/pathogens8040256 Authors: Signe Nedergaard Carl M. Kobel Marie B. Nielsen Rikke T. Møller Anne B. Jensen Niels Nørskov-Lauritsen Twenty-nine strains of Aggregatibacter actinomycetemcomitans cultured from...
Fri Nov 22, 2019 02:00
Pharmaceutics, Vol. 11, Pages 626: Repeat-Dose Toxicity Study Using the AFPL1-Conjugate Nicotine Vaccine in Male Sprague Dawley Rats Pharmaceutics doi: 10.3390/pharmaceutics11120626 Authors: Reynaldo Oliva Nya L. Fraleigh Jordan D. Lewicky Mildrey Fariñas Tamara Hernández Alexandrine L. Martel Ingrid Navarro García-Rivera Dagmar Reinaldo Acevedo Hoang-Thanh Le Tobacco smoking is the cause of 20% of Canadian deaths per year. Nicotine vaccines present a promising...
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Pharmaceutics, Vol. 11, Pages 625: A Novel Rheological Method to Assess Drug-Polymer Interactions Regarding Miscibility and Crystallization of Drug in Amorphous Solid Dispersions for Oral Drug Delivery Pharmaceutics doi: 10.3390/pharmaceutics11120625 Authors: Georgia Tsakiridou Christos Reppas Martin Kuentz Lida Kalantzi Solid dispersions provide a key technology to formulate poorly water-soluble drugs, and a main task of early development is appropriate selection of polymer....
Fri Nov 22, 2019 02:00
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