JCM, Vol. 8, Pages 1947: Acute Effects of Immersive Virtual Reality Exercise on Young Adults’ Situational Motivation Journal of Clinical Medicine doi: 10.3390/jcm8111947 Authors: Wenxi Liu Nan Zeng Zachary C. Pope Daniel J. McDonough Zan Gao The development of innovative technology, such as virtual reality (VR), has provided opportunities for promoting physical activity (PA) in a fun and engaging manner. The purpose of this study was to examine differences in young adults’...
JCM, Vol. 8, Pages 1945: Conversion Surgery for Advanced Pancreatic Cancer Journal of Clinical Medicine doi: 10.3390/jcm8111945 Authors: Thomas Hank Oliver Strobel While primarily unresectable locally advanced pancreatic cancer (LAPC) used to be an indication for palliative therapy, a strategy of neoadjuvant therapy (NAT) and conversion surgery is being increasingly used after more effective chemotherapy regimens have become available for pancreatic ductal adenocarcinoma. While high-level...
JCM, Vol. 8, Pages 1944: Exciting Opportunities in Nuclear Medicine Imaging and Therapy Journal of Clinical Medicine doi: 10.3390/jcm8111944 Authors: Constantin Lapa Nuclear medicine has experienced a number of unprecedented developments in recent years. Above all, the concept of “theranostics”, the combination of a predictive biomarker with a therapeutic agent, has been a central part of this success. For example, a phase III randomized, controlled trial provided...
JCM, Vol. 8, Pages 1943: Exacerbation of Hangover Symptomology Significantly Corresponds with Heavy and Chronic Alcohol Drinking: A Pilot Study Journal of Clinical Medicine doi: 10.3390/jcm8111943 Authors: Vatsalya Vatsalya Hamza Z. Hassan Maiying Kong Bethany L. Stangl Melanie L. Schwandt Veronica Y. Schmidt-Teron Joris C. Verster Vijay A. Ramchandani Craig J. McClain Alcohol hangover is a combination of mental, sympathetic, and physical symptoms experienced...
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JFB, Vol. 10, Pages 49: Design of Silk-Elastin-Like Protein Nanoparticle Systems with Mucoadhesive Properties Journal of Functional Biomaterials doi: 10.3390/jfb10040049 Authors: Parker Wu McKay Xu Kaplan Transmucosal drug delivery is a promising avenue to improve therapeutic efficacy through localized therapeutic administration. Drug delivery systems that increase retention in the mucosal layer are needed to improve efficiency of such transmucosal platforms. However,...
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JoF, Vol. 5, Pages 105: Detection of Fusarium Species in Clinical Specimens by Probe-Based Real-Time PCR Journal of Fungi doi: 10.3390/jof5040105 Authors: Jan Springer Grit Walther Volker Rickerts Axel Hamprecht Birgit Willinger Daniel Teschner Hermann Einsele Oliver Kurzai Juergen Loeffler The mold Fusarium is a ubiquitous fungus causing plant, animal and human infections. In humans, Fusarium spp. are the major cause of eye infections in patients wearing contact...
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Medicina, Vol. 55, Pages 734: Biomaterials in Gastroenterology: A Critical Overview Medicina doi: 10.3390/medicina55110734 Authors: Goldis Goldis Chirila In spite of the large diversity of diagnostic and interventional devices associated with gastrointestinal endoscopic procedures, there is little information on the impact of the biomaterials (metals, polymers) contained in these devices upon body tissues and, indirectly, upon the treatment outcomes. Other biomaterials for...
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Membranes, Vol. 9, Pages 151: Effects of a Novel Adsorbent on Membrane Fouling by Natural Organic Matter in Drinking Water Treatment Membranes doi: 10.3390/membranes9110151 Authors: Lelum D. Manamperuma Eilen A. Vik Mark Benjamin Zhenxiao Cai Jostein Skjefstad Irreversible fouling of water filtration membranes reduces filter longevity and results in higher costs associated with membrane maintenance and premature replacement. The search for effective pretreatment methods to...
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Metabolites, Vol. 9, Pages 278: Historical Biobanks in Breast Cancer Metabolomics— Challenges and Opportunities Metabolites doi: 10.3390/metabo9110278 Authors: Torfinn S. Madssen Maria D. Cao Arne V. Pladsen Lars Ottestad Kristine K. Sahlberg Tone F. Bathen Guro F. Giskeødegård Background: Metabolomic characterization of tumours can potentially improve prediction of cancer prognosis and treatment response. Here, we describe efforts to validate previous metabolomic findings...
Metabolites, Vol. 9, Pages 277: Evaluation of Dried Blood Spot Sampling for Clinical Metabolomics: Effects of Different Papers and Sample Storage Stability Metabolites doi: 10.3390/metabo9110277 Authors: Trifonova Maslov Balashova Lokhov The dried blood spot (DBS) sampling has a lot of advantages in comparison with the “standard” venous blood collecting, such as small collection volume, painless and easy sample collection with minimal training required,...
Metabolites, Vol. 9, Pages 276: Metabolomics Applied to the Study of Extracellular Vesicles Metabolites doi: 10.3390/metabo9110276 Authors: Charles Williams Mari Palviainen Niels-Christian Reichardt Pia R.-M. Siljander Juan M. Falcón-Pérez Cell-secreted extracellular vesicles (EVs) have rapidly gained prominence as sources of biomarkers for non-invasive biopsies, owing to their ubiquity across human biofluids and physiological stability. There are many characterisation studies...
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Microorganisms, Vol. 7, Pages 559: Cell-Wall Hydrolases as Antimicrobials against Staphylococcus Species: Focus on Sle1Microorganisms doi: 10.3390/microorganisms7110559Authors: Vermassen Talon Andant Provot Desvaux LeroySome staphylococcal species are opportunistic pathogens of humans and/or animals with Staphylococcus epidermidis as one of the most important. It causes a broad spectrum of diseases in humans and animals. This species is able to form biofilms and has developed antibiotic resistance,...
Microorganisms, Vol. 7, Pages 558: Characteristics of a Colistin-Resistant Escherichia coli ST695 Harboring the Chromosomally-Encoded mcr-1 GeneMicroorganisms doi: 10.3390/microorganisms7110558Authors: Peng Hu Li Li Jia Zhang Wu Chen WangEnterobacteriaceae having chromosomally-encoded mcr-1 is rarely reported. In this study, we recovered a chromosomal mcr-1 carrying Escherichia coli, designated HeN100, from the feces of a diarrheal pig in China. Antimicrobial susceptibility testing showed that HeN100...
Microorganisms, Vol. 7, Pages 557: Sexually Transmitted Infections and Behavioral Determinants of Sexual and Reproductive Health in the Allahabad District (India) Based on Data from the ChlamIndia StudyMicroorganisms doi: 10.3390/microorganisms7110557Authors:Pierre P. M. ThomasJay YadavRajiv KantElena AmbrosinoSmita SrivastavaGurpreet BatraArvind DayalNidhi MasihAkash PandeySaurav SahaRoel HeijmansJonathan A. LalServaas A. MorréBackground: Sexually transmitted infections (STIs), like Chlamydia trachomatis...
Microorganisms, Vol. 7, Pages 554: Prevalence, Distribution, and Phylogeny of Type Two Toxin-Antitoxin Genes Possessed by Cronobacter Species where C. sakazakii Homologs Follow Sequence Type LineagesMicroorganisms doi: 10.3390/microorganisms7110554Authors:Samantha FinkelsteinFlavia NegreteHyein JangJayanthi GangiredlaMark MammelIsha R. PatelHannah R. ChaseJungHa WooYouYoung LeeCaroline Z. WangLeah WeinsteinBen D. TallGopal R. GopinathCronobacter species are a group of foodborne pathogenic bacteria...
Microorganisms, Vol. 7, Pages 555: Asymmetrical Flow Field-Flow Fractionation on Virus and Virus-Like Particle ApplicationsMicroorganisms doi: 10.3390/microorganisms7110555Authors:Katri EskelinMinna M. PoranenHanna M. OksanenAsymmetrical flow field-flow fractionation (AF4) separates sample components based on their sizes in the absence of a stationary phase. It is well suited for high molecular weight samples such as virus-sized particles. The AF4 experiment can potentially separate molecules within...
Microorganisms, Vol. 7, Pages 556: Combined Use of the Ab105-2φΔCI Lytic Mutant Phage and Different Antibiotics in Clinical Isolates of Multi-Resistant Acinetobacter baumanniiMicroorganisms doi: 10.3390/microorganisms7110556Authors:Lucia BlascoAnton AmbroaMaria LopezLaura Fernandez-GarciaInes BleriotRocio TrastoyJose Ramos-VivasTom CoenyeFelipe Fernandez-CuencaJordi VilaLuis Martinez-MartinezJesus Rodriguez-BañoAlvaro PascualJose Miguel CisnerosJeronimo PachonGerman BouMaria TomasPhage therapy is...
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Molbank, Vol. 2019, Article M1088: 3-(3,4-Dimethoxyphenyl)-5-(2-fluorophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole Molbank doi: 10.3390/M1088 Authors: Adel Zamri Hilwan Y. Teruna Sri Wulansari Noval Herfindo Neni Frimayanti Ihsan Ikhtiarudin A new analogue of fluorinated pyrazoline (compound 1) has been synthesized via one-pot three-component reaction under microwave irradiation. The structure of compound 1 has been established by spectroscopy analysis, including UV, FT-IR,...
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Molecules, Vol. 24, Pages 4092: Structural Analysis, Molecular Modelling and Preliminary Competition Binding Studies of AM-DAN as a NMDA Receptor PCP-Site Fluorescent Ligand Molecules doi: 10.3390/molecules24224092 Authors: Sethu Ndzibongwana Samukelo Ngobese Ahmad Sayed Ciniso Shongwe Simon White-Phillips Jacques Joubert Excitotoxicity related to the dysfunction of the N-methyl-d-aspartate receptor (NMDAR) has been indicated to play an integral role in the pathophysiology...
Molecules, Vol. 24, Pages 4093: The Anti-Aging Potential of Neohesperidin and Its Synergistic Effects with Other Citrus Flavonoids in Extending Chronological Lifespan of Saccharomyces Cerevisiae BY4742 Molecules doi: 10.3390/molecules24224093 Authors: Chunxia Guo Hua Zhang Xin Guan Zhiqin Zhou The anti-aging activity of many plant flavonoids, as well as their mechanisms of action, have been explored in the current literature. However, the studies on the synergistic effects between...
Molecules, Vol. 24, Pages 4090: [b]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors Molecules doi: 10.3390/molecules24224090 Authors: Christian Lechner Maren Flaßhoff Hannes Falke Lutz Preu Nadége Loaëc Laurent Meijer Stefan Knapp Apirat Chaikuad Conrad Kunick Since hyperactivity of the protein kinase DYRK1A is linked to several neurodegenerative disorders, DYRK1A inhibitors have been suggested as potential therapeutics for Down syndrome and...
Molecules, Vol. 24, Pages 4088: Anti-Inflammatory Activities of Isogosferol, a Furanocoumarin Isolated from Citrus junos Seed Shells through Bioactivity-Guided Fractionation Molecules doi: 10.3390/molecules24224088 Authors: Song Jo Shin Lim Lee Jeong Lee Citrus junos Tanaka is a traditional medicine for treating coughs, dyspepsia, diabetes, asthma, neuralgia, and inflammatory disorders, and is distributed in Asia, especially in Korea, Japan, and China. This study...
Molecules, Vol. 24, Pages 4089: Automated Photochemically Induced Method for the Quantitation of the Neonicotinoid Thiacloprid in Lettuce Molecules doi: 10.3390/molecules24224089 Authors: J. Jiménez-López E.J. Llorent-Martínez S. Martínez-Soliño A. Ruiz-Medina In this work, we present an automated luminescence sensor for the quantitation of the insecticide thiacloprid, one of the main neonicotinoids, in lettuce samples. A simple and automated manifold was constructed, using...
Molecules, Vol. 24, Pages 4087: Sequential Response of Sage Antioxidant Metabolism to Chilling Treatment Molecules doi: 10.3390/molecules24224087 Authors: Andrzej Kalisz Agnieszka Sękara Robert Pokluda Aleš Jezdinský Jarmila Neugebauerová Katalin Angéla Slezák Edward Kunicki Chilling influences the growth and metabolism of plants. The physiological response and acclimatization of genotypes in relation to stress stimulus can be different. Two sage cultivars: ‘Icterina’...
Molecules, Vol. 24, Pages 4086: Indigo Naturalis Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating the Intestinal Microbiota Community Molecules doi: 10.3390/molecules24224086 Authors: Yan-Ni Liang Jin-Gao Yu Dong-Bo Zhang Zhen Zhang Lang-Lang Ren Lu-Han Li Zheng Wang Zhi-Shu Tang Indigo naturalis (IN) is a traditional Chinese medicine, named Qing-Dai, which is extracted from indigo plants and has been used to treat patients with inflammatory...
Molecules, Vol. 24, Pages 4085: Investigation of Molecular Details of Keap1-Nrf2 Inhibitors Using Molecular Dynamics and Umbrella Sampling Techniques Molecules doi: 10.3390/molecules24224085 Authors: Ashwini Machhindra Londhe Changdev Gorakshnath Gadhe Sang Min Lim Ae Nim Pae In this study, we investigate the atomistic details of Keap1-Nrf2 inhibitors by in-depth modeling techniques, including molecular dynamics (MD) simulations, and the path-based free energy method of umbrella...
Molecules, Vol. 24, Pages 4084: Speciation Studies of Bifunctional 3-Hydroxy-4-Pyridinone Ligands in the Presence of Zn2+ at Different Ionic Strengths and Temperatures Molecules doi: 10.3390/molecules24224084 Authors: Anna Irto Paola Cardiano Salvatore Cataldo Karam Chand Rosalia Maria Cigala Francesco Crea Concetta De Stefano Giuseppe Gattuso Nicola Muratore Alberto Pettignano Silvio Sammartano M. Amélia Santos The acid–base properties of two...
Molecules, Vol. 24, Pages 4083: Unusual Fluorescence Behavior of Pyrene-Amine Containing Dendrimers Molecules doi: 10.3390/molecules24224083 Authors: Andrea Ruiu Mireille Vonlanthen Sandra M. Rojas-Montoya Israel González-Méndez Ernesto Rivera A new class of pyrene-based dendrimers, characterized by the presence of a 1,4,7,10-Tetraazacyclododecane (cyclen) unit as the core, was studied by SSF (steady-state fluorescence) and SPC (single-photon counting fluorescence). The photophysical...
Molecules, Vol. 24, Pages 4082: Synthesis, Characterization, Antimicrobial Activity, and Genotoxicity Assessment of Two Heterocyclic Compounds Containing 1,2,3-Selena- or 1,2,3-Thiadiazole Rings Molecules doi: 10.3390/molecules24224082 Authors: Mousa L. Al-Smadi Reem Mansour Amjad Mahasneh Omar F. Khabour Majed M. Masadeh Karem H. Alzoubi New 1,2,3-thiadiazole and 1,2,3-selenadiazole derivatives, (4-[4-((4-bromobenzyl)oxy)-phenyl]-1,2,3-thiadiazole (5a), 4-[4-((4-chlorobenzyl)oxy)-phenyl]-1,2,3-thiadiazole...
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Nanomaterials, Vol. 9, Pages 1607: Recent Advances and Future Prospects in Spark Plasma Sintered Alumina Hybrid Nanocomposites Nanomaterials doi: 10.3390/nano9111607 Authors: Saheb Hayat Hassan Although ceramics have many advantages when compared to metals in specific applications, they could be more widely applied if their low properties (fracture toughness, strength, and electrical and thermal conductivities) are improved. Reinforcing ceramics by two nano-phases that have...
Nanomaterials, Vol. 9, Pages 1608: Bare Iron Oxide Nanoparticles: Surface Tunability for Biomedical, Sensing and Environmental Applications Nanomaterials doi: 10.3390/nano9111608 Authors: Magro Vianello Surface modification is widely assumed as a mandatory prerequisite for the real applicability of iron oxide nanoparticles. This is aimed to endow prolonged stability, electrolyte and pH tolerance as well as a desired specific surface chemistry for further functionalization to these...
Nanomaterials, Vol. 9, Pages 1606: A Metabolomic Approach for the In Vivo Study of Gold Nanospheres and Nanostars after a Single-Dose Intravenous Administration to Wistar Rats Nanomaterials doi: 10.3390/nano9111606 Authors: Enea Araújo Almeida Soares Gonçalves-Monteiro Pinho Pereira Bastos Carmo Gold nanoparticles (AuNPs) are promising nanoplatforms for drug therapy, diagnostic and imaging. However, biological comparison studies for different types of...
Nanomaterials, Vol. 9, Pages 1605: Nanometer Ammonium Perchlorate and Ammonium Nitrate Prepared with 2D Network Structure via Rapid Freezing Technology Nanomaterials doi: 10.3390/nano9111605 Authors: Yi Wang Xiaolan Song Fengsheng Li Nanometer (nano) ammonium perchlorate (AP) and ammonium nitrate (AN) were prepared with 2D network structures by the ultra-low temperature spray method. Scanning electron microscopy (SEM), X-ray diffractometry (XRD), differential scanning calorimetry...
Nanomaterials, Vol. 9, Pages 1604: Biogenic Silver Nanoparticles for Trace Colorimetric Sensing of Enzyme Disrupter Fungicide Vinclozolin Nanomaterials doi: 10.3390/nano9111604 Authors: Masood Hussain Ayman Nafady Sirajuddin Ahmet Avcı Erol Pehlivan Jan Nisar Syed Tufail Hussain Sherazi Aamna Balouch Muhammad Raza Shah Omar A. Almaghrabi Muhammad Anwar Ul-Haq We report a novel, simple, efficient, and green protocol for biogenic synthesis of silver nanoparticles...
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Nutrients, Vol. 11, Pages 2750: Effect of Dietary Sodium and Potassium Intake on the Mobilization of Bone Lead among Middle-Aged and Older Men: The Veterans Affairs Normative Aging Study Nutrients doi: 10.3390/nu11112750 Authors: Xin Wang Douglas Kim Katherine L. Tucker Marc G. Weisskopf David Sparrow Howard Hu Sung Kyun Park Bone is a major storage site as well as an endogenous source of lead in the human body. Dietary sodium and potassium intake may play a role in...
Nutrients, Vol. 11, Pages 2748: Bone Mineral Metabolism Status, Quality of Life, and Muscle Strength in Older People Nutrients doi: 10.3390/nu11112748 Authors: Verde Giaquinta Sainz Ondina Araque As the relationship between vitamin D and various diseases or health conditions has become known, interest in the contribution of vitamin D to overall health-related quality of life (QoL) has increased. We examined the relationship between vitamin D status and QoL in 273 participants...
Nutrients, Vol. 11, Pages 2749: Low Carbohydrate and Low-Fat Diets: What We Don't Know and Why we Should Know It Nutrients doi: 10.3390/nu11112749 Authors: Seid Rosenbaum In the 1940s, the diet-heart hypothesis proposed that high dietary saturated fat and cholesterol intake promoted coronary heart disease in “at-risk“ individuals. This hypothesis prompted federal recommendations for a low-fat diet for “high risk” patients and as a preventive...
Nutrients, Vol. 11, Pages 2747: Black Ginseng and Ginsenoside Rb1 Promote Browning by Inducing UCP1 Expression in 3T3-L1 and Primary White Adipocytes Nutrients doi: 10.3390/nu11112747 Authors: Seon-Joo Park Miey Park Anshul Sharma Kihyun Kim Hae-Jeung Lee In this study, we investigated the effects of black ginseng (BG) and ginsenoside Rb1, which induced browning effects in 3T3-L1 and primary white adipocytes (PWATs) isolated from C57BL/6 mice. BG and Rb1 suppressed the expressions...
Nutrients, Vol. 11, Pages 2746: The ‘Voice’ of Key Stakeholders in a School Food and Drink Intervention in Two Secondary Schools in NE England: Findings from a Feasibility Study Nutrients doi: 10.3390/nu11112746 Authors: McSweeney Bradley Adamson Spence Background: Overweight/obesity affects one-third of UK 11–15-year olds. Individually focussed interventions alone have limited effectiveness. Food choice architecture approaches increase the visibility and convenience...
Nutrients, Vol. 11, Pages 2745: Effects of Doenjang, a Traditional Korean Soybean Paste, with High-Salt Diet on Blood Pressure in Sprague–Dawley Rats Nutrients doi: 10.3390/nu11112745 Authors: Eun-Gyung Mun Jung Eun Park Youn-Soo Cha Fermented foods in Korea contain a lot of salt. Although salt is reported to exacerbate health trouble, fermented foods have beneficial effects. We hypothesized that doenjang could reduce blood pressure in Sprague–Dawley (SD) rats fed a high-salt...
Nutrients, Vol. 11, Pages 2743: Meeting Minimum ESPEN Energy Recommendations Is Not Enough to Maintain Muscle Mass in Head and Neck Cancer Patients Nutrients doi: 10.3390/nu11112743 Authors: Benjamin McCurdy Sara Nejatinamini Brock J. Debenham Mirey Álvarez-Camacho Catherine Kubrak Wendy V. Wismer Vera C. Mazurak The relationship between dietary intake and body composition changes during cancer treatment has not been well characterized. The aim of this study was to...
Nutrients, Vol. 11, Pages 2744: Effects of Some Food Components on Non-Alcoholic Fatty Liver Disease Severity: Results from a Cross-Sectional Study Nutrients doi: 10.3390/nu11112744 Authors: Antonella Mirizzi Isabella Franco Carla Maria Leone Caterina Bonfiglio Raffaele Cozzolongo Maria Notarnicola Vito Giannuzzi Valeria Tutino Valentina De Nunzio Irene Bruno Claudia Buongiorno Angelo Campanella Valentina Deflorio Annamaria Pascale Filippo Procino...
Nutrients, Vol. 11, Pages 2740: Dietary Patterns Independent of Fast Food Are Associated with Obesity among Korean Adults: Korea National Health and Nutrition Examination Survey 2010–2014 Nutrients doi: 10.3390/nu11112740 Authors: Do-Yeon Kim Ahleum Ahn Hansongyi Lee Jaekyung Choi Hyunjung Lim Few studies have examined the multifaceted aspects of fast food consumption and dietary patterns for their effects on obesity. We examined the independent associations of obesity with...
Nutrients, Vol. 11, Pages 2741: Proposal for an Empirical Japanese Diet Score and the Japanese Diet Pyramid Nutrients doi: 10.3390/nu11112741 Authors: Masao Kanauchi Kimiko Kanauchi A traditional Japanese diet (JD) has been widely regarded as healthy, contributing to longevity. The modern Japanese lifestyle has become markedly westernized, and it is speculated that the number of people who eat JD is decreasing. A simple evaluation of people with low adherence to JD will help improve...
Nutrients, Vol. 11, Pages 2739: Nutritional Assessment in Inflammatory Bowel Disease (IBD)—Development of the Groningen IBD Nutritional Questionnaires (GINQ) Nutrients doi: 10.3390/nu11112739 Authors: Vera Peters Behrooz Z Alizadeh Jeanne HM de Vries Gerard Dijkstra Marjo JE Campmans-Kuijpers Diet plays a key role in the complex etiology and treatment of inflammatory bowel disease (IBD). Most existing nutritional assessment tools neglect intake of important foods consumed...
Nutrients, Vol. 11, Pages 2742: Spanish Consumer Purchase Behaviour and Stated Preferences for Yoghurts with Nutritional and Health Claims Nutrients doi: 10.3390/nu11112742 Authors: Petjon Ballco Tiziana De Magistris Nutritional and health claims are a useful tool for promoting healthier food choices and prevent non-communicable disease[s] (NCDs). Exhaustive literature that has investigated consumer evaluation of the presence of nutritional and/or health claim(s) during the decision-making...
Nutrients, Vol. 11, Pages 2738: Nutritional Content According to the Presence of Front of Package Marketing Strategies: The Case of Ultra-Processed Snack Food Products Purchased in Costa Rica Nutrients doi: 10.3390/nu11112738 Authors: Tatiana Gamboa-Gamboa Adriana Blanco-Metzler Stefanie Vandevijvere Manuel Ramirez-Zea Maria F. Kroker-Lobos The industry uses nutrition and health claims, premium offers, and promotional characters as marketing strategies (MS). The inclusion...
Nutrients, Vol. 11, Pages 2737: The Importance of Lactose in the Human Diet: Outcomes of a Mexican Consensus Meeting Nutrients doi: 10.3390/nu11112737 Authors: Enrique Romero-Velarde Dagoberto Delgado-Franco Mariana García-Gutiérrez Carmen Gurrola-Díaz Alfredo Larrosa-Haro Ericka Montijo-Barrios Frits A. J. Muskiet Belinda Vargas-Guerrero Jan Geurts Lactose is a unique component of breast milk, many infant formulas and dairy products, and is widely used in pharmaceutical...
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Pathogens, Vol. 8, Pages 233: Quantification of Enterocytozoon hepatopenaei (EHP) in Penaeid Shrimps from Southeast Asia and Latin America Using TaqMan Probe-Based Quantitative PCR Pathogens doi: 10.3390/pathogens8040233 Authors: Patharapol Piamsomboon Seong-Kyoon Choi Bambang Hanggono Yani Lestari Nuraini Fatma Wati Kathy F. J. Tang Song Park Dongmi Kwak Man Hee Rhee Jee Eun Han Ji Hyung Kim We developed a qPCR assay based on the β-tubulin gene...
Pathogens, Vol. 8, Pages 232: Immunohistochemical Expression Patterns of Inflammatory Cells Involved in Chronic Hyperplastic Candidosis Pathogens doi: 10.3390/pathogens8040232 Authors: Ailish Williams David Williams Helen Rogers Xiaoqing Wei Michael Lewis Sue Wozniak Damian Farnell Adam Jones The profile of the inflammatory cell infiltrate in chronic hyperplastic candidosis (CHC) was determined in oral mucosal biopsies by immunohistochemistry. One tonsillar tissue...
Pathogens, Vol. 8, Pages 230: Pyrazinoic Acid Inhibits the Bifunctional Enzyme (Rv2783) in Mycobacterium tuberculosis by Competing with tmRNA Pathogens doi: 10.3390/pathogens8040230 Authors: Lei He Peng Cui Wanliang Shi Qiong Li Wenhong Zhang Min Li Ying Zhang Pyrazinamide (PZA) is a key drug for tuberculosis treatment. The active form of PZA, pyrazinoic acid (POA), appears to inhibit multiple targets in M. tuberculosis. Recently, the bifunctional enzyme Rv2783 was...
Pathogens, Vol. 8, Pages 231: A Single and Un-Adjuvanted Dose of a Chimpanzee Adenovirus-Vectored Vaccine against Chikungunya Virus Fully Protects Mice from Lethal Disease Pathogens doi: 10.3390/pathogens8040231 Authors: Rafael Kroon Campos Lorena Preciado-Llanes Sasha R. Azar Cesar Lopez-Camacho Arturo Reyes-Sandoval Shannan L. Rossi The mosquito-borne chikungunya virus (CHIKV) has become a major global health problem. Upon infection, chikungunya fever (CHIKF) can result...
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Pharmaceuticals, Vol. 12, Pages 168: Chemical Probes for the Adenosine Receptors Pharmaceuticals doi: 10.3390/ph12040168 Authors: Stephanie Federico Lucia Lassiani Giampiero Spalluto Research on the adenosine receptors has been supported by the continuous discovery of new chemical probes characterized by more and more affinity and selectivity for the single adenosine receptor subtypes (A1, A2A, A2B and A3 adenosine receptors). Furthermore, the development of new techniques for...
Pharmaceuticals, Vol. 12, Pages 167: In Vitro Assessment of Antimicrobial, Antioxidant, and Cytotoxic Properties of Saccharin–Tetrazolyl and –Thiadiazolyl Derivatives: The Simple Dependence of the pH Value on Antimicrobial Activity Pharmaceuticals doi: 10.3390/ph12040167 Authors: Luís M. T. Frija Epole Ntungwe Przemysław Sitarek Joana M. Andrade Monika Toma Tomasz Śliwiński Lília Cabral M. Lurdes S. Cristiano Patrícia Rijo Armando J. L. Pombeiro The antimicrobial,...
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Pharmaceutics, Vol. 11, Pages 603: A Direct Compression Matrix Made from Xanthan Gum and Low Molecular Weight Chitosan Designed to Improve Compressibility in Controlled Release Tablets Pharmaceutics doi: 10.3390/pharmaceutics11110603 Authors: Abu Fara Dadou Rashid Al-Obeidi Antonijevic Chowdhry Badwan The subject of our research is the optimization of direct compression (DC), controlled release drug matrices comprising chitosan/xanthan gum. The foregoing is...
Pharmaceutics, Vol. 11, Pages 602: Bone Morphogenic Protein 2-Loaded Porous Silicon Carriers for Osteoinductive Implants Pharmaceutics doi: 10.3390/pharmaceutics11110602 Authors: Michal Rosenberg Dekel Shilo Leonid Galperin Tal Capucha Karim Tarabieh Adi Rachmiel Ester Segal Bone morphogenetic proteins (BMPs) are probably the most important growth factors in bone formation and healing. However, the utilization of BMPs in clinical applications is mainly limited due to...
Pharmaceutics, Vol. 11, Pages 601: Synthesis, Principles, and Properties of Magnetite Nanoparticles for In Vivo Imaging Applications—A Review Pharmaceutics doi: 10.3390/pharmaceutics11110601 Authors: Wallyn Anton Vandamme The current nanotechnology era is marked by the emergence of various magnetic inorganic nanometer-sized colloidal particles. These have been extensively applied and hold an immense potential in biomedical applications including, for example, cancer therapy,...
Pharmaceutics, Vol. 11, Pages 600: Polymeric Nanoparticles Based on Tyrosine-Modified, Low Molecular Weight Polyethylenimines for siRNA Delivery Pharmaceutics doi: 10.3390/pharmaceutics11110600 Authors: Ewe Noske Karimov Aigner A major hurdle for exploring RNA interference (RNAi) in a therapeutic setting is still the issue of in vivo delivery of small RNA molecules (siRNAs). The chemical modification of polyethylenimines (PEIs) offers a particularly attractive avenue towards...
Pharmaceutics, Vol. 11, Pages 599: Encapsulation in Polymeric Nanoparticles Enhances the Enzymatic Stability and the Permeability of the GLP-1 Analog, Liraglutide, Across a Culture Model of Intestinal Permeability Pharmaceutics doi: 10.3390/pharmaceutics11110599 Authors: Ruba Ismail Alexandra Bocsik Gábor Katona Ilona Gróf Mária A. Deli Ildikó Csóka The potential of poly (lactic-co-glycolic acid) nanoparticles (PLGA NPs) to overcome the intestinal barrier that limits oral...
Pharmaceutics, Vol. 11, Pages 598: Perivascular and Perineural Pathways Involved in Brain Delivery and Distribution of Drugs after Intranasal Administration Pharmaceutics doi: 10.3390/pharmaceutics11110598 Authors: Jeffrey J. Lochhead Thomas P. Davis One of the most challenging aspects of treating disorders of the central nervous system (CNS) is the efficient delivery of drugs to their targets within the brain. Only a small fraction of drugs is able to cross the blood–brain...
Pharmaceutics, Vol. 11, Pages 597: Review of Advanced Hydrogel-Based Cell Encapsulation Systems for Insulin Delivery in Type 1 Diabetes Mellitus Pharmaceutics doi: 10.3390/pharmaceutics11110597 Authors: Albert Espona-Noguera Jesús Ciriza Alberto Cañibano-Hernández Gorka Orive Rosa María Hernández Laura Saenz del Burgo Jose Luis Pedraz : Type 1 Diabetes Mellitus (T1DM) is characterized by the autoimmune destruction of β-cells in the pancreatic islets. In this...
Pharmaceutics, Vol. 11, Pages 596: Preparation and In Vitro Evaluation of Neutron-Activated, Theranostic Samarium-153-Labeled Microspheres for Transarterial Radioembolization of Hepatocellular Carcinoma and Liver Metastasis Pharmaceutics doi: 10.3390/pharmaceutics11110596 Authors: Yin How Wong Hun Yee Tan Azahari Kasbollah Basri Johan Jeet Abdullah Chai Hong Yeong Introduction: Transarterial radioembolization (TARE) has been proven as an effective treatment for unresectable...
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Plants, Vol. 8, Pages 498: The Development and Characterization of Near-Isogenic and Pyramided Lines Carrying Resistance Genes to Brown Planthopper with the Genetic Background of Japonica Rice (Oryza sativa L.) Plants doi: 10.3390/plants8110498 Authors: Cuong D. Nguyen Holden Verdeprado Demeter Zita Sachiyo Sanada-Morimura Masaya Matsumura Parminder S. Virk Darshan S. Brar Finbarr G. Horgan Hideshi Yasui Daisuke Fujita The brown planthopper (BPH: Nilaparvata...
Plants, Vol. 8, Pages 497: Phenolic Composition and Antimicrobial Activity of Different Emirati Date (Phoenix dactylifera L.) Pits: A Comparative Study Plants doi: 10.3390/plants8110497 Authors: M. Iftikhar Hussain Mohammad H. Semreen Abdallah Shanableh Muhammad Nasir Khan Khattak Ismail Saadoun Islam M. Ahmady Muath Mousa Nora Darwish Wameed Radeef Sameh S. M. Soliman The biochemical composition, secondary metabolites (phenolic compounds, flavonoids) and antimicrobial...
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Publications, Vol. 7, Pages 64: Communication on the Science-Policy Interface: An Overview of Conceptual Models Publications doi: 10.3390/publications7040064 Authors: Nataliia Sokolovska Benedikt Fecher Gert G. Wagner This article focuses on scholarly discourse on the science-policy interface, and in particular on questions regarding how this discourse can be understood in the course of history and which lessons we can learn. We aim to structure the discourse, show kinships of...
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Religions, Vol. 10, Pages 627: Appropriation of Caste Spaces in Pakistan: The Theo-Politics of Short Stories in Sindhi Progressive Literature Religions doi: 10.3390/rel10110627 Authors: Ghulam Hussain This paper is an attempt to understand the appropriation of spaces of Dalits by Sindhi progressive activists and short story writers in Pakistan as they construct, or rather undermine, caste at the anvil of religion and gender to reframe their own theo-political agenda premised on political...
Religions, Vol. 10, Pages 626: ‘Can’t Hide from God’: On Forgiveness and the Unarmed Black Man Religions doi: 10.3390/rel10110626 Authors: Daniel A. Morris The recent deaths of unarmed black people, especially at the hands of law enforcement, have generated a troubling new ritual, in which the media publically asks family members if they will forgive their loved ones’ killers. The first task of this paper is to cast these petitions for forgiveness as ritual. The second task...
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Safety, Vol. 5, Pages 82: Decision-Making Processes Underlying Pedestrian Behaviors at Signalized Crossings: Part 2. Do Pedestrians Show Cultural Herding Behavior? Safety doi: 10.3390/safety5040082 Authors: Pelé Deneubourg Sueur Followership is generally defined as a strategy that evolved to solve social coordination problems, and particularly those involved in group movement. Followership behavior is particularly interesting in the context of road-crossing behavior because...
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Social Sciences, Vol. 8, Pages 311: Real-World Sustainable Citizenship between Political Consumerism and Material Practices Social Sciences doi: 10.3390/socsci8110311 Authors: Carolin V. Zorell Mundo Yang While the number of theoretical concepts surrounding sustainable citizenship, political consumerism and ethical lifestyles is rising continuously, this article is interested in how citizens themselves delineate sustainable citizenship through their practices. Asking which contours...
Social Sciences, Vol. 8, Pages 310: Subterranean Detention and Sanctuary from below: Canada’s Carceral Geographies Social Sciences doi: 10.3390/socsci8110310 Authors: Jen Bagelman Sasha Kovalchuk This paper begins with an account of Lucía Vega Jimenez, a Mexican woman who lived and worked in Metro Vancouver, Coast Salish Territories (Canada) and who died while held in detention in British Columbia’s Immigration Holding Centre. This article argues that Lucía’s...
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Societies, Vol. 9, Pages 77: Healthcare Financing in Rural Cameroon Societies doi: 10.3390/soc9040077 Authors: Nathanael Ojong In the global South, low-income populations are faced with frequent health shocks. Formal mechanisms to protect them against these shocks are absent or limited. Thus, what are the mechanisms used by low-income rural populations to finance healthcare? This paper draws on a qualitative study to examine the healthcare financing mechanisms of low-income rural populations...
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Sports, Vol. 7, Pages 235: Maximal Heart Rate for Swimmers Sports doi: 10.3390/sports7110235 Authors: Bjørn Harald Olstad Veronica Bjørlykke Daniela Schäfer Olstad The main purpose of this study was to identify whether a different protocol to achieve maximal heart rate should be used in sprinters when compared to middle-distance swimmers. As incorporating running training into swim training is gaining increased popularity, a secondary aim was to determine the difference in maximal...
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Toxins, Vol. 11, Pages 659: Comparative In Vitro Assessment of a Range of Commercial Feed Additives with Multiple Mycotoxin Binding Claims Toxins doi: 10.3390/toxins11110659 Authors: Kolawole Meneely Greer Chevallier Jones Connolly Elliott Contamination of animal feed with multiple mycotoxins is an ongoing and growing issue, as over 60% of cereal crops worldwide have been shown to be contaminated with mycotoxins. The present study was carried out to assess the...
Toxins, Vol. 11, Pages 658: Multiple Mycotoxins Determination in Food by LC-MS/MS: An International Collaborative Study Toxins doi: 10.3390/toxins11110658 Authors: Thomas Bessaire Claudia Mujahid Pascal Mottier Aurélien Desmarchelier An intercollaborative study was organized to evaluate the performance characteristics of a liquid chromatography tandem mass spectrometry procedure for the simultaneous determination of 12 mycotoxins in food, which were ochratoxin A, aflatoxins...
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Viruses, Vol. 11, Pages 1051: Detection and Cellular Tropism of Porcine Astrovirus Type 3 on Breeding Farms Viruses doi: 10.3390/v11111051 Authors: Gaurav Rawal Franco Matias Ferreyra Nubia R. Macedo Laura K. Bradner Karen M. Harmon Adam Mueller Grant Allison Daniel C. L. Linhares Bailey L. Arruda Astroviruses cause disease in a variety of species. Yet, little is known about the epidemiology of a majority of astroviruses including porcine astrovirus type 3 (PoAstV3),...
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Water, Vol. 11, Pages 2370: Urban Flood Hazard Modeling Using Self-Organizing Map Neural Network Water doi: 10.3390/w11112370 Authors: Rahmati Darabi Haghighi Stefanidis Kornejady Nalivan Bui Floods are the most common natural disaster globally and lead to severe damage, especially in urban environments. This study evaluated the efficiency of a self-organizing map neural network (SOMN) algorithm for urban flood hazard mapping in the case of Amol city, Iran. First,...
Water, Vol. 11, Pages 2369: Correlations of Stormwater Runoff and Quality: Urban Pavement and Property Value by Land Use at the Parcel Level in a Small Sized American City Water doi: 10.3390/w11112369 Authors: Zhou As the urban environment keeps growing, stormwater management programs have been adopted to address unregulated nonpoint runoff and pollutants across the world. Extensive studies on stormwater runoff and quality at smaller spatial scales exist, but are rare at larger spatial...
Water, Vol. 11, Pages 2368: Space–Time Kriging of Precipitation: Modeling the Large-Scale Variation with Model GAMLSS Water doi: 10.3390/w11112368 Authors: Elias Silva de Medeiros Renato Ribeiro de Lima Ricardo Alves de Olinda Leydson G. Dantas Carlos Antonio Costa dos Santos Knowing the dynamics of spatial–temporal precipitation distribution is of vital significance for the management of water resources, in highlight, in the northeast region of Brazil (NEB). Several...
Water, Vol. 11, Pages 2367: Assessment of the Effects of Wastewater Treatment Plant Modernization by Means of the Field Olfactometry Method Water doi: 10.3390/w11112367 Authors: Andrzej Kulig Mirosław Szyłak-Szydłowski Methodological aspects of odor studies in ex-post analyses for Polish wastewater management facilities were analyzed based on the example of a modernized and enlarged wastewater treatment plant (WWTP) in Mazovia, in the vicinity of the Warsaw agglomeration. It is a...
Water, Vol. 11, Pages 2366: staRdom: Versatile Software for Analyzing Spectroscopic Data of Dissolved Organic Matter in R Water doi: 10.3390/w11112366 Authors: Matthias Pucher Urban Wünsch Gabriele Weigelhofer Kathleen Murphy Thomas Hein Daniel Graeber The roles of dissolved organic matter (DOM) in microbial processes and nutrient cycles depend on its composition, which requires detailed measurements and analyses. We introduce a package for R, called staRdom (“spectroscopic...
Water, Vol. 11, Pages 2364: Phosphate Induced Arsenic Mobilization as a Potentially Effective In-Situ Remediation Technique—Preliminary Column Tests Water doi: 10.3390/w11112364 Authors: Martin V. Maier Yvonne Wolter Daniel Zentler Christian Scholz Charlotte N. Stirn Margot Isenbeck-Schröter Arsenic (As) contamination of groundwater is commonly remediated by pump and treat. However, this technique is difficult to apply or maintain efficiently because the mobility of arsenic...
Water, Vol. 11, Pages 2365: Synergies within the Water-Energy-Food Nexus to Support the Integrated Urban Resources Governance Water doi: 10.3390/w11112365 Authors: Guijun Li Yongsheng Wang Yulong Li Rapid urbanization poses great challenges to water-energy-food nexus (WEF-Nexus) system, calling for integrative resources governance to improve the synergies between subsystems that constitute the Nexus. This paper explores the synergies within the WEF-Nexus in Shenzhen city while...
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